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Health Canada NPN 80021708 400 mg Olive Leaf Extract, 20% Oleuropein Vegan · Non-GMO · Gluten-Free 60 Capsules - 30-Day Supply
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AOR Oleuropein Olive Leaf Extract 400mg - Antioxidant Support | 60 Caps

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$29.45 CAD
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BrandAOR
Serving1 Capsule (400 mg), twice daily
Licensed Natural Health ProductNPN 80021708
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • RICH IN ANTIOXIDANT POLYPHENOLS: AOR Olive Leaf Extract contains numerous flavonoids and antioxidants for the maintenance of good health - its licensed Health Canada use.
  • STANDARDIZED TO 20% OLEUROPEIN: Each 400 mg capsule delivers Olive Leaf (Olea europaea L.) extract standardized to not less than 20% oleuropein, olive leaf's signature antioxidant polyphenol.
  • SUPPORTS DAILY WELLNESS: A traditional Mediterranean botanical studied for its role in cellular antioxidant defense, immune health, and circulatory wellness as part of a healthy daily routine.
  • SIMPLE TWICE-DAILY CAPSULES: Take 1 capsule twice daily, with or without food - 60 vegan capsules provide up to a 30-day supply.
  • VEGAN, NON-GMO, GLUTEN-FREE: Clean-label vegan capsules with no gluten or GMO ingredients, and only two non-medicinal ingredients.
  • A MEDITERRANEAN BOTANICAL TRADITION: Olea europaea leaves have a long history of traditional use around the Mediterranean, now studied for their polyphenol content.
  • PREMIUM CANADIAN QUALITY: Made in Canada by AOR - Advanced Orthomolecular Research - since 1991, to GMP standards. Licensed under Health Canada NPN 80021708.
  • 60 CAPSULES - UP TO A 30-DAY SUPPLY: At 1 capsule twice daily (2 capsules per day), one bottle lasts up to 30 days.

Product Description

Olive Leaf Extract - Standardized Mediterranean Antioxidant

AOR Oleuropein Olive Leaf

Olea europaea (olive) leaves have a long history of traditional use around the Mediterranean. AOR's Olive Leaf Extract is standardized to not less than 20% oleuropein - olive leaf's signature polyphenol - delivering 400 mg of extract in every capsule, taken twice a day. Licensed Natural Health Product; contains numerous flavonoids and antioxidants for the maintenance of good health. Licensed Natural Health Product NPN 80021708.

Les feuilles d'Olea europaea (olivier) ont une longue histoire d'utilisation traditionnelle dans le bassin méditerranéen. L'extrait de feuille d'olive d'AOR est normalisé pour contenir au moins 20 % d'oléuropéine - le polyphénol signature de la feuille d'olive - à raison de 400 mg d'extrait par capsule, prise deux fois par jour. Produit de santé naturel homologué; contient de nombreux flavonoïdes et antioxydants pour le maintien d'une bonne santé. NPN 80021708.

Oleuropein Olive Leaf lifestyle
AOR Oleuropein Olive Leaf
Premium - AOR

Standardized Olive Leaf Extract

60 vegan capsules - a traditional Mediterranean botanical, standardized to 20% oleuropein

Standardized to 20% Oleuropein

Each capsule delivers 400 mg of Olive Leaf (Olea europaea L.) extract standardized to not less than 20% oleuropein, so every capsule provides a consistent, guaranteed level of olive leaf's signature antioxidant polyphenol.

Simple Twice-Daily Capsules

One capsule, twice daily, with or without food - a traditional Mediterranean botanical in a modern, convenient, vegan capsule.

What Olive Leaf Research Explores

Olive leaf's polyphenols, especially oleuropein, are a widely researched area of Mediterranean-diet science - here's what the research explores.

Antioxidant Support

Olive Leaf Extract contains numerous flavonoids and antioxidants for the maintenance of good health - AOR's own licensed Health Canada use.

Cardiovascular Wellness Research

Oleuropein and olive leaf polyphenols are a widely studied area of cardiovascular and blood-pressure research.

Immune Function Research

Olive leaf's polyphenol content is an active area of general immune-health research.

Traditional Mediterranean Botanical

Olea europaea leaves have been used traditionally around the Mediterranean for generations.

AOR Oleuropein Olive Leaf: Supplement Facts

AOR™Oleuropein Olive Leaf
English

Each capsule contains:

  • Olive Leaf (Olea europaea L.) extract standardized to > 20% oleuropein400 mg

Non-Medicinal Ingredients: Microcrystalline cellulose, sodium stearyl fumarate. Capsule: hypromellose.

Recommended Use or Purpose: Olive Leaf extract contains numerous flavonoids and antioxidants for the maintenance of good health. Licensed Natural Health Product, NPN 80021708.

Recommended Dose (Adults 18 years and older): Take 1 capsule twice daily, with or without food, or as directed by a qualified health care practitioner. Do not exceed the daily dose unless instructed by a health care practitioner.

Cautions and Warnings: Do not use if you are pregnant or breastfeeding. Consult a health care practitioner if you have high or low blood pressure, or for use beyond eight weeks. Herbal extracts will naturally vary in colour from one batch to another. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.

Français

Chaque capsule contient :

  • Extrait de feuille d'olivier (Olea europaea L.) normalisé pour contenir > 20 % d'oléuropéine400 mg

Ingrédients non médicinaux : Cellulose microcristalline, stéarylfumarate de sodium. Capsule : hypromellose.

Usage ou fins recommandés : L'extrait de feuille d'olivier contient de nombreux flavonoïdes et antioxydants pour le maintien d'une bonne santé. Produit de santé naturel homologué, NPN 80021708.

Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule deux fois par jour, avec ou sans nourriture, ou selon les recommandations d'un professionnel de la santé qualifié. Ne pas dépasser la dose quotidienne, sauf indication contraire d'un professionnel de la santé.

Mises en garde : Ne pas utiliser si vous êtes enceinte ou si vous allaitez. Consulter un professionnel de la santé si vous souffrez d'hypertension ou d'hypotension, ou pour un usage au-delà de huit semaines. La couleur des extraits de plantes varie naturellement d'un lot à l'autre. Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement fermé dans un endroit frais et sec.

NPN 80021708

Standardized to 20% OleuropeinRich in Antioxidant PolyphenolsVegan · Non-GMO · Gluten-FreeMade in Canada

Add AOR Olive Leaf Extract to your daily routine

Get AOR Olive Leaf Extract on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR Olive Leaf Extract

A standardized, single-ingredient olive leaf extract from a trusted Canadian brand.

Single-ingredient purity

Just Olive Leaf (Olea europaea L.) extract, standardized to 20% oleuropein - no proprietary blends.

Licensed antioxidant use

Contains numerous flavonoids and antioxidants for the maintenance of good health - Health Canada NPN 80021708.

A Mediterranean tradition

Olea europaea leaves have a long history of traditional use across the Mediterranean region.

Premium Canadian brand

AOR - Advanced Orthomolecular Research, since 1991. NPN 80021708.

How to use it

Take 1 capsule, twice daily

Adults 18 years and older: take 1 capsule twice daily, with or without food, or as directed by a qualified health care practitioner.

Morning and evening

With or without food - two consistent times a day works best, for example morning and evening.

Check in before extended use

Consult a health care practitioner if you have high or low blood pressure, or before using beyond eight weeks.

What the research says about olive leaf and oleuropein

Peer-reviewed studies on olive leaf extract and its key polyphenol, oleuropein - shared for education, not as claims about this finished product. AOR Oleuropein Olive Leaf Extract's authorized use under NPN 80021708 is: olive leaf extract contains numerous flavonoids and antioxidants for the maintenance of good health.

Cardiovascular & Blood Pressure Research

Large multicenter trial in treated hypertension

In a 621-participant, double-blind, placebo-controlled multicenter trial, oral olive leaf extract was evaluated over 12 weeks for its effect on 24-hour systolic and diastolic blood pressure in patients being treated for hypertension.

Human RCT
Lamti et al., Journal of Hypertension (2025)
Cardiovascular & Blood Pressure Research

Olive leaf extract plus potassium in mild hypertension

In a double-blind, placebo-controlled trial, 70 adults with untreated mild-to-moderate hypertension took a combination of olive leaf extract and potassium, evaluated for effects on blood pressure and cardiometabolic markers.

Human RCT
Fladerer-Grollitsch et al., Phytomedicine (2026)
Cardiovascular & Blood Pressure Research

Meta-analysis across pre-hypertensive and hypertensive adults

Pooling randomized trials of Olea europaea leaf extract in adults with pre-hypertension or hypertension, this systematic review and meta-analysis evaluated the overall impact on blood pressure readings.

Meta-analysis
Lachovicz et al., Phytotherapy Research (2025)
Immune Function Research

Gene-expression signals in a human supplementation trial

In a double-blind, placebo-controlled human trial, olive leaf extract supplementation shifted gene-expression profiles in peripheral blood immune cells, an early step toward understanding its biological mode of action.

Human RCT
Boss et al., International Journal of Molecular Sciences (2016)
Immune Function Research

Calming an allergic-inflammation trigger

Laboratory research found olive leaf extract reduced activation of mast cells, the immune cells at the center of allergic inflammation, suggesting a possible mechanism behind traditional interest in olive leaf for immune balance.

Laboratory study
Somma et al., Biomedicine & Pharmacotherapy (2024)
Immune Function Research

Immune and gut-microbiota effects in diet-induced obesity

In mice with diet-induced obesity, a chemically characterized olive leaf extract improved vascular function and favorably shifted gut microbiota, alongside immunomodulatory effects linked to its polyphenol content.

Animal study
Vezza et al., Pharmacological Research (2019)
Antioxidant Mechanisms

Mapping oleuropein's antioxidant pathways

A comprehensive 2026 review traced oleuropein's antioxidant and anti-inflammatory activity to specific molecular pathways, positioning it as one of the most-studied polyphenols found in olive leaf extract.

Review
Yu et al., Molecular Biology Reports (2026)
Antioxidant Mechanisms

Supporting cellular energy production

In cell culture, oleuropein and hydroxytyrosol - olive leaf's two signature polyphenols - enhanced mitochondrial function and the cell's own antioxidant machinery through estrogen-receptor-linked signaling.

Mechanism
Leri et al., Food & Function (2026)
Antioxidant Mechanisms

Antioxidant, anti-inflammatory signaling in skin cells

In human skin-cell models, olive leaf extract calmed inflammatory signaling and reduced markers of oxidative stress via the AKT/ERK and SREBP-1/PPAR-gamma pathways.

Laboratory study
Kim et al., Current Issues in Molecular Biology (2026)
Blood Sugar & Metabolic Research

Improved insulin sensitivity in a crossover trial

In a randomized, placebo-controlled crossover trial, 46 overweight middle-aged men taking daily olive leaf polyphenols (51.1 mg oleuropein, 9.7 mg hydroxytyrosol) showed a 15% improvement in insulin sensitivity and better pancreatic beta-cell responsiveness versus placebo.

Human RCT
de Bock et al., PLoS ONE (2013)
Blood Sugar & Metabolic Research

Added to a weight-loss diet in obese women

In an 8-week randomized trial, adding olive leaf extract to a calorie-restricted diet was evaluated for its effect on body weight, fat mass, and glycemic indices in women with obesity, versus a standard weight-loss diet alone.

Human RCT
Haidari et al., Clinical Nutrition Research (2021)
Blood Sugar & Metabolic Research

Insulin resistance and blood pressure together in aging rats

In aged rats, an olive leaf extract blend attenuated age-related insulin resistance, high blood pressure, and muscle loss (sarcopenia) together, consistent with the ingredient's broader cardiometabolic research profile.

Animal study
González-Hedström et al., Antioxidants (2021)
Safety & Tolerability Research

A laboratory basis for the blood-pressure caution

Laboratory research on a related wild olive leaf extract found it altered intestinal absorption of two antihypertensive drugs (propranolol and diltiazem) in a human intestinal-cell model - a plausible mechanism supporting the product label's caution to consult a health care practitioner if you have high or low blood pressure.

Laboratory study
Mmopele et al., Planta Medica (2018)
Safety & Tolerability Research

A pilot safety and efficacy trial in type 2 diabetes

A pilot randomized, placebo-controlled trial evaluated both the safety and glycaemic-control effects of olive leaf extract in adults with type 2 diabetes, part of the broader human safety record for the ingredient.

Pilot clinical trial
Leach et al., Complementary Therapies in Clinical Practice (2025)
Safety & Tolerability Research

Liver-enzyme monitoring alongside an antioxidant benefit

In a randomized, placebo-controlled trial in women with obesity, olive leaf extract lowered a marker of oxidative stress with no adverse change in liver enzymes over 8 weeks, part of the ingredient's monitored human safety profile.

Human RCT
Haidari et al., Nutrition, Metabolism and Cardiovascular Diseases (2025)
Comparative Polyphenol Research

Comparing extraction methods for antioxidant yield

This study compared pressurized-liquid and ultrasound-assisted extraction using green solvents, evaluating which method best preserved olive leaf's antioxidant and blood-sugar-related enzyme-inhibiting compounds.

Laboratory analysis
Huamán-Castilla et al., Antioxidants (2024)
Comparative Polyphenol Research

Comparing delivery formats for stability

Comparing three liposomal carrier systems, this study measured which formulation best preserved olive leaf extract's antioxidant capacity and physical stability over time.

Laboratory analysis
Baljak et al., Pharmaceuticals (2025)
Comparative Polyphenol Research

Olive leaf compared alongside other antioxidant botanicals

Comparing olive leaf, bay laurel, and rosemary leaf powders, this study measured antioxidant synergy in vitro, then confirmed benefits to blood oxidative status in a live-animal feeding trial.

Animal study
D'Alessandro et al., Animals (2025)
Olive Leaf Phytochemistry

Mapping 300+ compounds across the olive plant

This 2026 review catalogued more than 300 distinct metabolites identified across olive leaves, fruit, oil, and other plant parts, organizing them into 15 chemical classes to guide future research.

Review
Mohamaden et al., RSC Advances (2026)
Olive Leaf Phytochemistry

Identifying a new olive-leaf compound

Researchers isolated and chemically synthesized 2'-hydroxyoleacein, a previously uncharacterized compound related to oleuropein found in olive leaves, and evaluated its anti-inflammatory activity.

Laboratory analysis
Koutra et al., Phytochemistry (2026)
Olive Leaf Phytochemistry

49 phytochemicals across 12 olive cultivars

Analyzing leaf extracts from 12 different olive cultivars by HPLC and mass spectrometry, researchers identified 49 distinct phytochemicals, mapping how the phenolic profile - including oleuropein - varies by variety and season.

Laboratory analysis
Kabbash et al., Scientific Reports (2023)
Dosing & Bioavailability

Tracking absorption after a real dose

In nine healthy volunteers given a single dose of olive leaf extract, researchers measured how much oleuropein and hydroxytyrosol was actually absorbed and how the body metabolized them, mapping the extract's real-world bioavailability.

Human study
de Bock et al., Molecular Nutrition & Food Research (2013)
Dosing & Bioavailability

What gut bacteria do with unabsorbed polyphenols

Using a human fecal-microbiota model, this study traced how gut bacteria further metabolize oleuropein and related olive polyphenols that pass through the small intestine, a step in understanding their full bioavailability.

Laboratory analysis
Mosele et al., Molecular Nutrition & Food Research (2014)
Dosing & Bioavailability

Bioavailability of olive leaf's sister compound

This human trial measured oral bioavailability of hydroxytyrosol - the metabolite oleuropein converts into in the body - from food-supplement sources, addressing the low, variable absorption that has long challenged olive-polyphenol research.

Human RCT
Bender et al., Nutrients (2023)

Frequently asked questions

What is AOR Olive Leaf Extract used for?

AOR Olive Leaf Extract is a licensed Natural Health Product (NPN 80021708). Its recommended use is: olive leaf extract contains numerous flavonoids and antioxidants for the maintenance of good health.

How do I take it?

Adults 18 years and older: take 1 capsule twice daily, with or without food, or as directed by a qualified health care practitioner. Do not exceed the daily dose unless instructed by a health care practitioner.

What is oleuropein, and how much is in each capsule?

Oleuropein is olive leaf's signature antioxidant polyphenol. Each capsule provides 400 mg of Olive Leaf (Olea europaea L.) extract standardized to contain not less than 20% oleuropein.

Who should check with a health care practitioner before using it?

Consult a health care practitioner before use if you have high or low blood pressure, or if you plan to use it beyond eight weeks. Do not use if you are pregnant or breastfeeding.

Does olive leaf extract interact with blood pressure medication?

Olive leaf extract itself has been studied for mild blood-pressure-lowering activity, which is why the label advises consulting a health care practitioner if you have high or low blood pressure before use. If you take blood-pressure medication, mention this supplement to your health care practitioner before starting it.

Is it vegan and gluten-free?

Yes - the capsules are vegan, non-GMO and gluten-free, with only two non-medicinal ingredients: microcrystalline cellulose and sodium stearyl fumarate, in a hypromellose capsule.

How long does one bottle last?

60 capsules is up to a 30-day supply at 1 capsule twice daily (2 capsules per day).

Is olive leaf extract the same as olive oil?

No. This product is made from Olea europaea LEAF extract, standardized for its oleuropein polyphenol content - a different part of the olive tree, and a different nutrient profile, than olive oil, which comes from the fruit.

Standardized to 20% OleuropeinRich in Antioxidant PolyphenolsVegan · Non-GMO · Gluten-FreeMade in Canada

Add AOR Olive Leaf Extract to your daily routine

Get AOR Olive Leaf Extract on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80021708. Olive Leaf extract contains numerous flavonoids and antioxidants for the maintenance of good health. The research summaries below concern olive leaf and oleuropein generally and are educational; they are not claims about this finished product beyond its own licensed use. Read and follow the label. Consult a health care practitioner before use if you have high or low blood pressure, or for use beyond eight weeks. Do not use if you are pregnant or breastfeeding. AOR is the manufacturer; sold by Canadian Health & Care on Amazon.ca. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you are pregnant or breastfeeding. Consult a health care practitioner if you have high or low blood pressure, or for use beyond eight weeks. Herbal extracts will naturally vary in colour from one batch to another. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place.

Indications

Recommended Use or Purpose: Olive Leaf extract contains numerous flavonoids and antioxidants for the maintenance of good health. Licensed Natural Health Product, NPN 80021708.

Ingredients

Medicinal Ingredient (per capsule): Olive Leaf (Olea europaea L.) leaf extract, standardized to contain not less than 20% oleuropein - 400 mg. Non-medicinal ingredients: microcrystalline cellulose, sodium stearyl fumarate. Capsule: hypromellose.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule twice daily, with or without food, or as directed by a qualified health care practitioner. Do not exceed the daily dose unless instructed by a health care practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.