AOR Fem Calm 248mg - Chasteberry Rhodiola & Ashwagandha for Hormonal Balance | 60 Caps
Visit the AOR Store| Brand | AOR |
| Serving | 2 capsules (248 mg formula per capsule) |
| Licensed Natural Health Product | NPN 80047096 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- SIX REAL ACTIVES IN EVERY SERVING: Chasteberry (Vitex agnus-castus) extract, rhodiola rosea extract, ashwagandha (Withania somnifera) extract, vitamin B6 (as pyridoxal-5-phosphate), vitamin B12 (as methylcobalamin) and folic acid (as calcium L-5-MTHF) - two capsules daily.
- HELPS RELIEVE PREMENSTRUAL SYMPTOMS: Used in Herbal Medicine to help relieve premenstrual symptoms, drawing on chasteberry's traditional and clinically studied role in premenstrual and cyclical symptom relief.
- HORMONE NORMALIZER FOR CYCLE IRREGULARITIES: Used in Herbal Medicine as a hormone normalizer to help stabilize menstrual cycle irregularities - use for a minimum of 3 months to see beneficial effects.
- ALSO HELPS WITH MENOPAUSE SYMPTOMS: Used in Herbal Medicine to help relieve symptoms associated with menopause, such as hot flashes.
- ADAPTOGENS FOR EVERYDAY STRESS RESILIENCE: Rhodiola rosea and ashwagandha are traditionally used as adaptogens, alongside vitamin B6's role in the body's ability to metabolize nutrients and vitamin B12/folate's roles in red blood cell formation and energy metabolism.
- SIMPLE ONCE-DAILY DOSING: Take 2 capsules once daily with or without food. Use for a minimum of 3 months to see beneficial effects for menstrual cycle irregularities.
- VEGAN, CLEAN FORMULA: Vegan, non-GMO and gluten-free in a hypromellose capsule. Contains corn (from maltodextrin) - avoid if you have a corn allergy.
- TRUSTED CANADIAN QUALITY: Manufactured in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), a licensed Natural Health Product, NPN 80047096.
Product description
AOR Fem Calm 248mg - Chasteberry, Rhodiola & Ashwagandha for Women's Hormonal Balance
A closer look at AOR Fem Calm - chasteberry, rhodiola rosea and ashwagandha extracts combined with vitamin B6, B12 and folic acid to help relieve premenstrual symptoms, normalize hormone-driven cycle irregularities, and ease menopause symptoms like hot flashes. Licensed Natural Health Product, NPN 80047096. Licensed Natural Health Product NPN 80047096.
Un regard plus approfondi sur AOR Fem Calm - extraits de Vitex, de rhodiole et d'ashwagandha combinés avec les vitamines B6, B12 et l'acide folique pour aider à soulager les symptômes prémenstruels, normaliser les irrégularités du cycle menstruel et soulager les symptômes de la ménopause comme les bouffées de chaleur. Produit de santé naturel homologué, NPN 80047096.
Why AOR Fem Calm
Chasteberry, rhodiola and ashwagandha combined with three supportive B vitamins - not a single-herb formula.
Backed by Real Ingredient Research
Chasteberry's hormone-normalizing effect, rhodiola's adaptogenic role and ashwagandha's stress-supportive properties are each summarized from real published research below.
The AOR Difference
Six real medicinal ingredients at meaningful doses in one vegan capsule - non-GMO, gluten-free and made in Canada.
Advanced Ingredients, Superior Results
Six real ingredients, each contributing a distinct role - here is what chasteberry, rhodiola, ashwagandha and the three B vitamins each bring to the formula.
Chasteberry Extract (Vitex agnus-castus)
A traditional herbal remedy for women's cycles, used in Herbal Medicine to help relieve premenstrual symptoms, as a hormone normalizer to help stabilize menstrual cycle irregularities, and to help relieve menopause symptoms like hot flashes - thought to act through dopamine-receptor binding that helps lower elevated prolactin.
20 mg per serving (10-12:1 extract)Rhodiola Rosea Extract
A traditional adaptogen used to help the body resist the effects of stress and support mental and physical performance, standardized to its two key marker compounds, rosavin and salidroside.
144 mg per serving (1-6% rosavin, 0.8-3% salidroside)Ashwagandha Extract (Withania somnifera)
An Ayurvedic adaptogenic herb studied for its role in supporting the body's stress response and emotional well-being, alongside chasteberry and rhodiola in this formula.
300 mg per serving (10:1 extract)
Vitamin B6 (as Pyridoxal-5-Phosphate)
The bioactive, ready-to-use form of vitamin B6, a cofactor the body needs to synthesize neurotransmitters like serotonin and GABA and one of the most consistently studied nutrients for premenstrual mood symptoms.
30 mg per servingVitamin B12 (as Methylcobalamin)
The methylated, bioactive form of vitamin B12, supporting energy metabolism and the formation of red blood cells.
1 mg per servingFolic Acid (as Calcium L-5-MTHF)
A bioactive, ready-to-use form of folate that helps in the formation of red blood cells and supports the body's ability to metabolize nutrients.
300 mcg per servingAOR Fem Calm: Supplement Facts
Medicinal Ingredients (per 2 capsules)
- Chasteberry Extract (Vitex agnus-castus, 10-12:1 extract)20 mg
- Rhodiola Rosea Extract (1-6% rosavin, 0.8-3% salidroside)144 mg
- Ashwagandha Extract (Withania somnifera, 10:1 extract)300 mg
- Vitamin B6 (as Pyridoxal-5-Phosphate)30 mg
- Vitamin B12 (as Methylcobalamin)1 mg
- Folic Acid (as Calcium L-5-MTHF)300 mcg
Non-Medicinal Ingredients: Silicon dioxide, microcrystalline cellulose, maltodextrin (corn), dextrin (tapioca). Capsule: hypromellose. Contains corn.
Recommended Use or Purpose: Used in Herbal Medicine to help relieve premenstrual symptoms. Used in Herbal Medicine as a hormone normalizer to help stabilize menstrual cycle irregularities. Used in Herbal Medicine to help relieve symptoms associated with menopause, such as hot flashes. Licensed Natural Health Product, NPN 80047096.
Recommended Dose (Adults 18 years and older): Take 2 capsules once daily with or without food, or as directed by a qualified health care practitioner. Use for a minimum of 3 months to see beneficial effects for menstrual cycle irregularities. Do not open capsules, as this may compromise the stability of the medicinal ingredients. Do not exceed the recommended dose unless instructed by a health care practitioner.
Cautions and Warnings: Do not use if you have bipolar disorder or bipolar spectrum disorder, or immediately before bed. Do not use if you are pregnant, breastfeeding or trying to conceive, unless you have consulted a health care practitioner. Consult a health care practitioner prior to use if you are taking hormone-containing medication such as progesterone preparations, oral contraceptives or hormone replacement therapy (HRT), or if you are taking antidepressant medication. Consult a health care practitioner if you have a thyroid disorder or autoimmune condition. Consumption with alcohol, drugs or other natural health products with sedative properties is not recommended. May cause irritability and insomnia, in which case discontinue use. Consult a health care practitioner if symptoms persist or worsen. Do not open capsules, as this may compromise the stability of the medicinal ingredients. Keep out of reach of children. Contains corn.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Ingrédients médicinaux (par 2 capsules)
- Extrait de Vitex (Vitex agnus-castus, extrait 10-12:1)20 mg
- Extrait de rhodiole (1-6 % rosavine, 0,8-3 % salidroside)144 mg
- Extrait d'ashwagandha (Withania somnifera, extrait 10:1)300 mg
- Vitamine B6 (sous forme de phosphate de pyridoxal)30 mg
- Vitamine B12 (sous forme de méthylcobalamine)1 mg
- Acide folique (sous forme de L-5-MTHF de calcium)300 mcg
Ingrédients non médicinaux : Dioxyde de silicium, cellulose microcristalline, maltodextrine (maïs), dextrine (tapioca). Capsule : hypromellose. Contient du maïs.
Usage ou fins recommandés : Utilisé en phytothérapie pour aider à soulager les symptômes prémenstruels. Utilisé en phytothérapie comme normalisateur hormonal pour aider à stabiliser les irrégularités du cycle menstruel. Utilisé en phytothérapie pour aider à soulager les symptômes associés à la ménopause, tels que les bouffées de chaleur. Produit de santé naturel homologué, NPN 80047096.
Dose recommandée (adultes de 18 ans et plus) : Prendre 2 capsules une fois par jour avec ou sans nourriture, ou selon les recommandations d'un professionnel de la santé qualifié. Utiliser pendant au moins 3 mois pour constater les effets bénéfiques sur les irrégularités du cycle menstruel. Ne pas ouvrir les capsules, car cela pourrait compromettre la stabilité des ingrédients médicinaux. Ne pas dépasser la dose recommandée sauf indication contraire d'un professionnel de la santé.
Mises en garde et précautions : Ne pas utiliser si vous souffrez de trouble bipolaire ou de trouble du spectre bipolaire, ou immédiatement avant le coucher. Ne pas utiliser si vous êtes enceinte, si vous allaitez ou si vous essayez de concevoir, à moins d'avoir consulté un professionnel de la santé. Consultez un professionnel de la santé avant l'utilisation si vous prenez des médicaments contenant des hormones tels que des préparations à base de progestérone, des contraceptifs oraux ou un traitement hormonal substitutif (THS), ou si vous prenez des antidépresseurs. Consultez un professionnel de la santé si vous avez un trouble thyroïdien ou une condition auto-immune. La consommation avec de l'alcool, des drogues ou d'autres produits de santé naturels ayant des propriétés sédatives n'est pas recommandée. Peut provoquer de l'irritabilité et de l'insomnie, auquel cas cessez l'utilisation. Consultez un professionnel de la santé si les symptômes persistent ou s'aggravent. Ne pas ouvrir les capsules, car cela pourrait compromettre la stabilité des ingrédients médicinaux. Garder hors de la portée des enfants. Contient du maïs.
NPN 80047096
Support hormonal balance and everyday emotional wellness
Get AOR Fem Calm on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Fem Calm
Three traditional botanicals plus three supportive B vitamins, working together for women's everyday wellness.
Premenstrual Symptom Relief
Used in Herbal Medicine to help relieve premenstrual symptoms.
Hormone Normalizer
Used in Herbal Medicine as a hormone normalizer to help stabilize menstrual cycle irregularities.
Menopause Symptom Support
Used in Herbal Medicine to help relieve symptoms associated with menopause, such as hot flashes.
Premium Canadian Brand
AOR - Advanced Orthomolecular Research, since 1991. Vegan, non-GMO, gluten-free. NPN 80047096.
Inside every serving
Two capsules provide chasteberry, rhodiola rosea and ashwagandha extracts alongside vitamin B6, B12 and folic acid (as calcium L-5-MTHF) - a multi-ingredient formula for women's everyday hormonal and emotional wellness.
How to use
Take 2 capsules daily
Adults (18 years and older) take 2 capsules once daily with or without food, or as directed by a qualified health care practitioner.
Give it time
Use for a minimum of 3 months to see beneficial effects for menstrual cycle irregularities.
Do not open capsules
Swallow capsules whole - opening them may compromise the stability of the medicinal ingredients.
Know when to check in
Consult a health care practitioner if symptoms persist or worsen, or before use if you take hormone-containing medication or antidepressants.
What the research says about chasteberry, rhodiola, ashwagandha and B vitamins
Peer-reviewed studies and reviews on the individual ingredients in Fem Calm - shared for education, not as claims about this finished product. Fem Calm's own claims are the statements authorized under its Natural Health Product licence, NPN 80047096.
Named among options clinicians can consider for PMS/PMDD
A clinical review for family physicians lists cognitive behavior therapy, exercise, acupuncture/acupressure and the herb Vitex agnus-castus among approaches that may be used to help relieve premenstrual syndrome and premenstrual dysphoric disorder symptoms.
Clinical reviewHow chasteberry acts across the reproductive system
A narrative review describes how Vitex agnus-castus and its constituents act on hypothalamic, pituitary and ovarian hormones and dopamine receptors, historically supporting its use for menstrual disorders, premenstrual syndrome and cyclic mastalgia.
ReviewMeta-analysis: effective for cyclic breast pain, a common PMS symptom
A systematic review and meta-analysis of 25 studies found Vitex agnus-castus relieved breast pain intensity and lowered elevated prolactin in reproductive-age patients, at a typical dose of 20-40 mg/day for 3 months, with only mild and reversible adverse events.
Meta-analysisRCT: reduced anxiety, stress and cortisol
A randomized, placebo-controlled trial of a standardized ashwagandha extract found Hamilton Anxiety, GAD-7 and Perceived Stress Scale scores fell by 27-51%, with cortisol declining about 29%, and no serious adverse events over 60 days.
Human RCTSustained-release extract lowered perceived stress
A randomized, placebo-controlled trial of a once-daily sustained-release ashwagandha root extract found 150 mg and 300 mg doses reduced Perceived Stress Scale scores by 38.6% and 41.6% and improved sleep quality, with serum cortisol significantly reduced at the 300 mg dose.
Human RCTMeta-analysis of 23 trials: cortisol down, serotonin up
A systematic review and meta-analysis of 23 randomized trials (1,706 participants) found oral ashwagandha significantly reduced cortisol and increased serotonin, with testosterone rising in men but not in women.
Meta-analysisClassic trial: less fatigue during demanding night shifts
A double-blind, crossover study in young physicians found a standardized Rhodiola rosea extract (SHR-5) significantly improved a composite mental-fatigue index measuring associative thinking, short-term memory, calculation and concentration after night duty, versus placebo.
Human RCTClinical evidence review: alleviating stress-induced fatigue
A review of Rhodiola rosea's traditional use for stress-induced fatigue and its clinical literature concludes the accumulated evidence provides an encouraging basis for its efficacy in managing various aspects of stress-induced conditions.
ReviewSystematic review of randomized trials
A systematic review of 11 randomized controlled trials concluded Rhodiola rosea may have beneficial effects on physical performance, mental performance and certain mental health conditions, with only a few mild adverse events reported.
Systematic reviewSystematic review: B6 consistently helped psychological PMS symptoms
A systematic review of 31 randomized controlled trials (3,254 participants) found treatment with vitamin B6, calcium and zinc consistently had significant positive effects on the psychological symptoms of premenstrual syndrome.
Systematic reviewRCT: B6 comparable to a broader micronutrient formula for PMS
A randomized, treatment-controlled trial found vitamin B6 (80 mg/day) produced a medium effect-size reduction in PMS symptoms over three menstrual cycles, with 60% of participants in full symptom remission - comparable to a broad-spectrum micronutrient formula.
Human RCTSystematic review: B6 combined with magnesium eased premenstrual anxiety
A systematic review of supplementation and female stress found combined magnesium and vitamin B6 reduced premenstrual anxiety (though neither showed an effect alone for this outcome), and vitamin B6 alone reduced anxiety in older women.
Systematic reviewLower B12 linked to postpartum depression risk
A cross-sectional study of 434 postpartum Indian women found those in the lowest vitamin B12 quartile had 4.53 times higher odds of probable postpartum depression than women with higher B12 status.
Human studyMeta-analysis: folic acid supplementation and perinatal mood
A meta-analysis of 15 studies covering 26,275 women found continuous folic acid supplementation during pregnancy was associated with a lower incidence of perinatal depressive symptoms.
Meta-analysisB-vitamin inadequacy common in adults with mood disorders
A survey of 97 adults with mood disorders found a larger proportion fell below the estimated average requirement for vitamin B6, vitamin B12 and folate than in general-population nutrition-survey comparison data.
Human studyAshwagandha extract well tolerated in a 12-week RCT
A randomized, placebo-controlled trial of a 125 mg ashwagandha formulation over 84 days found significant improvements in stress, anxiety and sleep-quality measures, with the product well tolerated and no related adverse events among all 90 completers.
Human RCTChasteberry: mild, reversible side effects across trials
A review of randomized and non-randomized studies of Vitex agnus-castus for mastalgia concluded that adverse events following treatment are mild and reversible across the reviewed literature.
ReviewQuality control matters: many rhodiola products misidentified
An analytical study of 13 commercial dietary supplements claiming to contain Rhodiola rosea found nearly 60% did not contain the declared amount of rhodiola root/rhizome or its characteristic marker compounds, underscoring why standardized, verified extracts matter.
Lab analysisSystematic review of 24 RCTs on ashwagandha and rhodiola together
A systematic review of 24 randomized controlled trials (19 on ashwagandha, 5 on rhodiola) found both herbs produced multi-dimensional adaptogenic effects - reduced stress and anxiety, improved sleep and cognition - acting via regulation of the hypothalamic-pituitary-adrenal axis, neurotransmission and hormonal pathways.
Systematic reviewComparing adaptogenic plants: shared mechanisms, different plants
A literature review of plant-derived adaptogens identified Withania somnifera (ashwagandha) and Rhodiola species among the most-investigated, sharing stress-modulatory, antioxidant and anti-fatigue mechanisms of action.
ReviewPilot RCT: a rhodiola-and-B6 combination for PMS mood
A randomized, double-blind, placebo-controlled pilot study of a supplement containing GABA, rhodiola rosea, vitamin B6 and melatonin found significant within-group improvement in total antioxidant status, mood state profile and affective PMS symptoms over 3 months.
Human RCT (pilot)The dopamine-prolactin mechanism behind chasteberry's 'hormone normalizer' effect
A foundational review describes how chasteberry's diterpene compounds bind dopamine D2 receptors and suppress prolactin release from the pituitary - the proposed mechanism behind its cycle-normalizing, premenstrual-symptom-easing effect.
ReviewClassic lab study: chasteberry extract directly suppresses prolactin
A laboratory study found Vitex agnus-castus extracts inhibited basal and TRH-stimulated prolactin secretion from rat pituitary cells, an effect blocked by a dopamine-receptor blocker - confirming a dopaminergic mechanism of action.
Lab studyModern molecular docking confirms the dopamine-receptor mechanism
Using cell-based assays and molecular docking, researchers isolated specific chasteberry diterpenes and triterpenes and confirmed their binding activity at the dopamine D2 receptor, refining the molecular basis first described decades earlier.
Lab studyFrequently asked questions
What is AOR Fem Calm and what does it do?
AOR Fem Calm combines chasteberry, rhodiola rosea and ashwagandha extracts with vitamin B6, B12 and folic acid. It is used in Herbal Medicine to help relieve premenstrual symptoms, as a hormone normalizer to help stabilize menstrual cycle irregularities, and to help relieve symptoms associated with menopause such as hot flashes.
How do I take it?
Adults (18 years and older) take 2 capsules once daily with or without food, or as directed by a qualified health care practitioner. Use for a minimum of 3 months to see beneficial effects for menstrual cycle irregularities.
Who should not take Fem Calm?
Do not use if you have bipolar disorder or bipolar spectrum disorder, or immediately before bed. Do not use if you are pregnant, breastfeeding or trying to conceive, unless you have consulted a health care practitioner.
I take hormonal medication or antidepressants - is this safe for me?
Consult a health care practitioner before use if you are taking hormone-containing medication such as progesterone preparations, oral contraceptives or hormone replacement therapy, or if you are taking antidepressant medication.
Can I take it with alcohol or other calming supplements?
Consumption with alcohol, drugs or other natural health products with sedative properties is not recommended. If you notice irritability or insomnia, discontinue use.
What is the folic acid in this product?
It is calcium L-5-MTHF, a bioactive, ready-to-use form of folate, providing 300 mcg per 2-capsule serving.
Does it contain allergens?
Yes - it contains corn (from maltodextrin). Avoid it if you have a corn allergy. It is otherwise vegan, non-GMO and gluten-free.
Where do I buy it?
Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.
Support hormonal balance and everyday emotional wellness
Get AOR Fem Calm on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80047096. Fem Calm is used in Herbal Medicine to help relieve premenstrual symptoms, as a hormone normalizer to help stabilize menstrual cycle irregularities, and to help relieve symptoms associated with menopause such as hot flashes. The research summaries below concern the ingredients chasteberry (Vitex agnus-castus), rhodiola rosea, ashwagandha (Withania somnifera), vitamin B6, vitamin B12 and folate individually and are educational - they are not claims about this finished product. Read and follow the label. Do not use if you have bipolar disorder, or if you are pregnant, breastfeeding or trying to conceive, unless you have consulted a health care practitioner. Consult a health care practitioner if you are taking hormone-containing medication or antidepressants. Results may vary.
Important information
Safety Information
Cautions and Warnings: Do not use if you have bipolar disorder or bipolar spectrum disorder, or immediately before bed. Do not use if you are pregnant, breastfeeding or trying to conceive, unless you have consulted a health care practitioner. Consult a health care practitioner prior to use if you are taking hormone-containing medication such as progesterone preparations, oral contraceptives or hormone replacement therapy (HRT), or if you are taking antidepressant medication. Consult a health care practitioner if you have a thyroid disorder or autoimmune condition. Consumption with alcohol, drugs or other natural health products with sedative properties is not recommended. May cause irritability and insomnia, in which case discontinue use. Consult a health care practitioner if symptoms persist or worsen. Do not open capsules, as this may compromise the stability of the medicinal ingredients. Keep out of reach of children. Contains corn.
Indications
Recommended Use or Purpose: Used in Herbal Medicine to help relieve premenstrual symptoms. Used in Herbal Medicine as a hormone normalizer to help stabilize menstrual cycle irregularities. Used in Herbal Medicine to help relieve symptoms associated with menopause, such as hot flashes. Licensed Natural Health Product, NPN 80047096.
Ingredients
Medicinal Ingredients (per 2 capsules): Chasteberry extract (Vitex agnus-castus, 10-12:1 extract) 20 mg, Rhodiola rosea extract (1-6% rosavin, 0.8-3% salidroside) 144 mg, Ashwagandha extract (Withania somnifera, 10:1 extract) 300 mg, Vitamin B6 (as Pyridoxal-5-Phosphate) 30 mg, Vitamin B12 (as Methylcobalamin) 1 mg, Folic Acid (as calcium L-5-MTHF) 300 mcg. Non-medicinal ingredients: Silicon dioxide, microcrystalline cellulose, maltodextrin (corn), dextrin (tapioca). Capsule: hypromellose. Contains corn. NMIs are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 18 years and older): Take 2 capsules once daily with or without food, or as directed by a qualified health care practitioner. Use for a minimum of 3 months to see beneficial effects for menstrual cycle irregularities. Do not open capsules, as this may compromise the stability of the medicinal ingredients. Do not exceed the recommended dose unless instructed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.