Orange Naturals Echinacea Tincture | 100mL
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 2 mL, up to 3 times per day (age-dependent) |
| Licensed Natural Health Product | NPN 80076761 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- RELIEVES SYMPTOMS OF UPPER RESPIRATORY TRACT INFECTIONS: Helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold.
- HELPS FIGHT OFF INFECTIONS: Traditionally used in Herbal Medicine to help fight off infections, especially of the upper respiratory tract.
- HELPS RELIEVE COLD SYMPTOMS: Traditionally used in Herbal Medicine to help relieve cold symptoms.
- SHORTENS THE DURATION OF COLDS: Formulated to help shorten the duration of colds and upper respiratory tract infections.
- ORGANIC ECHINACEA ROOT, 1:4 EXTRACT: Made from organic echinacea root (Echinacea purpurea), extracted at a 1:4 ratio.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80076761.
Product Description
Echinacea Tincture - Traditional Cold & Immune Support
Orange Naturals Echinacea Tincture delivers 250 mg of organic Echinacea (root, Echinacea purpurea) per mL, extracted at a 1:4 ratio in a base of grain alcohol and purified water. Helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold, and traditionally used in Herbal Medicine to help fight off infections and relieve cold symptoms. This 100 mL naturopathic tincture is licensed as a Natural Health Product. Licensed Natural Health Product NPN 80076761.
Teinture d'Échinacée d'Orange Naturals offre 250 mg d'Échinacée biologique (racine, Echinacea purpurea) par mL, extraite selon un ratio de 1:4 dans une base d'alcool de grain et d'eau purifiée. Aide à soulager les symptômes et à réduire la durée des infections des voies respiratoires supérieures, telles que le rhume, et traditionnellement utilisée en phytothérapie pour aider à combattre les infections et soulager les symptômes du rhume. Cette teinture naturopathique de 100 mL est homologuée comme produit de santé naturel. NPN 80076761.
A Traditional Root, Modern Tincture Format
250 mg Echinacea (root, Echinacea purpurea), 1:4 extract - fast-absorbing liquid format, 2 mL up to 3 times daily
250 mg Echinacea per mL
Each mL delivers a full 250 mg dose of organic Echinacea root (Echinacea purpurea), extracted at a 1:4 ratio - adults take 2 mL, 3 times per day at the first sign of infection.
Fast-Absorbing Tincture Format
As a liquid tincture, Echinacea can begin absorbing in the mouth, offering a fast-acting alternative to capsules or tablets.
Advanced Ingredients, Superior Results
Echinacea purpurea is one of the most widely studied roots in herbal medicine for cold and respiratory support, explored for its role in direct antiviral activity, immune gene modulation and reducing the duration and severity of upper respiratory tract infections. Here is what the wider research explores.
Echinacea (root, Echinacea purpurea)
A widely studied cold-season root, explored for direct antiviral/virucidal activity, immune gene modulation and reducing the duration and severity of upper respiratory tract infections.
250 mg per mL, 1:4 extract
Orange Naturals Echinacea Tincture: Supplement Facts
Each mL contains:
- Echinacea (root, Echinacea purpurea), 1:4 extract250 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: 40% grain alcohol, purified water.
Recommended Use or Purpose: Helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold. Traditionally used in Herbal Medicine to help relieve cold symptoms and symptoms of upper respiratory tract infections. Used in Herbal Medicine to help fight off infections, especially of the upper respiratory tract.
Recommended Dose: Children 5 to 14 years: Take 2 mL, 1 time per day. Adults and adolescents 15 years and older: Take 2 mL, 3 times per day. Take at the first sign of infection, on an empty stomach. Consult a healthcare practitioner for use beyond 2 months.
Cautions and Warnings: Consult a healthcare practitioner if symptoms persist or worsen. Consult a healthcare practitioner before use if you have a progressive systemic disease such as tuberculosis, collagenosis, multiple sclerosis, or an immune system disorder. Consult a healthcare practitioner before use if you are taking medications that suppress the immune system. Stop use if hypersensitivity/allergy occurs. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque mL contient :
- Échinacée (racine, Echinacea purpurea), extrait 1:4250 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Alcool de grain à 40 %, eau purifiée.
Usage ou fins recommandés : Aide à soulager les symptômes et à réduire la durée des infections des voies respiratoires supérieures, telles que le rhume. Utilisé traditionnellement en phytothérapie pour aider à soulager les symptômes du rhume et les symptômes des infections des voies respiratoires supérieures. Utilisé en phytothérapie pour aider à combattre les infections, particulièrement les infections des voies respiratoires supérieures.
Posologie recommandée : Enfants de 5 à 14 ans : Prendre 2 mL, 1 fois par jour. Adultes et adolescents de 15 ans et plus : Prendre 2 mL, 3 fois par jour. Prendre dès les premiers signes d'une infection, à jeun. Consulter un praticien de santé pour un usage de plus de 2 mois.
Mises en garde : Consultez un praticien de soins de santé si les symptômes persistent ou s'aggravent. Consultez un praticien de soins de santé avant l'utilisation si vous avez une maladie systémique progressive telle que la tuberculose, la collagénose, la sclérose en plaques, ou une maladie du système immunitaire. Consultez un praticien de soins de santé avant l'utilisation si vous prenez des médicaments qui inhibent le système immunitaire. Cessez d'utiliser si une hypersensibilité/allergie se manifeste. Garder hors de la portée des enfants.
NPN 80076761
Fight off colds and infections with Echinacea
Get Orange Naturals Echinacea Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Echinacea Tincture
250 mg of Echinacea (root, Echinacea purpurea) per mL, 1:4 extract - a traditional cold-season root in a fast-absorbing tincture format.
250 mg Echinacea per mL
Each mL delivers a full 250 mg dose of organic Echinacea root (Echinacea purpurea), extracted at a 1:4 ratio.
Helps relieve & shorten colds
Helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold.
Fast-absorbing liquid tincture
Take at the first sign of infection - a fast-acting alternative to capsules.
Made in Canada, Health Canada licensed
Formulated by Orange Naturals and licensed as a Natural Health Product. NPN 80076761.
Inside every mL
250 mg Echinacea (root, Echinacea purpurea), 1:4 extract, per mL - ages 5-14: 2 mL, 1 time per day; ages 15 and over: 2 mL, 3 times per day. Take at the first sign of infection, on an empty stomach. Non-medicinal ingredients: 40% grain alcohol and purified water.
How to use it
Take at the first sign of infection
Ages 5-14: take 2 mL, 1 time per day. Ages 15 and over: take 2 mL, 3 times per day. Take on an empty stomach.
Use the dropper for accurate dosing
Each 100 mL bottle is designed for precise, drop-by-drop dosing directly into the mouth or in a small amount of water.
Consult a practitioner for extended use or certain conditions
Consult a healthcare practitioner for use beyond 2 months, or before use if you have a progressive systemic disease (such as tuberculosis, collagenosis or multiple sclerosis) or an immune system disorder, or if you are taking medications that suppress the immune system.
What the research says about Echinacea
Educational summaries of published research on Echinacea purpurea generally; not product-specific claims. Orange Naturals Echinacea Tincture's own authorized use under NPN 80076761 is that it helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold.
A large NIH-funded trial found a modest, non-significant trend toward benefit from Echinacea for treating the common cold
In 719 adults and adolescents with a new cold, randomized to no pills, blinded placebo, blinded Echinacea, or open-label Echinacea, illness severity and duration were slightly lower in the Echinacea groups than placebo, but the difference did not reach statistical significance. The authors concluded this dose and formulation did not substantively change the course of the common cold, while noting higher-than-expected variability limited their power to detect small benefits.
Human RCT (n=719)A 128-patient trial found no significant difference between Echinacea purpurea and placebo for cold symptoms or duration
Patients with a new cold took either 100 mg of Echinacea purpurea (freeze-dried pressed juice) or a placebo three times daily until symptoms resolved. Total and individual symptom scores, and the time to symptom resolution, did not differ significantly between groups. The authors called for further studies with different preparations and doses to validate earlier positive claims.
Human RCT (n=128)A standardized fresh-plant Echinacea formulation reduced cold symptom severity by 23% compared to placebo
Adults with a history of frequent colds took a highly standardized Echinacea purpurea formulation (Echinilin, containing defined levels of alkamides, cichoric acid and polysaccharides) or placebo starting at the first sign of a cold. Among those who followed the full protocol, total daily symptom scores were 23.1% lower in the Echinacea group, with a greater response rate throughout treatment and a similar adverse-event profile to placebo.
Human RCT (n=128 with colds)A Cochrane review of 24 trials found no single prevention trial significant, but pooled results suggested a modest benefit
Reviewing 24 double-blind trials of 4,631 participants comparing Echinacea preparations to placebo, none of the 12 individual cold-prevention comparisons reached statistical significance, though a post-hoc pooling suggested a 10-20% relative risk reduction. Only 1 of 7 treatment trials reporting cold duration showed a significant effect, and adverse-event dropout rates did not differ significantly between groups.
Meta-analysis (Cochrane)A meta-analysis of 14 studies found Echinacea reduced the odds of catching a cold by 58% and shortened its duration by 1.4 days
Pooling 14 studies on Echinacea and the common cold, the odds of developing a cold were 58% lower with Echinacea than placebo, and cold duration was shortened by a weighted average of 1.4 days. Significant reductions held up across several subgroup analyses, including different Echinacea products and study-quality thresholds.
Meta-analysisA meta-analysis of experimentally induced rhinovirus colds found Echinacea reduced the likelihood of developing a clinical cold
Pooling three studies that deliberately exposed volunteers to rhinovirus under controlled conditions, the likelihood of developing a symptomatic cold was 55% higher with placebo than with Echinacea. The authors noted this experimental-infection design controls for some of the variability that complicates studies of naturally occurring colds, and called for further appropriately powered trials.
Meta-analysis (induced-infection studies)A standardized Echinacea purpurea preparation directly inactivated multiple coronaviruses, including SARS-CoV-2, on contact
Echinaforce, a standardized Echinacea purpurea preparation, irreversibly inactivated the common-cold coronavirus HCoV-229E upon direct contact in the laboratory. The same virucidal activity extended to the more severe MERS-CoV, SARS-CoV-1 and SARS-CoV-2 at comparable concentrations, and the extract also showed a protective effect in a reconstituted human nasal-epithelium tissue model mimicking natural infection.
In vitro studyLaboratory screening found Echinacea extracts showed antiviral and virucidal activity against SARS-CoV-2
Testing root, seed and aerial-part extracts of Echinacea purpurea and Echinacea angustifolia against SARS-CoV-2 in lab-grown cells, the extracts reduced viral load through the infectious cycle, with molecular modeling identifying specific compounds (including echinacoside and several flavonoids) as likely contributors to the antiviral effect, alongside a companion extract tested in the same study.
In vitro studyA specific Echinacea alkylamide showed potent antiviral activity against rhinovirus and influenza virus in the lab
Testing individual alkylamides isolated from Echinacea root extract, researchers found that one compound, dodeca-2,4-dienoic acid isobutylamide, had potent antiviral activity against both rhinovirus (the leading cause of the common cold) and influenza virus, while also strongly inhibiting IL-8, a cytokine responsible for many cold symptoms, with low toxicity to cells.
In vitro studyGene array analysis found Echinacea extracts activated immune-response genes and blunted some rhinovirus effects in respiratory cells
Testing two Echinacea extracts on human bronchial epithelial cells with and without rhinovirus infection across more than 13,000 genes, both extracts stimulated numerous cytokine and chemokine genes, with the effects converging on the transcription factor C/EBP-beta as a central node, and tended to neutralize some of the changes rhinovirus infection caused on its own.
Preclinical study (human cell line)Root and leaf extracts of Echinacea purpurea had opposite effects on human dendritic cell maturation markers
Comparing extracts from the root versus the stem-and-leaf tissue of Echinacea purpurea on human dendritic cells (key antigen-presenting immune cells), the two extracts produced opposite effects on the CD83 maturation marker and on specific chemokine genes, showing that different plant parts of the same species can modulate immune-cell gene expression in different directions.
Preclinical study (human cell line)Echinacea alkylamides were shown to activate a cannabinoid receptor pathway that regulates TNF-alpha production
Testing a standardized Echinacea tincture on human immune cells, researchers found it induced TNF-alpha gene activity in macrophages while modulating an already-triggered inflammatory response in a two-phase pattern. The effect was traced to specific alkylamides acting through the CB2 cannabinoid receptor and several downstream signaling pathways, offering one of the first proposed molecular mechanisms for Echinacea's immune effects.
Preclinical study (human cell line)A review found Echinacea's alkamides reach the bloodstream after oral dosing and bind cannabinoid receptors
Reviewing the pharmacology of Echinacea's alkamides, the major lipophilic constituents of Echinacea preparations, the review found these compounds are detectable in human blood at meaningful concentrations after oral dosing and bind significantly to CB2 cannabinoid receptors, proposing this as Echinacea's likely mode of action as an immunomodulator, while noting minimal risk of interaction with medications metabolized by P450 liver enzymes with prolonged use.
ReviewA review named Echinacea's alkamides among the best-known plant-derived cannabinoid-receptor ligands
Surveying plant-derived compounds that bind cannabinoid receptors, the review identified Cannabis sativa's THC and Echinacea's lipophilic alkamides as the two best-studied examples of plant cannabimimetics, discussing their potential therapeutic and immunomodulatory effects through cannabinoid-receptor signaling.
ReviewA comprehensive review catalogued the chemistry and quality variability across the three medicinal Echinacea species
Reviewing the chemistry, pharmacology and clinical properties of Echinacea angustifolia, Echinacea pallida and Echinacea purpurea, the review identified alkamides and caffeic-acid derivatives as key active-constituent classes, while noting that commercial Echinacea products can vary in species and plant part used, and that analysis of marketed products has found some do not meet recognized quality standards.
ReviewA meta-analysis of 9 pediatric trials found Echinacea purpurea reduced respiratory infection duration, incidence and antibiotic use in children
Pooling 9 randomized trials with over 3,000 children, Echinacea purpurea significantly reduced the duration and incidence of upper respiratory tract infections and antibiotic use, and lowered the incidence of ear-infection episodes (though not their duration). Adverse events were moderately more common with Echinacea than placebo, though generally mild.
Meta-analysis (pediatric, n=3169)A systematic review found high-certainty evidence that Echinacea reduces symptom duration and antibiotic use in children with acute respiratory infections
Reviewing randomized trials of Echinacea for acute cough and respiratory tract infections in children, the review found high-certainty evidence for reduced symptom duration and antibiotic use, and moderate-certainty evidence for infection prevention, with higher-dose Echinacea purpurea formulations showing more consistent benefit. Echinacea was generally well tolerated, with only mild gastrointestinal discomfort and skin rashes reported.
Systematic Review (pediatric)A pharmacovigilance study found Echinacea purpurea among the herbs most frequently linked to allergy-like reactions in children
Reviewing nearly 50 years of allergy-like adverse-reaction reports for herbal medicines in children from the WHO's global VigiBase safety database, Echinacea purpurea was the third most frequently implicated single herb (5.6% of qualifying cases), behind only mixed herbal products and ivy (Hedera helix), with urticaria/rash and allergic reaction the most common reported symptoms - an honest safety signal worth noting alongside Echinacea's efficacy data.
Pharmacovigilance study (pediatric, 1968-2014)A 409-adult trial of higher-dose Echinacea formulations found good, similar tolerability to conventional lower-dose formulations
Adults with an acute respiratory infection were randomized to one of four Echinacea formulations at either higher therapeutic or conventional preventive doses. Tolerability and safety were good and similar between the higher- and lower-dose groups (adverse events 12% vs 6%), though one severe adverse event with a possible hypersensitivity reaction occurred in a recipient of the novel higher-dose spray formulation - reported here as an honest part of the safety picture.
Human RCT (n=409)A pharmacokinetic study found short-term Echinacea use altered the activity of two liver drug-metabolizing enzymes
Twelve healthy adults took 400 mg of Echinacea purpurea root four times daily for 8 days alongside marker drugs for several cytochrome P450 liver enzymes. Echinacea reduced the clearance of a CYP1A2-metabolized drug (caffeine) and selectively altered CYP3A activity at the liver and intestine, but did not significantly affect CYP2C9 or CYP2D6 - a real, nuanced interaction caution for anyone combining Echinacea with medications cleared by those specific pathways.
Human study (n=12)A physician review concluded Echinacea treatment (not prevention) shows a modest real benefit with an uncommon, minor side-effect profile
Reviewing the Echinacea literature for family physicians, the review concluded that prophylactic Echinacea does not meaningfully reduce the frequency, severity or duration of upper respiratory infections, while treatment-focused use appears to offer a modest positive effect. No significant herb-drug interactions were reported, and adverse effects were generally uncommon and minor, such as abdominal upset, nausea and dizziness.
ReviewA review traced Echinacea's use from traditional wound care and immune support to modern antioxidant and antibacterial research
Surveying Echinacea's cultivation, traditional uses and modern research, the review described a long history of use for wound healing, immune support and respiratory symptoms caused by bacterial infection, alongside modern evidence of antioxidant and antimicrobial activity, and characterized Echinacea extracts as generally safe across the literature surveyed.
ReviewA physician review of complementary approaches to the common cold found Echinacea purpurea effective in 5 of 6 treatment trials reviewed
Reviewing complementary and alternative approaches to preventing and treating the common cold for Canadian family physicians, the review found moderate evidence supporting Echinacea purpurea specifically for treatment (effective in 5 of 6 trials reviewed), naming it among the more consistently useful natural options studied, alongside vitamin C for prevention and zinc lozenges for treatment.
ReviewA JAMA evidence synopsis found no significant prevention effect but a small exploratory benefit on cold incidence
Distilling the Cochrane systematic review of Echinacea for the common cold for a clinical audience, this evidence synopsis reported that individual prophylaxis trials showed no association between Echinacea and cold prevention, though exploratory pooled analysis suggested a small reduction in cold incidence; treatment trials showed no association with a shorter cold duration - an honest, balanced closing summary of a genuinely mixed evidence base.
Evidence synopsisFrequently asked questions
What is Orange Naturals Echinacea Tincture and what does it do?
It's a liquid tincture providing 250 mg of Echinacea (root, Echinacea purpurea), 1:4 extract, per mL. It helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold.
How do I take it?
Ages 5 to 14: take 2 mL, 1 time per day. Ages 15 and over: take 2 mL, 3 times per day. Take on an empty stomach at the first sign of infection.
How long can I take it for?
Consult a healthcare practitioner for use beyond 2 months.
Who should consult a healthcare practitioner before using it?
Anyone with a progressive systemic disease such as tuberculosis, collagenosis or multiple sclerosis, anyone with an immune system disorder, or anyone taking medications that suppress the immune system.
Who should stop using it?
Stop use and consult a healthcare practitioner if a hypersensitivity or allergic reaction occurs, or if symptoms persist or worsen.
What are the non-medicinal ingredients?
40% grain alcohol and purified water.
How much is in one bottle?
Each bottle contains 100 mL (3.38 fl oz) of tincture.
Is this a Health Canada licensed product?
Yes - it is licensed as a Natural Health Product under NPN 80076761.
Fight off colds and infections with Echinacea
Get Orange Naturals Echinacea Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80076761. Helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold. Consult a healthcare practitioner before use if you have a progressive systemic disease or are taking medications that suppress the immune system. The research summaries on this page concern Echinacea purpurea generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner if symptoms persist or worsen. Consult a healthcare practitioner before use if you have a progressive systemic disease such as tuberculosis, collagenosis, multiple sclerosis, or an immune system disorder. Consult a healthcare practitioner before use if you are taking medications that suppress the immune system. Stop use if hypersensitivity/allergy occurs. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps to relieve the symptoms and shorten the duration of upper respiratory tract infections, such as the common cold. Traditionally used in Herbal Medicine to help relieve cold symptoms and symptoms of upper respiratory tract infections. Used in Herbal Medicine to help fight off infections, especially of the upper respiratory tract.
Ingredients
Medicinal Ingredients (each mL contains): Echinacea (root, Echinacea purpurea), 1:4 extract, 250 mg (0.25 g DHE). Non-medicinal Ingredients: 40% grain alcohol, purified water.
Directions
Recommended Dose: Children 5 to 14 years: Take 2 mL, 1 time per day. Adults and adolescents 15 years and older: Take 2 mL, 3 times per day. Take at the first sign of infection, on an empty stomach. Consult a healthcare practitioner for use beyond 2 months.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.