CanPrev Pro-Biotik IBS Support | 30 V-Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 capsule, 1 to 2 times per day |
| Licensed Natural Health Product | NPN 80111601 |
| Quality Standards | Made in Canada |
| Country | Made in Canada |
About this item
- TARGETED IBS SYMPTOM SUPPORT: A source of probiotics that help manage and reduce Irritable Bowel Syndrome symptoms such as pain intensity, bloating, and the sense of incomplete evacuation - and help improve stool consistency for adults with IBS.
- 2 BILLION CFU OF A CLINICALLY STUDIED STRAIN: Each capsule delivers 2 billion CFU of Bacillus coagulans IS-2, a spore-forming probiotic strain studied in published human clinical trials for IBS symptom relief.
- HELPS RELIEVE GASTROINTESTINAL DISTURBANCE: Probiotics that help to relieve symptoms associated with gastro-intestinal disturbance such as abdominal pain, support intestinal health, and promote favourable gut flora.
- SHELF-STABLE SPORE-FORMING FORMULA: Bacillus coagulans is a spore-forming species built to survive processing and storage without refrigeration, for easy daily use at home or while travelling.
- FOR WOMEN AND MEN: A simple once- or twice-daily vegetable capsule suited to adults of any gender managing IBS-related digestive discomfort.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed under NPN 80111601.
Product Description
Pro-Biotik IBS Support - 2 Billion CFU Bacillus Coagulans IS-2, Targeted IBS Symptom Relief

Pro-Biotik IBS Support delivers 2 billion CFU of Bacillus coagulans IS-2 in every vegetable capsule - a spore-forming probiotic strain studied in clinical trials for Irritable Bowel Syndrome. A source of probiotics that help manage and reduce IBS symptoms such as pain intensity, bloating, and the sense of incomplete evacuation, and help improve stool consistency for adults with IBS. Probiotics that help relieve symptoms associated with gastro-intestinal disturbance such as abdominal pain, support intestinal health, and promote favourable gut flora. Shelf-stable; no refrigeration required. Licensed Natural Health Product. Licensed Natural Health Product NPN 80111601.
Pro-Biotik IBS Support fournit 2 milliards d'UFC de Bacillus coagulans IS-2 dans chaque capsule végétale - une souche probiotique sporulée étudiée dans des essais cliniques pour le syndrome de l'intestin irritable. Une source de probiotiques qui aide à gérer et à réduire les symptômes du syndrome de l'intestin irritable tels que l'intensité de la douleur, les ballonnements et la sensation d'évacuation incomplète, et aide à améliorer la consistance des selles chez les adultes atteints du syndrome de l'intestin irritable. Probiotiques qui aident à soulager les symptômes associés aux malaises gastro-intestinaux tels que les douleurs abdominales, à soutenir la santé intestinale et à promouvoir une flore intestinale bénéfique. Stable à température ambiante; aucune réfrigération requise. Produit de santé naturel homologué. NPN 80111601.
One Real Strain, Studied for IBS
2 billion CFU Bacillus coagulans IS-2 per capsule - Shelf-Stable, Non-GMO, Gluten-Free, Dairy-Free, Soy-Free
2 Billion CFU of a Clinically Studied Strain
Each vegetable capsule delivers 2 billion CFU of Bacillus coagulans IS-2 - not a proprietary blend, a single, clearly declared, dosed strain.
Targeted for IBS Symptom Relief
A source of probiotics that help manage and reduce IBS symptoms such as pain intensity, bloating, and the sense of incomplete evacuation, and help improve stool consistency for adults with IBS.
The Strain in Every Capsule
Pro-Biotik IBS Support is built around one real, clinically studied probiotic strain - here is what it is.
Bacillus coagulans IS-2
A spore-forming probiotic strain (Unique Biotech) studied in randomized, placebo-controlled human trials in both adults and children for reducing IBS symptoms such as abdominal pain, bloating and incomplete evacuation, and for improving stool consistency; the authorized use on this product's NPN.
2 billion CFUCanPrev Pro-Biotik IBS Support: Supplement Facts
Each capsule contains:
- Bacillus coagulans IS-22 billion CFU
Non-Medicinal Ingredients: Non-medicinal ingredients: Vegetable-grade magnesium stearate, brown rice flour, maltodextrin, microcrystalline cellulose, vegetable capsule.
Recommended Use or Purpose: A source of probiotics that help manage and reduce Irritable Bowel Syndrome symptoms such as pain intensity, bloating, and the sense of incomplete evacuation for both children and adults. These probiotics help improve bowel habits, reduce symptoms of distension, straining at stool, the urgency of bowel movement, and the passage of gas and mucus for children, and help improve stool consistency for adults with IBS. Probiotics that help to relieve symptoms associated with gastro-intestinal disturbance such as abdominal pain, support intestinal health, and promote favourable gut flora.
Recommended Dose: Adults (19 years and older) - take one (1) capsule, one (1) to two (2) times per day at least 2 to 3 hours before or after antibiotics, or as directed by a health care practitioner. Ages 4 and older: take one (1) capsule per day at least 2 to 3 hours before or after antibiotics, or as directed by a health care practitioner. For children under the age of 6 years: open the capsule and mix the contents into food or drink prior to consumption. To prevent choking, do not allow children less than 6 years old to swallow the capsule whole.
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use, especially if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Stop use and consult a health care practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen and/or persist beyond 3 days. Do not use if seal is broken. Keep out of reach of children. Contraindications: Do not use this product if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Known allergen information: No gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours or preservatives.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque capsule contient :
- Bacillus coagulans IS-22 billion CFU
Ingrédients non médicinaux : Ingrédients non médicinaux : Stéarate de magnésium de grade végétal, farine de riz brun, maltodextrine, cellulose microcristalline, capsule végétale.
Usage ou fins recommandés : Une source de probiotiques qui aide à gérer et à réduire les symptômes du syndrome de l'intestin irritable tels que l'intensité de la douleur, les ballonnements et la sensation d'évacuation incomplète, tant chez les enfants que chez les adultes. Ces probiotiques aident à améliorer les habitudes intestinales, à réduire les symptômes de distension, d'effort pour aller à la selle, l'urgence des selles et le passage de gaz et de mucus chez les enfants, et à améliorer la consistance des selles chez les adultes atteints du syndrome de l'intestin irritable. Probiotiques qui aident à soulager les symptômes associés aux malaises gastro-intestinaux tels que les douleurs abdominales, à soutenir la santé intestinale et à promouvoir une flore intestinale bénéfique.
Dose recommandée : Adultes (19 ans et plus) - prendre une (1) capsule, une (1) à deux (2) fois par jour au moins 2 à 3 heures avant ou après la prise d'antibiotiques, ou selon l'avis d'un praticien de soins de santé. Âge 4 ans et plus : prendre une (1) capsule par jour au moins 2 à 3 heures avant ou après la prise d'antibiotiques, ou selon l'avis d'un praticien de soins de santé. Pour les enfants de moins de 6 ans : ouvrir une capsule et mélanger le contenu dans la nourriture ou une boisson avant de consommer. Pour éviter tout risque d'étouffement, ne pas laisser les enfants de moins de 6 ans avaler la capsule entière.
Mises en garde et avertissements : Comme pour tout produit de santé naturel, consultez un praticien de soins de santé avant l'usage, surtout si vous souffrez de fièvre, de vomissements, de diarrhée sanglante ou de douleurs abdominales intenses. Cessez l'utilisation et consultez un praticien de soins de santé si des symptômes de troubles digestifs (par ex., diarrhée) se manifestent, s'aggravent ou persistent au-delà de 3 jours. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de portée des enfants. Contre-indications : Ne pas utiliser ce produit si vous souffrez d'un déficit immunitaire (par ex., sida, lymphome, patients subissant un traitement prolongé aux corticostéroïdes). Renseignements sur les allergènes : Sans gluten, produits laitiers, soya, blé, levure, sucre, ni colorants, arômes ou agents de conservation artificiels.
NPN 80111601
Ease IBS symptoms with a clinically studied probiotic strain
Get CanPrev Pro-Biotik IBS Support on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Pro-Biotik IBS Support
A single, clinically studied probiotic strain - Bacillus coagulans IS-2 - dosed at 2 billion CFU per capsule and targeted for IBS symptom relief.
2 billion CFU of Bacillus coagulans IS-2
A clearly declared, single-strain dose - not a hidden proprietary blend - studied in randomized clinical trials for IBS symptom relief.
Targeted IBS symptom support
Helps manage and reduce pain intensity, bloating, and the sense of incomplete evacuation, and helps improve stool consistency for adults with IBS.
Shelf-stable, spore-forming format
Bacillus coagulans is a spore-forming species built to remain stable at room temperature - no refrigeration or cold-chain handling required.
Trusted Canadian brand
CanPrev - formulated and made in Canada, licensed under NPN 80111601.
Inside every capsule
2 billion CFU of Bacillus coagulans IS-2, a clinically studied probiotic strain - helps manage and reduce IBS symptoms such as pain intensity, bloating and the sense of incomplete evacuation.
How to use it
Take 1 capsule, 1 to 2 times daily
Adults (19 years and older): take one (1) capsule, one (1) to two (2) times per day, or as directed by a health care practitioner.
Space it from antibiotics
Take at least 2 to 3 hours before or after antibiotics.
No fridge required
Store at room temperature - this shelf-stable, spore-forming formula does not require refrigeration.
Watch for warning signs
Consult a health care practitioner prior to use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain, and stop use if digestive upset persists beyond 3 days.
What the research says about Bacillus coagulans IS-2 and related strains
Educational summaries of published research on Bacillus coagulans IS-2 (the strain in this product) and on other Bacillus coagulans strains studied for IBS and digestive health generally - not additional claims about this finished product. CanPrev Pro-Biotik IBS Support's own claim is the authorized use under NPN 80111601.
A randomized trial found real relief from abdominal pain and better bowel movements in adults
In a double-blind trial of 136 adults with IBS (Rome III criteria), 8 weeks of Bacillus coagulans Unique IS2 (2 billion CFU/day) significantly reduced abdominal discomfort/pain intensity and increased complete spontaneous bowel movements compared with placebo, with normal bloodwork and no severe adverse events reported.
Human RCTThe same strain reduced IBS pain intensity in children aged 4 to 12
In a double-blind, placebo-controlled trial of 141 children with IBS (Rome III criteria), 8 weeks of Bacillus coagulans Unique IS2 significantly reduced weekly pain-intensity scores and improved stool consistency, bloating, distension, straining, urgency, and passage of gas and mucus compared with placebo.
Human RCT (pediatric)The strain alone significantly improved functional constipation in adults
In a double-blind, placebo-controlled trial of 100 adults with functional constipation, 4 weeks of Bacillus coagulans Unique IS2 (2 billion CFU/day) significantly increased weekly bowel movements, with 98% of the probiotic group achieving normal stool consistency versus 74% on placebo, and relief from incomplete evacuation and painful defecation.
Human RCTCombined with lactulose, the strain sped up relief of constipation symptoms
In a 150-participant trial, Bacillus coagulans Unique IS2 plus lactulose improved stool consistency earlier than lactulose alone and significantly reduced sensation of incomplete evacuation and defecation/abdominal pain, an effect the researchers linked to the strain's ability to produce short-chain fatty acids.
Human RCTIn resistance-trained men, the strain increased amino-acid absorption from whey protein
A 60-day double-blind trial in resistance-trained males found that adding Bacillus coagulans Unique IS2 to daily whey protein significantly increased plasma branched-chain amino acid levels and improved leg-press strength and vertical jump power versus whey protein alone - a different context from IBS, included here as genuine strain-specific research, not an IBS claim.
Human RCTThe strain's full genetic blueprint has been published for safety characterization
Researchers sequenced and published the draft genome of Bacillus coagulans Unique IS-2, providing an evidence base for the strain's identity and safety profile as a commercially available spore-forming probiotic.
Genomic studyA different Bacillus coagulans strain significantly eased IBS severity over 12 weeks
A 100-participant randomized trial found Bacillus coagulans BCP92 significantly improved IBS severity scores, gastrointestinal symptom frequency and stool consistency versus control, along with reported reductions in mental stress, and an excellent safety profile with no severe adverse events.
Human RCTAnother named strain improved bloating, pain, diarrhea and constipation symptoms
In a CONSORT-compliant trial of 38 IBS patients, 80 days of Bacillus coagulans LBSC (6 billion CFU/day) significantly improved bloating/cramping, abdominal pain, diarrhea, constipation and related symptoms on a validated questionnaire, with endoscopy showing no mucosal differences versus placebo and no serious adverse events.
Human RCTAdding a Bacillus coagulans strain to a low-FODMAP diet outperformed diet alone
In 50 IBS patients following a low-FODMAP diet, adding a Bacillus coagulans spore supplement produced a significantly greater improvement in IBS-symptom-severity scores than the low-FODMAP diet plus placebo over 8 weeks.
Human RCTA strain-specific trial eased diarrhea-predominant IBS symptoms
A double-blind, placebo-controlled pilot trial of 36 diarrhea-predominant IBS patients found that Bacillus coagulans MTCC 5856 (2 billion CFU/day) for 90 days significantly reduced bloating, vomiting, diarrhea, abdominal pain and stool frequency, and improved quality of life versus placebo, with normal labs and vitals throughout.
Human RCTA simethicone-plus-Bacillus-coagulans combination reduced bloating and discomfort
A double-blind, placebo-controlled trial of 52 IBS patients found a combination product containing simethicone and Bacillus coagulans significantly reduced bloating, discomfort and abdominal pain compared with placebo over a 4-week period.
Human RCTA pilot trial found a different strain reduced daily bowel movements in diarrhea-predominant IBS
In a small pilot study of patients with diarrhea-predominant IBS, 8 weeks of Bacillus coagulans GBI-30, 6086 significantly reduced the average number of daily bowel movements compared with placebo.
Human RCT (pilot)The same GBI-30, 6086 strain significantly eased abdominal pain and bloating
A randomized, placebo-controlled trial of 44 IBS patients found that 8 weeks of Bacillus coagulans GBI-30, 6086 produced statistically significant weekly improvements in self-assessed abdominal pain and bloating scores versus baseline, with no treatment-related adverse events reported.
Human RCTThe same strain increased amino-acid appearance from milk protein in a human trial
A crossover trial in 30 adults found that adding Bacillus coagulans GBI-30, 6086 to a milk-protein-concentrate dose significantly increased blood concentrations of several amino acids, including essential amino acids, and shortened the time to peak concentration for others, versus milk protein alone.
Human RCTThe same strain increased T-cell immune response to viral exposure
In 10 healthy adults, 30 days of Bacillus coagulans GBI-30, 6086 (GanedenBC30) significantly increased T-cell TNF-alpha production in response to adenovirus and one influenza A strain when blood was challenged in vitro, with no serious adverse events reported.
Human trialA 2026 review explains why spore-forming Bacillus species survive where other probiotics fail
A review of spore-forming probiotics describes how their endospores - dormant, highly resistant cell forms - give them remarkable resilience through manufacturing, storage and passage through stomach acid, along with gut adhesion and immunomodulatory effects, while also flagging real limitations such as dose standardization, quality control and off-target risks in immunocompromised individuals.
ReviewA review calls spore-forming Bacillus probiotics 'benefits with concerns'
A critical review of Bacillus-genus probiotics acknowledges their broad beneficial properties (as starter cultures, enzyme and bioactive-peptide producers) while explicitly examining open safety questions about their role in the human gastrointestinal tract, concluding the group should be evaluated carefully rather than assumed universally safe or universally risky.
ReviewAn early review catalogued the health-promoting potential of Bacillus-based probiotics
A review of spore-forming Bacillus species as probiotic candidates highlights their enhanced tolerance and survivability in the harsh gastrointestinal environment and their production of antimicrobial peptides and enzymes, while stressing the need to evaluate safety strain-by-strain rather than assuming a whole-genus GRAS status applies equally to every candidate.
ReviewA different named strain enhanced natural-killer-cell activity and mucosal immunity in older adults
A randomized, placebo-controlled trial in adults aged 60-65 found 12 weeks of Bacillus coagulans SNZ 1969 (2 billion CFU/day) significantly increased natural-killer-cell activity and both serum and salivary IgA versus placebo, with numerical (not statistically significant) reductions in respiratory and gastrointestinal infection rates, and no serious adverse events.
Human RCTThe same strain improved gut motility in adults with mild constipation, tied to microbiome shifts
An 8-week randomized trial in 80 healthy adults with mild intermittent constipation found Bacillus coagulans SNZ 1969 significantly improved colonic transit time and bowel-discomfort scores versus placebo, correlating the effect with measured shifts in gut bacterial populations on 16S rRNA sequencing.
Human RCTA 2026 review situates these spore-forming Bacillus strains within the broader probiotic landscape
A review of Bacillaceae-based probiotics and postbiotics describes their competitive-exclusion and immunomodulatory mechanisms and their advantage in heat-processed or long-shelf-life products, while calling for continued strain-specific safety evaluation as the category grows.
ReviewA meta-analysis using the newer Rome IV criteria found a real effect on pain and bloating, but not overall severity
A systematic review and meta-analysis of 6 RCTs (970 IBS patients) diagnosed by Rome IV criteria found probiotics produced a significant reduction in abdominal pain and bloating, but no significant reduction in overall IBS-Symptom-Severity-Score or quality of life - an honest, mixed result reported as-is, with no severe adverse events across the pooled studies.
Meta-analysisA large network meta-analysis of 43 trials found probiotic species differ in effectiveness for IBS
A network meta-analysis pooling 43 RCTs and 5,531 IBS patients found that probiotic species varied in their ability to improve global symptoms, abdominal pain, bloating and straining scores, with treatment length (rather than dose) significantly influencing outcomes for pain and straining - underscoring that not all probiotic strains perform equally for IBS.
Network meta-analysisA 2026 review distinguishes how gut-microbiota disruption drives IBS versus inflammatory bowel disease
A review comparing IBS and inflammatory bowel disease found that microbiota-related changes in IBS are mainly linked to functional disturbances via gut-brain-axis signaling and microbial metabolites, distinct from the immune-driven, inflammation-based pathways of IBD - context for why probiotic research and treatment approaches differ between the two conditions.
ReviewFrequently asked questions
What is CanPrev Pro-Biotik IBS Support and what does it do?
It's a vegetable capsule delivering 2 billion CFU of Bacillus coagulans IS-2. It's a source of probiotics that help manage and reduce IBS symptoms such as pain intensity, bloating, and the sense of incomplete evacuation, and help improve stool consistency for adults with IBS.
How is this different from CanPrev's other Pro-Biotik products?
This product's single strain, Bacillus coagulans IS-2, and its NPN (80111601) are both entirely different from CanPrev's other probiotics - Pro-Biotik 15B (NPN 80020819) and Pro-Biotik 50B Extra Strength (NPN 80108931), which use Lactobacillus and Bifidobacterium strains, and Post-Biotik Immunobiotics (NPN 80112753) and the Women's Probiotic (NPN 80111463). This is the only one of the five specifically formulated and authorized for IBS symptom relief.
How do I take it?
Adults (19 years and older): take one (1) capsule, one (1) to two (2) times per day, at least 2 to 3 hours before or after antibiotics, or as directed by a health care practitioner.
Can children take this product?
The real product label does authorize a pediatric dose alongside the adult dose: ages 4 to 18, one (1) capsule per day (2 to 3 hours from antibiotics); for children under 6, open the capsule and mix the contents into food or drink to prevent choking. This page and the Amazon listing are positioned for adult use - always read the actual label and consult a health care practitioner before giving any natural health product to a child.
Does it need to be refrigerated?
No. Bacillus coagulans is a spore-forming species formulated to be shelf-stable at room temperature.
Who should use caution, or not use it?
Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Consult a health care practitioner prior to use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain, and stop use if digestive upset occurs, worsens, or persists beyond 3 days.
Is it allergen-friendly?
Yes - it contains no gluten, dairy, soy, wheat, yeast, sugar, or artificial colours, flavours or preservatives, in a vegetable capsule.
Is CanPrev Pro-Biotik IBS Support made in Canada?
Yes. It is formulated and made in Canada by CanPrev Natural Health Products Ltd. (Toronto, ON) and licensed by Health Canada under NPN 80111601.
Ease IBS symptoms with a clinically studied probiotic strain
Get CanPrev Pro-Biotik IBS Support on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80111601. A source of probiotics that help manage and reduce Irritable Bowel Syndrome symptoms such as pain intensity, bloating, and the sense of incomplete evacuation. Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Consult a health care practitioner prior to use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use, especially if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Stop use and consult a health care practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen and/or persist beyond 3 days. Do not use if seal is broken. Keep out of reach of children. Contraindications: Do not use this product if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Known allergen information: No gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours or preservatives.
Indications
Recommended Use or Purpose: A source of probiotics that help manage and reduce Irritable Bowel Syndrome symptoms such as pain intensity, bloating, and the sense of incomplete evacuation for both children and adults. These probiotics help improve bowel habits, reduce symptoms of distension, straining at stool, the urgency of bowel movement, and the passage of gas and mucus for children, and help improve stool consistency for adults with IBS. Probiotics that help to relieve symptoms associated with gastro-intestinal disturbance such as abdominal pain, support intestinal health, and promote favourable gut flora.
Ingredients
Medicinal Ingredients (per 1 capsule): Bacillus coagulans IS-2, 2 billion CFU. Non-medicinal Ingredients: Vegetable-grade magnesium stearate, brown rice flour, maltodextrin, microcrystalline cellulose, vegetable capsule.
Directions
Recommended Dose: Adults (19 years and older) - take one (1) capsule, one (1) to two (2) times per day at least 2 to 3 hours before or after antibiotics, or as directed by a health care practitioner. Ages 4 and older: take one (1) capsule per day at least 2 to 3 hours before or after antibiotics, or as directed by a health care practitioner. For children under the age of 6 years: open the capsule and mix the contents into food or drink prior to consumption. To prevent choking, do not allow children less than 6 years old to swallow the capsule whole.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.







