Orange Naturals Collagen Active Joints - FORTIGEL | 150g Powder
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 scoop (5 g), 1 to 2 times daily in water or juice |
| Licensed Natural Health Product | NPN 80112926 |
| Quality Standards | Developed by naturopathic doctors - crafted in Canada |
| Country | Made in Canada  |
About this item
- 5 G OF FORTIGEL TYPE I & III COLLAGEN PEPTIDES PER SCOOP: Each 5 g scoop of this unflavoured powder provides 5 g of Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine) - take 1 scoop, 1 to 2 times per day, or as directed by a healthcare practitioner.
- HELPS REDUCE JOINT PAIN ASSOCIATED WITH OSTEOARTHRITIS: The recommended use authorized on this product's Health Canada licence (NPN 80112926): helps to reduce joint pain associated with osteoarthritis.
- SOURCE OF LYSINE FOR COLLAGEN FORMATION: Type I and III collagen peptides naturally supply the essential amino acid lysine, a building block your body uses to help form its own collagen.
- ONE INGREDIENT, UNFLAVOURED, EASY TO MIX: No binders, fillers, artificial colours, flavours or sweeteners - just Fortigel collagen peptides, dissolved easily into water, juice, coffee, or your usual routine.
- DEVELOPED BY NATUROPATHIC DOCTORS: Formulated by Orange Naturals' team of naturopathic doctors, crafted in Canada.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated and made in Canada by Orange Naturals and licensed under NPN 80112926.
Product Description
Collagen Active Joints - 5 g FORTIGEL Type I & III Collagen Peptides per Scoop
Collagen Active Joints is an unflavoured, single-ingredient collagen powder built around FORTIGEL Bioactive Collagen Peptides, a specific hydrolyzed Type I and III collagen from Orange Naturals' team of naturopathic doctors. Each 5 g scoop delivers 5 g of Fortigel collagen peptides, which naturally supply the essential amino acid lysine to help support your body's own collagen formation. Helps to reduce joint pain associated with osteoarthritis. No binders, fillers, artificial colours, flavours or sweeteners - just one real ingredient, crafted in Canada and licensed as a Natural Health Product. Licensed Natural Health Product NPN 80112926.
Collagen Active Joints est une poudre de collagène non aromatisée, à ingrédient unique, élaborée à partir de FORTIGEL Bioactive Collagen Peptides, un collagène hydrolysé spécifique de types I et III mis au point par l'équipe de naturopathes d'Orange Naturals. Chaque cuillerée de 5 g fournit 5 g de peptides de collagène Fortigel, qui apportent naturellement l'acide aminé essentiel lysine pour aider à soutenir la formation du collagène par l'organisme. Aide à réduire les douleurs articulaires associées à l'ostéoarthrite. Sans liants, agents de remplissage, colorants, aromatisants ou édulcorants artificiels - un seul ingrédient réel, élaboré au Canada et homologué comme produit de santé naturel.
Built Around One Real Active
5 g Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine) per scoop - unflavoured, no fillers
5 g of FORTIGEL Collagen Peptides per Scoop
Each 5 g scoop delivers 5 g of Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine) - take 1 scoop, 1 to 2 times daily, or as directed by a healthcare practitioner.
One Real Ingredient, No Fillers
No binders, fillers, artificial colours, flavours or sweeteners - unflavoured and easy to mix into water, juice, or your usual daily drink.
Why This Formula
Collagen Active Joints is built around one real active - FORTIGEL Type I and III collagen peptides - delivered in an unflavoured, easy-to-mix daily scoop.
Joint Comfort Support
Helps to reduce joint pain associated with osteoarthritis - this product's Health Canada-authorized use.
5 g FORTIGEL Collagen Peptides per Scoop
Each 5 g scoop delivers 5 g of Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine).
Source of Lysine for Collagen Formation
Type I and III collagen peptides naturally supply the essential amino acid lysine, which your body uses to help form its own collagen.
Naturopath-Developed, Made in Canada
Formulated by Orange Naturals' team of naturopathic doctors and crafted in Canada, licensed under NPN 80112926.
Orange Naturals Collagen Active Joints: Supplement Facts
Each scoop (5 g) contains:
- Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine)5 g
Non-Medicinal Ingredients: None.
Recommended Use or Purpose: Helps to reduce joint pain associated with osteoarthritis. Source of the essential amino acid lysine to help in collagen formation.
Recommended Dose (Adults): Take one scoop (5 g), one to two times per day in water or juice, or as directed by a healthcare practitioner. Recommended Duration of Use: Use for a minimum of 5 months to see beneficial effects.
Cautions and Warnings: As with any natural health product, consult a healthcare practitioner before use of this product if you are pregnant or breastfeeding. May cause mild gastrointestinal disturbances. Do not use if the safety seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque cuillerée (5 g) contient :
- Collagène hydrolysé - FORTIGEL, peptides de collagène bioactifs, types I et III (bovin)5 g
Ingrédients non médicinaux : Aucun.
Usage ou fins recommandés : Aide à réduire les douleurs articulaires associées à l'ostéoarthrite. Source de l'acide aminé essentiel lysine pour aider à la formation du collagène.
Dose recommandée (adultes) : Prendre une cuillerée (5 g), une à deux fois par jour dans de l'eau ou du jus, ou selon l'avis d'un praticien de soins de santé. Durée d'utilisation recommandée : Utiliser pendant au moins 5 mois afin de constater des effets bénéfiques.
Mises en garde et avertissements : Comme avec tout produit de santé naturel, consultez un praticien de soins de santé avant l'utilisation de ce produit si vous êtes enceinte ou allaitante. Peut causer des troubles gastro-intestinaux légers. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants.
NPN 80112926
Add Orange Naturals Collagen Active Joints to your daily routine
Get Orange Naturals Collagen Active Joints on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Collagen Active Joints
5 g of FORTIGEL Type I and III collagen peptides per scoop, unflavoured, with no fillers or added sweeteners.
5 g FORTIGEL collagen peptides per scoop
Each 5 g scoop delivers 5 g of Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine).
Helps reduce joint pain associated with osteoarthritis
The Health Canada-authorized use on this product's own NPN (80112926) - not a generic joint-supplement claim.
One real ingredient, unflavoured
No binders, fillers, artificial colours, flavours or sweeteners - dissolves easily into water, juice, or coffee.
Developed by naturopathic doctors, made in Canada
Orange Naturals - formulated by naturopathic doctors and crafted in Canada, licensed under NPN 80112926.
Inside every scoop
5 g Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine) per 5 g scoop - take 1 scoop, 1 to 2 times daily, or as directed by a healthcare practitioner.
How to use it
Take it by the scoop
Adults take 1 scoop (5 g), 1 to 2 times per day in water or juice, or as directed by a healthcare practitioner.
Mix it into whatever you're already drinking
Unflavoured and easy to blend into coffee, water, juice or a smoothie - it won't change the taste of your routine.
Give it time
Use for a minimum of 5 months to see beneficial effects.
What the research says about Collagen Peptides
Educational summaries of published research on hydrolyzed/specific collagen peptides and the amino acids (including lysine) they supply; not product-specific claims. Orange Naturals Collagen Active Joints' own label claim is the use authorized under NPN 80112926: helps to reduce joint pain associated with osteoarthritis, and is a source of the essential amino acid lysine to help in collagen formation.
A 2025 RCT found combined undenatured type II and hydrolysed collagen no better than placebo for knee osteoarthritis
In this randomised, double-blind, placebo-controlled trial of 68 patients with knee osteoarthritis, both the collagen-supplement group and the placebo group improved significantly in pain and function over 12 weeks, with no significant difference between groups - an honest null result for this particular combination product.
Human RCTAn 8-week RCT found a Type I, II and III collagen blend improved knee osteoarthritis pain and quality of life
In 31 adults with Grade 2-3 knee osteoarthritis, eight weeks of a collagen supplement containing type 1, 2 and 3 collagen significantly improved pain (VAS), WOMAC, knee outcome scores, and several quality-of-life measures compared with placebo.
Human RCTA companion 8-week RCT found the same collagen blend improved pain and quality of life in patients with meniscopathy
In 32 patients with meniscal tears, eight weeks of supplementation with a type I, II and III collagen product significantly improved pain, quality-of-life, kinesiophobia and foot-function scores versus placebo, with a significant improvement in leg strength as well.
Human RCTCollagen hydrolysate stimulated chondrocytes to make more type II collagen in a lab study
In cultured bovine cartilage cells, adding collagen hydrolysate to the growth medium caused a dose-dependent increase in type II collagen production, while native collagen and a non-collagen protein hydrolysate had no such effect - suggesting a feedback mechanism in cartilage's own collagen turnover.
In vitro studyA literature review found collagen hydrolysate is absorbed intestinally and accumulates in cartilage
Reviewing preclinical and clinical research through 2006, the authors found collagen hydrolysate to be safe across several open-label and double-blind studies, with orally administered collagen hydrolysate shown to be absorbed and to accumulate in cartilage tissue, stimulating chondrocyte matrix synthesis.
ReviewAn early review outlined collagen hydrolysate's proposed role in bone and joint disease
This review summarized the rationale for collagen hydrolysate as a joint-health nutrient, describing its absorption, potential cartilage-supportive mechanisms, and the clinical studies available at the time in patients with osteoarthritis and other joint conditions.
ReviewA pharmacokinetic study measured how efficiently individual collagen peptides are absorbed orally
In rats given collagen di- and tripeptides (Gly-Pro, Pro-Hyp, Gly-Pro-Hyp) orally and intravenously, the absolute oral bioavailability of Pro-Hyp was 19.3% and of Gly-Pro-Hyp was 4.4%, with both showing 'flip-flop' absorption kinetics consistent with transporter-mediated uptake.
Animal studyFood-derived collagen peptides were directly identified in human blood after oral gelatin hydrolysate ingestion
Healthy volunteers who ingested gelatin hydrolysates showed a significant rise in plasma hydroxyproline-containing peptides, peaking 1-2 hours after ingestion; the major peptide identified was Pro-Hyp, with smaller amounts of several other hydroxyproline-containing peptides also detected.
Human studyA systematic review found collagen derivatives showed mixed, generally low-to-moderate quality evidence for osteoarthritis symptoms
Reviewing 8 randomized trials of collagen hydrolysate, gelatine, and undenatured collagen, the authors found some studies showed pain benefit versus placebo or glucosamine sulphate, but pooled results for collagen hydrolysate versus placebo did not reach significance for pain, and concluded there is insufficient evidence yet to recommend generalized use.
Systematic reviewA 12-week RCT found specific collagen peptides reduced activity-related knee pain in young active adults
In 180 physically active men and women aged 18-30 with exercise-related knee pain, 5 g daily of specific collagen peptides led to a significantly greater reduction in exercise-induced knee pain than placebo, confirmed by both participant and physician assessment.
Human RCTCollagen peptide supplementation improved function, pain and mental health scores over 6-9 months in active adults
In a double-blind RCT with three treatment arms (placebo, 10 g/day, or 20 g/day collagen peptides), 10 g/day improved activities-of-daily-living and pain scores at 6 months, particularly in high-frequency exercisers, and improved mental health component scores over 3-9 months.
Human RCTA 24-week RCT found collagen hydrolysate reduced activity-related joint pain in student athletes
In 147 varsity and club athletes with no diagnosed joint disease, 10 g daily of collagen hydrolysate significantly reduced joint pain at rest, walking, standing, carrying and lifting compared with placebo, with a more pronounced effect in the subgroup with knee arthralgia.
Human RCTA meta-analysis found collagen ranked among the more promising dietary supplements for knee osteoarthritis
Comparing several dietary supplements across the OA literature, this systematic review and meta-analysis found collagen hydrolysate and a small number of other supplements showed the most consistent, though still moderate-quality, evidence of benefit for osteoarthritis symptoms.
Meta-analysisA review examined collagen supplementation's effect on pain in people with self-reported knee pain
This review assessed the available evidence on oral collagen supplementation for pain scores in healthy individuals reporting knee pain, summarizing effect sizes and study quality across the identified trials.
ReviewAn updated meta-analysis of 11 RCTs (870 patients) found collagen supplementation significantly improved knee osteoarthritis pain and function
Pooling data from 451 patients on collagen supplements and 419 on placebo, this 2024 meta-analysis found statistically and clinically significant improvements in both function and pain scores favouring collagen supplementation.
Meta-analysisA review detailed how the enzyme lysyl oxidase cross-links lysine residues to help form mature collagen
This review describes how lysyl oxidase enzymes catalyze the oxidative deamination of lysine and hydroxylysine residues in collagen, the essential first step toward the cross-linking that gives mature collagen its structural strength in the extracellular matrix.
ReviewA biochemistry review outlined lysyl hydroxylase's role in collagen cross-linking
This review discusses how lysyl hydroxylase 2 forms hydroxylysine-derived cross-links in collagen's telopeptides, a modification central to collagen network stability and turnover.
ReviewA rat study found lysine supplementation reversed collagen deficits caused by a low-quality protein diet
Rats fed a low-lysine gluten diet showed reduced wound collagen deposition and slower healing compared with a casein diet; adding lysine to the gluten diet reversed this effect, restoring collagen deposition toward normal levels.
Animal studyA 12-month RCT found specific collagen peptides increased bone mineral density in postmenopausal women
In 131 postmenopausal women with reduced bone mineral density, daily oral specific collagen peptides significantly increased bone mineral density at the spine and femoral neck compared with placebo, alongside a favourable shift in bone formation and resorption markers.
Human RCTA 4-year follow-up found the bone mineral density benefit of specific collagen peptides was sustained long-term
In an open-label follow-up of postmenopausal women with osteopenia or osteoporosis who continued specific collagen peptide supplementation, bone mineral density continued to show clinically relevant increases at the spine and femoral neck after four total years.
Human studyA 2026 scoping review found collagen supplementation shows promise for bone turnover and density, especially in postmenopausal women
Reviewing 15 studies on oral collagen supplementation and skeletal outcomes, this scoping review found improvements in bone turnover markers and bone mineral density at several sites, particularly in postmenopausal women, though it noted heterogeneity across study designs.
Scoping reviewA 13-week RCT comparing enzymatic hydrolysed collagen to glucosamine sulphate found both well tolerated
In 100 adults with knee osteoarthritis, daily enzymatic hydrolysed collagen showed superior pain and quality-of-life improvements over glucosamine sulphate, with a similar incidence of adverse events between groups and both treatments described as well tolerated.
Human RCTA randomized trial specifically evaluating efficacy and safety found collagen hydrolysate safe for osteoarthritis symptoms
This randomized controlled trial was designed to assess both the efficacy and the safety of collagen hydrolysate as a food ingredient in people with joint symptoms, reporting on tolerability alongside symptom outcomes over the study period.
Human RCTA review of osteoarthritis nutraceuticals noted hydrolyzed collagen's generally favourable safety profile
This review of micronutrient and nutraceutical options for osteoarthritis, including undenatured and hydrolyzed collagen preparations, noted that most nutritional interventions in this category carry a favourable safety profile relative to standard pharmacologic options.
ReviewFrequently asked questions
How do I take Orange Naturals Collagen Active Joints?
Adults take 1 scoop (5 g), 1 to 2 times per day in water or juice, or as directed by a healthcare practitioner. Use for a minimum of 5 months to see beneficial effects.
What's in each scoop?
Each 5 g scoop contains 5 g of Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine). There are no non-medicinal ingredients - no binders, fillers, artificial colours, flavours or sweeteners.
What is FORTIGEL?
FORTIGEL is a specific bioactive collagen peptide made from hydrolyzed Type I and III collagen (bovine), the sole active ingredient in this product.
What is the licensed use of this product?
This product's Health Canada licence (NPN 80112926) authorizes it to help reduce joint pain associated with osteoarthritis, and as a source of the essential amino acid lysine to help in collagen formation.
Is this the same as Orange Naturals' other collagen products?
No. Collagen Active Joints uses FORTIGEL Type I and III collagen peptides and is licensed for joint pain relief. Orange Naturals' Muscle/Body Balance and Skin Revive collagen products use different bioactive collagen ingredients and are formulated, and separately licensed, for different uses - check each product's own label.
Can I take this if I'm pregnant or breastfeeding?
Consult a healthcare practitioner before use if you are pregnant or breastfeeding.
Are there any side effects?
This product may cause mild gastrointestinal disturbances in some people. Consult a healthcare practitioner if you have concerns.
Is it vegan or vegetarian?
No. The active ingredient is a bovine (cattle-derived) collagen peptide, so this product is not suitable for a vegan or vegetarian diet.
Is Orange Naturals Collagen Active Joints made in Canada?
Yes. It is formulated by Orange Naturals' team of naturopathic doctors and crafted in Canada, licensed by Health Canada under NPN 80112926.
Add Orange Naturals Collagen Active Joints to your daily routine
Get Orange Naturals Collagen Active Joints on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80112926. Helps to reduce joint pain associated with osteoarthritis. Source of the essential amino acid lysine to help in collagen formation. Research summaries on this page concern collagen peptides and their constituent amino acids generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Consult a health care practitioner before use, especially if you are pregnant or breastfeeding. May cause mild gastrointestinal disturbances. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a healthcare practitioner before use of this product if you are pregnant or breastfeeding. May cause mild gastrointestinal disturbances. Do not use if the safety seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps to reduce joint pain associated with osteoarthritis. Source of the essential amino acid lysine to help in collagen formation.
Ingredients
Medicinal Ingredients (per 1 scoop/5 g): Hydrolyzed Collagen - FORTIGEL Bioactive Collagen Peptides, Type I and III (bovine), 5 g. Non-medicinal Ingredients: None.
Directions
Recommended Dose (Adults): Take one scoop (5 g), one to two times per day in water or juice, or as directed by a healthcare practitioner. Recommended Duration of Use: Use for a minimum of 5 months to see beneficial effects.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.