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Health Canada NPN 80017016 Calcium, Magnesium, Zinc, Boron, D3 & K1 Gentle Magnesium Bisglycinate · Vegetable Capsules Made in Canada · 30-Day Supply
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CanPrev Osteo Prolong - Calcium, Magnesium, Zinc, D3 & K1 | 120 Caps

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$37.62 CAD ($0.31 / capsule)
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BrandCanPrev
Serving4 capsules daily (200mg elemental calcium, 86mg elemental magnesium)
Licensed Natural Health ProductNPN 80017016
Quality StandardsMade in Canada
CountryMade in Canada Made in Canada

About this item

  • COMPLETE BONE-BUILDING FORMULA: Calcium, magnesium, zinc, boron, vitamin D3 and vitamin K1 combine in one daily formula to help in the development and maintenance of strong bones and teeth.
  • GENTLE MAGNESIUM BISGLYCINATE: Magnesium bisglycinate is a chelated, easy-to-digest form of magnesium, formulated to be gentle on the stomach for consistent daily use.
  • DUAL-SOURCE CALCIUM: 200mg of calcium per capsule from a blend of calcium citrate and calcium carbonate helps the body maintain strong bones and teeth as part of a healthy diet.
  • VITAMIN D3 & K1 SYNERGY: Vitamin D3 and vitamin K1 are included alongside calcium and magnesium to round out a complete daily bone-support formula.
  • MADE IN CANADA: Formulated and made in Canada by CanPrev, licensed under Health Canada NPN 80017016.
  • GMO-FREE, NO FILLERS: 120 vegetable capsules with no artificial colours, flavours or preservatives, and free of gluten, dairy, wheat and sugar.
  • SIMPLE DAILY DOSING: Adults take 2 capsules, 2 times per day (4 capsules daily) with food - a 30-day supply per bottle.

Product Description

Osteo Prolong - Calcium, Magnesium, Zinc, Boron, Vitamin D3 & K1 for Bone Support

CanPrev Osteo Prolong

A complete daily bone-support formula: 200mg calcium (citrate and carbonate) and 86mg gentle magnesium bisglycinate, paired with zinc, boron, vitamin D3 and vitamin K1 - formulated to help in the development and maintenance of strong bones and teeth. Licensed Natural Health Product NPN 80017016.

Une formule complète de soutien osseux quotidien : 200 mg de calcium (citrate et carbonate) et 86 mg de magnésium bisglycinate doux pour l'estomac, avec du zinc, du bore, de la vitamine D3 et de la vitamine K1 - conçue pour aider au développement et au maintien d'os et de dents solides. Produit de santé naturel homologué. NPN 80017016.

Osteo Prolong lifestyle
CanPrev Osteo Prolong
200mg Calcium + 86mg Magnesium Bisglycinate · 6 Bone Nutrients

Six Nutrients, One Daily Bone-Support Formula

200mg Calcium (Citrate + Carbonate), 86mg Magnesium Bisglycinate, Zinc, Boron, Vitamin D3 & K1 - Vegan Capsules, Gluten-Free, Non-GMO

200mg Calcium, Gently Absorbed

A dual-source blend of calcium citrate and calcium carbonate delivers 200mg of calcium per capsule to help maintain strong bones and teeth.

86mg Chelated Magnesium Bisglycinate

Magnesium bisglycinate is formulated to be gentle on digestion, working alongside calcium, zinc, boron, vitamin D3 and K1 in one complete formula.

What's Inside Every Capsule

Osteo Prolong combines six nutrients that each play a role in bone health - here is what's inside every capsule.

Calcium (Calcium Citrate, Calcium Carbonate)

A dual-source blend of calcium citrate and calcium carbonate that helps in the development and maintenance of bones and teeth.

200 mg per capsule

Magnesium (Magnesium Bisglycinate, Magnesium Oxide)

A chelated bisglycinate form paired with magnesium oxide, supporting normal muscle function and working alongside calcium in bone metabolism.

86 mg per capsule

Zinc (Zinc Citrate)

A well-absorbed citrate form of zinc studied for its role in bone-cell activity and tissue formation.

3 mg per capsule

Boron (Boron Citrate)

A trace mineral studied for its role in bone and mineral metabolism.

175 mcg per capsule

Vitamin K1 (Phytonadione)

A form of vitamin K involved in the carboxylation of bone matrix proteins such as osteocalcin.

30 mcg per capsule

Vitamin D3 (Cholecalciferol)

A highly bioactive form of vitamin D that works with calcium to support bone and tooth maintenance.

6.25 mcg (250 IU) per capsule

CanPrev Osteo Prolong: Supplement Facts

CanPrev™Osteo Prolong
English

Supplement Facts

  • Calcium (calcium citrate, calcium carbonate) per capsule200 mg
  • Magnesium (magnesium bisglycinate, magnesium oxide) per capsule86 mg
  • Zinc (zinc citrate) per capsule3 mg
  • Boron (boron citrate) per capsule175 mcg
  • Vitamin K1 (phytonadione) per capsule30 mcg
  • Vitamin D3 (cholecalciferol) per capsule6.25 mcg (250 IU)

Non-Medicinal Ingredients: Non-medicinal ingredients: Glycine, hypromellose, magnesium stearate. GMO free, no binders, no fillers; free of gluten, dairy, wheat, sugar, artificial colours, flavours or preservatives. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.

Recommended Dose (Adults 19 years and older): Take 2 capsules, 2 times per day, with food, a few hours before or after other medications or natural health products. For optimal results, take daily.

Cautions and Warnings: Ask a healthcare practitioner prior to use if you are taking blood thinners or if you have a medical condition. Do not use if the safety seal is broken. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Fiche produit

  • Calcium (citrate de calcium, carbonate de calcium) par capsule200 mg
  • Magnésium (bisglycinate de magnésium, oxyde de magnésium) par capsule86 mg
  • Zinc (citrate de zinc) par capsule3 mg
  • Bore (citrate de bore) par capsule175 mcg
  • Vitamine K1 (phytonadione) par capsule30 mcg
  • Vitamine D3 (cholécalciférol) par capsule6.25 mcg (250 IU)

Ingrédients non médicinaux : Ingrédients non médicinaux : Glycine, hypromellose, stéarate de magnésium. Sans OGM, ni agents liants ou agents de remplissage; sans gluten, produits laitiers, blé, sucre, colorants, arômes ou agents de conservation artificiels. Les ingrédients non médicinaux peuvent changer - lisez et suivez toujours l'étiquette pour des renseignements exacts sur les ingrédients, les mises en garde et les allergènes.

Usage ou fins recommandés : Aide au développement et au maintien des os et des dents.

Posologie recommandée (adultes de 19 ans et plus) : Prendre 2 capsules, 2 fois par jour, avec de la nourriture, quelques heures avant ou après la prise d'autres médicaments ou produits de santé naturels. Pour des résultats optimaux, prendre quotidiennement.

Mises en garde et précautions : Consultez un praticien de soins de santé avant l'usage si vous prenez des anticoagulants ou si vous avez un problème de santé. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.

NPN 80017016

200mg Calcium · 86mg Magnesium BisglycinateZinc · Boron · Vitamin D3 & K1120 Veg Capsules · 30-Day SupplyMade in Canada

Support strong bones and teeth, the complete way

Get CanPrev Osteo Prolong on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev Osteo Prolong

A complete calcium, magnesium, zinc, boron, D3 and K1 formula with gentle chelated magnesium bisglycinate - formulated to help maintain strong bones and teeth.

200mg Calcium, dual-source

Calcium citrate and calcium carbonate combine to help in the development and maintenance of bones and teeth.

Gentle magnesium bisglycinate

86mg of chelated magnesium bisglycinate (plus magnesium oxide) is formulated to be gentle on digestion.

Complete with D3, K1, zinc & boron

Vitamin D3, vitamin K1, zinc and boron round out a complete daily bone-support formula.

Premium Canadian brand

CanPrev, formulated and made in Canada. NPN 80017016.

Inside every capsule

A complete bone-building blend - 200mg calcium (citrate & carbonate), 86mg gentle magnesium bisglycinate, plus zinc, boron, vitamin D3 and vitamin K1 - formulated to help maintain strong bones and teeth.

Calcium (Calcium Citrate, Calcium Carbonate) 200 mg per capsuleMagnesium (Magnesium Bisglycinate, Magnesium Oxide) 86 mg per capsuleZinc (Zinc Citrate) 3 mg per capsuleBoron (Boron Citrate) 175 mcg per capsuleVitamin K1 (Phytonadione) 30 mcg per capsuleVitamin D3 (Cholecalciferol) 6.25 mcg (250 IU) per capsule

How to use it

Take 2 capsules, twice daily

Adults (19 years and older) take 2 capsules, 2 times per day (4 capsules total), or as directed by a health care practitioner.

Take with food

Take with food for comfort and consistency.

Space out other medications

Take a few hours before or after other medications or natural health products.

Consult a practitioner if unsure

Ask a health care practitioner prior to use if you are taking blood thinners or have a medical condition.

What the research says about this formula's nutrients

Educational summaries of published research on calcium, magnesium, zinc, boron, vitamin D3 and vitamin K1 individually, and on the specific chelated/citrate forms used here; not claims about this finished product. CanPrev Osteo Prolong's own claim is the authorized use under NPN 80017016.

Calcium & Bone Mineral Density

Calcium supplementation produced small, non-progressive increases in bone density

A systematic review and meta-analysis of 59 randomized controlled trials found that both dietary calcium and calcium supplements increased bone mineral density by roughly 0.6-1.8% at various skeletal sites, though the size of the increase did not keep growing with longer treatment.

Meta-analysis
Tai et al., BMJ (2015)
Calcium & Bone Mineral Density

Evidence that calcium supplements reduce fracture risk is weak and inconsistent

A systematic review of dietary calcium, dairy intake and calcium supplement trials found no association between dietary calcium intake and fracture risk, and only weak, inconsistent evidence that calcium supplements reduce fracture risk in the general population.

Systematic Review
Bolland et al., BMJ (2015)
Calcium & Bone Mineral Density

Calcium, with or without vitamin D, reduced fractures and bone loss in a large meta-analysis

A meta-analysis of randomized trials in people aged 50 and older found that calcium, or calcium in combination with vitamin D, was associated with reduced bone loss and a reduction in fracture risk, with better results in trials with higher treatment compliance.

Meta-analysis
Tang et al., Lancet (2007)
Calcium Citrate, Carbonate & Absorption

An early calcium citrate-malate formulation absorbed better than calcium carbonate

In both rat and human absorption studies using a double-isotope method, a soluble calcium citrate-malate delivery system was absorbed significantly better than calcium carbonate or milk, showing that calcium salt form can meaningfully affect bioavailability.

Human & Animal Study
Smith et al., Calcified Tissue International (1987)
Calcium Citrate, Carbonate & Absorption

Calcium citrate showed higher bioavailability than calcium carbonate in a randomized crossover trial

In a double-blind, randomized crossover trial, calcium citrate produced a higher blood calcium area-under-the-curve and a greater reduction in parathyroid hormone than calcium carbonate, indicating superior relative absorption.

Human RCT
Hany et al., Surgery for Obesity and Related Diseases (2024)
Calcium Citrate, Carbonate & Absorption

Both calcium carbonate and calcium citrate malate improved bone mineral density in osteopenia patients

A randomized open-label study in osteopenia patients found that calcium carbonate and calcium citrate malate both produced significant improvements in bone mineral density T-scores over 8 weeks, alongside a newer calcium lysinate form.

Human RCT
Shankar et al., Journal of Orthopaedic Case Reports (2018)
Vitamin D3 & Calcium Absorption

Vitamin D3 raised blood vitamin D levels more effectively than vitamin D2

A systematic review and meta-analysis of randomized controlled trials directly comparing the two forms found that vitamin D3 was significantly more efficacious than vitamin D2 at raising serum 25-hydroxyvitamin D concentrations, particularly with bolus dosing.

Meta-analysis
Tripkovic et al., American Journal of Clinical Nutrition (2012)
Vitamin D3 & Calcium Absorption

Vitamin D governs how efficiently the intestine absorbs dietary calcium

A review of intestinal calcium absorption describes how activated vitamin D binds the intestinal vitamin D receptor to enable calcium uptake when dietary calcium is low, a process essential for bone mineralization and known to decline with aging and menopause.

Review
Fleet, Nutrients (2022)
Vitamin D3 & Calcium Absorption

Combined calcium and vitamin D supplementation supported bone outcomes in postmenopausal osteoporosis

A systematic review and meta-analysis of trials in postmenopausal women with osteoporosis found that combined calcium and vitamin D supplementation was associated with favorable effects on bone remodeling markers compared with calcium or vitamin D given alone.

Meta-analysis
Liu et al., Food & Function (2020)
Vitamin K1 & Bone Health

Vitamin K is a cofactor for proteins involved in bone metabolism

A review of vitamin K and bone health describes vitamin K's role as a cofactor in the carboxylation of osteocalcin and other bone matrix proteins, and summarizes observational and interventional evidence on vitamin K status and skeletal outcomes.

Review
Hamidi et al., Journal of Clinical Densitometry (2013)
Vitamin K1 & Bone Health

Vitamin K's role in adult bone health remains an active research area

A review of vitamin K and bone health in adult humans summarizes evidence from observational studies and clinical trials, noting that while vitamin K is required for carboxylation of bone proteins like osteocalcin, its direct effect on fracture prevention is less consistently established than for calcium and vitamin D.

Review
Bügel, Vitamins and Hormones (2008)
Vitamin K1 & Bone Health

Dietary vitamin K1 intake was not associated with bone density or fracture risk in one Danish cohort

In a population-based cohort of 2,016 perimenopausal Danish women followed for up to 10 years, dietary vitamin K1 intake was not associated with bone mineral density at the femoral neck or lumbar spine, nor with fracture risk - illustrating that evidence for individual nutrients can be mixed.

Cohort Study
Rejnmark et al., Osteoporosis International (2006)
Magnesium & Bone/Muscle Function

Higher magnesium intake was linked to greater hip bone density in older adults

A systematic review and meta-analysis of cohort and cross-sectional studies in adults 60 and older found a significant positive association between magnesium intake and hip bone mineral density, though evidence for other skeletal sites and fracture outcomes remains limited.

Meta-analysis
Groenendijk et al., Bone (2021)
Magnesium & Bone/Muscle Function

Magnesium plays a role in muscle contraction, nerve conduction, and hundreds of metabolic reactions

A review of magnesium's physiological roles describes its involvement in energy metabolism, protein synthesis, muscle contraction, and neuromuscular excitability, noting that the skeleton itself serves as a magnesium reservoir when dietary intake is inadequate.

Review
Laires et al., Frontiers in Bioscience (2004)
Magnesium & Bone/Muscle Function

Calcium, magnesium and vitamin D are highlighted together in research on age-related bone and muscle loss

A review of osteosarcopenic adiposity syndrome - the combined loss of bone, muscle and healthy body composition with aging - identifies calcium, magnesium and vitamin D status among the key modifiable nutritional factors associated with musculoskeletal health in older adults.

Review
Ilich et al., Proceedings of the Nutrition Society (2021)
Zinc & Bone/Tissue Formation

Zinc status has been linked to bone mineral density across multiple study types

A narrative review of 16 studies on blood zinc, dietary zinc intake and zinc supplementation found that low zinc intake (under 3 mg/day) may be a risk factor for osteopenia and osteoporosis, and that zinc supplementation showed benefits for maintaining bone mineral density.

Review
Rondanelli et al., Acta Ortopédica Mexicana (2021)
Zinc & Bone/Tissue Formation

Zinc stimulates bone-building cells while suppressing bone-resorbing cells

A mechanistic study found that zinc promotes osteoblast (bone-forming cell) differentiation and mineralization while suppressing osteoclast (bone-resorbing cell) differentiation, acting in part by antagonizing NF-kB activation driven by inflammatory signaling.

In Vitro Study
Yamaguchi & Weitzmann, Molecular and Cellular Biochemistry (2011)
Zinc & Bone/Tissue Formation

Higher dietary zinc intake was associated with lower odds of osteoporosis in a large cohort

An analysis of over 5,000 elderly hypertensive patients from U.S. national health survey data found that dietary zinc intake meeting the recommended daily allowance was positively correlated with bone mineral density at the hip and femoral neck, and associated with lower odds of osteoporosis.

Cross-sectional Study
Chen et al., Frontiers in Nutrition (2024)
Boron & Bone/Mineral Metabolism

Boron deficiency has been linked to bone-metabolism disorders in a comprehensive review

A comprehensive review of boron's biological roles found that boron deficiency has been correlated with lower immune function and higher incidence of osteoporosis, and that boron supplementation has been shown to enhance bone density and support bone metabolism in animal studies.

Review
Abdelnour et al., Journal of Trace Elements in Medicine and Biology (2018)
Boron & Bone/Mineral Metabolism

Boric acid supplementation improved bone-formation markers in growing animals

A controlled feeding study in growing calves found that boric acid supplementation at a moderate dose (200 ppm boron) improved blood markers associated with bone formation, including osteocalcin and bone-specific alkaline phosphatase, compared with an unsupplemented control diet.

Controlled Trial (Animal)
Singh et al., Journal of Trace Elements in Medicine and Biology (2020)
Boron & Bone/Mineral Metabolism

Boron supplementation supported calcium homeostasis and bone metabolism around calving in dairy animals

A controlled feeding study in peripartum buffaloes found that boron supplementation at 200 and 400 ppm increased plasma calcium, magnesium and osteocalcin levels, and was associated with markers indicating improved bone metabolism during a physiologically demanding period.

Controlled Trial (Animal)
Sharma et al., Journal of Trace Elements in Medicine and Biology (2020)
Mineral Form & Bioavailability

Zinc citrate was absorbed as well as zinc gluconate, and better than zinc oxide, in a controlled trial

Using a double-isotope tracer method in healthy adults, researchers found that fractional zinc absorption from zinc citrate (61.3%) was not different from zinc gluconate (60.9%), and both were significantly better absorbed than zinc oxide (49.9%).

Human RCT
Wegmüller et al., Journal of Nutrition (2013)
Mineral Form & Bioavailability

Different magnesium supplement forms showed distinct absorption and side-effect profiles in a clinical study

A double-blind, randomized crossover study comparing magnesium oxide, magnesium citrate, magnesium bisglycinate and a microencapsulated form found that each source produced a different pattern and duration of plasma magnesium increase, and that magnesium sources varied in gastrointestinal side effects such as increased motility.

Human RCT
Pajuelo et al., Nutrients (2024)
Mineral Form & Bioavailability

Short-term supplementation with different magnesium salts affected ionized and total magnesium differently

A study of magnesium oxide, citrate and carbonate supplements in healthy young adults over 10 days found each form produced distinct effects on ionized versus total serum magnesium, underscoring that the chemical form of a mineral supplement can meaningfully change its physiological handling.

Human Study
Ivanovic et al., Biometals (2022)

Frequently asked questions

What is CanPrev Osteo Prolong and what does it do?

It's a complete bone-support formula with 200mg calcium (from calcium citrate and calcium carbonate), 86mg magnesium (from magnesium bisglycinate and magnesium oxide), plus zinc, boron, vitamin D3 and vitamin K1. It helps in the development and maintenance of bones and teeth.

How do I take it?

Adults (19 years and older) take 2 capsules, 2 times per day (4 capsules total daily), with food, a few hours before or after other medications or natural health products.

How long does one bottle last?

Each bottle contains 120 vegetable capsules - a 30-day supply at the recommended dose of 4 capsules per day.

Why magnesium bisglycinate instead of only magnesium oxide?

Magnesium bisglycinate is a chelated form formulated to be gentle on the digestive system, which is why CanPrev pairs it with magnesium oxide in this formula rather than using magnesium oxide alone.

Why does this formula include zinc and boron alongside calcium and magnesium?

Zinc and boron are trace minerals studied for their roles in bone-cell activity and mineral metabolism, rounding out a more complete bone-support profile than a calcium-only supplement.

Is it vegan?

Yes - Osteo Prolong is formulated in vegetable capsules and is free of gluten, dairy, wheat, sugar, and artificial colours, flavours or preservatives.

Who should use caution, or not use it?

Ask a health care practitioner prior to use if you are taking blood thinners or have a medical condition. Do not use if the safety seal is broken. Keep out of reach of children.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

200mg Calcium · 86mg Magnesium BisglycinateZinc · Boron · Vitamin D3 & K1120 Veg Capsules · 30-Day SupplyMade in Canada

Support strong bones and teeth, the complete way

Get CanPrev Osteo Prolong on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80017016. Osteo Prolong helps in the development and maintenance of bones and teeth. The research summaries below concern the individual nutrients in this formula generally and are educational - they are not claims about this finished product. Read and follow the label. As with any natural health product, consult a health care practitioner on the use of this product, especially if you are taking blood thinners or have a medical condition. Do not use if the safety seal is broken. Results may vary.

Important information

Safety Information

Cautions and Warnings: Ask a healthcare practitioner prior to use if you are taking blood thinners or if you have a medical condition. Do not use if the safety seal is broken. Keep out of reach of children.

Indications

Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.

Ingredients

Medicinal ingredients (per capsule): Calcium (calcium citrate, calcium carbonate) 200 mg, Magnesium (magnesium bisglycinate, magnesium oxide) 86 mg, Zinc (zinc citrate) 3 mg, Boron (boron citrate) 175 mcg, Vitamin K1 (phytonadione) 30 mcg, Vitamin D3 (cholecalciferol) 6.25 mcg (250 IU). Non-medicinal ingredients: Glycine, hypromellose, magnesium stearate. GMO free, no binders, no fillers; free of gluten, dairy, wheat, sugar, artificial colours, flavours or preservatives. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults 19 years and older): Take 2 capsules, 2 times per day, with food, a few hours before or after other medications or natural health products. For optimal results, take daily.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.