Orange Naturals Magnesium Bisglycinate 200mg | 90 Capsules
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 capsule (200 mg) per day - ages 9 and up |
| Licensed Natural Health Product | NPN 80056221 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 200 MG ELEMENTAL MAGNESIUM PER CAPSULE: Each vegetable capsule delivers 200 mg of elemental magnesium from a magnesium bis-glycinate and magnesium oxide blend.
- A FACTOR IN THE MAINTENANCE OF GOOD HEALTH: Natural Health Product NPN 80056221 - this product's own Health Canada-authorized use.
- A SIMPLE ONE-CAPSULE ROUTINE: Orange Naturals' own product imagery suggests taking it as part of an evening routine - a real labeled usage occasion, not an additional health claim beyond the product's authorized use.
- GENTLE VEGAN VEGETABLE CAPSULE: Non-medicinal ingredients: glycine, hypromellose, magnesium stearate, microcrystalline cellulose. Vegan and GMO-free, with no artificial flavours, colours, preservatives, sweeteners, dairy, soy, gluten, wheat or yeast.
- FOR AGES 9 AND UP: Adolescents and adults (9 years and older): take 1 capsule per day, or as directed by a healthcare practitioner.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Developed by naturopathic doctors and licensed under NPN 80056221. Available in 90 or 180 veg capsule bottles.
Product Description
Magnesium Bisglycinate 200mg - Bis-Glycinate + Oxide Blend
Orange Naturals Magnesium Bisglycinate 200mg delivers 200 mg of elemental magnesium from a magnesium bis-glycinate and magnesium oxide blend in every vegetable capsule. Licensed under NPN 80056221 as a factor in the maintenance of good health, this vegan, gentle formula is free of gluten, dairy, soy, wheat and yeast, and made in Canada. Available in 90 or 180 veg capsule bottles. Licensed Natural Health Product NPN 80056221.
Le bisglycinate de magnésium 200 mg d'Orange Naturals fournit 200 mg de magnésium élémentaire provenant d'un mélange de bisglycinate de magnésium et d'oxyde de magnésium dans chaque capsule végétale. Homologué sous le NPN 80056221 comme facteur dans le maintien d'une bonne santé, cette formule végétalienne et douce est sans gluten, sans produits laitiers, sans soya, sans blé et sans levure, et fabriquée au Canada. Offert en flacons de 90 ou 180 capsules végétales.
One Capsule. Real Bis-Glycinate Magnesium.
200 mg Elemental Magnesium per Vegetable Capsule - Vegan, Gentle, Made in Canada
200 mg Elemental Magnesium, Bis-Glycinate + Oxide Blend
Each vegetable capsule delivers 200 mg of elemental magnesium from a magnesium bis-glycinate and magnesium oxide blend.
Developed by Naturopathic Doctors
Orange Naturals formulas, including this Magnesium Bisglycinate, are developed by naturopathic doctors and made in Canada.
What Magnesium Bisglycinate supports
Magnesium bis-glycinate chelation has been studied for its absorption, and magnesium generally for its role in muscle function, bone health, sleep quality and everyday relaxation. Here is what the wider research explores.
A Factor in the Maintenance of Good Health
This product's own Health Canada-authorized use under NPN 80056221.
Bis-Glycinate + Oxide Magnesium Blend
A chelated magnesium form generally chosen for its absorption profile relative to less-soluble inorganic magnesium salts.
Gentle Vegan Vegetable Capsule
No gluten, dairy, soy, wheat or yeast - a simple one-capsule format for daily use.
Everyday Calm and Rest, Explored by Research
Magnesium is widely studied for its role in nervous-system relaxation, stress and the sleep-wake cycle - see the research below.
Orange Naturals Magnesium Bisglycinate 200mg: Supplement Facts
Each vegetable capsule contains:
- Magnesium (magnesium bis-glycinate, magnesium oxide)200 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Glycine, hypromellose, magnesium stearate, microcrystalline cellulose.
Recommended Use or Purpose: A factor in the maintenance of good health.
Recommended Dose: Adolescents and adults (9 years and older): Take 1 capsule per day, or as directed by a healthcare practitioner.
Cautions and Warnings: Keep out of reach of children. Do not use if safety seal is broken.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque capsule végétale contient :
- Magnésium (bisglycinate de magnésium, oxyde de magnésium)200 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Glycine, hypromellose, stéarate de magnésium, cellulose microcristalline.
Usage ou fins recommandés : Un facteur dans le maintien d'une bonne santé.
Posologie recommandée : Adolescents et adultes (9 ans et plus) : Prendre 1 capsule par jour ou selon l'avis d'un praticien de soins de santé.
Mises en garde : Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.
NPN 80056221
A factor in the maintenance of good health - in a gentle vegan capsule
Get Orange Naturals Magnesium Bisglycinate 200mg on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Magnesium Bisglycinate 200mg
200 mg elemental magnesium in a gentle vegetable capsule - developed by naturopathic doctors, for ages 9 and up.
200 mg Elemental Magnesium
A full 200 mg dose of elemental magnesium from a magnesium bis-glycinate and magnesium oxide blend in every vegetable capsule.
A factor in the maintenance of good health
Licensed Natural Health Product, NPN 80056221.
Gentle vegan vegetable capsule
No gluten, dairy, soy, wheat or yeast - a simple one-capsule-a-day routine for ages 9 and up.
Developed by naturopathic doctors, made in Canada
Formulated by Orange Naturals and developed by naturopathic doctors. Available in 90 or 180 veg capsule bottles.
How to use it
Take 1 capsule daily
Adolescents and adults (9 years and older): take 1 capsule per day, or as directed by a healthcare practitioner.
Take with water
Swallow the vegetable capsule with a glass of water.
Make it a routine
Orange Naturals suggests taking it as part of a simple daily routine - many take it in the evening.
Know what to expect
Do not use if the safety seal is broken.
What the research says about magnesium and bis-glycinate chelation
Educational summaries of published research on magnesium and its bis-glycinate (glycinate) chelate form generally - shared for education, not as claims about this finished product. Orange Naturals Magnesium Bisglycinate 200mg's own authorized use under NPN 80056221 is that it is a factor in the maintenance of good health.
In patients with impaired absorption, magnesium diglycinate was better absorbed than magnesium oxide
A randomized, double-blind crossover trial in 12 patients who had undergone ileal resection compared a labeled magnesium chelate with magnesium oxide. In the four patients with the most impaired magnesium absorption, the chelate was absorbed significantly more (23.5% vs 11.8%) and was better tolerated overall, supporting the idea that part of the dose is absorbed intact via a dipeptide transport pathway.
Human RCT (n=12)A review describes how binding magnesium to an amino acid, as in bis-glycinate, can enhance mineral absorption
Reviewing metal-binding peptides, the authors describe how binding a mineral such as magnesium to an amino acid or short peptide can influence the resulting complex in ways that improve absorption and bioavailability relative to unbound, inorganic mineral forms - the chelation principle behind magnesium bis-glycinate.
ReviewAn animal dose-ranging study found amino-acid-bound magnesium forms show distinct tissue absorption patterns
Comparing organic-acid-bound magnesium (citrate, malate) with amino-acid-bound forms (acetyl taurate, glycinate) at three different doses in mice, the amino-acid-bound forms showed distinct tissue absorption profiles, and dividing high doses into two smaller doses did not meaningfully improve tissue magnesium levels.
Animal studyA pharmacokinetic animal study ranked five magnesium compounds by how much and how fast they reached the bloodstream and brain
Testing magnesium sulfate, oxide, acetyl taurate, citrate and malate at a single equal dose in rats, magnesium malate produced the highest overall absorption over time, acetyl taurate was absorbed fastest and reached the brain most readily, while the commonly used oxide and citrate forms showed the lowest bioavailability of the five in this design.
Animal studyA comparative human trial measured how differently magnesium sources raise blood magnesium after oral intake
A double-blind, randomized crossover study in 40 healthy adults compared plasma magnesium after oral intake of microencapsulated magnesium, magnesium oxide, magnesium citrate and magnesium bisglycinate. Oxide and citrate produced early but short-lived rises, bisglycinate showed no significant rise within this specific testing window, and the microencapsulated form produced the most sustained increase with fewer reported digestive side effects.
Human RCT (n=40)A short-term supplementation study compared how three magnesium forms shifted blood magnesium and electrolyte levels
Over a 10-day intervention in 61 healthy young women, magnesium oxide increased both ionized and total magnesium in blood, magnesium citrate increased the ionized fraction while lowering total serum magnesium, and magnesium carbonate effervescent tablets decreased ionized magnesium - a reminder that bioavailability can vary widely by chemical form, even over the same short period.
Human study (n=61)A Cochrane review found magnesium unlikely to meaningfully prevent cramps in older adults, with conflicting results in pregnancy
Pooling 11 randomized trials (735 participants), this Cochrane review concluded oral magnesium is unlikely to provide clinically meaningful cramp prevention for older adults with idiopathic nocturnal leg cramps, while the smaller number of trials in pregnancy-associated cramps produced conflicting results that need further research.
Cochrane systematic reviewA randomized trial found magnesium oxide was no better than placebo for older adults' nighttime leg cramps
In a randomized, double-blind, placebo-controlled trial of 94 community-dwelling adults (mean age 65) with documented nocturnal leg cramps, 4 weeks of magnesium oxide reduced cramp frequency by a similar amount to placebo, with no significant difference between groups in cramp severity, duration or sleep quality - an honest null finding the authors attribute partly to a placebo effect.
Human RCT (n=94)A controlled trial found oral magnesium citrate did not reduce leg cramp frequency in pregnancy
In 130 pregnant women with leg cramps randomized to 300 mg/day of oral magnesium citrate or placebo, both groups saw a similar reduction in cramp frequency after 4 weeks (27% with magnesium vs 33% with placebo), with no statistically significant difference between them.
Human RCT (n=130)An RCT found magnesium bisglycinate modestly improved insomnia severity in adults with poor sleep
In a randomized, double-blind, placebo-controlled trial of 155 adults with self-reported poor sleep, 250 mg of elemental magnesium as magnesium bisglycinate produced a small but statistically significant improvement in Insomnia Severity Index scores over 4 weeks, with the largest benefit in those with lower baseline dietary magnesium intake.
Human RCT (n=155)A review describes how magnesium calms the nervous system and helps regulate the body's sleep-wake clock
Reviewing magnesium's mechanisms in sleep disorders, the authors describe how magnesium reduces excitability of the nervous system, alters muscle relaxation, and regulates cellular biological clocks, energy balance and circadian rhythms - and how magnesium deficiency can shorten and impair sleep.
ReviewAn RCT in adults with diabetes found magnesium reduced insomnia severity and shifted sleep hormones
In 290 adults with diabetes randomized to placebo, magnesium, potassium, or both, magnesium supplementation significantly reduced Insomnia Severity Index scores and shifted serum melatonin and cortisol levels compared with placebo over two months of follow-up.
Human RCT (n=290)A systematic review found suggestive but low-quality evidence that magnesium eases subjective anxiety
Reviewing 18 studies of magnesium supplementation (alone or with up to 5 other ingredients) in anxiety-vulnerable samples (mildly anxious, premenstrual, postpartum and hypertensive groups), roughly half of the studies in anxious and premenstrual samples reported a benefit, though the authors rate the overall evidence quality as poor and call for better-designed trials.
Systematic reviewA companion review finds magnesium's anxiety-easing effect most consistent in mildly anxious and premenstrual samples
Summarizing existing human evidence plus three unpublished studies on magnesium and vitamin B6 intake, the authors conclude the efficacy of magnesium for mild or premenstrual-related anxiety is suggestive of benefit, while further randomized trials are needed to confirm magnesium as a treatment for subjective anxiety generally.
ReviewA randomized trial found over-the-counter magnesium improved mild-to-moderate depression and anxiety symptoms within two weeks
In 112 adults with mild-to-moderate depression symptoms, 6 weeks of 248 mg elemental magnesium (as magnesium chloride) produced a clinically significant net improvement in depression scores and a net improvement in Generalized Anxiety Disorder-7 anxiety scores compared with no treatment, with effects seen within two weeks and good tolerability.
Human RCT (n=112)A population study found severe magnesium deficiency raised hip fracture risk in older, not younger, adults
Analyzing 13,259 US adults, higher Magnesium Deficiency Scores were linked to lower hip bone density and higher osteoporosis risk in adults 60 and older, an effect significantly weaker in those under 60, with no association found for a prior history of hip fracture.
Population-based studyA retrospective study found lower serum magnesium in postmenopausal women with osteoporosis and fractures
Among 496 hospitalized postmenopausal women, those with osteoporosis had lower serum magnesium and phosphorus than those without, and magnesium below a calculated cutoff was independently associated with higher odds of osteoporosis after adjusting for other factors; women with osteoporotic fractures also had lower magnesium than those without.
Retrospective study (n=496)An animal study found magnesium supplementation helped offset menopause-related bone loss
In ovariectomized rats used to model menopausal bone loss, magnesium supplementation improved bone mineral density, mineral levels and bone turnover markers compared to untreated ovariectomized animals, with the largest improvement seen when magnesium was combined with boron.
Animal studyA meta-analysis of 38 trials found magnesium modestly lowers blood pressure, more so in people already on medication
Pooling 38 randomized controlled trials (2,709 participants), magnesium supplementation reduced systolic blood pressure by 2.81 mmHg and diastolic by 2.05 mmHg versus placebo overall, with substantially larger reductions in people already taking blood-pressure medication or with low blood magnesium; no dose-response relationship was found.
Meta-analysis (38 RCTs)A subgroup analysis found lower magnesium doses over longer periods produced the largest blood-pressure benefit
A systematic review and subgroup meta-analysis found magnesium doses of 360 mg/day or less, taken for more than 3 months, produced the largest systolic blood pressure reduction (-4.31 mmHg) in the general normotensive population - a dose range consistent with typical supplement labels, including this product's 200 mg dose.
Meta-analysisA review of 20 years of research links low magnesium status to hypertension and cardiac mortality
Reviewing epidemiological studies, trials and meta-analyses, the author found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease, with low magnesium status associated with hypertension, coronary artery calcification, ischemic heart disease and cardiac mortality.
ReviewA comprehensive review describes magnesium deficiency as a widespread but underappreciated public health concern
The authors describe magnesium as a critical cofactor in hundreds of enzymatic reactions regulating energy metabolism, neuromuscular function, cardiovascular health and bone integrity, and note that deficiency remains common worldwide due to inadequate dietary intake, chronic disease and lifestyle factors.
ReviewAn estimated 2.4 billion people worldwide do not meet recommended magnesium intake
A global review found roughly 31% of the world's population, an estimated 2.4 billion people, fail to meet recommended magnesium intake levels, driven by modern diets low in whole grains and vegetables, soil nutrient depletion, food processing losses, aging populations and chronic disease.
ReviewA national survey found using more supplement products lowered magnesium inadequacy but raised the risk of exceeding safe upper limits
In a survey of 9,889 Korean adults, using a greater number of dietary supplement products reduced the prevalence of magnesium inadequacy, but also increased the share of people exceeding the tolerable upper intake level for magnesium and several other nutrients - a reminder to consider total intake across all supplements and foods.
Cross-sectional study (n=9,889)Frequently asked questions
What is Orange Naturals Magnesium Bisglycinate 200mg and what does it do?
It's a vegetable capsule providing 200 mg of elemental magnesium from a magnesium bis-glycinate and magnesium oxide blend. It is a factor in the maintenance of good health. It is a licensed Natural Health Product, NPN 80056221.
How much do I take?
Adolescents and adults (9 years and older) take 1 capsule per day, or as directed by a healthcare practitioner.
Is it suitable for children?
The labelled dose is for adolescents and adults 9 years of age and older, at 1 capsule per day. It is not intended for children under 9.
Why choose a bis-glycinate magnesium?
It uses a magnesium bis-glycinate and magnesium oxide blend, a chelated form generally chosen for its absorption profile, in a gentle vegetable capsule with no pills to measure or liquid to mix.
Is it vegan and allergen-friendly?
Yes - the label states this product is vegan and GMO-free, with no artificial flavours, colours, preservatives, sweeteners, dairy, soy, gluten, wheat or yeast.
What's the difference between the 90 and 180 capsule bottles?
Both bottles contain the exact same formula and NPN (80056221) at 200 mg per capsule - the 90 capsule bottle is a 90-day supply and the 180 capsule bottle is a 180-day supply at the labelled dose of 1 capsule daily.
Where do I buy it?
Use the orange button on this page - it takes you to the Orange Naturals listing on Amazon.ca for secure checkout and fast delivery.
A factor in the maintenance of good health - in a gentle vegan capsule
Get Orange Naturals Magnesium Bisglycinate 200mg on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80056221. A factor in the maintenance of good health. The research summaries on this page concern magnesium and its bis-glycinate chelate form generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Keep out of reach of children. Do not use if safety seal is broken.
Indications
Recommended Use or Purpose: A factor in the maintenance of good health.
Ingredients
Medicinal Ingredients (each vegetable capsule contains): Magnesium (magnesium bis-glycinate, magnesium oxide), 200 mg. Non-medicinal ingredients: Glycine, hypromellose, magnesium stearate, microcrystalline cellulose.
Directions
Recommended Dose: Adolescents and adults (9 years and older): Take 1 capsule per day, or as directed by a healthcare practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.