Orange Naturals Baby Probiotics + D3 Drops | 10mL
Visit the Orange Naturals Store Read all reviews on Amazon →| Brand | Orange |
| Serving | 1 serving (5 drops / 0.2 mL) daily for infants age 0 and up |
| Licensed Natural Health Product | NPN 80108938 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 2-IN-1 PROBIOTIC + VITAMIN D3 FOR BABIES: Each 0.2 mL serving (5 drops) provides 1 billion CFU Lacticaseibacillus rhamnosus (GG), 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954), and 10 mcg (400 IU) Vitamin D3 (cholecalciferol) - two daily essentials in one easy dropper bottle.
- HELPS SUPPORT GUT AND IMMUNE HEALTH: Helps support gastrointestinal health and immune function, and helps to build strong bones and teeth.
- HELPS RELIEVE COLIC IN BREASTFED INFANTS: Helps reduce crying episodes and helps improve colic symptom relief in breastfed babies.
- SIMPLE DAILY DROPS FROM DAY ONE: For infants age 0 and up: 1 serving (5 drops) per day, given directly on baby's tongue or on a spoon. Take at least 2-3 hours before or after antibiotics. Shake before use.
- CAUTIONS - READ BEFORE USE: Ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain. Stop use and ask a healthcare practitioner if digestive upset occurs, worsens, or persists beyond 3 days. Made in Canada, licensed under NPN 80108938.
Product Description
Baby Probiotics + D3 Drops - 2 Billion CFU Probiotics & 400 IU Vitamin D3 in One Daily Drop
Orange Naturals Baby Probiotics + D3 Drops pairs 1 billion CFU Lacticaseibacillus rhamnosus (GG) and 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954), together with 10 mcg (400 IU) Vitamin D3 (cholecalciferol), in every 0.2 mL serving (5 drops). Developed by naturopathic doctors and made in Canada, this liquid formula helps support gastrointestinal health and immune function, helps build strong bones and teeth, and helps reduce crying episodes and colic symptoms in breastfed infants, for babies age 0 and up. See the full directions and cautions below. Licensed Natural Health Product NPN 80108938.
Probiotiques Bébé + Gouttes D3 d'Orange Naturals associe 1 milliard UFC de Lacticaseibacillus rhamnosus (GG) et 1 milliard UFC de Bifidobacterium animalis subsp. lactis (DSM 15954), ainsi que 10 mcg (400 UI) de vitamine D3 (cholécalciférol), dans chaque portion de 0,2 mL (5 gouttes). Développé par des médecins naturopathes et fabriqué au Canada, ce format liquide aide à soutenir la santé gastro-intestinale et les fonctions immunitaires, aide à la formation d'une ossature et de dents solides, et aide à réduire les pleurs intenses et les symptômes de coliques chez les nourrissons allaités, pour les bébés dès la naissance. Voir la posologie complète et les mises en garde ci-dessous. NPN 80108938.
A Naturopathic-Developed 2-in-1 Daily Drop for Babies
1 billion CFU Lacticaseibacillus rhamnosus (GG) + 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954) + 400 IU Vitamin D3, developed by naturopathic doctors, for infants age 0 and up
2 Billion CFU Probiotics + 400 IU Vitamin D3 per Serving
Each 0.2 mL serving (5 drops) delivers 1 billion CFU Lacticaseibacillus rhamnosus (GG), 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954), and 10 mcg (400 IU) Vitamin D3 (cholecalciferol).
Developed by Naturopathic Doctors, Made in Canada
Orange Naturals formulas, including this Baby Probiotics + D3 Drops, are developed by naturopathic doctors and made in Canada under NPN 80108938.
Advanced Ingredients, Superior Results
Lacticaseibacillus rhamnosus GG, Bifidobacterium animalis subsp. lactis (BB-12), and vitamin D3 have each been studied for their role in infant gut health, colic, immune development, and bone health. Here is what the wider research explores.
Lacticaseibacillus rhamnosus (GG)
A well-studied probiotic strain (also known by its earlier genus name Lactobacillus rhamnosus GG) studied for gastrointestinal and immune support in infants.
1 billion CFU per serving (5 drops / 0.2 mL)Bifidobacterium animalis subsp. lactis (DSM 15954)
A Bifidobacterium strain (commercially known as BB-12) among the most-documented probiotic strains studied in infants for gut and immune health.
1 billion CFU per serving (5 drops / 0.2 mL)
Vitamin D3 (cholecalciferol)
The standard recommended daily vitamin D dose for infants, supporting the development of strong bones and teeth.
10 mcg (400 IU) per serving (5 drops / 0.2 mL)Orange Naturals Baby Probiotics + D3 Drops: Supplement Facts
Each 1 serving (5 drops / 0.2 mL) contains:
- Lacticaseibacillus rhamnosus (GG)1 billion CFU/milliards UFC
- Bifidobacterium animalis subsp. lactis (DSM 15954)1 billion CFU/milliards UFC
- Vitamin D3 (cholecalciferol)10 mcg/400 IU/UI
Non-Medicinal Ingredients: Non-medicinal ingredients: Dipotassium phosphate, medium chain triglycerides, monopotassium phosphate, silicon dioxide, sodium chloride, sugars (sucrose).
Recommended Use or Purpose: Helps support gastrointestinal health. Helps support immune function. Helps to build strong bones and teeth. Helps reduce crying episodes in breastfed infants with colic. Helps improve colic symptom relief in breastfed babies.
Recommended Dose: Infants (age 0 and up): take 1 serving (5 drops) per day, or as directed by a healthcare practitioner. Take at least 2-3 hours before or after antibiotics. Shake before use. Refrigerate after opening.
Cautions and Warnings: Ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain. Stop use and ask a healthcare practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen, and/or persist beyond 3 days. Do not use if the safety seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque portion (5 gouttes / 0,2 mL) contient :
- Lacticaseibacillus rhamnosus (GG)1 billion CFU/milliards UFC
- Bifidobacterium animalis subsp. lactis (DSM 15954)1 billion CFU/milliards UFC
- Vitamine D3 (cholécalciférol)10 mcg/400 IU/UI
Ingrédients non médicinaux : Ingrédients non médicinaux : Chlorure de sodium, dioxyde de silicium, phosphate de monopotassium, phosphate de dipotassium, sucres (sucrose), triglycérides à chaîne moyenne.
Usage ou fins recommandés : Aide à soutenir la santé gastro-intestinale. Aide à soutenir les fonctions immunitaires. Aide à la formation d'une ossature et de dents solides. Aide à réduire les pleurs intenses chez les nourrissons allaités qui ont des coliques. Aide à soulager les symptômes de coliques chez les nourrissons allaités.
Posologie recommandée : Bébés (âge 0 an et plus) : prendre 1 portion (5 gouttes) par jour, ou selon les indications d'un praticien de la santé. Prendre au moins 2 à 3 heures avant ou après la prise d'antibiotiques. Agiter avant utilisation. Réfrigérer après ouverture.
Mises en garde : Consulter un praticien de la santé avant d'en faire l'usage si votre bébé souffre de fièvre, de vomissements, de diarrhée sanglante ou de douleurs abdominales intenses. Cesser l'utilisation et consulter un praticien de la santé si des symptômes de troubles digestifs (par ex., diarrhée) se manifestent, s'aggravent et/ou persistent au-delà de 3 jours. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.
NPN 80108938
Help support your baby's gut and immune health with Baby Probiotics + D3 Drops
Get Orange Naturals Baby Probiotics + D3 Drops on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Baby Probiotics + D3 Drops
1 billion CFU Lacticaseibacillus rhamnosus (GG) + 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954) + 400 IU Vitamin D3 per serving, developed by naturopathic doctors, for infants age 0 and up - with real cautions you should read before use.
2 Billion CFU Probiotics + 400 IU Vitamin D3
Each 0.2 mL serving (5 drops) delivers two well-studied probiotic strains plus a full 400 IU daily dose of Vitamin D3 (cholecalciferol).
Helps support gut and immune health
Helps support gastrointestinal health and immune function, and helps to build strong bones and teeth.
Helps relieve colic in breastfed babies
Helps reduce crying episodes and helps improve colic symptom relief in breastfed infants.
Real cautions, developed by naturopathic doctors
Ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain. NPN 80108938.
Inside every serving
1 billion CFU Lacticaseibacillus rhamnosus (GG), 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954), and 10 mcg (400 IU) Vitamin D3 (cholecalciferol) in an easy liquid drop - just 1 serving (5 drops) a day for infants age 0 and up.
How to use it
Infants age 0 and up: 1 serving (5 drops) daily
Give 1 serving (5 drops) once a day, directly on baby's tongue or from a spoon.
Time it around antibiotics
If your baby is taking antibiotics, give this product at least 2 to 3 hours before or after the antibiotic dose.
Shake, refrigerate, and read the cautions
Shake before use and refrigerate after opening. Ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain.
Stop and ask a healthcare practitioner if symptoms worsen
Stop use and consult a healthcare practitioner if digestive upset (e.g. diarrhea) occurs, worsens, or persists beyond 3 days.
What the research says about this formula's ingredients
Educational summaries of published research on Lacticaseibacillus rhamnosus GG, Bifidobacterium animalis subsp. lactis (BB-12), and vitamin D3 generally; not product-specific claims. Orange Naturals Baby Probiotics + D3 Drops' own authorized use under NPN 80108938 is that it helps support gastrointestinal health and immune function, helps build strong bones and teeth, and helps reduce crying episodes and colic symptoms in breastfed infants.
A randomized trial found LGG reduced daily crying time in colicky breastfed infants
In 45 colicky breastfed infants given Lacticaseibacillus rhamnosus GG (ATCC 53103) at 5x10^9 CFU per day for 28 days alongside maternal avoidance of cow's milk, median full-force daily crying was reduced from 242 to 104 minutes, and fecal calprotectin decreased significantly compared with placebo.
Human RCT (n=45 infants)A meta-analysis of 4 trials found LGG significantly reduced daily crying time and fecal calprotectin in infants with colic
Pooling 4 randomized controlled trials totaling 168 infants with colic, LGG significantly reduced daily crying time by a mean of 32.59 minutes and reduced fecal calprotectin content compared with placebo or no treatment.
Meta-analysis of randomized controlled trials (n=168 infants)A randomized trial found LGG reduced inflammatory markers alongside crying time in infants with colic
In 58 infants with colic treated with LGG in a randomized, double-blind, placebo-controlled trial, the LGG group showed reduced daily crying duration along with a significant decrease in TNF-alpha and monocyte counts, supporting a possible anti-inflammatory mechanism.
Human RCT (n=58 infants)A systematic review and meta-analysis found probiotics reduced crying in exclusively breastfed infants with colic, but evidence remained insufficient for formula-fed infants
Reviewing 12 trials totaling 1,825 infants, probiotics (mainly Limosilactobacillus reuteri) markedly reduced crying time in exclusively breastfed infants with colic, but the authors concluded there was still insufficient evidence to support probiotic use to manage colic in formula-fed infants or to prevent infant crying generally.
Systematic review and meta-analysis (n=1825 infants, 12 trials)A systematic review found probiotic supplementation significantly shortened crying time in breastfed infants with colic
Reviewing 3 trials totaling 209 breastfed infants with colic, probiotic supplementation significantly and progressively shortened crying time versus simethicone or placebo, reaching a mean difference of about 56 minutes per day by 3 weeks, though evidence in formula-fed infants remained unresolved.
Systematic review and meta-analysis (n=209 infants)A systematic review found probiotics added to infant formula had no significant effect on colic or crying - an honest null finding
Reviewing 10 probiotic studies covering 933 infants given term infant formula, probiotic supplementation did not significantly affect growth, stool frequency or consistency, and did not lower the incidence of colic, crying, spitting up, or vomiting compared with standard formula.
Systematic review (n=933 infants, 10 studies)An ESPGHAN-based update recommends L. reuteri DSM 17938 or Bifidobacterium lactis BB-12 specifically for infant colic in breastfed infants
Reviewing evidence published since 2024 against the 2023 ESPGHAN Special Interest Group recommendations, the update confirms L. reuteri DSM 17938 or Bifidobacterium lactis BB-12 for infant colic in breastfed infants, and LGG for prevention of antibiotic-associated diarrhea, finding no new evidence to justify changing these strain-specific recommendations.
Expert review of clinical guideline evidenceA mechanistic review describes how Bifidobacterium animalis subsp. lactis BB-12 survives gastrointestinal transit and interacts with the host immune system
Reviewing preclinical and clinical data on BB-12, one of the most-documented probiotic strains on the market, the authors describe its gastrointestinal survival mechanisms, its interaction with host epithelial and immune cells, and its relationship with the gut microbiota, concluding its clinical benefits (including for infant colic) likely arise from combined direct and indirect effects rather than a single mechanism.
Mechanistic reviewA narrative review found double-blind randomized trials support Bifidobacterium lactis BB-12 in reducing colic episodes and crying time in breastfed infants
Reviewing pediatric trials of nutraceuticals for gut-brain disorders, the authors report at least two double-blind randomized controlled trials found significant reductions in colic episodes and crying time with L. reuteri DSM 17938 or Bifidobacterium lactis BB-12 (10^9 CFU per day for at least 21 days) in breastfed infants.
Narrative review of randomized controlled trialsA mini-review describes bifidobacteria dominance as a hallmark of a healthy breastfed infant gut, with BB-12 among the best-studied supporting strains
Summarizing infant gut microbiome development from birth through age 3, the authors describe bifidobacteria dominance in early infancy as protective (anti-inflammatory, immunomodulatory, supportive of other beneficial species), and highlight Bifidobacterium animalis subsp. lactis BB-12 as a well-studied strain with demonstrated safety and beneficial effects in infants and children.
Narrative mini-reviewA preclinical study found Bifidobacterium animalis subsp. lactis BB-12 modulated early-life immune cell development in a germ-free mouse model
Administering BB-12 to germ-free mice during early life, researchers found beneficial changes in T-cell subsets in the spleen, thymus and gut intraepithelial lymphocytes, alongside increased production of tryptophan derivatives and short-chain fatty acids, supporting a role for BB-12 in early immune system development.
Preclinical study (germ-free mouse model)A systematic review found Bifidobacterium lactis BB-12-supplemented infant formula reduced gastrointestinal infections and colic/irritability frequency
Updating evidence on probiotic-supplemented infant formula across 20 trials, supplementation with Bifidobacterium lactis Bb12 significantly reduced the number of gastrointestinal infection episodes, and combining Bb12 with Streptococcus thermophilus was associated with a lower frequency of colic or irritability, with no safety concerns for growth or adverse effects.
Systematic review of randomized controlled trialsA pilot trial found daily LGG supplementation in early infancy was well tolerated, though it did not prevent later colic - an honest null finding
In a secondary analysis of 184 infants given a daily dose of 10 billion CFU of LGG or a control for the first 6 months of life, there was no significant difference between groups in the likelihood of a later colic diagnosis, indicating LGG supplementation did not prevent colic in this pilot, though no safety concerns were raised.
Human RCT, secondary analysis (n=184 infants)Asia-Pacific pediatric gastroenterology recommendations support LGG and Bifidobacterium lactis for specific indications, citing a documented history of safe use in infants
Reviewing regional evidence, these recommendations note that specific probiotics with a documented history of safe use in preterm and term infants (including LGG and Bifidobacterium lactis strains) may be considered for indications such as infantile colic and prevention of necrotizing enterocolitis, while cautioning that evidence should still be validated with local trials.
Regional expert consensus recommendationsA randomized trial found infant formula with added LGG was well tolerated and successfully colonized the infant gut microbiome
In a double-blind trial of infants with colic randomized to a partially hydrolyzed formula with or without added LGG, both formulas were well tolerated over the 3-week study, crying/fussing decreased in both groups, and the LGG-containing formula was associated with successful gut colonization and measurable changes in microbiome composition.
Human RCT (n=71 infants)The 2024 Endocrine Society Clinical Practice Guideline recommends empiric vitamin D supplementation for children to prevent rickets
Based on a systematic review of randomized controlled trials, the guideline panel suggests empiric vitamin D supplementation for individuals aged 1 to 18 years, citing its potential to prevent nutritional rickets and lower the risk of respiratory tract infections.
Clinical practice guideline (systematic review-based)A critical appraisal of the 2024 Endocrine Society vitamin D guideline confirms its conclusion that supplementation reduces rickets in children
Summarizing and critically appraising the 2024 Endocrine Society guideline, the authors confirm its central finding that vitamin D supplementation reduces rickets and respiratory tract infections in children, while noting open questions remain about optimal dosing across populations.
Guideline summary and critical appraisalA clinical review describes vitamin D deficiency as a cause of life-threatening hypocalcemia and rickets in infants, preventable through supplementation
Reviewing the literature on pediatric vitamin D deficiency, the authors note it affects 10 to 50% of various pediatric population groups and can cause life-threatening hypocalcemia and crippling rickets in infants and children, describing dietary supplementation as an effective means of prevention and treatment.
Clinical reviewA review confirms breast milk alone provides insufficient vitamin D, supporting the standard 400 IU daily infant supplementation recommendation
The authors note that vitamin D content in human breast milk is low and insufficient to reach the recommended daily intake of 400 IU, and detail current guidelines recommending direct vitamin D supplementation for breastfed infants to prevent hypovitaminosis D.
ReviewA clinician survey found infant-focused clinicians consistently recommend direct vitamin D supplementation to prevent rickets in breastfed infants
Surveying 360 clinicians across family medicine, pediatrics and neonatology, the study found infant-only clinicians were more likely than mixed maternal/infant clinicians to recommend direct vitamin D supplementation to exclusively and partially breastfed infants, reflecting standard practice to prevent rickets.
Clinician survey (n=360)A study of 858 Canadian newborns found low vitamin D status was associated with elevated parathyroid hormone, supporting early supplementation
Measuring vitamin D and parathyroid hormone in 858 healthy term newborns in Montreal, researchers found 20.5% had serum vitamin D below 30 nmol/L, and parathyroid hormone was significantly elevated in infants with the lowest vitamin D levels, supporting vitamin D's functional role in newborn bone health.
Observational study (n=858 newborns)A randomized trial follow-up found higher-dose vitamin D supplementation in infancy was associated with greater bone mineral content at 24 months
Following up 49 children from a trial comparing 1000 IU/day versus 400 IU/day vitamin D supplementation in infancy, the 1000 IU/day group showed significantly greater whole body lean mass, bone mineral content, weight and length at 24 months than the 400 IU/day group.
Randomized controlled trial follow-up (n=49 children)A cross-sectional study found adherence to vitamin D supplementation recommendations was low overall, but higher in children under 2 years
Surveying 710 families at pediatric emergency departments, only 17% of children aged 0 to 16 followed current vitamin D supplementation recommendations overall, though adherence rose to 38% in children under 2 years old, with younger age and pediatrician follow-up associated with better adherence.
Cross-sectional observational study (n=710)A review of preterm infants found early oral vitamin D supplementation, soon after birth, is essential to correct deficiency and support outcomes
Reviewing vitamin D research in preterm infants, a population at increased risk of deficiency, the authors conclude that early enteral vitamin D supplementation achieves higher vitamin D status by one month of age and is linked with improved outcomes, since parenteral nutrition and fortified milk alone cannot provide adequate vitamin D.
Literature reviewFrequently asked questions
What is Orange Naturals Baby Probiotics + D3 Drops and what does it do?
It's a liquid drop formula providing 1 billion CFU Lacticaseibacillus rhamnosus (GG), 1 billion CFU Bifidobacterium animalis subsp. lactis (DSM 15954), and 400 IU Vitamin D3 per serving. It helps support gastrointestinal health and immune function, helps build strong bones and teeth, and helps reduce crying episodes and colic symptoms in breastfed infants.
What age is it for?
The label is formulated for infants age 0 and up. Give 1 serving (5 drops) per day, or as directed by a healthcare practitioner.
How do I give it to my baby?
Shake before use, then give 1 serving (5 drops) directly onto your baby's tongue or on a spoon, once a day.
Can I give it alongside antibiotics?
Take at least 2 to 3 hours before or after antibiotics, per the label directions.
Who should consult a healthcare practitioner before using it?
Ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain, and stop use and ask a healthcare practitioner if digestive upset occurs, worsens, or persists beyond 3 days.
What are the medicinal ingredients?
Each serving (5 drops / 0.2 mL) contains Lacticaseibacillus rhamnosus (GG) 1 billion CFU, Bifidobacterium animalis subsp. lactis (DSM 15954) 1 billion CFU, and Vitamin D3 (cholecalciferol) 10 mcg (400 IU).
How long does one bottle last?
Each 10 mL bottle (250 drops) provides 50 servings - a 50-day supply at the standard 1-serving daily dose.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Help support your baby's gut and immune health with Baby Probiotics + D3 Drops
Get Orange Naturals Baby Probiotics + D3 Drops on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80108938. Helps support gastrointestinal health and immune function. Helps to build strong bones and teeth. Helps reduce crying episodes and helps improve colic symptom relief in breastfed infants. Formulated for infants age 0 and up; ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain. The research summaries on this page concern the individual ingredients generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Ask a healthcare practitioner prior to use if your baby has a fever, vomiting, bloody diarrhea, or severe abdominal pain. Stop use and ask a healthcare practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen, and/or persist beyond 3 days. Do not use if the safety seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps support gastrointestinal health. Helps support immune function. Helps to build strong bones and teeth. Helps reduce crying episodes in breastfed infants with colic. Helps improve colic symptom relief in breastfed babies.
Ingredients
Medicinal Ingredients (each 1 serving / 5 drops / 0.2 mL contains): Lacticaseibacillus rhamnosus (GG), 1 billion CFU. Bifidobacterium animalis subsp. lactis (DSM 15954), 1 billion CFU. Vitamin D3 (cholecalciferol), 10 mcg (400 IU). Non-medicinal Ingredients: Dipotassium phosphate, medium chain triglycerides, monopotassium phosphate, silicon dioxide, sodium chloride, sugars (sucrose).
Directions
Recommended Dose: Infants (age 0 and up): take 1 serving (5 drops) per day, or as directed by a healthcare practitioner. Take at least 2-3 hours before or after antibiotics. Shake before use. Refrigerate after opening.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.