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Health Canada NPN 80101190 500mg Pure Quercetin per Capsule Vegan · Non-GMO · Gluten-Free 120 V-Caps · 120-Day Supply
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CanPrev Quercetin Supplement - Antioxidant & Capillary Support | 120 V-Caps

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BrandCanPrev
Serving1-2 capsules daily - 500mg Quercetin per capsule
Licensed Natural Health ProductNPN 80101190
Quality StandardsGMP-compliant facility
CountryFormulated in Canada Formulated in Canada

About this item

  • 500MG PURE QUERCETIN: Each vegetable capsule provides 500mg of quercetin naturally sourced from the flower bud of the Japanese pagoda tree (Styphnolobium japonicum).
  • ANTIOXIDANT SUPPORT: Provides antioxidants and is used in Herbal Medicine as a capillary/blood vessel protectant, supporting healthy circulation.
  • SEASONAL COMFORT: A popular choice for comfort during seasonal changes, alongside its core antioxidant and circulatory benefits.
  • SIMPLE DAILY DOSE: Take 1 capsule, 1 to 2 times per day with food - a 120-day supply in every bottle at the minimum dose.
  • CLEAN, VEGAN FORMULA: Vegan, non-GMO, gluten-free, dairy-free and soy-free, with only one non-medicinal ingredient (hypromellose, the vegetable capsule shell) and no fillers or binders.
  • TRUSTED CANADIAN BRAND: Formulated by CanPrev, a Health Canada-licensed natural health product company. NPN 80101190.

Customer Reviews

4.7 out of 5 · 225 global ratings
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Product Description

Quercetin 500mg - Pure Antioxidant & Circulation Support

CanPrev Quercetin Capsules

500mg of pure quercetin (quercetin dihydrate, a flavonoid naturally sourced from the flower bud of the Japanese pagoda tree, Styphnolobium japonicum) in a single vegetable capsule, with no fillers or binders. Provides antioxidants, and is used in Herbal Medicine as a capillary/blood vessel protectant to support healthy circulation. Licensed Natural Health Product. Licensed Natural Health Product NPN 80101190.

500 mg de quercétine pure (un flavonoïde sous forme de quercétine dihydraté, provenant naturellement du bouton floral de l'arbre pagode du Japon, Styphnolobium japonicum) dans une seule capsule végétale, sans charges ni liants. Fournit des antioxydants et est utilisé en médecine herbale comme protecteur des capillaires/vaisseaux sanguins pour soutenir une circulation saine. Produit de santé naturel homologué. NPN 80101190.

Quercetin Capsules lifestyle
CanPrev Quercetin Capsules
500mg Pure Quercetin · Capillary/Vessel Protectant

Pure Quercetin, Nothing Else

500mg Quercetin per Capsule - No Fillers, No Binders - Vegan, Non-GMO, Gluten-Free

500mg Pure Quercetin per Capsule

Each vegetable capsule delivers 500mg of quercetin naturally sourced from the flower bud of the Japanese pagoda tree - no fillers or binders added.

Capillary & Blood Vessel Support

Provides antioxidants and is used in Herbal Medicine as a capillary/blood vessel protectant, supporting the body's circulatory health.

Why Quercetin

Quercetin is one of the most-studied plant flavonoids - explored for its antioxidant activity, its role in supporting healthy blood vessels, and its effects on mast cells and histamine pathways. Here is what the wider research on quercetin explores.

Antioxidant Support

Provides antioxidants that help protect cells against the effects of free radicals.

Capillary/Blood Vessel Protectant

Used in Herbal Medicine as a capillary/blood vessel protectant, supporting healthy circulation.

No Fillers, No Binders

A clean single-ingredient formula - just 500mg of quercetin and a vegetable capsule shell (hypromellose).

Vegan, Easy-to-Swallow Capsule

A vegetable capsule format that's vegan, non-GMO and gluten-free, with a simple once- or twice-daily dose.

CanPrev Quercetin Capsules: Supplement Facts

CanPrev™Quercetin Capsules
English

Product Facts

  • Quercetin (flower bud, Styphnolobium japonicum) per capsule500 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose (vegetable capsule shell).

Recommended Use or Purpose: Provides antioxidants. Used in Herbal Medicine as a capillary/blood vessel protectant.

Recommended Dose (Adults): Take 1 capsule, 1 to 2 times per day with food, or as directed by a health care practitioner. Duration of Use: For use beyond 12 weeks, consult a health care practitioner.

Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Keep out of reach of children. Do not use if safety seal is broken.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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Info-produit

  • Quercétine (bouton floral, Styphnolobium japonicum) par capsule500 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose (enveloppe de capsule végétale).

Usage ou fins recommandés : Fournit des antioxydants. Utilisé en médecine herbale comme protecteur des capillaires/vaisseaux sanguins.

Posologie recommandée (adultes) : Prendre 1 capsule, 1 à 2 fois par jour avec de la nourriture, ou selon les directives d'un praticien de soins de santé. Durée d'utilisation : Consulter un praticien de soins de santé pour un usage de plus de 12 semaines.

Mises en garde : Consulter un praticien de soins de santé avant d'en faire l'usage si vous êtes enceinte ou vous allaitez. Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.

NPN 80101190

500mg Pure Quercetin · VeganCapillary & Blood Vessel Support120 V-Caps · 120-Day SupplyNon-GMO · Gluten-Free · Formulated in Canada

Support antioxidant and circulation health with quercetin

Get CanPrev Quercetin 500mg on Amazon.ca - fast, protected delivery.

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Why CanPrev Quercetin

500mg of pure quercetin per capsule, with no fillers or binders - premium CanPrev quality.

Pure 500mg dose

Each vegetable capsule provides 500mg of quercetin naturally sourced from the flower bud of the Japanese pagoda tree - no fillers or binders.

Provides antioxidants

An antioxidant used in Herbal Medicine as a capillary/blood vessel protectant, supporting healthy circulation.

Simple once- or twice-daily dose

Take 1 capsule, 1 to 2 times per day with food - a 120-day supply in every bottle at the minimum dose.

Vegan, clean-label brand

CanPrev - vegan, non-GMO, gluten-free formula, formulated in Canada. NPN 80101190.

How to use it

Take 1 capsule, 1-2 times daily with food

Adults: take one (1) capsule, one (1) to two (2) times per day with food, or as directed by a health care practitioner.

A 120-day supply at the minimum dose

Each bottle of 120 vegetable capsules provides up to a 120-day supply at 1 capsule daily, or a 60-day supply at 2 capsules daily.

Ask a practitioner before 12 weeks' continuous use

Ask a health care practitioner before using for more than 12 weeks.

Store safely

Keep out of reach of children, and do not use if the bottle's safety seal is broken.

What the research says about quercetin

Educational summaries of published research on quercetin generally; not product-specific claims. CanPrev Quercetin 500mg's own authorized use under NPN 80101190 is that it provides antioxidants and is used in Herbal Medicine as a capillary/blood vessel protectant.

Absorption & Bioavailability

A 500mg quercetin dose was compared across three oral delivery forms

In 18 healthy adults given 500mg of quercetin as a suspension, a nutritional bar, or a chewable form, blood levels were measurable within hours for all three, though peak concentration and timing varied - one of the first comprehensive human studies of quercetin absorption at supplement-typical doses.

Human PK study
Kaushik et al., Journal of Food Science (2012)
Absorption & Bioavailability

Daily quercetin capsules raised plasma quercetin 23-fold over 28 days

In a double-blind study, healthy adults taking 1.0g/day of quercetin in capsule form for 28 days saw plasma quercetin concentrations rise roughly 23-fold versus placebo, confirming reliable absorption from a capsule format, though several heart-disease risk markers were unchanged.

Human RCT
Conquer et al., Journal of Nutrition (1998)
Absorption & Bioavailability

A review maps why flavonoids like quercetin need delivery-system support

A pharmacology review describes quercetin and related flavonoids as poorly water-soluble and rapidly metabolized in the body, and surveys nanoparticle- and lipid-based delivery systems designed to protect them from degradation and improve oral absorption.

Review
Leonarduzzi et al., Current Medicinal Chemistry (2010)
Antioxidant Mechanism

A review describes quercetin activating the cell's own antioxidant pathway

A 2026 review describes quercetin activating the Sirt1/Nrf2/HO-1 signaling pathway and restoring the antioxidant enzymes SOD, catalase and glutathione peroxidase in preclinical models of oxidative stress - one proposed mechanism behind its broader antioxidant activity.

Review
Yazdanpanah et al., Journal of Biochemical and Molecular Toxicology (2026)
Antioxidant Mechanism

Quercetin was one of several natural flavonols tested for antioxidant potency

Researchers compared several natural flavonols and flavones, including quercetin, for antioxidant and vasorelaxant activity in rat aorta - a synthetic reference compound outperformed all the natural compounds tested, including quercetin, in blocking superoxide radical generation.

Preclinical study
Woodman & Chan, Clinical and Experimental Pharmacology and Physiology (2004)
Antioxidant Mechanism

Quercetin helped limit high-glucose damage to brain blood vessel cells

In cultured cerebral endothelial cells exposed to high glucose, quercetin (among other polyphenols tested) reduced pro-inflammatory gene activation and helped preserve the tight-junction proteins that keep the blood-brain barrier intact.

Preclinical study
Taile et al., International Journal of Molecular Sciences (2021)
Capillary & Blood Vessel Research

A quercetin glucoside reversed inflammatory breakdown of a vessel barrier

In a human myocardial vessel-wall model, quercetin glucoside (50 micromolar) prevented and, within 6 to 8 hours, reversed the breakdown of the postcapillary venular barrier triggered by inflammatory mediators - directly relevant to quercetin's traditional use as a capillary/vessel protectant.

Ex vivo human tissue study
Juchem et al., American Journal of Physiology - Heart and Circulatory Physiology (2011)
Capillary & Blood Vessel Research

Quercitrin improved capillary density and blood flow recovery in an ischemic-limb model

Quercitrin (a natural quercetin glycoside) reduced oxidative damage to endothelial progenitor cells and, when injected into an ischemic mouse hind limb, improved local blood flow recovery and capillary density versus untreated controls.

Preclinical study
Zhi et al., Angiogenesis (2016)
Capillary & Blood Vessel Research

A quercetin glycoside showed no significant effect on blood vessel dilation in a trial

In a 4-week randomized, double-blind, placebo-controlled trial, quercetin-3-glucoside (160mg/day) did not significantly change flow-mediated dilation, insulin resistance, or other cardiovascular risk markers, unlike epicatechin tested in the same study.

Human RCT
Dower et al., American Journal of Clinical Nutrition (2015)
Cardiovascular Risk Markers

500mg/day quercetin capsules reduced blood pressure in women with type 2 diabetes

In a 10-week double-blind randomized trial, women with type 2 diabetes taking a 500mg quercetin capsule daily saw a significantly greater reduction in systolic blood pressure and lower TNF-alpha and IL-6 than placebo, though most other risk markers were unchanged.

Human RCT
Zahedi et al., International Journal of Preventive Medicine (2013)
Cardiovascular Risk Markers

Quercetin reduced blood pressure and oxidized LDL with no adverse safety signals

In a 6-week placebo-controlled crossover trial, 150mg/day of quercetin reduced systolic blood pressure and oxidized LDL cholesterol in overweight adults with cardiovascular risk factors, while blood tests of liver function, kidney function and hematology showed no adverse changes.

Human RCT
Egert et al., British Journal of Nutrition (2009)
Cardiovascular Risk Markers

Quercetin lowered ambulatory blood pressure specifically in hypertensive patients

In overweight-to-obese adults, a 162mg/day quercetin-rich onion skin extract lowered 24-hour ambulatory systolic blood pressure by 3.6 mmHg in the hypertensive subgroup, though it had no significant effect across the total study group.

Human RCT
Brull et al., British Journal of Nutrition (2015)
Mast Cell & Histamine Mechanism Research

Quercetin outperformed a standard mast cell stabilizer in lab testing

In cultured human mast cells, quercetin inhibited release of the inflammatory mediators IL-8 and TNF more effectively than cromolyn (the only marketed mast cell stabilizer), and in two small open-label pilot trials was associated with improvements in contact dermatitis and photosensitivity.

Preclinical + pilot trial
Weng et al., PLoS ONE (2012)
Mast Cell & Histamine Mechanism Research

Quercetin blocked a receptor pathway involved in non-allergic reactions

In mouse and cell-based models, quercetin dose-dependently reduced histamine release, calcium signaling and swelling triggered through the Mrgprx2 receptor, a pathway implicated in drug-related pseudo-allergic reactions.

Preclinical study
Ding et al., International Immunopharmacology (2018)
Mast Cell & Histamine Mechanism Research

Quercetin inhibited histamine release from human mast cells via calcium signaling

Quercetin inhibited the release of histamine, leukotrienes and prostaglandin D2 from human cultured mast cells stimulated with IgE, working in part by blocking calcium influx and protein kinase C activation.

Preclinical study
Kimata et al., Clinical and Experimental Allergy (2000)
Allergy-Related Human Research

A bioavailable quercetin supplement eased pollinosis symptoms in a 4-week trial

In a randomized, double-blind, placebo-controlled trial, adults with pollinosis taking a bioavailable quercetin phytosome supplement (200mg/day) for 4 weeks showed significant improvement in eye itching, sneezing, nasal discharge and quality-of-life scores compared with placebo.

Human RCT
Yamada et al., European Review for Medical and Pharmacological Sciences (2022)
Allergy-Related Human Research

Quercetin suppressed IgE-mediated mast cell activation in a mouse allergy model

Quercetin (alongside the related flavonoid kaempferol) inhibited secretion of histamine and inflammatory cytokines from IgE-sensitized mast cells, and suppressed passive cutaneous anaphylaxis in a mouse model of immediate-type allergic reaction.

Preclinical study
Kim et al., Journal of Agricultural and Food Chemistry (2014)
Allergy-Related Human Research

A review finds strong preclinical support but only 2 human trials of quercetin alone

A narrative review of quercetin's antiallergic activity found extensive supportive in vitro and animal evidence (including murine models of allergic rhinitis), but identified only two clinical trials testing quercetin as a standalone treatment in humans, calling for larger studies.

Review
Naso et al., Nutrients (2025)
Immune Function & Exercise Research

Quercetin reduced post-exercise illness in a cyclist trial

In trained male cyclists completing 3 days of intensive cycling, 3 weeks of quercetin (1,000mg/day) significantly reduced the incidence of upper respiratory tract infections in the 2 weeks afterward (1 of 20 vs 9 of 20 with placebo), though it did not change several direct measures of immune cell function.

Human RCT
Nieman et al., Medicine & Science in Sports & Exercise (2007)
Immune Function & Exercise Research

A review flags quercetin as worth studying for exercise-induced immune dips

A review of nutrition strategies for athletes describes quercetin, alongside beta-glucan and curcumin, as a nutritional component that animal research suggests may counter exercise-induced immune dysfunction, warranting further human investigation.

Review
Nieman & Bishop, Journal of Sports Sciences (2006)
Immune Function & Exercise Research

A systematic review found mixed results for quercetin and exercise performance

A systematic review of 51 clinical studies found quercetin supplementation improved exercise performance in about 25% of the studies reviewed - a smaller share than seen for anthocyanin-rich extracts (54%) - with limited data linking any benefit to immune-marker changes.

Systematic review
Ruiz-Iglesias et al., Nutrients (2021)
Documented Safety Considerations

A safety review flagged gaps in long-term, high-dose quercetin data

A safety review of isolated quercetin supplements found reported adverse effects are rare and mild, but noted that adequate long-term (over 12 weeks) safety data at high doses (1,000mg or more per day) are not yet available, and flagged potential kidney and drug-interaction concerns in animal studies as areas warranting caution.

Review
Andres et al., Molecular Nutrition & Food Research (2018)
Documented Safety Considerations

Regulators concluded quercetin is not classifiable as carcinogenic to humans

A review of quercetin's safety literature notes that although quercetin shows mutagenic activity in bacterial (Ames) assays, the International Agency for Research on Cancer concluded in 1999 that it is not classifiable as carcinogenic to humans, and earlier rat carcinogenicity findings were not reproduced.

Review
Okamoto, International Journal of Molecular Medicine (2005)
Documented Safety Considerations

A related quercetin glycoside's safety review set an acceptable daily intake

A safety review of isoquercitrin (a natural quercetin glycoside) established an acceptable daily intake, found higher doses in rats produced mostly benign effects, and flagged possible interactions with drug-metabolizing and transport enzymes as a consideration for supplement users.

Review
Valentova et al., Food and Chemical Toxicology (2014)

Customer Reviews

4.7 out of 5 · 225 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

What is CanPrev Quercetin 500mg and what does it do?

It's a 500mg vegetable capsule of pure quercetin, naturally sourced from the flower bud of the Japanese pagoda tree. It provides antioxidants and is used in Herbal Medicine as a capillary/blood vessel protectant, supporting healthy circulation.

How do I take it?

Adults take 1 capsule, 1 to 2 times per day with food, or as directed by a qualified health care practitioner. Ask a health care practitioner before using for more than 12 weeks.

How long does one bottle last?

Each bottle contains 120 vegetable capsules - a 120-day supply at the minimum dose of 1 capsule daily, or a 60-day supply at 2 capsules daily.

Is it vegan, and what's in the capsule shell?

Yes - it's vegan, non-GMO and gluten-free. The only non-medicinal ingredient is hypromellose, the vegetable capsule shell - there are no fillers or binders.

Does quercetin help with seasonal allergies?

This product's licensed use is as an antioxidant and capillary/blood vessel protectant. Quercetin's effects on histamine and mast cells are an active area of research (see below), but this product does not carry a specific allergy-relief claim on its Health Canada license.

Who should use caution, or not use it?

Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Keep out of reach of children. Do not use if the safety seal is broken.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

500mg Pure Quercetin · VeganCapillary & Blood Vessel Support120 V-Caps · 120-Day SupplyNon-GMO · Gluten-Free · Formulated in Canada

Support antioxidant and circulation health with quercetin

Get CanPrev Quercetin 500mg on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80101190. Provides antioxidants. Used in Herbal Medicine as a capillary/blood vessel protectant. The research summaries below concern quercetin generally and are educational - they are not claims about this finished product. Read and follow the label. Ask a health care practitioner before use for more than 12 weeks. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Keep out of reach of children. Do not use if safety seal is broken.

Indications

Recommended Use or Purpose: Provides antioxidants. Used in Herbal Medicine as a capillary/blood vessel protectant.

Ingredients

Medicinal ingredients (per capsule): Quercetin (flower bud, Styphnolobium japonicum) 500 mg. Non-medicinal ingredients: Hypromellose (vegetable capsule shell). NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults): Take 1 capsule, 1 to 2 times per day with food, or as directed by a health care practitioner. Duration of Use: For use beyond 12 weeks, consult a health care practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

$53.99 CAD4.7 ★ (225) Get it on Amazon →