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Health Canada NPN 80089237 600mg NAC + 70mg L-Glycine + 20mcg Selenium per Capsule Vegan · Non-GMO · Gluten-Free 120 Vegan Capsules · 120-Day Supply
NAC+ N-Acetyl-L-CysteineNAC+ N-Acetyl-L-Cysteine - benefits and key ingredients NAC+ N-Acetyl-L-Cysteine - lifestyleNAC+ N-Acetyl-L-Cysteine - ingredientsNAC+ N-Acetyl-L-Cysteine - supplement facts panel

CanPrev NAC+ N-Acetyl-L-Cysteine - with Glycine & Selenium | 120 Caps

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$29.99 CAD ($0.25 / capsule)
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BrandCanPrev
Serving1 Capsule
Licensed Natural Health ProductNPN 80089237
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • POTENT NAC SUPPORT: Each vegan capsule delivers 600mg of N-Acetyl-L-Cysteine (NAC), a stable form of the amino acid cysteine and the rate-limiting building block the body uses to make glutathione, its main intracellular antioxidant.
  • ENHANCED WITH L-GLYCINE AND SELENIUM: Formulated with 70mg of L-Glycine (another glutathione-precursor amino acid) and 20mcg of Selenium (Albion™ Selenium Glycinate), an essential cofactor for the glutathione peroxidase antioxidant enzyme family.
  • SOURCE OF ANTIOXIDANTS: The Health Canada-authorized use of this product is that it is a source of antioxidants that helps protect against oxidative stress.
  • PURE & HIGH-QUALITY: Crafted by CanPrev, a Canadian brand recognized for its dedication to purity and quality, with no unnecessary fillers or artificial additives.
  • VEGAN, EASY TO SWALLOW: 120 vegan capsules in a convenient once-daily dose - a simple way to work NAC, L-Glycine and Selenium into a daily wellness routine.
  • CONVENIENT 120-DAY SUPPLY: One bottle of 120 capsules provides a full 120-day supply at the labelled adult dose of 1 capsule per day.

Product Description

NAC+ - 600mg NAC with L-Glycine and Selenium

CanPrev NAC+ N-Acetyl-L-Cysteine

CanPrev NAC+ delivers 600mg of N-Acetyl-L-Cysteine per vegan capsule, enhanced with 70mg of L-Glycine and 20mcg of Selenium (Albion™ Selenium Glycinate). Source of antioxidants that helps protect against oxidative stress. Licensed Natural Health Product, NPN 80089237. Licensed Natural Health Product NPN 80089237.

CanPrev NAC+ offre 600 mg de N-acétylcystéine par capsule végétale, enrichi de 70 mg de L-glycine et de 20 mcg de sélénium (glycinate de sélénium Albion™). Source d'antioxydants qui aide à protéger contre le stress oxydatif. Produit de santé naturel homologué, NPN 80089237.

NAC+ N-Acetyl-L-Cysteine lifestyle
CanPrev NAC+ N-Acetyl-L-Cysteine
600mg NAC + 70mg L-Glycine + 20mcg Selenium

Three Real Actives, One Vegan Capsule

600mg NAC · 70mg L-Glycine · 20mcg Selenium - Vegan, Non-GMO, Gluten-Free

A Glutathione-Precursor Pairing

NAC and L-Glycine are both amino-acid precursors the body uses to synthesize glutathione, its main intracellular antioxidant - combined in one capsule rather than NAC alone.

Selenium for the Antioxidant Enzyme System

Selenium (Albion™ Selenium Glycinate) is an essential cofactor for the glutathione peroxidase family of antioxidant enzymes, rounding out the formula's antioxidant support.

Advanced Ingredients, Superior Results

N-Acetyl-Cysteine, L-Glycine and Selenium each play a distinct, well-studied role in the body's antioxidant chemistry. Here's what's inside every capsule of CanPrev NAC+.

NAC (N-Acetyl-L-Cysteine)

A stable, acetylated form of the amino acid cysteine - the rate-limiting building block the body uses to synthesize glutathione, its main intracellular antioxidant.

600 mg

L-Glycine

A second glutathione-precursor amino acid, included alongside NAC to support the antioxidant tripeptide's synthesis.

70 mg

Selenium (Albion™ Selenium Glycinate)

An essential trace mineral and required cofactor for glutathione peroxidase, the enzyme family that carries out much of the body's antioxidant defense.

20 mcg

CanPrev NAC+ N-Acetyl-L-Cysteine: Supplement Facts

CanPrev™NAC+ N-Acetyl-L-Cysteine
English

Medicinal Ingredients (per capsule)

  • NAC (N-Acetyl-L-Cysteine) per capsule600 mg
  • L-Glycine per capsule70 mg
  • Selenium (Albion™ Selenium Glycinate) per capsule20 mcg

Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose.

Recommended Use or Purpose: Source of antioxidants that helps protect against oxidative stress.

Recommended Dose (Adults 19 years and older): Take 1 capsule daily with a meal, or as directed by a health care practitioner.

Cautions and Warnings: Do not use this product if you are taking antibiotics or nitroglycerin. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have kidney stones. Keep out of reach of children. Do not use if the safety seal is broken.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Made in Canada for CanPrev Natural Health Products Ltd., Brampton, ON, Canada. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Ingrédients médicinaux (par capsule)

  • NAC (N-acétylcystéine) par capsule600 mg
  • L-glycine par capsule70 mg
  • Sélénium (glycinate de sélénium Albion™) par capsule20 mcg

Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose, stéarate de magnésium, cellulose microcristalline.

Usage ou fins recommandés : Source d'antioxydants qui aide à protéger contre le stress oxydatif.

Posologie recommandée (adultes de 19 ans et plus) : Prendre 1 capsule par jour avec un repas, ou selon les directives d'un praticien de soins de santé.

Mises en garde et avertissements : Ne pas utiliser ce produit si vous prenez des antibiotiques ou de la nitroglycérine. Consulter un praticien de soins de santé avant l'usage si vous êtes enceinte ou allaitez, ou si vous avez des calculs rénaux. Tenir hors de portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.

NPN 80089237

600mg NAC + 70mg L-Glycine + 20mcg SeleniumVegan Capsules · Once-Daily Dose120 Capsules · 120-Day SupplyVegan · Non-GMO · Gluten-Free

Add CanPrev NAC+ to your daily routine

Get CanPrev NAC+ on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev NAC+

600mg NAC with L-Glycine and Selenium in one vegan capsule - premium CanPrev quality.

Three real actives, one capsule

600mg NAC, 70mg L-Glycine and 20mcg Selenium (Albion™ Selenium Glycinate) combined to support the body's antioxidant defenses - not NAC alone.

A glutathione-precursor pairing

NAC and L-Glycine are both amino-acid precursors the body uses to synthesize glutathione, while selenium is a required cofactor for the glutathione peroxidase antioxidant enzyme family.

Vegan, once-daily capsule

A single vegan capsule per day, easy to swallow, with no artificial colours, flavours or preservatives.

Trusted Canadian brand

CanPrev - a licensed Natural Health Product, NPN 80089237, made in Canada.

Inside every capsule

600mg of N-Acetyl-L-Cysteine (NAC), 70mg L-Glycine and 20mcg Selenium (Albion™ Selenium Glycinate) in one vegan capsule.

NAC (N-Acetyl-L-Cysteine) 600 mgL-Glycine 70 mgSelenium (Albion™ Selenium Glycinate) 20 mcg

How to use it

Take 1 capsule per day

Adults (19 years and older): take 1 capsule daily with a meal, or as directed by a health care practitioner.

Take with food

Take with a meal to support comfortable digestion.

Store safely

Keep out of reach of children. Do not use if the safety seal is broken.

Consult a practitioner if pregnant, breastfeeding, or with kidney stones

Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have kidney stones. Do not use if you are taking antibiotics or nitroglycerin.

What the research says about N-Acetyl-Cysteine, L-Glycine and Selenium

Educational summaries of published research on N-Acetyl-Cysteine, L-Glycine and Selenium generally - these are not product-specific claims. CanPrev NAC+'s own claim is the authorized use under NPN 80089237: it is a source of antioxidants that helps protect against oxidative stress.

NAC and Glutathione Synthesis - the Antioxidant Mechanism

A 2026 review maps NAC's antioxidant role across multiple organ systems

A narrative review describes N-acetylcysteine as a glutathione precursor and direct free-radical scavenger that modulates Nrf2 and NF-kB signalling, exhibiting antioxidant and anti-inflammatory effects across respiratory, cardiovascular, renal and neurological systems, with a generally favourable safety profile and mild gastrointestinal effects as the most common adverse events.

Review
Joy et al., La Clinica Terapeutica (2026)
NAC and Glutathione Synthesis - the Antioxidant Mechanism

Glutathione synthesis is rate-limited by the cysteine supplied through NAC

A review of glutathione and glutathione-dependent enzymes explains that glutamate cysteine ligase, the rate-limiting enzyme for glutathione synthesis, depends on adequate cysteine availability - the precursor amino acid that can be supplemented as N-acetylcysteine - and that glutathione levels decline with age.

Review
Lapenna, Ageing Research Reviews (2023)
NAC and Glutathione Synthesis - the Antioxidant Mechanism

NAC is one of two glutathione precursors reviewed for metabolic health

A 2026 review of dietary interventions for obesity and metabolic health highlights N-acetylcysteine and glycine as glutathione precursors, noting NAC shows promising benefits for insulin resistance, hepatic steatosis and cellular senescence, largely through antioxidant and anti-inflammatory mechanisms - though the authors note research in this area remains limited and mostly preclinical.

Review
Draganidis et al., Current Opinion in Clinical Nutrition and Metabolic Care (2026)
L-Glycine and NAC - the GlyNAC Precursor Pairing

Combined glycine and NAC supplementation corrected glutathione deficiency in older adults

A review of GlyNAC (glycine plus N-acetylcysteine) supplementation summarizes clinical and preclinical evidence that the combination corrects cellular glycine, cysteine and glutathione deficiencies, lowers oxidative stress, and improves mitochondrial function, inflammation, muscle strength, cognition and body composition in aging humans.

Review
Sekhar, The Journal of Nutrition (2021)
L-Glycine and NAC - the GlyNAC Precursor Pairing

Glycine and NAC are both reviewed as glutathione precursors for functional aging

A 2026 review of glycine and N-acetylcysteine supplementation in brain health and functional aging describes both as precursors of the antioxidant glutathione, with combined GlyNAC supplementation showing improvements in oxidative stress, mitochondrial dysfunction, inflammation, muscle strength and cognition across clinical and preclinical studies.

Review
Wang et al., Frontiers in Nutrition (2026)
L-Glycine and NAC - the GlyNAC Precursor Pairing

Glutathione and its precursors NAC and glycine are reviewed for type 2 diabetes

A review of glutathione's role in type 2 diabetes describes dietary supplementation with N-acetyl-cysteine and/or glycine, both glutathione precursors, as an area of study for improving oxidative-stress-related outcomes, while noting most existing research has focused on adult and elderly populations.

Review
Tuell et al., Antioxidants (2024)
Selenium and the Antioxidant Enzyme System

Selenium's health effects follow a U-shaped, status-dependent curve

A comprehensive review of selenium and human health describes selenoproteins' antioxidant and anti-inflammatory effects, noting that higher selenium status or supplementation benefits people with low selenium status, while people with already-adequate status may not see the same benefit - a status-dependent, U-shaped relationship.

Review
Rayman, The Lancet (2012)
Selenium and the Antioxidant Enzyme System

Selenium is required for thyroid protection against oxidative stress

A review of selenium's pathophysiological relevance explains that selenocysteine-containing selenoproteins protect the thyroid gland from hydrogen peroxide and reactive oxygen species generated during thyroid hormone synthesis, linking adequate selenium status to normal antioxidant enzyme function.

Review
Kohrle, Journal of Endocrinological Investigation (2013)
Selenium and the Antioxidant Enzyme System

Selenium status and antioxidant enzyme function are linked in kidney disease research

A review of selenium and kidney disease notes that selenium acts as a cofactor in selenoproteins involved in enzymatic antioxidant defense, that low selenium status is common in kidney disease patients, and that some studies report improved selenium status and immune function with oral or intravenous selenium supplementation.

Review
Iglesias et al., Journal of Nephrology (2012)
NAC in Human Trials - Oxidative Stress Biomarkers

A human trial found oral NAC reduced a urinary oxidative-stress biomarker

A randomized, double-blind, placebo-controlled trial gave adolescents with primary dysmenorrhea oral NAC (600mg twice daily for 5 days across three cycles) and found significantly lower urinary levels of the oxidative-stress marker 8-iso-prostaglandin F2-alpha compared with placebo, alongside reduced pain scores and less rescue NSAID use.

Human RCT
Al Khafaji et al., Georgian Medical News (2026)
NAC in Human Trials - Oxidative Stress Biomarkers

A glutathione-precursor supplement blend improved redox status in healthy adults

A randomized trial gave healthy adults an 8-week course of a glutathione-precursor dietary supplement and found significant increases in reduced glutathione and other reduced thiol species, alongside significantly increased endogenous levels of vitamins C, E and A, supporting a favourable shift in overall redox status.

Human RCT
Biswas et al., Nutrients (2020)
NAC in Human Trials - Oxidative Stress Biomarkers

An honest null result: NAC did not add cognitive benefit in a 24-week human trial

A randomized, double-blind, placebo-controlled trial gave patients with vascular mild cognitive impairment oral NAC (2400mg/day) for 24 weeks during cardiac rehabilitation and found NAC was well tolerated with adverse events comparable to placebo, but did not provide additional cognitive benefit beyond rehabilitation alone - an honest counterpoint showing oxidative-stress biomarker rationale does not always translate into a measurable functional outcome.

Human RCT (null result)
Gallagher et al., Alzheimer's Research & Therapy (2026)
NAC, the Liver and Detoxification Pathways - Educational, Not This Product's Claim

NAC is described as the most accepted treatment for drug-induced liver injury

A review of therapeutic strategies for liver disease describes N-acetylcysteine as a precursor to L-cysteine and glutathione, noting that due to its antioxidant and anti-inflammatory actions, NAC is the most accepted treatment for drug-induced liver injury (particularly after acetaminophen overdose) and has also been used for chronic liver injuries including hepatosteatosis and fibrosis.

Review
Muriel et al., International Journal of Molecular Sciences (2026)
NAC, the Liver and Detoxification Pathways - Educational, Not This Product's Claim

Novel NAC-derived compounds outperformed conventional NAC in a mouse liver-injury model

A 2026 mouse study found that supersulfide donors derived from N-acetylcysteine attenuated acetaminophen-induced liver injury more effectively than conventional NAC in this animal model, by enhancing detoxification of the reactive toxic metabolite and suppressing inflammation.

Animal study
Guo et al., Redox Biology (2026)
NAC, the Liver and Detoxification Pathways - Educational, Not This Product's Claim

The classic 1985 mouse study establishing NAC's liver-protective mechanism

A foundational mouse study found that N-acetylcysteine (1200mg/kg) prevented hepatic damage caused by a toxic acetaminophen dose, helping establish the detoxification mechanism that later made NAC the standard antidote for acetaminophen overdose.

Animal study
Corcoran et al., Journal of Pharmacology and Experimental Therapeutics (1985)
NAC, Immune Function and Respiratory Research - Educational, Not This Product's Claim

An expert consensus reviewed NAC's antioxidant and immunomodulatory role in respiratory disease

A 2026 evidence-based consensus document from a panel of pulmonologists reviewed NAC's antioxidant, anti-inflammatory, immunomodulatory and anti-biofilm effects across eight respiratory conditions, concluding NAC is a useful adjunct in several chronic respiratory conditions and was consistently rated safe and well tolerated across the reviewed studies.

Expert consensus review
Barne et al., Frontiers in Medicine (2026)
NAC, Immune Function and Respiratory Research - Educational, Not This Product's Claim

A review examined antioxidants including NAC for immune-modulating effects in COVID-19 pneumonia

A review of antioxidants in COVID-19 pneumonia describes N-acetylcysteine among several antioxidants studied for reactive-oxygen-species-scavenging properties that may support immune cell function and reduce inflammation, while noting further research combining literature review with real-world data is needed to establish evidence-based guidelines.

Review
Sanduzzi Zamparelli et al., Life (2025)
NAC, Immune Function and Respiratory Research - Educational, Not This Product's Claim

A pediatric trial combining NAC with a mucolytic improved immune and lung-function markers

A randomized trial in children with pneumonia found NAC combined with ambroxol hydrochloride was associated with improved immunoglobulin levels (IgA, IgG, IgM, C3) and better lung-function parameters compared with ambroxol alone, with no significant difference in the rate of adverse reactions between groups.

Human RCT
Xue et al., Clinics (2024)
Selenium, Immune Function and Thyroid Health - Educational

Selenium supplementation changed cytokine production in women with Hashimoto's thyroiditis

A 6-month trial gave women with newly diagnosed Hashimoto's thyroiditis 100mcg of selenium daily and found significant changes in the production of two cytokines (interferon-gamma decreased, interleukin-1-beta increased), illustrating selenium's measurable effect on immune cell signalling in this population.

Human trial
Kryczyk-Koziol et al., Nutrients (2022)
Selenium, Immune Function and Thyroid Health - Educational

Selenomethionine reduced thyroid antibody titers in a controlled human trial

A prospective case-control study gave women with Hashimoto's thyroiditis 200mcg of selenomethionine daily for 6 months and found significant reductions in both thyroid peroxidase and thyroglobulin antibody titers, with the effect more pronounced in a subgroup also taking a statin.

Human trial
Krysiak et al., Current Medical Research and Opinion (2018)
Selenium, Immune Function and Thyroid Health - Educational

An honest counterpoint: selenium normalized status but antibody titers rose in one cohort

A retrospective clinical study of selenium-deficient Hashimoto's thyroiditis patients found that 6 months of selenium supplementation restored normal serum selenium levels, but antibody titers unexpectedly increased rather than decreased - contrasting with several other trials reporting antibody reduction, and underscoring that selenium's effect on thyroid autoimmunity is not uniform across all populations or study designs.

Human study
Acik and Aydin, Endocrine, Metabolic & Immune Disorders Drug Targets (2026)
NAC and Selenium Safety and Tolerability - Educational, General Ingredient Research

A phase 1 human trial found oral NAC well tolerated up to 1800mg twice daily

A phase 1 trial gave adults with retinitis pigmentosa oral NAC at 600mg, 1200mg or 1800mg twice daily (increasing to three times daily) over 24 weeks and found it was safe and well tolerated overall, with 9 drug-related gastrointestinal adverse events that resolved spontaneously or with dose reduction - notably higher doses than this product's labelled 600mg once-daily use.

Human trial
Campochiaro et al., Journal of Clinical Investigation (2020)
NAC and Selenium Safety and Tolerability - Educational, General Ingredient Research

A review found no evidence of selenium toxicity even well above the tolerable upper intake level

A review of selenium-yeast supplementation studies found that of about a dozen human intervention trials, none showed evidence of toxicity even at intakes up to 800mcg per day over a period of years - well above the (300mcg/day) tolerable upper intake level referenced in the review, though supplementation above one's needs is not advised.

Review
Rayman, British Journal of Nutrition (2004)
NAC and Selenium Safety and Tolerability - Educational, General Ingredient Research

Honest context: much higher-dose IV NAC regimens carry more frequent gastrointestinal effects

A clinical trial comparing a shorter versus standard high-dose intravenous NAC antidote regimen for paracetamol overdose found gastrointestinal adverse effects in the majority of patients in both groups (73% short regimen vs 65% standard) - a different route and much higher dose than this product's 600mg oral once-daily capsule, illustrating that NAC's tolerability profile is dose- and route-dependent.

Human RCT
Isbister et al., Journal of Hepatology (2025)

Frequently asked questions

What is CanPrev NAC+ and what does it do?

It's a vegan capsule supplement providing 600mg of N-Acetyl-L-Cysteine (NAC), 70mg of L-Glycine and 20mcg of Selenium per capsule. Its Health Canada-authorized use is that it is a source of antioxidants that helps protect against oxidative stress.

How do I take it?

Adults (19 years and older): take 1 capsule daily with a meal, or as directed by a health care practitioner. Each 120-capsule bottle is a 120-day supply at this dose.

Why does this formula include L-Glycine and Selenium along with NAC?

NAC and L-Glycine are both amino-acid precursors the body uses to synthesize glutathione, its main intracellular antioxidant, while selenium is an essential cofactor for the glutathione peroxidase enzyme family that carries out much of the body's antioxidant defense - the three actives are combined to support this shared antioxidant pathway.

What is NAC?

N-Acetyl-L-Cysteine (NAC) is a stable, acetylated form of the amino acid cysteine, and cysteine is the rate-limiting building block the body uses to make glutathione.

Is it vegan and allergen-friendly?

Yes - the capsules are vegan (a hypromellose shell), non-GMO, and free from gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours and preservatives.

Who should not use it?

Do not use if you are taking antibiotics or nitroglycerin. Consult a health care practitioner before use if you are pregnant or breastfeeding, or if you have kidney stones. Do not use if the safety seal is broken. Keep out of reach of children.

How long does one bottle last?

Each bottle contains 120 vegan capsules - a 120-day supply at the labelled adult dose of 1 capsule per day.

Where is it made?

CanPrev NAC+ is made in Canada for CanPrev Natural Health Products Ltd. (Brampton, ON), and is a licensed Natural Health Product under NPN 80089237.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

600mg NAC + 70mg L-Glycine + 20mcg SeleniumVegan Capsules · Once-Daily Dose120 Capsules · 120-Day SupplyVegan · Non-GMO · Gluten-Free

Add CanPrev NAC+ to your daily routine

Get CanPrev NAC+ on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80089237. Source of antioxidants that helps protect against oxidative stress. The research summaries below concern N-Acetyl-Cysteine (NAC), L-Glycine and Selenium generally, and are educational - they are not claims about this finished product. Do not use if you are taking antibiotics or nitroglycerin. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have kidney stones. Do not use if the safety seal is broken. Keep out of reach of children. Read and follow the label. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use this product if you are taking antibiotics or nitroglycerin. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have kidney stones. Keep out of reach of children. Do not use if the safety seal is broken.

Indications

Recommended Use or Purpose: Source of antioxidants that helps protect against oxidative stress.

Ingredients

Medicinal Ingredients (per capsule): NAC (N-Acetyl-L-Cysteine) 600 mg, L-Glycine 70 mg, Selenium (Albion™ Selenium Glycinate) 20 mcg. Non-medicinal ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults 19 years and older): Take 1 capsule daily with a meal, or as directed by a health care practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Made in Canada for CanPrev Natural Health Products Ltd., Brampton, ON, Canada. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.