Orange Naturals Heart Health Tincture | 100mL
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 2 mL, 3 times per day |
| Licensed Natural Health Product | NPN 80036773 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- MAINTAINS AND SUPPORT CARDIOVASCULAR HEALTH: Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
- MADE FROM ORGANIC AND WILD CRAFTED HERBS: Made from organic and wild crafted hawthorn, garlic, linden and motherwort.
- THERAPEUTIC DOSE OF CONDITION-SPECIFIC HERBS: 156.25 mg Hawthorn, 31.25 mg Garlic, 25 mg Linden and 25 mg Motherwort per mL - a 4-herb blend traditionally associated with cardiovascular support.
- RAPIDLY ABSORBED TINCTURE FORMAT: Tinctures are rapidly absorbed and metabolized - absorption begins in the mouth, allowing the body to absorb up to 98% of the medicinal components.
- LARGE 100 ML BOTTLE SIZE: Large 100 mL bottle size offers great value - take 2 mL, 3 times per day on an empty stomach.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80036773.
Product Description
Heart Health Tincture - Traditional 4-Herb Cardiovascular Support
Orange Naturals Heart Health Tincture combines four traditional cardiovascular herbs - Hawthorn (156.25 mg), Garlic (31.25 mg), Linden (25 mg) and Motherwort (25 mg) per mL - in a fast-absorbing naturopathic tincture. Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults. This 100 mL tincture is licensed as a Natural Health Product. Licensed Natural Health Product NPN 80036773.
Teinture Santé du Cœur d'Orange Naturals combine quatre plantes traditionnelles pour la santé cardiovasculaire - Aubépine (156,25 mg), Ail (31,25 mg), Tilleul (25 mg) et Agripaume (25 mg) par mL - dans une teinture naturopathique à absorption rapide. Utilisée traditionnellement en phytothérapie pour aider à maintenir et soutenir la santé cardiovasculaire chez les adultes. Cette teinture naturopathique de 100 mL est homologuée comme produit de santé naturel. NPN 80036773.
Four Traditional Herbs, One Fast-Absorbing Tincture
Hawthorn, Garlic, Linden and Motherwort - fast-absorbing liquid format, 2 mL 3 times daily on an empty stomach
4-Herb Cardiovascular Blend
Each mL delivers 156.25 mg Hawthorn, 31.25 mg Garlic, 25 mg Linden and 25 mg Motherwort - traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
Fast-Absorbing Tincture Format
As a liquid tincture, this blend can begin absorbing in the mouth, offering a fast-acting alternative to capsules or tablets - take 2 mL, 3 times per day on an empty stomach.
Advanced Ingredients, Superior Results
Hawthorn, Garlic, Linden and Motherwort are traditional herbs long associated with cardiovascular and heart-health support. Here is what the wider research explores about each.
Hawthorn (fruit, Crataegus laevigata)
One of the most widely studied traditional cardiovascular herbs, explored for its role in heart failure symptom management, blood pressure and circulation.
156.25 mg per mL, 1:4 extractGarlic (bulb, Allium sativum)
A traditional bulb studied for its role in blood pressure support and healthy blood lipid levels.
31.25 mg per mL, 1:4 extract, organically grown
Linden (flower, Tilia cordata)
A traditional calming flower, long used to help relieve restlessness and nervousness.
25 mg per mL, 1:5 extractMotherwort (herb, Leonurus cardiaca)
A traditional herb historically combined with hawthorn in European herbal medicine for heart-focused formulas.
25 mg per mL, 1:5 extract, organically grownOrange Naturals Heart Health Tincture: Supplement Facts
Each mL contains:
- Hawthorn (fruit, Crataegus laevigata), 1:4 extract156.25 mg
- Garlic (bulb, Allium sativum), 1:4 extract, organically grown31.25 mg
- Linden (flower, Tilia cordata), 1:5 extract25 mg
- Motherwort (herb, Leonurus cardiaca), 1:5 extract, organically grown25 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: 40% grain alcohol, purified water.
Recommended Use or Purpose: Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
Recommended Dose (Adults): Take 2 mL, 3 times per day on an empty stomach. Use for a minimum of 2 months to see beneficial effects.
Cautions and Warnings: Consult a healthcare practitioner if symptoms persist or worsen. Consult a healthcare practitioner prior to use if you are taking any medication including blood thinners, protease inhibitors or cardiac glycosides such as digitalis/digoxin, or blood pressure medication, or if you have a medical condition including diabetes. Do not use if seal is broken. Keep out of reach of children. Contra-Indications: Do not use if you are pregnant or breastfeeding. Known Adverse Reactions: Hypersensitivity (e.g. allergy) has been known to occur; in which case, discontinue use.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque mL contient :
- Aubépine (fruit, Crataegus laevigata), extrait 1:4156.25 mg
- Ail (bulbe, Allium sativum), extrait 1:4, biologique31.25 mg
- Tilleul (fleur, Tilia cordata), extrait 1:525 mg
- Agripaume (plante, Leonurus cardiaca), extrait 1:5, biologique25 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Alcool de grain à 40 %, eau purifiée.
Usage ou fins recommandés : Utilisé traditionnellement en phytothérapie pour aider à maintenir et soutenir la santé cardiovasculaire chez les adultes.
Posologie recommandée (adultes) : Prendre 2 mL, 3 fois par jour sur un estomac vide. Utiliser pendant un minimum de 2 mois pour observer les bienfaits.
Mises en garde : Consulter un praticien de la santé si les symptômes persistent ou s'aggravent. Consulter un praticien de la santé avant l'usage si vous prenez tout médicament, y compris des anticoagulants, des inhibiteurs de protease ou des glycosides cardiaques tels que la digitale/digoxine, ou des médicaments pour la tension artérielle, ou si vous avez un problème de santé y compris le diabète. Ne pas utiliser si le sceau est brisé. Garder hors de la portée des enfants. Contre-indications : Ne pas utiliser si vous êtes enceinte ou allaitez. Effets indésirables connus : De l'hypersensibilité (p. ex. allergie) a été observée; le cas échéant, cesser l'utilisation.
NPN 80036773
Support your heart with a 4-herb traditional blend
Get Orange Naturals Heart Health Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Heart Health Tincture
156.25 mg Hawthorn, 31.25 mg Garlic, 25 mg Linden and 25 mg Motherwort per mL - four traditional herbs in a fast-absorbing tincture format.
156.25 mg Hawthorn per mL
Each mL delivers a full 156.25 mg dose of organic Hawthorn (Crataegus laevigata) fruit, extracted at a 1:4 ratio - the formula's dominant herb.
Traditionally used for cardiovascular health
Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
Fast-absorbing liquid tincture
Take 2 mL, 3 times per day on an empty stomach - a fast-acting alternative to capsules.
Made in Canada, Health Canada licensed
Formulated by Orange Naturals and licensed as a Natural Health Product. NPN 80036773.
Inside every mL
156.25 mg Hawthorn (Crataegus laevigata), 31.25 mg Garlic (Allium sativum), 25 mg Linden (Tilia cordata) and 25 mg Motherwort (Leonurus cardiaca) - take 2 mL, 3 times per day on an empty stomach. Non-medicinal ingredients: 40% grain alcohol and purified water.
How to use it
Take 2 mL, 3 times daily on an empty stomach
Adults: take 2 mL, 3 times per day on an empty stomach.
Use consistently for at least 2 months
Use for a minimum of 2 months to see beneficial effects.
Consult a practitioner if pregnant, breastfeeding, or on certain medications
Do not use if you are pregnant or breastfeeding. Consult a healthcare practitioner prior to use if you are taking blood thinners, protease inhibitors, cardiac glycosides such as digitalis/digoxin, or blood pressure medication, or if you have diabetes.
What the research says about Hawthorn, Garlic, Linden and Motherwort
Educational summaries of published research on this formula's herbs generally; not product-specific claims. Orange Naturals Heart Health Tincture's own authorized use under NPN 80036773 is that it is traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
A 6-month randomized trial found hawthorn provided no additional symptom or functional benefit when added to standard heart failure therapy
In the HERB-CHF trial, 120 patients with NYHA class II-III chronic heart failure taking conventional medical therapy were randomized to hawthorn 450 mg twice daily or placebo for 6 months. There were no significant differences between groups in 6-minute walk distance, quality of life, functional capacity, or measures of oxidative stress and inflammation - though a modest difference in left ventricular ejection fraction favoured hawthorn. More adverse events (mostly non-cardiac) were reported in the hawthorn group.
Human RCT (n=120)A large 2-year multicenter trial found hawthorn extract did not significantly reduce cardiac events on top of standard heart failure treatment
In the SPICE trial, 2,681 patients with NYHA class II-III chronic heart failure and reduced ejection fraction were randomized to hawthorn extract WS 1442 (900 mg/day) or placebo for 24 months, added to optimal standard medication. The primary endpoint (time to first cardiac event) was not significantly different between groups, though a subgroup with less severely reduced ejection fraction showed a significant 39.7% reduction in sudden cardiac death with hawthorn.
Human RCT (n=2,681)An evidence-based review concluded a specific hawthorn extract has a favorable safety profile and can improve functional capacity in heart failure
This benefit-risk review of hawthorn extract WS 1442 summarized nonclinical studies showing positive inotropic, antiarrhythmic and myocardial-protective properties, and randomized controlled trials in heart failure patients demonstrating increased functional capacity, reduced disabling symptoms and improved quality of life. Clinical trials with over 1,300 patients exposed, including a 2-year mortality study, showed a favorable safety profile with no observed drug interactions.
Evidence-Based ReviewA 2025 meta-analysis of 6 randomized trials found hawthorn clinically significantly reduced systolic blood pressure in hypertension
Pooling 6 randomized, placebo-controlled trials (428 participants) over 10 weeks to 6 months, hawthorn significantly decreased systolic blood pressure (mean difference -6.65 mmHg) and showed a non-significant reduction in diastolic blood pressure, across doses of 250-1200 mg/day. The authors called for larger, well-designed trials to establish optimal dosing.
Meta-Analysis (6 RCTs, n=428)A dose-response crossover trial found no evidence that higher hawthorn doses produced greater blood-vessel dilation in prehypertensive adults
In 21 prehypertensive or mildly hypertensive adults given placebo or hawthorn extract (1000, 1500 or 2500 mg, standardized to 50 mg oligomeric procyanidin per 250 mg) in a 4-period crossover design, there was no evidence of a dose-response effect on brachial artery flow-mediated dilation or on blood pressure - an honest null finding suggesting any blood-pressure effect of hawthorn is not driven by a simple nitric-oxide dose relationship.
Human RCT, Crossover (n=21)A rat study found hawthorn fruit extract lowered blood pressure partly by regulating bile-acid and inflammation-related pathways
In spontaneously hypertensive rats treated with hawthorn extract or its compound hyperoside for 7 weeks, blood pressure was significantly reduced and aortic vascular injury improved. Serum metabolomics identified the primary bile-acid biosynthesis pathway as a key mechanism, with expression changes in genes involved in bile-acid metabolism and inflammation (including FXR, TGR5, ET-1, NOS3 and TNF-alpha) in the treated groups.
Preclinical Study (rat)An updated meta-analysis of 20 trials found garlic lowered blood pressure, with a larger effect in hypertensive individuals
Pooling 20 randomized controlled trials (970 participants), garlic supplements reduced systolic blood pressure by an average of 5.1 mmHg and diastolic blood pressure by 2.5 mmHg compared to placebo. In the subgroup with hypertension at baseline, the effect was substantially larger - systolic blood pressure fell by 8.7 mmHg and diastolic by 6.1 mmHg.
Meta-Analysis (20 RCTs, n=970)An earlier meta-analysis found garlic preparations reduced blood pressure, with the largest effect in hypertensive subgroups
This systematic review and meta-analysis of 11 trials suitable for pooling found garlic reduced systolic blood pressure by 4.6 mmHg overall compared to placebo, with a larger reduction of 8.4 mmHg for systolic and 7.3 mmHg for diastolic blood pressure in the hypertensive subgroup specifically. A significant association was found between baseline blood pressure and the size of the reduction.
Systematic Review & Meta-Analysis (11 trials)A systematic review found garlic may lower blood pressure in hypertensive individuals, but called the evidence not strong
Reviewing 9 double-blind randomized trials (482 individuals) with at least 4 weeks of follow-up, this analysis found systolic and diastolic blood pressure were more effectively reduced with garlic than placebo, but heterogeneity across trials was high and effect sizes shrank when restricted to higher-quality trials - an honest, hedged conclusion that a well-powered, longer trial is still needed to confirm the finding.
Systematic Review & Meta-Analysis (9 RCTs, n=482)A 2026 comprehensive meta-analysis of 108 trials found garlic significantly improved multiple cardiovascular risk markers
Pooling 108 randomized controlled trials (7,137 participants), garlic intake significantly improved triglycerides, total and LDL cholesterol, HDL cholesterol, fasting blood glucose, insulin resistance, systolic and diastolic blood pressure, and markers of oxidative stress and inflammation (CRP, TNF-alpha). Garlic did not significantly affect apolipoprotein levels, liver enzymes (ALT), interleukin-6, body weight or BMI.
Meta-Analysis (108 RCTs, n=7,137)A meta-analysis in coronary artery disease patients found garlic reduced total cholesterol but not triglycerides or LDL/HDL levels
This meta-analysis of 6 randomized trials in patients with coronary artery disease found garlic consumption significantly reduced total cholesterol (mean difference -16.32 mg/dL), but found no significant effect on triglycerides, HDL cholesterol or LDL cholesterol - an honest, mixed result showing garlic's lipid benefit in this population was limited to total cholesterol.
Meta-Analysis (6 RCTs)A dose-response trial found only higher doses of aged garlic extract significantly lowered blood pressure in treated hypertensives
In 79 patients with uncontrolled hypertension already on antihypertensive medication, a 12-week randomized trial of aged garlic extract (1, 2 or 4 capsules daily) found the 2-capsule dose significantly reduced systolic blood pressure by 11.8 mmHg versus placebo, while the 4-capsule dose reached only borderline significance and the 1-capsule dose showed no significant difference - a nuanced, dose-dependent finding rather than a uniform benefit.
Human RCT, Dose-Response (n=79)A 2024 review identified motherwort alongside hawthorn and garlic as candidate herbs for managing cardiovascular disease
This review examined white mulberry, sea-buckthorn, garlic, lily of the valley, motherwort and hawthorn as potential herbal options for cardiovascular disorders, drawing on in vitro and ex vivo animal studies. The authors noted ongoing interest in herbal options that could be used alongside standard treatments such as diuretics, beta blockers and ACE inhibitors, while cautioning that most of the underlying evidence for these six herbs remains preclinical.
Review (in vitro/ex vivo)A 2025 phytochemistry study noted motherwort's long-recognized cardioactivity and identified new active compounds relevant to metabolic health
This study of Leonurus cardiaca (motherwort), described as 'known in Europe for its cardioactivity,' isolated several phenylethanoid glycosides and iridoids and screened them for activity on PPAR receptors, which help control lipid metabolism. The iridoid compound 7-chloro-6-desoxy-harpagide showed significant activity on the PPAR-delta receptor, a target of interest for metabolic syndrome, though this was a laboratory receptor-binding study, not a clinical trial.
Preclinical Study (receptor assay)A classic study identified calming flavonoid compounds in linden flowers that act on the same receptors as anti-anxiety medications
Testing extracts of Tilia tomentosa (a linden species) in a receptor-binding assay, researchers identified kaempferol and an unidentified flavonoid-type fraction that bound benzodiazepine receptors. When given to mice, the active fraction produced a clear anxiolytic effect on two validated behavioral tests without affecting general movement - a mechanistic explanation for linden's traditional use as a calming, nervine herb.
Preclinical Study (mouse)A randomized trial found a different polyherbal formula improved diastolic heart function in hypertensive patients
In a randomized, placebo-controlled trial, 35 hypertensive patients with left ventricular diastolic dysfunction received a polyherbal Unani formulation (a different multi-herb combination than this product) or placebo for 8 weeks. The treatment group showed significant improvement in dyspnea and diastolic function, and highly significant improvement in easy fatigability, versus placebo. As a different combination formula, results reflect that specific blend, not this product.
Human RCT (n=35)A randomized trial found another polyherbal preparation lowered cholesterol and triglycerides about as well as a statin drug
74 adults with dyslipidaemia were randomized to a different Unani polyherbal preparation (10 g/day) or the statin drug atorvastatin (20 mg/day) for 90 days. Both groups saw significant reductions in total cholesterol, triglycerides and LDL cholesterol, with no significant difference between the two treatments, and both were well tolerated. As a different combination formula, this result reflects that specific polyherbal blend, not this product's own formula.
Human RCT (n=74)A systematic review found many herbal interventions target multiple pathways involved in cardiovascular disease
This systematic review of herbal interventions for cardiovascular disease management found that herbs commonly act through anti-inflammatory, antioxidant, anti-thrombotic, anti-hypertensive and lipid-lowering mechanisms, with some also improving endothelial function and nitric oxide production. The authors emphasized that larger, rigorous clinical trials and attention to herb-drug interactions are still needed before herbal combination therapies can be broadly recommended alongside conventional treatment.
Systematic ReviewA pharmacological review found standardized hawthorn extracts show cardiotonic and vaso-protective properties beyond heart failure
This review of standardized hawthorn leaf-and-flower extracts, drawing on clinical trials involving more than 4,000 patients, summarized evidence for benefit in mild chronic heart failure alongside preclinical findings of cardio- and vaso-protective properties - including potential relevance to endothelial dysfunction, atherosclerosis and coronary heart disease - while noting most robust clinical evidence remains concentrated in heart failure specifically.
ReviewA broad review of antihypertensive medicinal herbs included both hawthorn and garlic among plants studied for blood pressure regulation
This review surveyed the traditional use, phytochemical constituents and pharmacological evidence for herbs used to help normalize hypertension, including Crataegus (hawthorn), Allium sativum (garlic), hibiscus, ginger, and several others, noting herbal medicines are used by an estimated 80% of the world's population for major health concerns including blood pressure management.
ReviewA rat study found a hawthorn fruit extract reduced oxidative stress and improved blood-vessel function in glucose-induced hypertension
In rats made hypertensive through glucose loading, 21 days of a hawthorn-related fruit extract prevented the rise in systolic blood pressure, reduced markers of oxidative stress, and improved endothelium-dependent vascular reactivity compared to untreated hypertensive rats, with no evidence of acute toxicity at the doses tested.
Preclinical Study (rat)A review found theoretical hawthorn herb-drug interactions have not been commonly observed in practice, though safety monitoring should continue
This review of hawthorn's use in cardiovascular disease found that clinical trials, while inconsistent in design, have been largely consistent in showing positive outcomes, and that theoretical adverse herb-drug interactions have not been widely experienced in practice - adverse reactions were infrequent and mild even at higher doses. The review also discussed an earlier retrospective analysis suggesting a possible negative signal for long-term hawthorn use in heart failure prognosis, underscoring that ongoing safety monitoring is still warranted.
ReviewA pharmacovigilance analysis of over 1,500 real-world adverse-event reports found hawthorn products are generally well tolerated
Analyzing 1,527 individual case safety reports from the WHO's global VigiBase and 13 additional reports from the Netherlands' Lareb database (1970-2023) for Crataegus (hawthorn)-containing products, the most frequently reported adverse reactions involved the gastrointestinal, skin, cardiac and nervous systems - mostly minor. Of 277 reports where a single-herb hawthorn product was the only suspected cause, 12.6% were graded as serious, supporting cautious but reassuring real-world safety data.
Pharmacovigilance Analysis (1,527 reports)A perioperative medicine review flagged garlic, alongside ginger and gingko, as a dietary supplement with a real bleeding-risk consideration
This review of antithrombotic medication management in surgical patients discussed dietary supplements including garlic, ginger and gingko alongside prescription blood thinners and antiplatelet drugs, noting these supplements carry their own bleeding-risk considerations that clinicians should factor into perioperative planning - consistent with this product's own labeled caution to consult a healthcare practitioner before use if taking blood thinners.
Clinical ReviewFrequently asked questions
What is Orange Naturals Heart Health Tincture and what does it do?
It's a liquid tincture combining Hawthorn (156.25 mg), Garlic (31.25 mg), Linden (25 mg) and Motherwort (25 mg) per mL. Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
How do I take it?
Adults take 2 mL, 3 times per day on an empty stomach. Use for a minimum of 2 months to see beneficial effects.
Who should not use this product?
Do not use if you are pregnant or breastfeeding.
Who should consult a healthcare practitioner before using it?
Consult a healthcare practitioner prior to use if you are taking any medication including blood thinners, protease inhibitors or cardiac glycosides such as digitalis/digoxin, or blood pressure medication, or if you have diabetes, or if symptoms persist or worsen.
What are the non-medicinal ingredients?
40% grain alcohol and purified water.
How much is in one bottle?
Each bottle contains 100 mL (3.38 fl oz) of tincture.
Is this a Health Canada licensed product?
Yes - it is licensed as a Natural Health Product under NPN 80036773.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Support your heart with a 4-herb traditional blend
Get Orange Naturals Heart Health Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80036773. Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults. Do not use if you are pregnant or breastfeeding. Consult a healthcare practitioner prior to use if you are taking any medication including blood thinners, protease inhibitors or cardiac glycosides such as digitalis/digoxin, or blood pressure medication, or if you have a medical condition including diabetes, or if symptoms persist or worsen. The research summaries on this page concern hawthorn, garlic, linden and motherwort generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner if symptoms persist or worsen. Consult a healthcare practitioner prior to use if you are taking any medication including blood thinners, protease inhibitors or cardiac glycosides such as digitalis/digoxin, or blood pressure medication, or if you have a medical condition including diabetes. Do not use if seal is broken. Keep out of reach of children. Contra-Indications: Do not use if you are pregnant or breastfeeding. Known Adverse Reactions: Hypersensitivity (e.g. allergy) has been known to occur; in which case, discontinue use.
Indications
Recommended Use or Purpose: Traditionally used in Herbal Medicine to help maintain and support cardiovascular health in adults.
Ingredients
Medicinal Ingredients (each mL contains): Hawthorn (fruit, Crataegus laevigata), 1:4 extract, 156.25 mg (0.156 g DHE). Garlic (bulb, Allium sativum), 1:4 extract, 31.25 mg (0.031 g DHE), organically grown. Linden (flower, Tilia cordata), 1:5 extract, 25 mg (0.025 g DHE). Motherwort (herb, Leonurus cardiaca), 1:5 extract, 25 mg (0.025 g DHE), organically grown. Non-medicinal Ingredients: 40% grain alcohol, purified water.
Directions
Recommended Dose (Adults): Take 2 mL, 3 times per day on an empty stomach. Use for a minimum of 2 months to see beneficial effects.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.