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Health Canada NPN 80129458 490 mg Full-Spectrum 7-Mushroom Blend (Fruiting Body + Mycelium), 1-2x daily Vegan / Organically Sourced / Non-GMO / Gluten-Free Formulated & Made in Canada
Multi-Mushroom Full SpectrumMulti-Mushroom Full Spectrum - benefits and key ingredients Multi-Mushroom Full Spectrum - lifestyleMulti-Mushroom Full Spectrum - ingredientsMulti-Mushroom Full Spectrum - supplement facts panel

CanPrev Multi-Mushroom Full Spectrum - 7 Mushrooms | 60 Vegan Caps

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$30.99 CAD ($0.52 / capsule)
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BrandCanPrev
Serving1 capsule, 1 to 2 times daily with food (490 mg full-spectrum 7-mushroom blend per capsule)
Licensed Natural Health ProductNPN 80129458
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • 490 MG FULL-SPECTRUM 7-MUSHROOM BLEND: Each vegetable capsule combines Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail - 50 mg fruiting-body extract from each species (8:1, or 4:1 for Maitake) plus 20 mg of that species' cultured mycelium - the full spectrum of all 7 mushrooms in one capsule.
  • SOURCE OF FUNGAL POLYSACCHARIDES WITH IMMUNOMODULATING PROPERTIES: The first recommended use authorized on this product's Health Canada licence (NPN 80129458).
  • PROVIDES ANTIOXIDANTS THAT HELP PROTECT AGAINST FREE RADICALS: The second recommended use authorized on this same Health Canada licence.
  • FOCUS & COGNITIVE CLARITY SUPPORT: Lion's Mane is traditionally used, and widely researched, for supporting mental clarity and focus, alongside Chaga and Cordyceps for everyday vitality.
  • DAILY WELLNESS & IMMUNE SUPPORT: Reishi, Turkey Tail, Shiitake and Maitake are among the most-studied traditional mushrooms for immune-system-related research.
  • FRUITING BODY + CULTURED MYCELIUM, FOR EVERY SPECIES: Unlike blends built from a single mushroom part, this formula pairs an organically sourced fruiting-body extract with cultured mycelium for all 7 species.
  • ORGANICALLY SOURCED, VEGAN FORMULA: Organically grown mushrooms in a vegan vegetable capsule - non-GMO, gluten-free, with no artificial colours, flavours or preservatives.
  • MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed under NPN 80129458.

Product Description

Multi-Mushroom Full Spectrum - 7 Medicinal Mushrooms, Fruiting Body + Mycelium

CanPrev Multi-Mushroom Full Spectrum

490 mg of full-spectrum mushroom blend in every vegetable capsule: Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail, each contributing a 50 mg fruiting-body extract (8:1, or 4:1 for Maitake) plus 20 mg of that same species' cultured mycelium - the full spectrum of all 7 mushrooms, taken 1 to 2 times a day with food. A source of fungal polysaccharides with immunomodulating properties, and a source of antioxidants that help protect against free radicals. Organically sourced, vegan, and licensed as a Natural Health Product. Licensed Natural Health Product NPN 80129458.

490 mg de mélange de champignons à spectre complet dans chaque capsule végétale : Chaga, Cordyceps militaris, Hydne hérisson (Lion's Mane), Maitake, Reishi, Shiitaké et Queue de dinde, chacun apportant un extrait de corps fructifère de 50 mg (8:1, ou 4:1 pour le Maitake) ainsi que 20 mg de mycélium cultivé de la même espèce - le spectre complet des 7 champignons, à prendre une à deux fois par jour avec de la nourriture. Source de polysaccharides fongiques ayant des propriétés immunomodulatrices, et source d'antioxydants qui aident à protéger contre les radicaux libres. Source biologique, végétalien, et homologué comme produit de santé naturel.

Multi-Mushroom Full Spectrum lifestyle
CanPrev Multi-Mushroom Full Spectrum
490 mg Full-Spectrum 7-Mushroom Blend · Fruiting Body + Mycelium

One Capsule, Seven Mushrooms, the Full Spectrum

50 mg fruiting-body extract + 20 mg cultured mycelium from each of 7 species, 1-2 capsules daily

490 mg of Full-Spectrum 7-Mushroom Blend, 1-2x Daily

Each vegetable capsule delivers 350 mg of combined fruiting-body extract (50 mg each from Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail) plus 140 mg of combined cultured mycelium (20 mg from each species) - 490 mg total, taken 1 to 2 times a day with food.

Fruiting Body + Cultured Mycelium - for Every Species

Most multi-mushroom blends use only one part of each fungus. This formula pairs an organically sourced fruiting-body extract with cultured mycelium for all 7 species, for a broader compound profile than a single-source extract.

What the Research Explores About These 7 Mushrooms

Educational summaries of published research on the individual species in this blend (Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake, Turkey Tail) - CanPrev Multi-Mushroom Full Spectrum's own label claims are the two uses authorized under NPN 80129458: a source of fungal polysaccharides with immunomodulating properties, and a source of antioxidants that help protect against free radicals.

Chaga (Inonotus obliquus)

Organically sourced Chaga fruiting body, extracted with hot water and alcohol, paired with cultured Chaga mycelium for the full spectrum of compounds.

50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Chaga

Cordyceps militaris

Organically sourced Cordyceps militaris fruiting body paired with cultured Ophiocordyceps sinensis mycelium (stroma) for a broader compound profile.

50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium (stroma, Ophiocordyceps sinensis) = 70 mg full-spectrum Cordyceps

Lion's Mane (Hericium erinaceus)

Organically sourced Lion's Mane fruiting body extract combined with cultured Hericium erinaceus mycelium.

50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Lion's Mane

Maitake (Grifola frondosa)

Organically sourced Maitake fruiting body extract combined with cultured Grifola frondosa mycelium.

50 mg fruiting body 4:1 extract (equiv. 200 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Maitake

Reishi (Ganoderma lucidum)

Organically sourced Reishi fruiting body extract combined with cultured Ganoderma lucidum mycelium.

50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Reishi

Shiitake (Lentinula edodes)

Organically sourced Shiitake fruiting body extract combined with cultured Lentinula edodes mycelium.

50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Shiitake

Turkey Tail (Trametes versicolor)

Organically sourced Turkey Tail fruiting body extract combined with cultured Trametes versicolor mycelium.

50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Turkey Tail

CanPrev Multi-Mushroom Full Spectrum: Supplement Facts

CanPrev™Multi-Mushroom Full Spectrum
English

Each vegetable capsule contains:

  • Chaga (fruiting body, Inonotus obliquus) 8:1 extract equivalent to 400 mg dry fruiting body Hot water and alcohol extract50 mg
  • Cordyceps militaris (fruiting body) 8:1 extract equivalent to 400 mg dry fruiting body Hot water and alcohol extract50 mg
  • Lion's Mane (fruiting body, Hericium erinaceus) 8:1 extract equivalent to 400 mg dry fruiting body Hot water and alcohol extract50 mg
  • Maitake (fruiting body, Grifola frondosa) 4:1 extract equivalent to 200 mg dry fruiting body Hot water extract50 mg
  • Reishi (fruiting body, Ganoderma lucidum) 8:1 extract equivalent to 400 mg dry fruiting body Hot water and alcohol extract50 mg
  • Shiitake (fruiting body, Lentinula edodes) 8:1 extract equivalent to 400 mg dry fruiting body Hot water extract50 mg
  • Turkey Tail (fruiting body, Trametes versicolor) 8:1 extract equivalent to 400 mg dry fruiting body Hot water extract50 mg
  • Chaga (cultured mycelia, Inonotus obliquus)20 mg
  • Cordyceps (stroma, Ophiocordyceps sinensis)20 mg
  • Lion's Mane (cultured mycelia, Hericium erinaceus)20 mg
  • Maitake (cultured mycelia, Grifola frondosa)20 mg
  • Reishi (cultured mycelia, Ganoderma lucidum)20 mg
  • Shiitake (cultured mycelia, Lentinula edodes)20 mg
  • Turkey Tail (cultured mycelia, Trametes versicolor)20 mg

Non-Medicinal Ingredients: Acacia gum, hypromellose, magnesium stearate.

Recommended Use or Purpose: Source of fungal polysaccharides with immunomodulating properties. Provides antioxidants that help protect against free radicals.

Recommended Dose (Adults 18 years and older): Take 1 capsule, 1 to 2 times per day, with food. Recommended Duration of Use: No specific duration restriction is stated on this product's Health Canada licence; as with any natural health product, consult a health care practitioner about use beyond a few months.

Cautions and Warnings: Consult a health care practitioner prior to use if you are taking blood thinners (anticoagulant or antiplatelet medication), if you have diabetes or take blood-sugar-lowering medication, or if you are pregnant or breastfeeding. Discontinue use and consult a health care practitioner if you experience a hypersensitivity or allergic reaction. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

Français

Chaque capsule végétale contient :

  • Chaga (corps fructifère, Inonotus obliquus) extrait 8:1 équivalent à 400 mg de corps fructifère sec Extrait à l'alcool et à l'eau chaude50 mg
  • Cordyceps militaris (corps fructifère) extrait 8:1 équivalent à 400 mg de corps fructifère sec Extrait à l'alcool et à l'eau chaude50 mg
  • Hydne hérisson (corps fructifère, Hericium erinaceus) extrait 8:1 équivalent à 400 mg de corps fructifère sec Extrait à l'alcool et à l'eau chaude50 mg
  • Maitake (corps fructifère, Grifola frondosa) extrait 4:1 équivalent à 200 mg de corps fructifère sec Extrait à l'eau chaude50 mg
  • Reishi (corps fructifère, Ganoderma lucidum) extrait 8:1 équivalent à 400 mg de corps fructifère sec Extrait à l'alcool et à l'eau chaude50 mg
  • Shiitaké (corps fructifère, Lentinula edodes) extrait 8:1 équivalent à 400 mg de corps fructifère sec Extrait à l'eau chaude50 mg
  • Queue de dinde (corps fructifère, Trametes versicolor) extrait 8:1 équivalent à 400 mg de corps fructifère sec Extrait à l'eau chaude50 mg
  • Chaga (mycélium cultivé, Inonotus obliquus)20 mg
  • Cordyceps (stroma, Ophiocordyceps sinensis)20 mg
  • Hydne hérisson (mycélium cultivé, Hericium erinaceus)20 mg
  • Maitake (mycélium cultivé, Grifola frondosa)20 mg
  • Reishi (mycélium cultivé, Ganoderma lucidum)20 mg
  • Shiitaké (mycélium cultivé, Lentinula edodes)20 mg
  • Queue de dinde (mycélium cultivé, Trametes versicolor)20 mg

Ingrédients non médicinaux : Gomme d'acacia, hypromellose, stéarate de magnésium.

Usage ou fins recommandés : Source de polysaccharides fongiques ayant des propriétés immunomodulatrices. Fournit des antioxydants qui aident à protéger contre les radicaux libres.

Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule, 1 à 2 fois par jour, avec de la nourriture. Durée d'utilisation recommandée : aucune restriction de durée particulière n'est indiquée pour ce produit en vertu de sa licence de Santé Canada; comme pour tout produit de santé naturel, consultez un praticien de soins de santé pour un usage prolongé au-delà de quelques mois.

Mises en garde : Consultez un praticien de soins de santé avant l'usage si vous prenez des anticoagulants ou des antiplaquettaires, si vous êtes diabétique ou prenez des médicaments hypoglycémiants, ou si vous êtes enceinte ou si vous allaitez. Cessez l'utilisation et consultez un praticien de soins de santé en cas de réaction d'hypersensibilité ou allergique. Garder hors de la portée des enfants.

NPN 80129458

490 mg Full-Spectrum 7-Mushroom Blend, 1-2x daily60 capsules · up to 2-month supplyVegan · Organically Sourced · Non-GMO · Gluten-FreeMade in Canada

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Why CanPrev Multi-Mushroom Full Spectrum

A full-spectrum 490 mg blend of 7 medicinal mushrooms - organically sourced fruiting-body extract plus cultured mycelium for every species - in one vegan capsule, 1 to 2 times daily.

490 mg Full-Spectrum 7-Mushroom Blend

Combines Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail - 50 mg fruiting-body extract plus 20 mg cultured mycelium from each species - the full spectrum of all 7 mushrooms in a single daily capsule.

Licensed source of immunomodulating polysaccharides and antioxidants

A Health Canada-licensed source of fungal polysaccharides with immunomodulating properties, and of antioxidants that help protect against free radicals (NPN 80129458).

Organically sourced, vegan simplicity

Organically grown mushrooms in a vegan vegetable capsule - non-GMO, gluten-free, with no artificial colours, flavours or preservatives.

Trusted Canadian brand

CanPrev - formulated and made in Canada, licensed under NPN 80129458.

Inside every capsule

490 mg of full-spectrum 7-mushroom blend - Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail, each as a 50 mg fruiting-body extract (8:1, or 4:1 for Maitake) plus 20 mg of that same species' cultured mycelium - 1 to 2 capsules a day, with food.

Chaga (Inonotus obliquus) 50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum ChagaCordyceps militaris 50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium (stroma, Ophiocordyceps sinensis) = 70 mg full-spectrum CordycepsLion's Mane (Hericium erinaceus) 50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Lion's ManeMaitake (Grifola frondosa) 50 mg fruiting body 4:1 extract (equiv. 200 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum MaitakeReishi (Ganoderma lucidum) 50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum ReishiShiitake (Lentinula edodes) 50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum ShiitakeTurkey Tail (Trametes versicolor) 50 mg fruiting body 8:1 extract (equiv. 400 mg dry) + 20 mg cultured mycelium = 70 mg full-spectrum Turkey Tail

How to use it

Take 1 capsule, 1 to 2 times per day

Adults 18 years and older: take one vegetable capsule, once or twice daily with food, or as directed by a qualified health care practitioner.

With food, to help avoid digestive upset

Taking this full-spectrum 7-mushroom blend alongside a meal is recommended to help avoid digestive upset.

A bottle lasts 1 to 2 months

60 capsules provide a 1-month supply at 2 capsules a day, or up to a 2-month supply at 1 capsule a day.

What the research says about these 7 medicinal mushrooms

Educational summaries of published research on the individual species in this blend (Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake, Turkey Tail) and on medicinal mushroom polysaccharides generally; not product-specific claims. CanPrev Multi-Mushroom Full Spectrum's own label claims are the two uses authorized under NPN 80129458: a source of fungal polysaccharides with immunomodulating properties, and a source of antioxidants that help protect against free radicals.

Multi-Mushroom Polysaccharides & Immune Modulation

A 2026 review maps how mushroom compounds activate innate and adaptive immunity

A review of mushroom-derived immunomodulators found that polysaccharides, fungal immunomodulatory proteins, lectins, terpenoids and phenolics interact with pattern-recognition receptors on macrophages, dendritic cells and natural killer cells, triggering signaling cascades that regulate cytokine production, Th1/Th2 balance and regulatory T-cell function.

Review
Zhang, Lau & Kue, International Immunopharmacology (2026)
Multi-Mushroom Polysaccharides & Immune Modulation

A 2026 review found mushroom polysaccharides work mainly by stimulating immunity rather than attacking tumours directly

Reviewing dietary and medicinal mushrooms in oncology, researchers found their cell-wall polysaccharides and proteoglycans are recognized by intestinal immune cells, enhancing antitumour immunity primarily through indirect immune modulation; separately, mushroom-derived substances were reported to help mitigate chemotherapy and radiotherapy side effects and support immune function and quality of life in cancer patients.

Review
Kirdeeva, Fefilova, Karpova et al., International Journal of Molecular Sciences (2026)
Multi-Mushroom Polysaccharides & Immune Modulation

A 2026 review found mushroom beta-glucans are fermented by gut bacteria into compounds that support immune regulation

A narrative review found mushroom-derived polysaccharides - particularly beta-glucans, along with polyphenols and chitin - resist digestion and are fermented by gut microorganisms into short-chain fatty acids that help maintain intestinal barrier integrity, immune regulation and metabolic homeostasis, though the authors noted well-designed human clinical trials remain limited.

Review
Mattioli, Camarda, Aicardi et al., Foods (2026)
Antioxidant & Free-Radical Protection

A review found mushrooms are the richest dietary source of the antioxidant compound ergothioneine

Reviewing preclinical evidence, researchers found ergothioneine - an antioxidant amino-acid derivative for which edible mushrooms are the most abundant dietary source - preferentially accumulates in tissues exposed to oxidative stress, and proposed a potential role in supporting cardiometabolic health, though the authors noted no well-defined human clinical trials had yet confirmed this.

Review
Lam-Sidun, Peters & Borradaile, International Journal of Molecular Sciences (2021)
Antioxidant & Free-Radical Protection

A 2026 review found the mushroom antioxidant ergothioneine crosses the blood-brain barrier and counters oxidative stress

Reviewing ergothioneine - a thiol compound abundant in mushrooms with a long half-life and high bioavailability - researchers found it reduces oxidative stress, mitochondrial dysfunction, protein aggregation and neuroinflammation across multiple preclinical models, and summarized early clinical trials testing its safety and potential efficacy.

Review
Tng, Cheah, Halliwell & Lim, Antioxidants (2026)
Antioxidant & Free-Radical Protection

A review found mushroom and other dietary polysaccharides show antioxidant activity alongside blood-sugar benefits

Summarizing evidence on dietary polysaccharides - including those from edible mushrooms - researchers found they show hypoglycemic, antioxidant and anti-inflammatory effects in laboratory and animal research, working partly by enhancing insulin signaling pathways and easing oxidative stress.

Review
Ganesan & Xu, Molecules (2019)
Reishi (Ganoderma lucidum)

A 12-week trial found Reishi beta-glucans raised immune cell counts in children

In a randomized, double-blind, placebo-controlled trial in children aged 3-5 in Medellín, Colombia, 12 weeks of a yogurt fortified with Ganoderma lucidum (Reishi) beta-glucans significantly increased circulating CD3+, CD4+ and CD8+ T-lymphocyte counts compared to placebo, with no adverse safety signals.

Human RCT
Henao, Urrego, Cano & Higuita, International Journal of Medicinal Mushrooms (2018)
Reishi (Ganoderma lucidum)

A crossover trial found Reishi improved insulin sensitivity in adults with borderline high blood pressure or cholesterol

In a randomized, double-blind, placebo-controlled crossover trial of 26 adults with borderline hypertension or hyperlipidaemia, 12 weeks of Ganoderma lucidum (Lingzhi/Reishi) lowered plasma insulin and insulin resistance (HOMA-IR) compared to placebo, though carry-over effects limited full analysis of its effect on triglycerides and HDL cholesterol.

Human RCT (crossover)
Chu, Benzie, Lam et al., British Journal of Nutrition (2011)
Reishi (Ganoderma lucidum)

A Cochrane review found Reishi alongside chemotherapy improved tumour response and immune markers

Pooling 5 randomized controlled trials, a Cochrane systematic review found Ganoderma lucidum (Reishi) given alongside chemotherapy or radiotherapy was associated with a higher tumour response rate than treatment alone, along with increased CD3+, CD4+ and CD8+ T-cell percentages and improved quality-of-life scores - though the reviewers found insufficient evidence to support Reishi as a first-line cancer treatment on its own.

Systematic review (Cochrane)
Jin, Ruiz Beguerie, Sze & Chan, Cochrane Database of Systematic Reviews (2016)
Turkey Tail (Trametes versicolor)

A phase I human trial found Turkey Tail was well tolerated and raised immune cell markers in breast cancer patients

In a phase I dose-escalation trial, 9 women who had recently completed radiotherapy for breast cancer took daily Trametes versicolor (Turkey Tail) for 6 weeks at doses up to 9 grams/day; the preparation was well tolerated and associated with dose-related increases in lymphocyte counts, natural killer cell activity, and CD8+ T cells and CD19+ B cells.

Human trial (Phase I)
Torkelson, Sweet, Martzen et al., ISRN Oncology (2012)
Turkey Tail (Trametes versicolor)

A randomized trial found a Turkey Tail extract acted as a prebiotic in healthy adults

In a randomized clinical trial of 24 healthy volunteers, polysaccharopeptide from Trametes versicolor (Turkey Tail) produced consistent, favourable shifts in gut microbiome composition over 8 weeks - in clear contrast to the antibiotic amoxicillin, which disrupted the microbiome for weeks after treatment ended - supporting its activity as a dietary prebiotic.

Human RCT
Pallav, Dowd, Villafuerte et al., Gut Microbes (2014)
Turkey Tail (Trametes versicolor)

A 28-day safety study found no toxicity from an extracellular Turkey Tail polysaccharopeptide in mice

Oral administration of an extracellular polysaccharopeptide from a Trametes versicolor (Turkey Tail) strain for 28 days produced no adverse clinical signs, organ-weight changes or abnormal blood/urine findings in mice at doses up to 1000 mg/kg/day, supporting its safety profile as a food or dietary-supplement ingredient.

Animal study
Lai, Teng, Hsu et al., International Journal of Medicinal Mushrooms (2011)
Chaga (Inonotus obliquus)

Chaga polyphenols showed antioxidant and anti-inflammatory activity in a gout-model study

Testing three key polyphenols isolated from Inonotus obliquus (Chaga), researchers found they inhibited xanthine oxidase (the enzyme that generates uric acid) and scavenged free radicals, while the whole Chaga extract reduced reactive oxygen species, nitric oxide and inflammatory cytokines (TNF-alpha, IL-1beta) and downregulated the TLR4/MyD88/NF-kB inflammatory signaling pathway in a monosodium-urate-stimulated macrophage model.

In vitro study
Shu, Chen, Pang et al., Antioxidants (2026)
Chaga (Inonotus obliquus)

A Chaga compound eased inflammation-linked cognitive impairment in mice

Researchers isolated eight compounds from Inonotus obliquus (Chaga) and found one triterpenoid significantly reduced inflammatory markers in microglial brain-immune cells; in a scopolamine-induced memory-impairment mouse model, the same compound meaningfully improved behavioural measures of cognitive function and raised expression of the neurotrophic factors NGF and BDNF.

Animal / in vitro study
Kou, Bai, Yang et al., Fitoterapia (2025)
Chaga (Inonotus obliquus)

A Chaga extract eased atopic-dermatitis-like skin inflammation in mice via antioxidant activity

In mice sensitized to develop atopic dermatitis, a topical ethanol-extracted Chaga mushroom by-product significantly improved dermatitis severity scores, reduced mast-cell infiltration and IgE levels, and lowered oxidative-stress and inflammatory cytokine markers in the skin, attributed to the extract's antioxidant and immunomodulatory activity.

Animal study
Liu, Zhang, Yang et al., Journal of Microbiology and Biotechnology (2026)
Shiitake (Lentinula edodes)

A randomized trial found a Shiitake beta-glucan extract modulated gut microbiota linked to cholesterol metabolism

In a randomized, double-blind, placebo-controlled trial of 52 adults with untreated mild hypercholesterolemia, 8 weeks of a beta-D-glucan-enriched extract from Lentinula edodes (Shiitake) was safe and well tolerated, and modulated colonic gut microbiota differently than placebo, with several bacterial genera correlating with cholesterol-related biomarkers - though it did not significantly change cholesterol levels directly in this trial.

Human RCT
Morales, Shetty, López-Plaza et al., European Journal of Nutrition (2021)
Shiitake (Lentinula edodes)

A randomized trial found Shiitake bars lowered triglycerides and boosted antioxidant markers

In a randomized, double-blind, placebo-controlled trial of 68 people with borderline high cholesterol, 66 days of Lentinula edodes (Shiitake) nutrition bars significantly reduced triglycerides by 10% and increased reduced glutathione (the body's main endogenous antioxidant) while lowering lipid peroxidation, versus placebo.

Human RCT
Spim, Pistila, Pickler et al., International Journal of Medicinal Mushrooms (2021)
Shiitake (Lentinula edodes)

Shiitake beta-1,6-glucans boosted immune cell activity and gut microbiota diversity in mice

A newly isolated, high-yield beta-1,6-glucan fraction from Lentinula edodes (Shiitake) significantly promoted the proliferation of splenic T lymphocytes and phagocytic activity of macrophages in mice, while increasing gut microbiota diversity and short-chain-fatty-acid-producing bacteria - with the immune benefit found to depend on the gut microbiota.

Animal study
Qu, Ji, Long et al., Food Chemistry (2024)
Maitake (Grifola frondosa)

A human study found Maitake D-Fraction raised natural killer cell activity in cancer patients

Administering Maitake (Grifola frondosa) D-Fraction to cancer patients without concurrent chemotherapy, researchers found natural killer cell cytotoxic activity increased in all patients examined, alongside reduced tumour marker expression and hindered metastatic progression - though this was an open, uncontrolled clinical observation rather than a blinded trial.

Human clinical study
Kodama, Komuta & Nanba, Journal of Medicinal Food (2003)
Maitake (Grifola frondosa)

Maitake D-Fraction activated both innate and adaptive immunity in healthy mice

Daily Maitake (Grifola frondosa) D-Fraction given to healthy mice for 17 days activated macrophages and dendritic cells (raising nitric oxide and interleukin-12 production) and increased interferon-gamma, suggesting the polysaccharide can stimulate immune defenses even in the absence of disease.

Animal study
Kodama, Murata & Nanba, Journal of Medicinal Food (2004)
Maitake (Grifola frondosa)

Maitake D-Fraction combined with a TLR9 agonist drove tumour regression through dendritic-cell immunity in mice

Combining Maitake (Grifola frondosa) D-Fraction with a Toll-like-receptor-9 agonist synergistically matured dendritic cells and boosted interleukin-12 production in a mouse tumour model, generating a strong antigen-specific immune response that included increased tumour-infiltrating dendritic cells and interferon-gamma-producing T cells, and was associated with tumour regression.

Animal study
Masuda, Nawa, Nakayama, Konishi & Nanba, Journal of Leukocyte Biology (2015)
Lion's Mane (Hericium erinaceus)

A 16-week trial found Lion's Mane improved cognitive scores in adults with mild cognitive impairment

In a double-blind, placebo-controlled trial of Japanese men and women aged 50-80 with mild cognitive impairment, 16 weeks of Hericium erinaceus (Lion's Mane, Yamabushitake) tablets significantly increased scores on a cognitive function scale compared to placebo, with scores rising over the treatment period and declining again after supplementation stopped - with no adverse effects observed in lab testing.

Human RCT
Mori, Inatomi, Ouchi, Azumi & Tuchida, Phytotherapy Research (2009)
Lion's Mane (Hericium erinaceus)

A single dose of Lion's Mane improved working memory and reaction time in a crossover trial

In a randomized, double-blind, placebo-controlled crossover trial, a single 1 g dose of Nordic-grown Lion's Mane extract significantly improved performance on a Serial 7s attention task and reaction time on an N-Back working-memory task compared to placebo, with benefits most evident 2 hours after intake.

Human RCT
La Monica, Raub, Ziegenfuss et al., Nutrients (2023)
Lion's Mane (Hericium erinaceus)

A pilot trial found Lion's Mane sped up cognitive-task performance and trended toward lower stress

A double-blind, placebo-controlled, parallel-groups pilot study in 41 healthy young adults found a single 1.8 g dose of Lion's Mane significantly sped up performance on the Stroop cognitive task 60 minutes after intake, with a non-significant trend toward reduced subjective stress after 28 days of daily use - the small sample size means the findings should be interpreted cautiously.

Human RCT (pilot)
Docherty, Doughty & Smith, Nutrients (2023)

Frequently asked questions

How do I take CanPrev Multi-Mushroom Full Spectrum?

Adults 18 years and older take 1 capsule, 1 to 2 times per day, with food, or as directed by a qualified health care practitioner.

What's in each capsule?

Each capsule contains 7 medicinal mushrooms - Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail - each contributing 50 mg of an 8:1 (4:1 for Maitake) fruiting-body extract plus 20 mg of that species' cultured mycelium, for 490 mg of full-spectrum blend in total. Non-medicinal ingredients are acacia gum, hypromellose and magnesium stearate.

What does 'Full Spectrum' mean on this label?

It means each of the 7 mushroom species is represented by both its fruiting body (as a concentrated extract) and its cultured mycelium - two sources per species combined for a broader compound profile than a single-source extract.

What is the licensed use of this product?

This product's Health Canada licence (NPN 80129458) authorizes two uses: as a source of fungal polysaccharides with immunomodulating properties, and as a source of antioxidants that help protect against free radicals. Broader research on the individual mushroom species (cognitive focus, energy, immune support, and more) is educational and not an additional label claim for this specific product.

Can I take this if I'm pregnant, breastfeeding, taking blood thinners, or managing diabetes?

Consult a health care practitioner prior to use if you are pregnant or breastfeeding, taking blood thinners (anticoagulant or antiplatelet medication), or if you have diabetes or take blood-sugar-lowering medication.

Is it vegan and allergen-friendly?

Yes - the capsules are vegan, organically sourced, non-GMO and gluten-free, with no artificial colours, flavours or preservatives.

Is CanPrev Multi-Mushroom Full Spectrum made in Canada?

Yes. It is formulated and made in Canada by CanPrev Natural Health Products Ltd. (Scarborough, ON) and licensed by Health Canada under NPN 80129458.

Does this contain caffeine or stimulants?

No. None of the 7 mushroom species in this blend are stimulants. The only medicinal ingredients are the fruiting-body extracts and cultured mycelia of Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake and Turkey Tail.

490 mg Full-Spectrum 7-Mushroom Blend, 1-2x daily60 capsules · up to 2-month supplyVegan · Organically Sourced · Non-GMO · Gluten-FreeMade in Canada

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Natural Health Product NPN 80129458. Source of fungal polysaccharides with immunomodulating properties. Provides antioxidants that help protect against free radicals. Research summaries on this page concern the individual mushroom species in this blend (Chaga, Cordyceps militaris, Lion's Mane, Maitake, Reishi, Shiitake, Turkey Tail) generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized uses. Read and follow the label. Consult a health care practitioner before use if you are pregnant, breastfeeding, taking blood thinners, or managing diabetes. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner prior to use if you are taking blood thinners (anticoagulant or antiplatelet medication), if you have diabetes or take blood-sugar-lowering medication, or if you are pregnant or breastfeeding. Discontinue use and consult a health care practitioner if you experience a hypersensitivity or allergic reaction. Keep out of reach of children.

Indications

Recommended Use or Purpose: Source of fungal polysaccharides with immunomodulating properties. Provides antioxidants that help protect against free radicals.

Ingredients

Medicinal Ingredients (each vegetable capsule contains): Chaga (fruiting body, Inonotus obliquus) 8:1 extract equivalent to 400 mg dry fruiting body (hot water and alcohol extract), 50 mg. Cordyceps militaris (fruiting body) 8:1 extract equivalent to 400 mg dry fruiting body (hot water and alcohol extract), 50 mg. Lion's Mane (fruiting body, Hericium erinaceus) 8:1 extract equivalent to 400 mg dry fruiting body (hot water and alcohol extract), 50 mg. Maitake (fruiting body, Grifola frondosa) 4:1 extract equivalent to 200 mg dry fruiting body (hot water extract), 50 mg. Reishi (fruiting body, Ganoderma lucidum) 8:1 extract equivalent to 400 mg dry fruiting body (hot water and alcohol extract), 50 mg. Shiitake (fruiting body, Lentinula edodes) 8:1 extract equivalent to 400 mg dry fruiting body (hot water extract), 50 mg. Turkey Tail (fruiting body, Trametes versicolor) 8:1 extract equivalent to 400 mg dry fruiting body (hot water extract), 50 mg. Chaga (cultured mycelia, Inonotus obliquus), 20 mg. Cordyceps (stroma, Ophiocordyceps sinensis), 20 mg. Lion's Mane (cultured mycelia, Hericium erinaceus), 20 mg. Maitake (cultured mycelia, Grifola frondosa), 20 mg. Reishi (cultured mycelia, Ganoderma lucidum), 20 mg. Shiitake (cultured mycelia, Lentinula edodes), 20 mg. Turkey Tail (cultured mycelia, Trametes versicolor), 20 mg. Non-medicinal Ingredients: Acacia gum, hypromellose, magnesium stearate.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule, 1 to 2 times per day, with food. Recommended Duration of Use: No specific duration restriction is stated on this product's Health Canada licence; as with any natural health product, consult a health care practitioner about use beyond a few months.

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Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.