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Health Canada NPN 02159589 Coenzyme Q10 (ubiquinone-10) 100 mg per capsule Vegan · Non-GMO · Gluten-free Made in Canada · GMP facility
CardioNOx CoQ10CardioNOx CoQ10 - benefits and key ingredients CardioNOx CoQ10 - lifestyleCardioNOx CoQ10 - ingredientsCardioNOx CoQ10 - supplement facts panel

AOR CardioNOx Coenzyme Q10 100mg - Heart & Energy Support | 30 Caps

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$32.66 CAD
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BrandAOR
Serving1 V-capsule (1-3 daily)
Licensed Natural Health ProductNPN 02159589
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORTS CELLULAR ENERGY PRODUCTION: Coenzyme Q10 is an essential factor in the production of cellular energy in the mitochondria - the energy-generating structures inside every cell - helping the body meet its natural energy demands.
  • SUPPORTS CARDIOVASCULAR HEALTH: Each vegan capsule provides 100 mg of Coenzyme Q10, helping to maintain and support healthy cardiovascular function - the heart is one of the body's most energy-demanding organs.
  • POWERFUL FAT-SOLUBLE ANTIOXIDANT: CoQ10 is a powerful fat-soluble antioxidant - a source of antioxidants that help protect cells against the effects of free radicals.
  • HIGH-POTENCY, TRANSPARENT LABEL: 100 mg of Coenzyme Q10 (ubiquinone-10) per capsule, printed plainly on the label - the only medicinal ingredient, no proprietary blend.
  • ALSO CONTAINS POTASSIUM NITRATE (NON-MEDICINAL): The formula's non-medicinal ingredients include potassium nitrate, providing 259 mg of nitrate, alongside green tea extract, citric acid and microcrystalline cellulose - dietary nitrate is a well-studied area of nutrition research on its own (see the research section below).
  • TAKE WITH A FAT-CONTAINING MEAL: Because CoQ10 is fat-soluble, the label directs 1 capsule 1 to 3 times daily with a fat-containing meal to support absorption.
  • VEGAN, NON-GMO, GLUTEN-FREE: A vegan V-capsule formula that is non-GMO and gluten-free, in a 30-capsule, up to 30-day supply bottle.
  • MADE IN CANADA, LICENSED NHP: Manufactured in a GMP-compliant Canadian facility by Advanced Orthomolecular Research (AOR). Licensed Natural Health Product, NPN 02159589.

Product description

CoQ10 for heart, energy and antioxidant support

AOR CardioNOx CoQ10

A closer look at AOR CardioNOx - 100 mg of Coenzyme Q10 (ubiquinone-10) per vegan capsule, supporting cardiovascular health, cellular energy production and antioxidant protection. Made in Canada. Licensed Natural Health Product NPN 02159589.

CardioNOx CoQ10 lifestyle
AOR CardioNOx CoQ10
Ubiquinone-10 · 100 mg per V-Capsule

CardioNOx CoQ10

Backed by the CoQ10 research base

Coenzyme Q10 is one of the most widely studied nutrients for cardiovascular and mitochondrial health, including the large Q-SYMBIO heart-failure trial.

The AOR difference

100 mg of Coenzyme Q10 per vegan capsule, made in Canada in a GMP-compliant facility and licensed by Health Canada, NPN 02159589.

What AOR CardioNOx Supports

Coenzyme Q10 is a natural component of every cell in the body - four ways it supports your heart and energy levels.

Mitochondrial Energy Production

CoQ10 is an essential factor in the production of cellular energy in the mitochondria, the energy-generating structures inside every cell.

Cardiovascular Health

Helps to maintain and support healthy cardiovascular function - the heart is one of the body's most energy-demanding organs.

Antioxidant Protection

A powerful fat-soluble antioxidant and a source of antioxidants that help protect cells against the effects of free radicals.

Fat-Soluble, Absorption-Minded Formula

Each vegan capsule is intended to be taken with a fat-containing meal - because CoQ10 is fat-soluble, this is how the label directs it to be used.

AOR CardioNOx CoQ10: Supplement Facts

AOR™CardioNOx CoQ10
English

Medicinal Ingredient (per capsule)

  • Coenzyme Q10 (ubiquinone-10)100 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: potassium nitrate (providing 259 mg nitrate), green tea extract, citric acid, microcrystalline cellulose. Capsule: hypromellose.

Recommended Use or Purpose: Contains Coenzyme Q10 (ubiquinone-10), an essential factor in the production of cellular energy in the mitochondria and a powerful fat-soluble antioxidant. Helps to maintain and support cardiovascular health. Source of an antioxidant. Licensed Natural Health Product, NPN 02159589.

Recommended Dose (Adults 18 years and older): Take 1 capsule one to three times daily with a fat-containing meal, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules - swallow capsules whole. Do not exceed the daily dose unless instructed by a health care practitioner.

Cautions and Warnings: Allergens: Corn. Consult a health care practitioner before use if you are taking blood pressure medication or blood thinners, if you are pregnant or breastfeeding, or if you have a liver disorder. Consult a health care practitioner before using this product for more than 12 weeks. Stop use and consult a health care practitioner if you develop symptoms of liver trouble such as yellowing of the skin or eyes (jaundice), stomach pain, dark urine, sweating, nausea and/or unusual tiredness or loss of appetite. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported in Canada and internationally. Keep out of reach of children. Store tightly sealed in a cool, dry place. Do not use if the safety seal is broken.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Ingrédient médicinal (par capsule)

  • Coenzyme Q10 (ubiquinone-10)100 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : nitrate de potassium (fournissant 259 mg de nitrate), extrait de thé vert, acide citrique, cellulose microcristalline. Capsule : hypromellose.

Usage ou fins recommandés : Contient de la coenzyme Q10 (ubiquinone-10), un facteur essentiel à la production d'énergie cellulaire dans les mitochondries et un puissant antioxydant liposoluble. Aide au maintien et au soutien de la santé cardiovasculaire. Source d'un antioxydant. Produit de santé naturel homologué, NPN 02159589.

Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule une à trois fois par jour avec un repas contenant des matières grasses, ou selon les directives d'un praticien de soins de santé qualifié. Ne pas écraser ni mélanger les capsules - avaler les capsules entières. Ne pas dépasser la dose quotidienne à moins d'avis contraire d'un praticien de soins de santé.

Mises en garde et précautions : Allergènes : Maïs. Consultez un praticien de soins de santé avant l'utilisation si vous prenez des médicaments pour la pression sanguine ou des anticoagulants, si vous êtes enceinte ou si vous allaitez, ou si vous avez un trouble hépatique. Consultez un praticien de soins de santé avant d'utiliser ce produit pendant plus de 12 semaines. Cessez l'utilisation et consultez un praticien de soins de santé si vous présentez des symptômes de troubles hépatiques tels que le jaunissement de la peau ou des yeux (jaunisse), des douleurs à l'estomac, des urines foncées, de la transpiration, des nausées et/ou une fatigue inhabituelle ou une perte d'appétit. De rares cas imprévisibles de lésions hépatiques associées aux produits contenant de l'extrait de thé vert ont été rapportés au Canada et à l'international. Garder hors de la portée des enfants. Conserver dans un endroit frais et sec, bien fermé. Ne pas utiliser si le sceau de sécurité est brisé.

NPN 02159589

100 mg Coenzyme Q10 per capsuleSupports cardiovascular healthVegan · Non-GMO · Gluten-freeMade in Canada

Support your heart and cellular energy the easy way

Get AOR CardioNOx on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR CardioNOx

One active ingredient, four ways it supports your heart and energy.

Mitochondrial Energy

Coenzyme Q10 is an essential factor in the production of cellular energy in the mitochondria - the energy-generating structures inside every cell.

Cardiovascular Health

Helps to maintain and support healthy cardiovascular function, backed by a large body of CoQ10 research including the Q-SYMBIO heart-failure trial.

Antioxidant Protection

A powerful fat-soluble antioxidant that helps protect cells against the effects of free radicals, as part of the body's natural defenses.

Transparent, High-Potency Label

100 mg of Coenzyme Q10 per vegan capsule - the full amount is printed on the label. Made in Canada, GMP-compliant, licensed NPN 02159589.

How AOR CardioNOx compares

Why a transparent, single-ingredient CoQ10 capsule matters.

 AOR CardioNOxLow-dose CoQ10Bargain blends
Coenzyme Q10 per capsule100 mgOften 30-50 mgVaries, often undisclosed
Capsule formatVegan V-capsuleOften gelatin-basedVaries
Per-capsule amount printedYes, 100 mgVariesProprietary blend possible
Single, disclosed activeCoenzyme Q10 onlyUsually singleMulti-ingredient blend
Sourcing and qualityMade in Canada - GMP - NPN Made in CanadaVariesVaries

How to use

Take 1 capsule

Adults take 1 V-capsule, 1 to 3 times daily, or as directed by a qualified health care practitioner.

With a fat-containing meal

Because CoQ10 is fat-soluble, take each capsule with a meal or snack that contains some fat to support absorption.

Swallow whole

Do not crush, mix or blend the capsules - swallow them whole with water.

Stay consistent

Use daily as directed; consult a health care practitioner before using this product for more than 12 weeks.

What the research says about Coenzyme Q10

Peer-reviewed studies and reviews on Coenzyme Q10 and related ingredient-level topics - shared for education, not as claims about this finished product. AOR CardioNOx's claims are the statements authorized under its Natural Health Product licence, NPN 02159589. The statin-depletion research is educational context only; this product is not positioned to treat statin side effects. The dietary-nitrate research concerns that topic at the ingredient level; potassium nitrate is a non-medicinal ingredient in this formula, not the basis of its medicinal claim.

CoQ10 - Heart Failure

Reduced major cardiovascular events (Q-SYMBIO)

In a 2-year randomized trial of 420 patients with moderate to severe heart failure, CoQ10 100 mg three times daily plus standard therapy reduced the composite of major adverse cardiovascular events (15% vs 26%) and cardiovascular mortality versus placebo.

Human RCT
Mortensen et al., JACC: Heart Failure (2014)
CoQ10 - Heart Failure

Cochrane review: lower mortality and hospitalization

A Cochrane review of 11 randomized trials (1,573 participants) found CoQ10 probably reduces all-cause mortality and hospitalization related to heart failure versus placebo or conventional therapy.

Cochrane meta-analysis
Al Saadi et al., Cochrane Database of Systematic Reviews (2021)
CoQ10 - Heart Failure

Improved ejection fraction and walk distance

A meta-analysis of 33 randomized trials found CoQ10 was associated with lower all-cause mortality and heart-failure hospitalization, alongside improved left ventricular ejection fraction and 6-minute walk test distance.

Meta-analysis
Xu et al., BMC Cardiovascular Disorders (2024)
Mitochondrial Energy Mechanism

CoQ10's central role in cellular redox balance

A comprehensive physiology review describes Coenzyme Q as central to the mitochondrial electron transport chain and to the cell's entire redox balance, in addition to several other cellular processes.

Review
Wang, Lilienfeldt & Hekimi, Physiological Reviews (2024)
Mitochondrial Energy Mechanism

The mobile electron carrier of the ETC

Ubiquinone (CoQ10) is described as a mobile component of the mitochondrial electron transport chain, ferrying electrons between complexes to support the production of cellular energy.

Review
Wang & Hekimi, Trends in Cell Biology (2016)
Mitochondrial Energy Mechanism

Facilitates ATP production via the electron transport chain

A state-of-the-art cardiology review explains that CoQ10 facilitates the production of adenosine triphosphate (ATP) in the mitochondria by participating in redox reactions within the electron transport chain.

Review
Sharma et al., Circulation: Heart Failure (2016)
Statins and CoQ10 - Educational

Statins lower plasma CoQ10

A review explains that statins (HMG-CoA reductase inhibitors) share a biosynthetic pathway with Coenzyme Q10, and that plasma CoQ10 levels are measurably lowered during statin treatment.

Review
Littarru & Langsjoen, Mitochondrion (2007)
Statins and CoQ10 - Educational

Meta-analysis on statin-associated muscle symptoms

A meta-analysis of 7 randomized trials (389 patients) found CoQ10 supplementation (100-600 mg/day) was associated with a significant reduction in muscle pain intensity in statin-treated patients, though results varied by study.

Meta-analysis
Kovacic, Habicht & Eckert, Journal of Nutritional Science (2025)
Statins and CoQ10 - Educational

Secondary CoQ10 deficiency, including from statins

A review of secondary CoQ10 deficiency disorders lists pharmacological agents such as statins among the recognized causes, alongside oxidative stress and other mechanisms unrelated to genetics.

Review
Mantle, Turton & Hargreaves, Frontiers in Bioscience (2022)
Dietary Nitrate and Nitric Oxide

The nitrate-nitrite-nitric oxide pathway

Dietary nitrate is converted in the body to nitrite and can be further converted to nitric oxide; supplementation has been shown to raise plasma nitrite and reduce resting blood pressure in some studies.

Review
Jones, Sports Medicine (2014)
Dietary Nitrate and Nitric Oxide

Modest blood-pressure effect in healthy people

A meta-analysis of 19 randomized trials found inorganic nitrate mildly reduced systolic blood pressure in healthy people, but did not significantly lower blood pressure in people with hypertension.

Meta-analysis
Zhang et al., Food & Function (2023)
Dietary Nitrate and Nitric Oxide

Mechanisms behind the blood-pressure effect

A physiology review describes how dietary inorganic nitrate, via the nitrate-nitrite-nitric oxide pathway, can influence vascular tone and has been studied for a blood-pressure-lowering effect.

Review
Carlstrom, Lundberg & Weitzberg, Acta Physiologica (2018)
Antioxidant Mechanism

CoQ recycling suppresses lipid peroxidation

A study identified a pathway (FSP1-CoQ-NAD(P)H) in which cells regenerate reduced CoQ to trap lipid peroxyl radicals, protecting against oxidative membrane damage.

Mechanistic study
Doll et al., Nature (2019)
Antioxidant Mechanism

Antioxidant and anti-inflammatory mechanisms reviewed

A narrative review describes CoQ10's antioxidant and anti-inflammatory properties, including its role in endothelial function and vascular smooth-muscle activity.

Review
Hosseini Roknabadi et al., Inflammopharmacology (2025)
Antioxidant Mechanism

Key antioxidant component of the electron transport chain

A review of CoQ10 in atherosclerosis describes it as a key component of electron transport chain Complex I and an important endogenous antioxidant that helps mitigate oxidative stress.

Review
Liao et al., European Journal of Pharmacology (2024)
Safety and Tolerability

Well tolerated at doses up to 1,800 mg/day

A dose-escalation study found CoQ10 supplementation was safe and well tolerated at doses as high as 1,800 mg per day, with short-term supplementation also lowering a marker of oxidative stress.

Human study
Yeung et al., BMC Nephrology (2015)
Safety and Tolerability

High-dose RCT: comparable adverse-event rates to placebo

A randomized, placebo-controlled trial of high-dose ubiquinol (1,500 mg/day) reported adverse-event rates comparable between the CoQ10 group (23.8%) and placebo (30.9%).

Human RCT
Mitsui et al., EClinicalMedicine (2023)
Safety and Tolerability

Probably safe with few drug interactions

A review concludes CoQ10 supplementation is probably safe and well tolerated, with few drug interactions and only minor side effects reported across the literature.

Review
Renke, Pereira & Renke, Current Diabetes Reviews (2023)
Bioavailability and Absorption

Absorption is slow due to hydrophobicity

A review explains that dietary CoQ10 absorption is slow and limited because of its hydrophobicity and large molecular weight, though solubilized supplement formulations show enhanced bioavailability.

Review
Bhagavan & Chopra, Free Radical Research (2006)
Bioavailability and Absorption

Crystal dispersion is critical to bioavailability

A review of CoQ10 absorption and metabolism notes that the degree of crystal dispersion in the initial formulation strongly affects bioavailability, with poor dispersion reducing absorption substantially.

Review
Mantle & Dybring, Antioxidants (2020)
Bioavailability and Absorption

Crystal-free formulation improves single-dose absorption

A randomized laboratory study found a crystal-free CoQ10 formulation achieved significantly greater single-dose absorption than crystalline or dry-powder CoQ10 formulations.

Human RCT
Judy, Integrative Medicine (2022)
Foundational CoQ10 Biochemistry

CoQ's biosynthesis and cellular roles

A biochemistry review traces how Coenzyme Q is synthesized in cells and describes its central role shuttling electrons in the electron transport chain, beyond its classic energy-production function.

Review
Guerra & Pagliarini, Trends in Biochemical Sciences (2023)
Foundational CoQ10 Biochemistry

Three decades of clinical cardiovascular research

A clinical-aspects update summarizes CoQ10's cardiovascular research history, including myocardial protection during cardiac surgery and studies of endothelial function.

Review
Littarru & Tiano, Current Opinion in Clinical Nutrition & Metabolic Care (2005)
Foundational CoQ10 Biochemistry

Deficiency patterns across ageing and disease

A review of CoQ10 supplementation summarizes how CoQ10 levels can decline with ageing or certain drugs, and how cardiovascular disease and inflammation appear to be alleviated by its antioxidant effect.

Review
Aaseth, Alexander & Alehagen, Mechanisms of Ageing and Development (2021)

Frequently asked questions

What is AOR CardioNOx?

It is a licensed Natural Health Product that provides 100 mg of Coenzyme Q10 (ubiquinone-10) per vegan capsule - an essential factor in cellular energy production and a powerful fat-soluble antioxidant that helps maintain and support cardiovascular health. NPN 02159589.

How do I take it?

Adults take 1 capsule, 1 to 3 times daily, with a fat-containing meal, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules - swallow them whole.

What are the non-medicinal ingredients?

Potassium nitrate (providing 259 mg nitrate), green tea extract, citric acid and microcrystalline cellulose, in a hypromellose (vegan) capsule.

Why does it contain potassium nitrate?

Potassium nitrate is listed as a non-medicinal ingredient on the label, providing 259 mg of nitrate. Dietary nitrate is a well-studied area of nutrition research on its own (see the research section below); it is not part of this product's medicinal claim, which is based on its Coenzyme Q10 content.

Why take it with a fat-containing meal?

Coenzyme Q10 is fat-soluble, so the label directs it to be taken with a meal that contains some fat to support absorption.

Is it vegan?

Yes. The capsule shell is hypromellose (vegan), and the formula is non-GMO and gluten-free.

Who should ask a health care practitioner before use?

Consult a health care practitioner before use if you are taking blood pressure medication or blood thinners, if you are pregnant or breastfeeding, if you have a liver disorder, or before using this product for more than 12 weeks. Stop use and consult a health care practitioner if you develop symptoms of liver trouble (yellowing of the skin or eyes, stomach pain, dark urine, sweating, nausea, unusual tiredness or loss of appetite) - rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported.

Where do I buy it?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.

100 mg Coenzyme Q10 per capsuleSupports cardiovascular healthVegan · Non-GMO · Gluten-freeMade in Canada

Support your heart and cellular energy the easy way

Get AOR CardioNOx on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 02159589. Contains Coenzyme Q10, an essential factor in the production of cellular energy in the mitochondria and a powerful fat-soluble antioxidant, helping to maintain and support cardiovascular health. The research summaries below concern Coenzyme Q10 and related ingredient-level topics and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use if you are taking blood pressure medication or blood thinners, if you are pregnant or breastfeeding, if you have a liver disorder, or before using this product for more than 12 weeks. Results may vary.

Important information

Safety Information

Cautions and Warnings: Allergens: Corn. Consult a health care practitioner before use if you are taking blood pressure medication or blood thinners, if you are pregnant or breastfeeding, or if you have a liver disorder. Consult a health care practitioner before using this product for more than 12 weeks. Stop use and consult a health care practitioner if you develop symptoms of liver trouble such as yellowing of the skin or eyes (jaundice), stomach pain, dark urine, sweating, nausea and/or unusual tiredness or loss of appetite. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported in Canada and internationally. Keep out of reach of children. Store tightly sealed in a cool, dry place. Do not use if the safety seal is broken.

Indications

Recommended Use or Purpose: Contains Coenzyme Q10 (ubiquinone-10), an essential factor in the production of cellular energy in the mitochondria and a powerful fat-soluble antioxidant. Helps to maintain and support cardiovascular health. Source of an antioxidant. Licensed Natural Health Product, NPN 02159589.

Ingredients

Medicinal Ingredient (per capsule): Coenzyme Q10 (ubiquinone-10) 100 mg. Non-medicinal ingredients: potassium nitrate (providing 259 mg nitrate), green tea extract, citric acid, microcrystalline cellulose. Capsule: hypromellose. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule one to three times daily with a fat-containing meal, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules - swallow capsules whole. Do not exceed the daily dose unless instructed by a health care practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.