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Health Canada NPN 80036529 7 Digestive Herbs: Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian & Peppermint Made in Canada · Naturopathic Tincture Traditionally Used in Herbal Medicine to Aid Digestion
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Orange Naturals Digestion Tincture | 100mL

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$23.96 CAD ($0.24 / mL)
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BrandOrange
Serving2 mL, 3 times per day
Licensed Natural Health ProductNPN 80036529
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • AIDS DIGESTION: Traditionally used in Herbal Medicine as a digestive tonic and bitter to help stimulate appetite and aid digestion.
  • HELPS RELIEVE DIGESTIVE DISTURBANCES: Traditionally used in Herbal Medicine to help relieve digestive disturbances and dyspepsia, including flatulent dyspepsia (gas and bloating).
  • HELPS PREVENT NAUSEA: Traditionally used in Herbal Medicine to help prevent nausea.
  • HELPS INCREASE BILE FLOW: Used in Herbal Medicine to help increase bile flow (cholagogue).
  • 7-HERB NATUROPATHIC BLEND: Combines Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint in a fast-absorbing liquid tincture.
  • MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80036529.

Customer Reviews

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Product Description

Digestion Tincture - 7-Herb Naturopathic Digestive Bitters

Orange Naturals Digestion Tincture

Orange Naturals Digestion Tincture combines seven traditional digestive herbs - Angelica (50 mg), Artichoke (50 mg), Licorice (40 mg), Chamomile (25 mg), Dandelion (25 mg), Gentian (25 mg) and Peppermint (25 mg) per mL - in a fast-absorbing naturopathic tincture. Traditionally used in Herbal Medicine to help relieve digestive disturbances and flatulent dyspepsia, as a digestive tonic and bitter to help stimulate appetite and aid digestion, to help prevent nausea, and to help increase bile flow. This 100 mL tincture is licensed as a Natural Health Product. Licensed Natural Health Product NPN 80036529.

La teinture Digestion d'Orange Naturals combine sept plantes digestives traditionnelles - Angélique (50 mg), Artichaut (50 mg), Réglisse (40 mg), Camomille (25 mg), Pissenlit (25 mg), Gentiane (25 mg) et Menthe poivrée (25 mg) par mL - dans une teinture naturopathique à absorption rapide. Utilisée traditionnellement en phytothérapie pour aider à soulager les troubles digestifs et la dyspepsie flatulente, comme tonique digestif et amer pour aider à stimuler l'appétit et la digestion, pour aider à prévenir les nausées, et pour aider à augmenter l'écoulement de la bile. Cette teinture naturopathique de 100 mL est homologuée comme produit de santé naturel. NPN 80036529.

Digestion Tincture lifestyle
Orange Naturals Digestion Tincture
7 Digestive Herbs · Angelica, Artichoke & Gentian Bitters Blend

7 Traditional Bitters, One Fast-Absorbing Tincture

Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint - fast-absorbing liquid format, 2 mL 3 times daily before meals

7-Herb Digestive Bitters Blend

Each mL delivers Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint - traditional bitter and aromatic herbs combined to help aid digestion.

Fast-Absorbing Tincture Format

As a liquid tincture, this 7-herb blend can begin absorbing under the tongue, offering a fast-acting alternative to capsules or tablets before meals.

Advanced Ingredients, Superior Results

Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint are each long-studied individually - and in combination with other bitter herbs - for their roles in digestion, gastric comfort and gut health. Here is what the wider research explores about each.

Angelica (root, Angelica archangelica)

A traditional aromatic root long used as a digestive tonic and carminative to help settle the stomach.

50 mg per mL, 1:4 extract

Artichoke (leaf, Cynara cardunculus)

A bitter leaf studied for its role in bile flow, dyspepsia relief and digestive comfort.

50 mg per mL, 1:4 extract

Licorice (root and stolon, Glycyrrhiza glabra)

A soothing root traditionally used to help calm digestive irritation.

40 mg per mL, 1:5 extract

Chamomile (flower, Matricaria chamomilla)

A gentle flower traditionally used to calm the digestive tract and ease occasional stomach upset.

25 mg per mL, 1:4 extract

Dandelion (root, Taraxacum officinale)

A traditional bitter root used to help increase bile flow and support digestion.

25 mg per mL, 1:4 extract

Gentian (root, Gentiana lutea)

One of the most bitter roots in traditional herbal medicine, used to stimulate the appetite and digestive juices.

25 mg per mL, 1:4 extract

Peppermint (leaf, Mentha x piperita)

A cooling, aromatic leaf traditionally used to help relieve gas and digestive discomfort.

25 mg per mL, 1:4 extract

Orange Naturals Digestion Tincture: Supplement Facts

Orange™Digestion Tincture
English

Each mL contains:

  • Angelica (root, Angelica archangelica), 1:4 extract50 mg
  • Artichoke (leaf, Cynara cardunculus), 1:4 extract50 mg
  • Licorice (root and stolon, Glycyrrhiza glabra), 1:5 extract40 mg
  • Chamomile (flower, Matricaria chamomilla), 1:4 extract25 mg
  • Dandelion (root, Taraxacum officinale), 1:4 extract25 mg
  • Gentian (root, Gentiana lutea), 1:4 extract25 mg
  • Peppermint (leaf, Mentha x piperita), 1:4 extract25 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: 40% grain alcohol, purified water.

Recommended Use or Purpose: Traditionally used in Herbal Medicine to help relieve digestive disturbances/dyspepsia. Traditionally used in Herbal Medicine to help relieve flatulent dyspepsia (carminative). Traditionally used in Herbal Medicine as a digestive tonic and bitter to help stimulate appetite and aid digestion (stomachic). Traditionally used in Herbal Medicine to help prevent nausea (anti-emetic). Used in Herbal Medicine to help increase bile flow (cholagogue).

Recommended Dose (Adults): Take 2 mL, 3 times per day under the tongue or in a little water, on an empty stomach (15 to 60 minutes before meals). Recommended Duration of Use: Consult a healthcare practitioner for use beyond 1 month.

Cautions and Warnings: Do not use if you are pregnant or breastfeeding, or if you are allergic to plants of the Asteraceae/Compositae/Daisy family. Do not use if you have a bile duct or bowel obstruction, acute stomach irritation or inflammation, stomach or duodenal ulcers, hypokalemia, high blood pressure, or a cardiovascular, kidney or liver disorder. Do not use if you are taking thiazide diuretics, cardiac glycosides, corticosteroids, stimulant laxatives, or other medications that may aggravate electrolyte imbalance. Consult a healthcare practitioner prior to use if you have gallstones, a peptic ulcer, a liver disorder or anemia, or if symptoms persist or worsen. Avoid prolonged exposure to sunlight, ultraviolet light (UV) or UV therapy. Discontinue use if you develop symptoms of liver trouble or hypersensitivity. May cause headaches. Stop use and seek medical attention immediately if you experience dizziness, confusion, muscle weakness or pain, an abnormal heartbeat, or difficulty breathing. Do not use if the seal is broken. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

Français

Chaque mL contient :

  • Angélique (racine, Angelica archangelica), extrait 1:450 mg
  • Artichaut (feuille, Cynara cardunculus), extrait 1:450 mg
  • Réglisse (racine et stolon, Glycyrrhiza glabra), extrait 1:540 mg
  • Camomille (fleur, Matricaria chamomilla), extrait 1:425 mg
  • Pissenlit (racine, Taraxacum officinale), extrait 1:425 mg
  • Gentiane (racine, Gentiana lutea), extrait 1:425 mg
  • Menthe poivrée (feuille, Mentha x piperita), extrait 1:425 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Alcool de grain à 40 %, eau purifiée.

Usage ou fins recommandés : Utilisé traditionnellement en phytothérapie pour aider à soulager les troubles digestifs et la dyspepsie. Utilisé traditionnellement en phytothérapie pour aider à soulager la dyspepsie flatulente (carminatif). Utilisé traditionnellement en phytothérapie comme tonique digestif et amer pour aider à stimuler l'appétit et la digestion (stomachique). Utilisé traditionnellement en phytothérapie pour aider à prévenir les nausées (antiémétique). Utilisé en phytothérapie pour aider à augmenter l'écoulement de la bile (cholagogue).

Posologie recommandée (adultes) : Prendre 2 ml, sous la langue ou dans un peu d'eau, à jeun, 3 fois par jour (15 à 60 minutes avant les repas). Consulter un praticien de soins de santé pour un usage de plus d'un mois.

Mises en garde : Ne pas utiliser si vous êtes enceinte ou allaitez, ou si vous êtes allergique aux plantes de la famille des Astéracées/Composées/marguerites. Ne pas utiliser si vous souffrez d'une obstruction des voies biliaires ou intestinale, d'une irritation aiguë de l'estomac, d'ulcères gastriques ou duodénaux, d'hypokaliémie, d'hypertension, ou d'un trouble cardiovasculaire, rénal ou hépatique. Ne pas utiliser si vous prenez des diurétiques thiazidiques, des glucosides cardiotoniques, des corticostéroïdes, des laxatifs stimulants, ou tout autre médicament pouvant aggraver le déséquilibre des électrolytes. Consulter un praticien de la santé avant l'usage si vous souffrez de calculs biliaires, d'un ulcère peptique, d'un trouble hépatique ou d'anémie, ou si les symptômes persistent ou s'aggravent. Éviter une exposition prolongée à la lumière du soleil, aux rayons ultraviolets (UV) ou à la luminothérapie UV. Cesser l'utilisation si des symptômes de troubles hépatiques ou d'hypersensibilité se manifestent. Peut causer des maux de tête. Cesser l'utilisation et consulter immédiatement un médecin en cas d'étourdissements, de confusion, de faiblesse ou de douleur musculaire, de battements cardiaques anormaux, ou de difficulté à respirer. Ne pas utiliser si le sceau est brisé. Garder hors de la portée des enfants.

NPN 80036529

7-Herb Digestive Bitters: Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian & Peppermint100 mL (3.38 fl oz) Dropper BottleTraditionally Used in Herbal Medicine to Aid Digestion and Relieve Digestive DisturbancesHelps Increase Bile Flow and Helps Prevent Nausea

Support digestion with a 7-herb bitters tincture

Get Orange Naturals Digestion Tincture on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why Orange Naturals Digestion Tincture

Seven traditional digestive herbs in one fast-absorbing tincture - Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint.

7 Real Digestive Herbs

Each mL delivers a full 7-herb blend - Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint.

Helps relieve digestive disturbances

Traditionally used in Herbal Medicine to help relieve digestive disturbances, dyspepsia and flatulent dyspepsia.

Fast-absorbing liquid tincture

Take 2 mL, 3 times per day under the tongue or in a little water, on an empty stomach before meals.

Made in Canada, Health Canada licensed

Formulated by Orange Naturals and licensed as a Natural Health Product. NPN 80036529.

Inside every mL

Angelica 50 mg, Artichoke 50 mg, Licorice 40 mg, Chamomile 25 mg, Dandelion 25 mg, Gentian 25 mg and Peppermint 25 mg - take 2 mL, 3 times per day under the tongue or in a little water, on an empty stomach. Non-medicinal ingredients: 40% grain alcohol and purified water.

Angelica (root, Angelica archangelica) 50 mg per mL, 1:4 extractArtichoke (leaf, Cynara cardunculus) 50 mg per mL, 1:4 extractLicorice (root and stolon, Glycyrrhiza glabra) 40 mg per mL, 1:5 extractChamomile (flower, Matricaria chamomilla) 25 mg per mL, 1:4 extractDandelion (root, Taraxacum officinale) 25 mg per mL, 1:4 extractGentian (root, Gentiana lutea) 25 mg per mL, 1:4 extractPeppermint (leaf, Mentha x piperita) 25 mg per mL, 1:4 extract

How to use it

Take 2 mL, 3 times daily before meals

Adults: take 2 mL, 3 times per day under the tongue or in a little water, on an empty stomach (15 to 60 minutes before meals).

Use the dropper for accurate dosing

Each 100 mL bottle is designed for precise, drop-by-drop dosing directly under the tongue or in a small amount of water.

Consult a practitioner for use beyond 1 month

Consult a healthcare practitioner for use beyond 1 month, or if you have certain digestive, liver, kidney or cardiovascular conditions - see full cautions.

What the research says about these ingredients

Educational summaries of published research on Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint generally; not product-specific claims. Orange Naturals Digestion Tincture's own authorized use under NPN 80036529 is that it is traditionally used in Herbal Medicine to help relieve digestive disturbances and flatulent dyspepsia, as a digestive tonic and bitter to help stimulate appetite and aid digestion, to help prevent nausea, and to help increase bile flow.

Artichoke (Cynara cardunculus) - Dyspepsia Trials

A multicentre randomized trial found artichoke leaf extract significantly improved functional dyspepsia symptoms and quality of life

In a six-week, placebo-controlled, double-blind trial of 244 patients with functional dyspepsia, artichoke leaf extract produced significantly greater improvement in dyspeptic symptoms than placebo, and patients on the extract also showed significantly greater improvement in disease-specific quality of life scores.

Human RCT (n=244)
Holtmann et al., Alimentary Pharmacology & Therapeutics (2003)
Artichoke (Cynara cardunculus) - Dyspepsia Trials

A subset analysis found artichoke leaf extract reduced irritable bowel syndrome symptoms in volunteers with concomitant dyspepsia

Among 208 adults with dyspepsia who were also identified as having irritable bowel syndrome, a two-month course of artichoke leaf extract was followed by a significant 26.4% fall in IBS incidence, a shift in bowel pattern toward normal, and a 41% reduction in total dyspepsia symptom scores.

Human study (n=208)
Bundy, Walker, Middleton, Marakis & Booth, Journal of Alternative and Complementary Medicine (2004)
Artichoke (Cynara cardunculus) - Dyspepsia Trials

A randomized trial found a ginger and artichoke leaf extract combination significantly eased functional dyspepsia symptoms

In 126 patients with functional dyspepsia given a ginger and artichoke leaf extract supplement or placebo for four weeks, the supplement group showed significantly greater improvement than placebo, with particular benefit for nausea, epigastric fullness, epigastric pain and bloating.

Human RCT (n=126)
Giacosa et al., Evidence-Based Complementary and Alternative Medicine (2015)
Gentian (Gentiana) - Bitter Tonic Phytochemistry

A study measuring bitterness values found traditional African tonic plants rivalled internationally known bitters used to stimulate digestion

Researchers measured the bitterness values of 15 southern African plants traditionally used as digestive tonics and found most were very bitter, with values comparable to internationally recognized bitter tonics such as Gentiana lutea (gentian) - supporting the idea that a bitter-tasting stimulation of the vagus nerve and gastric juices underlies the traditional use of bitter herbs to aid digestion and appetite.

Phytochemical study
Olivier & van Wyk, Journal of Ethnopharmacology (2013)
Gentian (Gentiana) - Bitter Tonic Phytochemistry

A systematic review of a related Gentiana root used in traditional medicine found bile-promoting and liver-protective pharmacological activities

Reviewing Gentianae Macrophyllae Radix (Qin-Jiao), a root from a related Gentiana species used in traditional Chinese herbal medicine, researchers catalogued antiviral, liver-protective, bile-promoting and immune-regulating pharmacological activities linked to its iridoid, triterpenoid and flavonoid compounds.

Systematic review
Cui et al., Journal of Ethnopharmacology (2025)
Gentian (Gentiana) - Bitter Tonic Phytochemistry

A review of the genus Gentiana catalogued the bitter iridoid and xanthone compounds behind its traditional digestive reputation

This review of Gentiana species phytochemistry identified iridoids, xanthones, flavonoids, triterpenoids and alkaloids as the genus's principal bioactive compound classes, and summarized pharmacological activities including anti-inflammatory and hepatoprotective effects reported across various Gentiana species.

Review
Pan, Zhao, Zhang, Li & Wang, Chemistry & Biodiversity (2016)
Peppermint (Mentha piperita) - IBS & Functional Dyspepsia

A review found peppermint oil affects gastrointestinal physiology and is supported by placebo-controlled trials in IBS and functional dyspepsia

Reviewing peppermint oil's effects throughout the gastrointestinal tract, researchers described mechanisms including smooth muscle relaxation and visceral sensitivity modulation, and concluded that placebo-controlled studies support its use in irritable bowel syndrome, functional dyspepsia and childhood functional abdominal pain, with a good overall safety profile.

Review
Chumpitazi, Kearns & Shulman, Alimentary Pharmacology & Therapeutics (2018)
Peppermint (Mentha piperita) - IBS & Functional Dyspepsia

A meta-analysis found a peppermint oil and caraway oil combination significantly reduced pain in functional dyspepsia

Pooling three randomized trials with 249 functional dyspepsia patients, a proprietary peppermint oil and caraway oil combination (Menthacarin, not this product's own formula) produced a significant reduction in pain intensity and overall symptom improvement compared with placebo, with additional favorable results reported across 580 patients in five trials overall.

Meta-analysis
Madisch et al., Digestive Diseases (2022)
Peppermint (Mentha piperita) - IBS & Functional Dyspepsia

A systematic review of treatments for recurrent childhood abdominal pain found peppermint oil capsules reduced pain outcomes

Reviewing 10 randomized controlled trials of treatments for recurrent abdominal pain in children aged 5 to 18, the authors found that enteric-coated peppermint oil capsules, among other therapies, were associated with a decrease in measured pain outcomes compared with control groups.

Systematic review
Weydert, Ball & Davis, Pediatrics (2003)
Chamomile (Matricaria chamomilla) - Traditional Use, Safety & Anti-Inflammatory Mechanism

A systematic review of 72 clinical trials found chamomile generally safe with only mild, self-limiting adverse events

Reviewing adverse events reported across 72 clinical trials totalling 2,896 chamomile-treated patients, researchers found the most common adverse events were mild gastrointestinal complaints and drowsiness, both self-limiting; allergic reactions were rare and mainly reported in individual case reports rather than controlled trials.

Systematic review
Ostovar, Rezaee, Najibi & Hashempur, Complementary Therapies in Medicine (2025)
Chamomile (Matricaria chamomilla) - Traditional Use, Safety & Anti-Inflammatory Mechanism

A review catalogued chamomile's traditional digestive and antiemetic uses alongside its phytochemistry

This review of chamomile's ethnomedicinal use, phytochemistry and pharmacology described its long traditional use for gastrointestinal, respiratory and liver disorders, including as a sedative, antispasmodic and antiemetic, and linked these uses to bioactive compounds such as alpha-bisabolol, chamazulene and various flavonoids identified in the plant's essential oil and extracts.

Review
El Mihyaoui et al., Life (2022)
Chamomile (Matricaria chamomilla) - Traditional Use, Safety & Anti-Inflammatory Mechanism

A laboratory study found chamomile essential oils suppressed inflammatory signaling in human and mouse immune cells

Testing chamomile essential oils on human peripheral blood cells and mouse macrophages exposed to an inflammatory trigger, researchers found the oils significantly reduced nitric oxide, TNF-alpha and IL-6 production by suppressing activation of NF-kB, a master inflammatory signaling switch, while also boosting the cells' own antioxidant enzyme defenses.

Preclinical study (human/mouse cells)
De Cicco et al., Journal of Ethnopharmacology (2023)
Licorice (Glycyrrhiza glabra) - Gastric Mucosal Protection

A study found deglycyrrhizinated licorice reduced aspirin-induced gastric mucosal damage in rats

In rats given aspirin alone or combined with a bile acid known to worsen gastric injury, deglycyrrhizinated licorice (DGL) significantly reduced gastric lesion scores in both conditions, with evidence of both a local protective effect on the stomach lining and a systemic effect when given by injection.

Preclinical study (rat)
Russell, Morgan & Nelson, Scandinavian Journal of Gastroenterology Supplement (1984)
Licorice (Glycyrrhiza glabra) - Gastric Mucosal Protection

A study found combining deglycyrrhizinated licorice with a low dose of an acid-reducing drug gave greater gastric protection than either alone

In rats given aspirin to induce gastric mucosal damage, a combination of low-dose cimetidine (an acid-reducing drug) and deglycyrrhizinated licorice provided significantly greater protection against gastric injury than either agent given alone at the same low dose.

Preclinical study (rat)
Bennett, Clark-Wibberley, Stamford & Wright, Journal of Pharmacy and Pharmacology (1980)
Licorice (Glycyrrhiza glabra) - Gastric Mucosal Protection

A study found a licorice flavonoid reduced ethanol-induced gastric ulcers in rats by suppressing cell death signaling

In rats with ethanol-induced gastric ulcers, treatment with a licorice-derived flavonoid reduced ulcer severity and regulated genes linked to gastric injury; network and molecular analysis identified the PI3K/AKT signaling pathway as a key mechanism through which the flavonoid reduced programmed cell death in the stomach lining.

Preclinical study (rat)
Guo et al., Journal of Ethnopharmacology (2024)
Angelica (Angelica archangelica) - Phytochemistry & Digestive Formula Research

A comprehensive review found Angelica archangelica shows gastroprotective and anti-inflammatory pharmacological activity

Reviewing the phytochemistry and pharmacology of Angelica archangelica (garden angelica), researchers catalogued a broad range of validated biological activities attributed to its coumarins and volatile oils, including gastroprotective, anti-inflammatory, anti-anxiety and cholinesterase-inhibitory effects reported across various in vivo and in vitro studies.

Review
Kaur & Bhatti, Phytotherapy Research (2021)
Angelica (Angelica archangelica) - Phytochemistry & Digestive Formula Research

A study found Angelica archangelica extract, alone and combined with other digestive herbs, reduced gastric ulcers in rats

Testing extracts from nine gastrointestinally active plants including Angelica archangelica, singly and in a combined commercial preparation, researchers found all extracts produced a dose-dependent reduction in indomethacin-induced gastric ulcers in rats, alongside reduced acid output and increased mucin and prostaglandin E2 secretion.

Preclinical study (rat)
Khayyal et al., Arzneimittel-Forschung (2001)
Angelica (Angelica archangelica) - Phytochemistry & Digestive Formula Research

A combination-index analysis identified Angelica archangelica and caraway as an effective anti-inflammatory pairing within a multi-herb digestive formula

Testing individual herbal components and paired combinations from a multicomponent herbal preparation (STW5, not this product's own formula) in human esophageal and intestinal cell models, researchers identified the Angelica archangelica and caraway combination as an effective anti-inflammatory pairing, helping explain the overall formula's ability to calm inflammatory signaling despite one single component stimulating it alone.

Preclinical study (human cell lines)
Ulrich-Merzenich, Welslau, Aziz-Kalbhenn, Kelber & Shcherbakova, Phytomedicine (2019)
Dandelion (Taraxacum officinale) - Digestive & GI-Protective Research

A review found dandelion's traditional digestive uses are supported by GI-protective compounds identified in its root and leaf

Reviewing dandelion's traditional folkloric use for dyspepsia, gastritis and other digestive disorders, researchers catalogued GI-protective bioactive compounds including taraxasterol, chicoric acid, chlorogenic acid and inulin, and summarized pharmacological activities relevant to dyspepsia, gastritis, ulcerative colitis and liver health reported across preclinical studies.

Review
Li, Chen & Sun-Waterhouse, Journal of Ethnopharmacology (2022)
Dandelion (Taraxacum officinale) - Digestive & GI-Protective Research

A human pilot study found dandelion leaf extract increased urination frequency and volume within hours

In a small pilot study, 17 adult volunteers took a fresh-leaf hydroethanolic dandelion extract three times over one day. Urination frequency rose significantly in the 5 hours after the first dose, providing early human evidence supporting dandelion's traditional reputation as a mild diuretic.

Human pilot study (n=17)
Clare, Conroy & Spelman, Journal of Alternative and Complementary Medicine (2009)
Dandelion (Taraxacum officinale) - Digestive & GI-Protective Research

A study found taraxasterol, a dandelion root compound, reduced inflammatory markers and eased colitis in a mouse model

Using network pharmacology to identify likely biological targets, researchers found that taraxasterol (a compound isolated from dandelion root) reduced inflammatory cytokines TNF-alpha, IL-1beta and IL-6 and eased clinical symptoms in a mouse model of acute colitis, acting in part through the PPARG and MMP3 pathways.

Preclinical study (mouse)
Chen et al., International Immunopharmacology (2019)
Combination Digestive Bitters Formulas (Multi-Herb Research)

A Cochrane review of 41 trials found several non-Chinese herbal medicines, including some of this product's own ingredients, may improve functional dyspepsia symptoms

Reviewing 41 randomized trials with 4,477 participants testing 27 different herbal medicines for functional dyspepsia, the Cochrane authors found low-to-moderate certainty evidence that artichoke, a ginger-and-artichoke combination, and Glycyrrhiza glabra (licorice), among various other herbal medicines and multi-herb formulas, each improved global dyspepsia symptoms compared with placebo, while cautioning that evidence certainty was generally low and more high-quality trials are needed.

Cochrane systematic review
Báez, Vargas, Arancibia, Papuzinski & Franco, Cochrane Database of Systematic Reviews (2023)
Combination Digestive Bitters Formulas (Multi-Herb Research)

A randomized trial found a nine-herb bitters combination significantly improved functional dyspepsia symptom scores

In 60 patients with functional dyspepsia randomized to placebo or one of two versions of a nine-herb bitters combination (STW5/Iberogast, containing bitter candy tuft, chamomile, peppermint, caraway, licorice, lemon balm, angelica, celandine and milk thistle - not this product's own formula), both herbal preparations produced significantly greater improvement in gastrointestinal symptom scores than placebo after 2 and 4 weeks.

Human RCT (n=60)
Madisch, Melderis, Mayr, Sassin & Hotz, Zeitschrift für Gastroenterologie (2001)
Combination Digestive Bitters Formulas (Multi-Herb Research)

A real-world observational study of 980 children found a multi-herb bitters preparation reduced gastrointestinal symptom scores by 76%

In a prospective observational study of 980 children treated in routine general practice for functional gastrointestinal disorders with a nine-herb bitters preparation (STW-5, not this product's own formula), average symptom scores fell from 16.1 to 3.8 over about a week of treatment, with physicians rating tolerability as good or very good for 95% of patients.

Observational study (n=980)
Michael, Bettina & Eckehard, Complementary Therapies in Medicine (2022)

Customer Reviews

4.2 out of 5 · 3 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

What is Orange Naturals Digestion Tincture and what does it do?

It's a liquid tincture combining seven traditional digestive herbs (Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian and Peppermint). Traditionally used in Herbal Medicine to help relieve digestive disturbances and flatulent dyspepsia, as a digestive tonic to help stimulate appetite and aid digestion, to help prevent nausea, and to help increase bile flow.

How do I take it?

Adults take 2 mL, 3 times per day under the tongue or in a little water, on an empty stomach (15 to 60 minutes before meals). Consult a healthcare practitioner for use beyond 1 month.

Who should NOT use this product?

Do not use if you are pregnant or breastfeeding, or if you are allergic to plants of the Asteraceae/Compositae/daisy family. Do not use if you have a bile duct or bowel obstruction, acute stomach irritation, stomach or duodenal ulcers, hypokalemia, high blood pressure, or a cardiovascular, kidney or liver disorder, or if you are taking thiazide diuretics, cardiac glycosides, corticosteroids, stimulant laxatives or other medications that may aggravate electrolyte imbalance.

Who should consult a healthcare practitioner before using it?

Consult a healthcare practitioner prior to use if you have gallstones, a peptic ulcer, a liver disorder or anemia, or if symptoms persist or worsen.

What are the non-medicinal ingredients?

40% grain alcohol and purified water.

How much is in one bottle?

Each bottle contains 100 mL (3.38 fl oz) of tincture.

Is this a Health Canada licensed product?

Yes - it is licensed as a Natural Health Product under NPN 80036529.

Where do I buy it?

Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.

7-Herb Digestive Bitters: Angelica, Artichoke, Licorice, Chamomile, Dandelion, Gentian & Peppermint100 mL (3.38 fl oz) Dropper BottleTraditionally Used in Herbal Medicine to Aid Digestion and Relieve Digestive DisturbancesHelps Increase Bile Flow and Helps Prevent Nausea

Support digestion with a 7-herb bitters tincture

Get Orange Naturals Digestion Tincture on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80036529. Traditionally used in Herbal Medicine to help relieve digestive disturbances and flatulent dyspepsia, as a digestive tonic and bitter to help stimulate appetite and aid digestion, to help prevent nausea, and to help increase bile flow. Do not use if pregnant, breastfeeding, or allergic to plants of the Asteraceae/Compositae/daisy family, or if you have certain gastrointestinal, liver, kidney or cardiovascular conditions, or are taking certain medications - see full cautions. The research summaries on this page concern these ingredients generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Consult a healthcare practitioner for use beyond 1 month. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you are pregnant or breastfeeding, or if you are allergic to plants of the Asteraceae/Compositae/Daisy family. Do not use if you have a bile duct or bowel obstruction, acute stomach irritation or inflammation, stomach or duodenal ulcers, hypokalemia, high blood pressure, or a cardiovascular, kidney or liver disorder. Do not use if you are taking thiazide diuretics, cardiac glycosides, corticosteroids, stimulant laxatives, or other medications that may aggravate electrolyte imbalance. Consult a healthcare practitioner prior to use if you have gallstones, a peptic ulcer, a liver disorder or anemia, or if symptoms persist or worsen. Avoid prolonged exposure to sunlight, ultraviolet light (UV) or UV therapy. Discontinue use if you develop symptoms of liver trouble or hypersensitivity. May cause headaches. Stop use and seek medical attention immediately if you experience dizziness, confusion, muscle weakness or pain, an abnormal heartbeat, or difficulty breathing. Do not use if the seal is broken. Keep out of reach of children.

Indications

Recommended Use or Purpose: Traditionally used in Herbal Medicine to help relieve digestive disturbances/dyspepsia. Traditionally used in Herbal Medicine to help relieve flatulent dyspepsia (carminative). Traditionally used in Herbal Medicine as a digestive tonic and bitter to help stimulate appetite and aid digestion (stomachic). Traditionally used in Herbal Medicine to help prevent nausea (anti-emetic). Used in Herbal Medicine to help increase bile flow (cholagogue).

Ingredients

Medicinal Ingredients (each mL contains): Angelica (root, Angelica archangelica), 1:4 extract, 50 mg (DHE); Artichoke (leaf, Cynara cardunculus), 1:4 extract, 50 mg (DHE); Licorice (root and stolon, Glycyrrhiza glabra), 1:5 extract, 40 mg (DHE); Chamomile (flower, Matricaria chamomilla), 1:4 extract, 25 mg (DHE); Dandelion (root, Taraxacum officinale), 1:4 extract, 25 mg (DHE); Gentian (root, Gentiana lutea), 1:4 extract, 25 mg (DHE); Peppermint (leaf, Mentha x piperita), 1:4 extract, 25 mg (DHE). Non-medicinal Ingredients: 40% grain alcohol, purified water.

Directions

Recommended Dose (Adults): Take 2 mL, 3 times per day under the tongue or in a little water, on an empty stomach (15 to 60 minutes before meals). Recommended Duration of Use: Consult a healthcare practitioner for use beyond 1 month.

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