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Health Canada NPN 80134241 506.66 mg Deglycyrrhizinated Licorice Extract Vegan - Non-GMO - Gluten-Free 90 Chewable Tablets - Up to a 1-Month Supply
DGL Licorice RootDGL Licorice Root - benefits and key ingredients DGL Licorice Root - lifestyleDGL Licorice Root - ingredientsDGL Licorice Root - supplement facts panel

AOR DGL Deglycyrrhizinated Licorice Root 507mg - Digestive Comfort | 90 Chewable Tablets

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$38.96 CAD
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BrandAOR
Serving1 chewable tablet
Licensed Natural Health ProductNPN 80134241
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • RELIEVES ABDOMINAL PAIN & BURNING: Used in Herbal Medicine to help relieve abdominal pain and burning sensation in the stomach (demulcent) and minor inflammations of the gastrointestinal tract.
  • DEGLYCYRRHIZINATED FOR A MILDER PROFILE: Processed so the finished tablet contains no more than 3% of the glycyrrhizin naturally found in licorice root - Health Canada's own DGL monograph carries no contraindications and no duration-of-use limit.
  • CHEWABLE, LEMON-FLAVOURED TABLETS: 90 chewable tablets - not capsules - with a natural lemon flavour. Chew between meals or 20 minutes before meals so the extract mixes with saliva.
  • 506.66 MG OF DGL EXTRACT PER TABLET: Each tablet delivers deglycyrrhizinated licorice root extract 5.921:1 (3000 mg dried herb equivalent), dosed within Health Canada's permitted range for this ingredient.
  • VEGAN, NON-GMO & GLUTEN-FREE: A clean formula sweetened with xylitol and monk fruit extract - vegan, non-GMO and gluten-free.
  • UP TO A 1-MONTH SUPPLY: 90 tablets at 1 tablet, 3 times per day, lasts up to a month of daily use.
  • PREMIUM CANADIAN QUALITY: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80134241.
  • TRUSTED SINCE 1991: From AOR - three decades of science-based, evidence-informed formulations manufactured in Canada to high quality standards.

Product Description

DGL - Deglycyrrhizinated Licorice Root, Chewable

AOR DGL Licorice Root

Deglycyrrhizinated licorice (DGL) root extract in a chewable, lemon-flavoured tablet. Used in Herbal Medicine to help relieve abdominal pain and burning sensation in the stomach (demulcent) and minor inflammations of the gastrointestinal tract - without the glycyrrhizin fraction that gives standard licorice root its cautions. Licensed Natural Health Product NPN 80134241.

Extrait de racine de réglisse déglycyrrhizinée (DGL) en comprimé à croquer, aromatisé au citron. Utilisé en phytothérapie pour aider à soulager la douleur abdominale et la sensation de brûlure à l'estomac (démulcent) et les inflammations mineures du tractus gastro-intestinal - sans la fraction d'acide glycyrrhizique qui justifie les mises en garde de la réglisse standard. Produit de santé naturel homologué. NPN 80134241.

DGL Licorice Root lifestyle
AOR DGL Licorice Root
Premium - AOR

Chewable DGL, Lemon Flavour

506.66 mg deglycyrrhizinated licorice extract per tablet - Vegan, Non-GMO, Gluten-Free

Deglycyrrhizinated for a Milder Profile

Processing reduces the glycyrrhizin naturally found in licorice root to no more than 3% of its original amount (Health Canada's DGL specification) - the fraction linked to standard licorice's cautions.

Chew, Don't Swallow Whole

A chewable, lemon-flavoured tablet - chewed between meals or 20 minutes before meals so the extract mixes with saliva, exactly as intended for this ingredient.

What AOR DGL Supports

Four ways this deglycyrrhizinated licorice chewable supports digestive comfort.

Digestive Comfort

Helps relieve abdominal pain and burning sensation in the stomach (demulcent action).

Gastrointestinal Health

Helps relieve minor inflammations of the gastrointestinal tract.

Gastric Mucosal Support

Traditionally used to support the stomach's own protective mucus lining.

Milder By Design

Deglycyrrhizinated so you get licorice's traditional digestive use without the glycyrrhizin cautions of standard licorice root.

AOR DGL Licorice Root: Supplement Facts

AOR™DGL Licorice Root
English

Each Chewable Tablet contains:

  • Deglycyrrhizinated licorice root extract (Glycyrrhiza glabra) Extract 5.921:1 (3000 mg dried herb equivalent)506.66 mg

Non-Medicinal Ingredients: Hydroxypropyl cellulose, xylitol, tapioca syrup, distilled water, citric acid anhydrous, monk fruit extract, natural lemon flavor, maltodextrin (corn), dextrose, acacia gum, tricalcium phosphate, sodium stearyl fumarate.

Recommended Use or Purpose: Used in Herbal Medicine to help relieve abdominal pain and burning sensation in the stomach (demulcent). Used in Herbal Medicine to help relieve minor inflammations of the gastrointestinal tract.

Recommended Dose (Adults 18 years and older): Chew 1 tablet 3 times per day, between meals or 20 minutes before meals. Do not exceed the recommended daily dose unless directed by a health care practitioner. Recommended Duration of Use: Health Canada's monograph for this ingredient does not require a duration-of-use statement.

Cautions and Warnings: Ask a health care practitioner if symptoms persist or worsen. Allergen: This product contains corn; do not use if you have corn allergies. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings and directions before using or consuming a product. Other Information: GMP Manufacturing, Independent Testing, Quality Assured. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.

Français

Chaque comprimé à croquer contient :

  • Extrait de racine de réglisse déglycyrrhizinée (Glycyrrhiza glabra) Extrait 5,921:1 (3000 mg d'équivalent en plante séchée)506.66 mg

Ingrédients non médicinaux : Hydroxypropylcellulose, xylitol, sirop de tapioca, eau distillée, acide citrique anhydre, extrait de fruit du moine, saveur naturelle de citron, maltodextrine (maïs), dextrose, gomme d'acacia, phosphate tricalcique, stéarylfumarate de sodium.

Usage ou fins recommandés : Utilisé en phytothérapie pour aider à soulager la douleur abdominale et la sensation de brûlure à l'estomac (démulcent). Utilisé en phytothérapie pour aider à soulager les inflammations mineures du tractus gastro-intestinal.

Dose recommandée (adultes de 18 ans et plus) : Croquer 1 comprimé 3 fois par jour, entre les repas ou 20 minutes avant les repas. Ne pas dépasser la dose quotidienne recommandée sauf indication contraire d'un professionnel de la santé. Durée d'utilisation recommandée : la monographie de Santé Canada pour cet ingrédient n'exige aucun énoncé sur la durée d'utilisation.

Mises en garde : Consulter un professionnel de la santé si les symptômes persistent ou s'aggravent. Allergène : ce produit contient des allergènes de maïs; ne pas utiliser si vous avez des allergies. Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement fermé dans un endroit frais et sec.

NPN 80134241

506.66 mg Deglycyrrhizinated Licorice (DGL)90 chewable tablets - up to a 1-month supplyVegan - Non-GMO - Gluten-FreeMade in Canada

Add AOR DGL to your daily routine

Get AOR DGL on Amazon.ca - fast, protected delivery.

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Why AOR DGL

A deglycyrrhizinated licorice root chewable, made to support digestive comfort without the cautions of standard licorice.

Deglycyrrhizinated for a milder profile

Processing reduces the glycyrrhizin fraction, so Health Canada's DGL monograph lists no contraindications, no duration-of-use limit and no known adverse reactions.

Chewable, saliva-activated format

Chewed between meals or 20 minutes before meals - exactly how Health Canada's monograph specifies this ingredient should be used to mix with saliva.

Vegan, lemon-flavoured, single ingredient

90 chewable tablets with a natural lemon flavour - vegan, non-GMO and gluten-free, with no capsule to swallow.

Premium Canadian brand

AOR - Advanced Orthomolecular Research, since 1991. NPN 80134241.

How to use it

Chew 1 tablet, 3 times a day

Adults chew 1 tablet 3 times per day - this is a chewable tablet, meant to be chewed and mixed with saliva, not swallowed whole like a capsule.

Time it around meals

Chew between meals or about 20 minutes before meals, or as directed by a health care practitioner.

Do not exceed the daily dose

Do not exceed the recommended daily dose unless instructed by a health care practitioner.

What the research says about deglycyrrhizinated licorice (DGL)

Educational summaries of published research on deglycyrrhizinated licorice (DGL) and licorice (Glycyrrhiza glabra); not product-specific claims. AOR DGL's claim is the traditional/authorized use under NPN 80134241.

Gastric Mucosal Protection Mechanism

Stimulates mucus-secreting stomach cells

In rats, deglycyrrhizinated liquorice (DGL) increased the number and activity of mucus-secreting cells in the stomach lining, supporting a mucus-mediated mechanism behind its traditional demulcent use.

Animal study
van Marle et al., European Journal of Pharmacology (1981)
Gastric Mucosal Protection Mechanism

Protected the stomach lining against aspirin damage

In rats, DGL reduced gastric mucosal injury caused by aspirin and aspirin-plus-bile-acid, including a protective effect seen even when DGL was given systemically rather than just locally.

Animal study
Russell, Morgan & Nelson, Scandinavian Journal of Gastroenterology. Supplement (1984)
Gastric Mucosal Protection Mechanism

Licorice among plants that reinforce the mucosal barrier

A review of medicinal plants used for peptic ulcers highlighted licorice among botanicals whose gastroprotective mechanisms include strengthening the gastric mucosal barrier and reducing acid-related irritation.

Review
Cherrada et al., Food Science & Nutrition (2024)
Digestive Comfort & Reflux Research

A modern DGL extract improved reflux symptoms in a placebo trial

A randomized, double-blind, placebo-controlled trial of a standardized deglycyrrhizinated licorice extract reported better quality-of-life scores and earlier relief of heartburn and regurgitation over 28 days than placebo.

Human RCT
Raj et al., Complementary Medicine Research (2025)
Digestive Comfort & Reflux Research

A licorice-containing chewing gum eased heartburn after a trigger meal

In a placebo-controlled crossover trial, a chewing gum blending licorice extract with calcium carbonate, papain and apple cider vinegar lowered heartburn and acid-reflux ratings after a reflux-provoking meal.

Human RCT
Brown et al., Journal of Dietary Supplements (2014)
Digestive Comfort & Reflux Research

Licorice reviewed among popular remedies for reflux

A critical appraisal of complementary remedies for esophageal symptoms discussed licorice alongside melatonin, slippery elm and peppermint oil, noting real interest but calling for more rigorous research.

Review
Ahuja & Ahuja, Current Gastroenterology Reports (2019)
Why Deglycyrrhizinated: Comparative Safety

Even low-dose standard licorice raised blood pressure

A randomized crossover trial found that just 100 mg/day of glycyrrhizic acid from regular licorice significantly raised home blood pressure and suppressed renin and aldosterone in healthy adults over two weeks.

Human RCT
af Geijerstam et al., American Journal of Clinical Nutrition (2024)
Why Deglycyrrhizinated: Comparative Safety

Why standard licorice carries real cautions

A clinical review of licorice's adverse effects explains how glycyrrhizin's metabolites can trigger apparent mineralocorticoid excess syndrome - hypertension, fluid retention and low potassium - the exact risk profile that deglycyrrhizination is designed to avoid.

Review
Care et al., La Revue de Medecine Interne (2023)
Why Deglycyrrhizinated: Comparative Safety

The sodium-retention problem that predates DGL

An early clinical trial of carbenoxolone, a glycyrrhetinic-acid-derived ulcer drug, documented sodium and fluid retention side effects - part of the historical rationale for developing a glycyrrhizin-free (deglycyrrhizinated) form of licorice.

Clinical trial
Turpie & Thomson, Gut (1965)
DGL Safety & Tolerability

DGL tablets well tolerated in a 32-patient survey

A retrospective endoscopic survey of 32 patients using deglycyrrhizinized liquorice tablets for chronic duodenal ulcer found healing with good tolerability, and noted the preparation worked best when well chewed on an empty stomach.

Clinical survey
Larkworthy & Holgate, The Practitioner (1975)
DGL Safety & Tolerability

Fast, well-tolerated relief for mouth ulcers

In a small study, a deglycyrrhizinated licorice mouth rinse was well tolerated and most of the 20 patients with aphthous mouth ulcers reported 50-75% improvement within a day, with complete healing by the third day.

Case series
Das et al., Journal of the Association of Physicians of India (1989)
DGL Safety & Tolerability

Identifying the metabolites behind licorice's side effects

Researchers identified the specific glycyrrhetinic-acid metabolites of glycyrrhizin responsible for licorice's mineralocorticoid-like effects and their individual variability - the same metabolites that deglycyrrhizination is intended to remove.

Human study
Sakoda et al., Drug Metabolism and Disposition (2024)
Mucosal Healing: Clinical Evidence

A controlled trial of DGL in gastric ulcer

A controlled clinical trial of deglycyrrhizinized liquorice in patients with gastric ulcer is among the classic studies establishing DGL as a subject of formal ulcer research in the 1960s.

Controlled clinical trial
Turpie, Runcie & Thomson, Gut (1969)
Mucosal Healing: Clinical Evidence

Early evidence of a muscle-relaxant (spasmolytic) effect

A controlled study of DGL in gastric and duodenal ulcer patients specifically examined a spasmolytic (smooth-muscle relaxant) effect alongside ulcer healing outcomes.

Controlled clinical trial
Tewari & Trembalowicz, Gut (1968)
Mucosal Healing: Clinical Evidence

Documented in the British Medical Journal

A clinical report on deglycyrrhizinized liquorice in duodenal ulcer was among the early findings published in the British Medical Journal documenting clinical interest in DGL as an ulcer therapy.

Clinical report
Whiting & Thomson, British Medical Journal (1971)
Licorice Phytochemistry Foundations

Decades of licorice pharmacology reviewed

An updated review of Glycyrrhiza species summarized wide-ranging pharmacological properties - including gastroprotective, anti-inflammatory and antioxidant effects - and the phytochemistry behind them.

Review
Hosseinzadeh & Nassiri-Asl, Phytotherapy Research (2015)
Licorice Phytochemistry Foundations

A comprehensive look at licorice's active compounds

A comprehensive review traced licorice's phytochemistry, biological activities and toxicology, highlighting flavonoids such as liquiritigenin, isoliquiritigenin and glabridin alongside glycyrrhizin.

Comprehensive review
Wahab et al., Plants (2021)
Licorice Phytochemistry Foundations

Mapping the Glycyrrhiza genus's bioactive molecules

A review of the Glycyrrhiza genus catalogued its rich pool of bioactive molecules - triterpene saponins like glycyrrhizin and flavonoids like liquiritigenin and liquiritin - and their antioxidant and anti-inflammatory activities.

Review
Sharifi-Rad et al., Oxidative Medicine and Cellular Longevity (2021)
Historical & Traditional Use

A 1978 double-blind trial of DGL

A double-blind clinical trial evaluated deglycyrrhizinated liquorice for chronic duodenal ulcer, part of a wave of controlled studies on DGL published through the 1970s.

Human RCT
Balakrishnan et al., Journal of the Association of Physicians of India (1978)
Historical & Traditional Use

DGL compared head-to-head with an early acid-blocking drug

A randomized trial compared deglycyrrhizinized liquorice with cimetidine (an early histamine H2-receptor blocker) in duodenal and gastric ulcer patients, reflecting DGL's place among the ulcer treatments of its era.

Human RCT
D'Imperio et al., Acta Gastro-Enterologica Belgica (1978)
Historical & Traditional Use

Not every historical trial found a benefit

A double-blind, placebo-controlled trial of DGL (as Caved-S) in 47 patients with active duodenal ulcer found no significant advantage over placebo after one month - a reminder that the historical DGL evidence base is mixed, not uniformly positive.

Human RCT
Feldman & Gilat, Gut (1971)
Digestive Comfort & Everyday Habits

Why chewing (not swallowing) may matter

In healthy volunteers, chewing gum doubled salivary flow and markedly shortened how long it took the esophagus to clear infused acid, illustrating why a chewed, saliva-stimulating format can support esophageal comfort.

Human study
von Schonfeld et al., Digestion (1997)
Digestive Comfort & Everyday Habits

Lifestyle and diet shape reflux symptoms

A review of modifiable risk factors for gastroesophageal reflux found body weight, alcohol, smoking, irregular meal patterns and large or late meals were consistently linked to symptoms, alongside common trigger foods.

Review
Taraszewska, Roczniki Panstwowego Zakladu Higieny (2021)
Digestive Comfort & Everyday Habits

Diet and lifestyle changes can meaningfully ease reflux

A 2025 review of non-drug approaches to reflux found low-carbohydrate eating, trigger-food elimination and weight management each produced measurable symptom improvement, with some patients discontinuing medication.

Review
Bertin, Caldart & Savarino, Best Practice & Research Clinical Gastroenterology (2025)

Frequently asked questions

What is DGL and how is it different from regular licorice?

DGL stands for deglycyrrhizinated licorice - licorice root (Glycyrrhiza glabra) that has had most of its glycyrrhizin removed during processing. Health Canada requires a DGL finished product to contain no more than 3% of the glycyrrhizic acid originally found in the source material, which is why DGL does not carry the same cautions as standard licorice.

How do I take AOR DGL?

Adults chew 1 tablet 3 times per day, between meals or about 20 minutes before meals, or as directed by a health care practitioner. Do not exceed the recommended daily dose.

Do I need to chew it, or can I swallow it like a capsule?

Chew it. AOR DGL is a chewable tablet, not a capsule - Health Canada's monograph for this ingredient specifies chewable forms so the extract mixes with saliva.

What does it taste like?

AOR DGL is lemon flavoured and sweetened with xylitol and monk fruit extract.

Is it vegan and allergen-friendly?

It is vegan, non-GMO and gluten-free. It does contain corn (in the maltodextrin), so it is not corn-free - check the ingredient list if you have a corn allergy.

Is DGL safe for long-term or frequent use?

Health Canada's monograph for deglycyrrhizinated licorice does not require a duration-of-use statement, and its only listed caution is to ask a health care practitioner if symptoms persist or worsen. As with any natural health product, discuss long-term use with a health care practitioner for your specific situation.

How is this different from standard licorice root supplements?

Standard licorice root contains glycyrrhizin, which research links to raised blood pressure and lowered potassium with regular use. AOR DGL has had that fraction reduced during processing specifically to avoid those effects, under Health Canada's separate deglycyrrhizinated-licorice monograph.

Where do I buy it, and is it made in Canada?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca. AOR (Advanced Orthomolecular Research) is based in Calgary, Alberta, and is licensed by Health Canada under NPN 80134241.

506.66 mg Deglycyrrhizinated Licorice (DGL)90 chewable tablets - up to a 1-month supplyVegan - Non-GMO - Gluten-FreeMade in Canada

Add AOR DGL to your daily routine

Get AOR DGL on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80134241. Deglycyrrhizinated licorice (DGL) is used in Herbal Medicine to help relieve abdominal pain and burning sensation in the stomach and minor inflammations of the gastrointestinal tract. The research summaries below concern deglycyrrhizinated licorice and licorice (Glycyrrhiza glabra) generally and are educational - they are not product-specific claims. Read and follow the label. Ask a health care practitioner if symptoms persist or worsen. Results may vary.

Important information

Safety Information

Cautions and Warnings: Ask a health care practitioner if symptoms persist or worsen. Allergen: This product contains corn; do not use if you have corn allergies. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place.

Indications

Recommended Use or Purpose: Used in Herbal Medicine to help relieve abdominal pain and burning sensation in the stomach (demulcent). Used in Herbal Medicine to help relieve minor inflammations of the gastrointestinal tract.

Ingredients

Medicinal Ingredient (per 1 chewable tablet): Deglycyrrhizinated licorice root extract (Glycyrrhiza glabra), Extract 5.921:1 (3000 mg dried herb equivalent) - 506.66 mg. Non-medicinal Ingredients: Hydroxypropyl cellulose, xylitol, tapioca syrup, distilled water, citric acid anhydrous, monk fruit extract, natural lemon flavor, maltodextrin (corn), dextrose, acacia gum, tricalcium phosphate, sodium stearyl fumarate. Health Canada's Deglycyrrhizinated Licorice monograph requires the finished product to contain no more than 3% of the original glycyrrhizic acid found in the source material.

Directions

Recommended Dose (Adults 18 years and older): Chew 1 tablet 3 times per day, between meals or 20 minutes before meals. Do not exceed the recommended daily dose unless directed by a health care practitioner. Recommended Duration of Use: Health Canada's monograph for this ingredient does not require a duration-of-use statement.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings and directions before using or consuming a product. Other Information: GMP Manufacturing, Independent Testing, Quality Assured. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.