CanPrev Pro-Biotik Bowel Transit | 30 V-Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 capsule per day |
| Licensed Natural Health Product | NPN 80101315 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- 1.8 BILLION CFU OF A SINGLE CLINICALLY STUDIED STRAIN: Each capsule delivers 1.8 billion CFU of Bifidobacterium animalis subsp. lactis HN-019 - a specific, dosed strain, not a hidden proprietary blend.
- TARGETED FOR BOWEL TRANSIT, NOT GENERAL DIGESTION: Formulated specifically to promote a favourable intestinal microflora, promote bowel movements, and help accelerate intestinal transit time - CanPrev's regularity-focused probiotic.
- GENTLE, ONE-A-DAY DOSING: Adults take just 1 capsule per day, at least 2 to 3 hours before or after antibiotics.
- SHELF-STABLE VEGETABLE CAPSULE: No refrigeration required - a convenient, travel-friendly one-a-day capsule in a vegetable-based shell.
- FREE OF COMMON ALLERGENS: No gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours or preservatives.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed under NPN 80101315.
Product Description
Pro-Biotik Bowel Transit - 1.8 Billion CFU Bifidobacterium animalis subsp. lactis HN-019
Pro-Biotik Bowel Transit is CanPrev's regularity-focused, one-a-day probiotic, delivering 1.8 billion CFU of a single clinically studied strain - Bifidobacterium animalis subsp. lactis HN-019. It is a source of probiotics that helps promote a favourable intestinal microflora, promotes bowel movements, and helps accelerate intestinal transit time. Shelf-stable, vegetable-capsule format, free of gluten, dairy, soy, wheat, yeast, sugar, and artificial colours, flavours or preservatives. Licensed Natural Health Product. Licensed Natural Health Product NPN 80101315.
Pro-Biotik Transit intestinal est le probiotique quotidien de CanPrev axé sur la régularité, fournissant 1,8 milliard d'UFC d'une seule souche étudiée cliniquement - Bifidobacterium animalis subsp. lactis HN-019. Il s'agit d'une source de probiotiques qui favorise une microflore intestinale favorable, favorise le transit intestinal et aide à accélérer le temps de transit intestinal. Format en capsule végétale, stable à température ambiante, sans gluten, produits laitiers, soya, blé, levure, sucre, colorants, aromatisants ou agents de conservation artificiels. Produit de santé naturel homologué. NPN 80101315.
One Strain, One Purpose: Bowel Transit
1.8 billion CFU Bifidobacterium animalis subsp. lactis HN-019 per capsule - take 1 capsule daily, at least 2-3 hours from antibiotics
1.8 Billion CFU of Bifidobacterium animalis subsp. lactis HN-019
A single, fully dosed clinically studied strain per capsule - not a proprietary multi-strain blend - formulated specifically for bowel regularity and transit time.
Gentle, One-a-Day Dosing
Adults take just 1 capsule per day, at least 2 to 3 hours before or after antibiotics, or as directed by a healthcare practitioner.
Why This Formula
Pro-Biotik Bowel Transit is built around one real, dosed active - Bifidobacterium animalis subsp. lactis HN-019 - rather than a crowded multi-strain blend.
Bowel Movement & Regularity Support
Source of probiotics that helps promote a favourable intestinal microflora and promotes bowel movements - this product's Health Canada-authorized use.
1.8 Billion CFU HN-019 per Capsule
A single, clinically studied Bifidobacterium strain, fully dosed at 1.8 billion CFU per capsule.
Helps Accelerate Intestinal Transit Time
Formulated to help speed up intestinal transit time as part of this product's authorized use.
Shelf-Stable, Allergen-Free Capsule
No refrigeration required; free of gluten, dairy, soy, wheat, yeast, sugar, and artificial colours, flavours or preservatives.
CanPrev Pro-Biotik Bowel Transit: Supplement Facts
Each capsule contains:
- Bifidobacterium animalis subsp. lactis HN-0191.8 billion CFU
Non-Medicinal Ingredients: Non-medicinal ingredients: Acacia (Fibregum), ascorbic acid, dipotassium phosphate, hypromellose, magnesium stearate, microcrystalline cellulose, monopotassium phosphate, sugars (sucrose).
Recommended Use or Purpose: Source of probiotics that helps promote a favourable intestinal microflora. Promotes bowel movements. Helps accelerate intestinal transit time.
Recommended Dose (Adults 19 years and older): Take 1 capsule per day, at least 2 to 3 hours before or after antibiotics, or as directed by a healthcare practitioner.
Cautions and Warnings: As with any natural health product, consult a healthcare practitioner before use of this product if you have a fever, vomiting, bloody diarrhea, or severe abdominal pain. Discontinue use and consult a healthcare practitioner if symptoms of digestive upset, such as diarrhea, occur, worsen, or persist beyond 3 days. Do not use if the safety seal is broken. Keep out of reach of children. Contraindications: Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, or if you are undergoing long-term corticosteroid treatment).
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque capsule contient :
- Bifidobacterium animalis subsp. lactis HN-0191.8 billion CFU
Ingrédients non médicinaux : Ingrédients non médicinaux : Acacia (Fibregum), acide ascorbique, phosphate de dipotassium, hypromellose, stéarate de magnésium, cellulose microcristalline, phosphate monopotassique, sucres (sucrose).
Usage ou fins recommandés : Source de probiotiques qui aide à favoriser une microflore intestinale favorable. Favorise le transit intestinal. Aide à accélérer le temps de transit intestinal.
Dose recommandée (adultes de 19 ans et plus) : Prendre 1 capsule par jour, au moins 2 à 3 heures avant ou après la prise d'antibiotiques, ou selon l'avis d'un praticien de soins de santé.
Mises en garde et avertissements : Comme avec tout produit de santé naturel, consultez un praticien de soins de santé avant l'utilisation de ce produit si vous avez de la fièvre, des vomissements, de la diarrhée sanglante ou de graves douleurs abdominales. Cessez l'utilisation et consultez un praticien de soins de santé si des symptômes de troubles digestifs, comme la diarrhée, surviennent, s'aggravent ou persistent au-delà de 3 jours. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants. Contre-indications : Ne pas utiliser si vous souffrez d'un déficit immunitaire (par exemple le sida, un lymphome), ou si vous suivez un traitement prolongé aux corticostéroïdes.
NPN 80101315
Support regular bowel movements with a single clinically studied strain
Get CanPrev Pro-Biotik Bowel Transit on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Pro-Biotik Bowel Transit
A single, fully dosed 1.8 billion CFU strain - Bifidobacterium animalis subsp. lactis HN-019 - built specifically for bowel regularity and transit time.
One real, dosed strain
1.8 billion CFU of Bifidobacterium animalis subsp. lactis HN-019 - not a proprietary multi-strain blend that hides individual amounts.
Built for bowel transit, specifically
Promotes a favourable intestinal microflora, promotes bowel movements, and helps accelerate intestinal transit time - a targeted, regularity-focused use.
Gentle, one-a-day dosing
Just 1 capsule per day, at least 2-3 hours before or after antibiotics - simple to fit into a daily routine.
Trusted Canadian brand
CanPrev - formulated and made in Canada, licensed under NPN 80101315.
Inside every capsule
1.8 billion CFU of Bifidobacterium animalis subsp. lactis HN-019, a clinically studied strain formulated to promote a favourable intestinal microflora, promote bowel movements, and help accelerate intestinal transit time.
How to use it
Take 1 capsule daily
Adults (19 years and older) take 1 capsule per day, or as directed by a healthcare practitioner.
Time it around antibiotics
If taking antibiotics, take this product at least 2 to 3 hours before or after your antibiotic dose.
No refrigeration needed
Shelf-stable - store at room temperature.
Watch for warning signs
Consult a health care practitioner before use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain; discontinue and consult a practitioner if digestive upset persists beyond 3 days.
What the research says about Bifidobacterium animalis subsp. lactis HN-019
Educational summaries of published research on the Bifidobacterium animalis subsp. lactis HN-019 strain and on probiotics generally - not additional product-specific claims beyond this product's own Health Canada-authorized use. CanPrev Pro-Biotik Bowel Transit's own label claim under NPN 80101315: source of probiotics that helps promote a favourable intestinal microflora, promotes bowel movements, and helps accelerate intestinal transit time.
A 2021 review maps how HN019 may support gut motility and bowel regularity
This review of preclinical and clinical studies on Bifidobacterium animalis subsp. lactis HN019 concludes it reduced intestinal transit time and increased bowel movement frequency in functional constipation, while also helping maintain intestinal barrier function during gastrointestinal infections and supporting normal physiological function in immunosenescent elderly subjects.
ReviewA 2013 meta-analysis of 11 trials found HN019 among the strongest-performing probiotic strains for transit time
Pooling 13 treatment effects across 464 subjects, probiotic supplementation was associated with decreased intestinal transit time overall, with medium-to-large treatment effects identified specifically for Bifidobacterium lactis HN019 (SMD 0.72) and B. lactis DN-173 010 (SMD 0.54), while other single strains and combination products yielded smaller effects.
Meta-analysisA 2016 updated meta-analysis of 15 trials confirmed HN019's outsized effect on transit time
Analyzing 17 treatment effects across 675 subjects, this updated meta-analysis again found medium-to-large reductions in intestinal transit time specifically with B. lactis HN019 (SMD 0.67) and B. lactis DN-173 010 (SMD 0.54), while other probiotic strains showed only negligible reductions - effects were greatest in constipated and older subjects.
Meta-analysisA 228-person, 28-day dose-ranging RCT found a bowel-frequency benefit only in a post-hoc, low-frequency subgroup
In adults with functional constipation, there were no statistically significant differences between HN019 and placebo in the primary outcome (colonic transit time) or most secondary outcomes. In a post-hoc analysis of participants with 3 or fewer weekly bowel movements at baseline, however, both the high- and low-dose HN019 groups showed a physiologically relevant increase in bowel movement frequency versus placebo.
Human RCTA 2025 multi-center RCT found 8 weeks of HN019 was not superior to placebo for bowel movements in functional constipation
This triple-blind, randomized, placebo-controlled trial across 4 French clinical units found HN019 supplementation did not outperform placebo for complete spontaneous bowel movements, stool consistency, straining, bloating or quality-of-life scores over 8 weeks in adults with functional constipation - an honest null result from the most recent, and largest, HN019 constipation trial to date. No safety concerns were identified.
Human RCTA 2014 RCT found yogurt containing HN019 shortened colonic transit time versus yogurt alone
Constipated adults who ate yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019 daily for 14 days had a significantly shorter colonic transit time than those eating unsupplemented yogurt, alongside a favourable clinical symptom-score response in both groups.
Human RCTA tissue-bath study found HN019 extract changes colon muscle contraction patterns
In isolated rat large intestine, an extract of HN019 increased the amplitude of propagating colonic contractions in the distal colon while reducing non-propagating contractions in the proximal colon - a motility pattern the researchers describe as demonstrating prokinetic activity consistent with HN019's reduction of constipation in human studies.
Laboratory studyResearchers propose HN019 acts partly through the gut-brain-microbiota axis
The same review on HN019 and gut health proposes that its effect on constipation is potentially mediated by modulation of the gut-brain-microbiota axis, mainly via serotonin signaling driven by short-chain fatty acids produced through microbial fermentation.
ReviewA 2023 RCT found a HN019-containing combination modestly reduced plasma serotonin alongside improved stool consistency
In a 4-week, double-blinded, placebo-controlled trial of 250 adults with functional constipation, a formula combining Bifidobacterium lactis HN019 and HN001 showed a marginal reduction in plasma serotonin and a significant improvement in Bristol stool scale score versus baseline, though overall bowel movement frequency did not differ significantly between groups.
Human RCTA 2017 meta-analysis of 4 trials found HN019 boosted immune cell activity in the elderly
Pooling controlled trials in healthy elderly subjects, daily HN019 supplementation was highly efficacious in increasing polymorphonuclear phagocytic capacity (SMD 0.74) and moderately efficacious in increasing natural killer cell tumoricidal activity (SMD 0.43).
Meta-analysisA 9-week trial found HN019 enhanced multiple markers of cellular immunity in elderly volunteers
In 30 healthy elderly subjects (ages 63-84), consuming milk supplemented with HN019 increased the proportions of total, helper and activated T lymphocytes and natural killer cells in blood, along with the phagocytic and tumor-killing activity of white blood cells - with the greatest improvements seen in those with the poorest immune responses before starting.
Human RCTA 6-week trial found HN019 enhanced interferon production and phagocytic capacity in elderly subjects
Elderly volunteers who consumed milk supplemented with HN019 for 6 weeks produced significantly higher levels of interferon-alpha and showed significantly increased white blood cell phagocytic capacity compared with a milk-only control group.
Human RCTHN019 increased natural killer cell activity, with larger gains in subjects over 70
In 27 elderly volunteers, 3 weeks of dietary supplementation with HN019 (or a companion Lactobacillus rhamnosus strain) increased natural killer cell tumoricidal activity by an average of 62%, with subjects over age 70 experiencing significantly greater improvements than younger subjects.
Controlled trialA Taiwanese trial defined the cellular basis of HN019's immune effect and found it could be optimized
In 50 healthy adults (ages 41-81), HN019 enhanced phagocytic and natural killer cell activity of two distinct white blood cell types, with the degree of enhancement further increased when HN019 was delivered in an oligosaccharide-enriched milk base rather than plain milk.
Human RCTA 2025 pediatric trial of a HN019-containing blend shortened fever duration with no added digestive side effects
In 128 young children with upper respiratory infections, a probiotic mixture containing Bifidobacterium lactis HN019 (with Bifidobacterium breve M-16V and Lactobacillus rhamnosus HN001) shortened fever duration by a median of 2 days versus placebo, with no significant difference in constipation or abdominal pain between groups - real-world tolerability data in a young population.
Human RCTA 2017 meta-analysis of 21 studies found probiotics increased stool frequency and cut transit time in constipated adults
Across 2,656 subjects, probiotic-containing products (all using Lactobacillus or Bifidobacterium species) increased weekly stool frequency by a mean of 0.83 movements and reduced intestinal transit time (SMD 0.65), with larger effects in studies using stricter Rome-criteria constipation diagnoses.
Meta-analysisA 2019 RCT of a 5-strain blend including HN019 missed its primary bloating endpoint but reduced flatulence
In 156 adults with self-reported bloating and functional constipation, a 2-week probiotic blend (including HN019 alongside Lactobacillus acidophilus NCFM, L. paracasei Lpc-37, and two other B. lactis strains) did not significantly outperform placebo for its primary bloating endpoint, but a post-hoc analysis found a statistically significant reduction in flatulence at both day 7 and day 14.
Human RCTA 2025 meta-analysis found fiber-based oligosaccharides also increase stool frequency in constipated adults
Across 20 trials and 1,786 participants, non-digestible oligosaccharide supplementation (a different, fiber-based approach to regularity) significantly increased stool frequency, with a substantially larger effect in constipated individuals than in non-constipated people - complementary general research on approaches to bowel regularity.
Meta-analysisA 7-month nursing-home trial found fermented Bifidobacterium drinks normalized bowel movements
In 209 elderly nursing-home residents, daily fermented oat drinks containing Bifidobacterium longum or Bifidobacterium lactis Bb12 significantly increased the proportion of days with normal bowel function compared with a placebo drink, over 7 months.
Human RCTA 12-week RCT found a Bifidobacterium animalis-containing formula was effective and safe in elderly constipation
In 60 nursing-home residents (average age 78) with functional constipation, a multistrain probiotic including Bifidobacterium animalis subsp. lactis significantly increased cumulative stool frequency after day 71 of treatment, and was found safe and well tolerated with no significant adverse changes across 27 blood parameters tested.
Human RCTA double-coated multi-species probiotic improved straining and defecation frequency in elderly residents
In elderly nursing-home residents with functional constipation, a protective double-coating that increased bacterial survival through digestion led to significant improvements in straining effort, sensation of incomplete evacuation, and defecation frequency after 2 weeks, versus an uncoated version of the same strains.
Human RCTThe same 2025 multi-center RCT found no safety concerns with HN019, even though it did not beat placebo on efficacy
Although HN019 was not superior to placebo for bowel-movement outcomes in this trial, fecal moisture content, gut microbiota composition, and fecal calprotectin (a marker of intestinal inflammation) showed no significant differences between the HN019 and placebo groups, and no safety concerns related to supplementation were identified.
Human RCTThe same 28-day dose-ranging trial found HN019 well tolerated at both doses tested
Across the full 228-person, 28-day trial, only 3 adverse events considered unlikely related to treatment were reported in total - 2 in the low-dose HN019 group and 1 in the placebo group - with all participants followed until full recovery.
Human RCTA 2020 review found probiotics among the few constipation interventions with real evidence in long-term care, but called for more robust trials
A systematic review of non-pharmacological constipation interventions for older adults in long-term care facilities found probiotics among 5 interventions (out of 7 studies, 657 patients) that improved bowel movement frequency - but after appraising methodological quality, the reviewers could not yet strongly recommend any single non-drug intervention without more robust studies.
Systematic reviewFrequently asked questions
What is CanPrev Pro-Biotik Bowel Transit and what does it do?
It's a one-a-day capsule containing 1.8 billion CFU of a single clinically studied strain, Bifidobacterium animalis subsp. lactis HN-019. It's a source of probiotics that helps promote a favourable intestinal microflora, promotes bowel movements, and helps accelerate intestinal transit time.
How is this different from CanPrev's other Pro-Biotik products?
This product contains only one strain, Bifidobacterium animalis subsp. lactis HN-019 (NPN 80101315), specifically positioned for bowel regularity and transit time. CanPrev's other Pro-Biotik products (15 Billion CFU, 50B Extra Strength, Post-Biotik Immunobiotics) are separately licensed formulas with different strains, doses and NPNs.
How do I take it?
Adults (19 years and older) take 1 capsule per day, at least 2 to 3 hours before or after antibiotics, or as directed by a healthcare practitioner.
Does it need to be refrigerated?
No - it is shelf-stable and can be stored at room temperature.
How long does one bottle last?
Each bottle contains 30 vegetable capsules - a 30-day supply at 1 capsule per day.
Is it free of common allergens?
Yes - it contains no gluten, dairy, soy, wheat, yeast, sugar, or artificial colours, flavours or preservatives.
Who should use caution, or not use it?
Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, or if you are undergoing long-term corticosteroid treatment). Consult a health care practitioner before use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain, and discontinue use and consult a practitioner if digestive upset persists beyond 3 days.
Is CanPrev Pro-Biotik Bowel Transit made in Canada?
Yes. It is formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed by Health Canada under NPN 80101315.
Support regular bowel movements with a single clinically studied strain
Get CanPrev Pro-Biotik Bowel Transit on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80101315. Source of probiotics that helps promote a favourable intestinal microflora, promotes bowel movements, and helps accelerate intestinal transit time. Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Consult a health care practitioner prior to use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a healthcare practitioner before use of this product if you have a fever, vomiting, bloody diarrhea, or severe abdominal pain. Discontinue use and consult a healthcare practitioner if symptoms of digestive upset, such as diarrhea, occur, worsen, or persist beyond 3 days. Do not use if the safety seal is broken. Keep out of reach of children. Contraindications: Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, or if you are undergoing long-term corticosteroid treatment).
Indications
Recommended Use or Purpose: Source of probiotics that helps promote a favourable intestinal microflora. Promotes bowel movements. Helps accelerate intestinal transit time.
Ingredients
Medicinal Ingredient (per capsule): Bifidobacterium animalis subsp. lactis HN-019, 1.8 billion CFU. Non-medicinal Ingredients: Acacia (Fibregum), ascorbic acid, dipotassium phosphate, hypromellose, magnesium stearate, microcrystalline cellulose, monopotassium phosphate, sugars (sucrose). NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults 19 years and older): Take 1 capsule per day, at least 2 to 3 hours before or after antibiotics, or as directed by a healthcare practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.