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Health Canada NPN 80005752 Pure myo-Inositol, 500 mg per capsule Vegan · Non-GMO · Gluten-Free Made in Canada · GMP facility
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AOR Inositol 500mg - Myo-Inositol for Mental Well-Being | 90-180 Caps

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$28.25 CAD
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BrandAOR
Serving1 Capsule
Licensed Natural Health ProductNPN 80005752
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORT MENTAL WELL-BEING: AOR Inositol Caps 500mg can support a sense of balance and overall well-being - myo-inositol plays a role in maintaining healthy brain function, helping you feel calm and positive with regular use.
  • SUPPORT COGNITIVE HEALTH: Nourish your brain with our myo-inositol supplement, carefully formulated to help maintain focus and mental sharpness so you can stay clear-headed throughout the day.
  • PROMOTE MENTAL HARMONY: AOR's inositol capsules offer a natural way to help maintain emotional steadiness by assisting in the regulation of brain-signaling functions.
  • SUPPORT WOMEN'S HORMONAL BALANCE: Myo-inositol is studied for its role in supporting healthy hormonal balance, making these capsules a simple daily addition to a women's wellness routine.
  • SIMPLE AND EFFECTIVE: Each vegan capsule provides 500 mg of pure myo-inositol - a practical, single-ingredient approach to supporting cognitive and mental wellness.
  • CLEAN, ALLERGEN-FRIENDLY FORMULA: Vegan, Non-GMO and Gluten-Free, with no non-medicinal ingredients beyond the hypromellose capsule shell.
  • TRUSTED CANADIAN QUALITY: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80005752 - available in a 90-capsule (90-day) or 180-capsule (6-month) supply.

Product description

AOR Inositol Caps - Myo-Inositol for Mental Well-Being & Hormonal Balance

AOR Inositol

A closer look at AOR Inositol Caps 500mg - pure myo-inositol, a naturally occurring cellular signaling compound studied for its role in supporting mental well-being, cognitive function, hormonal balance and metabolic wellness. Licensed Natural Health Product NPN 80005752.

Inositol lifestyle
AOR Inositol
90-180 Capsules · Vegan · Non-GMO

Why AOR Inositol Caps

One real ingredient, 500 mg per capsule - a simple, single-ingredient way to support brain, hormonal and metabolic wellness.

Backed by science

Myo-inositol is a naturally occurring second-messenger precursor studied for its role in mood, cognitive, hormonal and metabolic health - AOR Inositol Caps deliver a clinically relevant 500 mg per capsule.

The AOR difference

Each vegan capsule delivers 500 mg of pure myo-inositol with no non-medicinal ingredients beyond the hypromellose capsule shell - available in a 90-capsule or 180-capsule bottle to match your routine.

What AOR Inositol Caps Supports

Four ways myo-inositol supports the body - from mental well-being to metabolic health.

Mental Well-Being

Myo-inositol is a second-messenger precursor studied for its role in supporting mood balance and emotional steadiness.

Cognitive Support

As a component of brain-cell signaling, myo-inositol is studied for its relationship to healthy brain function and mental clarity.

Hormonal Balance

Myo-inositol plays a role in cellular signaling pathways studied for supporting healthy hormonal balance in women.

Metabolic Wellness

Myo-inositol is studied for its role in cellular signaling pathways linked to healthy glucose metabolism and insulin sensitivity.

AOR Inositol: Supplement Facts

AOR™Inositol
English

Each Capsule contains:

  • myo-Inositol500 mg

Non-Medicinal Ingredients: None. Capsule: Hypromellose.

Recommended Use or Purpose: Aids in cellular defense, normal cell growth and differentiation for the maintenance of good health. Licensed Natural Health Product, NPN 80005752.

Recommended Dose (Adults 18 years and older): Take 1 capsule daily, with or without food, or as directed by a qualified health-care practitioner. Do not crush, blend, or mix the capsules - swallow whole. Do not exceed the recommended dose unless instructed by a health-care practitioner.

Cautions and Warnings: For adult use only. Consult a health-care practitioner prior to use if you are pregnant or breastfeeding. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Chaque capsule contient :

  • Myo-inositol500 mg

Ingrédients non médicinaux : Aucun. Capsule : Hypromellose.

Usage ou fins recommandés : Aide à la défense cellulaire, à la croissance cellulaire normale et à la différenciation pour le maintien d'une bonne santé. Produit de santé naturel homologué, NPN 80005752.

Dose recommandée (Adultes de 18 ans et plus) : Prendre 1 capsule par jour, avec ou sans nourriture, ou selon les recommandations d'un professionnel de la santé qualifié. Avaler les capsules entières; éviter de les écraser, de les briser ou de les mélanger. Ne dépassez pas la dose recommandée sauf indication contraire d'un professionnel de la santé.

Mises en garde : Pour adulte seulement. Consultez un professionnel de la santé avant de prendre ce produit si vous êtes enceinte ou si vous allaitez. Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement fermé dans un endroit frais et sec.

NPN 80005752

Pure myo-Inositol · 500 mg per capsule90 or 180 capsules · up to 6-month supplyVegan · Non-GMO · Gluten-FreeMade in Canada

Support mental well-being and healthy hormonal balance the easy way

Get AOR Inositol Caps on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR Inositol Caps

One real ingredient, 500 mg per capsule - four ways myo-inositol supports the body.

Mental Well-Being & Mood

Supports a sense of calm and balance as part of a healthy daily routine.

Cognitive Clarity

Nourishes healthy brain function to help support focus and mental sharpness.

Hormonal Balance

Supports women's hormonal balance as part of overall wellness.

Pure & Simple

500 mg of pure myo-inositol per vegan capsule - non-GMO, gluten-free, made in Canada.

How to use

Take 1 capsule

Adults (18 years and older) take 1 capsule daily, with or without food.

Stay consistent

Make it part of your daily routine, or as directed by a qualified health-care practitioner.

Swallow whole

Do not crush, blend, or mix the capsule.

Do not exceed the dose

Do not exceed the recommended daily dose unless instructed by a health-care practitioner.

What the research says about myo-inositol

Peer-reviewed studies and reviews on myo-inositol - shared for education, not as claims about this finished product. AOR Inositol Caps' claims are the statements authorized under its Natural Health Product licence, NPN 80005752.

Mood, Anxiety & Panic Research

The original placebo-controlled panic disorder trial

In a 4-week, double-blind, placebo-controlled crossover trial, 21 patients with panic disorder (with or without agoraphobia) had significantly greater reductions in panic-attack frequency, severity, and agoraphobia after 12 g/day of inositol than after placebo, with minimal side effects.

Human RCT
Benjamin et al., American Journal of Psychiatry (1995)
Mood, Anxiety & Panic Research

A controlled crossover trial in obsessive-compulsive disorder

Thirteen patients with OCD completed a double-blind, controlled crossover trial of 18 g/day of inositol versus placebo for six weeks each, and scored significantly lower on the Yale-Brown Obsessive-Compulsive Scale while taking inositol.

Human RCT
Fux et al., American Journal of Psychiatry (1996)
Mood, Anxiety & Panic Research

A meta-analysis across depression and anxiety disorders

Pooling 7 randomized trials in depression and 4 in anxiety disorders (OCD, panic disorder, PTSD), this meta-analysis found no statistically significant overall effect but noted marginally more responders with inositol than placebo in depression, with a trend toward benefit in premenstrual dysphoric disorder.

Meta-analysis
Mukai et al., Human Psychopharmacology (2013)
PCOS & Hormonal Balance Research

An umbrella review of 13 meta-analyses in PCOS

Synthesizing 13 meta-analyses of randomized trials, this umbrella review found inositol supplementation was associated with reduced LH, total and free testosterone, and androstenedione, and increased SHBG, alongside improvements in insulin-resistance markers and ovulation/pregnancy rates - though most evidence was graded low to very low certainty.

Umbrella review
Duan et al., Frontiers in Endocrinology (2026)
PCOS & Hormonal Balance Research

Nutrition-focused umbrella review of PCOS interventions

This umbrella review of 28 RCT meta-analyses on nutrition in PCOS found inositol supplementation improved fasting insulin with moderate-certainty evidence and increased ovulation rates in subfertile women with PCOS, among several nutrients showing favorable metabolic effects.

Umbrella review
Moslehi et al., Nutrition Reviews (2023)
PCOS & Hormonal Balance Research

Adding inositol to metformin therapy

In a meta-analysis of 6 RCTs (388 women with PCOS), combining metformin with inositol improved menstrual cycle regularity and reduced hirsutism scores and LH/FSH ratio compared with metformin alone, though several other measures did not reach statistical significance.

Meta-analysis
Kelly et al., Endocrine (2024)
Cognitive Function & Brain Health Research

Myo-inositol as a brain metabolite studied by MR spectroscopy

This review explains how myo-inositol is one of the major brain metabolites measurable by magnetic resonance spectroscopy, alongside NAA, choline, and glutamate, and summarizes its relevance across psychiatric and cognitive-related brain research.

Review
Maddock & Buonocore, Current Topics in Behavioral Neurosciences (2012)
Cognitive Function & Brain Health Research

Brain myo-inositol levels track with age and memory performance

In a healthy population spanning younger to older adulthood, MRS-measured myo-inositol concentration in the cingulate cortex rose with age and correlated inversely with immediate and delayed recall memory scores - observational evidence linking this brain metabolite to age-related cognitive change.

Human study
Singh et al., Neurochemistry International (2026)
Cognitive Function & Brain Health Research

The second-messenger basis for inositol's role in brain signaling

This review explains that inositol is a key intermediate of the phosphatidyl-inositol cycle, a second-messenger system used by noradrenergic, serotonergic, and cholinergic brain receptors - the mechanistic basis proposed for inositol's effects on brain and nervous-system signaling.

Review
Benjamin et al., Psychopharmacology Bulletin (1995)
Metabolic & Insulin Sensitivity Research

Comparing myo-inositol with metformin on glycemic and lipid profile

In a prospective randomized trial, women with PCOS given myo-inositol (2 g plus folic acid) saw significant cholesterol improvements regardless of body-mass index, while metformin more specifically improved fasting glucose and HOMA-IR in patients with higher BMI.

Human RCT
Stevchevska & Milenkovic, Prilozi (2025)
Metabolic & Insulin Sensitivity Research

Metabolic phenotype shapes the hormonal response to inositol

This meta-analysis of 9 RCTs (440 women) found inositol supplementation reduced testosterone and free androgen index and raised SHBG, with the most consistent improvement seen in normal-weight women - little independent effect was detected by insulin-resistance status alone.

Meta-analysis
Tienforti et al., Clinical Endocrinology (2026)
Metabolic & Insulin Sensitivity Research

A Cochrane review of insulin-sensitising agents

This Cochrane systematic review of 44 trials (3,992 women) evaluated insulin-sensitising drugs, including D-chiro-inositol, for reproductive and metabolic outcomes in PCOS, finding improved clinical pregnancy rates though no clear evidence of improved live-birth rates.

Cochrane review
Tang et al., Cochrane Database of Systematic Reviews (2012)
Safety & Tolerability Research

Comparing the safety profiles of myo-inositol and metformin

This narrative review contrasts myo-inositol, a molecule naturally present in the body, with the pharmacological agent metformin, concluding that available data - while incomplete - support a more favorable tolerability profile for myo-inositol, which lacks metformin's gastrointestinal and rare lactic-acidosis risks.

Review
Russo et al., Gynecologic and Obstetric Investigation (2025)
Safety & Tolerability Research

Head-to-head against a prescription anti-panic medication

In a crossover trial comparing inositol (up to 18 g/day) with fluvoxamine for panic disorder, the two treatments produced similar improvements in anxiety and panic-attack frequency, but nausea and tiredness were significantly more common with fluvoxamine than with inositol.

Human RCT
Palatnik et al., Journal of Clinical Psychopharmacology (2001)
Safety & Tolerability Research

Tolerability as an add-on to existing mood-stabilizer treatment

In a pilot trial of inositol added to ongoing lithium, valproate, or carbamazepine therapy for bipolar depression, inositol was well tolerated with minimal side effects and did not alter blood levels of the concurrent mood-stabilizing medications.

Human RCT
Chengappa et al., Bipolar Disorders (2000)
Comparative Inositol-Form Research

Two isomers, two different roles

This review explains that D-chiro-inositol is formed from myo-inositol via an insulin-dependent conversion, that the two isomers are normally maintained at roughly a 40:1 ratio in blood plasma, and that myo-inositol concentration in follicular fluid is studied as a marker of oocyte quality.

Review
Placidi et al., Biology (2024)
Comparative Inositol-Form Research

Opposite effects on ovarian steroid hormone production

This expert narrative review describes how myo-inositol and D-chiro-inositol exert opposite direct effects on ovarian steroidogenesis - D-chiro-inositol downregulates aromatase while myo-inositol increases aromatase and FSH-receptor expression - in addition to both modulating insulin signaling.

Review
Lentini et al., Drug Design, Development and Therapy (2025)
Comparative Inositol-Form Research

Comparing a myo-inositol/D-chiro-inositol blend with metformin

In a 12-week prospective trial, a 40:1 myo-inositol/D-chiro-inositol combination and metformin both significantly improved insulin sensitivity, SHBG, ovarian volume, and menstrual regularity in women with PCOS, with metformin showing a modest edge in some endocrine measures.

Human RCT
Gul et al., Naunyn-Schmiedeberg's Archives of Pharmacology (2025)
Foundational Biochemistry Research

Inositol's ancient evolutionary origins

This review traces inositol phospholipids across archaea, bacteria, and all eukaryotes, proposing that the inositol-1-phosphate headgroup chemistry arose in early archaea roughly three billion years ago and was carried into the common ancestor of all eukaryotic cells.

Review
Michell, Advances in Enzyme Regulation (2010)
Foundational Biochemistry Research

How phosphoinositides were linked to calcium signaling

This historical review traces how, beginning in the 1970s, the connection between phosphoinositide turnover and calcium-regulated cell processes was established, launching decades of research into inositol lipids as central second-messenger molecules.

Review
Michell, Cell Calcium (2009)
Foundational Biochemistry Research

The discovery history of inositol-based cell signaling

This historical review credits the 1950s discovery by Hokin and Hokin that receptor agonists stimulate phosphate incorporation into phospholipids as the start of inositol-lipid signaling research, tracing the field through the identification of inositol trisphosphate and diacylglycerol as second messengers.

Review
Toker, Sub-Cellular Biochemistry (2012)
Dosing & Bioavailability Research

Pharmaceutical form changes the effective dose

A pharmacokinetic trial in 20 healthy volunteers found a soft-gelatin capsule form of myo-inositol achieved blood levels similar to three-times-higher doses of the standard powder form, showing that formulation affects how much needs to be taken to reach comparable blood levels.

Human study
Carlomagno et al., Expert Opinion on Drug Delivery (2012)
Dosing & Bioavailability Research

A co-ingredient that improves absorption

In healthy volunteers, co-administering alpha-lactalbumin with myo-inositol significantly increased plasma myo-inositol concentration compared with myo-inositol alone, with in-vitro work suggesting alpha-lactalbumin peptides improve intestinal absorption.

Human & lab study
Monastra et al., Current Drug Delivery (2018)
Dosing & Bioavailability Research

The range of doses studied across conditions

This review surveys controlled inositol trials across several conditions, noting therapeutic doses studied from 6 g/day (Alzheimer's, pre-ECT) up to 18 g/day (OCD), with 12 g/day used in the original depression and panic-disorder trials - a much higher gram-scale range than typical single-capsule supplement doses.

Review
Levine, European Neuropsychopharmacology (1997)

Frequently asked questions

What is AOR Inositol Caps?

Each vegan capsule provides 500 mg of pure myo-inositol, a naturally occurring cellular signaling compound. It is a licensed Natural Health Product, NPN 80005752, that aids in cellular defense, normal cell growth and differentiation for the maintenance of good health.

How do I take it?

Adults (18 years and older) take 1 capsule daily, with or without food, or as directed by a qualified health-care practitioner. Swallow the capsule whole - do not crush, blend, or mix it.

What's the difference between the 90-capsule and 180-capsule bottles?

Both contain the same formula - 500 mg of pure myo-inositol per vegan capsule. The 90-capsule bottle is a 90-day supply at 1 capsule daily; the 180-capsule bottle is a 6-month supply.

Is it vegan and gluten-free?

Yes - AOR Inositol Caps are vegan, non-GMO and gluten-free, with no non-medicinal ingredients beyond the hypromellose capsule shell.

What's in the capsule besides myo-inositol?

Nothing else. The medicinal ingredient is myo-inositol 500 mg, and the only other component is the hypromellose capsule shell itself.

Who should check with a health-care practitioner before using it?

This product is for adult use only. Consult a health-care practitioner before use if you are pregnant or breastfeeding.

How long does one bottle last?

At the labelled dose of 1 capsule daily, the 90-capsule bottle lasts about 90 days (3 months) and the 180-capsule bottle lasts about 180 days (6 months).

Where do I buy it?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.

Pure myo-Inositol · 500 mg per capsule90 or 180 capsules · up to 6-month supplyVegan · Non-GMO · Gluten-FreeMade in Canada

Support mental well-being and healthy hormonal balance the easy way

Get AOR Inositol Caps on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80005752. AOR Inositol Caps aids in cellular defense, normal cell growth and differentiation for the maintenance of good health. The research summaries below concern myo-inositol generally - mood and hormonal-balance research, cognitive function, and metabolic research - and are educational; they are not claims about this finished product beyond its own licensed use. Read and follow the label. This product is for adult use only. Consult a health-care practitioner before use if you are pregnant or breastfeeding. Results may vary.

Important information

Safety Information

Cautions and Warnings: For adult use only. Consult a health-care practitioner prior to use if you are pregnant or breastfeeding. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place.

Indications

Recommended Use or Purpose: Aids in cellular defense, normal cell growth and differentiation for the maintenance of good health. Licensed Natural Health Product, NPN 80005752.

Ingredients

Medicinal Ingredients: myo-Inositol 500 mg per capsule. Non-medicinal Ingredients: None. Capsule: Hypromellose. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule daily, with or without food, or as directed by a qualified health-care practitioner. Do not crush, blend, or mix the capsules - swallow whole. Do not exceed the recommended dose unless instructed by a health-care practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.