CanPrev TYPE II Collagen Enhanced - UC-II & Boswellin | 60 Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 capsule daily with meals |
| Licensed Natural Health Product | NPN 80125343 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- UC-II UNDENATURED TYPE II COLLAGEN: Each capsule delivers 27.2mg of UC-II, a patented undenatured (non-hydrolyzed) Type II collagen from chicken cartilage, standardized to 4.4%-14.3% unhydrolyzed collagen and 36.8% total collagen.
- BOSWELLIN SUPER BOSWELLIA EXTRACT: Also provides 100mg of Boswellin Super, a Boswellia serrata gum oleoresin extract (14.5:1, equivalent to 1450mg dry oleoresin) standardized to 30% boswellic acid.
- STARTS WORKING IN AS LITTLE AS 7 DAYS: The authorized use of this licensed Natural Health Product (NPN 80125343): starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days.
- SUPPORTS A HEALTHY INFLAMMATORY RESPONSE: May help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response.
- ONE CAPSULE, ONCE DAILY: A convenient once-daily vegetable capsule taken with meals - Non-GMO, gluten-free, dairy-free, and made in Canada by CanPrev, a 60-day supply per bottle.
Product Description
TYPE II Collagen Enhanced - UC-II Undenatured Type II Collagen & Boswellin Super Boswellia Extract
27.2mg of UC-II undenatured Type II collagen (Gallus gallus cartilage) plus 100mg of Boswellin Super Boswellia serrata extract (standardized to 30% boswellic acid) per capsule. Starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days, and may help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response. Once-daily vegetable capsule, 60-day supply. Licensed Natural Health Product. NPN 80125343. Licensed Natural Health Product NPN 80125343.
27,2 mg de collagène de type II non dénaturé UC-II (cartilage, Gallus gallus) et 100 mg d'extrait de Boswellia serrata Boswellin Super (normalisé à 30% d'acide boswellique) par capsule. Commence à aider à réduire la douleur et la raideur articulaires dues à l'arthrose du genou en aussi peu que 7 jours, et peut aider à réduire la douleur articulaire associée à l'arthrose du genou en favorisant une réponse inflammatoire saine. Capsule végétale à prendre une fois par jour, provision de 60 jours. Produit de santé naturel homologué. NPN 80125343.
Two Clinically Studied Actives, Not a Generic Collagen Blend
UC-II undenatured Type II collagen (27.2mg) + Boswellin Super Boswellia serrata extract, 30% boswellic acid (100mg) - Non-GMO, Gluten-Free, once-daily capsule
UC-II: Undenatured, Not Hydrolyzed
Unlike hydrolyzed collagen peptides, UC-II preserves collagen's natural, undenatured structure - the form studied for engaging the body's own joint-supporting response, at a small daily dose of 27.2mg.
Boswellin Super: Standardized to 30% Boswellic Acid
100mg of Boswellia serrata gum oleoresin extract (14.5:1, equivalent to 1450mg of dry oleoresin), standardized to 30% boswellic acid to help support a healthy inflammatory response in the joint.
What's Inside Every Capsule
Here's exactly what each capsule of CanPrev TYPE II Collagen Enhanced delivers.
Reduces Joint Pain & Stiffness From Knee Osteoarthritis
The authorized use of this Natural Health Product (NPN 80125343): starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days.
Promotes a Healthy Inflammatory Response
May help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response in the joint.
Two Actives, One Once-Daily Capsule
27.2mg UC-II undenatured Type II collagen and 100mg Boswellin Super Boswellia extract in a single vegetable capsule taken once daily with meals.
Non-GMO, Gluten-Free, Made in Canada
Formulated and made in Canada, free of gluten and dairy on the label.
CanPrev TYPE II Collagen Enhanced: Supplement Facts
Supplement Facts
- Boswellin Super (Boswellia serrata gum oleoresin, 14.5:1 extract eq. to 1450mg dry oleoresin, std. to 30% boswellic acid) per capsule100 mg
- UC-II (Gallus gallus cartilage, std. to 4.4%-14.3% unhydrolyzed Type II collagen, 36.8% total collagen) per capsule27.2 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Brown rice flour, hypromellose, magnesium stearate, microcrystalline cellulose, potassium chloride.
Recommended Use or Purpose: Starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days. May help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response.
Recommended Dose: Adults (19 years and older) - Take 1 capsule daily with meals, or as directed by a healthcare practitioner. Take a few hours before or after other medications. Duration of Use: Consult a healthcare professional before use exceeding 4 months.
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have liver disease. Take a few hours before or after other medications or natural health products. Consult a health care practitioner for use beyond 4 months. Known Adverse Reactions: May cause mild gastrointestinal disturbances. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Fiche produit
- Boswellin Super (gomme oléorésine de Boswellia serrata, extrait 14,5:1 éq. à 1450 mg d'oléorésine sèche, normalisé à 30% d'acide boswellique) par capsule100 mg
- UC-II (cartilage, Gallus gallus, normalisé à 4,4%-14,3% collagène de type II non hydrolysé, 36,8% collagène) par capsule27.2 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Farine de riz brun, hypromellose, stéarate de magnésium, cellulose microcristalline, chlorure de potassium.
Usage ou fins recommandés : Commence à aider à réduire la douleur et la raideur articulaires dues à l'arthrose du genou en aussi peu que 7 jours. Peut aider à réduire la douleur articulaire associée à l'arthrose du genou en favorisant une réponse inflammatoire saine.
Posologie recommandée : Adultes (19 ans et plus) - Prendre 1 capsule par jour avec les repas, ou selon les directives d'un praticien de soins de santé. Prendre à quelques heures d'intervalle des autres médicaments. Durée d'utilisation : Consultez un professionnel de la santé pour une utilisation de plus de 4 mois.
Mises en garde et précautions : Consultez un praticien de soins de santé avant l'utilisation si vous êtes enceinte, si vous allaitez, ou si vous avez une maladie du foie. Prendre à quelques heures d'intervalle des autres médicaments ou produits de santé naturels. Consultez un praticien de soins de santé pour une utilisation de plus de 4 mois. Réactions indésirables connues : Pourrait causer de légers malaises gastro-intestinaux. Tenir hors de la portée des enfants.
NPN 80125343
Support knee joint comfort in as little as 7 days
Get CanPrev TYPE II Collagen Enhanced on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev TYPE II Collagen Enhanced
Two clinically studied actives - UC-II undenatured Type II collagen and Boswellin Super Boswellia serrata extract - in one once-daily capsule for knee joint support.
UC-II Undenatured Type II Collagen
27.2mg of a patented, undenatured (non-hydrolyzed) Type II collagen from chicken cartilage - a distinct form from hydrolyzed collagen peptides, studied at small daily doses for joint comfort.
Boswellin Super Boswellia Extract
100mg of Boswellia serrata gum oleoresin extract standardized to 30% boswellic acid, to help support a healthy inflammatory response in the joint.
Starts helping in as little as 7 days
The Health Canada-authorized use of this licensed Natural Health Product for knee osteoarthritis joint pain and stiffness.
Licensed, made in Canada
NPN 80125343. Non-GMO, gluten-free, dairy-free, formulated and made in Canada by CanPrev.
Inside every capsule
27.2mg UC-II undenatured Type II collagen (Gallus gallus cartilage) plus 100mg Boswellin Super Boswellia serrata extract (30% boswellic acid), in one vegetable capsule.
How to use it
Take 1 capsule daily with meals
Adults (19 years and older): take one (1) capsule daily with meals, or as directed by a healthcare practitioner.
Space it a few hours from other medications
Take a few hours before or after other medications or natural health products.
One bottle is a 60-day supply
60 vegetable capsules per bottle, at one capsule per day.
Consult a practitioner for use beyond 4 months
Consult a health care practitioner before use exceeding 4 months, and if pregnant, breastfeeding, or living with liver disease.
What the research says about UC-II undenatured Type II collagen and Boswellin Super Boswellia serrata
Educational summaries of published research on undenatured Type II collagen and Boswellia serrata extracts generally; not product-specific claims. CanPrev TYPE II Collagen Enhanced's own claim is the authorized use under NPN 80125343: starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days, and may help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response.
Undenatured Type II collagen outperformed glucosamine and chondroitin over 90 days
In a randomized trial of knee osteoarthritis patients, those given 40mg/day of undenatured Type II collagen (UC-II) saw significantly greater reductions in WOMAC score (-33%), VAS pain (-40%) and Lequesne's functional index (-20%) after 90 days than those given a combination of glucosamine and chondroitin (-14%, -15.4%, -6% respectively).
Human RCT180-day multicenter trial: UC-II reduced WOMAC score significantly more than placebo and glucosamine+chondroitin
In 191 knee osteoarthritis patients randomized to 40mg/day UC-II, glucosamine+chondroitin (1500mg/1200mg), or placebo for 180 days, the UC-II group showed a significantly greater reduction in total WOMAC score than both placebo and glucosamine+chondroitin, including significant improvements on the pain, stiffness and physical function subscales.
Human RCT (multicenter)Review of 8 randomized trials: UC-II consistently improved pain and function scores in early knee osteoarthritis
A systematic review of 8 randomized controlled trials (243 patients) found undenatured Type II collagen supplementation consistently produced better WOMAC and VAS pain outcomes than placebo, with improved walking measurements on timed up-and-go and 6-minute walk tests over 3 to 6 months of use.
Systematic reviewHealthy adults with exercise-related knee pain exercised longer before discomfort began after 120 days of UC-II
In a randomized trial of healthy subjects with exercise-induced knee discomfort but no diagnosed joint disease, 120 days of 40mg/day UC-II significantly improved average knee extension versus placebo and versus baseline, and let participants exercise nearly twice as long before first experiencing joint discomfort.
Human RCT24-week multicenter trial: UC-II improved knee range of motion in adults with activity-related joint discomfort
In 96 healthy adults (20-55 years) who reported knee discomfort on a standardized step-down test, 24 weeks of 40mg/day undenatured Type II collagen produced a statistically significant increase in knee flexion range of motion versus placebo, with the largest gains seen in participants over 35.
Human RCT (multicenter)A different undenatured Type II collagen ingredient also improved knee flexibility and lower-back comfort
In a 12-week randomized trial of healthy Japanese adults, a different undenatured Type II collagen preparation (NEXT-II, not the UC-II used in this product) improved knee passive range of motion, walking and stair-climbing tests, and reduced knee and lower-back discomfort scores versus placebo - independent supporting evidence for the undenatured Type II collagen ingredient category generally.
Human RCTFoundational animal study: undenatured collagen suppressed arthritis, but denatured collagen did not
In the classic mouse model of collagen-induced arthritis, feeding animals small amounts of soluble (undenatured) Type II collagen before immunization suppressed the incidence of arthritis, while feeding denatured Type II collagen had no protective effect - establishing that collagen's natural, undenatured structure is what triggers oral immune tolerance.
Animal studyMechanistic review: oral undenatured collagen engages gut immune tissue to calm joint-directed immune activity
A mechanistic review describes how orally administered undenatured Type II collagen presents its natural epitopes to gut-associated lymphoid tissue (Peyer's patches) in the small intestine, inducing oral tolerance that reduces immune-driven joint inflammation - distinct from hydrolyzed or denatured collagen, which lack this intact epitope structure.
Review + pilot studyMulticenter trial: the lowest oral collagen dose, not the highest, produced the significant clinical response
In a 274-patient, multicenter, placebo-controlled trial of oral Type II collagen in rheumatoid arthritis, the lowest tested dose (20 micrograms/day) produced a statistically significant response rate versus placebo, consistent with the low-dose oral tolerance mechanism by which small amounts of orally administered collagen preferentially induce disease-suppressing regulatory cells.
Human RCT (multicenter)Boswellin Super improved knee osteoarthritis pain within 5 days in a 90-day placebo-controlled trial
In 105 knee osteoarthritis patients randomized to placebo or Boswellin Super (a Boswellia serrata extract standardized to 30% boswellic acid) at 150mg or 300mg twice daily, pain scores improved as early as day 5, with VAS pain reduced by 45-62% and total WOMAC score improved by 68-74% by day 90, alongside reductions in the inflammatory markers TNF-alpha, hs-CRP and IL-6.
Human RCT120-day trial: a Boswellin Boswellia serrata extract improved knee joint space and reduced bone spurs on X-ray
In a placebo-controlled trial of knee osteoarthritis patients given a standardized Boswellin Boswellia serrata extract for 120 days - longer than most prior Boswellia trials - radiographic assessment showed improved knee joint space and reduced osteophytes, alongside significantly reduced pain, stiffness and serum hs-CRP versus placebo.
Human RCT (pilot)Classic crossover trial: Boswellia serrata extract reduced knee pain and swelling versus placebo
In a randomized, double-blind, placebo-controlled crossover trial, 8 weeks of Boswellia serrata extract decreased knee pain, increased knee flexion and increased walking distance versus placebo, with reduced frequency of knee swelling; the extract was well tolerated aside from minor gastrointestinal effects.
Human RCT (crossover)90-day trial: a standardized Boswellia extract improved pain and function as early as 7 days
In 70 knee osteoarthritis patients given 100mg or 250mg daily of a Boswellia serrata extract standardized to 30% boswellic acid, both doses produced clinically and statistically significant improvements in pain and physical function scores, with the higher dose showing benefit within 7 days, alongside a significant reduction in the cartilage-degrading enzyme MMP-3 in joint fluid.
Human RCTHead-to-head trial: two standardized Boswellia extracts both reduced knee osteoarthritis pain versus placebo
Comparing two enriched Boswellia serrata extracts at 100mg/day over 90 days, both significantly improved pain and physical function scores versus placebo, with one formulation showing benefit as early as day 7; safety parameters were similar across all three groups.
Human RCT30-day trial: a Boswellia extract reduced knee pain scores and inflammatory blood biomarkers
In a 30-day placebo-controlled trial of knee osteoarthritis patients, a standardized Boswellia serrata gum resin extract significantly reduced VAS pain, WOMAC and Lequesne scores as early as day 5, alongside reductions in circulating inflammatory and cartilage-breakdown markers (MMP-3, TNF-alpha, hs-CRP, and collagen Type II cleavage product).
Human RCTPharmacokinetic review: boswellic acids act on multiple anti-inflammatory targets, not just one enzyme
A comprehensive review of Boswellia serrata's pharmacology found that beyond the originally proposed 5-lipoxygenase inhibition, boswellic acids reach plasma concentrations sufficient to inhibit microsomal prostaglandin E synthase-1 and the enzyme cathepsin G - a fuller picture of how the extract exerts its anti-inflammatory effect in the body.
ReviewBoswellic acids reduced inflammation across multiple animal models via leukotriene inhibition
Testing boswellic acids across several standard inflammation models (mouse ear edema, rat paw edema, developing arthritis), researchers confirmed anti-inflammatory activity consistent with inhibition of 5-lipoxygenase, the key enzyme that produces pro-inflammatory leukotrienes, whether the extract was applied topically or taken systemically.
Animal studyReview: boswellic acids lower several pro-inflammatory cytokines that drive tissue breakdown
A review of boswellic acids' role in chronic inflammatory disease describes how they decrease production of pro-inflammatory cytokines including IL-1, IL-2, IL-6, interferon-gamma and TNF-alpha - signaling molecules that, left unchecked, are directed at destroying tissues such as joint cartilage.
ReviewLaboratory study: a Boswellia extract protected cartilage cells from inflammatory damage
Exposing human cartilage cells to the inflammatory signal IL-1beta, researchers found a Boswellia serrata extract protected the cells from inflammation-induced death, improved their production of cartilage-building glycosaminoglycans, and inhibited the cartilage-degrading enzyme MMP-3 in inflamed synovial cells.
Laboratory study4-week trial: a Boswellia serrata extract reduced knee osteoarthritis pain and improved function
In a randomized, double-blind, placebo-controlled trial, an oily solution of Boswellia serrata (frankincense) extract applied to the affected knee three times daily for four weeks produced significantly greater reductions in WOMAC, VAS pain and patient global assessment scores than placebo.
Human RCTA boswellic-acid-containing supplement added extra benefit on top of physical therapy for knee osteoarthritis
In a three-arm trial, knee osteoarthritis patients combining physical therapy with a supplement containing boswellic acid and harpagoside (a different multi-ingredient product, not Boswellin Super) saw about twice the functional improvement of physical therapy alone, and were three times more likely to reach a clinically meaningful quality-of-life improvement.
Human RCT (multicenter)Meta-analysis of 545 patients: Boswellia extract relieved pain and improved joint function versus control
Pooling data from 7 randomized controlled trials of 545 osteoarthritis patients, Boswellia serrata and its extracts significantly reduced VAS pain and WOMAC pain and stiffness scores, and improved WOMAC function and Lequesne index scores, compared with placebo or standard treatment.
Meta-analysisCochrane review: enriched Boswellia serrata extract is among the few herbal osteoarthritis treatments with high-quality supporting evidence
A Cochrane systematic review of 49 randomized trials of oral herbal osteoarthritis treatments found high-quality evidence that 90 days of a 100mg enriched Boswellia serrata extract meaningfully reduced pain and improved physical function versus placebo, with moderate-quality evidence of fewer adverse events than placebo.
Systematic review (Cochrane)Review: boswellic acids show pilot evidence across several inflammatory conditions with a favorable safety profile
A review of boswellic acids' pharmacology found their principal mechanism to be inhibition of 5-lipoxygenase, with additional effects on inflammatory cytokines and the complement system, and noted pilot clinical evidence of benefit in several chronic inflammatory conditions with a favorable side-effect profile compared to conventional anti-inflammatory drugs.
ReviewFrequently asked questions
What is CanPrev TYPE II Collagen Enhanced and what does it do?
It's a once-daily vegetable capsule providing 27.2mg of UC-II undenatured Type II collagen and 100mg of Boswellin Super Boswellia serrata extract. It starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days, and may help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response.
How much do I take?
Adults 19 years and older take 1 capsule daily with meals, or as directed by a healthcare practitioner. Take a few hours before or after other medications. Consult a healthcare professional before use exceeding 4 months.
What is UC-II and how is it different from hydrolyzed collagen?
UC-II is a patented, undenatured (non-hydrolyzed) Type II collagen sourced from chicken cartilage. Unlike hydrolyzed collagen peptides (broken down into smaller fragments), UC-II preserves collagen's natural structure, which is the form studied for joint comfort at small daily doses.
What is Boswellin Super?
Boswellin Super is a standardized Boswellia serrata gum oleoresin extract (14.5:1, equivalent to 1450mg of dry oleoresin) standardized to 30% boswellic acid, included to help support a healthy inflammatory response in the joint.
Is this the same as CanPrev's other collagen products?
No. CanPrev's collagen powders and liquids (Collagen Beauty, Collagen Joint & Cartilage, Collagen Full Spectrum) use hydrolyzed Type I & III collagen peptides for skin, hair and general connective tissue. This product is different: it uses undenatured (non-hydrolyzed) Type II collagen (UC-II) specifically studied for joint cartilage, combined with Boswellin Super Boswellia extract.
Are there any cautions?
Consult a health care practitioner before use if you are pregnant, breastfeeding, or have liver disease. May cause mild gastrointestinal disturbances. Take a few hours before or after other medications. Keep out of reach of children.
How long does one bottle last?
Each bottle contains 60 vegetable capsules - a 60-day supply at 1 capsule per day.
Is it Non-GMO and gluten-free?
Yes - the label indicates Non-GMO, gluten-free and dairy-free, formulated and made in Canada.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support knee joint comfort in as little as 7 days
Get CanPrev TYPE II Collagen Enhanced on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80125343. Starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days. May help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response. The research summaries below concern UC-II undenatured Type II collagen and Boswellia serrata generally and are educational - they are not claims about this finished product. Consult a health care practitioner prior to use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have liver disease. Take a few hours before or after other medications or natural health products. Consult a health care practitioner for use beyond 4 months. Known Adverse Reactions: May cause mild gastrointestinal disturbances. Keep out of reach of children.
Indications
Recommended Use or Purpose: Starts to help reduce joint pain and stiffness due to osteoarthritis of the knee in as little as 7 days. May help reduce joint pain associated with osteoarthritis of the knee by promoting a healthy inflammatory response.
Ingredients
Medicinal Ingredients (per capsule): Boswellin Super (Boswellia serrata gum oleoresin, 14.5:1 extract equivalent to 1450mg dry oleoresin, standardized to 30% boswellic acid) 100mg; UC-II (Gallus gallus cartilage, standardized to 4.4%-14.3% unhydrolyzed Type II collagen and 36.8% total collagen) 27.2mg. Non-medicinal ingredients: Brown rice flour, hypromellose, magnesium stearate, microcrystalline cellulose, potassium chloride. Non-medicinal ingredients are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose: Adults (19 years and older) - Take 1 capsule daily with meals, or as directed by a healthcare practitioner. Take a few hours before or after other medications. Duration of Use: Consult a healthcare professional before use exceeding 4 months.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.