AOR Hawthorn II 450mg - Leaf & Flower Extract for Cardiovascular Support | 60 Caps
Visit the AOR Store| Brand | AOR |
| Serving | 1-2 capsules (450-900 mg) |
| Licensed Natural Health Product | NPN 80064333 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- STANDARDIZED HAWTHORN LEAF & FLOWER EXTRACT: Each vegan capsule delivers 450 mg of hawthorn extract standardized to a 4-5:1 ratio, made from Crataegus laevigata leaf and flower sourced from Spain.
- SUPPORTS CARDIOVASCULAR HEALTH: Hawthorn leaves and flowers are used in herbal medicine to help support cardiovascular health in adults - a use with a long history in European herbal medicine.
- PROMOTES HEALTHY CIRCULATION: Traditionally used to help promote healthy blood flow and support normal vessel tone, complementing an active, heart-healthy lifestyle.
- SOURCE OF ANTIOXIDANTS: Hawthorn's flavonoids and oligomeric procyanidins provide antioxidant compounds that help protect cells from everyday oxidative stress.
- SIMPLE 1-2 CAPSULE DAILY ROUTINE: Take 1 to 2 capsules per day with or without food - a straightforward addition to a daily wellness routine, best used consistently for a minimum of 2 months.
- VEGAN, NON-GMO & GLUTEN-FREE: Vegetable (hypromellose) capsules with no animal-derived ingredients, formulated without gluten or genetically modified inputs.
- UP TO A 2-MONTH SUPPLY: 60 capsules per bottle - up to a 2-month supply at the standard 1-capsule daily dose, or up to a 1-month supply at 2 capsules per day.
- PREMIUM CANADIAN QUALITY SINCE 1991: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80064333.
Product Description
Hawthorn II - Standardized Hawthorn Leaf & Flower Extract
A traditional botanical for cardiovascular support. Each vegan capsule delivers 450 mg of hawthorn extract standardized to a 4-5:1 ratio, from Crataegus laevigata leaf and flower. Hawthorn has a centuries-long history of use in European herbal medicine to help support heart and circulatory health. Licensed Natural Health Product NPN 80064333.
Un botanique traditionnel pour le soutien cardiovasculaire. Chaque capsule végétalienne fournit 450 mg d'extrait d'aubépine normalisé à un ratio de 4-5:1, provenant de feuilles et de fleurs de Crataegus laevigata. Produit de santé naturel homologué. NPN 80064333.
Standardized Hawthorn Extract
450 mg hawthorn leaf and flower extract (4-5:1) per capsule - Vegan, Non-GMO, Gluten Free
Standardized 4-5:1 Extract
A concentrated hawthorn leaf and flower extract, standardized to a consistent 4-5:1 ratio for dependable potency in every capsule.
Simple Daily Dosing
Take 1 to 2 vegan capsules per day with or without food - use consistently for a minimum of 2 months to notice beneficial effects.
What AOR Hawthorn II Supports
Hawthorn leaf and flower extract has a long history in traditional cardiovascular support - here is what it may help with.
Heart Function Support
Helps maintain overall cardiovascular health as part of a heart-healthy lifestyle.
Healthy Circulation
Traditionally used to promote normal blood flow and healthy vessel tone.
Antioxidant Protection
Provides flavonoid and procyanidin compounds that help protect cells against everyday oxidative stress.
Gentle, Standardized Botanical
A standardized 4-5:1 hawthorn extract traditionally used for wellness and vitality, gentle enough for daily use.
AOR Hawthorn II: Supplement Facts
Each Vegan Capsule Contains:
- Hawthorn extract (4-5:1) (Crataegus laevigata leaf and flower, from Spain)450 mg
Non-Medicinal Ingredients: Colloidal anhydrous silica, sodium stearyl fumarate, microcrystalline cellulose, maltodextrin (corn). Capsule: hypromellose.
Recommended Use or Purpose: Hawthorn leaves and flowers are used in herbal medicine to help support cardiovascular health in adults.
Recommended Dose (Adults 18 years and older): Take 1 to 2 capsules per day with or without food, or as directed by a qualified health care practitioner. Use for a minimum of 2 months to see beneficial effects. Do not crush, mix or blend capsules; swallow capsules whole. Do not exceed the daily dose unless instructed by a health care practitioner.
Cautions and Warnings: Consult a health care practitioner before use if you are taking cardiac glycosides such as digitalis or digoxin, or blood pressure medication. Consult a health care practitioner if symptoms persist or worsen. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place, away from children. Allergen: Corn.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Chaque capsule végétalienne contient :
- Extrait d'aubépine (4-5:1) (feuilles et fleurs de Crataegus laevigata, d'Espagne)450 mg
Ingrédients non médicinaux : Silice colloïdale anhydre, stéarylfumarate de sodium, cellulose microcristalline, maltodextrine (maïs). Capsule : hypromellose.
Usage ou fins recommandés : Les feuilles et les fleurs d'aubépine sont utilisées en phytothérapie pour soutenir la santé cardiovasculaire des adultes.
Dose recommandée (adultes de 18 ans et plus) : Prendre 1 à 2 capsules par jour avec ou sans nourriture, ou selon les recommandations d'un professionnel de la santé qualifié. Utiliser pendant au moins 2 mois pour constater les effets bénéfiques. Ne pas écraser, mélanger ou broyer les capsules; avaler les capsules entières. Ne pas dépasser la dose quotidienne, sauf indication contraire d'un professionnel de la santé.
Mises en garde : Consulter un professionnel de la santé avant l'utilisation si vous prenez des glycosides cardiaques tels que la digitaline ou la digoxine, ainsi que des médicaments contre l'hypertension. Consulter un professionnel de la santé si les symptômes persistent ou s'aggravent. Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement dans un endroit frais et sec, hors de la portée des enfants. Allergène : Maïs.
NPN 80064333
Support your heart & circulation the natural way
Get AOR Hawthorn II on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Hawthorn II
A standardized, traditional botanical for cardiovascular support - premium AOR quality.
Standardized potency
450 mg of hawthorn extract standardized to a 4-5:1 ratio in every capsule, for consistent, dependable strength.
Heart & circulation support
Hawthorn leaves and flowers are used in herbal medicine to help support cardiovascular health and healthy circulation.
Vegan, simple formula
Vegetable capsules with just four non-medicinal ingredients - non-GMO and gluten-free.
Premium Canadian brand
AOR - Advanced Orthomolecular Research, since 1991. NPN 80064333.
How to use it
Take 1-2 capsules daily
Adults (18 years and older): take 1 to 2 capsules per day, with or without food.
Swallow whole
Do not crush, mix or blend capsules - swallow them whole, and do not exceed the daily dose unless directed by a health care practitioner.
Use consistently for at least 2 months
Hawthorn works gradually - use for a minimum of 2 months to notice beneficial effects, or as directed by a qualified health care practitioner.
What the research says about hawthorn (Crataegus)
Educational summaries of published research on Crataegus (hawthorn), including studies of berry, leaf and flower preparations; not product-specific claims. AOR Hawthorn II's own claim is the traditional use authorized under NPN 80064333, based on standardized hawthorn leaf and flower extract (4-5:1).
Cochrane review: improved workload and symptoms
A Cochrane meta-analysis of 14 trials (855 patients with chronic heart failure) found hawthorn extract, used alongside conventional treatment, significantly improved maximal workload, exercise tolerance, and symptoms like breathlessness and fatigue versus placebo.
Cochrane meta-analysisLarge SPICE trial: safe as an add-on therapy
In a 2,681-patient, 24-month randomized trial, hawthorn extract WS 1442 added to standard heart-failure therapy was well tolerated, with a signal toward fewer sudden cardiac deaths in patients with less advanced disease.
Human RCTDose-dependent gains in exercise capacity
A randomized trial in 209 patients with more advanced (NYHA class III) heart failure found hawthorn extract WS 1442 improved maximal tolerated workload and symptom scores in a dose-dependent way, and was well tolerated.
Human RCTHawthorn + hyperoside lowered blood pressure in rats
Hawthorn fruit extract and its compound hyperoside significantly reduced blood pressure in spontaneously hypertensive rats over 7 weeks, acting in part through bile-acid and inflammation-related pathways.
Animal studyTrial in mildly hypertensive adults
A randomized, placebo-controlled crossover study of a hawthorn fruit extract drink in adults with mild hypertension and/or high cholesterol found a trend toward fewer adverse metabolic effects versus placebo over 8 weeks.
Human RCTDose-dependent reduction in heart rate and pressure
In rats, increasing doses of a Crataegus extract produced a dose- and time-dependent decrease in heart rate and mean arterial pressure, linked to muscarinic-receptor stimulation and enhanced nitric-oxide release.
Animal studySupports the body's own antioxidant defenses
A review of hawthorn's mechanisms describes activation of the body's own antioxidant defenses and AMPK cell signaling as key routes behind its traditional cardiovascular and hepatic benefits.
ReviewFruit compounds show strong free-radical scavenging
Laboratory assays of hawthorn fruit extracts identified chlorogenic acid and hyperoside as potent free-radical scavengers, supporting hawthorn's traditional role as a source of dietary antioxidants.
Laboratory studyReduced oxidative stress markers in a heart-failure model
An ethanol extract of hawthorn fruit lowered inflammatory cytokines and oxidative-stress markers while improving heart-function measurements in rats with drug-induced chronic heart failure.
Animal studyStandardized extract raised exercise tolerance
In a randomized trial of 143 patients with NYHA class II heart failure, a standardized Crataegus extract significantly increased bicycle exercise tolerance compared with placebo over 8 weeks.
Human RCTHERB-CHF: a balanced, real-world result
A 120-patient, 6-month randomized trial found hawthorn 450 mg twice daily added no significant improvement in 6-minute walk distance when layered on top of contemporary, evidence-based heart-failure medication - a reminder that hawthorn complements, rather than replaces, prescribed care.
Human RCTPooled analysis: workload and ejection-fraction gains
A pooled analysis of 687 patients across 10 clinical trials found Crataegus extract improved maximal workload, left-ventricular ejection fraction, and the pressure-heart-rate product versus placebo, with benefits comparable in men and women.
Pooled analysisPharmacokinetic study: hawthorn leaves & flowers plus digoxin
A crossover study in 8 healthy volunteers combining digoxin with a standardized hawthorn-leaf-and-flower extract for 3 weeks found no statistically significant change in digoxin's blood levels, while noting hawthorn's flavonoids can affect the same transport protein digoxin uses - a reason medical supervision matters when combining them.
Human PK studyClinical review flags hawthorn among digoxin-interacting herbs
A widely cited review of herb-drug interactions specifically names hawthorn among the botanicals that can interfere with digoxin, either pharmacodynamically or with digoxin blood-level monitoring.
ReviewGenerally well tolerated, but interactions warrant caution
A systematic review of 24 clinical studies (5,577 patients) found hawthorn-only preparations were generally well tolerated with mostly mild adverse events, while cautioning that unsupervised use alongside other cardiac medications can be a problem.
Systematic reviewExpert panel weighs hawthorn among heart-failure nutraceuticals
An International Lipid Expert Panel position paper reviewed clinical evidence for hawthorn alongside coenzyme Q10, L-carnitine, vitamin D and other nutraceuticals in heart failure, noting improvements in quality of life and functional measures with generally minimal side effects, particularly in earlier disease stages.
Expert position paperSystematic review situates hawthorn among heart-failure options
A systematic review of nutraceuticals in heart-failure patients evaluated hawthorn extract alongside coenzyme Q10, beetroot juice, magnesium and other options, concluding most - hawthorn included - need larger, longer trials before firm conclusions on outcomes can be drawn.
Systematic reviewPrimary-care review of evidence-informed heart options
A primary-care review of complementary cardiovascular therapies discussed hawthorn together with coenzyme Q10 as of possible benefit in congestive heart failure, alongside garlic, red yeast rice and other commonly used options.
ReviewNew procyanidins isolated from leaves and flowers
Chemists isolated and structurally characterized previously unreported oligomeric procyanidins - including a new trimer and pentamer - from hawthorn (Crataegus) leaves and flowers for the first time.
PhytochemistryMapping the procyanidin content of leaf and flower
A validated chromatography method quantified oligomeric and polymeric procyanidins in hawthorn leaf and flower, finding consistent levels (about 20-45 mg/g) across the growing season, with the strongest concentration in the flowers.
Analytical chemistryThe marker compounds behind standardization
A review of Crataegus oxyacantha phytochemistry describes oligomeric procyanidins and flavone/flavonol flavonoids as the marker compounds used to standardize hawthorn extracts for consistent activity.
ReviewA documented history from Indigenous to European medicine
A review of Crataegus chemistry traces hawthorn's use back to the 1800s in North America, where Indigenous peoples used it for heart and digestive complaints, alongside a long parallel history of use in Europe and China.
Historical reviewFirst described in a classical Chinese medical text
Chinese hawthorn (Crataegus pinnatifida), known as Shanzha, was first documented in the classical text Xinxiu Ben Cao and has a long history of use for digestion and cardiovascular support.
Ethnopharmacology reviewA long-favored herbal remedy in European medicine
A clinical review describes hawthorn as a long-favored herbal remedy in Europe, with the German Commission E historically recognizing standardized hawthorn leaf-and-flower extracts for early-stage heart failure.
Clinical reviewFrequently asked questions
What is AOR Hawthorn II and what does it do?
AOR Hawthorn II is a standardized hawthorn (Crataegus laevigata) leaf and flower extract. Hawthorn leaves and flowers are used in herbal medicine to help support cardiovascular health in adults.
How do I take it?
Adults (18 years and older) take 1 to 2 capsules per day with or without food, or as directed by a qualified health care practitioner. Swallow capsules whole - do not crush, mix or blend them.
How long before I notice benefits?
Use for a minimum of 2 months to see beneficial effects, since hawthorn works gradually with consistent daily use.
Is this hawthorn made from the berry, the leaf, or the flower?
This extract is made from Crataegus laevigata leaf and flower (sourced from Spain), standardized to a 4-5:1 ratio - not the berry.
Can I take this with heart or blood-pressure medication?
Consult a health care practitioner before use if you are taking cardiac glycosides such as digitalis or digoxin, or blood pressure medication. Hawthorn can interact with these medications, so medical supervision is important.
Is it vegan and allergen-friendly?
Yes - the vegetable (hypromellose) capsules are vegan, non-GMO and gluten-free. The only allergen present is corn, from the maltodextrin used as a non-medicinal ingredient.
How long does one bottle last?
Each bottle has 60 capsules - up to a 2-month supply at 1 capsule per day, or up to a 1-month supply at 2 capsules per day.
Is it made in Canada?
Yes. It is manufactured in Canada by AOR (Advanced Orthomolecular Research) and licensed by Health Canada under NPN 80064333.
Support your heart & circulation the natural way
Get AOR Hawthorn II on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80064333. Hawthorn leaves and flowers are used in herbal medicine to help support cardiovascular health in adults. The research summaries below concern hawthorn (Crataegus) generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use if you are taking cardiac glycosides such as digitalis or digoxin, or blood pressure medication, or if symptoms persist or worsen. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner before use if you are taking cardiac glycosides such as digitalis or digoxin, or blood pressure medication. Consult a health care practitioner if symptoms persist or worsen. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place, away from children. Allergen: Corn.
Indications
Recommended Use or Purpose: Hawthorn leaves and flowers are used in herbal medicine to help support cardiovascular health in adults.
Ingredients
Medicinal Ingredient (per capsule): Hawthorn extract (4-5:1) 450 mg (source: Crataegus laevigata leaf and flower from Spain). Non-medicinal ingredients: Colloidal anhydrous silica, sodium stearyl fumarate, microcrystalline cellulose, maltodextrin (corn). Capsule: hypromellose. NMIs are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 18 years and older): Take 1 to 2 capsules per day with or without food, or as directed by a qualified health care practitioner. Use for a minimum of 2 months to see beneficial effects. Do not crush, mix or blend capsules; swallow capsules whole. Do not exceed the daily dose unless instructed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.