Orange Naturals Peace of Mind Ashwagandha + L-Theanine | 60 V-Caps
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 capsule, 2 times per day |
| Licensed Natural Health Product | NPN 80089995 |
| Quality Standards | Developed by Naturopathic Doctors |
| Country | Made in Canada  |
About this item
- STAY SHARP UNDER PRESSURE: A focused blend of 300 mg KSM-66 Ashwagandha and 100 mg L-Theanine supports mental clarity and composure, helping you stay attentive and focused through demanding workdays.
- EMBRACE RESTFUL EVENINGS: Designed for daily use, these vegetarian capsules gently encourage calm - wind down after busy evenings and support refreshing, restful sleep.
- NAVIGATE DEMANDING MOMENTS: Crafted in Canada, this formula offers reliable support for your body's natural resistance to stress, helping you face daily challenges with greater ease.
- 300 MG KSM-66 ASHWAGANDHA + 100 MG L-THEANINE: Each vegetable capsule delivers KSM-66 ashwagandha root extract (12:1, standardized to 5% withanolides) alongside 100 mg of L-theanine - every amount printed on the label, no proprietary blend.
- THE AUTHORIZED USE: Health Canada licenses this product, NPN 80089995, to help increase resistance to stress.
- VEGAN, NATUROPATH-DEVELOPED FORMULA: Developed by naturopathic doctors and crafted in Canada. Vegan, non-GMO, gluten-free, dairy-free and soy-free, with no artificial colours, flavours or preservatives. 60 vegetable capsules - a 30-day supply at the labelled dose.
Product Description
Peace of Mind - Ashwagandha KSM-66 + L-Theanine
Orange Naturals Peace of Mind pairs 300 mg of KSM-66 ashwagandha root extract (12:1, standardized to 5% withanolides) with 100 mg of L-theanine in one vegan vegetable capsule. Developed by naturopathic doctors and licensed under NPN 80089995 to help increase resistance to stress. Vegan, non-GMO, gluten-free, dairy-free and soy-free - crafted in Canada. Licensed Natural Health Product NPN 80089995.
Sans Souci d'Orange Naturals associe 300 mg d'extrait de racine d'ashwagandha KSM-66 (12:1, normalisé à 5 % de withanolides) à 100 mg de L-théanine, en une seule capsule végétale végane. Développée par des médecins naturopathes et homologuée sous le NPN 80089995 pour aider à augmenter la résistance au stress. Végane, sans OGM, sans gluten, sans produits laitiers et sans soya - fabriquée au Canada.
Two Real Actives. One Daily Calm.
300 mg KSM-66 Ashwagandha + 100 mg L-Theanine - vegan vegetable capsules, developed by naturopathic doctors
300 mg KSM-66 Ashwagandha
A full-spectrum root extract (12:1, equivalent to 3600 mg dry root) standardized to 5% withanolides - the same extract type studied in clinical research on stress and cortisol.
100 mg L-Theanine
The calming amino acid naturally found in tea leaves, paired here at a standalone, label-printed dose - no proprietary blend.
Helps Increase Resistance to Stress
Health Canada licenses this formula, NPN 80089995, for this specific authorized use - not a long list of vague wellness claims.
Developed by Naturopathic Doctors
Orange Naturals formulas, including Peace of Mind, are developed by naturopathic doctors and crafted in Canada.
What Ashwagandha and L-Theanine Support
KSM-66 ashwagandha is among the most clinically studied full-spectrum ashwagandha extracts for stress and cortisol, while L-theanine's role in relaxation and focus has been studied for decades. Here is what the wider research explores.
Calm Resistance to Stress
300 mg of KSM-66 ashwagandha root extract, studied for its effect on stress-related cortisol and perceived-stress scores.
Mental Clarity, Not Drowsiness
100 mg of L-theanine paired alongside ashwagandha, studied for supporting a calm yet focused state.
Restful, Balanced Evenings
A non-habit-forming formula that supports winding down in the evening, so you can wake up feeling renewed.
One Clear Authorized Use
Health Canada licenses this formula, NPN 80089995, to help increase resistance to stress.
Orange Naturals Peace of Mind Ashwagandha + L-Theanine: Supplement Facts
Each Vegetable Capsule Contains:
- KSM-66 Ashwagandha (root, Withania somnifera, 12:1 extract equiv. to 3600 mg dry root, std. to 5% withanolides)300 mg
- L-Theanine100 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose (vegetable capsule), magnesium stearate, microcrystalline cellulose. Vegan, non-GMO, gluten-free, dairy-free, soy-free.
Recommended Use or Purpose: Helps increase resistance to stress.
Recommended Dose (Adults 19 years and older): Take 1 capsule, 2 times per day, or as directed by a health care practitioner.
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner if you have benign prostate hypertrophy and/or prostate cancer. Consult a health care practitioner prior to use if you have been diagnosed with hypoactive sexual disorder, sexual dysfunction or erectile dysfunction, or if you suffer from any psychological disorder and/or condition such as frequent anxiety or depression. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended. Do not use if the safety seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Developed by naturopathic doctors, crafted in Canada by Orange Naturals. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Chaque capsule végétale contient :
- Ashwagandha KSM-66 (racine, Withania somnifera, extrait 12:1 équiv. à 3600 mg de racine sèche, normalisé à 5 % de withanolides)300 mg
- L-théanine100 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose (capsule végétale), stéarate de magnésium, cellulose microcristalline. Végane, sans OGM, sans gluten, sans produits laitiers, sans soya.
Usage ou fins recommandés : Aide à augmenter la résistance au stress.
Dose recommandée (adultes de 19 ans et plus) : Prendre 1 capsule, 2 fois par jour, ou selon l'avis d'un praticien de la santé.
Mises en garde et précautions : Consultez un praticien de la santé avant l'usage si vous êtes enceinte ou allaitez. Consultez un praticien de la santé si vous souffrez d'hypertrophie bénigne de la prostate et/ou de cancer de la prostate. Consultez un praticien de la santé avant l'usage si vous avez reçu un diagnostic de trouble sexuel hypoactif, de dysfonction sexuelle ou de dysfonction érectile, ou si vous souffrez d'un trouble psychologique tel que l'anxiété fréquente ou la dépression. La consommation avec de l'alcool, d'autres médicaments ou produits de santé naturels ayant des propriétés sédatives n'est pas recommandée. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.
NPN 80089995
Meet your daily calm - without the drowsiness
Get Orange Naturals Peace of Mind on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Peace of Mind
300 mg KSM-66 ashwagandha with 100 mg L-theanine - developed by naturopathic doctors, in one vegan vegetable capsule.
300 mg KSM-66 Ashwagandha
A full-spectrum root extract (12:1, standardized to 5% withanolides) - the same extract type studied in stress and cortisol research.
Helps increase resistance to stress
Health Canada-licensed Natural Health Product, NPN 80089995.
100 mg L-Theanine for calm focus
A standalone, label-printed dose of the calming amino acid naturally found in tea leaves - no proprietary blend.
Developed by naturopathic doctors, made in Canada
Orange Naturals formulas are developed by naturopathic doctors and crafted in Canada. Vegan, non-GMO, gluten-free.
Inside every capsule
300 mg of KSM-66 ashwagandha root extract paired with 100 mg of L-theanine, in one vegan vegetable capsule - developed by naturopathic doctors, made in Canada.
How to use it
Take 1 capsule, 2 times per day
Adults (19 years and older): take one (1) vegetable capsule, 2 times per day, or as directed by a health care practitioner.
Swallow with water
Take the vegetable capsule whole with a glass of water.
Consult before combining, if pregnant or breastfeeding
Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you are taking alcohol, other drugs or natural health products with sedative properties.
Check the safety seal
Do not use if the safety seal under the cap is broken. Keep out of reach of children.
What the research says about this formula's ingredients
Educational summaries of published research on KSM-66 ashwagandha and L-theanine, including honest null, mixed and safety-related findings - these are ingredient-level summaries, not claims about this finished product. Orange Naturals Peace of Mind's own claim is the authorized use under NPN 80089995: helping to increase resistance to stress.
A dose-response meta-analysis of 22 RCTs found ashwagandha significantly improved stress, anxiety and depression
Pooling 22 randomized controlled trials, ashwagandha supplementation significantly improved stress (SMD -5.88), depression (SMD -5.68) and anxiety (SMD -6.87) scores compared with placebo, with a significant dose-response relationship between the amount of ashwagandha taken and stress reduction - though the authors note well-designed, high-quality trials are still needed to establish the most effective dosages.
Meta-analysis (22 RCTs)A meta-analysis of 5 RCTs (254 participants) found ashwagandha significantly reduced anxiety and improved several sleep measures
Pooling 5 randomized controlled trials comparing Withania somnifera to placebo, ashwagandha significantly reduced Hamilton Anxiety Scale scores and improved sleep onset latency, total sleep time and sleep efficiency - though not wake-after-sleep-onset or total time in bed - with the authors calling for larger trials to confirm the effect.
Meta-analysis (5 RCTs, n=254)An international clinical taskforce gave ashwagandha a 'modestly supported' rating for anxiety disorders
A joint World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) taskforce of 31 academics and clinicians reviewed Grade-A evidence across nutraceuticals and phytoceuticals for major psychiatric disorders, and rated ashwagandha 'Provisionally Recommended' for anxiety disorders - a similar tier to lavender, while several other popular calming herbs (kava, chamomile) were not recommended for generalized anxiety disorder.
Clinical practice guidelineA meta-analysis in people with diagnosed mental disorders found ashwagandha improved anxiety, depression, stress and sleep quality
Pooling 14 studies (360 people treated with ashwagandha vs 353 controls, median dose 600 mg/day for a median 8 weeks), ashwagandha significantly improved anxiety, depression, stress and sleep-quality symptom scores in people with a diagnosed mental disorder, with no significant difference in safety or tolerability versus comparators - though the authors caution the finding is limited by a small number of studies and substantial heterogeneity.
Meta-analysis (14 studies)An early systematic review found all 5 identified human trials favored ashwagandha over placebo for anxiety
Screening 62 abstracts down to 5 qualifying human randomized trials, this review found every study favored ashwagandha over placebo or comparator on anxiety or stress scales - including a 44% reduction in Perceived Stress Scale scores versus a 5.5% reduction with placebo in one trial - though the authors caution that all 5 studies carried unclear-to-high risk of bias and heterogeneous methods prevented a formal meta-analysis.
Systematic review (5 human trials)A network meta-analysis found ashwagandha significantly reduced anxiety scores, while L-theanine alone did not outperform placebo
Comparing 12 medicinal herbs across 29 randomized trials for diagnosed or subthreshold anxiety, this Bayesian network meta-analysis found Withania somnifera (ashwagandha) significantly reduced Hamilton Anxiety Scale scores versus placebo, though the trials were limited by small sample sizes - while L-theanine, evaluated separately as its own herbal treatment arm in this network, did not significantly outperform placebo. All herbs, including both, showed good tolerability and safety.
Network meta-analysis (29 trials, 12 herbs)A randomized trial in stressed adults found an ashwagandha root extract sustained-release capsule improved cognitive function, stress and sleep quality
In 130 healthy but stressed adults (Perceived Stress Scale 14-24) given either an ashwagandha root extract sustained-release capsule (300 mg) or placebo daily for 90 days, the ashwagandha group showed significantly greater improvement in cognitive function testing alongside reductions in perceived stress and improvements in sleep quality and overall well-being.
Human RCT (n=130)A trial in healthy young adults found both acute and repeated ashwagandha supplementation improved cognitive-function testing and mood
In 59 healthy young men and women given a single 225 mg dose of a liposomal ashwagandha root extract or placebo and tested on a computerized cognitive-function battery (word recall, reaction time, Stroop test) and mood profile, ashwagandha supplementation was associated with improved markers of cognitive function and mood versus placebo, in a younger, non-clinical population where such effects had previously been unclear.
Human RCT (n=59)A trial found 600 mg/day of ashwagandha root extract improved cognition, mood and mental fatigue in adults with self-reported problems
In adults aged 30-75 with self-reported cognitive and energy problems, 8 weeks of 600 mg/day ashwagandha root extract produced significantly greater improvement than placebo on a computerized cognitive-performance battery, along with better mood-state and mental-fatigue scores.
Human RCTA 12-week trial in adults aged 65-80 found ashwagandha root extract improved general well-being and sleep
In a randomized, double-blind, placebo-controlled study of adults aged 65 to 80, 12 weeks of ashwagandha root extract improved measures of general health, quality of life and sleep versus placebo, with the treatment well tolerated in this older population.
Human RCT (elderly)A double-blind trial found ashwagandha root extract improved both insomnia severity and anxiety scores
In this randomized, placebo-controlled study, ashwagandha root extract significantly improved sleep quality and reduced anxiety scores compared with placebo in participants with insomnia, consistent with the ingredient's traditional use as a sleep aid in Ayurvedic medicine.
Human RCTA meta-analysis of 5 trials (400 participants) found a small but significant overall sleep benefit from ashwagandha
Pooling 5 randomized controlled trials, ashwagandha extract showed a small but statistically significant effect on overall sleep (Standardized Mean Difference -0.59) versus placebo, with secondary improvements also noted in mental alertness on rising, anxiety and quality of life.
Meta-analysis (5 RCTs, n=400)L-theanine reduced heart-rate and immune-marker responses to an acute mental stress task
In a double-blind, counterbalanced trial, 12 participants given L-theanine before or during a mental-arithmetic stressor showed a reduced heart-rate and salivary immunoglobulin A response to the acute stress task compared with placebo, with heart-rate-variability analysis suggesting the effect was linked to reduced sympathetic nervous system activation.
Human RCT (n=12)An L-theanine drink reduced subjective stress and cortisol response to a cognitive stressor, with no measured change in cognitive performance itself
In 34 healthy adults, an L-theanine-based nutrient drink significantly reduced subjective stress response and salivary cortisol response to a multitasking cognitive stressor compared with placebo, and increased resting-state alpha brain activity on magnetoencephalography in those higher in trait anxiety - though no treatment-related change in cognitive performance itself was observed, an honest null alongside the positive stress-marker findings.
Human RCT (n=34)A meta-analysis found theanine, alone or with caffeine, may modestly benefit cognition and mood, with considerable uncertainty
Reviewing 50 randomized controlled trials of tea, theanine or theanine-plus-caffeine (15 eligible for meta-analysis), theanine alone showed a small improvement in choice reaction time versus placebo, and theanine plus caffeine showed small-to-moderate benefits on measures like digit vigilance accuracy and overall mood in the first two hours after intake - though the authors note confidence intervals frequently left the true size and direction of these effects uncertain.
Meta-analysis (50 RCTs reviewed, 15 pooled)A tea-strength dose of theanine countered caffeine's blood-pressure rise but did not significantly change mood or alertness
In 48 healthy adults given caffeine, theanine, both or neither at doses relevant to regular tea drinking, theanine blunted caffeine's blood-pressure-raising effect but did not significantly affect self-rated jitteriness, alertness or other mood measures, and slowed reaction time slightly on a visual-probe task - an honestly mixed result rather than a uniform calming or performance benefit.
Human RCT (n=48)An honest null finding: L-theanine showed no significant anti-anxiety effect under an experimentally induced anxiety state
Comparing L-theanine (200 mg), the benzodiazepine alprazolam (1 mg) and placebo in 16 healthy volunteers, L-theanine showed some relaxing effect on a mood subscale under resting baseline conditions, but neither L-theanine nor alprazolam produced a significant anti-anxiety effect once anxiety was experimentally induced - a reminder that a relaxing effect at rest does not always translate to an anti-anxiety effect under acute anxious conditions.
Human RCT (n=16)In elite curling athletes, combined caffeine and L-theanine improved shooting accuracy and reaction time more than either alone
In 22 elite national curling athletes given caffeine, L-theanine, the combination, or placebo across four sessions, the combined caffeine-plus-L-theanine intake produced the best shooting scores and the fastest, most accurate cognitive (Stroop-test) performance - outperforming either ingredient taken alone.
Human RCT (n=22, crossover)A systematic review identified ashwagandha as one of 10 plant medicines with real evidence of acting on the brain's GABA system for anxiety
Reviewing preclinical and clinical evidence from in-vitro GABA-receptor studies through animal anxiety models to human trials, this systematic review identified ten phytomedicines - including ashwagandha, alongside kava, valerian, chamomile and Ginkgo biloba - with evidence of GABA-pathway modulation and human clinical trial data, with anxiolytic effects comparable to some pharmaceuticals and generally good safety and tolerability.
Systematic review (preclinical + clinical)A 2025 review says L-theanine's mechanism is plausible, but rigorous human trials 'do not yet match the hype'
Surveying L-theanine's chemistry, metabolism and purported effects, this review confirms it is well absorbed and crosses the blood-brain barrier, with some studies linking it to increased relaxation-associated alpha brain waves and improved sleep quality - but the authors caution that findings are often inconsistent, rigorous human trials remain limited, and 'the science does not yet match the hype' behind this popular supplement.
ReviewA meta-analysis of 12 RCTs (1,002 participants) found ashwagandha significantly reduced both anxiety and stress
Pooling 12 randomized controlled trials in adults aged 25-48, ashwagandha supplementation significantly reduced anxiety (SMD -1.55) compared with placebo, addressing what the authors describe as previously conflicting trial-level results on the herb's anxiety and stress effects.
Meta-analysis (12 RCTs, n=1,002)A safety sub-study found subtle thyroid-hormone increases with ashwagandha, suggesting vigilance for hyperthyroidism
Measuring thyroid indices (TSH, free T4, T3) during an 8-week ashwagandha trial in patients with bipolar disorder, all 3 ashwagandha-treated patients showed thyroxine (T4) increases from baseline (7-24%), prompted by a prior case report of ashwagandha-associated thyrotoxicosis and animal data showing similar increases - the small sub-study's authors concluded the subtle changes suggest vigilance regarding hyperthyroidism may be warranted.
Human RCT sub-study safety data (n=10 with thyroid data)A published case report describes ashwagandha-associated acute-on-chronic liver failure in a patient with pre-existing liver disease
This case report describes a patient with pre-existing liver conditions who developed life-threatening acute-on-chronic liver failure associated with ashwagandha use, with the authors concluding that ashwagandha carries real hepatotoxicity risk particularly for people with pre-existing liver disease, and calling for public education on herbal-supplement risks.
Case reportA case report links ashwagandha, alongside high-dose acetaminophen, to acute toxic hepatitis in a multiple sclerosis patient
A 39-year-old patient on immunomodulatory MS therapy developed jaundice and abnormal liver enzymes after a week of recent high-dose acetaminophen use combined with an ashwagandha-containing dietary supplement; autoimmune and infectious causes were ruled out, and liver function normalized after stopping both the supplement and acetaminophen and starting corticosteroid therapy. The authors note the case highlights the difficulty of isolating a single herbal supplement's contribution when taken alongside other known hepatotoxic substances.
Case reportFrequently asked questions
What is Orange Naturals Peace of Mind and what does it do?
It's a Health Canada-licensed Natural Health Product combining 300 mg of KSM-66 ashwagandha root extract with 100 mg of L-theanine in one vegan vegetable capsule. Its authorized use is to help increase resistance to stress. NPN 80089995.
How do I take it?
Adults (19 years and older) take 1 capsule, 2 times per day, or as directed by a health care practitioner. One 60-capsule bottle is a 30-day supply at this dose.
What is KSM-66?
KSM-66 is a full-spectrum ashwagandha (Withania somnifera) root extract, standardized to 5% withanolides, among the most clinically studied ashwagandha extracts.
Will it make me feel drowsy?
This formula pairs ashwagandha with L-theanine, an amino acid studied for supporting calm focus rather than sedation. As with any supplement, individual responses vary.
Who should not use it, or should consult a practitioner first?
Consult a health care practitioner prior to use if you are pregnant or breastfeeding; if you have benign prostate hypertrophy and/or prostate cancer; if you have been diagnosed with hypoactive sexual disorder, sexual dysfunction or erectile dysfunction; or if you suffer from any psychological disorder such as frequent anxiety or depression. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended.
How is this different from Orange Naturals L-Theanine with Magnesium?
L-Theanine with Magnesium pairs 250 mg of L-theanine with 20 mg of magnesium bisglycinate - an amino-acid-plus-mineral pairing, with no ashwagandha at all. Peace of Mind instead pairs a much higher single-herb dose, 300 mg of KSM-66 ashwagandha root extract, with a smaller 100 mg dose of L-theanine - a different active ingredient and a different formula entirely.
How is this different from Orange Naturals Bounce Back Adrenal Recharge?
Bounce Back is an 8-ingredient adaptogen blend where ashwagandha is just one of several actives at a lower, differently standardized dose, with no L-theanine at all. Peace of Mind is a focused 2-ingredient formula built around a much higher, standardized 300 mg KSM-66 ashwagandha dose paired specifically with L-theanine.
Is it vegan and made in Canada?
Yes - the label states this product is vegan, non-GMO, gluten-free, dairy-free and soy-free, developed by naturopathic doctors and crafted in Canada.
Meet your daily calm - without the drowsiness
Get Orange Naturals Peace of Mind on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80089995. Helps increase resistance to stress. The research summaries below concern KSM-66 ashwagandha and L-theanine generally and are educational - they are not claims about this finished product. Read and follow the label. Keep out of reach of children. Do not use if the safety seal is broken. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, have benign prostate hypertrophy and/or prostate cancer, have been diagnosed with hypoactive sexual disorder, sexual dysfunction or erectile dysfunction, or suffer from any psychological disorder such as frequent anxiety or depression. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner if you have benign prostate hypertrophy and/or prostate cancer. Consult a health care practitioner prior to use if you have been diagnosed with hypoactive sexual disorder, sexual dysfunction or erectile dysfunction, or if you suffer from any psychological disorder and/or condition such as frequent anxiety or depression. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended. Do not use if the safety seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps increase resistance to stress.
Ingredients
Medicinal Ingredients (1 Vegetable Capsule): KSM-66 Ashwagandha (root, Withania somnifera) 12:1 extract equivalent to 3600 mg dry root, standardized to 5% withanolides, 300 mg; L-Theanine 100 mg. Non-medicinal ingredients: Hypromellose (vegetable capsule), magnesium stearate, microcrystalline cellulose. Vegan, non-GMO, gluten-free, dairy-free, soy-free.
Directions
Recommended Dose (Adults 19 years and older): Take 1 capsule, 2 times per day, or as directed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Developed by naturopathic doctors, crafted in Canada by Orange Naturals. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.