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Health Canada NPN 80122550 50mg Elemental Magnesium · Magnesium L-Threonate Vegan · Non-GMO · Gluten-Free Made in Canada · Pro Essentials Formula
Magnesium L-Threonate 50mgMagnesium L-Threonate 50mg - benefits and key ingredients Magnesium L-Threonate 50mg - lifestyleMagnesium L-Threonate 50mg - ingredientsMagnesium L-Threonate 50mg - supplement facts panel

CanPrev Magnesium L-Threonate 50mg - Optimal Absorption | 120 Caps

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$41.25 CAD ($0.34 / capsule)
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BrandCanPrev
Serving1-3 capsules (50-150 mg elemental magnesium)
Licensed Natural Health ProductNPN 80122550
Quality StandardsMade in Canada
CountryMade in Canada Made in Canada

About this item

  • 50MG ELEMENTAL MAGNESIUM PER CAPSULE: Sourced from 667 mg of magnesium L-threonate, a patented chelated form of magnesium.
  • FLEXIBLE 1-TO-3-CAPSULE DAILY DOSING: Adolescents and adults (14 years and older) take 1 capsule, 1 to 3 times per day, so you can adjust your total daily dose.
  • SUPPORTS ENERGY METABOLISM & TISSUE FORMATION: Helps in energy metabolism and tissue formation.
  • HELPS MAINTAIN ELECTROLYTE BALANCE & MUSCLE FUNCTION: Helps to maintain normal electrolyte balance and helps to maintain normal muscle function, including the heart muscle.
  • CLEAN VEGAN FORMULA: Vegan vegetable capsules, free from GMOs, gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives and animal products - no added fillers or flavours.
  • PREMIUM CANADIAN QUALITY: Formulated and made in Canada by CanPrev - Pro Essentials line, licensed under Health Canada NPN 80122550.

Product Description

Magnesium L-Threonate 50mg - The Magnesium Form Studied for Brain Magnesium Levels

CanPrev Magnesium L-Threonate 50mg

CanPrev Magnesium L-Threonate delivers 50 mg of elemental magnesium per capsule, sourced from 667 mg of magnesium L-threonate - a patented chelate developed by MIT and Tsinghua University researchers specifically for its ability to raise magnesium levels in the brain. Health Canada has licensed this product to help in energy metabolism and tissue formation, to help maintain normal electrolyte balance, and to help maintain normal muscle function, including the heart muscle. The research on magnesium L-threonate's brain-magnesium and cognitive effects further down this page is educational and concerns the ingredient generally - it is not a claim about this finished product. Licensed Natural Health Product NPN 80122550.

CanPrev Magnésium L-Thréonate fournit 50 mg de magnésium élémentaire par capsule, provenant de 667 mg de L-thréonate de magnésium - un chélate breveté mis au point par des chercheurs du MIT et de l'Université Tsinghua, spécifiquement pour sa capacité à élever les niveaux de magnésium dans le cerveau. Santé Canada a homologué ce produit pour aider au métabolisme de l'énergie et à la formation des tissus, pour aider à maintenir un équilibre électrolytique normal, et pour aider à maintenir un bon fonctionnement des muscles, incluant le muscle du cœur. Les recherches sur les effets du L-thréonate de magnésium sur le magnésium cérébral et la fonction cognitive présentées plus bas sur cette page sont à caractère éducatif et concernent l'ingrédient de manière générale - il ne s'agit pas d'une allégation visant ce produit fini. Produit de santé naturel homologué. NPN 80122550.

Magnesium L-Threonate 50mg lifestyle
CanPrev Magnesium L-Threonate 50mg
50mg Elemental Magnesium · Magnesium L-Threonate · 667mg Chelate

One Capsule, A Patented Brain-Targeted Magnesium Form

50mg Elemental Magnesium as Magnesium L-Threonate (667mg) - Vegan, Non-GMO, Gluten-Free

50mg Elemental Magnesium, 667mg L-Threonate Chelate

Each capsule provides 50 mg of elemental magnesium sourced from 667 mg of magnesium L-threonate, the same chelated form studied in published human and animal research for raising brain magnesium levels.

Flexible 1-to-3-Capsule Daily Dosing

Adolescents and adults (14 years and older) take 1 capsule, 1 to 3 times per day, so the total daily dose can be adjusted from 50 mg up to 150 mg of elemental magnesium.

What Magnesium L-Threonate Supports

Magnesium L-threonate is a patented magnesium chelate researched for its distinct ability to elevate brain magnesium levels - here is what CanPrev Magnesium L-Threonate is licensed to support, alongside why researchers are interested in this specific form.

General Health Maintenance

A factor in the maintenance of good health.

Energy Metabolism & Tissue Formation

Helps in energy metabolism and tissue formation.

Electrolyte Balance & Muscle Function

Helps to maintain normal electrolyte balance and normal muscle function, including the heart muscle.

A Form Researched for Brain Magnesium

Magnesium L-threonate is the chelate studied in published research for its distinct ability to raise magnesium levels in the brain - see the research summaries below for details (educational, not a claim about this finished product).

CanPrev Magnesium L-Threonate 50mg: Supplement Facts

CanPrev™Magnesium L-Threonate 50mg
English

Supplement Facts

  • Magnesium (Magnesium L-Threonate) per capsule, sourced from magnesium L-threonate 667 mg50 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Brown rice flour, hypromellose, magnesium stearate, microcrystalline cellulose.

Recommended Use or Purpose: A factor in the maintenance of good health. Helps in energy metabolism and tissue formation. Helps to maintain normal electrolyte balance. Helps to maintain normal muscle function, including the heart muscle.

Recommended Dose (Adolescents and Adults 14 years of age and older): Take 1 capsule, 1 to 3 times per day.

Cautions and Warnings: Keep out of reach of children. Do not use if the safety seal is broken.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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Fiche produit

  • Magnésium (L-Thréonate de magnésium) par capsule, provenant de L-thréonate de magnésium 667 mg50 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Farine de riz brun, hypromellose, stéarate de magnésium, cellulose microcristalline.

Usage ou fins recommandés : Un facteur contribuant au maintien d'une bonne santé. Aide au métabolisme de l'énergie et à la formation des tissus. Aide à maintenir un équilibre électrolytique normal. Aide à maintenir un bon fonctionnement des muscles, incluant le muscle du cœur.

Posologie recommandée (adolescents et adultes de 14 ans et plus) : Prendre 1 capsule, 1 à 3 fois par jour.

Mises en garde : Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.

NPN 80122550

50mg Elemental Magnesium · Magnesium L-Threonate667mg L-Threonate Chelate · Vegan120 Capsules · 1-3/DayMade in Canada

A patented magnesium form for everyday wellness

Get CanPrev Magnesium L-Threonate 50mg on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev Magnesium L-Threonate

A patented magnesium L-threonate chelate providing 50mg of elemental magnesium per capsule, with flexible 1-to-3-capsule daily dosing - premium CanPrev quality.

Patented L-Threonate Chelate

Magnesium bound to L-threonate, the specific chelate first developed by MIT and Tsinghua University researchers and studied for raising brain magnesium levels.

50mg Elemental Magnesium, 667mg Chelate

Each capsule supplies 50mg of elemental magnesium sourced from 667mg of magnesium L-threonate.

A factor in the maintenance of good health

Helps in energy metabolism and tissue formation, helps maintain normal electrolyte balance, and helps maintain normal muscle function, including the heart muscle.

Premium Canadian brand

CanPrev - Pro Essentials line, formulated and made in Canada. NPN 80122550.

How to use it

Take 1 capsule, 1 to 3 times per day

Adolescents and adults (14 years and older) take one (1) capsule, one (1) to three (3) times per day.

Start with 1 capsule and adjust

The flexible dosing range lets you start with a single capsule and increase gradually to find your comfortable daily dose.

Keep the seal intact

Do not use if the safety seal is broken.

Consult a practitioner if unsure

As with any natural health product, consult a health care practitioner on the use of this product.

What the research says about magnesium L-threonate

Educational summaries of published research on magnesium L-threonate and magnesium generally; not product-specific claims. CanPrev Magnesium L-Threonate's authorized claims under NPN 80122550 are: a factor in the maintenance of good health, helps in energy metabolism and tissue formation, helps to maintain normal electrolyte balance, and helps to maintain normal muscle function, including the heart muscle.

Magnesium L-Threonate & Cognitive Function (Human Trials)

Magtein-based formula improved memory and cognition in healthy adults

A double-blind, placebo-controlled trial in 109 healthy Chinese adults aged 18-65 found that a magnesium L-threonate (Magtein)-based formula produced significant improvements over placebo in all five subcategories of a standardized clinical memory test, and in overall memory quotient scores, after 30 days - with older participants showing more improvement than younger ones.

Human RCT
Zhang et al., Nutrients (2022)
Magnesium L-Threonate & Cognitive Function (Human Trials)

MMFS-01 (magnesium L-threonate) improved overall cognitive ability in older adults

A randomized, double-blind, placebo-controlled trial in adults aged 50-70 with cognitive impairment found that 12 weeks of MMFS-01, a magnesium L-threonate compound, significantly improved a composite score of overall cognitive ability compared with placebo, with the largest gains in executive function.

Human RCT
Liu et al., Journal of Alzheimer's Disease (2016)
Magnesium L-Threonate & Cognitive Function (Human Trials)

Review describes magnesium L-threonate among the more bioavailable forms for neuronal health

A 2024 review of magnesium's role in neuronal health describes magnesium-L-threonate (MgLT) and other bioavailable magnesium compounds as having shown promising results in enhancing synaptic density, improving memory function and alleviating symptoms of mental health disorders, while calling for further research.

Review
Kumar et al., Current Pharmaceutical Design (2024)
Magnesium L-Threonate & Brain Magnesium (Preclinical Mechanisms)

Foundational study: a new magnesium compound elevated brain magnesium and improved memory in rats

The study that first identified magnesium-L-threonate (MgT) found that raising brain magnesium with this compound enhanced learning, working memory, and short- and long-term memory in rats, and increased synapse density in the hippocampus that correlated with the memory improvements.

Preclinical study
Slutsky et al., Neuron (2010)
Magnesium L-Threonate & Brain Magnesium (Preclinical Mechanisms)

Threonate itself was shown to directly raise intraneuronal magnesium in neuron cultures

A mechanistic study found that threonate - the amino-acid-like component of magnesium L-threonate - directly increased intracellular magnesium concentration in cultured hippocampal neurons and in human neural stem cell-derived neurons, upregulating synapse-related signaling in a way other magnesium salts did not replicate.

Preclinical study
Sun et al., Neuropharmacology (2016)
Magnesium L-Threonate & Brain Magnesium (Preclinical Mechanisms)

Elevating brain magnesium reversed synapse loss in an Alzheimer's mouse model

A study in a transgenic Alzheimer's disease mouse model found that magnesium-L-threonate treatment reduced amyloid-beta plaque, prevented synapse loss, and reversed memory decline, with benefits observed even when treatment began at a late stage of disease-like pathology.

Preclinical study
Li et al., Molecular Brain (2014)
Magnesium L-Threonate & Sleep Quality

Magnesium-L-threonate improved deep and REM sleep in a 21-day trial

A randomized, double-blind, placebo-controlled trial in adults with self-reported sleep problems found that magnesium-L-threonate (1 g/day) improved deep sleep and REM sleep scores, daytime energy, mood and alertness, measured objectively with a sleep-tracking ring, compared with placebo over 21 days.

Human RCT
Hausenblas et al., Sleep Medicine: X (2024)
Magnesium L-Threonate & Sleep Quality

Magnesium bisglycinate modestly reduced insomnia severity

A randomized, placebo-controlled trial in 155 adults with poor sleep quality found that 250 mg of elemental magnesium as magnesium bisglycinate (a different chelate than L-threonate) produced a small but statistically significant reduction in Insomnia Severity Index scores after 4 weeks compared with placebo.

Human RCT
Schuster et al., Nature and Science of Sleep (2025)
Magnesium L-Threonate & Sleep Quality

Sleep quality scores improved alongside magnesium status in older adults

A controlled trial in adults over 51 with poor sleep quality found that Pittsburgh Sleep Quality Index scores improved and erythrocyte magnesium increased over 7 weeks, though the improvement occurred in both the magnesium-citrate and placebo groups, leaving magnesium's specific contribution unclear.

Human RCT
Nielsen et al., Magnesium Research (2010)
Magnesium & Muscle Cramps

Cochrane review found no meaningful benefit for cramp prevention in older adults

An updated Cochrane review of 11 trials (735 participants) concluded that oral magnesium supplementation is unlikely to provide clinically meaningful cramp prophylaxis for older adults with idiopathic nocturnal leg cramps, though evidence for pregnancy-related cramps remained conflicting.

Cochrane Review
Garrison et al., Cochrane Database of Systematic Reviews (2020)
Magnesium & Muscle Cramps

Meta-analysis found no reduction in pregnancy leg cramp frequency

A meta-analysis of 4 randomized controlled trials (332 pregnant women) found that oral magnesium supplementation did not significantly decrease the frequency of leg cramps compared with control, and did not significantly improve recovery from cramps.

Meta-analysis
Liu et al., Taiwanese Journal of Obstetrics & Gynecology (2021)
Magnesium & Muscle Cramps

Observational trial found no advantage over placebo for pregnancy leg cramps

A controlled trial of 130 pregnant women with leg cramps found a similar reduction in cramp frequency in both the oral magnesium citrate group and the placebo group after 4 weeks, with no significant difference between them.

Human RCT
Araujo et al., PLoS One (2020)
Magnesium's Role in Energy Metabolism & Cellular Function

Magnesium acts as a cofactor in over 300 enzymatic reactions

A comprehensive review describes magnesium as a cofactor for more than 300 enzymatic reactions, essential for converting ATP to ADP for energy production, as well as for protein synthesis, DNA synthesis and muscle contraction throughout the body.

Review
Fatima et al., Cureus (2024)
Magnesium's Role in Energy Metabolism & Cellular Function

Magnesium is essential for ion channel function, nerve transmission and vasomotor tone

A review of magnesium's physiological roles describes its involvement as a cofactor in ATP metabolism and its role in regulating ion channels, muscular contraction, cardiac excitability, vasomotor tone, nerve transmission and neuromuscular conduction.

Review
Grober et al., Nutrients (2015)
Magnesium's Role in Energy Metabolism & Cellular Function

Magnesium is a required cofactor for activating vitamin D

A review found that the enzymes that metabolize vitamin D in the liver and kidneys all appear to require magnesium as a cofactor, linking adequate magnesium intake to the body's ability to properly activate and use vitamin D.

Review
Uwitonze & Razzaque, The Journal of the American Osteopathic Association (2018)
Magnesium & Cardiovascular Health

Meta-analysis found magnesium supplementation modestly lowered blood pressure

A meta-analysis of 38 randomized controlled trials (2,709 participants) found magnesium supplementation reduced systolic blood pressure by 2.81 mmHg and diastolic blood pressure by 2.05 mmHg compared with placebo, with larger reductions in those with hypertension or low magnesium status.

Meta-analysis
Argeros et al., Hypertension (2025)
Magnesium & Cardiovascular Health

Dietary magnesium intake is inversely associated with cardiovascular risk factors

A review of electrolyte minerals and cardiovascular health found that, unlike sodium, dietary magnesium (along with potassium and calcium) shows an inverse correlation with cardiovascular events and risk factors, particularly blood pressure.

Review
Mohammadifard et al., Critical Reviews in Food Science and Nutrition (2018)
Magnesium & Cardiovascular Health

Magnesium reduced new-onset atrial fibrillation after cardiac surgery

A meta-analysis of 24 randomized controlled trials (3,373 participants) found that magnesium supplementation reduced the risk of new-onset atrial fibrillation following cardiac surgery, with high-certainty evidence in lower-bias trials, though it had no significant effect on all-cause mortality.

Meta-analysis
Ghazizadeh et al., Heart International (2025)
Magnesium & Bone Health

Updated review confirms magnesium's link to bone mineral density

An updated narrative review of 28 studies found that lower serum magnesium is associated with osteoporosis, that roughly a fifth of people consistently consume less magnesium than recommended, and that magnesium supplementation trials showed benefits for both bone mineral density and fracture risk.

Review
Rondanelli et al., Biometals (2021)
Magnesium & Bone Health

Higher magnesium intake linked to higher hip bone mineral density in older adults

A systematic review and meta-analysis of studies in adults 60 and older found a significant positive association between magnesium intake and hip bone mineral density, though evidence for other bone sites and fracture outcomes was more limited.

Meta-analysis
Groenendijk et al., Bone (2021)
Magnesium & Bone Health

Lower serum magnesium independently associated with osteoporosis risk

A retrospective study of 496 postmenopausal women found that lower serum magnesium levels were independently associated with higher odds of osteoporosis and osteoporotic fractures, after adjusting for age, BMI and other bone-turnover markers.

Observational study
Shi et al., Frontiers in Medicine (2026)
Magnesium Deficiency & Global Intake Gaps

Modelling study estimates widespread inadequate magnesium intake worldwide

A global modelling analysis covering 185 countries found estimated inadequate-intake rates were higher for men than women for several nutrients including magnesium, part of a broader pattern of common micronutrient intake gaps worldwide.

Modelling Study
Passarelli et al., The Lancet Global Health (2024)
Magnesium Deficiency & Global Intake Gaps

Review frames magnesium deficiency as an underappreciated public health issue

A 2025 review describes magnesium as a critical cofactor in hundreds of enzymatic reactions and links widespread low magnesium status - driven by inadequate dietary intake, chronic disease and lifestyle factors - to elevated risks across cardiometabolic, skeletal and neurological health.

Review
Matek Saric et al., Nutrients (2025)
Magnesium Deficiency & Global Intake Gaps

Review estimates roughly a third of the global population falls short on magnesium

A 2025 review estimates that approximately 2.4 billion people, or about 31% of the global population, do not meet recommended magnesium intake levels, driven by modern dietary patterns, soil depletion and food processing losses.

Review
Zhang & Zhao, International Journal for Vitamin and Nutrition Research (2025)

Frequently asked questions

What is CanPrev Magnesium L-Threonate and what does it do?

It's a magnesium supplement providing 50mg of elemental magnesium per capsule, sourced from 667mg of magnesium L-threonate. Magnesium is a factor in the maintenance of good health, and helps in energy metabolism and tissue formation, helps maintain normal electrolyte balance, and helps maintain normal muscle function, including the heart muscle.

How do I take it?

Adolescents and adults (14 years and older) take 1 capsule, 1 to 3 times per day.

What makes magnesium L-threonate different from other magnesium forms?

Magnesium L-threonate is a patented chelate of magnesium bound to L-threonate, first developed by researchers at MIT and Tsinghua University because it was found in research to raise magnesium levels in the brain more effectively than other common magnesium forms. This finished product is licensed for general health maintenance, energy metabolism, electrolyte balance and muscle function - the brain-magnesium research referenced on this page is educational and general to the ingredient, not a claim about this specific product.

How many capsules are in a bottle, and how long does it last?

Each bottle contains 120 vegetable capsules. At 1 capsule daily that's a 120-day supply; at the full 3-capsules-per-day dose it's about a 40-day supply.

Is it vegan?

Yes - the vegetable capsule and all ingredients are vegan, with a clean formula free of GMOs, gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives and animal products.

Does it contain any other minerals or added ingredients?

No - the sole medicinal ingredient is magnesium (as magnesium L-threonate), 50mg elemental per capsule. Non-medicinal ingredients are brown rice flour, hypromellose, magnesium stearate and microcrystalline cellulose - no added flavours or fillers.

Who should use caution, or not use it?

As with any natural health product, consult a health care practitioner on the use of this product. Do not use if the safety seal is broken. Keep out of reach of children.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

50mg Elemental Magnesium · Magnesium L-Threonate667mg L-Threonate Chelate · Vegan120 Capsules · 1-3/DayMade in Canada

A patented magnesium form for everyday wellness

Get CanPrev Magnesium L-Threonate 50mg on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80122550. Helps in energy metabolism and tissue formation, helps to maintain normal electrolyte balance, and helps to maintain normal muscle function, including the heart muscle. The research summaries below concern magnesium and magnesium L-threonate generally and are educational - they are not claims about this finished product. Read and follow the label. As with any natural health product, consult a health care practitioner on the use of this product. Do not use if the safety seal is broken. Results may vary.

Important information

Safety Information

Cautions and Warnings: Keep out of reach of children. Do not use if the safety seal is broken.

Indications

Recommended Use or Purpose: A factor in the maintenance of good health. Helps in energy metabolism and tissue formation. Helps to maintain normal electrolyte balance. Helps to maintain normal muscle function, including the heart muscle.

Ingredients

Medicinal ingredient (per capsule): Magnesium (Magnesium L-Threonate) 50 mg, sourced from magnesium L-threonate 667 mg. Non-medicinal ingredients: Brown rice flour, hypromellose, magnesium stearate, microcrystalline cellulose. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adolescents and Adults 14 years of age and older): Take 1 capsule, 1 to 3 times per day.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.