CanPrev UTI Protect - Cranberry & D-Mannose | 60 Capsules
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 to 2 capsules, 2 times daily - adults 19+; 1 capsule, 2 times daily for ages 12-18 |
| Licensed Natural Health Product | NPN 80031854 |
| Quality Standards | GMP-compliant facility |
| Country | Formulated and made in Canada  |
About this item
- 250MG CRANBERRY + 150MG D-MANNOSE: Each vegetable capsule combines a full 250mg dose of cranberry fruit (Vaccinium macrocarpon) with 150mg of D-mannose, two of the most-studied ingredients for urinary tract wellness.
- HELPS PREVENT RECURRENT UTIs IN WOMEN: Helps prevent recurrent urinary tract infections in women. A source of antioxidants for the maintenance of good health.
- PARSLEY, GARLIC & GRAPESEED EXTRACTS: Also provides parsley (4:1 extract), allicin-standardized garlic (100:1 extract) and grapeseed extract standardized to 95% oligomeric pro-anthocyanidins in one complex formula.
- SIMPLE TWICE-DAILY DOSE: Adults take 1 to 2 capsules, 2 times daily - a 30-day supply in every 60-capsule bottle.
- REAL CAUTIONS - READ BEFORE USE: Do not use if pregnant. Consult a health care practitioner before use if breastfeeding, taking blood thinners or protease inhibitors, or if you have kidney stones, a kidney disorder, or diabetes.
- TRUSTED CANADIAN BRAND: Formulated and made in Canada by CanPrev, a Health Canada-licensed natural health product company. NPN 80031854.
Product Description
UTI Protect - D-Mannose, Cranberry, Parsley, Garlic & Grapeseed
A 5-ingredient vegetable capsule complex combining 250mg cranberry, 150mg D-mannose, parsley, garlic and grapeseed extracts. Helps prevent recurrent urinary tract infections in women and provides a source of antioxidants for the maintenance of good health. Licensed Natural Health Product - this product carries real cautions, see below. Licensed Natural Health Product NPN 80031854.
Un complexe en capsules végétales à 5 ingrédients combinant 250 mg de canneberge, 150 mg de D-mannose, ainsi que des extraits de persil, d'ail et de pépins de raisin. Aide à prévenir les infections urinaires récurrentes chez les femmes et constitue une source d'antioxydants pour le maintien d'une bonne santé. Produit de santé naturel homologué - ce produit comporte de réelles mises en garde, voir ci-dessous. NPN 80031854.
A 5-Ingredient Urinary Wellness Complex
Cranberry · D-Mannose · Parsley · Garlic · Grapeseed
250mg Cranberry + 150mg D-Mannose
Each vegetable capsule combines a full 250mg dose of cranberry fruit with 150mg of D-mannose - two of the most-studied ingredients for urinary tract wellness.
Parsley, Garlic & Grapeseed Extracts
Rounded out with a standardized parsley extract, allicin-standardized garlic and OPC-rich grapeseed extract for a broader botanical approach.
Advanced Ingredients, Superior Results
Cranberry and D-mannose are the two most-studied ingredients for urinary tract wellness, while parsley, garlic and grapeseed contribute traditional antioxidant and antimicrobial botanicals. Here is what the wider research explores on each.
Cranberry
Traditional fruit extract studied for compounds that may help discourage bacteria from adhering to the urinary tract lining.
250 mg (fruit, Vaccinium macrocarpon)D-Mannose
A naturally occurring simple sugar studied for its ability to bind uropathogenic bacteria so they can be flushed out in urine.
150 mgParsley
A traditional culinary herb used in herbal medicine for its mild diuretic and antioxidant properties.
65 mg (leaf, Petroselinum crispum, 4:1 extract equiv. to 260 mg dried leaf)
Garlic
Standardized for allicin, garlic's principal sulfur compound, studied for antibacterial activity.
20 mg (bulb, Allium sativum, 100:1 extract equiv. to 2000 mg dried bulb, std. to 1% allicin)Grapeseed
A concentrated source of OPC antioxidants studied for supporting the body's antioxidant defenses.
15 mg (seed, Vitis vinifera, extract std. to 95% oligomeric pro-anthocyanidins)CanPrev UTI Protect: Supplement Facts
Product Facts
- Cranberry (fruit, Vaccinium macrocarpon) per capsule250 mg
- D-Mannose150 mg
- Parsley (leaf, Petroselinum crispum) 4:1 extract, equiv. to 260 mg dried leaf65 mg
- Garlic (bulb, Allium sativum) 100:1 extract, equiv. to 2000 mg dried bulb, std. to 1% allicin20 mg
- Grapeseed (seed, Vitis vinifera) extract, std. to 95% oligomeric pro-anthocyanidins15 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Recommended Use or Purpose: Helps prevent recurrent urinary tract infections in women. A source of antioxidants for the maintenance of good health.
Recommended Dose: Adults (19 years and older) - Take 1 to 2 capsules, 2 times daily. Adolescents (12-18 years) - Take 1 capsule, 2 times daily, or as directed by a health care practitioner.
Cautions and Warnings: Do not use if you are pregnant. Consult a health care practitioner prior to use if you are breastfeeding, if you are taking blood thinners or protease inhibitors, or if you have kidney stones, a kidney disorder, or diabetes. Stop use and consult a health care practitioner if symptoms of an allergic reaction occur. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Info-produit
- Canneberge (fruit, Vaccinium macrocarpon) par capsule250 mg
- D-Mannose150 mg
- Persil (feuille, Petroselinum crispum) extrait 4:1, équiv. à 260 mg de feuille séchée65 mg
- Ail (bulbe, Allium sativum) extrait 100:1, équiv. à 2000 mg de bulbe séché, normalisé à 1 % d'allicine20 mg
- Pépins de raisin (graine, Vitis vinifera) extrait, normalisé à 95 % de proanthocyanidines oligomériques15 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose, stéarate de magnésium, cellulose microcristalline. Les ingrédients non médicinaux peuvent changer - lisez et suivez toujours l'étiquette pour des renseignements exacts sur les ingrédients, les mises en garde et les allergènes.
Usage ou fins recommandés : Aide à prévenir les infections urinaires récurrentes chez les femmes. Une source d'antioxydants pour le maintien d'une bonne santé.
Posologie recommandée : Adultes (19 ans et plus) - Prendre 1 à 2 capsules, 2 fois par jour. Adolescents (12 à 18 ans) - Prendre 1 capsule, 2 fois par jour, ou selon les directives d'un praticien de soins de santé.
Mises en garde : Ne pas utiliser si vous êtes enceinte. Consulter un praticien de soins de santé avant l'usage si vous allaitez, si vous prenez des anticoagulants ou des inhibiteurs de protéase, ou si vous avez des antécédents de calculs rénaux, une affection rénale, ou du diabète. Cesser l'utilisation et consulter un praticien de soins de santé si des symptômes d'une réaction allergique se manifestent. Garder hors de la portée des enfants.
NPN 80031854
Support urinary tract wellness with UTI Protect
Get CanPrev UTI Protect on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev UTI Protect
A 5-ingredient vegetable capsule complex built around 250mg cranberry and 150mg D-mannose - CanPrev quality, with real cautions you should read before use.
250mg Cranberry + 150mg D-Mannose
Each vegetable capsule pairs a full 250mg dose of cranberry fruit with 150mg of D-mannose, the two most-studied ingredients for urinary tract wellness.
Helps prevent recurrent UTIs in women
Helps prevent recurrent urinary tract infections in women. A source of antioxidants for the maintenance of good health.
5 real actives, twice-daily dosing
Take 1 to 2 capsules, 2 times daily - a 30-day supply in every 60-capsule bottle.
Real cautions, Canadian-made NHP
Formulated and made in Canada by CanPrev. Do not use if pregnant; consult a practitioner if breastfeeding, taking blood thinners/protease inhibitors, or with kidney stones, a kidney disorder, or diabetes. NPN 80031854.
Inside every capsule
250mg of cranberry (Vaccinium macrocarpon) with 150mg of D-mannose, plus parsley, allicin-standardized garlic and OPC-rich grapeseed extracts - a 5-ingredient vegetable capsule complex for urinary tract wellness in women.
How to use it
Adults: take 1 to 2 capsules, 2 times daily
Adults 19 years and older: take 1 to 2 capsules, 2 times daily, or as directed by a health care practitioner.
Adolescents (12-18): take 1 capsule, 2 times daily
Adolescents aged 12 to 18 years: take 1 capsule, 2 times daily.
A 30-day supply per bottle
Each bottle of 60 vegetable capsules provides up to a 30-day supply at the standard adult dose.
Read the cautions before you start
Do not use if pregnant. Consult a health care practitioner first if you are breastfeeding, taking blood thinners or protease inhibitors, or if you have kidney stones, a kidney disorder, or diabetes.
What the research says about this complex's ingredients
Educational summaries of published research on cranberry, D-mannose, parsley, garlic and grapeseed generally; not product-specific claims. CanPrev UTI Protect's own authorized use under NPN 80031854 is that it helps prevent recurrent urinary tract infections in women and is a source of antioxidants for the maintenance of good health.
A 2026 meta-analysis found D-mannose monotherapy did not significantly beat placebo across 5 studies
Pooling 3 placebo-controlled studies (831 women), D-mannose monotherapy showed a non-significant reduction in recurrent UTIs (risk ratio 0.37, 95% CI 0.11-1.30) with high heterogeneity; the authors concluded current evidence does not support its routine use alone, though it was well tolerated.
Meta-analysisA large network meta-analysis of 50 trials found D-mannose significantly reduced UTI incidence versus placebo
Comparing 14 non-antibiotic interventions across 50 randomized trials (10,495 subjects), D-mannose showed a significant reduction in UTI incidence versus placebo (risk ratio 0.34, 95% CI 0.21-0.56), among the strongest effects of any intervention studied, alongside cranberry and probiotics.
Network meta-analysisA pilot study combining D-mannose with cranberry proanthocyanidins found over 3 in 4 women stayed infection-free
In 26 women with recurrent postcoital UTIs given a combined D-mannose (2000mg) plus proanthocyanidin (140mg) formulation for 6 months, UTI incidence fell significantly and 76.2% of participants remained infection-free at the final visit, with high treatment adherence and only one withdrawal.
Human pilot study (n=26)A crossover study found cranberry blocked more types of bacterial adhesion than D-mannose alone
Comparing urine collected after cranberry extract (36mg soluble proanthocyanidins) versus D-mannose intake, cranberry showed anti-adhesion activity against both P-type and Type 1-fimbriated uropathogenic E. coli, while D-mannose only prevented Type 1 adhesion - and cranberry's urinary activity was more robust and consistent over the study period.
Human crossover studyUrine from volunteers taking a cranberry + D-mannose + vitamin C combination reduced bacterial adhesion to bladder cells
After healthy volunteers consumed a nutraceutical combining A-type proanthocyanidin-rich cranberry extract, D-mannose and ascorbic acid, their urine significantly reduced adhesion of uropathogenic E. coli to bladder epithelial cells in vitro, an effect the authors linked to both anti-adhesive and anti-inflammatory mechanisms.
Human ex vivo studyA review describes cranberry proanthocyanidins disrupting bacterial cell-to-cell communication
Reviewing proanthocyanidins' effects on major urinary pathogens including E. coli, Pseudomonas aeruginosa and Proteus mirabilis, the compounds were found to interfere with quorum sensing - the signaling bacteria use to coordinate biofilm formation - in addition to their established anti-adhesion activity.
ReviewA meta-analysis of 23 trials found cranberry reduced UTI risk by 30% in susceptible populations
Pooling 3,979 participants across 23 trials, cranberry-based products significantly reduced UTI incidence overall (risk ratio 0.70), with a 32% relative risk reduction specifically in women with recurrent UTIs - one of the larger, more rigorous cranberry meta-analyses using trial sequential analysis to confirm the finding.
Meta-analysisA meta-analysis of 7 trials in healthy women found cranberry reduced UTI recurrence by 26%
Reviewing 7 randomized trials in 1,498 generally healthy women with a history of UTI, cranberry intake reduced the risk of UTI recurrence by 26% versus placebo or control (pooled risk ratio 0.74), though the authors noted most studies were relatively small and called for larger confirmatory trials.
Meta-analysisA methodological review explains why different cranberry meta-analyses have reached conflicting conclusions
Comparing major cranberry meta-analyses, this review found that studies weighting evidence toward women with recurrent UTIs specifically found stronger benefit (risk ratio as low as 0.53) than analyses including broader, less-susceptible populations - a reminder that population selection materially changes the apparent effect size.
Methodological reviewAllicin showed direct antibacterial activity against drug-resistant E. coli in a 2026 study
Testing allicin, garlic's principal bioactive sulfur compound, against carbapenem-resistant E. coli producing New Delhi metallo-beta-lactamase, allicin showed potent antibacterial activity (MIC 8-64 µg/mL) both in vitro and in animal infection models, working by inducing oxidative stress in bacterial cells.
Preclinical studyAllicin was found to inhibit an enzyme bacteria need to replicate their DNA
Using isotopic labeling to track oxidized proteins, researchers identified bacterial DNA gyrase as a direct target of allicin, with allicin inhibiting E. coli DNA gyrase activity in vitro in a similar concentration range to the antibiotic nalidixic acid - a specific molecular mechanism behind garlic's antibacterial reputation.
Preclinical studyCombining allicin with antibiotics produced faster bacterial kill rates than either alone
Testing allicin alongside six different antibiotics against E. coli and B. subtilis, every synergistic allicin-antibiotic combination killed bacteria significantly faster than the antibiotic alone, with the allicin-rifaximin pairing showing the strongest effect - suggesting allicin may complement, not just substitute for, conventional antimicrobials.
Preclinical studyA review documents parsley's long traditional use as a urinary-tract antiseptic and diuretic
Surveying ethnomedicinal and pharmacological literature on Petroselinum crispum, parsley has traditional use as a diuretic and antiseptic of the urinary tract, with modern research also describing antioxidant, antibacterial and antifungal activity attributed to its flavonoid content, particularly apigenin.
ReviewParsley's phenolic and flavonoid constituents are linked to antimicrobial and antioxidative properties
A review of parsley's chemical constituents - including coumarins, ascorbic acid, carotenoids and flavonoids - describes a range of possible medicinal properties including antimicrobial, antioxidative, diuretic and anti-hypertensive effects, while noting more extensive clinical research is still needed.
ReviewApigenin, parsley's main flavonoid, shows anti-inflammatory and antioxidant activity in pharmaceutical research
A pharmaceutical formulation study of parsley extract identifies apigenin and its glycosides as the leaf's principal flavonoids, describing apigenin's anti-inflammatory and antioxidant activity as the basis for developing standardized parsley-derived preparations.
Pharmaceutical studyA meta-analysis of 19 trials found grapeseed extract significantly lowered markers of oxidative stress
Pooling 19 controlled trials, grapeseed extract supplementation significantly reduced malondialdehyde (a lipid-oxidation marker), oxidized LDL and C-reactive protein, with a marginal increase in total antioxidant capacity - evidence the authors describe as modulating the body's redox system, chiefly by inhibiting lipid peroxidation.
Meta-analysisA randomized trial found grapeseed extract reduced oxidative stress markers over 2 months
In 50 patients with non-alcoholic fatty liver disease given 250mg of grapeseed proanthocyanidins daily for 2 months, the supplement group showed greater reductions in inflammatory (IL-6) and oxidative-stress (MDA) markers and greater increases in antioxidant enzymes (SOD, GPx) than placebo.
Human RCT (n=50)A 70-year research history links standardized grapeseed extract to favorable vascular and antioxidant effects in healthy adults
Tracing grapeseed proanthocyanidin extract research back to its 1947 origins, this review describes 8-week human supplementation studies showing favorable changes in vascular function and gene expression of inflammatory pathways in healthy volunteers' white blood cells.
Review50-60% of adult women will have a UTI in their lifetime, and up to 1 in 4 of those recurs
A 2025 meta-analysis notes that approximately 50-60% of adult women experience at least one urinary tract infection during their lifetime, with 20-24% of those women experiencing a recurrence within a year - the scale of the problem non-antibiotic prevention strategies aim to address.
Meta-analysisAn overview of 27 systematic reviews found cranberry among the better-supported non-antibiotic options
Reviewing 27 systematic reviews of non-antibiotic interventions for recurrent UTI in women, cranberry and methenamine hippurate were supported by the evidence base, while reviews of D-mannose, probiotics, herbal medicine and other options concluded that stronger evidence is still needed, with questions remaining around optimal dose and duration for all.
Overview of systematic reviewsAn earlier meta-analysis of 17 trials found cranberry reduced recurrence by nearly half
Reviewing 17 randomized trials of non-antibiotic prophylaxis for recurrent UTI, cranberry products decreased recurrence (risk ratio 0.53, 95% CI 0.33-0.83) in a pooled analysis of 250 participants, a similar magnitude of effect to acupuncture and smaller than the oral immunostimulant OM-89 in the same review.
Meta-analysisA case report links a week of cranberry sauce intake to a near-doubled INR in a patient on warfarin
A 75-year-old man stable on warfarin for 10 months saw his INR rise from a therapeutic 2-3 range to 4.8 after consuming roughly 113g of cranberry sauce daily for 7 days; his INR returned to 2.2 within a week of stopping, with no other diet or medication changes identified.
Case reportA systematic review of herb-drug interactions found garlic can lower blood levels of warfarin
Reviewing documented interactions between top-selling herbal medicines and prescribed drugs, garlic was found to decrease blood concentrations of warfarin and to produce hypoglycemia when combined with the diabetes drug chlorpropamide - part of a wider evidence base on herb-drug interactions clinicians should ask patients about.
Systematic reviewA review of older adults found garlic among the herbal products most often flagged for bleeding risk with anticoagulants
A systematic review of concurrent herbal and prescription drug use in older adults found garlic, alongside ginkgo biloba and ginseng, was the herbal product most frequently reported to carry a potential bleeding risk when combined with aspirin or warfarin - the basis for this product's blood-thinner caution.
Systematic reviewFrequently asked questions
What is CanPrev UTI Protect and what does it do?
It's a vegetable capsule complex combining 250mg of cranberry with 150mg of D-mannose, plus parsley, garlic and grapeseed extracts. It helps prevent recurrent urinary tract infections in women and provides a source of antioxidants for the maintenance of good health.
How do I take it?
Adults (19 years and older) take 1 to 2 capsules, 2 times daily. Adolescents (12-18 years) take 1 capsule, 2 times daily, or as directed by a qualified health care practitioner.
Is this product only for women?
Its authorized use is specifically to help prevent recurrent urinary tract infections in women, per its Health Canada license. Adolescents ages 12-18 have a separate labeled dose.
Who should NOT use this product?
Do not use if you are pregnant.
Who should ask a health care practitioner before using it?
Consult a health care practitioner before use if you are breastfeeding, if you are taking blood thinners or protease inhibitors, or if you have kidney stones, a kidney disorder, or diabetes.
What should I do if I have an allergic reaction?
Stop use and consult a health care practitioner if symptoms of an allergic reaction occur.
How long does one bottle last?
Each bottle contains 60 vegetable capsules - up to a 30-day supply at the standard adult dose of 1 to 2 capsules, 2 times daily.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support urinary tract wellness with UTI Protect
Get CanPrev UTI Protect on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80031854. Helps prevent recurrent urinary tract infections in women. A source of antioxidants for the maintenance of good health. This product has real cautions: do not use if you are pregnant; consult a health care practitioner before use if you are breastfeeding, taking blood thinners or protease inhibitors, or if you have kidney stones, a kidney disorder, or diabetes. The research summaries below concern the ingredients generally and are educational - they are not claims about this finished product. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Do not use if you are pregnant. Consult a health care practitioner prior to use if you are breastfeeding, if you are taking blood thinners or protease inhibitors, or if you have kidney stones, a kidney disorder, or diabetes. Stop use and consult a health care practitioner if symptoms of an allergic reaction occur. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps prevent recurrent urinary tract infections in women. A source of antioxidants for the maintenance of good health.
Ingredients
Medicinal ingredients (per vegetable capsule): Cranberry (fruit, Vaccinium macrocarpon) 250 mg, D-Mannose 150 mg, Parsley (leaf, Petroselinum crispum) 4:1 extract equivalent to 260 mg dried leaf 65 mg, Garlic (bulb, Allium sativum) 100:1 extract equivalent to 2000 mg dried bulb, standardized to 1% allicin, 20 mg, Grapeseed (seed, Vitis vinifera) extract, standardized to 95% oligomeric pro-anthocyanidins, 15 mg. Non-medicinal ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose: Adults (19 years and older) - Take 1 to 2 capsules, 2 times daily. Adolescents (12-18 years) - Take 1 capsule, 2 times daily, or as directed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.