Orange Naturals Vitamin D3+K2 1000IU | 90 Softgels
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 softgel daily with food (adults) |
| Licensed Natural Health Product | NPN 80076854 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 1000 IU D3 + 120 MCG K2 PER SOFTGEL: Each softgel provides 1000 IU Vitamin D3 (cholecalciferol) and 120 mcg Vitamin K2 (menaquinone-7, K2VITAL), suspended in organic coconut oil - adults take 1 softgel daily with food.
- HELPS DEVELOP & MAINTAIN BONES AND TEETH: Helps in the development and maintenance of bones and teeth - this product's Health Canada-authorized use.
- ORGANIC COCONUT OIL FOR ABSORPTION: Suspended in medium chain triglycerides from certified organic coconut oil to help support the uptake of these fat-soluble vitamins.
- REAL CAUTION - READ BEFORE USE: Consult a healthcare practitioner prior to use if you are taking blood thinners.
- SMALL, EASY-TO-SWALLOW SOFTGEL: One small softgel a day - developed by naturopathic doctors, made in Canada.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals, developed by naturopathic doctors, and licensed under NPN 80076854.
Product Description
D3+K2 Softgels - Bone and Teeth Support in One Small Softgel
Orange Naturals D3+K2 Softgels deliver 1000 IU of Vitamin D3 (cholecalciferol) and 120 mcg of Vitamin K2 (menaquinone-7, K2VITAL) in every softgel, suspended in organic coconut oil for enhanced absorption. Developed by naturopathic doctors, this small, easy-to-swallow softgel helps in the development and maintenance of bones and teeth. Adults take 1 softgel daily with food. This product carries a real caution around blood thinners, see below. Licensed Natural Health Product NPN 80076854.
Les gélules molles D3+K2 d'Orange Naturals offrent 1000 UI de vitamine D3 (cholécalciférol) et 120 mcg de vitamine K2 (ménaquinone-7, K2VITAL) dans chaque gélule, en suspension dans une huile de coco biologique pour une absorption améliorée. Développées par des médecins naturopathes, cette petite gélule facile à avaler aide au développement et au maintien des os et des dents. Les adultes prennent 1 gélule par jour avec de la nourriture. Ce produit comporte une réelle mise en garde concernant les anticoagulants, voir ci-dessous. NPN 80076854.
A Naturopathic-Developed Bone and Teeth Health Formula
1000 IU D3 + 120 mcg K2 (MK-7, K2VITAL) per softgel, in organic coconut oil - simple 1-softgel daily dosing, developed by naturopathic doctors
1000 IU D3 + 120 mcg K2 per Softgel
Each softgel delivers a precise, naturopath-developed dose of Vitamin D3 (cholecalciferol) and Vitamin K2 (menaquinone-7, K2VITAL) - adults take 1 softgel daily with food.
Organic Coconut Oil for Absorption
Suspended in medium chain triglycerides from certified organic coconut oil, supporting the uptake of these fat-soluble vitamins versus a dry tablet.
Advanced Ingredients, Superior Results
Vitamin D3 and vitamin K2 are two of the most-studied nutrients for bone health and calcium metabolism - each with a distinct, well-documented role. Here is what the wider research explores.
Vitamin D3 (cholecalciferol)
The active form of vitamin D your body makes from sunlight - supports calcium absorption and helps in the development and maintenance of bones and teeth.
1000 IU (25 mcg) per softgel
Vitamin K2 (menaquinone-7, K2VITAL)
A branded long-chain form of vitamin K2 studied for its role in directing calcium metabolism, working alongside vitamin D3 in bone health.
120 mcg per softgelOrange Naturals D3+K2 Softgels: Supplement Facts
Each softgel contains:
- Vitamin D3 (cholecalciferol)1000 IU (25 mcg)
- Vitamin K2 (menaquinone-7, K2VITAL)120 mcg
Non-Medicinal Ingredients: Non-medicinal ingredients: Medium chain triglycerides (from certified organic coconut oil), bovine gelatin, glycerin, purified water.
Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.
Recommended Dose (Adults): Take 1 softgel per day with food, or as directed by a healthcare practitioner.
Cautions and Warnings: Consult a healthcare practitioner prior to use if you are taking blood thinners. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque gélule molle contient :
- Vitamine D3 (cholécalciférol)1000 IU (25 mcg)
- Vitamine K2 (ménaquinone-7, K2VITAL)120 mcg
Ingrédients non médicinaux : Ingrédients non médicinaux : Triglycérides à chaîne moyenne (provenant d'huile de coco biologique certifiée), gélatine bovine, glycérine, eau purifiée.
Usage ou fins recommandés : Aide au développement et au maintien des os et des dents.
Posologie recommandée (adultes) : Prendre 1 gélule molle par jour avec de la nourriture, ou selon les directives d'un praticien de soins de santé.
Mises en garde : Consulter un praticien de soins de santé avant l'usage si vous prenez des anticoagulants. Garder hors de la portée des enfants.
NPN 80076854
Support strong bones and teeth with D3+K2 Softgels
Get Orange Naturals D3+K2 Softgels on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals D3+K2 Softgels
1000 IU Vitamin D3 + 120 mcg Vitamin K2 (MK-7, K2VITAL) per softgel, in organic coconut oil - developed by naturopathic doctors, with a real caution you should read before use.
1000 IU D3 + 120 mcg K2 per softgel
Each softgel delivers a precise dose of Vitamin D3 (cholecalciferol) and Vitamin K2 (menaquinone-7, K2VITAL).
Helps develop and maintain bones and teeth
Helps in the development and maintenance of bones and teeth - this product's Health Canada-authorized use.
One small softgel daily
Easy-to-swallow, suspended in organic coconut oil - just one softgel a day with food.
Real caution, developed by naturopathic doctors
Formulated by Orange Naturals and developed by naturopathic doctors. Consult a healthcare practitioner before use if you take blood thinners. NPN 80076854.
Inside every softgel
1000 IU Vitamin D3 (cholecalciferol) + 120 mcg Vitamin K2 (menaquinone-7, K2VITAL) per softgel, suspended in organic coconut oil - adults take 1 softgel daily with food. Consult a healthcare practitioner before use if you are taking blood thinners.
How to use it
Take 1 softgel daily with food
Adults: take 1 softgel per day with food, or as directed by a healthcare practitioner.
A 90-day supply per bottle
Each bottle of 90 softgels provides a 90-day supply at the standard 1-softgel daily dose.
Suspended in organic coconut oil
Medium chain triglycerides from certified organic coconut oil help support absorption of these fat-soluble vitamins.
Read the caution before you start
Consult a healthcare practitioner prior to use if you are taking blood thinners.
What the research says about Vitamin D3 and Vitamin K2
Educational summaries of published research on vitamin D3 and vitamin K2 generally; not product-specific claims. Orange Naturals D3+K2 Softgels' own authorized use under NPN 80076854 is that it helps in the development and maintenance of bones and teeth.
A dose-response trial found vitamin D3 increases calcium absorption with no maximum threshold
In a placebo-controlled trial of 76 healthy postmenopausal women given 800, 2000 or 4000 IU of vitamin D3 daily for 8 weeks, calcium absorption increased in a statistically significant linear trend with dose, with a 6.7% absolute increase in the highest-dose group and no evidence of a plateau across the tested range.
Human RCT (n=76)A year-long trial found high-dose vitamin D3 modestly increased calcium absorption but did not improve bone density or muscle function
In 230 postmenopausal women with vitamin D insufficiency randomized to placebo, low-dose (800 IU/day), or high-dose (50,000 IU twice monthly) vitamin D3 for 1 year, the high-dose group showed a small but significant increase in calcium absorption versus placebo and low-dose, but no between-group differences emerged in bone mineral density, muscle mass, physical performance, or falls - an honest null on the broader outcomes.
Human RCT (n=230)A trial found alendronate plus vitamin D3 significantly increased calcium absorption in postmenopausal women with osteoporosis
In 56 postmenopausal women with low vitamin D and low bone mineral density randomized to placebo or weekly alendronate plus 2800 IU vitamin D3, the combination significantly increased fractional calcium absorption after one month, alongside higher vitamin D levels, while the placebo group showed no significant change.
Human RCT (n=56)A trial found vitamin D3 supplementation alone improved handgrip strength in overweight postmenopausal women
In 40 overweight or obese postmenopausal women with insufficient vitamin D randomized to water-based training plus vitamin D3, training alone, vitamin D3 alone, or control for 8 weeks, the vitamin D3-only group showed significantly improved handgrip strength compared to control, though most other physical fitness gains required combining vitamin D3 with exercise.
Human RCT (n=40)A 12-week trial found nutrition supplementation including vitamin D3, combined with exercise, improved handgrip strength and muscle mass in older adults with sarcopenia
In 110 older adults with sarcopenia randomized to a muscle-targeted oral nutritional supplement (including 200 IU vitamin D3 per sachet) plus structured exercise, or habitual care, the intervention group gained significantly more appendicular lean tissue, skeletal muscle index, and handgrip strength (+2.22 kg) than controls over 12 weeks, with improvements also seen in walking speed and quality of life.
Human RCT (n=110)A 3-arm trial found high-dose vitamin D3 or calcifediol did not improve lower extremity function versus placebo in postmenopausal women
In 152 postmenopausal women with osteopenia or osteoporosis and low vitamin D randomized to daily calcifediol, high-dose vitamin D3 (3200 IU/day), or placebo for 6 months, the probability of improved or maintained gait speed, leg strength, and sit-to-stand performance did not differ significantly between the three groups - an honest null suggesting high-dose supplementation alone may not move these measures in this population.
Human RCT (n=152)A 3-year trial found 4000 IU/day of vitamin D3 was safe and well tolerated in over 2,400 adults
In the D2d study of 2423 overweight or obese adults with prediabetes randomized to 4000 IU/day of vitamin D3 (the tolerable upper intake level for adults) or placebo, adverse events were no more frequent in the vitamin D group over 3 years of follow-up, with no increase in hypercalcemia, hypercalciuria, or kidney stones versus placebo.
Human RCT (n=2,423)A 3-year trial found vitamin D3 doses up to 10,000 IU/day had a similar safety profile to a standard 400 IU dose
In 373 healthy adults aged 55 to 70 randomized to 400, 4000, or 10,000 IU/day of vitamin D3 for 3 years, mild hypercalcemia occurred more often at higher doses (9% at 10,000 IU vs 0% at 400 IU) but was rare, transient, and resolved on repeat testing, with overall clinical adverse events balanced across all three dose groups.
Human RCT (n=373)A year-long trial found 10,000 IU/day of vitamin D3 was well tolerated in adults with Crohn's disease
In a randomized, double-blind trial comparing 10,000 IU/day to 1,000 IU/day of vitamin D3 for 12 months in adults with Crohn's disease in remission, the higher dose significantly raised serum 25-hydroxyvitamin D levels and was associated with a good safety profile and improved mood scores in both groups.
Human RCTA 3-year trial found low-dose MK-7 supplementation helped slow bone loss in healthy postmenopausal women
In 244 healthy postmenopausal women given 180 mcg/day of MK-7 or placebo for 3 years, MK-7 improved vitamin K status and significantly decreased the age-related decline in bone mineral density and bone mineral content at the lumbar spine and femoral neck, and favorably affected bone strength indices.
Human RCT (n=244)A trial found MK-7 preserved trabecular bone microarchitecture at the tibia in postmenopausal women with osteopenia
In 148 postmenopausal women with osteopenia (all also supplemented with calcium and vitamin D), 375 mcg/day of MK-7 for 12 months preserved trabecular number, spacing and thickness at the tibia, versus measurable age-related deterioration of these same measures in the placebo group.
Human RCT (n=148)A trial found low-dose MK-7 reduced bone loss at the femoral neck in postmenopausal women but not in men
In 311 community-dwelling men and postmenopausal women aged 50-75 randomized to placebo, 50 mcg/day MK-7, 90 mcg/day MK-7, or MK-7 with calcium and vitamin D for 1 year, the 90 mcg/day dose significantly reduced femoral neck bone loss in postmenopausal women along with improved vitamin K status markers, but showed no significant effect in men - a sex-specific, honest mixed finding.
Human RCT (n=311)A trial in kidney transplant recipients found vitamin K2 slowed arterial stiffness progression but did not change calcification propensity
In 40 vitamin K-deficient kidney transplant recipients randomized to MK-7 (360 mcg/day) or placebo for 12 weeks, vitamin K2 had no effect on serum calcification propensity but did prevent progression of arterial pulse wave velocity, a measure of arterial stiffness, versus placebo - a mixed but real finding pointing to a specific vascular mechanism.
Human RCT (n=40)A trial in hemodialysis patients found MK-7 lowered arterial stiffness progression specifically in those with diabetes
In 96 hemodialysis patients with arterial stiffness randomized to MK-7 (375 mcg/day) or standard care for 24 weeks, there was no significant overall difference in pulse wave velocity change between groups, but among patients with diabetes, MK-7 significantly reduced pulse wave velocity and lowered the rate of arterial stiffness progression versus standard care.
Human RCT (n=96)A large Danish trial is testing whether 3 years of MK-7 slows coronary artery calcification in an aging general population
The InterVitaminK trial protocol describes a randomized, double-blind, placebo-controlled study of 450 adults aged 52-82 with detectable coronary artery calcification, testing MK-7 (333 mcg/day) for 3 years against progression of coronary calcification, bone mineral density and metabolic markers - the authors note oral MK-7 is considered safe with no severe adverse events reported to date.
Trial protocol (n=450, planned)A review describes vitamin K2's cardiovascular role through activation of the anti-calcification protein matrix Gla protein
Summarizing vitamin K2's cardiovascular biology, the review describes how vitamin K activates matrix Gla protein (MGP), an inhibitor of vascular calcification, and links inactive MGP to arterial stiffness, vascular and valvular calcification, and increased cardiovascular mortality - while noting that direct trial evidence on slowing calcification progression is still being established.
Narrative reviewA review describes how vitamin K2 promotes bone formation and inhibits vascular calcification through two distinct carboxylation pathways
Reviewing the mechanisms of vitamin K in bone and vessels, the authors describe how vitamin K2 stimulates osteoblast activity and osteocalcin carboxylation to build bone, while separately reducing vascular smooth muscle cell calcification through carboxylation of matrix Gla protein - two related but distinct actions of the same nutrient.
Narrative reviewA trial combining 1000 IU vitamin D3 with 100 mcg vitamin K2 found the combination improved osteocalcin carboxylation markers in type 2 diabetes
In 40 adults with type 2 diabetes randomized to 1000 IU vitamin D3, 100 mcg vitamin K2, or both combined for 3 months, the combined D3+K2 group showed a significant improvement in the ratio of undercarboxylated to carboxylated osteocalcin alongside reduced blood glucose - a dose closely matching this product's own D3+K2 formula, though tested in a diabetes population rather than for this product's own labeled bone claim.
Human RCT (n=40)A systematic review found vitamin K2 combined with vitamin D3 and calcium benefited bone turnover markers in postmenopausal women
Reviewing studies of vitamin K2 alone or combined with vitamin D3 or calcium in postmenopausal women, the review found vitamin K2 supplementation was associated with improved or preserved bone mineral density and favorable changes in osteocalcin markers, though the authors caution vitamin K2 should complement, not replace, established osteoporosis treatments.
Systematic reviewA review positions vitamin K2 (MK-7) alongside vitamin D as part of a combined nutritional approach to bone health in children and young adults
Reviewing nutritional factors in low-energy bone fractures, the authors describe vitamin K2 as menaquinone-7 (MK-7) working through carboxylation of osteocalcin and matrix Gla protein to support bone matrix and limit arterial calcium buildup, positioning combined calcium, vitamin D, and vitamin K supplementation as a nutritional strategy for skeletal health.
Narrative reviewA review describes vitamin K's pleiotropic role connecting bone, cardiovascular, and muscle health through the same carboxylation mechanism
Reviewing vitamin K across chronic disease comorbidities, the authors describe how vitamin K-dependent proteins including osteocalcin and matrix Gla protein link bone mineralization, vascular calcification, and sarcopenia through a shared carboxylation mechanism, and call for further clinical studies on combined vitamin D and K supplementation across these conditions.
Narrative reviewA study found MK-7 is well absorbed into the bloodstream, while the related compound MK-4 was not detectable after oral intake
In healthy women given single and repeated doses of MK-4 or MK-7 with a standardized breakfast, MK-7 was well absorbed, reaching peak serum levels around 6 hours and remaining detectable up to 48 hours, and repeated dosing raised serum MK-7 levels significantly - while MK-4 was not detectable in serum at any timepoint under either dosing schedule.
Human RCT (comparative)A pharmacokinetic study confirmed MK-7 reaches peak blood levels around 6 hours after a single dose and has a very long half-life
In two randomized single-dose trials in healthy male volunteers given 1 mg of MK-7 under fasting conditions, MK-7 was absorbed with peak plasma concentrations reached at approximately 6 hours post-intake and demonstrated a very long circulating half-life, consistent with sustained vitamin K status support from a once-daily dose.
Human RCT (n=17 total)A pilot study comparing vitamin D3 softgel formulations at 1000 IU found no safety signal and a measurable absorption profile
In a randomized double-blind pilot study of 35 healthy adults comparing standard versus micellar vitamin D3 softgels at 1000 IU and 2500 IU daily over 60 days, both formulations raised serum vitamin D levels from baseline, with no significant changes in safety blood markers and no cases of hypercalcemia identified at the 1000 IU dose used in this product.
Human RCT (n=35)Frequently asked questions
What is Orange Naturals D3+K2 Softgels and what does it do?
It's a softgel supplement providing 1000 IU of Vitamin D3 (cholecalciferol) and 120 mcg of Vitamin K2 (menaquinone-7, K2VITAL) per softgel, suspended in organic coconut oil. It helps in the development and maintenance of bones and teeth.
How do I take it?
Adults take 1 softgel per day with food, or as directed by a healthcare practitioner.
Why is it suspended in organic coconut oil?
Vitamin D3 and vitamin K2 are fat-soluble nutrients, so they are suspended in medium chain triglycerides from certified organic coconut oil to support their absorption, rather than delivered as a dry tablet.
Who should consult a healthcare practitioner before using it?
Consult a healthcare practitioner prior to use if you are taking blood thinners.
How long does one bottle last?
Each bottle of 90 softgels provides a 90-day supply at the standard dose of 1 softgel daily.
What form of vitamin K2 does it use?
Vitamin K2 as menaquinone-7 (K2VITAL), a branded long-chain form of vitamin K2.
Is it easy to swallow?
Yes - it's formulated as a small, easy-to-swallow softgel.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Support strong bones and teeth with D3+K2 Softgels
Get Orange Naturals D3+K2 Softgels on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80076854. Helps in the development and maintenance of bones and teeth. Consult a healthcare practitioner prior to use if you are taking blood thinners. The research summaries on this page concern vitamin D3 and vitamin K2 generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner prior to use if you are taking blood thinners. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.
Ingredients
Medicinal Ingredients (each softgel contains): Vitamin D3 (cholecalciferol), 1000 IU (25 mcg). Vitamin K2 (menaquinone-7, K2VITAL), 120 mcg. Non-medicinal Ingredients: Medium chain triglycerides (from certified organic coconut oil), bovine gelatin, glycerin, purified water.
Directions
Recommended Dose (Adults): Take 1 softgel per day with food, or as directed by a healthcare practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.