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Health Canada NPN 80128875 L-Lysine 1000 mg per daily serving Dairy-free - Gluten-free - Yeast-free Made in Canada - GMP facility
Natra LYSINEprotect - Cold Sore L-Lysine Supplement | 60 Capsules Natra LYSINEprotect - Cold Sore L-Lysine Supplement | 60 Capsules benefits and key ingredients Natra LYSINEprotect - Cold Sore L-Lysine Supplement | 60 Capsules lifestyle Natra LYSINEprotect - Cold Sore L-Lysine Supplement | 60 Capsules ingredients Natra LYSINEprotect - Cold Sore L-Lysine Supplement | 60 Capsules supplement facts

Natra LYSINEprotect - Cold Sore L-Lysine Supplement | 60 Capsules

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$48.88 CAD ($0.81 / capsule)
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BrandNatra
Serving2 vegetarian capsules, once daily
Licensed Natural Health ProductNPN 80128875
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • LYSINE 500 MG, DAILY ORAL CAPSULE: An L-Lysine 500 mg supplement in vegetarian capsule form - not a cream or patch. Helps to reduce the recurrence of herpes simplex virus (HSV) infections, such as cold sores, for proactive daily support.
  • WHY A LYSINE SUPPLEMENT vs A TOPICAL: A daily oral capsule for people who want ongoing internal L-Lysine support, not a spot-treat cream or patch. Take 2 capsules once daily - a simple 30-day routine of 60 capsules.
  • 8 INGREDIENTS IN ONE FORMULA: Combines L-Lysine, Andrographis, Olive Leaf, Prunella, Zinc, Vitamin C, Vitamin B6 (P5P) and Selenium to help maintain and support immune function and overall wellness in a single daily serving.
  • HOW TO USE + ALLERGENS: Adults take 2 capsules once daily with food. Dairy-free, gluten-free and yeast-free; no artificial colours or preservatives. Consult a health practitioner before use if pregnant, breastfeeding, or on medication. Verify full allergens on the label.
  • CLEAN CANADIAN QUALITY YOU CAN TRUST: Made in Canada in a GMP-compliant facility. Licensed Natural Health Product, NPN 80128875. Vegetarian V-Capsules with no artificial colours or preservatives - quality you can read on the label.
  • L-LYSINE + IMMUNE MINERALS: Each daily serving pairs L-Lysine 500 mg with Zinc, Selenium, Vitamin C and Vitamin B6 (P5P), nutrients that help maintain and support immune function during seasonal changes.
  • PRUNELLA + OLIVE LEAF + ANDROGRAPHIS BOTANICALS: Includes Prunella vulgaris, plus Olive Leaf standardized to 15% oleuropein for antioxidant support and Andrographis paniculata - traditional botanicals rounding out this lysine-based daily immune formula.
  • EASY-TO-TAKE VEGETARIAN CAPSULES: 60 vegetarian V-Capsules, swallowed - no measuring powders, no mess. One bottle is a 30-day supply at 2 capsules per day, made for adults who deal with recurring cold sores.

Product description

Natra LYSINEprotect - a daily oral lysine routine for recurring cold sores

Natra LYSINEprotect

A closer look at Natra LYSINEprotect - L-Lysine 1000 mg per serving with immune botanicals and minerals, made in Canada. Licensed Natural Health Product NPN 80128875.

LYSINEprotect lifestyle
Natra LYSINEprotect
Premium Quality

LYSINEprotect

LYSINE 500 MG, DAILY ORAL CAPSULE

An L-Lysine 500 mg supplement in vegetarian capsule form - not a cream or patch. Helps to reduce the recurrence of herpes simplex virus (HSV) infections, such as cold sores, for proactive daily support.

WHY A LYSINE SUPPLEMENT vs A TOPICAL

A daily oral capsule for people who want ongoing internal L-Lysine support, not a spot-treat cream or patch. Take 2 capsules once daily - a simple 30-day routine of 60 capsules.

Advanced Ingredients, Superior Results

A closer look at Natra LYSINEprotect - L-Lysine 1000 mg per serving with immune botanicals and minerals, made in Canada.

L-Lysine

1000 mg / serving

Olive Leaf

15% oleuropein

Prunella

self-heal herb

Andrographis

paniculata

Vitamin C

Mg ascorbate

Zinc

bisglycinate

Vitamin B6

P5P

Selenium

selenomethionine

Natra LYSINEprotect: Supplement Facts

Natra™LYSINEprotect
English

Each Capsule contains:

  • L-Lysine500 mg
  • Prunella (Self-heal herb) (Prunella vulgaris, Shoot and leaf, 10:1 extract equivalent to 375 mg of dry herb)37.5 mg
  • Olive leaf (Olea europaea, Leaf, 10.9:1 extract equivalent to 300 mg of dry herb) Standardized to contain 15.0% Oleuropein27.5 mg
  • Andrographis (Andrographis paniculata, Herb top, 4:1 extract equivalent to 100 mg of dry herb)25 mg
  • Vitamin C (Magnesium ascorbate)25 mg
  • Vitamin B6 (Pyridoxal 5'-phosphate)7.5 mg
  • Zinc (Zinc bisglycinate)1 mg
  • Selenium (Selenomethionine)37.5 mcg

Non-Medicinal Ingredients: Hypromellose, Microcrystalline cellulose, Stearic acid, Silicon dioxide.

Recommended Use or Purpose: Recommended Purpose: Helps to reduce the recurrence of herpes simplex virus (HSV) infection (e.g. cold sores). Source of an essential amino acid involved in muscle protein synthesis and the maintenance of good health. Helps in energy metabolism and tissue formation. Helps to maintain immune function and the immune system. Source of vitamins and minerals to support biological functions which play a key role in the maintenance of good health.

Recommended Dose: Recommended Dose (Adults 19 years and older): Take 2 capsules, 1 time per day. Take with food, a few hours before or after taking other medications or natural health products. Recommended Duration of Use: Consult a health care practitioner for prolonged use.

Cautions and Warnings: Cautions and Warnings: Consult a health care practitioner prior to use: if you are taking prescription medications; if you have serious or major conditions, any type of acute infection, deficiency or excess; if you are taking other diuretics; if you have a history of non-melanoma skin cancer; if you have a kidney disorder. Stop use and consult a health care practitioner if symptoms persist or worsen, or if new symptoms develop. Contra-Indications: Do not use this product if you are pregnant or breastfeeding. Known Adverse Reactions: Diuretic effect may occur. Zinc supplementation can cause a copper deficiency. If you are unsure whether you are taking enough copper, consult a health care practitioner prior to use. Sealed for your protection. Store in a cool dark place. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Chaque capsule contient :

  • L-lysine500 mg
  • Brunelle commune (auto-guérison) (Prunella vulgaris, pousse et feuille, extrait 10:1 équivalant à 375 mg de plante sèche)37.5 mg
  • Feuille d'olivier (Olea europaea, feuille, extrait 10,9:1 équivalant à 300 mg de plante sèche) Normalisé pour contenir 15,0 % d'oleuropéine27.5 mg
  • Andrographis (Andrographis paniculata, parties aériennes, extrait 4:1 équivalant à 100 mg de plante sèche)25 mg
  • Vitamine C (ascorbate de magnésium)25 mg
  • Vitamine B6 (pyridoxal 5'-phosphate)7.5 mg
  • Zinc (bisglycinate de zinc)1 mg
  • Sélénium (sélénométhionine)37.5 mcg

Ingrédients non médicinaux : hypromellose, cellulose microcristalline, acide stéarique, dioxyde de silicium.

NPN 80128875

L-Lysine 1000 mg per serving8 actives - lysine, botanicals & immune mineralsDairy-free - Gluten-free - Yeast-freeMade in Canada - 60 V-Capsules

A simple daily oral lysine routine for recurring cold sores

Get Natra LYSINEprotect on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why Natra LYSINEprotect

L-Lysine plus a focused blend of immune botanicals and minerals.

Cold Sore Support

L-Lysine helps to reduce the recurrence of herpes simplex virus (HSV) infections, such as cold sores - the authorized purpose of this product.

Immune Function

Vitamin C, zinc, selenium and vitamin B6 are nutrients that help to maintain and support immune function and the immune system.

Botanical Blend

Olive leaf (15% oleuropein), prunella and andrographis round out the formula alongside the L-Lysine core.

Daily Oral Routine

A swallowed vegetarian capsule, not a cream or patch - 2 capsules once daily for ongoing internal support.

Inside every serving

L-Lysine 1000 mg per 2-capsule serving, paired with olive leaf, prunella, andrographis, vitamin C, B6, zinc and selenium.

L-Lysine 1000 mg / servingOlive Leaf 15% oleuropeinPrunella self-heal herbAndrographis paniculataVitamin C Mg ascorbateZinc bisglycinateVitamin B6 P5PSelenium selenomethionine

How Natra compares

Why a daily oral lysine formula with immune support matters.

 Natra LYSINEprotectTopical creamsPlain lysine tablets
FormatDaily oral V-CapsuleSpot-treat cream / patchOral tablet
L-Lysine per serving1000 mgNone (topical)Varies
Immune mineralsZinc, selenium, vitamin C, B6NoneUsually none
Botanical supportOlive leaf, prunella, andrographisNoneNone
SourcingMade in Canada - GMP Made in CanadaVariesVaries
Allergen profileDairy-free, gluten-free, yeast-freeVariesVaries

How to use

Take 2 capsules

Adults 19 years and older: take 2 vegetarian capsules, 1 time per day.

Take with food

Take with food, a few hours before or after other medications or natural health products.

Keep it daily

Use consistently as a daily routine; one bottle of 60 capsules is a 30-day supply.

Check with your practitioner

Consult a health-care practitioner for prolonged use, or before use if you have any listed condition.

What the research says about the active ingredients

Peer-reviewed studies and reviews on the individual actives in this formula - L-lysine, olive leaf (oleuropein), Prunella vulgaris, Andrographis paniculata, zinc and vitamin C - shared for education, not as claims about this finished product. Natra LYSINEprotect's claims are the statements authorized under its Natural Health Product licence, NPN 80128875.

L-Lysine & HSV

Fewer recurrences in a controlled trial

A double-blind, placebo-controlled multicentre trial of oral L-lysine (1000 mg, three times daily for six months) reported that the lysine group averaged significantly fewer herpes simplex recurrences, with reduced symptom severity and healing time.

Human RCT
Griffith et al., Dermatologica (1987)
L-Lysine & HSV

More patients stayed recurrence-free

In a double-blind, placebo-controlled crossover study (1000 mg daily), significantly more patients were recurrence-free during lysine than during placebo, suggesting some people may benefit from prophylactic lysine.

Human RCT
Milman et al., Acta Dermato-Venereologica (1980)
L-Lysine & HSV

Evidence is mixed - one trial found no benefit

A double-blind, placebo-controlled trial using a lower dose (400 mg, three times daily) detected no substantial benefit on episode frequency, duration or severity, underlining that the evidence for lysine is mixed.

Human RCT
DiGiovanna & Blank, Archives of Dermatology (1984)
L-Lysine in context

Inhibits HSV multiplication in cell culture

Authors note that L-lysine has an inhibitory effect on the multiplication of herpes simplex virus in cell cultures, the rationale behind testing it as an oral prophylactic in people.

Cell-culture rationale
Milman et al., Acta Dermato-Venereologica (1980)
L-Lysine in context

Cochrane review of cold-sore prevention

A Cochrane systematic review of interventions to prevent herpes labialis catalogued the range of preventive options studied and assessed the strength of the underlying evidence.

Systematic review
Chi et al., Cochrane Database of Systematic Reviews (2015)
L-Lysine in context

Treatment and prophylaxis both studied

Across trials, oral L-lysine has been evaluated both for treating active episodes and as ongoing prophylaxis, with effects on occurrence, severity and healing time reported in the positive trials.

Human RCT
Griffith et al., Dermatologica (1987)
Olive Leaf & Oleuropein

Oleuropein inhibits HSV-1 in cells

In a cell-based study, subtoxic concentrations of oleuropein - the olive leaf compound this formula is standardized to - inhibited herpes simplex virus type 1 replication, with effects linked to host antiviral signalling proteins.

Lab study
Pennisi et al., Biomolecules (2023)
Olive Leaf & Oleuropein

Antioxidant protection from olive leaf

The same study found olive leaf extracts protected human cells from lipid peroxidation after oxidative stress and raised antioxidant enzymes such as catalase and superoxide dismutase.

Lab study
Pennisi et al., Biomolecules (2023)
Olive Leaf & Oleuropein

Olive leaf's broader actions reviewed

A review notes olive leaf is rich in oleuropein and hydroxytyrosol and summarizes reported anti-inflammatory, immunomodulatory and antiviral activities of the leaf and its phenolics.

Review
Abdelgawad et al., Frontiers in Pharmacology (2022)
Prunella & Andrographis

Prunella vulgaris is virucidal to HSV

An anti-HSV polysaccharide isolated from Prunella vulgaris abolished the infectivity of HSV-1 in a plaque assay and was active against acyclovir-resistant strains, with a mode of action differing from acyclovir.

Lab study
Xu et al., Antiviral Research (1999)
Prunella & Andrographis

Andrographis for respiratory symptoms

A systematic review of seven double-blind controlled trials (896 participants) concluded Andrographis paniculata is superior to placebo for relieving symptoms of uncomplicated upper respiratory tract infection, with mild, infrequent adverse events.

Systematic review
Coon & Ernst, Planta Medica (2004)
Prunella & Andrographis

Andrographis in a randomized trial

A double-blind, placebo-controlled trial (158 adults, 1200 mg/day) reported a significant reduction in the intensity of common-cold symptoms such as sore throat and nasal secretion versus placebo, with no adverse effects reported.

Human RCT
Caceres et al., Phytomedicine (1999)
Zinc & Immunity

A gatekeeper of immune function

A review describes zinc as essential for innate and adaptive immune cells, with zinc ions regulating intracellular signalling and a pro-inflammatory phenotype developing during zinc deficiency.

Review
Wessels et al., Nutrients (2017)
Zinc & Immunity

Needed across immune cell types

A comprehensive review summarizes zinc's role in haematopoiesis and in the activation and function of immune cells against bacteria, parasites and viruses, supporting why deficiency impairs defence.

Review
Wessels et al., Annual Review of Nutrition (2021)
Zinc & Immunity

Deficiency impairs, repletion restores

A review notes that all immune cell types show decreased function under zinc depletion and that impaired functions can be reversed by adequate zinc supplementation matched to need.

Review
Ibs & Rink, Journal of Nutrition (2003)
Zinc & Colds

Shorter colds in a Cochrane review

A Cochrane meta-analysis found zinc taken within 24 hours of onset significantly reduced the duration of common-cold symptoms in healthy people, though heterogeneity warrants caution.

Meta-analysis
Singh & Das, Cochrane Database of Systematic Reviews (2013)
Zinc & Colds

Zinc acetate lozenges cut cold duration

An individual-patient-data meta-analysis of three randomized trials estimated zinc acetate lozenges shortened colds by roughly 2.7 days versus a 7-day average, consistently across patient subgroups.

Meta-analysis
Hemila et al., British Journal of Clinical Pharmacology (2016)
Zinc & Colds

Lower cold incidence with supplementation

In the Cochrane review, longer-term zinc supplementation was associated with lower cold incidence and fewer related school absences in children.

Meta-analysis
Singh & Das, Cochrane Database of Systematic Reviews (2013)
Vitamin C

Shorter colds with regular intake

A Cochrane meta-analysis of regular vitamin C supplementation found a consistent reduction in common-cold duration - about 8% in adults and 14% in children - though it did not reduce incidence in the general population.

Meta-analysis
Hemila & Chalker, Cochrane Database of Systematic Reviews (2013)
Vitamin C

Supports immune cell measures

A meta-analysis of high-dose vitamin C reported increased lymphocyte counts and reduced markers of inflammation, consistent with vitamin C's role in supporting immune-cell function.

Meta-analysis
Sun et al., Nutrition Reviews (2024)
Vitamin C

A role across immune defences

A review details how vitamin C supports immune-cell function and helps reduce oxidative stress, part of why adequate status matters for resistance to infection.

Review
Wang et al., European Journal of Medical Research (2023)
Micronutrients

Several nutrients underpin immunity

A review highlights that vitamin C, zinc, selenium and vitamin D each support the adaptive and innate immune systems, so suboptimal status of these immune-relevant micronutrients can impair immune function.

Review
Grober & Holick, International Journal for Vitamin and Nutrition Research (2021)
Micronutrients

Correct deficiencies to support defence

The same review argues that immune-relevant micronutrient deficiencies should be corrected to help maintain physiological resilience to infection, especially in vulnerable groups.

Review
Grober & Holick, International Journal for Vitamin and Nutrition Research (2021)
Micronutrients

Zinc and the immune signalling system

Mechanistic reviews link zinc homeostasis to the regulation of key immune signalling molecules, illustrating how a trace mineral influences whole-body immune responses.

Review
Wessels et al., Nutrients (2017)

Frequently asked questions

What is Natra LYSINEprotect for?

It is a daily oral L-Lysine supplement that helps to reduce the recurrence of herpes simplex virus (HSV) infections, such as cold sores, and helps to maintain immune function. It is a swallowed capsule, not a cream or patch.

How do I take it?

Adults 19 years and older take 2 vegetarian capsules once daily, with food, a few hours before or after other medications or natural health products. Consult a health-care practitioner for prolonged use.

How much L-Lysine is in each serving?

Each 2-capsule daily serving provides 1000 mg of L-Lysine (500 mg per capsule), alongside olive leaf, prunella, andrographis, vitamin C, vitamin B6, zinc and selenium.

What else is in the formula?

Beyond L-Lysine, each serving includes Olive Leaf (standardized to 15% oleuropein), Prunella vulgaris, Andrographis paniculata, Vitamin C (magnesium ascorbate), Vitamin B6 (P5P), Zinc (bisglycinate) and Selenium (selenomethionine).

How long does one bottle last?

Each bottle has 60 vegetarian V-Capsules - a 30-day supply at 2 capsules per day.

Is it made in Canada?

Yes. It is manufactured in Canada in a GMP-compliant facility and licensed by Health Canada under NPN 80128875.

Are there any allergens or cautions?

It is dairy-free, gluten-free and yeast-free with no artificial colours or preservatives. Do not use if pregnant or breastfeeding. Consult a practitioner prior to use if you take prescription medications or diuretics, have a kidney disorder, or a history of non-melanoma skin cancer. Zinc supplementation can cause a copper deficiency.

Where do I buy it?

Use the orange button on this page - it takes you to the Natra listing on Amazon.ca for secure checkout and fast delivery.

L-Lysine 1000 mg per serving8 actives - lysine, botanicals & immune mineralsDairy-free - Gluten-free - Yeast-freeMade in Canada - 60 V-Capsules

A simple daily oral lysine routine for recurring cold sores

Get Natra LYSINEprotect on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80128875. Natra LYSINEprotect helps to reduce the recurrence of herpes simplex virus (HSV) infection (e.g. cold sores) and helps to maintain immune function. The research summaries below concern the individual active ingredients in this formula (L-lysine, olive leaf, Prunella vulgaris, Andrographis paniculata, zinc and vitamin C) and are educational - they are not claims about this finished product. Read and follow the label. Consult a health-care practitioner prior to use if you are taking prescription medications, if you have a kidney disorder, a history of non-melanoma skin cancer, or are taking other diuretics. Do not use if you are pregnant or breastfeeding. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner prior to use: if you are taking prescription medications; if you have serious or major conditions, any type of acute infection, deficiency or excess; if you are taking other diuretics; if you have a history of non-melanoma skin cancer; if you have a kidney disorder. Stop use and consult a health care practitioner if symptoms persist or worsen, or if new symptoms develop. Contra-Indications: Do not use this product if you are pregnant or breastfeeding. Known Adverse Reactions: Diuretic effect may occur. Zinc supplementation can cause a copper deficiency. If you are unsure whether you are taking enough copper, consult a health care practitioner prior to use. Sealed for your protection. Store in a cool dark place. Keep out of reach of children.

Indications

Recommended Purpose: Helps to reduce the recurrence of herpes simplex virus (HSV) infection (e.g. cold sores). Source of an essential amino acid involved in muscle protein synthesis and the maintenance of good health. Helps in energy metabolism and tissue formation. Helps to maintain immune function and the immune system. Source of vitamins and minerals to support biological functions which play a key role in the maintenance of good health.

Ingredients

Medicinal ingredients (per 2 capsules): L-Lysine 1000 mg; Prunella (Prunella vulgaris, Self-heal herb, shoot and leaf, 10:1 extract equivalent to 375 mg dry herb) 75 mg; Olive leaf (Olea europaea, 10.9:1 extract equivalent to 300 mg dry herb, standardized to 15.0% oleuropein) 55 mg; Andrographis (Andrographis paniculata, herb top, 4:1 extract equivalent to 100 mg dry herb) 50 mg; Vitamin C (magnesium ascorbate) 50 mg; Vitamin B6 (pyridoxal 5-phosphate) 15 mg; Zinc (zinc bisglycinate) 2 mg; Selenium (selenomethionine) 75 mcg. Non-medicinal ingredients: Hypromellose, microcrystalline cellulose, stearic acid, silicon dioxide. Dairy-free, gluten-free and yeast-free; no artificial colours or preservatives. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 19 years and older): Take 2 capsules, 1 time per day. Take with food, a few hours before or after taking other medications or natural health products. Recommended Duration of Use: Consult a health care practitioner for prolonged use.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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