CanPrev Synergy C - Buffered Vitamin C Complex | 90 V-Caps
Visit the CanPrev Store| Brand | CanPrev |
| Serving | 2 capsules per day, with food |
| Licensed Natural Health Product | NPN 80075509 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- BUFFERED, GENTLE VITAMIN C: 1000mg of vitamin C daily from a blend of four buffered mineral ascorbates - magnesium, calcium, sodium and potassium ascorbate - a pH-neutral form of vitamin C.
- PROVIDES ANTIOXIDANTS FOR THE MAINTENANCE OF GOOD HEALTH: Vitamin C is a source of antioxidants that helps protect cells against free radicals and supports the maintenance of good health.
- WITH CITRUS BIOFLAVONOIDS: 150mg of citrus bioflavonoids (Citrus sinensis fruit) per capsule - naturally found alongside vitamin C in citrus fruit.
- PLUS SEA BUCKTHORN, RUTIN & ZINC: 125mg sea buckthorn pulp extract (4:1), 25mg rutin (quercetin-3-rutinoside) and 625mcg zinc (zinc citrate) per capsule, for a complete synergy formula.
- 90 VEGETABLE CAPSULES, 45-DAY SUPPLY: At the label dose of 2 capsules per day, with food.
- VEGAN, MADE WITHOUT ARTIFICIAL INGREDIENTS: Vegan and non-GMO, with no binders or fillers, and no gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives, or animal products.
Product Description
Synergy C - Buffered Vitamin C Complex
CanPrev Synergy C is a broad-spectrum vitamin C complex providing 1000mg of vitamin C daily from a blend of four gentle, buffered mineral ascorbates (magnesium, calcium, sodium and potassium ascorbate). It is enhanced with citrus bioflavonoids and rutin, and includes zinc citrate and sea buckthorn extract - a fruit naturally rich in vitamin C - for a complete synergy formula. Comes in an easy-to-swallow vegetable capsule with only essential active ingredients - no binders or fillers. Licensed Natural Health Product, NPN 80075509. Provides antioxidants for the maintenance of good health. Licensed Natural Health Product NPN 80075509.
CanPrev Synergy C est un complexe de vitamine C à large spectre qui fournit 1000 mg de vitamine C par jour, dérivée d'un mélange de quatre ascorbates minéraux tamponnés et doux (magnésium, calcium, sodium et potassium). Il est enrichi de bioflavonoïdes d'agrumes et de rutine, et comprend du citrate de zinc et de l'extrait d'argousier - un fruit naturellement riche en vitamine C - pour une formule synergique complète. Se présente en capsule végétale facile à avaler, ne contenant que des ingrédients actifs essentiels, sans agents liants ni de remplissage. Produit de santé naturel homologué, NPN 80075509. Fournit des antioxydants pour le maintien d'une bonne santé.
A Buffered, Complete Vitamin C Synergy Formula
500mg Buffered Vitamin C + Citrus Bioflavonoids, Sea Buckthorn, Rutin & Zinc per Capsule - Vegan, Non-GMO, Gluten-Free
Buffered Mineral Ascorbates, Not Plain Ascorbic Acid
Vitamin C from a blend of four mineral ascorbates - magnesium, calcium, sodium and potassium ascorbate - for a gentler, pH-neutral form of vitamin C.
A Complete Synergy Formula
Citrus bioflavonoids, sea buckthorn extract, rutin and zinc citrate alongside vitamin C in every capsule - no binders or fillers.
Advanced Ingredients, Superior Results
Synergy C combines vitamin C with citrus bioflavonoids, sea buckthorn, rutin and zinc in a single buffered formula. Here's what's actually in every capsule.
Vitamin C (Buffered Mineral Ascorbates)
A blend of four mineral ascorbates - magnesium, calcium, sodium and potassium ascorbate - providing 1000mg of vitamin C per day at the label dose of 2 capsules.
500mg per capsuleCitrus Bioflavonoids
From Citrus sinensis fruit, naturally found alongside vitamin C in citrus fruit.
150mg per capsuleSea Buckthorn Extract
From Hippophae rhamnoides fruit, a berry naturally rich in vitamin C and other nutrients.
125mg per capsule (4:1)
Rutin
Quercetin-3-rutinoside, a citrus-derived flavonoid glycoside.
25mg per capsuleZinc (Zinc Citrate)
An essential trace mineral included alongside the vitamin C and bioflavonoid blend.
625mcg per capsuleCanPrev Synergy C: Supplement Facts
Medicinal Ingredients (per capsule)
- Vitamin C (from a blend of 4 mineral ascorbates: magnesium, calcium, sodium and potassium ascorbate) per capsule500 mg
- Citrus bioflavonoids (Citrus sinensis fruit) per capsule150 mg
- Sea buckthorn extract (Hippophae rhamnoides fruit, 4:1) per capsule125 mg
- Rutin (quercetin-3-rutinoside) per capsule25 mg
- Zinc (zinc citrate) per capsule625 mcg
Non-Medicinal Ingredients: Non-medicinal ingredients: Vegetable-grade magnesium stearate, vegetable capsule.
Recommended Use or Purpose: Provides antioxidants for the maintenance of good health.
Recommended Dose (Adults 19 years and older): Take 2 capsules per day with food, or as directed by a healthcare practitioner. Take a few hours before or after taking other medications.
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use, especially if pregnant or breastfeeding, or if taking any prescription medications, as citrus bioflavonoids may alter the effectiveness of these medications. Do not use if the safety seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Formulated and made in Canada for CanPrev Natural Health Products Ltd., 70 North Wind Place, Toronto, ON, Canada M1S 3R5. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Ingrédients médicinaux (par capsule)
- Vitamine C (dérivée d'un mélange de 4 ascorbates minéraux : ascorbate de magnésium, de calcium, de sodium et de potassium) par capsule500 mg
- Bioflavonoïdes d'agrumes (fruit de Citrus sinensis) par capsule150 mg
- Extrait d'argousier (fruit d'Hippophae rhamnoides, 4:1) par capsule125 mg
- Rutine (quercétine-3-rutinoside) par capsule25 mg
- Zinc (citrate de zinc) par capsule625 mcg
Ingrédients non médicinaux : Ingrédients non médicinaux : Stéarate de magnésium de grade végétal, capsule végétale.
Usage ou fins recommandés : Fournit des antioxydants pour le maintien d'une bonne santé.
Posologie recommandée (adultes de 19 ans et plus) : Prendre deux (2) capsules avec de la nourriture par jour, ou selon les directives d'un praticien de soins de santé. Prendre quelques heures avant ou après la prise d'autres médicaments.
Mises en garde et avertissements : Comme pour tout produit de santé naturel, vous devez consulter un praticien de soins de santé avant d'en faire l'usage, surtout si vous êtes enceinte ou allaitante, ou si vous prenez tout médicament de prescription, car les bioflavonoïdes d'agrumes pourraient altérer l'efficacité de ces médicaments. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de portée des enfants.
NPN 80075509
Add CanPrev Synergy C to your daily routine
Get CanPrev Synergy C on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Synergy C
A buffered vitamin C complex with citrus bioflavonoids, sea buckthorn, rutin and zinc - complete CanPrev quality.
Buffered mineral ascorbates, not plain ascorbic acid
Vitamin C from a blend of magnesium, calcium, sodium and potassium ascorbate - a gentler, pH-neutral form of vitamin C.
1000mg vitamin C daily, a simple 2-capsule dose
500mg of buffered vitamin C per capsule - take 2 capsules per day with food for a full 1000mg daily dose.
A complete synergy formula
Citrus bioflavonoids, sea buckthorn extract, rutin and zinc citrate alongside the vitamin C in every capsule.
Trusted Canadian brand
CanPrev - a licensed Natural Health Product, NPN 80075509, formulated and made in Canada.
Inside every capsule
500mg of buffered vitamin C (from four mineral ascorbates) plus citrus bioflavonoids, sea buckthorn extract, rutin and zinc citrate - 1000mg of vitamin C daily at the label dose of 2 capsules.
How to use it
Take 2 capsules per day with food
Adults (19 years and older): take 2 capsules per day with food, or as directed by a healthcare practitioner.
Space it apart from other medications
Take a few hours before or after taking other medications.
Store safely
Keep out of reach of children. Do not use if the safety seal is broken.
Use daily for a 45-day supply
Each bottle of 90 capsules provides a 45-day supply at the label dose of 2 capsules per day.
What the research says about vitamin C, citrus bioflavonoids, sea buckthorn, rutin and zinc
Educational summaries of published research on this formula's ingredients generally - these are not product-specific claims. CanPrev Synergy C's own claim is the authorized use under NPN 80075509: providing antioxidants for the maintenance of good health.
Vitamin C supports both innate and adaptive immune defenses
A review of vitamin C's immune roles found it accumulates in neutrophils to enhance chemotaxis and microbial killing, and also supports the proliferation and differentiation of B- and T-cells, contributing to both innate and adaptive immunity.
ReviewA 29-comparison meta-analysis found regular vitamin C shortened colds by 8%
A Cochrane meta-analysis of 29 trial comparisons (11,306 participants) found regular vitamin C supplementation did not reduce cold incidence in the general population, but reduced the duration of colds by about 8% in adults and 14% in children, and cut cold incidence by 52% in people under brief periods of extreme physical stress, such as marathon runners and soldiers.
Meta-analysisA combined vitamin C plus zinc trial reduced cold symptom duration
Pooled analysis of two double-blind, randomized, placebo-controlled trials (94 patients) found a combination of 1000mg vitamin C plus 10mg zinc was significantly more effective than placebo at reducing rhinorrhoea duration over 5 days of treatment, with quicker symptom relief and good tolerability.
Pooled RCT analysisA systematic review found buffered calcium ascorbate forms improved tolerability over plain ascorbic acid
A systematic review of 13 studies in healthy adults found calcium ascorbate combined with vitamin C metabolites showed better tolerability and fewer epigastric adverse events than plain ascorbic acid, along with favourable effects on leukocyte and plasma vitamin C concentrations relevant to immune function.
Systematic reviewBuffering with ascorbic acid reduced gastric irritation in a human trial
A randomized crossover trial in 17 healthy subjects found a buffered formulation combined with ascorbic acid produced the lowest endoscopic mucosal lesion score and the least gastric microbleeding among the tested formulations, confirming that buffering can meaningfully improve gastric tolerability.
Human RCTA landmark dose-response study mapped how much vitamin C the body actually absorbs and uses
A depletion-repletion study in seven healthy volunteers found vitamin C plasma concentrations followed a sigmoid dose-response curve, with complete plasma saturation at 1000mg per day and bioavailability declining at single doses of 500mg and higher - informing why a moderate, evenly-split daily dose is efficiently absorbed.
Human studyA citrus extract was found more bioavailable than synthetic vitamin C alone
A comparative bioavailability study found a natural citrus extract containing bioflavonoids was 35% more absorbed than synthetic ascorbic acid alone, based on the area under the plasma concentration-time curve after a single 500mg ascorbate dose.
Human studyFindings on how flavonoids affect vitamin C absorption have been mixed
A review of vitamin C in citrus juices notes that findings on flavonoid effects on vitamin C bioavailability are mixed - some studies show flavonoids inhibit intestinal absorption, while others found vitamin C from whole citrus extract was more available than synthetic ascorbic acid alone.
ReviewA citrus flavanone's carotenoid-boosting effect was reduced when ascorbic acid was added
In a Caco-2 intestinal cell model, hesperidin and hesperetin increased carotenoid uptake by 60-70%, but adding ascorbic acid significantly reduced this enhancing effect - an honest, disclosed finding showing citrus compounds can interact in complex, sometimes competing ways.
In vitro studyA meta-analysis found sea buckthorn supplementation improved lipid profiles
A systematic review and meta-analysis of 15 randomized controlled trials found sea buckthorn supplementation reduced triglycerides, total cholesterol and LDL cholesterol, and increased HDL cholesterol, though effects were seen mainly in people with abnormal lipid metabolism, with no effect on blood sugar, blood pressure or BMI overall.
Meta-analysisSea buckthorn oil showed no significant effect on oxidative stress in hemodialysis patients
A double-blinded, randomized crossover study in 45 hemodialysis patients found 8 weeks of sea buckthorn oil supplementation produced no significant change in DNA damage, oxidative stress markers, salivary flow, or inflammation compared to placebo - an honest, disclosed null finding in this specific patient population.
Human RCTSea buckthorn oil showed a beneficial trend on vaginal mucosal integrity in a placebo-controlled trial
A randomized, double-blind, placebo-controlled study of 116 postmenopausal women found oral sea buckthorn oil supplementation was associated with significantly better improvement in vaginal epithelial integrity compared to placebo over three months.
Human RCTA review found rutin among flavonoids showing antihypertensive potential
A comprehensive review of flavonoids including rutin found they mitigate oxidative stress, enhance endothelial function by promoting nitric oxide bioavailability, and modulate vasoactive factors involved in blood pressure regulation in preclinical hypertension models.
ReviewRutin improved vascular endothelial function in obese rats on a high-fat diet
In Wistar rats fed a high-fat diet, rutin treatment (50 and 100mg/kg) improved obesity-related vascular endothelial dysfunction and lipid profile compared to untreated obese controls, in an ex-vivo aorta reactivity study.
Animal studyRutin reduced vascular injury and inflammation in a rat model of vasculitis
In a rat model of Henoch-Schonlein purpura (IgA vasculitis), rutin significantly alleviated skin purpura, renal injury and systemic inflammation, and ameliorated vascular endothelial injury by modulating nitric oxide, endothelin-1 and vascular endothelial growth factor.
Animal studyA 2024 Cochrane review found zinc may shorten cold duration but adds mild side effects
A Cochrane review of 34 trials (8,526 participants) found zinc supplementation had little or no effect on preventing colds, but when used for treatment there may be a reduction in mean cold duration of about 2.4 days, alongside a probable increase in non-serious adverse events such as bad taste and nausea.
Cochrane reviewA systematic review found zinc reduced cold duration by over two days
A systematic review of 20 randomized controlled trials on single micronutrients found zinc supplementation - unlike vitamin D, A or E given alone - was associated with a reduction in common cold duration of about 2.25 days among healthy adults.
Systematic reviewVitamin C and zinc both support components of the immune system
A mechanistic review describes how vitamin C supplementation improves antimicrobial and natural killer cell activity, lymphocyte proliferation and chemotaxis, while zinc undernutrition impairs phagocytosis and natural killer cell activity - concluding that adequate intake of both nutrients helps reduce the risk, severity and duration of respiratory infections.
ReviewA meta-analysis found combined vitamin C and E reduced oxidative stress biomarkers
A GRADE-assessed meta-analysis of 17 randomized controlled trials (965 participants) found combined vitamin C and E supplementation significantly reduced malondialdehyde and lipid peroxidation markers, and increased total antioxidant capacity, compared to control.
Meta-analysisA human trial directly measured vitamin C's dose-dependent free-radical quenching in blood plasma
Using electron paramagnetic resonance spectroscopy in a double-blind, placebo-controlled crossover pilot study, researchers found the proportion of reactive oxygen species in blood plasma samples was reduced in direct proportion to the amount of vitamin C ingested by participants.
Human studyCombined vitamin C and E did not improve endothelial function in a small trial of adolescents with type 1 diabetes
A six-week open-label trial in 9 adolescents with type 1 diabetes found combined vitamin C and E supplementation produced no significant change in endothelial function, inflammatory markers, or antioxidant capacity - an honest, disclosed null finding in this specific population.
Clinical trialA 2025 market analysis found most vitamin C supplements exceed recommended daily doses
An analysis of 106 vitamin C supplements sold in Germany and the USA found more than three-quarters exceeded the recommended daily dose and nearly 40% exceeded a potential upper safety level, while noting that adverse effects of even high doses are rare in the healthy general public, though caution is advised for those with limited kidney function or a prior history of kidney stones.
Market analysisHigh-dose vitamin C supplements were linked to higher kidney stone risk - in men
A prospective cohort of over 196,000 men and women found total and supplemental vitamin C intake of 1,000mg per day or more was associated with significantly higher risk of incident kidney stones in men, but showed no such association in women.
Prospective cohortSwedish men taking ascorbic acid supplements had roughly double the kidney stone rate
A prospective study of Swedish men found those who regularly used ascorbic acid supplements had about twice the incidence of kidney stones compared with non-users, adding to evidence that very high-dose vitamin C warrants caution in men prone to stones.
Prospective cohortFrequently asked questions
What is CanPrev Synergy C and what does it do?
It's a vegetable capsule supplement providing 500mg of buffered vitamin C (from a blend of four mineral ascorbates) plus citrus bioflavonoids, sea buckthorn extract, rutin and zinc citrate per capsule - 1000mg of vitamin C daily at the label dose. Its Health Canada-authorized use is providing antioxidants for the maintenance of good health.
How do I take it?
Adults (19 years and older): take 2 capsules per day with food, or as directed by a healthcare practitioner. Take a few hours before or after taking other medications.
What makes this a 'buffered' vitamin C?
The vitamin C is bound to minerals - magnesium, calcium, sodium and potassium ascorbate - instead of being plain ascorbic acid, giving a pH-neutral form of vitamin C.
Why does it include citrus bioflavonoids, sea buckthorn, rutin and zinc?
Citrus bioflavonoids (150mg) and rutin (25mg) are flavonoids naturally found alongside vitamin C in citrus fruit; sea buckthorn extract (125mg, 4:1) is from a berry naturally rich in vitamin C; zinc citrate (625mcg) is an essential trace mineral included in the same capsule.
Is it vegan and allergen-friendly?
Yes - vegan and non-GMO, with no binders or fillers, and no gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives, or animal products.
Who should not use it?
Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you are taking any prescription medications, as citrus bioflavonoids may alter the effectiveness of these medications. Do not use if the safety seal is broken. Keep out of reach of children.
How long does one bottle last?
Each bottle of 90 vegetable capsules provides a 45-day supply at the label dose of 2 capsules per day.
Where is it made?
CanPrev Synergy C is formulated and made in Canada for CanPrev Natural Health Products Ltd. (Toronto, ON, Canada), and is a licensed Natural Health Product under NPN 80075509.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Add CanPrev Synergy C to your daily routine
Get CanPrev Synergy C on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80075509. Provides antioxidants for the maintenance of good health. The research summaries below concern the ingredients vitamin C, citrus bioflavonoids, sea buckthorn, rutin and zinc generally, and are educational - they are not claims about this finished product. Consult a health care practitioner prior to use, especially if pregnant or breastfeeding, or if taking any prescription medications, as citrus bioflavonoids may alter the effectiveness of these medications. Do not use if the safety seal is broken. Keep out of reach of children. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use, especially if pregnant or breastfeeding, or if taking any prescription medications, as citrus bioflavonoids may alter the effectiveness of these medications. Do not use if the safety seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Provides antioxidants for the maintenance of good health.
Ingredients
Medicinal Ingredients (1 capsule): Vitamin C (from a blend of four mineral ascorbates - magnesium ascorbate, calcium ascorbate, sodium ascorbate and potassium ascorbate) 500mg. Citrus bioflavonoids (Citrus sinensis fruit) 150mg. Sea buckthorn extract (Hippophae rhamnoides fruit, 4:1) 125mg. Rutin (quercetin-3-rutinoside) 25mg. Zinc (zinc citrate) 625mcg. Non-medicinal ingredients: Vegetable-grade magnesium stearate, vegetable capsule. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults 19 years and older): Take 2 capsules per day with food, or as directed by a healthcare practitioner. Take a few hours before or after taking other medications.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Formulated and made in Canada for CanPrev Natural Health Products Ltd., 70 North Wind Place, Toronto, ON, Canada M1S 3R5. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.