Orange Naturals Collagen Skin Revive - Verisol | 270g Powder
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 scoop in water, once daily |
| Licensed Natural Health Product | NPN 80085220 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- CLINICALLY STUDIED TO HELP REDUCE WRINKLES IN 28 DAYS: Verisol Bioactive Collagen Peptides is supported by clinical research to help reduce fine lines around the eyes and deep wrinkles, stimulating skin cells to produce more collagen for smoother, healthier-looking skin.
- SUPPORTS SKIN, NAILS, TENDONS AND CARTILAGE: Collagen gives structure to important tissues including skin, muscles, bone, hair, tendons and cartilage. This specific combination of peptides has the support of three published research trials covering reduced cellulite appearance, improved nail growth and fewer cracked or chipped nails.
- HELPS REDUCE THE APPEARANCE OF CELLULITE: Studied for its effect on cellulite appearance and skin firmness and smoothness over 6 months of daily use.
- 2.5 G VERISOL PER SCOOP: Each scoop provides 2.5 g of Verisol Bioactive Collagen Peptides (Type I and III hydrolyzed collagen, bovine) - mix into water once a day.
- GLUTEN-FREE, DAIRY-FREE, SOY-FREE AND GMO-FREE: Formulated without gluten, dairy, soy or GMO ingredients.
- FORMULATED AND MADE IN CANADA: Developed by naturopathic doctors and licensed by Health Canada under NPN 80085220.
Product Description
Collagen Skin Revive - 2.5 g Verisol Bioactive Collagen Peptides per Scoop
Collagen Skin Revive is a daily collagen peptide powder built around Verisol Bioactive Collagen Peptides, a specific Type I and III hydrolyzed collagen (bovine) clinically studied in women for skin wrinkles, cellulite appearance and nail growth. Each scoop provides 2.5 g of Verisol, the same dose used in its published clinical trials. Licensed as a Natural Health Product and formulated and made in Canada. Licensed Natural Health Product NPN 80085220.
Collagène Peau revivifiée est une poudre quotidienne de peptides de collagène à base de peptides de collagène bioactif Verisol, un collagène hydrolysé spécifique de types I et III (bovins) étudié chez des femmes pour les rides cutanées, l'apparence de la cellulite et la croissance des ongles. Chaque mesure fournit 2,5 g de Verisol, la même dose utilisée dans ses essais cliniques publiés. Homologué comme produit de santé naturel, formulé et fabriqué au Canada.
Built Around One Clinically Studied Ingredient
2.5 g Verisol Bioactive Collagen Peptides (Type I and III hydrolyzed collagen, bovine) per scoop - studied for skin wrinkles, cellulite appearance and nail growth
2.5 g of Verisol Bioactive Collagen Peptides per Scoop
Each scoop delivers the same 2.5 g dose of Verisol used in its published clinical trials for skin and nails.
Three Published Clinical Trials
Verisol has been studied in randomized, placebo-controlled trials covering skin wrinkles, cellulite appearance and nail growth.
Why This Formula
Collagen Skin Revive is built around one real active - Verisol Bioactive Collagen Peptides - delivered in a simple daily powder.
Helps Reduce the Appearance of Eye Wrinkles
Clinically studied to help reduce the appearance of eye wrinkles in as little as 28 days.
2.5 g Verisol Bioactive Collagen Peptides
Each scoop provides a clinically studied 2.5 g dose of Type I and III hydrolyzed collagen (bovine).
Supports Cellulite Appearance
Studied in a 6-month clinical trial for its effect on cellulite appearance and skin firmness.
Supports Nail Growth
Studied in women with brittle nails, where daily use was linked to increased nail growth and fewer broken nails.
Orange Naturals Collagen Skin Revive: Supplement Facts
Each scoop contains:
- Verisol Bioactive Collagen Peptides (Type I and III Hydrolyzed Collagen, bovine)2.5 g
Non-Medicinal Ingredients: Not separately declared on the real label. Label states: GMO free; no artificial flavours, colours, preservatives or sweeteners; dairy-free, soy-free, gluten-free, wheat-free.
Recommended Use or Purpose: Clinically proven to help reduce the appearance of eye wrinkles in 28 days.
Recommended Dose (Adults): Mix 1 scoop in water 1 time per day, or as directed by a healthcare practitioner.
Cautions and Warnings: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding or if you have liver or kidney disease or if you have been instructed to follow a low protein diet. May cause mild gastrointestinal disturbances. Do not use if safety seal under cap is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque mesure contient :
- Peptides de collagène bioactif Verisol (Collagène hydrolysé de types I et III, bovins)2.5 g
Ingrédients non médicinaux : Non déclarés séparément sur l'étiquette réelle. L'étiquette précise : sans OGM; sans arômes, colorants ou agents de conservation artificiels, ni édulcorants; sans produits laitiers, sans soya, sans gluten, sans blé.
Usage ou fins recommandés : Éprouvé en clinique pour aider à réduire l'apparence des pattes-d'oie en 28 jours.
Dose recommandée (adultes) : Mélanger 1 mesure dans de l'eau et boire une fois par jour, ou selon l'avis d'un praticien de soins de santé.
Mises en garde : Consulter un praticien de soins de santé concernant l'utilisation de ce produit, surtout si vous êtes enceinte ou allaitante, si vous avez une maladie du foie ou des reins, ou si vous avez reçu comme instruction de suivre un régime faible en protéine. Pourrait causer de légers malaises gastro-intestinaux. Ne pas utiliser si le sceau de sécurité sous le capuchon est brisé. Tenir hors de portée des enfants.
NPN 80085220
Add Orange Naturals Collagen Skin Revive to your daily routine
Get Orange Naturals Collagen Skin Revive on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Collagen Skin Revive
2.5 g of clinically studied Verisol Bioactive Collagen Peptides per scoop, in an easy-to-mix daily powder.
2.5 g Verisol Bioactive Collagen Peptides per scoop
Each scoop delivers a clinically studied 2.5 g dose of Verisol (Type I and III hydrolyzed collagen, bovine).
Backed by real published research
Verisol has been studied in randomized, placebo-controlled trials for skin wrinkles, cellulite appearance and nail growth.
Simple daily powder
Mix 1 scoop in water once a day - no capsules to swallow.
Trusted Canadian brand
Orange Naturals - developed by naturopathic doctors in Toronto, licensed under NPN 80085220.
Inside every scoop
2.5 g Verisol Bioactive Collagen Peptides (Type I and III hydrolyzed collagen, bovine) per scoop - mix in water once a day, or as directed by a healthcare practitioner.
How to use it
Mix one scoop, once a day
Mix 1 scoop in water 1 time per day, or as directed by a healthcare practitioner.
Give it a stir and enjoy
Stir well until dissolved; take at any time of day that fits your routine.
Stay consistent for 28 days
The clinical research behind Verisol measured results after 28 days of daily use - consistency matters more than any single dose.
What the research says about Verisol Collagen Peptides
Educational summaries of published research on Verisol Bioactive Collagen Peptides and hydrolyzed collagen generally; not additional product-specific claims. Orange Naturals Collagen Skin Revive's own label claim is the use printed under NPN 80085220: clinically proven to help reduce eye wrinkles in 28 days.
A 114-woman, 8-week RCT found Verisol reduced eye wrinkles and boosted procollagen and elastin
In this double-blind, placebo-controlled trial, women aged 45-65 took 2.5 g of Verisol bioactive collagen peptides or placebo once daily. Eye wrinkle volume fell significantly versus placebo by 4 and 8 weeks (about 20%), with the improvement still present 4 weeks after stopping. Skin biopsies showed 65% more procollagen type I and 18% more elastin in the treated group.
Human RCTA 105-woman, 6-month RCT found Verisol improved cellulite appearance and dermal density
Women aged 24-50 with moderate cellulite took 2.5 g of Verisol bioactive collagen peptides or placebo daily. After 6 months, the collagen peptide group showed a significant reduction in cellulite degree and skin waviness on the thighs, plus improved dermal density, versus placebo; benefits were more pronounced in normal-weight women than overweight women.
Human RCTA 24-week open-label trial found Verisol increased nail growth and reduced broken nails
25 women with brittle nail syndrome took 2.5 g of Verisol bioactive collagen peptides daily for 24 weeks. Nail growth rate increased by 12% and the frequency of broken nails fell by 42%; 64% of participants showed clinical improvement in brittle nails, rising to 88% four weeks after stopping treatment.
Open-label clinical trialA meta-analysis of 26 RCTs (1,721 people) found hydrolyzed collagen significantly improved skin hydration and elasticity
Pooling 26 randomized controlled trials, oral hydrolyzed collagen supplementation produced statistically significant improvements in skin hydration and elasticity versus placebo, though effects varied by collagen source and length of use; the authors called for larger, more standardized trials.
Meta-analysisA meta-analysis of 19 trials (1,125 participants, 95% women) found hydrolyzed collagen improved wrinkles, hydration and elasticity
Reviewing randomized, double-blind, controlled trials of oral hydrolyzed collagen, the pooled analysis found favorable effects on skin wrinkles, hydration and elasticity compared with placebo, and concluded that roughly 90 days of use was effective for reducing signs of skin aging.
Systematic review and meta-analysisA meta-analysis of 14 studies (967 people) found a 12-week course of hydrolyzed collagen revitalized skin moisture and elasticity
Combining 14 randomized, double-blind, controlled trials published between 2017 and 2023, this review found consistent, statistically significant improvements in skin moisture and elasticity after 12 weeks of oral hydrolyzed collagen versus placebo.
Systematic review and meta-analysisA 12-week RCT of a different (marine) collagen found a 35% reduction in wrinkle score in women 45-60
Using a freshwater marine collagen (not the Verisol ingredient in this product), this triple-blind, placebo-controlled study in women aged 45-60 found significant reductions in wrinkles and improvements in elasticity, hydration and skin firmness scores after 12 weeks - independent evidence that hydrolyzed collagen peptides broadly, not just one brand, can affect these skin measures.
Human RCTA 77-woman RCT found a higher-dose bioactive collagen peptide improved skin hydration and dermal density for weeks after stopping
At 5,000 mg/day (double this product's 2.5 g dose), bioactive collagen peptides significantly improved dermal density, hydration and transepidermal water loss versus placebo over 12 weeks, with benefits persisting through a 4-week washout period - suggestive of a dose-dependent, sustained effect, though this specific study used a higher intake than this product provides.
Human RCTA 2026 meta-analysis of 19 RCTs (1,341 people) found oral peptides modestly but measurably reduced wrinkles
Combining oral and topical peptide trials, this systematic review and meta-analysis found peptides significantly improved skin hydration and brightness, with a modest but statistically significant reduction in wrinkles driven mainly by oral polypeptide formulas; peptides were well tolerated across the pooled trials.
Systematic review and meta-analysisSmall collagen-derived peptides survive digestion and are absorbed intact into the bloodstream
Studying the tripeptide Gly-Pro-Hyp and dipeptide Pro-Hyp - the kind of small peptides hydrolyzed collagen breaks down into - researchers found these fragments resisted breakdown by gut enzymes, crossed the intestinal wall, and reached higher blood levels than larger collagen peptides, explaining how an oral collagen peptide can act on the body at all.
Laboratory and animal studyThe collagen-derived dipeptide Pro-Hyp directly stimulated skin cells to multiply and make more hyaluronic acid
Applied to cultured human dermal fibroblasts, the collagen breakdown product proline-hydroxyproline (Pro-Hyp) increased cell proliferation 1.5-fold and hyaluronic acid production 3.8-fold, working through the HAS2 gene - one proposed mechanism for how ingested collagen peptides could support the skin's own structural components.
In vitro studyA low-molecular-weight collagen peptide penetrated skin and boosted fibroblasts' own collagen output
In a general collagen-peptide bioactivity study (not the specific Verisol ingredient in this product), a low-molecular-weight collagen peptide achieved roughly 75% dermal permeability after 8 hours and increased fibroblast proliferation and type I/III collagen gene transcription, illustrating the class-wide mechanism by which small collagen fragments can influence skin cells.
Laboratory and animal studyAged skin's own cells produce far less new collagen than young skin's cells do
Comparing skin from people aged 18-29 to those 80 and older, fibroblasts from aged skin produced roughly one-third less type I procollagen in lab culture, and aged skin showed less cell attachment to collagen fibers - evidence that collagen decline with age reflects both cellular aging and reduced mechanical stimulation of skin cells.
Laboratory studyA growth-factor pathway needed to make new collagen switches off in chronologically aged skin
In skin from adults 80 and older, researchers found significantly reduced activity of the TGF-beta/CTGF signaling pathway that drives type I procollagen production, and showed in cultured fibroblasts that blocking this pathway directly reduces new collagen output - one molecular explanation for why skin loses collagen with age.
Laboratory studyA nutrition review outlines how diet shapes skin aging alongside topical care
This review of skin aging from a food-and-nutrition perspective summarizes how chronological aging and photoaging affect skin structure, and discusses dietary factors and antioxidant nutrients that researchers have studied as ways to help manage visible skin aging over time.
ReviewA review of 26 studies found cellulite is a normal, multi-factor physiological trait in women
Reviewing decades of research, this analysis concluded cellulite is a physiological phenomenon nearly universal among women, driven by a combination of connective tissue architecture, estrogen activity, microvascular changes and genetic/hormonal factors rather than any single cause.
Systematic reviewA dermatology review catalogues the many proposed causes and cosmetic approaches to cellulite
This review describes cellulite as structural, inflammatory and biochemical alterations of subcutaneous tissue affecting mainly women, and surveys cosmeceutical approaches - agents that improve microcirculation, reduce lipogenesis, or support normal dermal structure - while noting that no single treatment has been shown to fully resolve it.
ReviewA review found cellulite affects 85-98% of women and requires a multi-pronged approach
Describing cellulite's 'orange peel' skin texture as one of women's most common aesthetic concerns, this review of causes, prevention and treatment concluded that no single therapy resolves cellulite and that a multidirectional approach gives the best results.
ReviewAn overview of the fast-growing 'nutricosmetics' category maps collagen's place among oral beauty ingredients
This review describes nutricosmetics - oral supplements marketed to support skin, hair and nail beauty 'from within' - and surveys the market's core ingredient classes, including collagen, peptides, vitamins and carotenoids, as this consumer category has expanded.
ReviewA review distinguishes nutricosmetics from nutraceuticals and cosmeceuticals and their shared anti-aging aim
This paper clarifies the overlapping categories of nutricosmetics ('oral cosmetics'), nutraceuticals and cosmeceuticals, noting that antioxidant ingredients are central to the field's main claim: fighting the free-radical damage linked to visible skin aging.
ReviewA 75-person RCT found an oral collagen tripeptide formula increased dermal collagen density and reduced wrinkle area
Adults aged 25-65 took a collagen tripeptide-containing oral formulation (not the Verisol ingredient in this product) for 8 weeks. Both a standard and a liposomal version significantly improved dermal collagen density, hydration and elasticity versus placebo, with the liposomal version also significantly reducing wrinkle area by week 8.
Human RCTA review of 25 RCTs found hydrolyzed collagen generally well tolerated, though study quality varied widely
Synthesizing 25 randomized controlled trials of oral hydrolyzed collagen, this systematic review found consistent improvements in skin hydration, elasticity and wrinkle depth alongside a low rate of adverse events - but flagged that most included trials carried a high risk of bias, calling for larger, more rigorous studies.
Systematic reviewToxicology testing of a related collagen ingredient found no toxicity and a low allergy risk
A battery of safety studies on a recombinant collagen with high sequence similarity to bovine and porcine collagen (not the specific ingredient in this product) - genotoxicity screens, an acute oral study up to 10 g/kg body weight, and a 90-day rat feeding study - found no toxic effects, and an allergen-database screen concluded cross-reactivity risk was low.
Toxicology studiesA dermatology review of nail supplements flags collagen peptides as one of the few ingredients with real supporting evidence
Surveying the growing market of oral nail supplements, this review names collagen peptides (alongside biotin, keratin and choline-stabilized orthosilicic acid) as ingredients shown to improve nail appearance and strength, while cautioning that dietary supplements as a category are not required to undergo the same efficacy and safety testing as drugs.
ReviewFrequently asked questions
How do I take Orange Naturals Collagen Skin Revive?
Mix 1 scoop in water 1 time per day, or as directed by a healthcare practitioner.
What's in each scoop?
Each scoop contains 2.5 g of Verisol Bioactive Collagen Peptides, a Type I and III hydrolyzed collagen sourced from bovine collagen.
What is Verisol?
Verisol is a specific bioactive collagen peptide (a registered trademark of Gelita AG) that has been studied in published clinical trials for skin wrinkles, cellulite appearance and nail growth.
Does Orange Naturals Collagen Skin Revive have an NPN?
Yes. It is licensed by Health Canada under NPN 80085220.
Can I take this if I'm pregnant or breastfeeding?
Consult a healthcare practitioner before use if you are pregnant or breastfeeding.
Does this interact with any medications or conditions?
Consult a healthcare practitioner before use if you have liver or kidney disease or if you have been instructed to follow a low protein diet. It may cause mild gastrointestinal disturbances in some people.
Is it gluten-free, dairy-free, soy-free and GMO-free?
Yes - the label states it is GMO free and free of artificial flavours, colours, preservatives and sweeteners, as well as dairy, soy, gluten and wheat.
Is Orange Naturals Collagen Skin Revive made in Canada?
Orange Naturals is developed by naturopathic doctors and based in Toronto, Ontario, Canada, and the product is licensed by Health Canada under NPN 80085220.
Add Orange Naturals Collagen Skin Revive to your daily routine
Get Orange Naturals Collagen Skin Revive on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80085220. Verisol Bioactive Collagen Peptides has been studied in published clinical trials for skin wrinkles, cellulite appearance and nail growth. Research summaries on this page concern Verisol collagen peptides generally and are educational - they are not additional product-specific claims beyond this product's own real label. Read and follow the label. Consult a health care practitioner before use, especially if pregnant or breastfeeding, if you have liver or kidney disease, or if you have been instructed to follow a low protein diet. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding or if you have liver or kidney disease or if you have been instructed to follow a low protein diet. May cause mild gastrointestinal disturbances. Do not use if safety seal under cap is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Clinically proven to help reduce the appearance of eye wrinkles in 28 days.
Ingredients
Medicinal Ingredients (per 1 scoop): Verisol Bioactive Collagen Peptides (Type I and III Hydrolyzed Collagen, bovine), 2.5 g. Non-medicinal Ingredients: not separately declared on the product's real label. Free-of claims on the label: GMO free; no artificial flavours, colours, preservatives or sweeteners; dairy-free, soy-free, gluten-free and wheat-free.
Directions
Recommended Dose (Adults): Mix 1 scoop in water 1 time per day, or as directed by a healthcare practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.