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Health Canada NPN 80031172 250 mg Fenugreek (seed, Trigonella foenum-graecum) per mL, 1:4 Extract Made in Canada · Naturopathic Tincture Supports Healthy Glucose Levels & Helps Reduce Elevated Blood Lipid Levels
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Orange Naturals Fenugreek Tincture | 100mL

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BrandOrange
Serving4 mL, 2 times per day
Licensed Natural Health ProductNPN 80031172
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORTS HEALTHY GLUCOSE LEVELS: Traditionally used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels.
  • HELPS REDUCE ELEVATED BLOOD LIPID LEVELS: Used in Herbal Medicine to help reduce elevated blood lipid levels (hyperlipidemia).
  • STIMULATES THE APPETITE: Traditionally used in Herbal Medicine to help stimulate the appetite.
  • AIDS DIGESTION & RELIEVES DYSPEPSIA: Traditionally used in Herbal Medicine as a digestive tonic to aid digestion, and to help relieve dyspepsia and gastritis.
  • ACTS AS A MILD LAXATIVE: Used in Herbal Medicine as a mild laxative.
  • SUPPORTS BREAST MILK PRODUCTION: Traditionally used in Herbal Medicine as a galactogogue to help promote milk production/secretion.
  • TRADITIONAL NUTRITIVE TONIC & EXPECTORANT: Traditionally used in Herbal Medicine as a nutritive tonic, and as an expectorant to help relieve excess mucous of the upper respiratory passages.
  • MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80031172.

Customer Reviews

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Product Description

Fenugreek Tincture - Traditional Glucose, Lipid & Digestive Support

Orange Naturals Fenugreek Tincture

Orange Naturals Fenugreek Tincture delivers 250 mg of organic Fenugreek (seed, Trigonella foenum-graecum) per mL, extracted at a 1:4 ratio in a base of grain alcohol and purified water. Used in Herbal Medicine to support healthy glucose levels and help reduce elevated blood lipid levels, Fenugreek is also traditionally used in Herbal Medicine as a digestive tonic to aid digestion, to help relieve dyspepsia and gastritis, as a mild laxative, to help stimulate the appetite, and as a galactogogue to help promote milk production. This 100 mL naturopathic tincture is licensed as a Natural Health Product. Licensed Natural Health Product NPN 80031172.

Teinture de Fenugrec d'Orange Naturals offre 250 mg de Fenugrec biologique (graine, Trigonella foenum-graecum) par mL, extrait selon un ratio de 1:4 dans une base d'alcool de grain et d'eau purifiée. Utilisée en phytothérapie comme thérapie de soutien pour aider au contrôle du taux de glucose et pour aider à réduire les taux de lipides sanguins élevés, la Fenugrec est également utilisée traditionnellement en phytothérapie comme tonique digestif pour aider à la digestion, pour aider à soulager la dyspepsie et la gastrite, comme laxatif léger, pour aider à stimuler l'appétit, et comme galactogogue pour aider à la production de lait. Cette teinture naturopathique de 100 mL est homologuée comme produit de santé naturel. NPN 80031172.

Fenugreek Tincture lifestyle
Orange Naturals Fenugreek Tincture
250 mg Fenugreek (Trigonella foenum-graecum) per mL · 1:4 Extract

A Traditional Seed, Modern Tincture Format

250 mg Fenugreek (seed, Trigonella foenum-graecum), 1:4 extract - fast-absorbing liquid format, 4 mL 2 times daily

250 mg Fenugreek per mL

Each mL delivers a full 250 mg dose of organic Fenugreek seed (Trigonella foenum-graecum), extracted at a 1:4 ratio - adults (19+) take 4 mL, 2 times per day on an empty stomach, with 250 mL of water per dose.

Fast-Absorbing Tincture Format

As a liquid tincture, Fenugreek can begin absorbing in the mouth, offering a fast-acting alternative to capsules or tablets.

Advanced Ingredients, Superior Results

Trigonella foenum-graecum (Fenugreek) is one of the most widely studied seeds in traditional herbal medicine for metabolic and digestive support, explored for its role in glucose regulation, blood lipid levels, lactation support and traditional digestive-tonic use. Here is what the wider research explores.

Fenugreek (seed, Trigonella foenum-graecum)

A traditional Mediterranean and South Asian seed long used as a digestive tonic and galactogogue, studied for its role in glucose regulation, blood lipid levels and metabolic support.

250 mg per mL, 1:4 extract

Orange Naturals Fenugreek Tincture: Supplement Facts

Orange™Fenugreek Tincture
English

Each mL contains:

  • Fenugreek (seed, Trigonella foenum-graecum), 1:4 extract250 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: 40% grain alcohol, purified water.

Recommended Use or Purpose: Traditionally used in Herbal Medicine to help stimulate the appetite. Traditionally used in Herbal Medicine as a digestive tonic to aid digestion. Traditionally used in Herbal Medicine to help relieve dyspepsia and gastritis. Used in Herbal Medicine as a mild laxative. Traditionally used in Herbal Medicine as an expectorant to help relieve excess mucous of the upper respiratory passages (anti-catarrhal). Traditionally used in Herbal Medicine as a nutritive tonic. Traditionally used in Herbal Medicine as a galactogogue to help promote milk production/secretion. Traditionally used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels. Used in Herbal Medicine to help reduce elevated blood lipid levels (hyperlipidemia).

Recommended Dose (Adults 19 years and older): Take 4 mL, 2 times per day, with 250 mL of water per dose.

Cautions and Warnings: Consult a healthcare practitioner prior to use if you are pregnant. Consult a healthcare practitioner prior to use if you have diabetes. Consult a healthcare practitioner if symptoms persist. Consult a healthcare practitioner if symptoms worsen. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

Français

Chaque mL contient :

  • Fenugrec (graine, Trigonella foenum-graecum), extrait 1:4250 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Alcool de grain à 40 %, eau purifiée.

Usage ou fins recommandés : Utilisé traditionnellement en phytothérapie pour aider à stimuler l'appétit. Utilisé traditionnellement en phytothérapie comme tonique digestif pour aider à la digestion. Utilisé traditionnellement en phytothérapie pour aider à soulager la dyspepsie et la gastrite. Utilisé en phytothérapie comme laxatif léger. Utilisé traditionnellement en phytothérapie comme expectorant pour aider à soulager l'excès de mucus des voies respiratoires supérieures (anticatarrhal). Utilisé traditionnellement en phytothérapie comme tonique nutritif. Utilisé traditionnellement en phytothérapie comme galactogogue pour aider à la production de lait. Utilisé traditionnellement en phytothérapie comme thérapie de soutien pour aider au contrôle du taux de glucose. Utilisé en phytothérapie pour aider à réduire les taux de lipides sanguins élevés (hyperlipidémie).

Posologie recommandée (adultes de 19 ans et plus) : Prendre 4 mL, 2 fois par jour, avec 250 mL d'eau par dose.

Mises en garde : Consulter un praticien de la santé avant l'utilisation si vous êtes enceinte. Consulter un praticien de la santé avant l'utilisation si vous avez le diabète. Consulter un praticien de la santé si les symptômes persistent. Consulter un praticien de la santé si les symptômes s'aggravent. Garder hors de la portée des enfants.

NPN 80031172

250 mg Fenugreek (seed, Trigonella foenum-graecum) per mL, 1:4 Extract100 mL (3.38 fl oz) Dropper BottleUsed in Herbal Medicine to Support Healthy Glucose Levels & Help Reduce Elevated Blood Lipid LevelsTraditionally Used in Herbal Medicine as a Digestive Tonic, Appetite Stimulant & Galactogogue

Support healthy glucose & lipid levels with Fenugreek

Get Orange Naturals Fenugreek Tincture on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why Orange Naturals Fenugreek Tincture

250 mg of Fenugreek (seed, Trigonella foenum-graecum) per mL, 1:4 extract - a traditional seed in a fast-absorbing tincture format.

250 mg Fenugreek per mL

Each mL delivers a full 250 mg dose of organic Fenugreek seed (Trigonella foenum-graecum), extracted at a 1:4 ratio.

Supports healthy glucose & lipid levels

Used in Herbal Medicine to support healthy glucose levels and help reduce elevated blood lipid levels.

Fast-absorbing liquid tincture

Take 4 mL, 2 times per day on an empty stomach - a fast-acting alternative to capsules.

Made in Canada, Health Canada licensed

Formulated by Orange Naturals and licensed as a Natural Health Product. NPN 80031172.

Inside every mL

250 mg Fenugreek (seed, Trigonella foenum-graecum), 1:4 extract, per mL - adults (19+) take 4 mL, 2 times per day on an empty stomach, with 250 mL of water per dose. Non-medicinal ingredients: 40% grain alcohol and purified water.

Fenugreek (seed, Trigonella foenum-graecum) 250 mg per mL, 1:4 extract

How to use it

Take 4 mL, 2 times daily on an empty stomach

Adults (19 years and older): take 4 mL, 2 times per day on an empty stomach, with 250 mL of water per dose.

Use consistently for ongoing support

For support of healthy glucose and blood lipid levels, use consistently as part of a daily routine.

Consult a practitioner if pregnant, diabetic, or if symptoms persist

Consult a healthcare practitioner prior to use if you are pregnant or if you have diabetes, or if your symptoms persist or worsen.

What the research says about Fenugreek

Educational summaries of published research on Trigonella foenum-graecum generally; not product-specific claims. Orange Naturals Fenugreek Tincture's own authorized use under NPN 80031172 is that it is used in Herbal Medicine to support healthy glucose levels and help reduce elevated blood lipid levels, and traditionally used as a digestive tonic, appetite stimulant, mild laxative and galactogogue.

Blood Glucose & Diabetes (Human Trials)

A double-blind trial found fenugreek seed extract improved glycemic control and reduced insulin resistance in new type 2 diabetics

Twenty-five newly diagnosed patients with mild-to-moderate type 2 diabetes were randomized to 1 g/day of hydroalcoholic fenugreek seed extract or usual care (diet and exercise) plus placebo for two months. The fenugreek group showed a significantly lower area under the curve for both blood glucose and insulin during an oral glucose tolerance test, along with improved HOMA-model insulin sensitivity. Serum triglycerides also decreased and HDL cholesterol increased significantly compared to the control group.

Human RCT (n=25)
Gupta, Gupta & Lal, Journal of the Association of Physicians of India (2001)
Blood Glucose & Diabetes (Human Trials)

A continuous glucose monitoring crossover trial found defatted fenugreek seed flakes reduced 24-hour glucose swings in type 2 diabetics

Twenty-one adults with type 2 diabetes followed two 14-day cyclic diets, one including 30 g/day of defatted fenugreek seed flakes, while wearing a continuous glucose monitor. The fenugreek diet significantly reduced both the 24-hour glucose area under the curve and the mean amplitude of glycemic swings compared to the control diet, and also significantly lowered fasting glucose and HbA1c by the end of the 14-day fenugreek period.

Human Crossover Trial (n=21, 15 completed)
Deshpande, Gokhale, Bhaskaran, Gayathri, Abirami, Anjana, Krishnaswamy, Mohan & Sudha, Asia Pacific Journal of Clinical Nutrition (2025)
Blood Glucose & Diabetes (Human Trials)

Fenugreek seeds soaked in hot water reduced fasting blood sugar and triglycerides in type 2 diabetics, but the same seeds mixed with yoghurt did not

Eighteen type 2 diabetic patients took 10 g/day of powdered fenugreek seeds for 8 weeks, either soaked in hot water or mixed with yoghurt. In the group taking fenugreek soaked in hot water, fasting blood sugar fell by 25%, triglycerides by 30%, and VLDL cholesterol by close to a third - but patients who took the same dose mixed into yoghurt showed no significant lab changes, suggesting preparation method affects fenugreek's measurable metabolic benefit.

Human Trial (n=18)
Kassaian, Azadbakht, Forghani & Amini, International Journal for Vitamin and Nutrition Research (2009)
Blood Lipids & Cardiometabolic Markers (Human Trials)

A 114-patient trial found fenugreek seed powder solution significantly improved cholesterol, triglycerides and both LDL and HDL in new type 2 diabetics

Newly diagnosed type 2 diabetic patients took 25 g of fenugreek seed powder solution twice daily for one month, compared to a metformin control group. The fenugreek group's total cholesterol fell 13.6%, triglycerides fell 23.5%, and LDL cholesterol fell 23.4% versus baseline and versus the control group, while HDL cholesterol rose 21.7% - all changes reaching statistical significance, with no significant lipid changes in the control group.

Human Trial (n=114)
Geberemeskel, Debebe & Nguse, Journal of Diabetes Research (2019)
Blood Lipids & Cardiometabolic Markers (Human Trials)

A triple-blind trial found whole fenugreek seeds improved glucose, lipids and adiponectin in type 2 diabetics

In this triple-blind randomized trial, 88 type 2 diabetic patients took 10 g/day of powdered whole fenugreek seeds or a wheat starch placebo for 8 weeks. Compared to placebo, fenugreek significantly lowered fasting blood glucose, HbA1c, insulin, HOMA-IR, total cholesterol and triglycerides, and significantly raised adiponectin (a hormone linked to healthy metabolic function) - though LDL and HDL cholesterol did not change significantly in either group.

Human RCT (n=88)
Rafraf, Malekiyan, Asghari-Jafarabadi & Aliasgarzadeh, International Journal for Vitamin and Nutrition Research (2014)
Blood Lipids & Cardiometabolic Markers (Human Trials)

An 8-week double-blind trial found fenugreek seed extract raised HDL cholesterol in type 2 diabetics, but most other markers did not differ significantly from placebo

Fifty-four adults with type 2 diabetes took three tablets containing 335 mg of fenugreek seed dry extract daily, or a placebo, for 8 weeks. Both groups improved on several measures compared to their own baseline, including insulin, HOMA-IR and triglycerides, but the only marker where fenugreek significantly outperformed placebo directly was HDL cholesterol. The authors suggested a higher dose, longer duration or larger sample might reveal effects on other markers, and called for further trials - an honest, largely null head-to-head result.

Human RCT (n=54)
Chehregosha, Maghsoumi-Norouzabad, Mobasseri, Fakhr & Tarighat-Esfanjani, Journal of Cardiovascular and Thoracic Research (2024)
Meta-Analyses & Systematic Reviews

A meta-analysis of 10 trials found fenugreek safely improved blood glucose and lipid profile in type 2 diabetes and prediabetes

Pooling 10 randomized controlled trials (706 participants) of fenugreek for hyperglycemia, this systematic review and meta-analysis found fenugreek significantly reduced fasting blood glucose, 2-hour post-glucose readings, and HbA1c, though it did not significantly improve HOMA-IR insulin resistance. It also significantly improved total cholesterol, triglycerides and HDL cholesterol, with no significant hepatic or renal toxicity and only mild gastrointestinal side effects reported in some studies.

Meta-Analysis (10 RCTs, n=706)
Kim, Noh, Kim, Choi & Kim, International Journal of Molecular Sciences (2023)
Meta-Analyses & Systematic Reviews

A meta-analysis of 15 trials found fenugreek supplementation significantly improved all four major blood lipid markers

This systematic review and meta-analysis pooled 15 randomized controlled trials (281 fenugreek recipients, 255 controls) measuring the effect of fenugreek on serum lipids. Fenugreek supplementation significantly lowered total cholesterol, LDL cholesterol and triglycerides, and significantly raised HDL cholesterol, with subgroup analysis showing the lipid-lowering effect was even more pronounced in diabetic subjects specifically.

Meta-Analysis (15 RCTs)
Heshmat-Ghahdarijani, Mashayekhiasl, Amerizadeh, Teimouri Jervekani & Sadeghi, Phytotherapy Research (2020)
Meta-Analyses & Systematic Reviews

A meta-analysis of 12 studies found fenugreek reduced fasting blood sugar, HbA1c and both total and LDL cholesterol

Reviewing 12 controlled clinical trials on fenugreek and cardiometabolic risk factors, this meta-analysis found fenugreek seed significantly reduced fasting blood sugar, HbA1c, total cholesterol and LDL cholesterol compared to placebo, though no significant changes were observed in other cardiometabolic parameters measured, such as blood pressure or triglycerides. The authors concluded fenugreek may be useful as an adjuvant therapy for several cardiometabolic risk factors.

Meta-Analysis (12 trials)
Khodamoradi, Khosropanah, Ayati, Chang, Nasli-Esfahani, Ayati & Namazi, Complementary Therapies in Medicine (2020)
Lactation & Galactagogue Use (Human Trials)

A trial found a fenugreek-containing herbal tea increased breast milk volume and helped newborns regain birth weight faster

Sixty-six mother-infant pairs were randomized to a daily fenugreek-containing herbal tea, a placebo tea, or no tea. Mothers who drank the fenugreek tea produced significantly more measured breast milk by the third day after delivery than the placebo or control groups, and their infants lost significantly less of their birth weight and regained it significantly sooner than infants in either comparison group.

Human RCT (n=66 mother-infant pairs)
Turkyilmaz, Onal, Hirfanoglu, Turan, Koc, Ergenekon & Atalay, Journal of Alternative and Complementary Medicine (2011)
Lactation & Galactagogue Use (Human Trials)

A trial in mothers of preterm babies found fenugreek increased milk volume at one week, but the effect did not hold at two weeks

Sixty-eight mothers of preterm newborns took 500 mg fenugreek or placebo capsules three times daily starting on day 5 postpartum. Milk volume was significantly higher in the fenugreek group on day 7, but by day 15 the difference between groups was no longer statistically significant, and prolactin levels, infant weight gain and breastfeeding satisfaction also did not differ significantly - an honest result the authors say needs larger trials to clarify.

Human RCT (n=68)
Rouhi, Hossieni, Khodaie, Mohammad-Alizadeh-Charandabi & Mirghafourvand, Current Drug Research Reviews (2025)
Lactation & Galactagogue Use (Human Trials)

A Cochrane review found the evidence for fenugreek and other natural galactagogues increasing breast milk is very uncertain

This Cochrane systematic review pooled 41 trials (3,005 mothers) on oral galactagogues, including 27 studies of natural options such as fenugreek, ginger, moringa and fennel. While subgroup analyses suggested natural galactagogues including fenugreek may benefit infant weight and milk volume for some mothers, the overall certainty of evidence was rated low to very low due to substantial heterogeneity between studies, imprecise measurements and incomplete reporting - the reviewers concluded well-designed, high-quality trials are urgently needed before firm conclusions can be drawn.

Systematic Review (Cochrane, 41 RCTs, n=3005)
Foong, Tan, Foong, Marasco, Ho & Ong, Cochrane Database of Systematic Reviews (2020)
Traditional Digestive Use, Appetite & GI Research

A 6-week trial found a fenugreek seed extract selectively reduced fat consumption in overweight men

Thirty-nine healthy overweight men completed a double-blind, placebo-controlled trial of a fixed-dose fenugreek seed extract taken daily for 6 weeks. Compared to placebo, the fenugreek group significantly reduced the proportion of daily energy intake coming from fat, and showed a significant decrease in the insulin-to-glucose ratio - though no significant effect was seen on body weight or on appetite/satiety questionnaire scores.

Human RCT (n=39)
Chevassus, Gaillard, Farret, Costa, Gabillaud, Mas, Dupuy, Michel, Cantie, Renard, Galtier & Petit, European Journal of Clinical Pharmacology (2010)
Traditional Digestive Use, Appetite & GI Research

A narrative review of natural ingredients for digestive complaints found only limited scientific evidence specifically for fenugreek

Reviewing 16 human clinical studies across nine nutritional ingredients marketed for upper gastrointestinal complaints like dyspepsia and heartburn, the authors found robust evidence for ginger and for a peppermint-caraway oil combination, and moderate evidence for melatonin and marine alginate - but rated fenugreek, alongside galactomannan and zinc-carnosine, as having only limited scientific substantiation for these uses so far, an honest assessment that calls for further well-controlled dose-response trials.

Narrative Review (16 human studies)
Schulz, Ahuja & Slavin, Nutrients (2022)
Traditional Digestive Use, Appetite & GI Research

A rat study found fenugreek seed extract protected the stomach and intestinal lining's protective mucus layer during induced ulceration

In rats with chemically or stress-induced gastric and duodenal ulcers, researchers measured the sugar-protein components of the protective mucus layer lining the stomach and intestinal wall. Ulceration disrupted the normal composition of this protective mucus layer, but administering fenugreek extract to ulcerated animals showed a protective effect on the mucus layer of both the stomach and duodenum, supporting fenugreek's traditional use as a digestive-soothing agent.

Preclinical Study (rat)
Khil'ko, Iakubtsova, Preobrazhens'ka & Ostapchenko, Fiziolohichnyi Zhurnal (2013)
Phytochemistry & Mechanisms

A review identified diosgenin, 4-hydroxyisoleucine and fiber as fenugreek's three best-characterized active compounds behind its metabolic effects

This review examined the biologic mechanisms of fenugreek's three most intensively studied bioactive constituents - the steroidal saponin diosgenin, the amino acid derivative 4-hydroxyisoleucine, and the plant's dietary fiber - each shown in various studies to favorably influence glucose tolerance, inflammation, insulin action, liver function and blood lipids, though the authors noted that fenugreek's definitive role as a therapeutic agent in metabolic disease is not yet fully established.

Review
Fuller & Stephens, Advances in Nutrition (2015)
Phytochemistry & Mechanisms

A lab study found fenugreek's compound 4-hydroxyisoleucine improved glucose uptake and reduced inflammation in insulin-resistant fat cells

Mouse fat cells (3T3-L1 adipocytes) made insulin-resistant with high glucose exposure showed a 63% drop in insulin-stimulated glucose uptake and elevated inflammatory TNF-alpha. Treating these cells with 4-hydroxyisoleucine, one of fenugreek's characteristic active compounds, restored glucose transport by 35-60% depending on dose and significantly reduced TNF-alpha production, suggesting a specific cellular mechanism behind fenugreek's traditional glucose-supportive reputation.

Preclinical Study (mouse cell line)
Yu, Wu, Lu, Xie, Zheng, Qin, Gao, Du & Jian, Chinese Journal of Integrated Traditional and Western Medicine (2013)
Phytochemistry & Mechanisms

A broad review positioned diosgenin, fenugreek's key steroidal saponin, as a promising compound against several chronic diseases

This review compiled the literature on diosgenin, the steroidal saponin phytochemical richly present in fenugreek seed, across in vitro, in vivo and clinical research. Diosgenin was found to modulate several important cellular signaling pathways implicated in cardiovascular disease, cancer, nervous system disorders, asthma, arthritis and diabetes, with the compound generally showing a favorable safety and bioavailability profile across the studies reviewed.

Review
Parama, Boruah, Yachna, Rana, Banik, Harsha, Thakur, Dutta, Arya, Mao, Ahn & Kunnumakkara, Life Sciences (2020)
Safety, Pregnancy & Drug-Interaction Research

A case report found fenugreek taken by mothers during labour gave newborns a maple-syrup-like odour, causing a false alarm for a serious metabolic disease

Fenugreek, maple syrup, and the urine of infants with maple syrup urine disease (MSUD) all share a distinctive odour from a shared aroma compound, sotolone. This case report describes newborn infants developing a maple-syrup-like smell after their mothers ingested fenugreek during labour, leading physicians to falsely suspect the serious genetic condition MSUD before the fenugreek explanation was identified - a real, if benign, reason to disclose fenugreek use around the time of delivery.

Case Report
Korman, Cohen & Preminger, Journal of Paediatrics and Child Health (2001)
Safety, Pregnancy & Drug-Interaction Research

A case report describes increased bleeding risk when a warfarin patient also took boldo and fenugreek supplements

A patient stabilized on warfarin for atrial fibrillation showed a rise in her international normalized ratio (INR, a measure of blood clotting time) that was traced to her concurrent use of the natural products boldo and fenugreek. Her INR returned to normal within a week of stopping both products, and the abnormal INR recurred when she resumed them - a documented interaction worth knowing about for anyone combining fenugreek with anticoagulant medication, even though this specific product's own label does not carry that caution.

Case Report
Lambert & Cormier, Pharmacotherapy (2001)
Safety, Pregnancy & Drug-Interaction Research

A review of herb-drug interactions with cardiovascular medications named fenugreek among the herbs reported to increase warfarin's blood-thinning effect

This review of the medical literature from 1996 to 2003 identified 43 case reports and 8 clinical trials on interactions between herbal medicines and cardiovascular drugs. Warfarin was the cardiovascular drug most often involved, and fenugreek was named, alongside herbs like garlic, danshen and devil's claw, among those reported to increase warfarin's anticoagulant effect - the authors concluded patients on anticoagulants are at the highest risk from herb-drug interactions generally.

Review
Izzo, Di Carlo, Borrelli & Ernst, International Journal of Cardiology (2005)
Broader Context & Combination-Formula Research

A systematic review of antidiabetic plants used in Iran named fenugreek among the herbs with the best clinical-trial evidence for glycemic control

Reviewing 23 randomized controlled trials of Iranian medicinal plants for type 2 diabetes glycemic control, this systematic review found that, among all the plants studied, the strongest evidence for improving blood glucose control came from Citrullus colocynthis, Ipomoea batatas, Silybum marianum (milk thistle) and Trigonella foenum-graecum (fenugreek).

Systematic Review (23 RCTs)
Shojaii, Dabaghian, Goushegir & Fard, Acta Medica Iranica (2011)
Broader Context & Combination-Formula Research

A 12-week trial found chapatis fortified with Nigella sativa and fenugreek seed improved HbA1c, weight and fatty liver markers in diabetic and overweight adults

Forty overweight and/or type 2 diabetic subjects ate two flatbreads (chapatis) daily supplemented with a combined 5.45 g of Nigella sativa and fenugreek seed for 12 weeks, with no other lifestyle changes. By the end of the study, body weight, waist circumference, HbA1c, fasting and post-meal blood glucose, and several cholesterol markers had all significantly decreased. As a two-ingredient combination, the results reflect Nigella sativa and fenugreek together, not fenugreek in isolation.

Human Trial (n=40)
Rao, Hegde, Pacioretty, DeBenedetto & Babish, Journal of Medicinal Food (2020)
Broader Context & Combination-Formula Research

A trial found a six-herb formula containing fenugreek improved cholesterol and blood sugar control in diabetics whose dyslipidemia wasn't controlled by statins alone

Fifty type 2 diabetic patients with dyslipidemia uncontrolled by statin therapy added either a polyherbal compound (containing aloe vera, black seed, fenugreek, garlic, milk thistle and psyllium) or nothing extra to their conventional treatment for 12 weeks. The herbal-compound group showed significant improvement in triglycerides, total cholesterol, LDL cholesterol and HbA1c compared to their own baseline, with no adverse effect on kidney or liver function markers. As a six-herb combination, the benefit reflects the whole formula rather than fenugreek alone.

Human RCT (n=50)
Ghorbani, Zarvandi & Rakhshandeh, Endocrine, Metabolic & Immune Disorders Drug Targets (2019)

Customer Reviews

5.0 out of 5 · 1 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

What is Orange Naturals Fenugreek Tincture and what does it do?

It's a liquid tincture providing 250 mg of Fenugreek (seed, Trigonella foenum-graecum), 1:4 extract, per mL. Used in Herbal Medicine to support healthy glucose levels and help reduce elevated blood lipid levels, and traditionally used as a digestive tonic, appetite stimulant, mild laxative and galactogogue.

How do I take it?

Adults (19 years and older) take 4 mL, 2 times per day on an empty stomach, with 250 mL of water per dose.

Who should consult a healthcare practitioner before using it?

Consult a healthcare practitioner prior to use if you are pregnant or if you have diabetes, or if your symptoms persist or worsen.

What is Fenugreek traditionally used for?

Fenugreek seed is used in Herbal Medicine to support healthy glucose levels and help reduce elevated blood lipid levels, and traditionally used as a digestive tonic to aid digestion, to help relieve dyspepsia and gastritis, as a mild laxative, to help stimulate the appetite, as a nutritive tonic, as a galactogogue to help promote milk production, and as an expectorant to help relieve excess mucous of the upper respiratory passages.

What are the non-medicinal ingredients?

40% grain alcohol and purified water.

How much is in one bottle?

Each bottle contains 100 mL (3.38 fl oz) of tincture.

Is this a Health Canada licensed product?

Yes - it is licensed as a Natural Health Product under NPN 80031172.

Where do I buy it?

Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.

250 mg Fenugreek (seed, Trigonella foenum-graecum) per mL, 1:4 Extract100 mL (3.38 fl oz) Dropper BottleUsed in Herbal Medicine to Support Healthy Glucose Levels & Help Reduce Elevated Blood Lipid LevelsTraditionally Used in Herbal Medicine as a Digestive Tonic, Appetite Stimulant & Galactogogue

Support healthy glucose & lipid levels with Fenugreek

Get Orange Naturals Fenugreek Tincture on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80031172. Used in Herbal Medicine to support healthy glucose levels and help reduce elevated blood lipid levels. Traditionally used in Herbal Medicine as a digestive tonic to aid digestion, to help relieve dyspepsia and gastritis, as a mild laxative, to help stimulate the appetite, as a nutritive tonic, as a galactogogue to help promote milk production, and as an expectorant to help relieve excess mucous of the upper respiratory passages. Consult a healthcare practitioner prior to use if you are pregnant or have diabetes, or if symptoms persist or worsen. The research summaries on this page concern fenugreek generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a healthcare practitioner prior to use if you are pregnant. Consult a healthcare practitioner prior to use if you have diabetes. Consult a healthcare practitioner if symptoms persist. Consult a healthcare practitioner if symptoms worsen. Keep out of reach of children.

Indications

Recommended Use or Purpose: Traditionally used in Herbal Medicine to help stimulate the appetite. Traditionally used in Herbal Medicine as a digestive tonic to aid digestion. Traditionally used in Herbal Medicine to help relieve dyspepsia and gastritis. Used in Herbal Medicine as a mild laxative. Traditionally used in Herbal Medicine as an expectorant to help relieve excess mucous of the upper respiratory passages (anti-catarrhal). Traditionally used in Herbal Medicine as a nutritive tonic. Traditionally used in Herbal Medicine as a galactogogue to help promote milk production/secretion. Traditionally used in Herbal Medicine as supportive therapy for the promotion of healthy glucose levels. Used in Herbal Medicine to help reduce elevated blood lipid levels (hyperlipidemia).

Ingredients

Medicinal Ingredients (each mL contains): Fenugreek (seed, Trigonella foenum-graecum), 1:4 extract, 250 mg (0.25 g DHE). Non-medicinal Ingredients: 40% grain alcohol, purified water.

Directions

Recommended Dose (Adults 19 years and older): Take 4 mL, 2 times per day, with 250 mL of water per dose.

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