Orange Naturals Vitamin D3 Drops 1000IU | 15mL, 450-Day Supply
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 drop daily (ages 0 and older) |
| Licensed Natural Health Product | NPN 80033265 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 1000 IU VITAMIN D3 PER DROP: Each drop provides 1000 IU (25 mcg) of Vitamin D3 (cholecalciferol), suspended in MCT oil - one of the higher-potency single-drop doses in the Orange Naturals D3 lineup.
- HELPS DEVELOP & MAINTAIN BONES AND TEETH: Helps in the development and maintenance of bones. Helps in the development and maintenance of teeth - this product's Health Canada-authorized use.
- MCT OIL FOR ABSORPTION: Suspended in medium chain triglycerides (MCT oil, from coconut) to help support the uptake of this fat-soluble vitamin versus a dry tablet.
- SIMPLE ONE-DROP DAILY DOSE FOR THE WHOLE FAMILY: Children, adolescents and adults (ages 0 and older): take 1 drop daily, added to food or drink, or straight on the tongue - no pills to swallow.
- NATURAL ORANGE FLAVOUR, EASY DROPPER FORMAT: A pleasant-tasting liquid format the whole family can use, with an easy-to-use dropper for a consistent daily dose.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals, developed by naturopathic doctors, and licensed under NPN 80033265. Ask a healthcare practitioner before use if you take medication or have a medical condition. Allergens: soy.
Product Description
Vitamin D3 Drops 1000IU - One Drop, Once a Day, for the Whole Family
Orange Naturals Vitamin D3 Drops 1000IU deliver 1000 IU (25 mcg) of Vitamin D3 (cholecalciferol) in every drop, suspended in MCT oil for easy daily dosing. Developed by naturopathic doctors, this natural orange-flavoured liquid helps in the development and maintenance of bones and teeth. Children, adolescents and adults (ages 0 and older) take just 1 drop daily - added to food or drink, or straight on the tongue. Ask a healthcare practitioner prior to use if you are taking any medication or have a medical condition. Allergens: soy - see the full cautions below. Licensed Natural Health Product NPN 80033265.
Les Gouttes de Vitamine D3 1000UI d'Orange Naturals offrent 1000 UI (25 mcg) de vitamine D3 (cholécalciférol) dans chaque goutte, en suspension dans une huile TCM (triglycérides à chaîne moyenne) pour un dosage facile. Développées par des médecins naturopathes, cette formule liquide au goût naturel d'orange aide au développement et au maintien des os et des dents. Les enfants, adolescents et adultes (dès la naissance) prennent seulement 1 goutte par jour - ajoutée à un aliment ou une boisson, ou directement sur la langue. Consulter un praticien de soins de santé avant l'usage si vous prenez des médicaments ou souffrez d'un état médical. Allergènes : soya - voir les mises en garde complètes ci-dessous. NPN 80033265.
A Higher-Potency, Single-Ingredient Vitamin D3 for Every Age
1000 IU Vitamin D3 per drop, in MCT oil - one drop daily, for ages 0 and up
1000 IU Vitamin D3 per Drop
Each drop delivers a precise 1000 IU (25 mcg) dose of Vitamin D3 (cholecalciferol) - children, adolescents and adults (ages 0 and older) take 1 drop daily.
MCT Oil Base for Absorption
Suspended in medium chain triglycerides (MCT oil, from coconut), supporting the uptake of this fat-soluble vitamin versus a dry tablet.
Advanced Ingredients, Superior Results
Vitamin D3 is one of the most-studied nutrients for bone and tooth development across every age group, and its role in immune function and muscle performance is an active area of ongoing research. Here is what the wider research explores.
Vitamin D3 (cholecalciferol)
The active form of vitamin D your body makes from sunlight - supports the development and maintenance of strong bones and teeth.
1000 IU (25 mcg) per drop
Orange Naturals Vitamin D3 Drops 1000IU: Supplement Facts
Each drop contains:
- Vitamin D3 (cholecalciferol)1000 IU (25 mcg)
Non-Medicinal Ingredients: Non-medicinal ingredients: D-alpha-tocopherol (soy), medium chain triglycerides (from coconut), orange flavour.
Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.
Recommended Dose (Children, Adolescents and Adults, ages 0 and older): Take 1 drop daily.
Cautions and Warnings: Ask a healthcare practitioner prior to use if you are taking any medication or you have a medical condition. Allergens: Soy. Do not use if the safety seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque goutte contient :
- Vitamine D3 (cholécalciférol)1000 IU (25 mcg)
Ingrédients non médicinaux : Ingrédients non médicinaux : D-alpha-tocophérol (soya), triglycérides à chaîne moyenne (provenant de noix de coco), arôme d'orange.
Usage ou fins recommandés : Aide au développement et au maintien des os et des dents.
Posologie recommandée (Enfants, adolescents et adultes, dès 0 an) : Prendre 1 goutte par jour.
Mises en garde : Consulter un praticien de soins de santé avant l'usage si vous prenez des médicaments ou vous souffrez d'un état médical. Allergènes : Soya. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.
NPN 80033265
Support strong bones and healthy teeth with Vitamin D3 Drops 1000IU
Get Orange Naturals Vitamin D3 Drops 1000IU on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Vitamin D3 Drops 1000IU
1000 IU Vitamin D3 per drop, in MCT oil - a simple one-drop daily dose for the whole family, ages 0 and up.
1000 IU D3 per drop
Each drop delivers a precise 1000 IU (25 mcg) dose of Vitamin D3 (cholecalciferol) - a higher-potency single-drop option.
Helps develop and maintain bones and teeth
Helps in the development and maintenance of bones. Helps in the development and maintenance of teeth - this product's Health Canada-authorized use.
Easy 1-drop daily dose, any age
Add to food or drink, or take straight on the tongue - no pills to swallow, natural orange flavour, for ages 0 and up.
Simple, single-ingredient formula
Just Vitamin D3 in MCT oil with natural orange flavour, made in Canada. Allergens: soy. NPN 80033265.
Inside every drop
1000 IU Vitamin D3 (cholecalciferol) suspended in MCT oil - children, adolescents and adults (ages 0 and older) take 1 drop daily. Ask a healthcare practitioner prior to use if you are taking any medication or have a medical condition. Allergens: soy.
How to use it
Take 1 drop daily
Children, adolescents and adults (ages 0 and older): take 1 drop daily, added to food or drink, or straight on the tongue.
A 450-day supply per bottle
Each 15 mL bottle provides approximately a 450-day supply at the standard 1-drop daily dose.
Use the dropper for a precise daily serving
The easy-to-use dropper helps ensure a consistent, hassle-free dose every day.
Read the cautions before you start
Ask a healthcare practitioner prior to use if you are taking any medication or have a medical condition. Allergens: soy. Do not use if the safety seal is broken.
What the research says about Vitamin D3
Educational summaries of published research on vitamin D3 generally; not product-specific claims. Orange Naturals Vitamin D3 Drops 1000IU's own authorized use under NPN 80033265 is that it helps in the development and maintenance of bones and teeth.
A dose-response trial found vitamin D3 increases calcium absorption with no plateau across a wide dose range
In a placebo-controlled trial of 76 healthy postmenopausal women given 800, 2000 or 4000 IU of vitamin D3 daily for 8 weeks, calcium absorption increased in a statistically significant linear trend with dose, with a 6.7% absolute increase in the highest-dose group and no evidence the effect levels off across the tested range.
Human RCT (n=76)A year-long trial found high-dose vitamin D3 modestly raised calcium absorption but did not improve bone density, muscle mass or falls versus placebo - an honest mixed result
In 230 postmenopausal women with vitamin D insufficiency randomized to placebo, low-dose (800 IU/day) or high-dose (50,000 IU twice monthly) vitamin D3 for one year, the high-dose group showed a small increase in calcium absorption, but no group showed differences in bone mineral density, muscle mass, physical performance tests, or number of falls.
Human RCT (n=230)A major systematic review of 69 trials in over 150,000 adults found little to no effect of vitamin D, calcium, or both on fractures or falls - a large, honest null result
Pooling 69 randomized trials totaling 153,902 adults, vitamin D supplementation alone (36 trials, 92,045 participants) showed little to no effect on the risk of any fracture, and combined calcium-plus-vitamin-D supplementation showed only a small effect that did not meet the review's threshold for clinical importance - findings that held up across extensive subgroup analyses.
Systematic review & meta-analysis (69 RCTs, n=153,902)A meta-analysis of 7 trials in nearly 72,000 older adults found vitamin D supplementation did not reduce overall fracture incidence, and may raise hip-fracture risk in women
Reviewing 7 randomized trials totaling 71,899 adults aged 60 and older without known bone disease, vitamin D supplementation showed no significant difference in total fracture incidence versus placebo, though women given vitamin D had a significantly higher rate of hip fractures than those on placebo - a caution-worthy, non-obvious finding.
Meta-analysis (7 RCTs, n=71,899)A year-long dose-ranging trial in postmenopausal women found calcium absorption tracks more closely with blood vitamin D levels than with the supplement dose itself
In 163 postmenopausal women with vitamin D insufficiency randomized to doses from 400 to 4800 IU/day of vitamin D3 for one year, calcium absorption correlated more strongly with achieved serum 25-hydroxyvitamin D levels than with the assigned dose, and the added calcium absorbed at the highest doses was modest - roughly what half a glass of milk would provide.
Human RCT (n=163)A trial in adults with chronic spinal cord injury found 12 months of vitamin D3 supplementation had no effect on bone mineral density at any measured site - an honest null result
In 42 adults living with chronic spinal cord injury and insufficient vitamin D status, randomized to medium-dose or high-dose vitamin D3 for 12 months, bone mineral density at the radius, femoral neck, distal femur and proximal tibia showed no improvement in either group compared with baseline, despite roughly a third of participants reaching sufficient vitamin D levels.
Human RCT (n=42)A national Canadian survey found vitamin D supplement users are far more likely to meet their needs than non-users, across every age group
Analyzing 2015 Canadian Community Health Survey - Nutrition data on 19,567 people aged 1 and older, the proportion falling below the estimated average vitamin D requirement was 85.2% or higher among non-supplement users across all age-sex groups, compared with as low as 7.9% among supplement users depending on age and sex.
National dietary intake survey (Canada, n=19,567)A large Canadian Health Measures Survey found about 1 in 5 people, including children, have inadequate vitamin D status - with age, weight and ethnicity as key risk factors
Measuring blood vitamin D levels in 21,770 Canadians aged 3 to 79 across multiple survey cycles, 19.0% had inadequate vitamin D status and 8.4% were at risk of deficiency, with younger adults, higher body mass index, lower household income, and several self-reported racialized groups (Black, East/Southeast Asian, Middle Eastern, South Asian) all independently associated with higher risk than the reference groups.
National health survey (Canada, n=21,770)A Canadian Health Measures Survey study found first-generation immigrants have lower vitamin D status than native-born Canadians, with ethnicity as the strongest predictor
In 11,579 participants of the Canadian Health Measures Survey, first-generation immigrants had significantly lower mean serum vitamin D than non-immigrants (51.2 vs 62.7 nmol/L), with younger age at immigration and several ethnic groups (notably Japanese, Arab and Southeast Asian) showing the highest deficiency rates, independent of how long they had lived in Canada.
National health survey (Canada, n=11,579)A nutrition-policy analysis argues that a daily intake in the range of this product's own 1000 IU dose is a safe, conservative guidance level for lifelong use
Reviewing the evidence behind national tolerable-upper-intake and guidance levels for vitamin D, the author notes that the United Kingdom's own guidance level - 1000 IU/day, defined as a dose safe for potentially susceptible individuals to take daily, lifelong, without medical supervision - sits well within the range shown not to raise blood vitamin D to concerning levels.
Nutrition policy analysisA large 3-year trial found 4000 IU/day of vitamin D3 - four times this product's own dose - was safe and well tolerated, with fewer adverse events than placebo
In 2,423 adults at high risk for type 2 diabetes randomized to 4000 IU/day of vitamin D3 or placebo for a median of 2.5 years, the vitamin D group had significantly fewer total adverse events than placebo, and there was no significant difference in serious adverse events, hypercalcemia, hypercalciuria, or kidney stones between groups.
Human RCT safety analysis (n=2,423)A meta-analysis found long-term daily doses of 3200-4000 IU - well above this product's 1000 IU dose - carry a small but real increased risk of hypercalcemia, falls and hospitalization
Pooling 22 randomized trials totaling 12,952 participants using 3200-4000 IU/day of vitamin D for 6 months or longer, the vitamin D group had a significantly higher relative risk of hypercalcemia (about 4 extra cases per 1000 people), falls, and hospitalization than placebo - a real, if uncommon, safety signal specifically at these higher long-term doses.
Systematic review & meta-analysis (22 RCTs, n=12,952)A meta-analysis of over 41,000 older adults found vitamin D supplementation probably does not reduce acute respiratory infections overall
Pooling 12 randomized trials totaling 41,552 older adults, vitamin D supplementation showed little to no effect on the incidence of acute respiratory infections compared with placebo, though a possible, not statistically significant, benefit was seen in the subgroup with the lowest baseline vitamin D levels.
Systematic review & meta-analysis (12 RCTs, n=41,552)A meta-analysis of over 200,000 people found vitamin D supplementation was associated with lower risk of severe COVID-19 disease and mortality
Reviewing 38 eligible studies including over 205,000 people with known vitamin D status, supplementation was associated with a significantly lower risk of both severe COVID-19 disease and mortality, with a greater mortality-risk reduction seen in older individuals and at higher latitudes.
Systematic review & meta-analysis (38 studies)A meta-analysis found vitamin D reduced ICU admissions and intubation in COVID-19 randomized trials, but a mortality benefit appeared only in non-randomized studies
Analyzing 29 studies on vitamin D supplementation in COVID-19 patients, randomized trials showed significantly reduced ICU admissions and intubation rates with vitamin D, but a significant mortality reduction was seen only in non-randomized analytical studies, not in the pooled randomized trials themselves - a nuanced, not clear-cut, overall picture.
Systematic review & meta-analysis (29 studies, 21 RCTs)A 2-year ancillary study of the VITAL trial found daily vitamin D3 supplementation did not improve physical performance in generally healthy older adults - an honest null result
In 1,054 adults (men 50+, women 55+) followed for 2 years as part of the VITAL trial, 2000 IU/day of vitamin D3 produced no significant difference in grip strength, walking speed, standing balance, chair-stand tests, or the Timed-Up-and-Go test compared with placebo.
Human RCT ancillary study (n=1,054)A study of South Asian women 60 and older found vitamin D sufficiency was linked to better lower-body function, but not grip strength
In 120 community-dwelling South Asian women aged 60 and older in the UK, those with sufficient vitamin D status performed significantly better on chair-stand and balance tests than those with deficiency or inadequacy, though no difference was found in handgrip strength or the Timed-Up-and-Go test.
Cross-sectional observational study (n=120)A trial in patients with COPD found a combined whey protein and vitamin D supplement improved grip strength and gait speed over 16 weeks - a combined-nutrient finding, not vitamin D alone
In patients with chronic obstructive pulmonary disease randomized to a combined whey-protein-and-vitamin-D supplement or placebo for 16 weeks, the supplemented group showed significant improvements in handgrip strength, gait speed and overall physical performance scores, alongside reduced inflammation markers - though the intervention combined vitamin D with protein rather than testing vitamin D alone.
Human RCT (n=163 COPD patients + 75 controls)A trial found vitamin D3 already dissolved in an oily solution absorbed equally well whether taken fasting or with a high-fat meal
In 88 adults randomized to a single 50,000 IU dose of vitamin D3 taken fasting or with a standardized high-fat breakfast, 25-hydroxyvitamin D levels rose significantly and similarly in both conditions, indicating that once vitamin D3 is solubilized in an oily vehicle like MCT oil, meal timing does not meaningfully change its uptake.
Human RCT, cross-over (n=88)An animal-model study found dissolving a vitamin D-class compound in medium- or long-chain triglyceride oil roughly doubled its oral bioavailability versus a non-lipid formulation
Studying seocalcitol - a vitamin D-analogue compound used in pharmaceutical research, not the cholecalciferol used in this product - dissolved in either medium-chain (MCT) or long-chain triglyceride oil, both lipid-based formulations produced about twice the oral bioavailability in rats compared with a non-lipid reference formulation, illustrating the general principle that fat-soluble vitamin D compounds benefit from an oil-based carrier.
Preclinical study (in vitro + rat model)A follow-up formulation study found simple MCT oil solutions were chemically more stable than more complex emulsifying delivery systems for the same vitamin D-class compound
Comparing simple medium- and long-chain triglyceride oil solutions against more complex self-microemulsifying drug delivery systems for the same vitamin D-analogue compound (seocalcitol, not cholecalciferol), the simple oil solutions showed comparable bioavailability and notably better chemical stability after accelerated storage testing than the more complex formulations.
Preclinical formulation studyThe largest vitamin D trial to date, in nearly 26,000 adults, found no reduction in cancer or major cardiovascular events - a landmark honest null result
In the VITAL trial of 25,871 US adults (men 50+, women 55+) randomized to 2000 IU/day of vitamin D3 or placebo for a median of 5.3 years, vitamin D was not associated with a lower risk of invasive cancer or major cardiovascular events (myocardial infarction, stroke, or cardiovascular death), and there was no excess risk of hypercalcemia or other adverse events.
Human RCT (n=25,871)A large trial in adults with prediabetes found high-dose vitamin D3 did not significantly lower the risk of developing type 2 diabetes
In the D2d trial of 2,423 adults with prediabetes randomized to 4000 IU/day of vitamin D3 or placebo, new-onset diabetes occurred in 293 vitamin D participants versus 323 on placebo (hazard ratio 0.88, not statistically significant), with a safety profile comparable between groups.
Human RCT (n=2,423)A trial in adults with Crohn's disease found high-dose vitamin D3 significantly raised blood vitamin D levels and improved mood scores versus the standard 1000 IU dose
In adults with Crohn's disease in remission randomized to 10,000 IU/day or 1,000 IU/day of vitamin D3 for 12 months, the higher dose significantly raised serum 25-hydroxyvitamin D levels, and both groups showed improved anxiety and depression scores over the study, with a good safety profile in both arms.
Human RCT, pilot (n=34)Frequently asked questions
What is Orange Naturals Vitamin D3 Drops 1000IU and what does it do?
It's a liquid drop supplement providing 1000 IU (25 mcg) of Vitamin D3 (cholecalciferol) per drop, suspended in MCT oil. It helps in the development and maintenance of bones and teeth.
Who can take it?
Children, adolescents and adults (ages 0 and older) take 1 drop daily, added to food or drink, or straight on the tongue.
Why is it suspended in MCT oil?
Vitamin D3 is a fat-soluble nutrient, so it is suspended in medium chain triglycerides (MCT oil, from coconut) to support its absorption, rather than delivered as a dry tablet.
What allergens does it contain?
This product contains soy (from the D-alpha-tocopherol).
How long does one bottle last?
Each 15 mL bottle provides approximately a 450-day supply at the standard dose of 1 drop daily.
Is it flavoured?
Yes - it has a natural orange flavour designed to make daily use easy for the whole family.
Is this the same as Orange Naturals D3+K2 Drops or Kids Vitamin D3 Drops?
No. This product contains only Vitamin D3 (1000 IU per drop, no Vitamin K2) and carries its own NPN (80033265). It is a higher-potency dose than the Kids Vitamin D3 Drops (400 IU per drop) and does not contain the Vitamin K2 found in the D3+K2 Drops (250 IU D3 + 30 mcg K2 per drop, adult 4-drop dosing) - each is a separately licensed product with its own dose and label.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Support strong bones and healthy teeth with Vitamin D3 Drops 1000IU
Get Orange Naturals Vitamin D3 Drops 1000IU on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80033265. Helps in the development and maintenance of bones. Helps in the development and maintenance of teeth. Ask a healthcare practitioner prior to use if you are taking any medication or have a medical condition. Allergens: soy. The research summaries on this page concern vitamin D3 generally, including some general research on immune function and muscle performance, and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Ask a healthcare practitioner prior to use if you are taking any medication or you have a medical condition. Allergens: Soy. Do not use if the safety seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.
Ingredients
Medicinal Ingredients (each drop contains): Vitamin D3 (cholecalciferol), 1000 IU (25 mcg). Non-medicinal Ingredients: D-alpha-tocopherol (soy), medium chain triglycerides (from coconut), orange flavour.
Directions
Recommended Dose (Children, Adolescents and Adults, ages 0 and older): Take 1 drop daily.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.