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Health Canada NPN 80118843 30 mg Wheat Seed Extract Standardized to 50% Ceramides per Capsule Vegan · Made in Canada · Developed by Naturopathic Doctors Contains Wheat (Allergen) - Ask a Practitioner if Pregnant or Breastfeeding
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Orange Naturals Skin Bliss with Ceramides | 30 Capsules

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$28.99 CAD ($0.97 / capsule)
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BrandOrange
Serving1 capsule per day
Licensed Natural Health ProductNPN 80118843
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • PLANT-DERIVED CERAMIDES FROM WHEAT SEED: Each vegetable capsule provides 30 mg of a 667:1 wheat (Triticum aestivum) seed extract, standardized to 40% digalactosyl diglyceride and 50% ceramides - take 1 capsule per day.
  • HELPS REDUCE SKIN MICROWRINKLES AND INCREASE SKIN ELASTICITY: Skin Bliss helps to reduce skin microwrinkles and increase skin elasticity.
  • SIMPLE ONE-CAPSULE DAILY RITUAL: Adults (19 years and older): take 1 capsule per day.
  • CONTAINS WHEAT - READ BEFORE USE: This product's only medicinal ingredient is a wheat seed extract, and the real label declares wheat as an allergen. Ask a healthcare practitioner prior to use if you are pregnant or breastfeeding.
  • MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80118843. Developed by naturopathic doctors.

Customer Reviews

3.9 out of 5 · 9 global ratings
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Product Description

Skin Bliss with Ceramides - Plant-Derived Ceramides from Wheat Seed Extract

Orange Naturals Skin Bliss with Ceramides

Orange Naturals Skin Bliss delivers 30 mg of a 667:1 wheat (Triticum aestivum) seed extract in every vegetable capsule, standardized to 40% digalactosyl diglyceride and 50% ceramides. This formula helps to reduce skin microwrinkles and increase skin elasticity. This product's only medicinal ingredient is wheat-derived, and its real label declares wheat as an allergen - see below before use. Licensed Natural Health Product NPN 80118843.

Douceur cutanée avec Céramides d'Orange Naturals offre 30 mg d'un extrait de graine de blé (Triticum aestivum) 667:1 dans chaque capsule végétale, normalisé à 40% digalactosyl diglycéride et 50% céramides. Cette formule aide à réduire les microrides de la peau et à augmenter son élasticité. L'ingrédient médicinal de ce produit provient du blé, et son étiquette réelle déclare le blé comme allergène - voir ci-dessous avant l'usage. NPN 80118843.

Skin Bliss with Ceramides lifestyle
Orange Naturals Skin Bliss with Ceramides
30 mg Wheat-Derived Ceramides · 50% Standardized Extract

A Single-Active Ceramide Formula

30 mg of a 667:1 wheat seed extract, standardized to 50% ceramides - 1 capsule daily

30 mg Wheat Seed Extract (667:1), Standardized to 50% Ceramides

Each vegetable capsule delivers 30 mg of a 667:1 wheat (Triticum aestivum) seed extract, standardized to 40% digalactosyl diglyceride and 50% ceramides - take 1 capsule per day.

Helps Reduce Skin Microwrinkles and Increase Skin Elasticity

Skin Bliss helps to reduce skin microwrinkles and increase skin elasticity.

What's Inside Skin Bliss

Wheat-derived plant ceramides and glucosylceramides have been studied for their role in skin barrier function, hydration and skin aging - and this product's wheat-derived ingredient carries a real, labelled allergen caution. Here is what the wider research explores.

Plant-Derived Ceramides

Each capsule delivers 30 mg of a wheat seed extract standardized to 50% ceramides, supplying the same class of lipid found naturally in the skin's outer barrier.

Helps Reduce Skin Microwrinkles

Skin Bliss helps to reduce skin microwrinkles and increase skin elasticity.

One Capsule, Once a Day

Adults (19 years and older): take 1 capsule per day - a simple daily addition to your routine.

Contains Wheat - A Real, Labelled Caution

This product's only medicinal ingredient is a wheat-derived extract. The label declares wheat as an allergen, and pregnant or breastfeeding individuals should ask a healthcare practitioner before use.

Orange Naturals Skin Bliss with Ceramides: Supplement Facts

Orange™Skin Bliss with Ceramides
English

Each vegetable capsule contains:

  • Wheat (seed, Triticum aestivum) 667:1 extract equivalent to 20,000 mg of dry seed, standardized to 40% digalactosyl diglyceride and 50% ceramides30 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose.

Recommended Use or Purpose: Helps to reduce skin microwrinkles and increase skin elasticity.

Recommended Dose (Adults 19 years and older): Take 1 capsule per day.

Cautions and Warnings: Allergens: wheat. Ask a healthcare practitioner prior to use if you are pregnant or if you are breastfeeding. Keep out of reach of children. Do not use if the safety seal is broken.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

Français

Chaque capsule végétale contient :

  • Blé (graine, Triticum aestivum) extrait 667:1 équivalent à 20 000 mg de graine sèche, normalisé à 40% digalactosyl diglycéride et 50% céramides30 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose, stéarate de magnésium, cellulose microcristalline.

Usage ou fins recommandés : Aide à réduire les microrides de la peau et à augmenter son élasticité.

Posologie recommandée (adultes de 19 ans et plus) : Prendre 1 capsule par jour.

Mises en garde : Allergènes : blé. Consulter un praticien de soins de santé avant d'en faire l'usage si vous êtes enceinte ou si vous allaitez. Tenir hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.

NPN 80118843

30 mg Wheat Seed Extract, Standardized to 50% Ceramides, per Capsule30 Veg Capsules - 30-Day Supply at 1 Capsule per DayVegan · 1 Capsule Daily · Contains Wheat (Allergen)Ask a Healthcare Practitioner Before Use if Pregnant or Breastfeeding

Support your skin's own ceramides with Skin Bliss

Get Orange Naturals Skin Bliss with Ceramides on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why Orange Naturals Skin Bliss

30 mg of a wheat seed extract standardized to 50% ceramides in every capsule - with a real, labelled wheat allergen caution you should read before use.

30 mg Wheat-Derived Ceramide Extract per Capsule

Each vegetable capsule delivers a 667:1 wheat seed extract standardized to 40% digalactosyl diglyceride and 50% ceramides - the same class of lipid naturally found in the skin's outer barrier.

Helps reduce skin microwrinkles and increase skin elasticity

Skin Bliss helps to reduce skin microwrinkles and increase skin elasticity.

Simple once-daily capsule

Take 1 capsule per day - that's it.

A real, labelled wheat caution, made in Canada

This product's medicinal ingredient is wheat-derived, and the label declares wheat as an allergen. Ask a healthcare practitioner prior to use if you are pregnant or breastfeeding. NPN 80118843.

How to use it

Take 1 capsule daily

Adults (19 years and older): take 1 capsule per day.

A 30-day supply per bottle

Each bottle of 30 veg capsules provides a 30-day supply at the standard 1-capsule daily dose.

Read the wheat caution before you start

This product's only medicinal ingredient is a wheat seed extract, and the label declares wheat as an allergen - check with your healthcare practitioner if you have a wheat allergy.

Ask a practitioner if pregnant or breastfeeding

Ask a healthcare practitioner prior to use if you are pregnant or if you are breastfeeding.

What the research says about this formula's active

Educational summaries of published research on wheat-derived ceramides, plant glucosylceramide and skin barrier ceramides generally; not additional product-specific claims. Orange Naturals Skin Bliss's own authorized use under NPN 80118843 is that it helps reduce skin microwrinkles and increase skin elasticity. This product's only medicinal ingredient is a wheat seed extract, and its real label declares wheat as an allergen - see the safety research below.

Wheat & Plant-Derived Ceramides - Oral Supplementation (This Formula's Own Category)

A 12-week RCT found oral plant-derived ceramides and glucosylceramides significantly lowered transepidermal water loss

In a randomized, double-blind, placebo-controlled trial of 29 healthy adults, 12 weeks of oral wine lees extract-derived ceramides and glucosylceramides produced significantly lower transepidermal water loss (TEWL) than placebo, with no supplement-related adverse events reported - demonstrating that plant-derived ceramide and glucosylceramide compounds, the same class of actives in this formula, can measurably support skin barrier function when taken orally.

Human RCT (n=29)
Sanjaya et al., Nutrients (2024)
Wheat & Plant-Derived Ceramides - Oral Supplementation (This Formula's Own Category)

A 4-week crossover RCT of glucosylceramide, a compound also found in wheat, significantly reduced water loss and improved chapped skin

In a randomized, double-blind, crossover trial of 17 healthy adults, 4 weeks of oral glucosylceramide (a compound the authors note is present in foods including wheat flour) significantly lowered transepidermal water loss and significantly improved chapped skin and brown spots compared to placebo during winter months.

Human RCT (n=17, crossover)
Fukunaga et al., J Nutr Sci Vitaminol (2018)
Wheat & Plant-Derived Ceramides - Oral Supplementation (This Formula's Own Category)

An 8-week RCT of a glucosylceramide-containing beverage maintained cheek skin water content versus placebo

In a randomized, double-blind, placebo-controlled, parallel-group trial of 60 healthy adults concerned about skin dryness, 8 weeks of a glucosylceramide-containing rice-fermented beverage maintained cheek skin water content while the placebo group's water content declined, at a glucosylceramide dose in the same range shown in prior research to improve skin water content and water loss.

Human RCT (n=60)
Enomoto et al., Clin Cosmet Investig Dermatol (2022)
Plant-Derived Glucosylceramide - Skin Barrier Mechanism

An animal study found oral plant glucosylceramide prevented skin barrier breakdown and dryness

In hairless mice fed a diet that induces dry, barrier-impaired skin, supplementing with beet extract rich in glucosylceramide significantly prevented the increase in transepidermal water loss, scratching behaviour and epidermal thickening seen in unsupplemented animals, illustrating a mechanism by which dietary plant glucosylceramide can protect skin barrier function.

Preclinical study (animal model)
Kawano & Umemura, Phytother Res (2012)
Plant-Derived Glucosylceramide - Skin Barrier Mechanism

A review describes how dietary glucosylceramide and ceramide are absorbed, metabolized and support skin barrier function

Reviewing sphingolipids as functional food components, the author describes how dietary ceramide, glucosylceramide and related sphingolipids from plant, animal and fungal sources are digested, absorbed and metabolized, and summarizes the evidence for their role in improving skin barrier function, while noting further research is needed to fully define their mechanisms.

Review
Sugawara, J Agric Food Chem (2022)
Plant-Derived Glucosylceramide - Skin Barrier Mechanism

A review found dietary glucosylceramide improves skin disorders alongside intestinal benefits

Reviewing dietary sphingolipids, the authors describe how plant-derived glucosylceramide, despite being absorbed at a low overall ratio, contributes to improvements in intestinal impairments, lipid metabolism and skin disorders, distinguishing its structure and function from the sphingomyelin found in animal-derived foods.

Review
Yamashita et al., Int J Mol Sci (2021)
Dietary Plant Glucosylceramide - Intestinal Absorption (Mechanism)

A rat study traced how dietary plant glucosylceramide is absorbed into the lymph and incorporated into ceramide

Using lymph-duct-cannulated rats, researchers found that glucosylceramide from maize (a plant source structurally similar to the wheat-derived glucosylceramide in this formula) is absorbed from the intestine, in part, and incorporated into ceramide structures in intestinal cells, though the plant-type sphingoid base itself was only slightly absorbed intact.

Preclinical study (animal model)
Sugawara et al., J Lipid Res (2010)
Dietary Plant Glucosylceramide - Intestinal Absorption (Mechanism)

A rat study found a specific enzyme limits how much dietary plant glucosylceramide is absorbed intact

Investigating the intestinal absorption of maize-derived glucosylceramide's characteristic plant sphingoid base in rats, researchers found that a drug-transport protein (P-glycoprotein) actively limits its absorption, and that blocking this transporter significantly increased how much of the plant compound reached the lymph.

Preclinical study (animal model)
Fujii et al., J Nutr Sci Vitaminol (2017)
Dietary Plant Glucosylceramide - Intestinal Absorption (Mechanism)

A rat study found the chemical structure of a dietary sphingolipid's backbone determines how well it is absorbed

Comparing five structurally different plant- and shellfish-derived sphingoid bases in lymph-duct-cannulated rats, researchers found absorption percentages ranged more than tenfold (0.10% to 1.17%) depending on subtle differences in molecular structure, and that all forms were detected in the lymph as ceramides and related metabolites after oral dosing.

Preclinical study (animal model)
Mikami et al., Lipids Health Dis (2021)
Ceramides & the Skin's Barrier Structure (General Mechanism)

A review explains how ceramides form the water-barrier structure unique to skin

Reviewing the skin's lipid barrier, the author describes how differentiating skin cells generate ceramides found only in skin, which form specialized layered structures that create a tight, hydrophobic barrier protecting the body from water loss and from penetration by allergens and bacteria.

Review
Berdyshev, Allergy Asthma Immunol Res (2024)
Ceramides & the Skin's Barrier Structure (General Mechanism)

A review describes the digestion, absorption and skin-related roles of dietary sphingolipids like ceramide

Reviewing the nutritional functions of dietary sphingomyelin and related sphingolipids (including ceramide and its metabolites), the authors summarize their distribution across foods, their digestion and metabolic pathways, and their applications in functional foods aimed at skin improvement.

Review
Yang & Chen, Front Nutr (2022)
Ceramides & the Skin's Barrier Structure (General Mechanism)

A lab study found a ceramide-forming formulation reduced how much airborne pollution penetrated human skin

Using organ-cultured human skin, researchers found that toxic compounds from diesel particulate matter can permeate even barrier-competent skin, and that a topical formulation designed to form more uniform ceramide-based membrane structures significantly reduced this penetration - illustrating how a well-organized ceramide layer helps defend the skin barrier.

Laboratory study (ex vivo human skin)
Shin et al., Skin Pharmacol Physiol (2024)
Ceramide Decline & Skin Aging (Mechanism)

A classic study found total skin ceramide content declines significantly with age

Measuring ceramide content directly in stratum corneum samples from 65 healthy individuals, researchers found total ceramide content declined significantly with increasing age, in addition to finding a marked reduction in atopic dermatitis - identifying ceramide insufficiency as a factor in both aging and atopic dry skin.

Human study (n=65 healthy + 32-35 AD)
Imokawa et al., J Invest Dermatol (1991)
Ceramide Decline & Skin Aging (Mechanism)

A study in older adults found restoring the skin's acid balance increased its own ceramide levels

In older subjects with dry skin, 3 weeks of a pH 4.0 plant-oil skin care product increased lipid lamellae and ceramide levels in the stratum corneum, even though the product itself did not contain ceramides - showing that supporting the skin's own barrier conditions can help restore ceramide levels lost with age.

Human study (older adults with dry skin)
Blaak et al., Int J Cosmet Sci (2016)
Ceramide Decline & Skin Aging (Mechanism)

A cross-sectional study of 220 people found the skin's fatty-acid composition shifts with age

Comparing free fatty acids in the stratum corneum of 110 healthy adults over 60 and 110 healthy adults aged 18-40, researchers found several fatty acids that combine with sphingoid bases to form ceramides shifted in relative abundance with age, contributing to the diminished barrier compensation capacity seen in older skin.

Human study (n=220)
Wohlrab et al., Skin Pharmacol Physiol (2018)
Ceramide Deficiency & Dry/Atopic Skin (Educational Background)

A review of 12 randomized trials found ceramide-based barrier therapy shows evidence of benefit for dry, atopic skin

Reviewing 12 randomized trials and 11 cohort studies on barrier repair therapy, the authors found some evidence that moisturizer products correcting reduced skin ceramides and natural moisturizing factors improved clinical and biophysical measures in dry, atopic-prone skin, while noting study methods were often limited and further research is warranted.

Systematic review (12 RCTs)
Hon et al., Am J Clin Dermatol (2013)
Ceramide Deficiency & Dry/Atopic Skin (Educational Background)

A review describes how ceramide products were developed to correct skin that is deficient in its own ceramides

Reviewing ceramide and related products, the authors explain that affected skin is deficient in natural moisturizing factors and ceramides, a family of lipids concentrated in the outer skin layer, and describe how this understanding led to the development of ceramide and pseudoceramide products aimed at correcting this deficiency.

Review
Hon & Leung, Recent Pat Inflamm Allergy Drug Discov (2013)
Ceramide Deficiency & Dry/Atopic Skin (Educational Background)

A 2025 review identifies skin ceramide profile as a key biomarker of barrier health

Reviewing recent advances in skin barrier research, the authors describe how alterations in stratum corneum ceramide profiles and structure compromise barrier function, positioning ceramide analysis as a promising biomarker for tracking skin barrier health and guiding future interventions.

Review
Sakai & Hatano, J Dermatol Sci (2025)
Ceramide & Barrier Function - Inflammation and Immune Signaling (Mechanism)

A 2026 review traces how inflammatory signaling disrupts the skin's own ceramide production

Reviewing the immune-metabolic link between inflammation and barrier dysfunction, the authors describe how specific immune signaling pathways alter keratinocyte lipid metabolism, including ceramide synthesis, disrupting the organized lipid structure of the stratum corneum and increasing water loss and permeability.

Review
Andrzejczak et al., Cells (2026)
Ceramide & Barrier Function - Inflammation and Immune Signaling (Mechanism)

A 2026 comparative review names ceramide-based moisturizers as a key strategy for restoring a damaged skin barrier

Comparing barrier dysfunction across contact and atopic dermatitis, the authors identify strategies aimed at barrier restoration, particularly the use of ceramide-based moisturizers, as key therapeutic approaches, while noting that compliance with these interventions remains a practical challenge.

Review
Maeng et al., Allergy Asthma Immunol Res (2026)
Ceramide & Barrier Function - Inflammation and Immune Signaling (Mechanism)

A study found bacteria on affected skin may break down ceramide faster, compounding the deficiency

Comparing skin bacteria from 25 patients with atopic dermatitis and 24 healthy individuals, researchers found bacteria that break ceramide down into other compounds were secreted significantly more from both lesional and non-lesional atopic skin, suggesting microorganisms contribute to the ceramide deficiency seen in this condition.

Case-control study (n=49)
Ohnishi et al., Clin Diagn Lab Immunol (1999)
Wheat Allergen Safety (Substantiating This Product's Own Label Caution)

A 2025 review distinguishes true wheat allergy, which this product's label declares, from celiac disease and gluten sensitivity

Reviewing the three main wheat-related conditions, the authors describe wheat allergy as IgE- and non-IgE-mediated immune reactions distinct from celiac disease (an autoimmune reaction to gluten) and non-celiac wheat sensitivity, each with its own distinct mechanism, diagnosis and management - the same distinction relevant to this product's own labelled wheat allergen.

Review
Stordal & Kurppa, Semin Immunol (2025)
Wheat Allergen Safety (Substantiating This Product's Own Label Caution)

A review clarifies how true food allergy (IgE-mediated) differs from food intolerance

Reviewing the distinction between food allergy and food intolerance, the authors explain that true food allergy is an immunologically mediated hypersensitivity, commonly IgE-driven, that can involve plant proteins including wheat, distinguishing it from non-immunological intolerance reactions.

Review
Kleine-Tebbe et al., Bundesgesundheitsblatt (2016)
Wheat Allergen Safety (Substantiating This Product's Own Label Caution)

A 2026 review identifies the specific wheat protein responsible for the most serious wheat allergy reactions

Reviewing unusual causes of food-induced anaphylaxis, the authors describe wheat-dependent exercise-induced anaphylaxis (WDEIA), in which the major allergen is omega-5 gliadin, a component of wheat's gluten fraction - underscoring why a wheat-derived ingredient like this product's own medicinal ingredient carries a real, labelled allergen caution regardless of any separate gluten-content claim.

Review
Santhosh et al., Indian Dermatol Online J (2026)

Customer Reviews

3.9 out of 5 · 9 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

What is Orange Naturals Skin Bliss with Ceramides and what does it do?

It's a vegetable capsule providing 30 mg of a wheat (Triticum aestivum) seed extract, standardized to 40% digalactosyl diglyceride and 50% ceramides. It helps to reduce skin microwrinkles and increase skin elasticity.

How do I take it?

Adults (19 years and older): take 1 capsule per day.

Does this product contain wheat or gluten?

Yes. This product's only medicinal ingredient is a wheat seed extract, and the real Health Canada label declares wheat as an allergen. If you have a wheat allergy, check with your healthcare practitioner before use. Some marketing describes the ceramide extract itself as gluten-free; this page follows the product's own regulated label, which declares wheat as an allergen and does not itself make a gluten-free claim.

Who should consult a healthcare practitioner before using it?

Ask a healthcare practitioner prior to use if you are pregnant or if you are breastfeeding, or if you have a wheat allergy.

What are the medicinal ingredients?

Each vegetable capsule contains Wheat (seed, Triticum aestivum), 667:1 extract equivalent to 20,000 mg of dry seed, standardized to 40% digalactosyl diglyceride and 50% ceramides, 30 mg.

How long does one bottle last?

Each bottle contains 30 veg capsules - a 30-day supply at the standard dose of 1 capsule per day.

Is it vegan?

Yes. The capsule is vegetable-based and the ingredient panel lists no animal-derived ingredients.

Where do I buy it?

Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.

30 mg Wheat Seed Extract, Standardized to 50% Ceramides, per Capsule30 Veg Capsules - 30-Day Supply at 1 Capsule per DayVegan · 1 Capsule Daily · Contains Wheat (Allergen)Ask a Healthcare Practitioner Before Use if Pregnant or Breastfeeding

Support your skin's own ceramides with Skin Bliss

Get Orange Naturals Skin Bliss with Ceramides on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80118843. Helps to reduce skin microwrinkles and increase skin elasticity. This product's medicinal ingredient is a wheat seed extract; the label declares wheat as an allergen. Ask a healthcare practitioner prior to use if you are pregnant or breastfeeding. The research summaries on this page concern the ingredient generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.

Important information

Safety Information

Cautions and Warnings: Allergens: wheat. Ask a healthcare practitioner prior to use if you are pregnant or if you are breastfeeding. Keep out of reach of children. Do not use if the safety seal is broken.

Indications

Recommended Use or Purpose: Helps to reduce skin microwrinkles and increase skin elasticity.

Ingredients

Medicinal Ingredients (each vegetable capsule contains): Wheat (seed, Triticum aestivum), 667:1 extract equivalent to 20,000 mg of dry seed, standardized to 40% digalactosyl diglyceride and 50% ceramides, 30 mg. Non-medicinal Ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose.

Directions

Recommended Dose (Adults 19 years and older): Take 1 capsule per day.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

$28.99 CAD3.9 ★ (9) Get it on Amazon →