Orange Naturals Thyroid Spark - Ashwagandha & Iodine | NPN 80087041
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 2 capsules per day |
| Licensed Natural Health Product | NPN 80087041 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 7-ACTIVE THYROID FORMULA: Each 2-capsule serving delivers 450 mg L-Tyrosine, 100 mg Ashwagandha standardized to 1.5% withanolides, plus Zinc, Copper, Manganese, Iodine and Selenium.
- HELPS THYROID GLAND FUNCTION & PREVENTS IODINE DEFICIENCY: A factor in the maintenance of good health. Helps in the function of the thyroid gland. Helps to prevent iodine deficiency - this product's Health Canada-authorized use.
- STANDARDIZED ASHWAGANDHA & ALBION CHELATED MINERALS: Ashwagandha standardized to 1.5% withanolides, with Zinc, Copper and Manganese as Albion bisglycinate chelates and Selenium as an Albion glycinate complex for absorption.
- REAL CAUTIONS - READ BEFORE USE: Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer or follow a low-protein diet. Do not combine with alcohol or sedative medications or natural health products.
- VEGAN, NON-GMO, ALLERGEN-FREE: Vegan, GMO-free, and free of gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives and animal products.
- 60 VEGAN CAPSULES - 30-DAY SUPPLY: Adults (19 years and older): take 2 capsules per day, or as directed by a healthcare practitioner.
Product Description
Thyroid Spark - L-Tyrosine, Ashwagandha & 5 More Actives for Thyroid Support
Orange Naturals Thyroid Spark combines 450 mg L-Tyrosine with 100 mg Ashwagandha standardized to 1.5% withanolides, plus Zinc, Copper, Manganese, Iodine and Selenium in every 2-capsule serving. Developed by naturopathic doctors and made in Canada, this 7-active formula is a factor in the maintenance of good health, helps in the function of the thyroid gland, and helps to prevent iodine deficiency. This product also carries real, important cautions (including a caution for people with a history of non-melanoma skin cancer, and against combining with alcohol or sedative medications) - see below. NPN 80087041. Licensed Natural Health Product NPN 80087041.
Étincelle Thyroïde d'Orange Naturals combine 450 mg de L-Tyrosine et 100 mg d'Ashwagandha normalisé à 1,5% de withanolides, ainsi que du Zinc, du Cuivre, du Manganèse, de l'Iode et du Sélénium dans chaque portion de 2 capsules. Développée par des médecins naturopathes et fabriquée au Canada, cette formule à 7 ingrédients actifs est un facteur dans le maintien d'une bonne santé, aide au bon fonctionnement de la glande thyroïde et aide à prévenir une carence en iode. Ce produit comporte aussi de réelles mises en garde importantes, voir ci-dessous. NPN 80087041.
A Naturopathic-Developed 7-Active Thyroid Formula
450 mg L-Tyrosine + 100 mg standardized Ashwagandha, plus 5 more actives - simple once-daily dosing
450 mg L-Tyrosine + 100 mg Standardized Ashwagandha
Each 2-capsule serving delivers a full 450 mg dose of L-Tyrosine and 100 mg of Ashwagandha standardized to 1.5% withanolides, the two most prominent actives in this 7-active formula.
Developed by Naturopathic Doctors
Orange Naturals formulas, including Thyroid Spark, are developed by naturopathic doctors and made in Canada.
Advanced Ingredients, Superior Results
L-Tyrosine and iodine are the direct building blocks of thyroid hormone, and this formula also includes Ashwagandha, Zinc, Copper, Manganese and Selenium. Here is what the wider research explores about each.
L-Tyrosine
A non-essential amino acid and the direct chemical precursor to thyroid hormone (thyroxine) as well as the catecholamine neurotransmitters dopamine and norepinephrine.
450 mgAshwagandha (root, Withania somnifera) standardized to 1.5% withanolides
A traditional adaptogenic root extract, standardized to its withanolide content, studied for its effects on thyroid hormone indices and the body's stress response.
100 mgZinc (Albion zinc bisglycinate chelate)
A trace mineral cofactor involved in thyroid hormone metabolism, supplied here as a highly bioavailable chelated form.
7.5 mgCopper (Albion copper bisglycinate chelate)
An essential trace mineral paired with zinc in this formula at a balanced ratio, since high zinc intake alone can otherwise increase the body's need for copper.
1.5 mg
Manganese (Albion manganese bisglycinate chelate)
A trace mineral cofactor for antioxidant enzyme systems, supplied at a modest dose well within established safe dietary intake ranges.
500 mcgIodine (thallus, Laminaria digitata/Ascophyllum nodosum)
An essential mineral and direct building block of thyroid hormone, sourced from kelp (brown seaweed); required in the correct amount for normal thyroid hormone synthesis.
200 mcgSelenium (Albion selenium glycinate complex)
An essential trace mineral cofactor for thyroid hormone metabolism and antioxidant enzyme systems, studied both for thyroid support and for real safety considerations at higher doses.
100 mcgOrange Naturals Thyroid Spark: Supplement Facts
Each vegan capsule contains:
- L-Tyrosine450 mg
- Ashwagandha (root, Withania somnifera) standardized to 1.5% withanolides100 mg
- Zinc (Albion zinc bisglycinate chelate)7.5 mg
- Copper (Albion copper bisglycinate chelate)1.5 mg
- Manganese (Albion manganese bisglycinate chelate)500 mcg
- Iodine (thallus, Laminaria digitata/Ascophyllum nodosum)200 mcg
- Selenium (Albion selenium glycinate complex)100 mcg
Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose, magnesium stearate. Vegan. GMO free. No gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives or animal products.
Recommended Use or Purpose: A factor in the maintenance of good health. Helps in the function of the thyroid gland. Helps to prevent iodine deficiency.
Recommended Dose (Adults 19 years and older): Take 2 capsules per day, or as directed by a healthcare practitioner.
Cautions and Warnings: Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer, or if you are following a low protein diet. Consumption with alcohol or other medications or natural health products with sedative properties is not recommended. Do not use if seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque capsule végétale contient :
- L-Tyrosine450 mg
- Ashwagandha (racine, Withania somnifera) normalisé à 1,5% de withanolides100 mg
- Zinc (chélate de bisglycinate de zinc Albion)7.5 mg
- Cuivre (chélate de bisglycinate de cuivre Albion)1.5 mg
- Manganèse (chélate de bisglycinate de manganèse Albion)500 mcg
- Iode (thalle, Laminaria digitata/Ascophyllum nodosum)200 mcg
- Sélénium (complexe de glycinate de sélénium Albion)100 mcg
Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose, stéarate de magnésium. Convient aux végétaliens. Sans OGM. Sans gluten, produits laitiers, soya, blé, levure, sucre, colorants, arômes ou agents de conservation artificiels, ni produits d'origine animale.
Usage ou fins recommandés : Un facteur dans le maintien d'une bonne santé. Aide au bon fonctionnement de la glande thyroïde. Aide à prévenir une carence en iode.
Posologie recommandée (adultes de 19 ans et plus) : Prendre 2 capsules par jour, ou selon les directives d'un praticien de la santé.
Mises en garde : Consulter un praticien de soins de santé avant l'usage si vous avez des antécédents de cancer de la peau sans mélanome, ou si vous suivez une diète faible en protéine. Lorsque vous utilisez ce produit, la consommation de pair avec des breuvages alcoolisés ou tout autre médicament ou produit de santé naturel ayant des effets sédatifs est déconseillée. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.
NPN 80087041
Support healthy thyroid gland function with Thyroid Spark
Get Orange Naturals Thyroid Spark on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Thyroid Spark
A 7-active formula built around 450 mg L-Tyrosine and 100 mg standardized Ashwagandha (1.5% withanolides) - developed by naturopathic doctors, with real cautions you should read before use.
7 real actives, standardized where it matters
Ashwagandha standardized to 1.5% withanolides, alongside L-Tyrosine, Zinc, Copper, Manganese, Iodine and Selenium as Albion chelated minerals.
Helps thyroid gland function and prevents iodine deficiency
A factor in the maintenance of good health. Helps in the function of the thyroid gland. Helps to prevent iodine deficiency.
Simple once-daily dose
Adults (19 years and older): take 2 capsules per day, or as directed by a healthcare practitioner.
Real cautions, developed by naturopathic doctors
Formulated by Orange Naturals and developed by naturopathic doctors. Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer or follow a low-protein diet. NPN 80087041.
Inside every 2-capsule serving
450 mg L-Tyrosine and 100 mg Ashwagandha (standardized to 1.5% withanolides), plus Zinc, Copper, Manganese, Iodine and Selenium. Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer or follow a low-protein diet. Do not combine with alcohol or sedative medications/natural health products.
How to use it
Take 2 capsules daily
Adults (19 years and older): take 2 capsules per day, or as directed by a healthcare practitioner.
Avoid alcohol and sedatives while taking it
Consumption with alcohol or other medications or natural health products with sedative properties is not recommended.
A 30-day supply per bottle
Each bottle of 60 vegan capsules provides a 30-day supply at the standard 2-capsule daily dose.
Read the cautions before you start
Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer or follow a low-protein diet. Do not use if you are pregnant or breastfeeding.
What the research says about this formula's ingredients
Educational summaries of published research on L-Tyrosine, Ashwagandha, iodine, zinc, copper, manganese and selenium generally; not product-specific claims. Orange Naturals Thyroid Spark's own authorized use under NPN 80087041 is that it is a factor in the maintenance of good health, helps in the function of the thyroid gland, and helps to prevent iodine deficiency.
A cryo-EM structure revealed how thyroglobulin assembles iodinated tyrosine pairs into thyroid hormone
Using cryo-electron microscopy to resolve the structure of full-length human thyroglobulin, researchers identified the hormonogenic tyrosine pairs within the protein and verified them experimentally, showing that the proximity, flexibility and solvent exposure of these tyrosines are the key features enabling iodination and coupling into thyroid hormone.
Structural biology studyA separate cryo-EM structure captured nascent thyroid hormone forming inside native bovine thyroglobulin
Reporting a roughly 3.3-angstrom cryo-EM structure of native bovine thyroglobulin with nascent thyroid hormone formed at one of its predicted hormone-forming sites, this study revealed local structural rearrangements that help explain how the protein stabilizes newly formed thyroid hormone before it is released.
Structural biology studyA biochemical study identified the specific molecular feature that drives efficient thyroxine formation
Using an engineered single-site protein precursor, this study found that a conserved acidic residue (preferably glutamate) positioned near the hormone-forming tyrosine favors thyroxine synthesis by facilitating deprotonation during the iodination and coupling reaction - a mechanistic detail underlying how the body builds thyroid hormone from iodine and tyrosine.
Biochemical/computational studyA review outlined the consequences of both iodine deficiency and iodine excess in pregnant women
Summarizing current knowledge on iodine status in pregnancy, this review confirmed that severe iodine deficiency causes serious adverse effects including cretinism, while also noting that excessive iodine intake can alter thyroid function in susceptible individuals - concluding that safe upper limits for iodine intake in pregnancy remain poorly defined and warrant further research.
ReviewA population survey found excess iodine was a real, quantified risk factor for subclinical hypothyroidism
Surveying 1,859 adults in Chengdu with adequate median urinary iodine, this study found excess iodine intake was significantly associated with increased odds of subclinical hypothyroidism (odds ratio 1.50), while iodine deficiency was separately associated with a higher risk of multiple thyroid nodules - underscoring that both too little and too much iodine carry real, distinct risks.
Population survey (n=1,859)A systematic review and meta-analysis found insufficient evidence to support iodine supplementation recommendations in mild-to-moderate deficiency
Reviewing 37 publications on iodine supplementation in mildly-to-moderately iodine-deficient pregnant women, this review found most studies showed no effect on maternal or infant thyroid hormone levels, and concluded there is currently insufficient good-quality evidence to support current recommendations for iodine supplementation in this population - an honest, cautious conclusion calling for better-designed trials.
Systematic review and meta-analysisA secondary analysis of a nutrition-support trial found low tyrosine levels were linked to higher mortality in at-risk patients
In 238 medical inpatients at nutritional risk from the EFFORT randomized trial, low plasma tyrosine levels were associated with significantly increased 30-day and long-term mortality, and patients with higher tyrosine levels showed a more pronounced response to individualized nutritional support - consistent with tyrosine's role as the metabolic precursor of both thyroid hormones and catecholamines.
Human RCT secondary analysis (n=238)A review found tyrosine supplementation can counteract cognitive decrements during short-term stress or heavy cognitive demand
Reviewing available cognitive and behavioral studies on tyrosine, the review found its benefits for enhancing physical exercise or treating clinical disorders appear limited, but that tyrosine effectively enhances cognitive performance specifically in short-term stressful or cognitively demanding situations, likely by replenishing temporarily depleted dopamine and norepinephrine.
ReviewA systematic review found tyrosine loading counteracts working-memory decrements under demanding conditions but not exercise performance
Reviewing 15 studies on tyrosine's behavioral and cognitive effects in healthy adults, most behavioral (exercise) studies found no significant benefit, while cognitive studies found tyrosine loading acutely counteracted decrements in working memory and information processing induced by demanding conditions such as extreme cold or high cognitive load.
Systematic reviewA randomized trial found ashwagandha root extract normalized thyroid indices in subclinical hypothyroid patients
In 50 subjects with subclinical hypothyroidism (elevated TSH) randomized to 8 weeks of 600 mg/day ashwagandha root extract or placebo, treatment significantly improved serum TSH, T3 and T4 levels compared with placebo, effectively normalizing thyroid indices over the treatment period.
Human RCT (n=50)A safety trial in healthy adults found no significant change in thyroid hormone levels with ashwagandha supplementation
In 80 healthy adults randomized to 300 mg ashwagandha root extract or placebo twice daily for 8 weeks, primarily assessing safety, there was no statistically significant change or abnormality in thyroid function parameters or any other safety measure in either group, and no adverse events were reported.
Human RCT (n=80)A study in patients with bipolar disorder found subtle thyroid-index changes with ashwagandha, prompting a caution about vigilance for hyperthyroidism
Measuring thyroid function safety markers during an 8-week ashwagandha trial in patients with bipolar disorder, all three ashwagandha-treated patients showed increases in T4 from baseline (7-24%), in contrast to most placebo-assigned patients who showed T4 decreases - a subtle laboratory signal that led the authors to suggest vigilance regarding hyperthyroidism may be warranted with ashwagandha use, alongside its potential as a treatment avenue for subclinical hypothyroidism.
Human RCT sub-analysis (n=10 of 60 with abnormal indices)A meta-analysis of randomized trials found selenium supplementation reduced thyroid antibodies and modestly lowered TSH in Hashimoto's thyroiditis
Pooling 35 randomized controlled trials, this meta-analysis found selenium supplementation significantly decreased thyroid peroxidase antibodies (TPOAb) in patients without thyroid hormone replacement, and modestly reduced TSH after 6 months, with adverse effects comparable to placebo - rated moderate-certainty evidence.
Systematic review and meta-analysis (35 RCTs)A critical reappraisal concluded current evidence does not justify selenium supplementation for autoimmune thyroiditis, despite antibody reductions
Reappraising 23 trials in adults with chronic autoimmune thyroiditis, selenium supplementation lowered thyroid peroxidase and thyroglobulin antibody levels at several time points, but participants receiving selenium had a significantly HIGHER risk of reported adverse effects - leading the authors to an honest, cautious conclusion that current evidence does not yet justify its emerging clinical use.
Systematic review and meta-analysis (23 RCTs)A meta-analysis found selenomethionine was the most effective form of selenium for reducing thyroid antibodies in Hashimoto's thyroiditis
Analyzing 21 studies with 1,610 subjects, selenium supplementation significantly reduced thyroid peroxidase and thyroglobulin antibodies at 3 and 6 months, with selenomethionine outperforming sodium selenite and selenium yeast forms specifically for Hashimoto's thyroiditis.
Systematic review and meta-analysis (n=1,610)A landmark randomized trial found selenium supplementation significantly increased the risk of non-melanoma skin cancer
In the full follow-up of the Nutritional Prevention of Cancer Trial (1,312 patients with a history of skin cancer, 200 mcg/day selenized yeast for a mean 4.5 years), selenium supplementation was associated with a statistically significant increase in the risk of squamous cell carcinoma (hazard ratio 1.25) and total non-melanoma skin cancer (hazard ratio 1.17) - the real evidence base behind this product's own caution for people with a history of non-melanoma skin cancer.
Human RCT (n=1,312)The original Nutritional Prevention of Cancer Trial found selenium did not protect against skin cancer but reduced other cancer mortality
In this same 1,312-patient trial's earlier published analysis, selenium treatment did not significantly affect the incidence of basal or squamous cell skin cancer (its primary endpoint), but secondary analyses found significant reductions in total cancer mortality and total cancer incidence - a genuinely mixed result, later superseded by the longer follow-up's finding of increased skin cancer risk.
Human RCT (n=1,312)A review argued the safe upper intake level for selenium may need to be reassessed downward
Reviewing recent epidemiologic and molecular evidence, this review found adverse effects of selenium exposure at levels sometimes below or only slightly above intakes needed to maximize selenoprotein activity, and called for reassessing dietary reference values and upper intake levels for selenium in light of this newer evidence.
ReviewA randomized trial found zinc, magnesium and vitamin A co-supplementation improved thyroxine levels in hypothyroid patients
In 86 hypothyroid patients randomized to 10 weeks of daily zinc gluconate, magnesium oxide and vitamin A co-supplementation or placebo, the intervention group showed a significant increase in serum free thyroxine (FT4) and lower inflammatory markers (hs-CRP) compared with placebo.
Human RCT (n=86)A clinical study found zinc sulfate supplementation improved thyroid function in zinc-deficient children with Down syndrome
In children with Down syndrome who commonly show low plasma zinc, cyclic zinc sulfate supplementation over two 6-month cycles significantly lowered elevated TSH levels in the zinc-deficient subgroup, bringing thyroid function in line with normally-zinc children by the end of the study.
Clinical trialA systematic review found zinc and selenium supplementation effects on thyroid function in people with overweight or obesity remain inconsistent
Reviewing 13 randomized controlled trials of zinc and/or selenium supplementation in people with overweight or obesity, zinc supplementation was found to increase free T3 levels in one hypothyroid-patient study, but the overall evidence for zinc, selenium and their combination on thyroid function and body composition was rated inconsistent and limited, calling for caution in interpretation.
Systematic review (13 RCTs)A trace-element research review confirmed that high zinc intake increases the body's need for copper
Summarizing decades of human depletion/repletion research on essential trace elements, this review confirmed that zinc deficiency increases the physiological need for copper, and that high dietary zinc intake can exacerbate signs of copper deficiency - the reasoning behind pairing zinc with copper in a balanced ratio within a single formula.
ReviewA real case report described severe copper deficiency, mimicking a bone marrow disorder, from prolonged excess zinc exposure
An 83-year-old woman using zinc oxide denture paste developed macrocytic anemia and neutropenia that initially mimicked myelodysplastic syndrome; the true cause was identified as severe copper deficiency secondary to chronic excess zinc exposure, and her blood counts and symptoms markedly improved after copper supplementation and stopping the zinc source - a real, cautionary example of why zinc and copper intake should stay balanced.
Case reportA dietary exposure review found manganese intake at typical levels is not associated with adverse health effects
Assessing dietary manganese exposure in the general German adult population (about 2.8 mg/day), this review found intake fell within recommended ranges and identified no indication that these typical dietary levels are associated with adverse health effects from either manganese deficiency or excess, while noting a concentrated supplemental bolus dose could carry different risk considerations in certain subpopulations.
ReviewFrequently asked questions
What is Orange Naturals Thyroid Spark and what does it do?
It's a 7-active vegan capsule formula built around 450 mg L-Tyrosine and 100 mg Ashwagandha standardized to 1.5% withanolides, plus Zinc, Copper, Manganese, Iodine and Selenium. It is a factor in the maintenance of good health, helps in the function of the thyroid gland, and helps to prevent iodine deficiency.
How do I take it?
Adults (19 years and older) take 2 capsules per day, or as directed by a healthcare practitioner. Consumption with alcohol or other medications or natural health products with sedative properties is not recommended.
Why does this product have a caution about skin cancer?
One of this formula's actives is selenium. Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer, as printed on the real label and registered with Health Canada for this product.
Who should NOT use this product?
Do not use this product if you are pregnant or breastfeeding, as printed on the label.
Who should consult a healthcare practitioner before using it?
Consult a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer, or if you follow a low protein diet.
Does this product interact with anything?
Consumption with alcohol, other drugs, or natural health products with sedative properties is not recommended while taking this product.
How long does one bottle last?
Each bottle contains 60 vegan capsules - a 30-day supply at the standard dose of 2 capsules per day.
Is it vegan and allergen-friendly?
Yes - it is vegan, non-GMO, and free of gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives and animal products.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Support healthy thyroid gland function with Thyroid Spark
Get Orange Naturals Thyroid Spark on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80087041. A factor in the maintenance of good health. Helps in the function of the thyroid gland. Helps to prevent iodine deficiency. Do not use if you are pregnant or breastfeeding. Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer, or if you follow a low protein diet. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended. The research summaries on this page concern these ingredients generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Ask a healthcare practitioner prior to use if you have a history of non-melanoma skin cancer, or if you are following a low protein diet. Consumption with alcohol or other medications or natural health products with sedative properties is not recommended. Do not use if seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: A factor in the maintenance of good health. Helps in the function of the thyroid gland. Helps to prevent iodine deficiency.
Ingredients
Medicinal Ingredients (each vegan capsule contains): L-Tyrosine 450 mg. Ashwagandha (root, Withania somnifera) standardized to 1.5% withanolides, 100 mg. Zinc (Albion zinc bisglycinate chelate) 7.5 mg. Copper (Albion copper bisglycinate chelate) 1.5 mg. Manganese (Albion manganese bisglycinate chelate) 500 mcg. Iodine (thallus, Laminaria digitata/Ascophyllum nodosum) 200 mcg. Selenium (Albion selenium glycinate complex) 100 mcg. Non-medicinal Ingredients: Hypromellose, magnesium stearate. Vegan. GMO free. No gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives or animal products.
Directions
Recommended Dose (Adults 19 years and older): Take 2 capsules per day, or as directed by a healthcare practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.