CanPrev Pro-Biotik Infant Drops with Vitamin D3 | 10mL
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 serving (5 drops) per day (infants age 0+) |
| Licensed Natural Health Product | NPN 80108938 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 2 BILLION CFU + 400 IU VITAMIN D3: Each 5-drop serving provides 1 billion CFU Lacticaseibacillus rhamnosus GG, 1 billion CFU Bifidobacterium animalis subsp. lactis DSM 15954, and 400 IU vitamin D3 (cholecalciferol).
- HELPS REDUCE COLIC CRYING IN BREASTFED INFANTS: This product's Health Canada-authorized use (NPN 80108938) includes helping reduce crying episodes and relieve symptoms of colic in breastfed infants.
- SUPPORTS GUT AND IMMUNE HEALTH FROM BIRTH: Supports gastrointestinal health and immune function in infants age 0 and up.
- HELPS BUILD STRONG BONES AND TEETH: The added 400 IU of vitamin D3 helps build strong bones and teeth alongside the probiotic strains.
- EASY LIQUID DROPPER FORMAT: Give directly on the tongue, mixed into expressed breast milk or formula, or spoon-fed - shake well before use.
- DAIRY-FREE, GLUTEN-FREE, MADE IN CANADA: Formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed under NPN 80108938.
Product Description
Pro-Biotik Infant Drops - 2 Billion CFU + 400 IU Vitamin D3
CanPrev Pro-Biotik Infant Drops combine two real, dosed probiotic strains - Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis DSM 15954 - with 400 IU of vitamin D3 (cholecalciferol) in an easy liquid dropper format. Supports gastrointestinal health and immune function, helps build strong bones and teeth, and helps reduce crying episodes and relieve symptoms of colic in breastfed infants. Dairy-free, gluten-free, and licensed as a Natural Health Product for infants age 0 and up. Licensed Natural Health Product NPN 80108938.
Les Gouttes pour Nourrissons Pro-Biotik de CanPrev combinent deux souches probiotiques réelles et dosées - Lacticaseibacillus rhamnosus GG et Bifidobacterium animalis subsp. lactis DSM 15954 - avec 400 UI de vitamine D3 (cholécalciférol) dans un format liquide facile à administrer avec compte-gouttes. Aide à soutenir la santé gastro-intestinale et les fonctions immunitaires, aide à former des os et des dents solides, et aide à réduire les épisodes de pleurs et à soulager les symptômes de coliques chez les bébés allaités. Sans produits laitiers, sans gluten, et homologué comme produit de santé naturel pour les bébés âgés de 0 an et plus. NPN 80108938.
Built for Delicate Tummies
Lacticaseibacillus rhamnosus GG + Bifidobacterium animalis subsp. lactis DSM 15954 + 400 IU Vitamin D3 - 1 serving (5 drops) daily
2 Real Probiotic Strains + Vitamin D3
Each 5-drop serving provides 1 billion CFU Lacticaseibacillus rhamnosus GG, 1 billion CFU Bifidobacterium animalis subsp. lactis DSM 15954, and 400 IU vitamin D3 (cholecalciferol) - a real, dosed formula, not a proprietary blend.
An Easy Liquid Dropper Format
Formulated specifically for infants age 0 and up - give directly on the tongue, mixed into expressed breast milk or formula, or spoon-fed. Shake before use.
What's Inside Every Serving
CanPrev Pro-Biotik Infant Drops combine 2 real probiotic strains with vitamin D3 - here is what each ingredient is.
Lacticaseibacillus rhamnosus GG
One of the most widely studied probiotic strains in infants, included at a real, stated dose (not a proprietary blend) for gastrointestinal and immune support.
1 Billion CFUBifidobacterium animalis subsp. lactis DSM 15954
A Bifidobacterium strain (also known as BB-12) studied specifically in breastfed infants with colic, included alongside L. rhamnosus GG for broader gut support.
1 Billion CFU
Vitamin D3 (cholecalciferol)
The standard recommended daily amount of vitamin D3 for infants, included to help build strong bones and teeth.
10 mcg (400 IU)CanPrev Pro-Biotik Infant Drops: Supplement Facts
Each serving (5 drops) contains:
- Lacticaseibacillus rhamnosus GG1 Billion CFU
- Bifidobacterium animalis subsp. lactis DSM 159541 Billion CFU
- Vitamin D3 (cholecalciferol)10 mcg (400 IU)
Non-Medicinal Ingredients: Non-medicinal ingredients: Medium chain triglycerides, monopotassium phosphate, dipotassium phosphate, silicon dioxide, sodium chloride, sucrose.
Recommended Use or Purpose: Supports gastrointestinal health and immune function. Helps build strong bones and teeth. Helps reduce crying episodes and relieve symptoms of colic in breastfed infants.
Recommended Dose (Infants age 0 and up): Take one (1) serving (5 drops) per day, or as directed by a healthcare practitioner. Take at least 2 to 3 hours before or after antibiotics. Shake before use. No refrigeration required; may be refrigerated to help maintain freshness.
Cautions and Warnings: Consult a healthcare practitioner before use if your infant experiences fever, vomiting, bloody diarrhea, or severe abdominal pain. Discontinue use and consult a healthcare practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond 3 days. Do not use if the safety seal is broken. Keep out of reach of children. Contraindications: Do not use if your infant has an immune-compromised condition (e.g. AIDS, lymphoma) or is undergoing long-term corticosteroid treatment.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque portion (5 gouttes) contient :
- Lacticaseibacillus rhamnosus GG1 Billion CFU
- Bifidobacterium animalis subsp. lactis DSM 159541 Billion CFU
- Vitamine D3 (cholécalciférol)10 mcg (400 IU)
Ingrédients non médicinaux : Ingrédients non médicinaux : Triglycérides à chaîne moyenne, phosphate de monopotassium, phosphate de dipotassium, dioxyde de silicium, chlorure de sodium, sucrose.
Usage ou fins recommandés : Aide à soutenir la santé gastro-intestinale et les fonctions immunitaires. Aide à former des os et des dents solides. Aide à réduire les épisodes de pleurs et à soulager les symptômes de coliques chez les bébés allaités.
Dose recommandée (bébés âgés de 0 an et plus) : Prendre une (1) portion (5 gouttes) par jour, ou selon l'avis d'un praticien de soins de santé. Prendre au moins 2 à 3 heures avant ou après la prise d'antibiotiques. Agiter avant utilisation. Aucune réfrigération requise; peut être réfrigéré pour aider à préserver la fraîcheur.
Mises en garde et avertissements : Consultez un praticien de soins de santé avant l'utilisation si votre bébé souffre de fièvre, de vomissements, de diarrhée sanglante ou de douleurs abdominales intenses. Cessez l'utilisation et consultez un praticien de soins de santé si des symptômes de troubles digestifs (par ex., diarrhée) se manifestent, s'aggravent ou persistent au-delà de 3 jours. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants. Contre-indications : Ne pas utiliser ce produit si votre bébé souffre d'un déficit immunitaire (par ex., sida, lymphome) ou subit un traitement prolongé aux corticostéroïdes.
NPN 80108938
Give your baby's gut and immune health a gentle daily boost
Get CanPrev Pro-Biotik Infant Drops on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Pro-Biotik Infant Drops
2 real, dosed probiotic strains plus 400 IU vitamin D3, in an easy liquid dropper format formulated specifically for infants.
2 real probiotic strains, fully dosed
Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis DSM 15954, each at 1 billion CFU per serving - not a hidden proprietary blend.
400 IU of vitamin D3 included
Helps build strong bones and teeth alongside gut and immune support - one less supplement to give separately.
Easy liquid dropper format
Formulated for infants age 0 and up - give directly on the tongue, in expressed breast milk or formula, or by spoon.
Trusted Canadian brand
CanPrev - formulated and made in Canada, licensed under NPN 80108938.
Inside every serving
1 billion CFU Lacticaseibacillus rhamnosus GG, 1 billion CFU Bifidobacterium animalis subsp. lactis DSM 15954, and 400 IU vitamin D3 (cholecalciferol) per 5-drop serving - formulated to support gastrointestinal health, immune function, and healthy bones and teeth in infants.
How to use it
Give 1 serving (5 drops) daily
Infants age 0 and up: take one (1) serving (5 drops) per day, or as directed by a healthcare practitioner.
Time it around antibiotics
If your infant is taking antibiotics, give this product at least 2 to 3 hours before or after the antibiotic dose.
Shake before use
Shake well before each use to ensure even dosing from the dropper. No refrigeration required, though refrigerating may help maintain freshness.
Watch for digestive upset
Consult a healthcare practitioner before use if your infant has fever, vomiting, bloody diarrhea, or severe abdominal pain; discontinue if digestive upset persists beyond 3 days.
What the research says about the strains and vitamin D3 in this formula
Educational summaries of published research on the probiotic strains and vitamin D3 in this formula, prioritizing infant and pediatric studies - not claims about this finished product. CanPrev Pro-Biotik Infant Drops' own claim is the authorized use under NPN 80108938.
A randomized trial found LGG reduced crying time in colicky breastfed infants
In a randomized controlled trial of 45 colicky breastfed infants, 28 days of Lacticaseibacillus rhamnosus GG (ATCC 53103) supplementation, combined with maternal avoidance of cow's milk, reduced median daily full-force crying from 242 to 104 minutes and significantly lowered faecal calprotectin versus placebo.
Human RCTA follow-up study linked LGG's colic benefit to lower inflammatory markers
In a randomized, double-blind, placebo-controlled study of 58 infants with colic, those treated with Lacticaseibacillus rhamnosus GG showed reduced daily crying duration alongside significantly lower interleukin-6 and TNF-alpha values after 28 days, supporting a possible anti-inflammatory mechanism.
Human RCTA larger pilot study found early LGG supplementation did not prevent later colic
A secondary analysis of 184 infants given a daily dose of LGG or a control for the first 6 months of life found no significant difference in colic diagnosis between groups - an honest null finding showing this specific outcome (prevention, not treatment) was not established.
Human RCTA randomized trial found BB-12 reduced crying and improved gut markers in colicky infants
In a randomized, double-blind, placebo-controlled trial of 80 exclusively breastfed infants with colic, supplementation with Bifidobacterium animalis subsp. lactis BB-12 for 28 days produced a higher rate of infants achieving a 50% or greater reduction in daily crying time, alongside increased Bifidobacterium abundance and gut-barrier markers.
Human RCTA second RCT found BB-12 reduced crying episodes and improved caregiver quality of life
In a randomized, double-blind, placebo-controlled study of 192 infants with colic in China, 21 days of Bifidobacterium animalis subsp. lactis BB-12 significantly reduced the number of daily crying episodes, increased daily sleep duration, and improved caregiver-reported quality of life compared with placebo.
Human RCTA clinical review identifies BB-12 among the strongest-evidence strains for breastfed infant colic
A review of probiotic use for functional gastrointestinal disorders in children concludes that the strongest evidence for treating infantile colic in breastfed infants exists for Limosilactobacillus reuteri DSM 17938 and Bifidobacterium animalis subsp. lactis BB-12.
ReviewAn updated ESPGHAN-aligned review recommends specific strains for infant colic
A 2025 update on paediatric probiotic use reports that for infant colic, current recommendations include Limosilactobacillus reuteri DSM 17938 or Bifidobacterium lactis BB-12 specifically in breastfed infants, based on the European Society for Paediatric Gastroenterology, Hepatology and Nutrition's strain-specific guidance.
Clinical reviewA technical review recommends probiotics for infantile colic given their safety profile
A technical review of probiotic use in pediatric digestive disorders concludes that for infantile colic and chronic abdominal pain, where existing treatments have limited efficacy, probiotic use is recommended given their safety - even though the certainty of evidence is rated low to moderate.
Clinical reviewA pediatric probiotic review highlights Lactobacillus rhamnosus GG's role in infant colic
A descriptive review of probiotic use in pediatrics reports that Limosilactobacillus reuteri DSM 17938 and Lactobacillus rhamnosus GG were effective in managing infant colic, among other pediatric applications of this strain.
ReviewA meta-analysis found probiotics reduced daily crying time by an average of 51 minutes
A systematic review and meta-analysis of randomized trials using probiotics or synbiotics for infantile colic found an average reduction of 51 minutes of crying per day versus placebo, with the largest reduction (-74 minutes) seen in exclusively breastfed infants.
Meta-analysisA Cochrane review found daily crying time was reduced with probiotic use, though prevention of colic itself was not established
A Cochrane review of 6 randomized trials (1,886 infants) found no clear evidence that probiotics given from birth prevent new cases of colic, but a pooled analysis of 3 studies found daily crying time was reduced by an average of 32.6 minutes with probiotic use versus placebo, with no clear difference in serious adverse events.
Systematic reviewA narrative review identifies BB-12 and L. reuteri among the interventions with significant colic benefit
A narrative review of nutraceuticals for infant and pediatric gut-brain pain disorders reports that at least two double-blind randomized trials found significant reductions in colic episodes and crying time with Limosilactobacillus reuteri DSM 17938 or Bifidobacterium animalis subsp. lactis BB-12 (10^9 CFU/day for at least 21 days) in breastfed infants.
Narrative reviewA narrative review describes how feeding practices shape the infant gut microbiome and immune maturation
A narrative review of infant gut microbiota development reports that exclusive breastfeeding supports a microbial profile enriched in bifidobacteria and contributes to immune system maturation, while cesarean delivery can reduce initial microbial diversity by 30 to 50 percent.
ReviewA review describes the neonatal period as a critical window for gut-immune programming
A review of the pediatric gut microbiome describes the neonatal period as a critical window in which rapid microbial colonization shapes immune, metabolic, and neurodevelopmental processes, with microbiome-directed strategies including probiotics discussed as an emerging area of disease-prevention research.
ReviewA review identifies exclusive breastfeeding as the gold-standard reference for healthy infant microbiota
A review of early-life gut development describes the microbiota of term infants who are exclusively breastfed and have not been exposed to antibiotics as a reference standard for healthy colonization, within a critical early window that is accessible to modulating approaches such as probiotic supplementation.
ReviewA randomized trial supports the standard 400 IU/day vitamin D3 dose for breastfed infants
A prespecified secondary analysis of a randomized clinical trial in infants with low vitamin D status at birth found that a higher 1,000 IU/day dose did not provide any additional benefit to bone mineral content or density versus the standard 400 IU/day dose, supporting 400 IU/day as an appropriate standard supplementation level.
Human RCTA randomized study found direct infant 400 IU/day vitamin D3 supplementation as effective as high-dose maternal supplementation
A randomized, double-blind lactation study found that infant bone mineral content and density did not differ significantly between infants given direct 400 IU/day vitamin D3 and infants whose exclusively breastfeeding mothers received 6,400 IU/day, confirming direct 400 IU/day infant supplementation as a comparably effective approach.
Human RCTA Cochrane review found 400 IU/day vitamin D3 raises infant vitamin D levels and reduces insufficiency
A Cochrane review of 19 studies found that vitamin D supplementation given directly to breastfed infants at 400 IU/day increased 25-hydroxyvitamin D levels and reduced the incidence of vitamin D insufficiency compared with no supplementation, though evidence for bone-density outcomes specifically was rated very low certainty.
Systematic reviewA meta-analysis found vitamin D plays a role in immune function, though standard-dose effects on respiratory infection are limited
A systematic review and meta-analysis of 7 trials in over 5,700 children under 5 found that vitamin D supplementation above the standard 400 IU dose reduced the odds of influenza, cold, cough, and fever, underscoring the broader immune-modulating role of vitamin D in early childhood, though this specific meta-analysis addressed doses above the standard amount rather than the standard 400 IU dose itself.
Meta-analysisA prospective cohort study linked lower vitamin D levels to more severe RSV infection in infants
A prospective study of 125 previously healthy infants hospitalized with respiratory syncytial virus found that those who developed life-threatening disease had significantly lower serum vitamin D levels on admission than those with a better outcome, identifying vitamin D deficiency as an independent risk factor.
Observational studyA meta-analysis found maternal vitamin D supplementation alone did not reduce infant respiratory infections
A meta-analysis of 3 randomized trials (3,224 mother-infant pairs) found that maternal vitamin D supplementation during pregnancy had no significant effect on the incidence of respiratory tract infections in offspring - an honest null finding for that specific route of supplementation.
Meta-analysisA systematic review found Lacticaseibacillus rhamnosus is generally safe, with extra caution warranted in infants
A systematic review of 51 randomized controlled trials of Lacticaseibacillus rhamnosus concluded that it is generally considered safe for healthy individuals with no commonly reported serious adverse events, while noting that occasional adverse effects have been documented in special populations including infants, warranting caution in these groups.
Systematic reviewA meta-analysis of infant formula trials found comparable adverse event rates with or without probiotics
A systematic review and meta-analysis of 55 randomized trials (8,868 infants and children) found that the incidence of both minor and serious adverse events with probiotic-, prebiotic-, or synbiotic-supplemented formula was comparable to control formula, while beneficial gut flora abundance increased.
Meta-analysisA 2025 Cochrane update found no serious adverse events across 24 infant probiotic trials
A 2025 Cochrane review of 24 studies (7,077 mother-infant pairs) evaluating probiotics in infants found little to no difference in adverse effects between probiotic and control groups, with no serious adverse events reported for probiotics or synbiotics across the pooled evidence base.
Systematic reviewFrequently asked questions
What is CanPrev Pro-Biotik Infant Drops and what does it do?
It's a liquid probiotic and vitamin D3 supplement for infants, combining Lacticaseibacillus rhamnosus GG (1 billion CFU), Bifidobacterium animalis subsp. lactis DSM 15954 (1 billion CFU), and 400 IU vitamin D3 per 5-drop serving. It supports gastrointestinal health and immune function, helps build strong bones and teeth, and helps reduce crying episodes and relieve symptoms of colic in breastfed infants.
What does the '400' in the product name refer to?
It refers to 400 IU (10 mcg) of vitamin D3 (cholecalciferol) included in every 5-drop serving, alongside the 2 billion CFU (1 billion + 1 billion) of probiotics.
How do I give it to my baby?
Give one (1) serving (5 drops) per day directly on the tongue, mixed into expressed breast milk or formula, or spoon-fed. Shake well before use.
What age can my baby start taking this?
This product is formulated for infants age 0 and up.
Can I give this alongside antibiotics?
Yes, but give it at least 2 to 3 hours before or after an antibiotic dose.
Does it need to be refrigerated?
No - it does not require refrigeration. Refrigeration can help maintain freshness but is not necessary.
When should I avoid giving this product or consult a healthcare practitioner first?
Consult a healthcare practitioner before use if your infant has fever, vomiting, bloody diarrhea, or severe abdominal pain. Do not use if your infant has an immune-compromised condition (e.g. AIDS, lymphoma, or is undergoing long-term corticosteroid treatment), and discontinue use if digestive upset persists beyond 3 days.
Is it dairy-free and gluten-free?
Yes - it is free of gluten, dairy, wheat, soy, yeast, and artificial colours, flavours, or preservatives.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Give your baby's gut and immune health a gentle daily boost
Get CanPrev Pro-Biotik Infant Drops on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80108938. Supports gastrointestinal health and immune function. Helps build strong bones and teeth. Helps reduce crying episodes and relieve symptoms of colic in breastfed infants. Consult a healthcare practitioner before use if your infant has fever, vomiting, bloody diarrhea, or severe abdominal pain, or if your infant has an immune-compromised condition. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a healthcare practitioner before use if your infant experiences fever, vomiting, bloody diarrhea, or severe abdominal pain. Discontinue use and consult a healthcare practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond 3 days. Do not use if the safety seal is broken. Keep out of reach of children. Contraindications: Do not use if your infant has an immune-compromised condition (e.g. AIDS, lymphoma) or is undergoing long-term corticosteroid treatment.
Indications
Recommended Use or Purpose: Supports gastrointestinal health and immune function. Helps build strong bones and teeth. Helps reduce crying episodes and relieve symptoms of colic in breastfed infants.
Ingredients
Medicinal Ingredients (per 1 serving/5 drops): Lacticaseibacillus rhamnosus GG, 1 billion CFU. Bifidobacterium animalis subsp. lactis DSM 15954, 1 billion CFU. Vitamin D3 (cholecalciferol), 10 mcg (400 IU). Non-medicinal Ingredients: Medium chain triglycerides, monopotassium phosphate, dipotassium phosphate, silicon dioxide, sodium chloride, sucrose.
Directions
Recommended Dose (Infants age 0 and up): Take one (1) serving (5 drops) per day, or as directed by a healthcare practitioner. Take at least 2 to 3 hours before or after antibiotics. Shake before use. No refrigeration required; may be refrigerated to help maintain freshness.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.