CanPrev Pro-Biotik 15 Billion CFU - 5 Strains | 60 V-Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 or 2 capsules per day |
| Licensed Natural Health Product | NPN 80020819 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- 5-STRAIN MULTI-SPECIES PROBIOTIC: Each capsule contains Bifidobacterium bifidum HA-132, Bifidobacterium longum HA-135, Lactobacillus acidophilus HA-122, Lactobacillus plantarum HA-119 and Lactobacillus rhamnosus HA-111 - a real, dosed 5-strain formula, not a proprietary blend.
- 15 BILLION CFU GUARANTEED AT EXPIRY: Manufactured to a minimum of 40 billion CFU to offset gradual potency loss during shelf storage, so the label's 15 billion CFU is still guaranteed on the actual expiry date - not just on the day it was made.
- SOURCE OF PROBIOTICS FOR GUT FLORA: A source of probiotics that promotes a favourable gut flora and helps support gastrointestinal health.
- SHELF-STABLE, NO REFRIGERATION NEEDED: Completely shelf-stable for use anytime, anywhere - no cold-chain storage required, making it travel-friendly.
- VEGETARIAN, NON-GMO, GLUTEN-FREE: Encapsulated in a vegetable capsule with no gluten, wheat or artificial colours - suitable for both men and women.
- MADE IN CANADA: Formulated and made in Canada by CanPrev, licensed under Health Canada NPN 80020819.
Product Description
Pro-Biotik 15B - 5 Real Probiotic Strains, 15 Billion CFU Guaranteed at Expiry
Each capsule delivers a real, dosed combination of 5 probiotic strains - Bifidobacterium bifidum HA-132, Bifidobacterium longum HA-135, Lactobacillus acidophilus HA-122, Lactobacillus plantarum HA-119 and Lactobacillus rhamnosus HA-111 - manufactured to a minimum of 40 billion CFU so that a guaranteed 15 billion CFU remains active through the labelled expiry date. A source of probiotics that promotes a favourable gut flora and helps support gastrointestinal health. Completely shelf-stable; no refrigeration required. Licensed Natural Health Product. Licensed Natural Health Product NPN 80020819.
Chaque capsule fournit une combinaison réelle et dosée de 5 souches probiotiques - Bifidobacterium bifidum HA-132, Bifidobacterium longum HA-135, Lactobacillus acidophilus HA-122, Lactobacillus plantarum HA-119 et Lactobacillus rhamnosus HA-111 - fabriquée à un minimum de 40 milliards d'UFC afin qu'un minimum garanti de 15 milliards d'UFC demeure actif jusqu'à la date de péremption indiquée. Est une source de probiotiques qui favorise une flore intestinale bénéfique et aide à soutenir la santé gastro-intestinale. Entièrement stable à température ambiante; aucune réfrigération requise. Produit de santé naturel homologué. NPN 80020819.
5 Real Strains, One Daily Capsule
Bifidobacterium bifidum + B. longum + Lactobacillus acidophilus + L. plantarum + L. rhamnosus - Shelf-Stable, Non-GMO, Gluten-Free, Vegetarian
15 Billion CFU Guaranteed at Expiry
Manufactured to a minimum of 40 billion CFU at the time of manufacture so that a guaranteed 15 billion CFU remains active on the labelled expiry date - not just on the day it was made.
5 Therapeutic Species, Fully Dosed
A real, dosed combination of 5 probiotic strains from the Lactobacillus and Bifidobacterium families - not a proprietary blend that hides individual strain amounts.
The 5 Strains in Every Capsule
CanPrev Pro-Biotik 15B combines 5 real probiotic strains - here is what each one is.
Bifidobacterium bifidum HA-132
One of two Bifidobacterium species in this formula, naturally found in the large intestine and studied for its role in gut microbial balance.
2.25 Billion CFUBifidobacterium longum HA-135
A large-intestine-associated Bifidobacterium strain included alongside B. bifidum for broader colonization support.
2.25 Billion CFULactobacillus acidophilus HA-122
A well-studied Lactobacillus species that colonizes the small intestine and is commonly included in digestive-health probiotic formulas.
1.50 Billion CFU
Lactobacillus plantarum HA-119
The highest-dosed strain in this formula, a Lactobacillus species studied for its effects on abdominal comfort and bloating.
4.95 Billion CFULactobacillus rhamnosus HA-111
A widely studied Lactobacillus species included for its role in supporting gut and immune health.
4.05 Billion CFUCanPrev Pro-Biotik 15 Billion CFU: Supplement Facts
Product Facts
- Lactobacillus plantarum HA-1194.95 Billion CFU
- Lactobacillus rhamnosus HA-1114.05 Billion CFU
- Bifidobacterium bifidum HA-1322.25 Billion CFU
- Bifidobacterium longum HA-1352.25 Billion CFU
- Lactobacillus acidophilus HA-1221.50 Billion CFU
Non-Medicinal Ingredients: Total: minimum 40 billion CFU at time of manufacture and 15 billion CFU at expiry. Non-medicinal ingredients: Ascorbic acid, fatty acids, silicon dioxide, potato starch, vegetable capsule.
Recommended Use or Purpose: Pro-Biotik 15B is a source of probiotics that promotes a favourable gut flora and helps support gastrointestinal health.
Recommended Dose (Adults): Take one (1) or two (2) capsules per day with food, or as directed by a health care practitioner.
Cautions and Warnings: As with any natural health product, you should consult a health care practitioner on the use of this product. Consult a health care practitioner prior to use if you have fever, vomiting, bloody diarrhea or severe abdominal pain. Discontinue use and consult a health care practitioner if symptoms of digestive upset, such as diarrhea, occur, worsen or persist beyond 3 days. Do not use if seal is broken. Keep out of reach of children. Contraindications: Do not use if you have an immune-compromised condition such as AIDS or lymphoma, or if you are undergoing long-term corticosteroid treatment. Known Adverse Reactions: This product has come into contact with milk and soy. Do not use if you are allergic to dairy or soy products.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Info-produit
- Lactobacillus plantarum HA-1194.95 Billion CFU
- Lactobacillus rhamnosus HA-1114.05 Billion CFU
- Bifidobacterium bifidum HA-1322.25 Billion CFU
- Bifidobacterium longum HA-1352.25 Billion CFU
- Lactobacillus acidophilus HA-1221.50 Billion CFU
Ingrédients non médicinaux : Total : minimum de 40 milliards d'UFC au moment de la fabrication et 15 milliards d'UFC à la date d'expiration. Ingrédients non médicinaux : Acide ascorbique, acides gras, dioxyde de silicium, amidon de pomme de terre, capsule végétale.
Usage ou fins recommandés : Pro-Biotik 15B est une source de probiotiques qui favorise une flore intestinale bénéfique et aide à soutenir la santé gastro-intestinale.
Dose recommandée (adultes) : Prendre une (1) ou deux (2) capsules par jour avec de la nourriture, ou selon l'avis d'un praticien de soins de santé.
Mises en garde et avertissements : Comme pour tout produit de santé naturel, vous devriez consulter un praticien de soins de santé concernant l'utilisation de ce produit. Consultez un praticien de soins de santé avant d'en faire l'usage si vous souffrez de fièvre, de vomissements, de diarrhée sanglante ou de graves douleurs abdominales. Cesser l'utilisation et consulter un praticien de soins de santé si des symptômes de troubles digestifs tels que diarrhée apparaissent, s'aggravent ou persistent au-delà de 3 jours. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de portée des enfants. Contre-indications : Ne pas utiliser ce produit si vous souffrez d'un déficit immunitaire tel que sida ou lymphome, ou si vous subissez un traitement prolongé aux corticostéroïdes. Réactions indésirables connues : Ce produit est entré en contact avec le lait et le soya. Ne pas utiliser en cas d'allergie aux produits laitiers ou au soya.
NPN 80020819
Support balanced gut flora with a shelf-stable, 5-strain probiotic
Get CanPrev Pro-Biotik 15B on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Pro-Biotik 15B
A real, dosed 5-strain probiotic - not a proprietary blend - manufactured to guarantee 15 billion CFU through the expiry date.
5 real, dosed strains
Bifidobacterium bifidum, B. longum, Lactobacillus acidophilus, L. plantarum and L. rhamnosus, each with its own stated CFU count - not a hidden proprietary blend.
15 billion CFU guaranteed at expiry
Manufactured to 40 billion CFU so a guaranteed 15 billion CFU is still active on the labelled expiry date, based on quantified stability data.
Shelf-stable, no refrigeration needed
Completely shelf-stable for ease of use anytime, anywhere - ideal for travel or everyday use.
Premium Canadian brand
CanPrev, formulated and made in Canada. NPN 80020819.
Inside every capsule
15 billion CFU (guaranteed at expiry) from 5 real probiotic strains - Bifidobacterium bifidum HA-132, Bifidobacterium longum HA-135, Lactobacillus acidophilus HA-122, Lactobacillus plantarum HA-119 and Lactobacillus rhamnosus HA-111 - formulated to support balanced intestinal flora and gastrointestinal health.
How to use it
Take 1 or 2 capsules daily
Adults take 1 or 2 capsules per day with food, or as directed by a health care practitioner.
No refrigeration needed
Store at room temperature - this shelf-stable formula does not require refrigeration, though it may be refrigerated to marginally slow potency loss if you prefer.
Watch for digestive upset
Consult a health care practitioner before use if you have fever, vomiting, bloody diarrhea or severe abdominal pain; stop use if digestive upset persists beyond 3 days.
Know the contraindications
Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, long-term corticosteroid treatment) or an allergy to dairy or soy products.
What the research says about probiotics and the strains in this formula
Educational summaries of published research on probiotics generally and on the species in this formula - not claims about this finished product. CanPrev Pro-Biotik 15B's claim is the authorized use under NPN 80020819.
The internationally recognized definition of a probiotic
An ISAPP expert consensus panel reaffirmed the FAO/WHO definition of a probiotic as 'live microorganisms which, when administered in adequate amounts, confer a health benefit on the host,' clarifying appropriate use of the term for clinicians and consumers.
Consensus statementProbiotics reinforce the gut lining and calm inflammation
A narrative review of probiotic mechanisms describes how strains such as Lactobacillus rhamnosus GG reinforce intestinal epithelial integrity via tight-junction proteins and attenuate inflammation through cytokine modulation, helping restore microbial balance in conditions like occasional digestive upset.
ReviewCombining these species safely reshapes gut microbiota
A controlled study in mice found that a compound probiotic combining Lactobacillus acidophilus, Lactobacillus rhamnosus and Bifidobacterium safely modulated gut microbial community structure and beneficial fecal metabolites, supporting the rationale for combining multiple species in one formula.
Preclinical studyHelped prevent antibiotic-associated diarrhea in a human trial
A randomized, placebo-controlled trial found that Lactobacillus acidophilus LA85 supplementation reduced the incidence of antibiotic-associated diarrhea compared with placebo in adults taking antibiotics.
Human RCTPart of a 4-strain formula that eased marathon runners' GI symptoms
In a randomized trial, recreational marathon runners taking a probiotic capsule containing Lactobacillus acidophilus and Bifidobacterium strains reported lower gastrointestinal symptom severity during training and racing than those on placebo.
Human RCTLinked to healthier cholesterol levels in meta-analyses
A narrative review reports that meta-analyses of 30+ randomized trials found probiotic supplementation with species including Lactobacillus acidophilus, L. plantarum and Bifidobacterium longum modestly lowered total and LDL cholesterol, via mechanisms including bile-salt hydrolase activity.
ReviewA randomized trial on pathogen defence in the airways
A randomised, double-blind, placebo-controlled trial found that daily Lactobacillus rhamnosus GG DSM 33156 supplementation was studied for its effects on pathogen defence in the upper respiratory tract in healthy adults.
Human RCTA large multicenter trial in children with gastroenteritis
In a multicenter randomized trial of over 1,500 children with acute gastroenteritis, a Lactobacillus rhamnosus/Lactobacillus helveticus combination did not reduce overall disease severity compared with placebo, though children with adenovirus infection who received it had fewer diarrheal episodes - an example of research reporting honest, pathogen-specific findings rather than a blanket effect.
Human RCTA large Cochrane review found no serious safety concerns
A Cochrane systematic review of 82 trials and over 12,000 participants, including studies of Lactobacillus rhamnosus GG, found no serious adverse events attributed to probiotic use in acute infectious diarrhea, even though evidence for shortening diarrhea duration was inconsistent.
Systematic reviewA 4-week trial found less pain and bloating
In a double-blind, placebo-controlled trial of 214 IBS patients, 4 weeks of Lactobacillus plantarum 299v (DSM 9843) significantly reduced abdominal pain severity and frequency compared with placebo, with similar improvements seen for bloating.
Human RCTA strain-specific review found real symptom benefits
A 2026 systematic review with meta-analysis assessing 10 individual probiotic strains for IBS found that Lactobacillus plantarum 299v (DSM 9843) was among the strains demonstrating efficacy for improving key IBS symptoms.
Systematic reviewA large meta-analysis found the certainty of evidence is still developing
An updated meta-analysis of 82 trials in over 10,000 IBS patients found low-certainty evidence for a benefit of Lactobacillus plantarum 299V on global symptoms - real but modest evidence, honestly characterized as still developing rather than definitive.
Meta-analysisNormalized bowel movements in a nursing-home trial
A randomized trial found that fermented cereal containing specific bifidobacteria normalized bowel movement frequency in elderly nursing-home residents compared with a control product.
Human RCTReduced gut-permeability and inflammation markers
A randomized, double-blind, placebo-controlled trial in adults with excess adiposity found that 8 weeks of Bifidobacterium bifidum BGN4 supplementation significantly reduced circulating zonulin (a marker of intestinal permeability), TNF-alpha and fasting insulin versus placebo, with no adverse effects observed.
Human RCTImproved stool consistency in adults prone to constipation
A randomized, double-blind, placebo-controlled trial found that a Bifidobacterium longum strain improved stool condition and overall constipation-symptom scores in healthy adults with a tendency toward constipation, compared with placebo.
Human RCTA 4-strain Lactobacillus/Bifidobacterium blend sped up bowel-habit normalization
A randomized, placebo-controlled trial of a probiotic containing Lactobacillus acidophilus DDS-1, Bifidobacterium animalis, B. longum and B. bifidum found that participants with functional constipation achieved normalized stool frequency and consistency faster than the placebo group, with all four strains significantly more abundant post-intervention.
Human RCTMeta-analysis: multistrain probiotics reduced IBS symptom severity, including bloating
A systematic review and meta-analysis of 12 studies in over 1,300 IBS patients found multistrain probiotics significantly reduced total IBS symptom-severity scores, including a significant reduction in the bloating subscore specifically.
Meta-analysisReduced gut permeability and inflammation in a combined-strain trial
A randomized, double-blind, placebo-controlled trial found that 8 weeks of a multi-strain probiotic supplement significantly reduced serum zonulin (gut permeability), oxidative stress markers and C-reactive protein compared with placebo.
Human RCTAdverse-event rates were not higher with probiotics
In the same large meta-analysis of 82 IBS trials, the relative risk of experiencing any adverse event across more than 7,000 patients was not significantly higher with probiotics than with placebo.
Meta-analysisA real-world study of over 1,000 patients found less pain and bloating
In a multicenter, real-world study of 1,098 IBS patients across Italy, 8 weeks of a probiotic mixture achieved treatment success for abdominal pain in 73% and for bloating in 82% of patients, with benefits sustained at 1-month follow-up.
Real-world studyAn umbrella review found modest but real symptom improvements
An umbrella review of 27 systematic reviews covering thousands of IBS patients found probiotics were associated with modest but statistically significant improvements in symptom persistence, with a number-needed-to-treat of 4 to 7.
Umbrella reviewImmunocompromised caution is grounded in real clinical guidance
A clinical review of probiotic use in gastrointestinal disorders notes that while probiotics are generally well-tolerated, caution has to be exercised in immunocompromised and critically ill individuals - consistent with this type of product's own labelled contraindication.
ReviewA large Cochrane review found no serious adverse events
The same Cochrane review of 82 trials and over 12,000 participants concluded that no serious adverse events were attributed to probiotics across the pooled evidence base.
Systematic reviewNo adverse effects seen in an 8-week human safety measure
In the same Bifidobacterium bifidum BGN4 trial, no adverse effects were observed over 8 weeks, with stable liver enzyme concentrations, blood pressure and gastrointestinal symptoms throughout.
Human RCTFrequently asked questions
What is CanPrev Pro-Biotik 15B and what does it do?
It's a capsule combining 5 real probiotic strains (Bifidobacterium bifidum HA-132, B. longum HA-135, Lactobacillus acidophilus HA-122, L. plantarum HA-119 and L. rhamnosus HA-111). It's a source of probiotics that promotes a favourable gut flora and helps support gastrointestinal health.
Does it really contain 15 billion CFU?
Yes - and more at the start. It's manufactured to a minimum of 40 billion CFU so that, based on quantified stability data, a guaranteed minimum of 15 billion CFU remains active through the labelled expiry date, not just at the time of manufacture.
Does it need to be refrigerated?
No. Pro-Biotik 15B is completely shelf-stable for use anytime, anywhere. It may be refrigerated to marginally slow potency loss, but this is not necessary.
How do I take it?
Adults take 1 or 2 capsules per day with food, or as directed by a health care practitioner.
How long does one bottle last?
Each bottle contains 60 capsules - at 1 capsule per day that's a 60-day supply, or a 30-day supply at 2 capsules per day.
Is it vegetarian?
Yes - it's encapsulated in a vegetable capsule. The label also carries a milk and soy contact caution because the product has come into contact with these allergens during manufacturing.
Who should use caution, or not use it?
Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment) or an allergy to dairy or soy products. Consult a health care practitioner before use if you have fever, vomiting, bloody diarrhea or severe abdominal pain, and stop use if digestive upset persists beyond 3 days.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support balanced gut flora with a shelf-stable, 5-strain probiotic
Get CanPrev Pro-Biotik 15B on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80020819. Source of probiotics that promotes a favourable gut flora and helps support gastrointestinal health. Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma) or are undergoing long-term corticosteroid treatment, or if you are allergic to dairy or soy products. Consult a health care practitioner prior to use if you have fever, vomiting, bloody diarrhea or severe abdominal pain. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, you should consult a health care practitioner on the use of this product. Consult a health care practitioner prior to use if you have fever, vomiting, bloody diarrhea or severe abdominal pain. Discontinue use and consult a health care practitioner if symptoms of digestive upset, such as diarrhea, occur, worsen or persist beyond 3 days. Do not use if seal is broken. Keep out of reach of children. Contraindications: Do not use if you have an immune-compromised condition such as AIDS or lymphoma, or if you are undergoing long-term corticosteroid treatment. Known Adverse Reactions: This product has come into contact with milk and soy. Do not use if you are allergic to dairy or soy products.
Indications
Recommended Use or Purpose: Pro-Biotik 15B is a source of probiotics that promotes a favourable gut flora and helps support gastrointestinal health.
Ingredients
Medicinal Ingredients (per capsule): Lactobacillus plantarum HA-119 4.95 Billion CFU. Lactobacillus rhamnosus HA-111 4.05 Billion CFU. Bifidobacterium bifidum HA-132 2.25 Billion CFU. Bifidobacterium longum HA-135 2.25 Billion CFU. Lactobacillus acidophilus HA-122 1.50 Billion CFU. Total: minimum 40 billion CFU at time of manufacture and 15 billion CFU at expiry. Non-medicinal ingredients: Ascorbic acid, fatty acids, silicon dioxide, potato starch, vegetable capsule. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults): Take one (1) or two (2) capsules per day with food, or as directed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.