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Health Canada NPN 80002697 600 mg L-arginine HCl per capsule Vegan · Non-GMO · Gluten-free · Dairy-free Made in Canada · GMP facility
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AOR Arginine 600mg - L-Arginine for Circulation | 180 Caps

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$34.70 CAD
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BrandAOR
Serving600 mg (1 capsule)
Licensed Natural Health ProductNPN 80002697
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORTS NITRIC OXIDE PRODUCTION: L-Arginine is the body's main dietary precursor for nitric oxide (NO), a signaling molecule that helps blood vessels open wider to support healthy blood flow and circulation.
  • CIRCULATORY & CARDIOVASCULAR WELLNESS: By supporting nitric oxide synthesis, L-arginine helps support healthy blood flow and general cardiovascular wellness as part of a balanced diet.
  • MUSCLE TONE & EXERCISE PERFORMANCE: L-Arginine supports muscle tone and exercise performance, helping active routines through its role in circulation and amino acid metabolism.
  • SKIN ELASTICITY SUPPORT: As a building block for connective tissue, L-arginine supports skin elasticity alongside a healthy diet and lifestyle.
  • BALANCED NUTRITION FOR LOWER-MEAT DIETS: L-Arginine helps round out balanced nutrition, especially for those following a lower-meat diet where dietary arginine intake may be reduced.
  • 600 MG PER VEGAN CAPSULE: Each vegan capsule delivers 600 mg of L-arginine HCl - 180 capsules per bottle, up to a two-month supply at the labeled dose.
  • DAIRY-FREE, GLUTEN-FREE, NON-GMO, VEGAN: A clean-label formula free of dairy, gluten and animal ingredients, with no undeclared fillers.
  • PREMIUM CANADIAN QUALITY: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80002697.

Product description

AOR Arginine

AOR Arginine

A closer look at AOR Arginine 600 mg - an essential amino acid for circulation and vitality, made in Canada. Licensed Natural Health Product NPN 80002697.

Arginine lifestyle
AOR Arginine
Premium Quality

AOR Arginine

The main dietary precursor for nitric oxide - support for circulation, muscle performance and vitality.

Nitric Oxide Support

L-Arginine is the body's main precursor for nitric oxide, a molecule that helps blood vessels open wider for healthy blood flow.

Circulatory Wellness

Supports healthy circulation and general cardiovascular wellness as part of a balanced diet and active lifestyle.

Amino Acid for Circulatory Wellness

Arginine is a conditionally essential amino acid and the body's main precursor for nitric oxide (NO) - a molecule that helps blood vessels open wider for healthy blood flow and circulation.

Circulatory Health

Helps support healthy vascular function and blood flow.

Nitric Oxide Support

A direct dietary precursor for the body's nitric oxide production.

Muscle Performance

Supports muscle tone and exercise performance as part of an active routine.

Skin & Daily Vitality

Supports skin elasticity and balanced nutrition for everyday vitality.

AOR Arginine: Supplement Facts

AOR™Arginine
English

Each capsule contains:

  • L-Arginine HCl600 mg

Non-Medicinal Ingredients: Sodium stearyl fumarate, microcrystalline cellulose.

Recommended Purpose: A source of L-arginine, a conditionally essential amino acid and the body's main dietary precursor for the synthesis of nitric oxide (NO), a molecule that helps blood vessels open wider for healthy blood flow and circulation. Helps support muscle tone and exercise performance, skin elasticity, and balanced nutrition, especially for those following a lower-meat diet.

Recommended Dose (Adults 18 years and older): Take 3 capsules, one to three times daily, on an empty stomach, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules. Swallow capsules whole.

Cautions and Warnings: Do not use if you have had a myocardial infarction (heart attack). Consult a health care practitioner prior to use if you have asthma, if you are pregnant or breastfeeding, or if you are taking cardiovascular medications, potassium-increasing drugs, or sildenafil. Do not crush, mix or blend capsules; swallow capsules whole. Consult a health care practitioner if symptoms persist or worsen. Keep out of reach of children. Store in a cool, dry place. Sealed for your protection - do not use if the seal is broken.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Chaque capsule contient :

  • Chlorhydrate de L-arginine600 mg

Ingrédients non médicinaux : Stéarylfumarate de sodium, cellulose microcristalline.

Usage recommandé : Une source de L-arginine, un acide aminé conditionnellement essentiel et le principal précurseur alimentaire du corps pour la synthèse de l'oxyde nitrique (NO), une molécule qui aide les vaisseaux sanguins à s'ouvrir davantage pour une circulation sanguine saine. Aide à soutenir le tonus musculaire et la performance à l'exercice, l'élasticité de la peau, et une nutrition équilibrée, surtout pour ceux suivant un régime pauvre en viande.

Dose recommandée (adultes de 18 ans et plus) : Prendre 3 capsules, une à trois fois par jour, à jeun, ou selon les directives d'un praticien de soins de santé qualifié. Ne pas écraser, mélanger ou broyer les capsules. Avaler les capsules entières.

Mises en garde et précautions : Ne pas utiliser si vous avez subi une crise cardiaque (infarctus du myocarde). Consultez un praticien de soins de santé avant l'utilisation si vous avez de l'asthme, si vous êtes enceinte ou si vous allaitez, ou si vous prenez des médicaments pour une maladie cardiovasculaire, des médicaments augmentant le potassium, ou du sildénafil. Ne pas écraser, mélanger ou broyer les capsules; avaler les capsules entières. Consultez un praticien de soins de santé si les symptômes persistent ou s'aggravent. Garder hors de la portée des enfants. Conserver dans un endroit frais et sec. Scellé pour votre protection - ne pas utiliser si le sceau est brisé.

NPN 80002697

Pure L-arginine HCl, 600 mg180 vegan capsules · up to a 2-month supplyVegan · Non-GMO · Gluten-free · Dairy-freeMade in Canada

Support circulation, nitric oxide production & vitality the easy way

Get AOR Arginine on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why people choose Arginine

One essential amino acid - four ways it supports your body.

Circulatory Support

Helps support healthy blood flow and vascular function by fueling the body's nitric oxide production.

Nitric Oxide Production

L-Arginine is the direct dietary precursor the body uses to synthesize nitric oxide, a key vascular signaling molecule.

Muscle & Exercise Performance

Supports muscle tone and exercise performance as part of an active routine.

Skin Elasticity & Vitality

Supports skin elasticity and balanced nutrition, especially for those following a lower-meat diet.

How to use

Take

Adults 18 years and older: take 3 capsules, one to three times daily, on an empty stomach, or as directed by a health care practitioner.

Swallow whole

Do not crush, mix or blend capsules - swallow capsules whole with water.

Time it right

Take on an empty stomach for consistent absorption; if taking more than once daily, space doses evenly through the day.

Stay consistent

Use daily as part of your routine; one 180-capsule bottle lasts up to a two-month supply at the labeled dose.

What the research says about L-arginine

Peer-reviewed studies and reviews on the amino acid L-arginine - shared for education, not as claims about this finished product. AOR Arginine's claims are the statements authorized under its Natural Health Product licence, NPN 80002697.

Nitric Oxide Synthesis

Arginine, the NO substrate

A review explains that L-arginine is the body's essential dietary substrate for synthesizing nitric oxide (NO), a signaling molecule that helps widen blood vessels and increase blood flow to tissues including skeletal muscle.

Review
Wu, Advances in Experimental Medicine and Biology (2021)
Nitric Oxide Synthesis

How the body makes nitric oxide

This review describes the nitric oxide synthase enzymes that catalyze the conversion of L-arginine into nitric oxide and L-citrulline, the core biochemical pathway behind arginine's vascular role.

Review
Stuehr, Journal of Nutrition (2004)
Nitric Oxide Synthesis

A Nobel Prize-winning discovery

A historical review traces the 1998 Nobel Prize in Physiology or Medicine, awarded to Furchgott, Ignarro and Murad for discovering nitric oxide's role as a signaling molecule in the cardiovascular system - the same pathway for which L-arginine is the precursor.

Historical review
Lancaster, Biochemical Pharmacology (2020)
Vascular & Endothelial Function

Arginine and vessel-lining function

A meta-analysis of randomized trials found that oral L-arginine supplementation increased fasting flow-mediated dilation (a measure of endothelial function), with the largest improvements seen in people whose baseline vascular function was low.

Meta-analysis
Bai et al., American Journal of Clinical Nutrition (2008)
Vascular & Endothelial Function

Nitric oxide synthase and vascular tone

A review in a leading cardiology journal describes how the nitric oxide synthase enzymes rely on L-arginine as their substrate to regulate the tone of blood vessels throughout the body.

Review
Forstermann & Sessa, European Heart Journal (2011)
Vascular & Endothelial Function

Testing endothelial reactivity with arginine

A review discusses how L-arginine-based reactivity testing has been used by researchers to help characterize endothelial (vessel-lining) function, including in the cerebral circulation.

Review
Pretnar-Oblak, BioMed Research International (2014)
Blood Pressure

Meta-analysis: arginine and blood pressure

A meta-analysis of 11 randomized, placebo-controlled trials found that oral L-arginine supplementation (4-24 g per day) significantly lowered both systolic (-5.4 mmHg) and diastolic (-2.7 mmHg) blood pressure compared with placebo.

Meta-analysis
Dong et al., American Heart Journal (2011)
Blood Pressure

An updated dose-response analysis

A 2022 systematic review and dose-response meta-analysis of 22 randomized trials confirmed reductions in systolic and diastolic blood pressure with oral L-arginine, identifying an effective dose of about 4 g per day or more for systolic blood pressure.

Meta-analysis
Shiraseb et al., Advances in Nutrition (2022)
Blood Pressure

The arginine-nitric oxide pathway in hypertension

A review describes how a reduced or impaired L-arginine-to-nitric-oxide pathway is implicated in the pathophysiology of difficult-to-control high blood pressure.

Review
Rajapakse et al., Clinical Science (2019)
Exercise & Muscle Performance

Food-based NO-pathway nutrients and endurance

A systematic review and meta-analysis examined whether dietary sources of nitrate, polyphenols, L-arginine and L-citrulline (compounds that support nitric oxide availability) can enhance endurance exercise performance.

Meta-analysis
d'Unienville et al., Journal of the International Society of Sports Nutrition (2021)
Exercise & Muscle Performance

Single-dose arginine and blood flow

A randomized crossover trial gave physically active men either L-arginine or a placebo before resistance exercise; the increase in blood flow and vascular response seen after exercise was attributed to the exercise itself rather than to the added arginine.

Human RCT
Fahs et al., Medicine & Science in Sports & Exercise (2009)
Exercise & Muscle Performance

Raising plasma arginine around training

A week of arginine-alpha-ketoglutarate supplementation raised plasma L-arginine and nitric-oxide-metabolite levels around resistance exercise, though the study attributed the blood-flow response itself mainly to the exercise bout.

Human RCT
Willoughby et al., International Journal of Sport Nutrition and Exercise Metabolism (2011)
Wound Healing

Meta-analysis on amino acids and wound repair

A systematic review and meta-analysis evaluated the effect of arginine and glutamine supplementation on wound-healing outcomes across clinical studies.

Meta-analysis
Arribas-Lopez et al., Nutrients (2021)
Wound Healing

How arginine supports tissue repair

A review describes arginine's roles in protein synthesis, nitric-oxide-mediated cell signaling, and its conversion to polyamines that support cell proliferation - mechanisms relevant to wound healing.

Review
Stechmiller et al., Nutrition in Clinical Practice (2005)
Wound Healing

Arginine and glutamine for pressure ulcers

A systematic review examined enteral arginine and glutamine supplementation for supporting collagen synthesis and tissue repair in the management of pressure ulcers.

Systematic review
Torsy et al., Wound Repair and Regeneration (2025)
Immune Function

A foundational review on arginine and immunity

An early review outlined arginine's role in supporting immune-cell function, part of the foundational research linking this amino acid to the body's immune defenses.

Review
Barbul, Nutrition (1990)
Immune Function

A regulatory node for immune responses

A review describes how, over the course of immune-system evolution, arginine availability has become a key node regulating the activity of immune cells.

Review
Marti i Lindez & Reith, Cellular and Molecular Life Sciences (2021)
Immune Function

Arginine and post-surgical immune markers

A meta-analysis of clinical trials examined arginine supplementation in relation to immune-function markers and postoperative recovery in surgical patients.

Meta-analysis
Ouyang et al., BMC Cancer (2024)
Growth Hormone Research

The classic arginine infusion test

A landmark clinical study established the arginine-infusion test as a way to stimulate and measure growth-hormone secretion, a tool still referenced in endocrine research today.

Human RCT
Baker et al., Lancet (1970)
Growth Hormone Research

Confirming arginine's effect on growth hormone

Another early clinical study documented the rise in circulating growth hormone following intravenous arginine infusion, helping establish this amino acid's role in growth-hormone physiology.

Human study
Hembree et al., Lancet (1969)
Growth Hormone Research

Arginine stimulation testing today

A modern study analyzed growth-hormone responses during arginine (plus clonidine) stimulation testing in children being evaluated for short stature, correlating results with metabolic parameters.

Clinical study
Sodero et al., Growth Hormone & IGF Research (2022)
Safety & Pharmacokinetics

Reviewing arginine's safety in adults

A review of the safety and effectiveness literature identified an observed safe level of oral arginine intake around 20 g per day in adults, with higher doses tested short-term without serious adverse effects.

Review
McNeal et al., Journal of Nutrition (2016)
Safety & Pharmacokinetics

Pharmacokinetics across species

Preclinical studies in pigs, rats and sheep examined the pharmacokinetics and safety of oral and intravenous arginine supplementation, informing the dosing science behind later human research.

Animal study
Wu et al., Journal of Nutrition (2007)
Safety & Pharmacokinetics

Why medical supervision matters after a heart attack

A meta-analysis of trials in patients with a recent acute myocardial infarction found that oral L-arginine supplementation did not significantly change clinical outcomes in that setting - part of why cardiac patients are directed to use arginine only under medical supervision.

Meta-analysis
Sun et al., Clinical Cardiology (2009)

Frequently asked questions

What is L-arginine and what does it do?

L-Arginine is a conditionally essential amino acid and the body's main precursor for nitric oxide (NO), a molecule that helps blood vessels open wider to support healthy blood flow, circulation and muscle performance.

How do I take it?

Adults 18 years and older take 3 capsules, one to three times daily, on an empty stomach, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules - swallow whole.

How long does one bottle last?

Each bottle contains 180 vegan capsules - up to a two-month supply, depending on how many times per day you take it.

What's in it besides L-arginine?

Each capsule contains 600 mg of L-arginine HCl, with sodium stearyl fumarate and microcrystalline cellulose as non-medicinal ingredients, in a hypromellose (vegan) capsule.

Is it vegan and allergen-friendly?

Yes - it is vegan, non-GMO, gluten-free and dairy-free, with no animal-derived ingredients.

Who should not use it?

Do not use if you have had a myocardial infarction (heart attack). Consult a health care practitioner prior to use if you have asthma, are pregnant or breastfeeding, or are taking cardiovascular medications, potassium-increasing drugs, or sildenafil.

Is it made in Canada?

Yes. It is manufactured in Canada in a GMP-compliant facility by AOR and licensed by Health Canada under NPN 80002697.

Where do I buy it?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.

Pure L-arginine HCl, 600 mg180 vegan capsules · up to a 2-month supplyVegan · Non-GMO · Gluten-free · Dairy-freeMade in Canada

Support circulation, nitric oxide production & vitality the easy way

Get AOR Arginine on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80002697. L-Arginine is a conditionally essential amino acid and the body's main dietary precursor for nitric oxide production, supporting healthy circulation, muscle performance and skin elasticity. The research summaries below concern the amino acid L-arginine and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner prior to use if you have had a heart attack, have asthma, are pregnant or breastfeeding, or are taking cardiovascular medications, potassium-increasing drugs, or sildenafil. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you have had a myocardial infarction (heart attack). Consult a health care practitioner prior to use if you have asthma, if you are pregnant or breastfeeding, or if you are taking cardiovascular medications, potassium-increasing drugs, or sildenafil. Do not crush, mix or blend capsules; swallow capsules whole. Consult a health care practitioner if symptoms persist or worsen. Keep out of reach of children. Store in a cool, dry place. Sealed for your protection - do not use if the seal is broken.

Indications

Recommended Purpose: A source of L-arginine, a conditionally essential amino acid and the body's main dietary precursor for the synthesis of nitric oxide (NO), a molecule that helps blood vessels open wider for healthy blood flow and circulation. Helps support muscle tone and exercise performance, skin elasticity, and balanced nutrition, especially for those following a lower-meat diet.

Ingredients

Medicinal Ingredients (per capsule): L-Arginine HCl 600 mg. Non-medicinal ingredients: sodium stearyl fumarate, microcrystalline cellulose. Capsule: hypromellose (vegan). Dairy-free, gluten-free, non-GMO, vegan - contains no wheat, gluten, nuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or animal byproduct. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and older): Take 3 capsules, one to three times daily, on an empty stomach, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules. Swallow capsules whole.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.