Orange Naturals American Ginseng Tincture | 100mL
Visit the Orange Naturals Store| Brand | Orange |
| Serving | 3 mL, 3 times per day |
| Licensed Natural Health Product | NPN 80030443 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- SUPPORTS HEALTHY GLUCOSE LEVELS: Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels.
- RELIEVES NERVOUSNESS: Traditionally used in Herbal Medicine to help relieve nervousness, as a mild sedative.
- CALMS AND IMPROVES DIGESTION: Traditionally used in Herbal Medicine to help relieve nervous dyspepsia and to help digestion in cases of nervousness or stress.
- HELPS MAINTAIN A HEALTHY IMMUNE SYSTEM: Traditionally used in Herbal Medicine to help maintain a healthy immune system.
- WILDCRAFTED AMERICAN GINSENG ROOT, 1:4 EXTRACT: Made from wildcrafted American ginseng root (Panax quinquefolius), extracted at a 1:4 ratio.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80030443.
Product Description
American Ginseng Tincture - Traditional Glucose, Immune & Nervous System Support
Orange Naturals American Ginseng Tincture delivers 250 mg of wildcrafted American Ginseng (root, Panax quinquefolius) per mL, extracted at a 1:4 ratio in a base of grain alcohol and purified water. Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels, American Ginseng is also traditionally used in Herbal Medicine to help maintain a healthy immune system, to help relieve nervous dyspepsia and digestion in cases of nervousness or stress, and to help relieve nervousness as a mild sedative. This 100 mL naturopathic tincture is licensed as a Natural Health Product. Licensed Natural Health Product NPN 80030443.
Teinture de Ginseng américain d'Orange Naturals offre 250 mg de Ginseng américain sauvage (racine, Panax quinquefolius) par mL, extrait selon un ratio de 1:4 dans une base d'alcool de grain et d'eau purifiée. Utilisé en phytothérapie comme thérapie de soutien pour la promotion de taux de glycémie sains, le Ginseng américain est également utilisé traditionnellement en phytothérapie pour aider à maintenir un système immunitaire sain, pour aider à soulager la dyspepsie nerveuse et la digestion en cas de nervosité ou de stress, et pour aider à soulager la nervosité comme sédatif léger. Cette teinture naturopathique de 100 mL est homologuée comme produit de santé naturel. NPN 80030443.
A Traditional Root, Modern Tincture Format
250 mg American Ginseng (wildcrafted root, Panax quinquefolius), 1:4 extract - fast-absorbing liquid format, 3 mL 3 times daily
250 mg American Ginseng per mL
Each mL delivers a full 250 mg dose of wildcrafted American Ginseng root (Panax quinquefolius), extracted at a 1:4 ratio - take 3 mL, 3 times per day.
Fast-Absorbing Tincture Format
As a liquid tincture, American Ginseng can begin absorbing quickly, offering a fast-acting alternative to capsules or tablets.
Advanced Ingredients, Superior Results
Panax quinquefolius (American Ginseng) is a North American root distinct from Asian/Korean ginseng (Panax ginseng), studied for its role in post-meal blood sugar support, immune function, cognitive performance and cardiovascular health. Here is what the wider research explores.
American Ginseng (wildcrafted root, Panax quinquefolius)
A North American root long used in Herbal Medicine, studied for its role in post-meal blood sugar support, immune function and cognitive performance - botanically distinct from Asian/Korean ginseng (Panax ginseng).
250 mg per mL, 1:4 extract
Orange Naturals American Ginseng Tincture: Supplement Facts
Each mL contains:
- American Ginseng (wildcrafted root, Panax quinquefolius), 1:4 extract250 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: 40% grain alcohol, purified water.
Recommended Use or Purpose: Traditionally used in Herbal Medicine to help maintain a healthy immune system. Traditionally used in Herbal Medicine to help relieve nervous dyspepsia and to help digestion in cases of nervousness and/or stress. Traditionally used in Herbal Medicine to help relieve nervousness, as a mild sedative. Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels.
Recommended Dose (Adults): Take 3 mL, 3 times per day.
Cautions and Warnings: Consult a healthcare practitioner prior to use if you have diabetes. Consult a healthcare practitioner prior to use if you are taking blood thinners or digoxin. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque mL contient :
- Ginseng américain (racine sauvage, Panax quinquefolius), extrait 1:4250 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Alcool de grain à 40 %, eau purifiée.
Usage ou fins recommandés : Utilisé traditionnellement en phytothérapie pour aider à maintenir un système immunitaire sain. Utilisé traditionnellement en phytothérapie pour aider à soulager la dyspepsie nerveuse et pour aider à la digestion en cas de nervosité ou de stress. Utilisé traditionnellement en phytothérapie pour aider à soulager la nervosité, comme sédatif léger. Utilisé en phytothérapie comme thérapie de soutien pour la promotion de taux de glycémie sains.
Posologie recommandée (adultes) : Prendre 3 mL, 3 fois par jour.
Mises en garde : Consulter un praticien de la santé avant d'en faire l'usage si vous avez du diabète. Consulter un praticien de la santé avant d'en faire l'usage si vous prenez des anticoagulants ou de la digoxine. Garder hors de la portée des enfants.
NPN 80030443
Support glucose, immune & nervous system balance with American Ginseng
Get Orange Naturals American Ginseng Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals American Ginseng Tincture
250 mg of American Ginseng (wildcrafted root, Panax quinquefolius) per mL, 1:4 extract - a traditional root in a fast-absorbing tincture format.
250 mg American Ginseng per mL
Each mL delivers a full 250 mg dose of wildcrafted American Ginseng root (Panax quinquefolius), extracted at a 1:4 ratio.
Supports healthy glucose levels
Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels.
Fast-absorbing liquid tincture
Take 3 mL, 3 times per day - a fast-acting alternative to capsules.
Made in Canada, Health Canada licensed
Formulated by Orange Naturals and licensed as a Natural Health Product. NPN 80030443.
Inside every mL
250 mg American Ginseng (wildcrafted root, Panax quinquefolius), 1:4 extract, per mL - take 3 mL, 3 times per day. Non-medicinal ingredients: 40% grain alcohol and purified water.
How to use it
Take 3 mL, 3 times daily
Adults: take 3 mL, 3 times per day.
Use the dropper for accurate dosing
Each 100 mL bottle is designed for precise, drop-by-drop dosing directly into the mouth or in a small amount of water.
Consult a practitioner if you have diabetes or take blood thinners or digoxin
Consult a healthcare practitioner prior to use if you have diabetes, or if you are taking blood thinners or digoxin.
What the research says about American Ginseng
Educational summaries of published research on Panax quinquefolius generally; not product-specific claims. Orange Naturals American Ginseng Tincture's own authorized use under NPN 80030443 is that it is used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels, and traditionally used to help maintain a healthy immune system, help relieve nervous dyspepsia and digestion in cases of nervousness or stress, and help relieve nervousness as a mild sedative.
A crossover study found American ginseng reduced post-meal blood sugar spikes in both non-diabetic volunteers and people with type 2 diabetes
Ten non-diabetic adults and nine adults with type 2 diabetes took 3 g of American ginseng or a matched placebo either 40 minutes before or together with a 25 g oral glucose challenge, on separate occasions. In non-diabetic subjects, ginseng only reduced the post-meal blood sugar rise when taken 40 minutes before the challenge; in subjects with type 2 diabetes, it worked whether taken before or with the challenge, reducing the area under the glycemic curve by 18-22%. The authors noted that, to avoid unintended low blood sugar, it may be important to take American ginseng with a meal rather than well before it.
Human Trial (n=19)An 8-week crossover trial found American ginseng added to standard diabetes treatment improved blood sugar, blood pressure and cholesterol markers
24 people with type 2 diabetes added 3 g/day of American ginseng extract or placebo to their usual treatment for 8 weeks each in a double-blind crossover design. Compared with placebo, American ginseng significantly reduced HbA1c (-0.29%) and fasting blood glucose (-0.71 mmol/L), lowered systolic blood pressure by 5.6 mmHg, increased a marker of healthy blood vessel function, and improved LDL cholesterol markers - with no adverse effect on liver or kidney safety measures.
Human RCT (n=24, crossover)A review by the same research group concluded American ginseng improves post-meal blood sugar control, but flagged real product-to-product variability as a limitation
Summarizing the clinical evidence on American ginseng and type 2 diabetes, this review concluded American ginseng improves glycemic control by increasing post-meal insulin and reducing the post-meal glucose response, positioning it as the best-studied herbal option for this purpose - while cautioning that high, uncontrolled variability in the ginsenoside content of over-the-counter ginseng products can translate into inconsistent real-world effects, and arguing for standardized extracts.
ReviewA 4-month randomized trial of 279 adults found a North American ginseng extract reduced the number, severity and duration of colds
Adults with a history of frequent colds took 2 capsules/day of a poly-furanosyl-pyranosyl-saccharide-rich North American ginseng root extract or placebo for 4 months starting at the onset of flu season. The ginseng group had fewer colds per person, a smaller proportion with 2 or more verified colds during the study (10.0% vs 22.8%), lower total symptom scores, and fewer total days with cold symptoms (10.8 vs 16.5 days) than the placebo group.
Human RCT (n=279)A trial in community-dwelling seniors found a North American ginseng extract cut respiratory illness during the peak cold-and-flu months by about half
43 adults aged 65 and older took 2 capsules/day of COLD-fX (CVT-E002, a North American ginseng root extract) or placebo for 4 months, with a flu shot administered after the first month. Illness rates were similar between groups for the first two months, but during the final two months significantly fewer ginseng-group participants reported acute respiratory illness (32% vs 62%), with a much shorter average symptom duration (5.6 vs 12.6 days).
Human RCT (n=43)A systematic review found North American ginseng shortened cold duration when taken preventatively, but the evidence for reducing how often colds occur was inconclusive
Reviewing 5 randomized trials (747 participants, all using North American ginseng) for the prevention of the common cold, the authors found a tendency toward fewer colds in the ginseng group that did not reach statistical significance across trials, but a significant 6.2-day reduction in the duration of colds or acute respiratory infections when ginseng was taken preventatively for 8 to 16 weeks - an honest, mixed verdict rather than a uniformly positive one.
Systematic Review (5 RCTs, n=747)A crossover trial found a single dose of American ginseng improved working memory and calmness within hours of taking it
In a randomized, double-blind, placebo-controlled crossover study, healthy adults took a single dose of American ginseng extract or placebo and completed cognitive testing at intervals afterward. The extract improved performance on a working memory task and increased self-rated calmness compared with placebo, pointing to a measurable acute cognitive effect from a single dose.
Human RCT (crossover)A single dose of American ginseng improved working memory performance in healthy middle-aged adults
Healthy adults in midlife took a single dose of American ginseng (Panax quinquefolius) extract or placebo in a randomized, double-blind study, with working memory and other cognitive tasks assessed afterward. The ginseng dose produced measurable improvements in working memory performance compared with placebo.
Human RCTA brain-wave study found American ginseng altered a measurable marker of attention during cognitive testing
Using steady-state visually evoked potentials (an electrical brain response measured during a task) alongside standard cognitive tests, this randomized, double-blind, placebo-controlled study found a single dose of Panax quinquefolius extract changed this attention-related brain signal during cognitive performance compared with placebo, offering a physiological correlate for the cognitive effects seen in other American ginseng trials.
Human RCTA pilot dose-finding trial found an early signal of benefit for American ginseng in cancer-related fatigue
This NCCTG pilot trial (N03CA) randomized cancer patients experiencing fatigue to different doses of Panax quinquefolius or placebo in a double-blind design, aiming to identify an effective dose and gather preliminary efficacy data ahead of a larger confirmatory trial.
Human Pilot RCTA 364-patient Phase III trial found American ginseng significantly reduced cancer-related fatigue at 8 weeks, but not yet at 4 weeks
This large, multisite, double-blind trial (N07C2) randomized fatigued cancer survivors to 2,000 mg per day of American ginseng or placebo for 8 weeks. The improvement in fatigue scores was not yet statistically significant at 4 weeks (P=.07) but reached significance by 8 weeks, with a larger benefit seen in patients still undergoing active cancer treatment; toxicity/side-effect reports did not differ meaningfully between arms - an honest, time-dependent finding rather than an immediate one.
Human RCT (n=364)A meta-analysis of 7 trials found ginseng produced only a modest, borderline-significant reduction in cancer-related fatigue
Pooling seven randomized controlled trials of ginseng (including American ginseng trials among the studies pooled) for cancer-related fatigue, this meta-analysis found a modest overall reduction in fatigue (standardized mean difference -0.21, 95% CI -0.42 to 0.00 - a confidence interval that just touches zero), alongside small improvements in physical and emotional well-being - a fair, unhedged read of the pooled evidence rather than a strong endorsement.
Meta-Analysis (7 RCTs)A 12-week trial found American ginseng improved arterial stiffness and lowered systolic blood pressure in people with diabetes and hypertension
64 people with well-controlled type 2 diabetes and hypertension added 3 g/day of American ginseng extract or placebo to their usual treatment for 12 weeks. Compared with placebo, American ginseng significantly reduced arterial stiffness (augmentation index, -5.3%) and systolic blood pressure (-11.7%), with no effect on diastolic blood pressure.
Human RCT (n=64)A same-day trial found North American ginseng had a neutral acute effect on blood pressure in people with hypertension
16 people with hypertension took 3 g of one of six different North American ginseng root batches (chosen to reflect the range of quality and ginsenoside content on the market) or placebo, with blood pressure monitored for over 2 hours afterward. Overall, none of the ginseng batches differed meaningfully from placebo in their effect on blood pressure, addressing an earlier observational concern that ginseng might raise blood pressure.
Human RCT (n=16)A 12-week crossover trial found long-term North American ginseng use had no effect on 24-hour blood pressure or kidney function
52 people with hypertension took 3 g/day of North American ginseng or placebo for 12 weeks each in a crossover design, with 24-hour ambulatory blood pressure monitoring and a kidney-function blood marker measured at each visit. Ginseng showed a neutral effect on all measured blood pressure parameters and did not affect the kidney marker, extending the same research group's earlier single-dose finding to long-term use.
Human RCT (n=37 completers, crossover)A controlled trial found American ginseng measurably reduced the blood-thinning effect of warfarin
20 healthy volunteers received warfarin for 3 days in weeks 1 and 4 of a 4-week study, with American ginseng or placebo added starting in week 2. After 2 weeks of ginseng, peak INR (a measure of blood-clotting time) and plasma warfarin levels were both significantly lower than with placebo - confirming that American ginseng weakens warfarin's anticoagulant effect, the real evidence behind this product's own caution for people taking blood thinners.
Human RCT (n=20)A systematic review of herb-warfarin interaction trials found American ginseng specifically altered how warfarin behaves in the body
Reviewing 9 randomized controlled trials on herbal medicine-warfarin interactions, this review found that while several herbs (including ginseng generally, ginger, garlic and cranberry) showed no effect on warfarin's absorption or metabolism, American ginseng specifically altered warfarin's pharmacodynamic effect (how strongly it thins the blood) - a more precise, mechanism-level confirmation of the earlier clinical finding above.
Systematic Review (9 RCTs)A real-world study of older adults found ginseng combined with blood thinners was one of the most common risky supplement-drug combinations
Analyzing interview data from over 5,000 older adults in the Cardiovascular Health Study, this retrospective analysis found that concurrent use of natural health products alongside prescription drugs was common, and that most of the combinations flagged as carrying a significant risk of adverse interaction involved a bleeding risk from ginkgo, garlic, or ginseng taken together with aspirin, warfarin, ticlopidine or pentoxifylline.
Retrospective Study (n=5,052)A lab study found a North American ginseng extract activated immune cells and boosted antibody production in mice
In mouse spleen cells and immune cells (macrophages), a proprietary North American ginseng root extract (CVT-E002) stimulated the growth of B lymphocytes (antibody-producing immune cells), activated macrophages to release more of several immune-signaling proteins (IL-1, IL-6, TNF-alpha and nitric oxide), and increased antibody (IgG) production in treated mice - a preclinical mechanism consistent with this ingredient's traditional immune-support use.
Preclinical Study (mouse/in vitro)A lab study found North American ginseng extract neutralized free radicals and bound metal ions linked to oxidative damage
Tested in cell-free lab assays, a North American ginseng root extract bound iron and copper ions (limiting their ability to drive oxidative damage), scavenged multiple types of free radicals in a dose-dependent way, and protected both a fat emulsion and a brain protein sample from oxidative damage - a foundational preclinical look at the antioxidant mechanisms behind the ingredient's broader reputation.
Preclinical Study (in vitro)An analysis of 25 commercial ginseng products found real, sometimes large batch-to-batch variability in active-compound content
Testing 25 commercial ginseng products (Panax species and Eleutherococcus/Siberian ginseng) purchased from a US health food store, this analysis confirmed every product was correctly labeled by plant species, but found active-compound (ginsenoside/eleutheroside) concentrations varied 15- to 43-fold between products of the same nominal type - underscoring why a fixed, standardized 1:4, 250 mg/mL extract matters for consistent dosing.
Laboratory Analysis (25 products)A review distinguishing the three major ginseng species found each carries its own distinct antimicrobial compound profile
Comparing Asian ginseng (Panax ginseng), American ginseng (Panax quinquefolius) and notoginseng (Panax notoginseng) - the three most commonly used ginseng botanicals worldwide - this review found each species' antimicrobial activity stems from a broadly overlapping but not identical set of ginsenosides, polysaccharides and other compounds, reinforcing that these are related but genuinely distinct plants rather than interchangeable 'ginseng.'
ReviewA clinical review of the OTHER major ginseng species - Asian/Korean ginseng - illustrates why species matters when reading ginseng research
This review covers Panax ginseng (Asian/Korean ginseng) specifically - a different species from the Panax quinquefolius (American ginseng) in this product - describing its own evidence for psychological function, immune function and diabetes-related conditions, and its own caution around concurrent use with warfarin, diabetes medications and certain antidepressants. It is included here only to illustrate the genus's breadth, not as evidence for this product's own species.
ReviewA 2025 review pulled together the human trial evidence specifically for American ginseng's effects on the brain
Synthesizing the human clinical trial literature specifically on Panax quinquefolius (American ginseng) and neurocognitive function - including several of the working-memory and attention studies summarized above - this review characterizes American ginseng as a distinct research subject from Asian ginseng, with its own emerging but still-developing evidence base for acute cognitive effects.
ReviewFrequently asked questions
What is Orange Naturals American Ginseng Tincture and what does it do?
It's a liquid tincture providing 250 mg of American Ginseng (wildcrafted root, Panax quinquefolius), 1:4 extract, per mL. Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels, and traditionally used to help maintain a healthy immune system, help relieve nervous dyspepsia and digestion in cases of nervousness or stress, and help relieve nervousness as a mild sedative.
How do I take it?
Adults take 3 mL, 3 times per day.
Who should consult a healthcare practitioner before using it?
Consult a healthcare practitioner prior to use if you have diabetes, or if you are taking blood thinners or digoxin.
What is American Ginseng traditionally used for?
American Ginseng (Panax quinquefolius) is traditionally used in Herbal Medicine to help maintain a healthy immune system, to help relieve nervous dyspepsia and digestion in cases of nervousness or stress, and to help relieve nervousness as a mild sedative - and is used as supportive therapy for the promotion of healthy glucose levels.
Is American Ginseng the same as Asian/Korean ginseng?
No - American Ginseng (Panax quinquefolius) is a botanically distinct species from Asian/Korean ginseng (Panax ginseng). This product contains only Panax quinquefolius.
What are the non-medicinal ingredients?
40% grain alcohol and purified water.
How much is in one bottle?
Each bottle contains 100 mL (3.38 fl oz) of tincture.
Is this a Health Canada licensed product?
Yes - it is licensed as a Natural Health Product under NPN 80030443.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Support glucose, immune & nervous system balance with American Ginseng
Get Orange Naturals American Ginseng Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80030443. Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels; traditionally used in Herbal Medicine to help maintain a healthy immune system, to help relieve nervous dyspepsia and digestion in cases of nervousness or stress, and to help relieve nervousness as a mild sedative. Consult a healthcare practitioner prior to use if you have diabetes, or if you are taking blood thinners or digoxin. The research summaries on this page concern American ginseng generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner prior to use if you have diabetes. Consult a healthcare practitioner prior to use if you are taking blood thinners or digoxin. Keep out of reach of children.
Indications
Recommended Use or Purpose: Traditionally used in Herbal Medicine to help maintain a healthy immune system. Traditionally used in Herbal Medicine to help relieve nervous dyspepsia and to help digestion in cases of nervousness and/or stress. Traditionally used in Herbal Medicine to help relieve nervousness, as a mild sedative. Used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels.
Ingredients
Medicinal Ingredients (each mL contains): American Ginseng (wildcrafted root, Panax quinquefolius), 1:4 extract, 250 mg (0.25 g DHE). Non-medicinal Ingredients: 40% grain alcohol, purified water.
Directions
Recommended Dose (Adults): Take 3 mL, 3 times per day.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.