Orange Naturals Astragalus Tincture | 100mL
Visit the Orange Naturals Store| Brand | Orange |
| Serving | 2 mL, 4 times per day |
| Licensed Natural Health Product | NPN 80030900 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada |
About this item
- USED TRADITIONALLY FOR ENERGY: Used in Traditional Chinese Medicine to help support energy levels.
- SUPPORTS A HEALTHY IMMUNE SYSTEM: Used in Herbal Medicine to help maintain a healthy immune system - this product's Health Canada-authorized use.
- TRADITIONALLY USED FOR FREQUENT COLDS: Traditionally used in Chinese Medicine for those individuals who suffer from frequent colds.
- ORGANIC ASTRAGALUS ROOT, 1:4 EXTRACT: Made from organic astragalus root (Astragalus membranaceus), extracted at a 1:4 ratio.
- 250 MG PER ML, FAST-ABSORBING TINCTURE: Each mL delivers 250 mg of Astragalus root extract - take 2 mL, 4 times per day on an empty stomach.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated by Orange Naturals and licensed under NPN 80030900.
Product Description
Astragalus Tincture - Traditional Immune & Energy Support

Orange Naturals Astragalus Tincture delivers 250 mg of organic Astragalus (root, Astragalus membranaceus) per mL, extracted at a 1:4 ratio in a base of grain alcohol and purified water. Used in Herbal Medicine to help maintain a healthy immune system, Astragalus is a long-standing Traditional Chinese Medicine root traditionally used to help support energy levels and for those who suffer from frequent colds. This 100 mL naturopathic tincture is licensed as a Natural Health Product. Licensed Natural Health Product NPN 80030900.
Teinture d'Astragale d'Orange Naturals offre 250 mg d'Astragale biologique (racine, Astragalus membranaceus) par mL, extrait selon un ratio de 1:4 dans une base d'alcool de grain et d'eau purifiée. Utilisée en phytothérapie pour aider à maintenir un système immunitaire sain, l'Astragale est une racine de longue date en médecine traditionnelle chinoise, traditionnellement utilisée pour aider à soutenir les niveaux d'énergie et chez les personnes sujettes aux rhumes fréquents. Cette teinture naturopathique de 100 mL est homologuée comme produit de santé naturel. NPN 80030900.
A Traditional Root, Modern Tincture Format
250 mg Astragalus (root, Astragalus membranaceus), 1:4 extract - fast-absorbing liquid format, 2 mL 4 times daily
250 mg Astragalus per mL
Each mL delivers a full 250 mg dose of organic Astragalus root (Astragalus membranaceus), extracted at a 1:4 ratio - take 2 mL, 4 times per day on an empty stomach.
Fast-Absorbing Tincture Format
As a liquid tincture, Astragalus can begin absorbing in the mouth, offering a fast-acting alternative to capsules or tablets.
Advanced Ingredients, Superior Results
Astragalus membranaceus (Huang Qi) is one of the most widely studied roots in Traditional Chinese Medicine, explored for its role in immune function, cardiovascular health, kidney health and general adaptogenic use. Here is what the wider research explores.
Astragalus (root, Astragalus membranaceus)
A traditional Chinese Medicine root long used as a qi tonic, studied for its role in immune function, cardiovascular health and general resistance to illness.
250 mg per mL, 1:4 extractOrange Naturals Astragalus Tincture: Supplement Facts
Each mL contains:
- Astragalus (root, Astragalus membranaceus), 1:4 extract250 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: 40% grain alcohol, purified water.
Recommended Use or Purpose: Used in Herbal Medicine to help maintain a healthy immune system.
Recommended Dose (Adults): Take 2 mL, 4 times per day, preferably on an empty stomach.
Cautions and Warnings: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding, or if you have an auto-immune disorder. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque mL contient :
- Astragale (racine, Astragalus membranaceus), extrait 1:4250 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Alcool de grain à 40 %, eau purifiée.
Usage ou fins recommandés : Utilisé en phytothérapie pour aider à maintenir un système immunitaire sain.
Posologie recommandée (adultes) : Prendre 2 mL, 4 fois par jour, de préférence à jeun.
Mises en garde : Consulter un praticien de la santé avant d'en faire l'usage si vous êtes enceinte ou allaitez, ou si vous souffrez d'un trouble auto-immun. Garder hors de la portée des enfants.
NPN 80030900
Support your immune system with Astragalus
Get Orange Naturals Astragalus Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy Orange Naturals Astragalus Tincture
250 mg of Astragalus (root, Astragalus membranaceus) per mL, 1:4 extract - a traditional Chinese Medicine root in a fast-absorbing tincture format.
250 mg Astragalus per mL
Each mL delivers a full 250 mg dose of organic Astragalus root (Astragalus membranaceus), extracted at a 1:4 ratio.
Supports a healthy immune system
Used in Herbal Medicine to help maintain a healthy immune system.
Fast-absorbing liquid tincture
Take 2 mL, 4 times per day on an empty stomach - a fast-acting alternative to capsules.
Made in Canada, Health Canada licensed
Formulated by Orange Naturals and licensed as a Natural Health Product. NPN 80030900.
Inside every mL
250 mg Astragalus (root, Astragalus membranaceus), 1:4 extract, per mL - take 2 mL, 4 times per day, preferably on an empty stomach. Non-medicinal ingredients: 40% grain alcohol and purified water.
How to use it
Take 2 mL, 4 times daily on an empty stomach
Adults: take 2 mL, 4 times per day, preferably on an empty stomach.
Use the dropper for accurate dosing
Each 100 mL bottle is designed for precise, drop-by-drop dosing directly into the mouth or in a small amount of water.
Consult a practitioner if pregnant, breastfeeding, or if you have an autoimmune disorder
Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you have an auto-immune disorder.
What the research says about Astragalus
Educational summaries of published research on Astragalus membranaceus generally; not product-specific claims. Orange Naturals Astragalus Tincture's own authorized use under NPN 80030900 is that it is used in Herbal Medicine to help maintain a healthy immune system.
A randomized trial found Astragalus Membranaceus Root restored immune balance in elite rowers after strenuous training
In a double-blind, placebo-controlled study of 18 members of the Polish Rowing Team, 500 mg of Astragalus Membranaceus Root supplementation during a six-week intensive training camp helped sustain natural killer and T regulatory cell levels at baseline and shifted cytokine (IL-2/IL-10) response toward a more favourable balance during recovery from maximal exertion, compared with placebo.
Human RCT (n=18)A randomized trial found Radix Astragali improved symptoms and immune markers as an adjunct therapy in Graves disease
In 80 Graves disease patients randomized to methimazole alone or methimazole plus Radix Astragali, both groups improved thyroid function similarly, but symptoms such as heat intolerance, sweating and palpitations improved more in the Astragalus group, alongside a more pronounced reduction in inflammatory markers IL-1beta and TNF-alpha.
Human RCT (n=80)A randomized trial found a Compound Astragalus Recipe regulated lymphocyte subsets similarly to standard therapy in myasthenia gravis
In 60 myasthenia gravis patients randomized to a Compound Astragalus Recipe or prednisone for 3 months, both treatments produced comparable overall effective rates (80% vs 83.3%) and improved lymphocyte subset distribution and complement levels, with no adverse reactions observed in the Astragalus group versus transient liver-enzyme elevation in 5 prednisone patients.
Human RCT (n=60)A study found Astragalus Membranaceus Injection protected mitochondrial function in a chronic heart failure model
In a pressure-overload chronic heart failure mouse model, Astragalus Membranaceus Injection improved left ventricular ejection fraction, reduced cardiac hypertrophy and fibrosis, and restored mitophagy and mitochondrial homeostasis by inhibiting the AKT/mTOR signaling pathway.
Preclinical studyA study found Astragalus Polyphenols protected heart cells against chemotherapy-induced cardiotoxicity
In cardiomyocyte models of doxorubicin-induced cardiotoxicity, Astragalus Polyphenols reversed reductions in cell viability and mitochondrial membrane potential, lowered reactive oxygen species, and reduced cardiac injury markers ANP and BNP by activating the PI3K/AKT/NRF2 signaling pathway.
Preclinical studyA review describes Astragalus membranaceus among traditional botanicals studied for ischemic heart disease and heart failure
Reviewing botanicals with cardiovascular therapeutic history, Astragalus membranaceus is described as a Chinese 'Qi tonifier' studied for benefit in ischemic heart disease, myocardial infarction, heart failure and anginal pain relief, with its in vitro antioxidant activity proposed as a mechanism for its cardioprotective effect.
ReviewA study found Astragalus polysaccharides trigger immune-activating cell death in melanoma via a gut-microbiota-dependent pathway
In a melanoma model, Astragalus polysaccharides suppressed tumor growth and prolonged survival by inducing immunogenic cell death through the cGAS-STING pathway; depleting the tumor's local microbiota blunted this effect, and administering a specific bacterial byproduct alone was enough to reactivate the pathway.
Preclinical studyA study found Astragalus polysaccharide reprograms tumor-associated macrophages toward an anti-tumor state in liver cancer
In a hepatocellular carcinoma model, Astragalus polysaccharide increased pro-inflammatory, anti-tumor macrophage populations within the tumor microenvironment by suppressing an enzyme (OGT) involved in macrophage polarization, enhancing immune cell infiltration and reducing signs of T-cell exhaustion.
Preclinical studyA review describes how astragalosides activate T cells and regulate inflammation through the NF-kB pathway
Reviewing the immunoregulatory and anti-inflammatory activities of astragalosides (major active components of Astragalus), the review describes their role in T-cell activation, regulation of the effector/regulatory T-cell balance, enhancement of CD45 phosphatase activity, and inhibition of pro-inflammatory cytokines via the NF-kB pathway.
ReviewA study found Astragalus membranaceus enhanced antibody response to a COVID-19 vaccine in mice
Orally administered Astragalus membranaceus water extract, combined with Coriolus versicolor, enhanced the antibody-binding activity of the BNT162b2 mRNA vaccine against ancestral and Delta SARS-CoV-2 spike proteins by 4.3 to 5.8-fold in mice, alongside increased antibody-neutralizing activity, likely via trained immunity of macrophages and dendritic cells.
Preclinical studyA study found Astragalus polysaccharide acted as a persistent immune adjuvant for influenza and SARS-CoV-2 vaccines in mice
As an adjuvant to influenza and recombinant SARS-CoV-2 vaccines in mice, Astragalus polysaccharide increased antibody titers and improved survival and weight recovery after a lethal influenza challenge, with induced antibodies persisting at high levels for at least 20 weeks.
Preclinical studyA study found astragaloside IV reduced inflammation in cigarette-smoke-exposed immune cells via autophagy
In macrophages exposed to cigarette smoke extract, astragaloside IV (a compound prescribed for upper respiratory tract infections) reduced pro-inflammatory cytokine release and rescued cell death by inducing autophagy through the TLR4/NF-kB signaling pathway.
Preclinical studyA Phase I trial found an Astragalus-containing herbal medicine was well tolerated up to 4800 mg per day in cancer patients
In an open-label, dose-escalation Phase I trial of 11 patients with solid cancers, SH003 (containing Astragalus membranaceus, Angelica gigas and Trichosanthes kirilowii) produced only grade 2 or lower adverse events at doses up to 4800 mg/day, with no dose-limiting toxicities observed.
Human Phase I trial (n=11)A Phase I trial found the same Astragalus-containing formula combined safely with a chemotherapy drug in breast and lung cancer patients
In 12 patients with advanced breast or lung cancer, SH003 combined with docetaxel chemotherapy was well tolerated up to 4800 mg/day with no dose-limiting toxicities attributed to SH003; the most common adverse events (neutropenia, mild skin reactions) were primarily linked to docetaxel.
Human Phase I trial (n=12)A randomized trial found an Astragalus and Angelica combination was safe and improved urinary symptoms in men with BPH
In 84 men with benign prostatic hyperplasia symptoms, 12 weeks of SHPro (an Astragalus and Angelica combination) significantly improved prostate symptom scores and erectile function versus control; only mild adverse events (gastrointestinal, skeletal, dermatologic) occurred, none judged related to the product.
Human RCT (n=84)A meta-analysis of 66 trials found Astragalus membranaceus reduced albuminuria and improved kidney markers in diabetic kidney disease
Pooling 4,785 participants across 66 randomized trials, adding Astragalus membranaceus preparations to conventional therapy for diabetic kidney disease reduced albuminuria, proteinuria and serum creatinine more than conventional therapy alone, with a similar adverse-event profile between groups; the authors rated evidence quality as low and called for further high-quality trials.
Meta-analysisA study found astragaloside IV protected kidney cells from diabetes-related damage by regulating iron-dependent cell death
In a diabetic rat model and high-glucose-exposed kidney cells, astragaloside IV (a primary bioactive compound of Astragalus root) improved kidney function and reduced oxidative stress and ferroptosis markers, restoring mitochondrial membrane potential and reducing lipid peroxidation in kidney tubule cells.
Preclinical studyA study found formononetin, an Astragalus compound, improved kidney function in a chronic renal failure model
In an adenine-induced chronic renal failure rat model and human kidney tubule cells, formononetin (one of the main isoflavones isolated from Astragalus membranaceus) reduced serum creatinine and urine protein, improved kidney tissue injury and fibrosis, and inhibited the PI3K/AKT signaling pathway linked to inflammatory cytokine release.
Preclinical studyA randomized trial found an Astragalus-containing formula improved glucose and inflammatory markers in older adults with diabetic sarcopenia
In a 12-week randomized, double-blind, placebo-controlled trial of 90 older adults with diabetic sarcopenia, Shenqi paste (containing Astragalus membranaceus among 8 medicine-food ingredients) significantly improved handgrip strength, muscle mass index and function versus placebo, alongside a significant reduction in fasting blood glucose and C-reactive protein, with no serious adverse events.
Human RCT (n=90)A study found an Astragalus and Rehmannia herb pair improved glucose and lipid metabolism in type 2 diabetic rats
Using network pharmacology and multi-omics analysis, a Rehmannia-Astragalus (Shengdihuang-Huangqi) herb pair significantly improved fasting blood glucose, dyslipidemia and tissue damage in type 2 diabetic rats, with formononetin (an Astragalus compound) identified among the key bioactive contributors acting on insulin resistance and lipid metabolism pathways.
Preclinical studyA study found fermented Astragalus membranaceus outperformed a plain water extract in a diabetic kidney model
Comparing fermented Astragalus membranaceus broth to its plain aqueous extract in diabetic rats, the fermented version produced greater improvements in body weight recovery, fasting blood glucose, kidney function markers and antioxidant capacity, suggesting fermentation improves the bioavailability of Astragalus's active compounds.
Preclinical studyAn overview of 52 systematic reviews found an Astragalus-containing Chinese patent medicine improved outcomes as a cancer adjuvant therapy
Reviewing 52 systematic reviews of Aidi injection (containing Astragalus membranaceus, Panax ginseng and other herbs) used alongside chemotherapy or radiotherapy across lung, liver, colorectal and other cancers, the injection showed additional benefits on survival, tumor response, quality of life and reduction of chemo/radiotherapy side effects - though the authors rated the underlying review quality as generally weak and called for improvement.
Overview of systematic reviewsA review describes Astragalus membranaceus (Huangqi) as a widely used traditional tonic with over 100 identified active compounds
Reviewing the botanical characteristics, phytochemistry and pharmacology of Astragalus membranaceus, the review describes its traditional use as an immune stimulant, tonic, antioxidant, hepatoprotectant, diuretic and antidiabetic, noting more than 100 identified compounds including flavonoids, saponins and polysaccharides.
ReviewA meta-analysis found Astragalus polysaccharide supplementation improved treatment outcomes and immune markers in cancer patients with a high safety profile
Pooling 2,648 participants across 31 randomized trials, adding Astragalus polysaccharide to cancer treatment improved objective response rate and CD3+/CD4+ T-cell counts versus control, with a low incidence of mild adverse reactions such as hand-foot numbness, supporting a favourable safety profile alongside standard cancer therapy.
Meta-analysisFrequently asked questions
What is Orange Naturals Astragalus Tincture and what does it do?
It's a liquid tincture providing 250 mg of Astragalus (root, Astragalus membranaceus), 1:4 extract, per mL. Used in Herbal Medicine to help maintain a healthy immune system.
How do I take it?
Adults take 2 mL, 4 times per day, preferably on an empty stomach.
Who should consult a healthcare practitioner before using it?
Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you have an auto-immune disorder.
What is Astragalus traditionally used for?
In Traditional Chinese Medicine, Astragalus (Huang Qi) is traditionally used to help support energy levels and for those who suffer from frequent colds.
What are the non-medicinal ingredients?
40% grain alcohol and purified water.
How much is in one bottle?
Each bottle contains 100 mL (3.38 fl oz) of tincture.
Is this a Health Canada licensed product?
Yes - it is licensed as a Natural Health Product under NPN 80030900.
Where do I buy it?
Use the orange button on this page - it takes you to the listing on Amazon.ca for secure checkout and fast delivery.
Support your immune system with Astragalus
Get Orange Naturals Astragalus Tincture on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80030900. Used in Herbal Medicine to help maintain a healthy immune system. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you have an auto-immune disorder. The research summaries on this page concern astragalus generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding, or if you have an auto-immune disorder. Keep out of reach of children.
Indications
Recommended Use or Purpose: Used in Herbal Medicine to help maintain a healthy immune system.
Ingredients
Medicinal Ingredients (each mL contains): Astragalus (root, Astragalus membranaceus), 1:4 extract, 250 mg. Non-medicinal Ingredients: 40% grain alcohol, purified water.
Directions
Recommended Dose (Adults): Take 2 mL, 4 times per day, preferably on an empty stomach.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.







