CanPrev Post-Biotik Immunobiotics - Postbiotic Gut Support | 30 V-Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 capsule per day |
| Licensed Natural Health Product | NPN 80112753 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- DUAL-STRAIN HEAT-KILLED POSTBIOTIC: Each capsule provides 20 mg of Lacticaseibacillus paracasei MCC1849 and 10 mg of Immuno-LP20 (Lactiplantibacillus plantarum L-137) - both heat-killed, inactivated bacterial strains, not live-culture probiotics.
- HELPS SUPPORT AND MAINTAIN IMMUNE FUNCTION: Helps support and maintain immune function and helps reduce the incidence of cold-like symptoms.
- SHELF-STABLE, NO REFRIGERATION NEEDED: Because the bacteria are heat-killed rather than live, Post-Biotik Immunobiotics is shelf-stable at room temperature - no cold-chain storage required.
- SIMPLE ONCE-DAILY CAPSULE: Take just 1 capsule per day - a 30-capsule bottle provides a full 1-month supply.
- NON-GMO, GLUTEN-FREE, VEGAN: Formulated without gluten, soy, wheat, yeast, sugar, or artificial colours, flavours or preservatives.
- MADE IN CANADA: Formulated and made in Canada by CanPrev, licensed under Health Canada NPN 80112753.
Product Description
Post-Biotik Immunobiotics - Dual-Strain Heat-Killed Postbiotic for Immune & Gut Health
Each capsule provides 20 mg of Lacticaseibacillus paracasei MCC1849 and 10 mg of Immuno-LP20 (Lactiplantibacillus plantarum L-137) - both heat-killed (postbiotic), inactivated bacterial strains, not live-culture probiotics. Helps support and maintain immune function and helps reduce the incidence of cold-like symptoms. Licensed Natural Health Product. Licensed Natural Health Product NPN 80112753.
Chaque capsule fournit 20 mg de Lacticaseibacillus paracasei MCC1849 et 10 mg d'Immuno-LP20 (Lactiplantibacillus plantarum L-137) - deux souches bactériennes inactivées par la chaleur (postbiotiques), et non des probiotiques à culture vivante. Aide à maintenir et à soutenir les fonctions immunitaires et aide à réduire l'incidence des symptômes qui s'apparentent au rhume. Produit de santé naturel homologué. NPN 80112753.
Two Real Postbiotic Strains, One Daily Capsule
20mg Lacticaseibacillus paracasei MCC1849 + 10mg Immuno-LP20 - Heat-Killed, Non-GMO, Gluten-Free, Vegan
20mg Lacticaseibacillus paracasei MCC1849
A full 20 mg dose of this heat-killed postbiotic strain in every capsule, studied for its effects on immune cell activity.
10mg Immuno-LP20 (L-137)
10 mg of heat-killed Lactiplantibacillus plantarum L-137, a well-studied postbiotic ingredient known as Immuno-LP20.
What Post-Biotik Immunobiotics Supports
CanPrev Post-Biotik Immunobiotics pairs two heat-killed postbiotic strains - here is what each is formulated to support.
Immune Function Support
Helps support and maintain immune function, and helps reduce the incidence of cold-like symptoms.
Gut Microbiome Balance
Postbiotics provide ready-to-use compounds - like short-chain fatty acids - that nourish beneficial gut bacteria, supporting a balanced microbiome.
Shelf-Stable, Heat-Killed Formula
Because the bacteria are heat-killed rather than live, this formula is inherently shelf-stable - no refrigeration required.
Simple Once-Daily Routine
One easy-to-swallow capsule per day - a 30-capsule bottle provides a full 1-month supply.
CanPrev Post-Biotik Immunobiotics: Supplement Facts
Product Facts
- Lacticaseibacillus paracasei MCC184920 mg
- Immuno-LP20 Lactiplantibacillus plantarum L-13710 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Acacia (Fibregum), vegetable-grade magnesium stearate, ascorbic acid, maltodextrine, vegetable capsule.
Recommended Use or Purpose: Helps support and maintain immune function. Helps reduce the incidence of cold-like symptoms.
Recommended Dose (Adults): Take one (1) capsule per day, or as directed by a health care practitioner. Take at least 2-3 hours before or after antibiotics.
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use especially if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Stop use and consult a health care practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen and/or persist beyond 3 days. Do not use if seal is broken. Keep out of reach of children. Contraindications: Do not use this product if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Known Adverse Reactions: Do not use this product if you have a milk allergy.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Info-produit
- Lacticaseibacillus paracasei MCC184920 mg
- Immuno-LP20 Lactiplantibacillus plantarum L-13710 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Acacia (Fibregum), stéarate de magnésium de grade végétal, acide ascorbique, maltodextrine, capsule végétale.
Usage ou fins recommandés : Aide à maintenir et à soutenir les fonctions immunitaires. Aide à réduire l'incidence des symptômes qui s'apparentent au rhume.
Dose recommandée (adultes) : Prendre une (1) capsule par jour, ou selon les directives d'un praticien de soins de santé. Prendre au moins 2 à 3 heures avant ou après la prise d'antibiotiques.
Mises en garde et avertissements : Comme pour tout produit de santé naturel, consultez un praticien de soins de santé avant l'usage surtout si vous souffrez de fièvre, de vomissements, de diarrhée sanglante ou de douleurs abdominales intenses. Cessez l'utilisation et consultez un praticien de soins de santé si des symptômes de troubles digestifs (par ex., diarrhée) se manifestent, s'aggravent et/ou persistent au-delà de 3 jours. Ne pas utiliser si le sceau est brisé. Tenir hors de la portée des enfants. Contre-indications : Ne pas utiliser ce produit si vous souffrez d'un déficit immunitaire (par ex., sida, lymphome, patients subissant un traitement prolongé aux corticostéroïdes). Réactions indésirables connues : Ne pas utiliser ce produit si vous êtes allergique au lait.
NPN 80112753
Support your immune system and gut, heat-killed and shelf-stable
Get CanPrev Post-Biotik Immunobiotics on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Post-Biotik Immunobiotics
A real, dosed dual-strain heat-killed postbiotic - not a proprietary blend - for immune and gut health support.
20mg MCC1849 + 10mg Immuno-LP20
A real, dosed combination of two clinically studied heat-killed postbiotic strains in every capsule - not a proprietary blend.
Helps support immune function
Helps support and maintain immune function, and helps reduce the incidence of cold-like symptoms.
Shelf-stable, heat-resistant formula
Heat-killed (postbiotic) bacteria are inherently more stable than live probiotics - no refrigeration needed.
Premium Canadian brand
CanPrev, formulated and made in Canada. NPN 80112753.
How to use it
Take 1 capsule daily
Adults take one (1) capsule per day, or as directed by a health care practitioner.
Space it from antibiotics
Take at least 2-3 hours before or after taking antibiotics.
Watch for digestive upset
Consult a health care practitioner before use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain; stop use if digestive upset persists beyond 3 days.
Know the contraindications
Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, long-term corticosteroid treatment) or a milk allergy.
What the research says about postbiotics, MCC1849 and Immuno-LP20
Educational summaries of published research on postbiotics generally and on the two strains in this formula - not claims about this finished product. CanPrev Post-Biotik Immunobiotics' claim is the authorized use under NPN 80112753.
Postbiotics are officially defined and distinct from probiotics
The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement defines a postbiotic as a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host - distinct from live, viable probiotic organisms.
Consensus statementPostbiotic proteins support gut barrier activity
A review of postbiotic-derived bacterial proteins (including p40 and p75) found they support intestinal barrier activity and protect epithelial tight junctions, suggesting a mechanism for gut-lining support even without live bacteria.
ReviewPostbiotics act through defined pathways without live-organism risk
A review of postbiotics and paraprobiotics found these non-viable microbial derivatives act through defined immune-metabolic pathways that enhance epithelial barrier function and modulate inflammatory signalling, without the infection risk or viability concerns of live probiotics.
Review24-week trial found fewer cold-like symptom days
In a randomized, double-blind, placebo-controlled trial of 200 healthy adults, 24 weeks of heat-killed Lacticaseibacillus paracasei MCC1849 significantly reduced the number of days of stuffy nose and cold-like symptoms compared with placebo.
Human RCTImproved flu vaccine antibody response in the oldest-old
In a randomized, double-blind trial in two nursing homes, heat-killed MCC1849 given before influenza vaccination did not significantly change antibody responses overall, but among participants aged 85 and older, antibody responses that were impaired in the placebo group were improved.
Human RCT4-week trial shows the immune mechanism behind the effect
A randomized, double-blind, placebo-controlled trial of 100 healthy adults found that 4 weeks of heat-killed MCC1849 significantly increased CD86 expression on plasmacytoid dendritic cells and interferon-alpha, -beta and -gamma gene expression versus placebo, offering a mechanism for its symptom benefits.
Human RCTDirectly activates human immune cells in the lab
Heat-killed MCC1849 cocultured with human peripheral blood mononuclear cells was phagocytosed by, and significantly increased activation markers CD86 and HLA-DR on, plasmacytoid dendritic cells - a key first-responder immune cell type.
Mechanistic studyBoosted gut antibody production in a mouse model
Orally administered heat-killed MCC1849 increased antigen-specific IgA secretion in the small intestine, serum and lungs of mice, and increased the proportion of IgA-producing B cells and follicular helper T cells in gut-associated lymphoid tissue.
Preclinical studyA decade of research on how MCC1849 works
A review of heat-killed MCC1849 research describes its immunomodulatory effects as working through activation of dendritic cells and other innate immune pathways, and discusses its use as a stable, food-compatible postbiotic ingredient.
ReviewHigh-dose 4-week human trial found no adverse events
In 20 healthy adults given 250 billion heat-killed MCC1849 cells per day for 4 weeks - many times a typical dose - no adverse events and no clinically meaningful changes in blood pressure, blood or urine parameters were observed.
Human safety studyImmuno-LP20 safety confirmed at high dose and long term
Human studies of Immuno-LP20 (heat-killed Lactiplantibacillus plantarum L-137) found no adverse events at a high dose (50mg/day for 4 weeks) or with long-term daily use (10mg/day for 12 months), with no signs of immune exhaustion.
Human safety studyProbiotic-family caution is real for certain conditions
A clinical review of probiotic use in gastrointestinal disorders notes that, while generally well-tolerated, caution has to be exercised in immunocompromised and critically ill individuals - consistent with this product's own labelled contraindication.
ReviewOriginal 12-week trial found improved immune-cell activity
In a randomized, double-blind, placebo-controlled trial of 60 healthy adults, 10mg/day of heat-killed L-137 for 12 weeks significantly increased T-cell proliferation and the Th1:Th2 immune balance versus placebo, at the same dose used in this product.
Human RCT12-week trial showed benefits for skin hydration
In a randomized, placebo-controlled trial of 80 adults, daily heat-killed L-137 improved skin water content and reduced water loss versus placebo over 12 weeks, particularly in participants with drier skin - an example of the gut-body connection.
Human RCTImmune signalling from L-137 traced to a specific pathway
Heat-killed L-137 was found to upregulate hyaluronic acid production in skin cells via interferon-gamma and TNF-alpha signalling in mouse studies, illustrating one molecular pathway by which this heat-killed bacterium influences the body beyond the gut.
Preclinical studyPostbiotics help crowd out unwanted bacteria
A review of probiotic-host immune crosstalk describes how beneficial bacteria and their components stimulate antimicrobial peptide production and can inhibit quorum sensing in competing microbes, helping support a balanced gut microbial community.
ReviewMicrobial metabolites support antioxidant and barrier defenses
A review of probiotics, synbiotics and microbial metabolites describes how bioactive compounds from beneficial bacteria help regulate the body's own antioxidant enzyme systems and reinforce epithelial barrier function as part of a broader host-microbe partnership.
ReviewL-137 shown to calm inflammation in a diet-induced model
In mice fed a high-fat diet, heat-killed L-137 reduced weight gain and downregulated inflammation-related genes in fat tissue, suggesting a broader anti-inflammatory mechanism for this heat-killed bacterium beyond its immune effects.
Preclinical studyLarge network meta-analysis of 100,000+ adults
A 2025 systematic review and network meta-analysis of 107 trials in over 101,000 adults found multi-strain probiotics among the more effective nutritional supplements for reducing the incidence, duration and severity of respiratory tract infections, with no increase in adverse events.
Network meta-analysisMeta-analysis: modest but real reduction in infection days
A systematic review and meta-analysis of 42 trials in over 9,000 non-elderly adults found orally ingested probiotics modestly reduced the risk, total days, duration and severity of respiratory tract infections compared with placebo.
Meta-analysisFermented probiotic dairy linked to lower cold risk
A meta-analysis of 22 randomized trials in over 10,000 participants found probiotic fermented dairy products were associated with a significantly lower risk of respiratory tract infections, including a lower risk of the common cold specifically.
Meta-analysisQuality-of-life scores improved alongside immune markers
In the same 12-week trial establishing Immuno-LP20's immune effects, participants' self-rated health-related quality-of-life scores improved significantly more in the active group than placebo by week 8.
Human RCTLong-term use linked to a healthier gut microbial ratio
In the same long-term Immuno-LP20 safety study, 12 months of daily use was associated with a significantly lower Firmicutes-to-Bacteroidetes ratio and higher fecal short-chain fatty acid levels versus baseline - both markers linked to gut balance.
Human safety studyEven at high doses, standard health markers stayed normal
In the same high-dose MCC1849 safety trial, anthropometric measurements, blood pressure, and blood and urine chemistry all stayed within normal ranges throughout the 4-week study, reinforcing the ingredient's tolerability.
Human safety studyFrequently asked questions
What is CanPrev Post-Biotik Immunobiotics and what does it do?
It's a capsule combining 20 mg of Lacticaseibacillus paracasei MCC1849 and 10 mg of Immuno-LP20 (Lactiplantibacillus plantarum L-137) per capsule. It helps support and maintain immune function and helps reduce the incidence of cold-like symptoms.
Is this a probiotic or a postbiotic?
It's a postbiotic. Both strains are heat-killed (inactivated) bacteria, not live cultures - CanPrev's own labelling describes it as 'Postbiotics · Microbe-Sourced · Heat-Killed Bacteria.'
How do I take it?
Adults take 1 capsule per day, or as directed by a health care practitioner. Take at least 2-3 hours before or after antibiotics.
How long does one bottle last?
Each bottle contains 30 capsules - at the recommended dose of 1 capsule per day, that's a full 1-month supply.
Is it vegan?
Yes - the capsule and formula are plant-derived (vegetable capsule, acacia, vegetable-grade magnesium stearate). The label also carries a milk allergy caution, because the postbiotic strains are cultured using dairy-based fermentation media; there is no dairy ingredient in the finished formula.
Who should use caution, or not use it?
Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment) or a milk allergy. Consult a health care practitioner before use if you have a fever, vomiting, bloody diarrhea or severe abdominal pain, and stop use if digestive upset persists beyond 3 days.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support your immune system and gut, heat-killed and shelf-stable
Get CanPrev Post-Biotik Immunobiotics on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80112753. Helps support and maintain immune function. Helps reduce the incidence of cold-like symptoms. Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment) or a milk allergy. Consult a health care practitioner prior to use especially if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use especially if you have a fever, vomiting, bloody diarrhea or severe abdominal pain. Stop use and consult a health care practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen and/or persist beyond 3 days. Do not use if seal is broken. Keep out of reach of children. Contraindications: Do not use this product if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Known Adverse Reactions: Do not use this product if you have a milk allergy.
Indications
Recommended Use or Purpose: Helps support and maintain immune function. Helps reduce the incidence of cold-like symptoms.
Ingredients
Medicinal Ingredients (per capsule): Lacticaseibacillus paracasei MCC1849 20 mg. Immuno-LP20 (Lactiplantibacillus plantarum L-137) 10 mg. Non-medicinal ingredients: Acacia (Fibregum), vegetable-grade magnesium stearate, ascorbic acid, maltodextrine, vegetable capsule. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults): Take one (1) capsule per day, or as directed by a health care practitioner. Take at least 2-3 hours before or after antibiotics.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.