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Health Canada NPN 80062037 100mg Kaneka Ubiquinol (Active CoQ10) per Softgel Non-GMO · Gluten-Free · Dairy-Free 60 Softgels · 2-Month Supply · Made in Canada
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CanPrev Ubiquinol 100mg with MCT Oil - Active CoQ10 | 60 Softgels

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BrandCanPrev
Serving1 softgel daily - 100mg Ubiquinol (Kaneka Ubiquinol)
Licensed Natural Health ProductNPN 80062037
Quality StandardsGMP-compliant facility
Made InMade in Canada Made in Canada

About this item

  • ACTIVE FORM COQ10 - NO CONVERSION NEEDED: 100mg of Ubiquinol (Kaneka Ubiquinol), the already-reduced, active form of Coenzyme Q10, ready for the body to use directly.
  • ENHANCED ABSORPTION WITH MCT OIL: Formulated in a base of medium chain triglycerides (MCT oil, from coconut) to support absorption of this fat-soluble nutrient.
  • SUPPORTS CARDIOVASCULAR HEALTH: Helps to support cardiovascular health - CoQ10 is a key cofactor in mitochondrial energy production, especially important for the heart.
  • HELPS REDUCE MIGRAINE FREQUENCY: Helps to reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a preventative - use for at least 3 months to see beneficial effects.
  • EASY-TO-SWALLOW SOFTGEL: A convenient once-daily softgel instead of a large capsule or powder - simple to fit into a daily routine.
  • CLEAN FORMULA: Non-GMO, gluten-free, dairy-free and soy-free, made without artificial colours, flavours or preservatives.
  • 60 SOFTGELS - A FULL 2-MONTH SUPPLY: At the standard one-softgel-per-day dose, one bottle provides a full 60 days of supply.
  • MADE IN CANADA BY CANPREV: Formulated and made in Canada by CanPrev, a Health Canada-licensed natural health product company. NPN 80062037.

Customer Reviews

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Product Description

Ubiquinol 100 with MCT Oil - Active-Form CoQ10 for Heart Health and Migraine Prevention

CanPrev Ubiquinol 100mg

100mg of Kaneka Ubiquinol per softgel - the active, already-reduced form of Coenzyme Q10 - formulated in a base of MCT oil (from coconut) for enhanced absorption. Helps to support cardiovascular health, and helps to reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a preventative. Licensed Natural Health Product NPN 80062037.

100 mg d'Ubiquinol Kaneka par gélule - la forme active et déjà réduite de la coenzyme Q10 - formulée dans une base d'huile MCT (de noix de coco) pour une absorption améliorée. Aide à soutenir la santé cardiovasculaire, et aide à réduire la fréquence des migraines ainsi que les nausées et vomissements associés lorsqu'utilisé de façon préventive. Produit de santé naturel homologué. NPN 80062037.

Ubiquinol 100mg lifestyle
CanPrev Ubiquinol 100mg
100mg Kaneka Ubiquinol (Active CoQ10) · MCT Oil

Active Form, Enhanced Absorption

100mg Kaneka Ubiquinol per Softgel - MCT Oil Base, Non-GMO, Gluten-Free, Dairy-Free

Active-Form CoQ10 - No Conversion Needed

Ubiquinol is the body's own active, reduced form of CoQ10 - unlike ubiquinone, it doesn't require conversion before the body can use it, which may matter more as natural CoQ10 conversion tends to decline with age.

A Real, Licensed Migraine-Prevention Claim

Licensed under NPN 80062037 to help reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a prophylactic for at least 3 months - not every CoQ10 product carries this claim.

What CanPrev Ubiquinol 100 Supports

Coenzyme Q10 is one of the most researched nutrients for heart and cellular energy - and its active, reduced ubiquinol form has its own body of clinical research. Here is what the wider research on ubiquinol and CoQ10 explores.

Cardiovascular Health

Helps to support cardiovascular health - the heart is one of the body's most energy-demanding organs, and CoQ10 is a key mitochondrial cofactor.

Migraine Prevention

Helps to reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a prophylactic for at least 3 months.

Antioxidant Support

Ubiquinol is CoQ10's active antioxidant form, helping protect cells against the effects of free radicals.

Enhanced Absorption with MCT Oil

Formulated in a base of medium chain triglycerides (from coconut) to support absorption of this fat-soluble nutrient - in an easy-to-swallow softgel.

CanPrev Ubiquinol 100mg: Supplement Facts

CanPrev™Ubiquinol 100mg
English

Supplement Facts

  • Ubiquinol per 1 softgel100 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Medium chain triglycerides (from coconut), purified water, glycerin, gelatin, silica, iron oxide (brown).

Recommended Use or Purpose: Helps to support cardiovascular health. Helps to reduce the frequency of migraine headaches and associated symptoms such as nausea and vomiting when taken as a prophylactic.

Recommended Dose (Adults 19 years and older): Take one (1) softgel per day with food, or as directed by a health care practitioner. For migraine prevention, take one (1) softgel two (2) times per day. Duration of Use: As a migraine preventative, use for a minimum of 3 months to see the beneficial effects.

Cautions and Warnings: As with any natural health product, consult a health care practitioner on the use of this product, especially if you are taking blood thinners or blood pressure medication, or if you have a medical condition. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. If the frequency of migraines increases, and associated symptoms such as nausea and vomiting persist or worsen, consult a health care practitioner. Do not use if the safety seal is broken. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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Fiche produit

  • Ubiquinol par 1 gélule100 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Triglycérides à chaîne moyenne (de noix de coco), eau purifiée, glycérine, gélatine, silice, oxyde de fer (brun).

Usage ou fins recommandés : Aide à soutenir la santé cardiovasculaire. Aide à réduire la fréquence des migraines ainsi que les symptômes associés tels que nausées et vomissements lorsqu'il est pris à titre préventif.

Posologie recommandée (adultes de 19 ans et plus) : Prendre une (1) gélule par jour avec de la nourriture, ou selon les directives d'un praticien de soins de santé. Pour la prévention des migraines, prendre une (1) gélule deux (2) fois par jour. Durée d'utilisation : En prévention des migraines, utiliser pendant un minimum de 3 mois pour observer les effets bénéfiques.

Mises en garde et avertissements : Comme pour tout produit de santé naturel, consultez un praticien de soins de santé concernant l'utilisation de ce produit, surtout si vous prenez des anticoagulants ou des médicaments pour la pression artérielle, ou si vous souffrez d'un état médical. Consultez un praticien de soins de santé avant l'usage si vous êtes enceinte ou si vous allaitez. Si la fréquence des migraines augmente, et que des symptômes associés tels que nausées et vomissements persistent ou s'aggravent, consultez un praticien de soins de santé. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants.

NPN 80062037

100mg Kaneka Ubiquinol (Active CoQ10)MCT Oil for Enhanced Absorption60 Softgels · 2-Month SupplyNon-GMO · Gluten-Free · Dairy-Free

Support your heart and energy with active-form CoQ10

Get CanPrev Ubiquinol 100 with MCT Oil on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev Ubiquinol 100 with MCT Oil

100mg of active-form CoQ10 per softgel, absorbed with MCT oil - premium CanPrev quality, Made in Canada.

The active, reduced form - no conversion required

Ubiquinol is the form the body actually uses at the cellular level - unlike ubiquinone, it doesn't need to be converted first, which may matter more as natural conversion ability declines with age.

MCT oil for enhanced absorption

CoQ10 is fat-soluble and can be poorly absorbed on its own; this softgel is formulated in a base of medium chain triglycerides (from coconut) to support uptake.

Two real, licensed claims - not just marketing

NPN 80062037 authorizes this product to help support cardiovascular health and to help reduce the frequency of migraine headaches and associated nausea and vomiting when used preventatively.

Clean, Canadian-made formula

Non-GMO, gluten-free, dairy-free and soy-free, formulated and made in Canada by CanPrev, a Health Canada-licensed natural health product company. NPN 80062037.

How to use it

Take 1 softgel daily with food

Adults (19 years and older): take one (1) softgel per day with food, or as directed by a health care practitioner.

For migraine prevention, take 1 softgel twice daily

For migraine prevention, take one (1) softgel two (2) times per day.

Stay consistent for at least 3 months

As a migraine preventative, use for a minimum of 3 months to see the beneficial effects.

Store safely and check with a practitioner

Keep out of reach of children; do not use if the safety seal is broken. Consult a health care practitioner before use if pregnant, breastfeeding, taking blood pressure medication or blood thinners, or if you have a medical condition.

What the research says about Ubiquinol and Coenzyme Q10

Educational summaries of published research on Coenzyme Q10 and its active ubiquinol form generally; not product-specific claims. CanPrev Ubiquinol 100's own authorized use under NPN 80062037 is that it helps to support cardiovascular health and helps to reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a prophylactic.

Ubiquinol vs Ubiquinone - Why the Active Form

Kaneka's own ubiquinol shown safe and well absorbed in humans

In double-blind, placebo-controlled studies, single and 4-week multiple oral doses of Kaneka ubiquinol (the same branded ubiquinol source used in this product) produced significant, dose-related increases in plasma ubiquinol with no clinically relevant safety findings, confirming real gastrointestinal absorption of the reduced form.

Human study
Hosoe et al., Regulatory Toxicology and Pharmacology (2006)
Ubiquinol vs Ubiquinone - Why the Active Form

Ubiquinol raised plasma CoQ and improved mitochondrial coupling efficiency

In a randomized, double-blind trial, 300mg/day of ubiquinol for six weeks increased plasma coenzyme Q concentration and a marker of mitochondrial oxidative phosphorylation coupling efficiency in healthy, active men - the reduced form is noted to have greater bioavailability than the oxidized ubiquinone form typically studied previously.

Human RCT
Acton et al., European Journal of Applied Physiology (2026)
Ubiquinol vs Ubiquinone - Why the Active Form

About 95% of the body's own CoQ10 normally circulates as ubiquinol

A review of CoQ10 formulations notes that roughly 95% of circulating coenzyme Q10 in humans naturally occurs in the reduced ubiquinol form, and that solubilized CoQ10 formulations show superior plasma bioavailability over standard powder forms.

Review
Bhagavan & Chopra, Mitochondrion (2007)
Coenzyme Q10 and Heart Failure (Q-SYMBIO)

Q-SYMBIO: CoQ10 reduced major cardiovascular events in heart failure

In a 2-year, 420-patient randomized double-blind trial, CoQ10 100mg three times daily (added to standard heart-failure therapy) reduced the composite of major adverse cardiovascular events (15% vs 26%) plus cardiovascular and all-cause mortality compared with placebo.

Human RCT
Mortensen et al., JACC: Heart Failure (2014)
Coenzyme Q10 and Heart Failure (Q-SYMBIO)

Benefit confirmed in the trial's European sub-population

A sub-group analysis of Q-SYMBIO's European patients confirmed CoQ10's effect in safely reducing major adverse cardiovascular events, all-cause and cardiovascular mortality and hospitalization, and found a significant improvement in left ventricular ejection fraction.

Human RCT sub-analysis
Mortensen et al., Cardiology Journal (2019)
Coenzyme Q10 and Heart Failure (Q-SYMBIO)

A state-of-the-art review notes a relatively clean safety profile

Reviewing three decades of heart-failure research, this review highlights Q-SYMBIO's reduction in major adverse cardiovascular events and notes CoQ10 is relatively safe with few drug interactions, while calling for larger confirmatory trials.

Review
Sharma et al., Circulation: Heart Failure (2016)
Coenzyme Q10 and Migraine Prevention

A placebo-controlled trial found CoQ10 superior for migraine frequency and nausea

In a double-blind, randomized trial of 42 migraine patients, CoQ10 (3 x 100mg/day) outperformed placebo for attack frequency, headache-days and days with nausea by the third treatment month, with a 50%-responder rate of 47.6% versus 14.4% for placebo.

Human RCT
Sandor et al., Neurology (2005)
Coenzyme Q10 and Migraine Prevention

A meta-analysis found CoQ10 reduced attack duration and frequency

Pooling 6 randomized trials (371 participants), CoQ10 supplementation reduced both the duration and frequency of migraine attacks compared with control, though it did not significantly reduce headache severity in the pooled analysis.

Meta-analysis
Sazali et al., BMJ Open (2021)
Coenzyme Q10 and Migraine Prevention

A pediatric RCT found CoQ10 comparable to a prescription option, with fewer side effects

In a randomized trial of 72 children and adolescents with migraine, CoQ10 showed therapeutic effects comparable to amitriptyline by 3 months, with fewer reported side effects, particularly with longer-term use.

Human RCT
Yaghini et al., Advanced Biomedical Research (2022)
Ubiquinol - Clinical Evidence Across Populations

Ubiquinol improved blood-vessel function in people with mild dyslipidemia

In a randomized trial of 48 adults with elevated LDL cholesterol and mild endothelial dysfunction, 8 weeks of ubiquinol (100 or 200mg/day) significantly improved flow-mediated dilation of the brachial artery versus placebo, linked to increased nitric oxide availability.

Human RCT
Sabbatinelli et al., Nutrients (2020)
Ubiquinol - Clinical Evidence Across Populations

Ubiquinol curbed post-surgical CoQ10 decline in elderly heart-valve patients

In 50 elderly patients undergoing aortic valve replacement, ubiquinol (400mg/day, from 7 days before to 5 days after surgery) counteracted the post-operative drop in plasma CoQ10 and oxidative stress, and blunted the rise in cardiac troponin I compared with placebo.

Human RCT
Orlando et al., Aging (2020)
Ubiquinol - Clinical Evidence Across Populations

Reduced-form CoQ10 increased intracellular levels even under major physiological stress

In burn-injury patients, high-dose reduced CoQ10 (ubiquinol-10) supplementation increased both plasma concentrations and intracellular CoQ10 content in immune cells compared with placebo, demonstrating real bioavailability of the reduced form.

Human RCT
Kuriyama et al., Metabolites (2022)
Mitochondrial Energy Mechanism

A key cellular pathway regenerates reduced CoQ to guard against oxidative damage

Researchers identified the FSP1-CoQ-NAD(P)H pathway, in which cells regenerate the reduced (ubiquinol) form of coenzyme Q to trap damaging lipid peroxyl radicals - part of the same redox system that shuttles electrons for mitochondrial energy production.

Mechanistic study
Doll et al., Nature (2019)
Mitochondrial Energy Mechanism

Vitamin E and CoQ form an interconnected antioxidant recycling network

A review of 'free radical reductase' enzymes describes how cells continuously regenerate reduced coenzyme Q in mitochondrial, ER and plasma membranes, working together with vitamin E to protect lipid membranes from oxidative damage.

Review
Kagan et al., Antioxidants & Redox Signaling (2023)
Mitochondrial Energy Mechanism

Foundational review: CoQ10 is the respiratory chain's electron carrier

A mitochondrial medicine review describes coenzyme Q10 as the electron carrier of the respiratory chain that generates ATP, and notes that oral CoQ10 supplementation has been used to help restore plasma levels lowered by statin medications.

Review
Fosslien, Annals of Clinical and Laboratory Science (2001)
Antioxidant Mechanism and Free Radical Defense

CoQ10 is both a bioenergetic cofactor and an important antioxidant

A pharmacokinetics review describes coenzyme Q10's dual role in cellular energy production and as a lipid-soluble antioxidant, noting that its slow, limited natural absorption can be improved with better-formulated supplements.

Review
Bhagavan & Chopra, Free Radical Research (2006)
Antioxidant Mechanism and Free Radical Defense

CoQ10 supplementation roughly doubled LDL-ubiquinol content in an aging study

In 70 healthy volunteers aged 28-77, LDL antioxidant capacity declined with age in men; giving a subset of participants 100mg/day of CoQ10 significantly increased LDL-ubiquinol concentration, roughly doubling ubiquinol-carrying LDL particles.

Human study
Aejmelaeus et al., Molecular Aspects of Medicine (1997)
Antioxidant Mechanism and Free Radical Defense

Higher-dose CoQ10 reduced a marker of oxidative damage in Parkinson's patients

An open-label dose-escalation study in early Parkinson's disease found CoQ10 (400-1200mg/day) significantly lowered a marker of oxidative lipid damage (F2-isoprostanes), with the therapeutic response linked to participants' baseline ubiquinol levels.

Human trial
Seet et al., Antioxidants & Redox Signaling (2014)
Statins and CoQ10 - Educational

Statins deplete isoprenoid compounds needed for healthy muscle, not just cholesterol

A review of statin-associated muscle toxicity explains that statins block an enzyme upstream in the same pathway that produces CoQ10 and other isoprenoids, implicating this broader depletion - not just lower muscle cholesterol - in statin-related muscle symptoms.

Review
Baker, Muscle & Nerve (2005)
Statins and CoQ10 - Educational

The same pathway statins block also makes the body's CoQ10

A review of dyslipidemia and cardiovascular risk explains that statins, by targeting the mevalonate pathway to lower cholesterol, coincidentally reduce synthesis of coenzyme Q10 - a key mitochondrial cofactor and antioxidant - and discusses CoQ10 supplementation as a way to help offset this.

Review
Mthembu et al., Biochimie (2022)
Statins and CoQ10 - Educational

A liquid CoQ10 supplement eased statin-related muscle symptoms in a placebo-controlled trial

In 60 statin-intolerant patients restarted on half-dose statin therapy, adding a liquid CoQ10 supplement (100mg/day for 3 months) significantly improved clinical myalgia and pain scores compared with placebo.

Human RCT
Derosa et al., Drug Design, Development and Therapy (2019)
Safety and Tolerability

Kaneka Q10 well tolerated up to 900mg/day in healthy adults

A double-blind, randomized, placebo-controlled trial in 88 healthy adults found Kaneka-brand CoQ10 (the same source used in Kaneka ubiquinol) well tolerated at doses up to 900mg/day for 4 weeks, with no dose-related adverse events and no clinically significant changes in blood chemistry.

Human RCT
Ikematsu et al., Regulatory Toxicology and Pharmacology (2006)
Safety and Tolerability

Even very high doses were generally well tolerated in an open-label study

An open-label dose-escalation study found CoQ10 doses up to 3,000mg/day (with vitamin E) were generally well tolerated in Parkinson's disease patients, with adverse events typically judged unrelated to CoQ10 and plasma levels plateauing at 2,400mg/day.

Human trial
Shults et al., Experimental Neurology (2004)
Safety and Tolerability

A systematic review of coronary heart disease trials found CoQ10 appears safe

Reviewing recent randomized trials of CoQ10 in coronary heart disease and heart failure, this systematic review concludes CoQ10 appears to be safe, while noting current evidence does not support its routine use for blood pressure, cholesterol or glycemic control specifically.

Systematic review
Ayers et al., Current Atherosclerosis Reports (2018)

Customer Reviews

4.7 out of 5 · 208 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

What is CanPrev Ubiquinol 100 with MCT Oil and what does it do?

It's a 100mg softgel dose of Ubiquinol - the active, reduced form of Coenzyme Q10 - formulated with MCT oil. It helps to support cardiovascular health and helps to reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a preventative.

Is this ubiquinol or ubiquinone?

This product uses Ubiquinol - specifically Kaneka Ubiquinol, the active, already-reduced form of CoQ10 - not the more common oxidized ubiquinone form.

How do I take it?

Adults (19 years and older) take one (1) softgel per day with food, or as directed by a health care practitioner. For migraine prevention, take one (1) softgel two (2) times per day, for at least 3 months to see beneficial effects.

Why MCT oil?

Ubiquinol is fat-soluble. This softgel is formulated in a base of medium chain triglycerides (from coconut) to help support its absorption.

How long does one bottle last?

Each bottle contains 60 softgels - at the standard dose of one softgel daily, that's a 2-month supply.

Is it vegan?

No - the softgel shell is made with gelatin. It is non-GMO, gluten-free, dairy-free and soy-free.

Who should use caution, or not use it?

Consult a health care practitioner before use if you are pregnant, breastfeeding, taking blood pressure medication or blood thinners, or if you have a medical condition. If migraine frequency increases, or associated nausea and vomiting persist or worsen, consult a health care practitioner. Keep out of reach of children and do not use if the safety seal is broken.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

100mg Kaneka Ubiquinol (Active CoQ10)MCT Oil for Enhanced Absorption60 Softgels · 2-Month SupplyNon-GMO · Gluten-Free · Dairy-Free

Support your heart and energy with active-form CoQ10

Get CanPrev Ubiquinol 100 with MCT Oil on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80062037. Helps to support cardiovascular health. Helps to reduce the frequency of migraine headaches and associated symptoms such as nausea and vomiting when taken as a prophylactic (use for a minimum of 3 months to see beneficial effects). The research summaries below concern Coenzyme Q10 and ubiquinol generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use, especially if you are pregnant, breastfeeding, taking blood pressure medication or blood thinners, or if you have a medical condition. Results may vary.

Important information

Safety Information

Cautions and Warnings: As with any natural health product, consult a health care practitioner on the use of this product, especially if you are taking blood thinners or blood pressure medication, or if you have a medical condition. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. If the frequency of migraines increases, and associated symptoms such as nausea and vomiting persist or worsen, consult a health care practitioner. Do not use if the safety seal is broken. Keep out of reach of children.

Indications

Recommended Use or Purpose: Helps to support cardiovascular health. Helps to reduce the frequency of migraine headaches and associated symptoms such as nausea and vomiting when taken as a prophylactic.

Ingredients

Medicinal ingredient (per 1 softgel): Ubiquinol 100 mg. Non-medicinal ingredients: Medium chain triglycerides (from coconut), purified water, glycerin, gelatin, silica, iron oxide (brown). NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults 19 years and older): Take one (1) softgel per day with food, or as directed by a health care practitioner. For migraine prevention, take one (1) softgel two (2) times per day. Duration of Use: As a migraine preventative, use for a minimum of 3 months to see the beneficial effects.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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