Orange Naturals Zinc + Vitamin C | 90 Vegan Capsules
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 capsule daily with food (adults 19+; see label for full directions) |
| Licensed Natural Health Product | NPN 80075970 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 50 MG ZINC + 400 MG VITAMIN C PER CAPSULE: Each vegan capsule provides 50 mg Zinc (zinc citrate) and 400 mg Vitamin C (ascorbic acid) - adults (19 years and older) take 1 capsule per day with food.
- HELPS TO MAINTAIN IMMUNE FUNCTION: Helps to maintain immune function, pairing a well-absorbed zinc citrate with a meaningful daily dose of vitamin C in one capsule.
- ZINC CITRATE - A WELL-ABSORBED FORM: Formulated with zinc citrate, a zinc salt shown in human research to be as well absorbed as zinc gluconate and better absorbed than zinc oxide.
- COPPER DEFICIENCY CAUTION - READ BEFORE USE: Zinc supplementation can cause a copper deficiency - if you are unsure whether you are taking enough copper, ask a healthcare practitioner prior to use.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80075970. The label states this product is vegan and GMO-free, with no artificial flavours, colours, preservatives or sweeteners, and free from dairy, soy, gluten, wheat and yeast.
Product Description
Zinc + Vitamin C - 50 mg Zinc Citrate + 400 mg Vitamin C for Daily Immune Support
Orange Naturals Zinc + Vitamin C pairs 50 mg Zinc (zinc citrate) with 400 mg Vitamin C (ascorbic acid) in one vegan capsule, taken once daily with food. Zinc citrate is a well-absorbed form of zinc, shown in human research to be absorbed as well as zinc gluconate. This product helps to maintain immune function and also carries a real caution around zinc and copper levels, see below. Licensed Natural Health Product NPN 80075970.
Zinc + Vitamine C d'Orange Naturals associe 50 mg de zinc (citrate de zinc) et 400 mg de vitamine C (acide ascorbique) dans une capsule végane, prise une fois par jour avec de la nourriture. Le citrate de zinc est une forme de zinc bien absorbée, démontrée par la recherche humaine comme aussi bien absorbée que le gluconate de zinc. Ce produit aide à maintenir les fonctions immunitaires et comporte aussi une mise en garde réelle sur le zinc et le cuivre, voir ci-dessous. NPN 80075970.
A Simple Daily Capsule for Immune Support
50 mg Zinc (citrate) + 400 mg Vitamin C per capsule - one vegan capsule daily with food, made in Canada
50 mg Zinc + 400 mg Vitamin C per Capsule
Each vegan capsule delivers Zinc (zinc citrate) and Vitamin C (ascorbic acid) - adults (19 years and older) take 1 capsule per day with food.
Clean, Simple, Canadian
Made without artificial colours, flavours, preservatives or sweeteners, and formulated in Canada under Health Canada's NPN licensing program.
Advanced Ingredients, Superior Results
Zinc and vitamin C have each been studied for their role in immune function, and zinc citrate specifically for how well it is absorbed - while zinc supplementation carries a real, well-documented caution around copper levels. Here is what the wider research explores.
Zinc (zinc citrate)
An essential trace mineral involved in normal immune function, delivered here as zinc citrate, a form shown in human research to be as well absorbed as zinc gluconate.
50 mg per capsule
Vitamin C (ascorbic acid)
An essential vitamin and antioxidant that supports immune cell function and collagen synthesis, and helps the body absorb zinc more efficiently.
400 mg per capsuleOrange Naturals Zinc + Vitamin C: Supplement Facts
Each vegan capsule contains:
- Vitamin C (ascorbic acid)400 mg
- Zinc (zinc citrate)50 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose.
Recommended Use or Purpose: Helps to maintain immune function.
Recommended Dose: Adults (19 years and older) - Take 1 capsule per day with food. Take a few hours before or after taking other medications.
Cautions and Warnings: Zinc supplementation can cause copper deficiency. Keep out of reach of children. Do not use if safety seal is broken.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque capsule végane contient :
- Vitamine C (acide ascorbique)400 mg
- Zinc (citrate de zinc)50 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Cellulose microcristalline, hypromellose, stéarate de magnésium.
Usage ou fins recommandés : Aide au maintien des fonctions immunitaires.
Posologie recommandée : Adultes (19 ans et plus) - Prendre 1 capsule par jour avec de la nourriture. Prendre quelques heures avant ou après la prise d'autres médicaments.
Mises en garde : Une supplémentation en zinc peut causer une carence en cuivre. Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.
NPN 80075970
Help support your immune function with Zinc + Vitamin C
Get Orange Naturals Zinc + Vitamin C on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Zinc + Vitamin C
50 mg Zinc (citrate) + 400 mg Vitamin C per vegan capsule - a well-absorbed zinc form, real adult dosing on the label, and a real zinc/copper caution you should read before use.
50 mg Zinc + 400 mg Vitamin C per Capsule
Each vegan capsule delivers Zinc (zinc citrate) and Vitamin C (ascorbic acid) - zinc citrate is shown in human research to be as well absorbed as zinc gluconate.
Helps to maintain immune function
Helps to maintain immune function, pairing zinc and vitamin C in one daily capsule.
One vegan capsule daily
Adults (19 years and older) take 1 capsule per day with food, a few hours before or after other medications.
Real cautions, made in Canada
Zinc supplementation can cause a copper deficiency - if you are unsure whether you are taking enough copper, ask a healthcare practitioner prior to use. NPN 80075970.
Inside every vegan capsule
50 mg Zinc (zinc citrate) and 400 mg Vitamin C (ascorbic acid) in one vegan capsule - adults (19 years and older) take 1 capsule per day with food.
How to use it
Adults (19 years and older)
Take 1 capsule per day with food.
Timing with other medications
Take a few hours before or after taking other medications or natural health products.
Read the caution before you start
Zinc supplementation can cause a copper deficiency - if you are unsure whether you are taking enough copper, ask a healthcare practitioner prior to use. Keep out of reach of children.
Check the safety seal
Do not use if the safety seal is broken.
What the research says about this formula's ingredients
Educational summaries of published research on zinc and vitamin C generally; not product-specific claims. Orange Naturals Zinc + Vitamin C's own authorized use under NPN 80075970 is that it helps to maintain immune function.
A 2024 Cochrane review of 34 trials found zinc may shorten an ongoing cold, mostly studied in adults
Pooling 34 randomized trials covering 8,526 participants (22 conducted in adults, 12 in children), this Cochrane review found little or no effect of zinc on preventing colds, but when zinc was used to treat an already-started cold there was a probable reduction in mean cold duration of about 2.4 days, alongside a probable increase in non-serious adverse events such as bad taste or nausea.
Systematic review and meta-analysis (Cochrane, n=8,526)An individual patient data meta-analysis in mostly working-age adults found zinc acetate lozenges cut colds short by about 3 days
Combining individual-level data from three placebo-controlled trials of zinc acetate lozenges in 199 cold patients (80 percent aged 20 to 50), this analysis found colds were shortened by 2.7 to 2.9 days on average compared with the roughly 7-day average duration in the placebo group, an effect that held consistently regardless of age, sex, smoking status or allergy history.
Individual patient data meta-analysis (n=199, adults)A classic randomized trial in working adults found zinc gluconate lozenges nearly halved the time to full cold recovery
In 100 employees of a large medical center who started zinc gluconate lozenges within 24 hours of cold symptoms, time to complete symptom resolution was significantly shorter than placebo (median 4.4 versus 7.6 days), with fewer days of cough, headache, nasal congestion and sore throat, though the zinc group also reported more nausea and bad-taste side effects.
Human RCT (n=100, adults)A Cochrane review of over 11,000 participants found regular vitamin C modestly shortens colds in adults, and more so under physical stress
Pooling 29 trial comparisons on cold incidence and 31 on cold duration, this Cochrane review found regular vitamin C supplementation did not reduce the risk of catching a cold in the general population, but reduced cold duration by 8 percent in adults; in a subgroup of marathon runners, skiers and soldiers under brief extreme physical stress, vitamin C nearly halved the risk of catching a cold (RR 0.48).
Systematic review and meta-analysis (Cochrane, n=11,306)A 2023 meta-analysis found regular vitamin C reduces how severe a cold feels, not just how long it lasts
Pooling 15 comparisons from 10 randomized, double-blind, placebo-controlled trials of at least 1 gram per day of vitamin C, this analysis found vitamin C significantly decreased overall cold severity by 15 percent, with a clearer benefit on the duration of the more severe stages of a cold than on milder symptoms.
Meta-analysisA reanalysis of an influential negative 1975 review found its own numbers actually showed a real benefit for vitamin C
This paper re-examined the seven placebo-controlled studies behind a widely cited 1975 review that concluded vitamin C had no effect on the common cold, and found that review had excluded relevant dosing information and used data inconsistent with the original publications; recalculating with the original studies' own data, the authors found vitamin C (1 to 6 g/day) reduced cold duration by 21 percent, illustrating how methodology choices can reverse a conclusion.
Reanalysis of controlled trialsTwo placebo-controlled trials of a combined vitamin C plus zinc formula found faster relief from cold symptoms
Reviewing the separate evidence for vitamin C and zinc against the common cold, this paper also presents two double-blind, randomized, placebo-controlled trials of a combined 1,000 mg vitamin C plus 10 mg zinc formula in cold patients; pooled analysis of both trials (n=94) found the combination significantly reduced rhinorrhoea duration over 5 days of treatment compared with placebo, with quicker symptom relief and good tolerability.
2 pooled human RCTs (n=94)A widely cited review explains the complementary immune mechanisms behind pairing vitamin C with zinc
Reviewing the immune-enhancing roles of vitamin C and zinc, this paper describes how vitamin C supports antimicrobial and natural killer cell activity and protects cells from oxidative damage during infection, while zinc deficiency impairs phagocytosis and natural killer cell activity - concluding that adequate intake of both nutrients ameliorates symptoms and shortens the duration of respiratory tract infections, including the common cold.
ReviewA review of 82 studies lays out practical adult dosing guidance for vitamin C and zinc against the common cold
Reviewing 82 studies on nutrients and the common cold, this review reports that regular vitamin C supplementation (1 to 2 g/day) reduces cold duration by 8 percent in adults, while zinc supplementation may shorten cold duration by approximately 33 percent when started within 24 hours of symptom onset, and recommends patients be encouraged to try these nutrients for prevention or treatment.
Review (82 studies)A foundational review explains how vitamin C supports both the innate and adaptive immune system
This widely cited review describes how vitamin C accumulates in neutrophils and enhances their chemotaxis, phagocytosis and microbial killing, supports epithelial barrier function against pathogens, and promotes the differentiation and proliferation of B- and T-cells - concluding that vitamin C deficiency impairs immunity and increases susceptibility to infection.
ReviewA systematic review of controlled trials found vitamin C measurably improved neutrophil function in several human studies
Reviewing 16 randomized controlled trials assessing vitamin C's effect on neutrophil chemotaxis, phagocytosis and oxidative burst, this review found that 44 percent of the trials showed a measurable benefit of vitamin C supplementation on at least one neutrophil function, most consistently in hospitalized patients or those under physical stress.
Systematic reviewA 2024 review of micronutrients in aging immunity highlights vitamin C alongside zinc, vitamin D and selenium
This review of vitamins A, D, E and C plus zinc and selenium as immunomodulators in the aging population describes how micronutrient deficiencies increase chronic low-grade inflammation and impair immune resilience, and discusses targeted nutritional supplementation as a potential way to help support healthy immune aging.
ReviewA review describes zinc as a 'gatekeeper' regulating immune cell signaling at the molecular level
This review describes how zinc ions regulate intracellular signaling pathways in both innate and adaptive immune cells via zinc importer and exporter proteins, with documented anti-inflammatory and antioxidant properties - concluding that zinc deficiency promotes a pro-inflammatory phenotype and that supplementation can benefit a malfunctioning immune system.
ReviewA 2024 review details zinc's specific roles across T cell development, activation and differentiation
Summarizing the roles of eight essential trace elements in T cell biology, this review describes zinc as necessary for T cell development in the thymus and for the proper activation and differentiation of helper and cytotoxic T cell subsets that defend against pathogens and tumours.
ReviewZinc supplementation trials in older adults found roughly two-thirds fewer infections
Reviewing his own and others' zinc supplementation trials in the elderly, the author reports that zinc supplementation decreased the incidence of infections by approximately 66 percent in the zinc group, alongside decreased oxidative stress biomarkers and decreased generation of inflammatory cytokines.
ReviewA controlled trial found zinc citrate - the exact form used in this formula - is absorbed as well as zinc gluconate and better than zinc oxide
Using a double-isotope tracer method in 15 healthy adults given 10 mg of zinc without food, this randomized, double-masked, three-way crossover trial found fractional absorption from zinc citrate (61.3 percent) was not different from zinc gluconate (60.9 percent) and was significantly higher than from zinc oxide (49.9 percent), concluding zinc citrate is a well-absorbed option for preventing zinc deficiency.
Human RCT / crossover trial (n=15)A 2024 narrative review comparing zinc forms found citrate performs comparably to other well-absorbed salts
Reviewing clinical studies that directly compare the absorption and bioavailability of different chemical forms of supplemental zinc in humans, this review notes that 17 to 20 percent of the global population may be at risk of zinc deficiency and reports that zinc glycinate and zinc gluconate were the best-absorbed forms studied, with zinc citrate performing comparably in head-to-head trials.
Narrative review / comparative studyA Cochrane review's own dosing data show why a moderate once-daily capsule differs from the high-dose lozenge regimens most commonly studied
In the same 2024 Cochrane review of zinc for the common cold, the most-studied treatment protocols used considerably higher, more frequent doses - zinc gluconate lozenges were typically given at 45 to 276 mg per day for up to three weeks - and were associated with a probable increase in non-serious adverse events such as bad taste and nausea; a well-absorbed zinc salt taken once daily, as in this formula, follows a different dosing pattern than those therapeutic lozenge regimens.
Systematic review and meta-analysis (Cochrane)A large cross-sectional study found women with higher dietary vitamin C intake had measurably less wrinkling and skin dryness
Examining diet and clinically assessed skin aging in 4,025 American women aged 40 to 74, this study found higher vitamin C intake was independently associated with a lower likelihood of a wrinkled appearance and senile dryness, after accounting for age, sun exposure, and other factors - one of the few studies to directly link dietary (not topical) vitamin C intake to observable skin-aging measures.
Cross-sectional cohort study (n=4,025 women)A dermatology review describes vitamin C's core biological mechanism as a required cofactor for collagen synthesis in skin
This review of vitamin C's mechanisms in skin describes it as one of the most powerful antioxidants in skin, noting an antiaging effect through increased collagen synthesis, stabilized collagen fibers and decreased collagen degradation, while protecting against oxidative damage from environmental stressors; most of the clinical evidence in this particular review concerns topical vitamin C formulations rather than oral supplementation.
ReviewA 2025 review of antioxidants for skin health highlights vitamin C's collagen-synthesis and photoprotective roles
Reviewing the contributions of key antioxidants to skin health, including vitamin C, vitamin E, vitamin A, green tea extract, coenzyme Q10, resveratrol, selenium and polyphenols, this review describes vitamin C as known for its collagen synthesis promotion and photoprotection properties, working synergistically with vitamin E to neutralize free radicals and repair damaged skin cells.
ReviewA classic JAMA report first linked excess zinc intake to a reversible form of anemia and bone marrow depression in adults
Describing two adult patients with sideroblastic anemia traced to zinc-induced copper deficiency - one from a zinc supplement, one from swallowed coins - this report found the anemia and bone marrow changes fully reversed once the excess zinc source was removed, establishing zinc-induced copper deficiency as a recognizable and reversible clinical entity.
Case series (adults)A Canadian case report describes zinc-induced copper deficiency as an under-recognized cause of anemia in a young adult
Reporting a case of reversible cytopenias (anemia and low white blood cell counts) in a young adult linked to excessive zinc intake from over-the-counter supplements, the authors highlight zinc-induced copper deficiency as an under-recognized cause that clinicians should consider when investigating unexplained blood count abnormalities.
Case reportA 2025 case report shows zinc-induced copper deficiency can still mimic a serious blood disorder today
Describing a 68-year-old man whose zinc supplement use (compounded by zinc-containing denture adhesive) led to copper deficiency that mimicked myelodysplastic syndrome on initial workup, the authors emphasize that clinicians should consider zinc-induced copper deficiency whenever investigating unexplained low blood counts, particularly given how common zinc supplementation has become.
Case reportFrequently asked questions
What is Orange Naturals Zinc + Vitamin C and what does it do?
It's a vegan capsule providing 50 mg Zinc (zinc citrate) and 400 mg Vitamin C (ascorbic acid) per capsule. It helps to maintain immune function.
How do I take it?
Adults (19 years and older) take 1 capsule per day with food, a few hours before or after taking other medications or natural health products.
What form of zinc does it use, and why?
It uses zinc citrate, a zinc salt shown in human research to be as well absorbed as zinc gluconate and better absorbed than zinc oxide.
Why does this product carry a copper caution?
Zinc supplementation can cause a copper deficiency. If you are unsure whether you are taking enough copper, ask a healthcare practitioner prior to use.
What are the medicinal ingredients?
Each vegan capsule contains Vitamin C (ascorbic acid) 400 mg and Zinc (zinc citrate) 50 mg.
How long does one bottle last?
Each bottle contains 90 vegan capsules - a 90-day supply at the standard dose of 1 capsule per day.
Is it vegan and allergen-friendly?
The label states this product is vegan and GMO-free, with no artificial flavours, colours, preservatives or sweeteners, and free from dairy, soy, gluten, wheat and yeast.
Is this the same as Orange Naturals' Kids Zinc + C Chewables?
No - this is a separate, adult-dosed product with its own Health Canada licence. It is formulated for adults (19 years and older) as a vegan capsule using a different zinc form and a higher zinc and vitamin C dose per serving, while the children's version is a lower-dose chewable tablet with pediatric-specific directions for ages 4 to 18.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Help support your immune function with Zinc + Vitamin C
Get Orange Naturals Zinc + Vitamin C on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80075970. Helps to maintain immune function. Consult a healthcare practitioner prior to use if you are unsure whether you are getting enough copper, as zinc supplementation can cause a copper deficiency. The research summaries on this page concern the individual ingredients generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Zinc supplementation can cause copper deficiency. Keep out of reach of children. Do not use if safety seal is broken.
Indications
Recommended Use or Purpose: Helps to maintain immune function.
Ingredients
Medicinal Ingredients (each capsule contains): Vitamin C (ascorbic acid), 400 mg. Zinc (zinc citrate), 50 mg. Non-medicinal Ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose.
Directions
Recommended Dose: Adults (19 years and older) - Take 1 capsule per day with food. Take a few hours before or after taking other medications.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.