CanPrev Lutein 20 - Blue Light Defence | 60 Softgels
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 softgel daily |
| Licensed Natural Health Product | NPN 80088829 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- 20 MG LUTEIN WITH ZEAXANTHIN AND MESO-ZEAXANTHIN: Each softgel provides the naturally-occurring 20:2:2 ratio of 20 mg Lutein (from Lutemax 2020 marigold extract, Tagetes erecta flower), 2 mg Zeaxanthin and 2 mg Meso-Zeaxanthin for Five-Factor Eye Support.
- HELPS PROTECT AGAINST BLUE LIGHT AND OXIDATIVE DAMAGE: This product's Health Canada-authorized use: helps to protect the eyes against both blue light and oxidative damage.
- SUPPORTS EYE HEALTH IN CATARACTS AND AGE-RELATED MACULAR DEGENERATION: Helps to support eye health in conditions such as cataracts and age-related macular degeneration, and helps improve contrast sensitivity, visual acuity, and glare recovery.
- CLINICALLY PROVEN TO HELP IMPROVE MACULAR PIGMENT OPTICAL DENSITY: The label's own authorized claim: clinically proven to help improve macular pigment optical density, the diet-derived protective layer that filters blue light in the retina.
- ONE SOFTGEL A DAY: Adults take one (1) softgel per day, or as directed by a healthcare practitioner - a 60-day supply per bottle.
- MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated and made in Canada by CanPrev Natural Health Products Ltd. (Toronto, ON) and licensed under NPN 80088829. Non-GMO, gluten-free, dairy-free, with no artificial colours, flavours or preservatives.
Product Description
Lutein 20 - Blue Light Defence, 20 mg Lutein with Zeaxanthin and Meso-Zeaxanthin
Lutein 20 delivers the naturally-occurring 20:2:2 ratio of the three macular carotenoids - 20 mg Lutein (from Lutemax 2020 marigold extract), 2 mg Zeaxanthin and 2 mg Meso-Zeaxanthin - in one daily softgel for Five-Factor Eye Support. Helps to protect the eyes against both blue light and oxidative damage, and helps to support eye health in conditions such as cataracts and age-related macular degeneration while improving contrast sensitivity, visual acuity, and glare recovery. Clinically proven to help improve macular pigment optical density. Non-GMO and licensed as a Natural Health Product. Licensed Natural Health Product NPN 80088829.
Lutein 20 fournit le rapport 20:2:2 naturellement present des trois carotenoides maculaires - 20 mg de lutein (extrait de souci Lutemax 2020), 2 mg de zeaxanthine et 2 mg de meso-zeaxanthine - en une seule gelule par jour pour un soutien oculaire en cinq facteurs. Aide a proteger les yeux contre la lumiere bleue et les dommages oxydatifs, et aide a soutenir la sante oculaire dans des conditions telles que les cataractes et la degenerescence maculaire liee a l'age, tout en ameliorant la sensibilite aux contrastes, l'acuite visuelle et la readaptation apres eblouissement. Prouve cliniquement pour aider a ameliorer la densite optique du pigment maculaire. Sans OGM et homologue comme produit de sante naturel.
Built for Blue Light Defence
20 mg Lutein (Lutemax 2020) + 2 mg Zeaxanthin + 2 mg Meso-Zeaxanthin - the eye's own natural 20:2:2 carotenoid ratio, in one daily softgel
20 mg Lutein, 2 mg Zeaxanthin, 2 mg Meso-Zeaxanthin
Each softgel delivers the naturally-occurring 20:2:2 ratio of the three macular carotenoids (from Lutemax 2020 marigold extract, Tagetes erecta flower) - take 1 softgel daily, or as directed by a healthcare practitioner.
Five-Factor Eye Support
Helps protect against blue light and oxidative damage, supports eye health in cataracts and age-related macular degeneration, and helps improve contrast sensitivity, visual acuity and glare recovery.
Why This Formula
Lutein 20 is built around the same three macular carotenoids - lutein, zeaxanthin and meso-zeaxanthin - that make up the eye's own natural protective pigment, in the ratio found in a healthy retina.
Blue Light & Oxidative Defence
Helps to protect the eyes against both blue light and oxidative damage - this product's Health Canada-authorized use.
20 mg Lutein + 2 mg Zeaxanthin + 2 mg Meso-Zeaxanthin
Delivers the naturally-occurring 20:2:2 ratio of all three macular carotenoids in a single daily softgel.
Cataract & AMD Eye-Health Support
Helps to support eye health in conditions such as cataracts and age-related macular degeneration.
Contrast, Acuity & Glare Recovery
Helps improve contrast sensitivity, visual acuity, and glare recovery - and is clinically proven to help improve macular pigment optical density.
CanPrev Lutein 20 - Blue Light Defence: Supplement Facts
Each softgel contains:
- Lutein (from Lutemax 2020 marigold extract, Tagetes erecta flower)20 mg
- Zeaxanthin2 mg
- Meso-Zeaxanthin2 mg
Non-Medicinal Ingredients: Natural tocopherols, safflower oil, sunflower oil, sunflower lecithin, gelatin, glycerin, yellow beeswax, purified water.
Recommended Use or Purpose: Helps to protect the eyes against both blue light and oxidative damage. Helps to support eye health in conditions such as cataracts and age-related macular degeneration and improve contrast sensitivity, visual acuity, and glare recovery. Clinically proven to help improve macular pigment optical density.
Recommended Dose (Adults): Take one (1) softgel per day, or as directed by a healthcare practitioner.
Cautions and Warnings: As with any natural health product, consult a healthcare practitioner prior to use of this product, especially if you are pregnant or breastfeeding. Do not use if the safety seal is broken. Known Adverse Reactions: Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.
Chaque gelule contient :
- Lutein (extrait de souci Lutemax 2020, fleur de Tagetes erecta)20 mg
- Zeaxanthine2 mg
- Meso-zeaxanthine2 mg
Ingrédients non médicinaux : Tocopherols naturels, huile de carthame, huile de tournesol, lecithine de tournesol, gelatine, glycerine, cire d'abeille jaune, eau purifiee.
Usage ou fins recommandes : Aide a proteger les yeux contre la lumiere bleue et les dommages oxydatifs. Aide a soutenir la sante oculaire dans des conditions telles que les cataractes et la degenerescence maculaire liee a l'age, et ameliore la sensibilite aux contrastes, l'acuite visuelle et la readaptation apres eblouissement. Prouve cliniquement pour aider a ameliorer la densite optique du pigment maculaire.
Dose recommandee (adultes) : Prendre une (1) gelule par jour, ou selon l'avis d'un praticien de soins de sante.
Mises en garde et avertissements : Comme avec tout produit de sante naturel, consultez un praticien de soins de sante avant l'utilisation de ce produit, surtout si vous etes enceinte ou allaitante. Ne pas utiliser si le sceau de securite est brise. Reactions indesirables connues : Ne pas utiliser si vous etes allergique aux plantes de la famille des Asteracees/Composees/Marguerites. Tenir hors de la portee des enfants.
NPN 80088829
Add CanPrev Lutein 20 - Blue Light Defence to your daily routine
Get CanPrev Lutein 20 on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Lutein 20
20 mg Lutein, 2 mg Zeaxanthin and 2 mg Meso-Zeaxanthin in the eye's own natural 20:2:2 ratio, for Five-Factor Eye Support in one daily softgel.
20 mg Lutein + 2 mg Zeaxanthin + 2 mg Meso-Zeaxanthin
Each softgel delivers the naturally-occurring 20:2:2 ratio of all three macular carotenoids from Lutemax 2020 marigold extract.
Blue light and oxidative defence
Helps to protect the eyes against both blue light and oxidative damage - the label's authorized use.
Cataract and AMD eye-health support
Helps to support eye health in conditions such as cataracts and age-related macular degeneration, and helps improve contrast sensitivity, visual acuity, and glare recovery.
Trusted Canadian brand
CanPrev - formulated and made in Canada, licensed under NPN 80088829.
Inside every softgel
20 mg Lutein (from Lutemax 2020 marigold extract) plus 2 mg Zeaxanthin and 2 mg Meso-Zeaxanthin - take 1 softgel per day, or as directed by a healthcare practitioner.
How to use it
Take one softgel daily
Adults take one (1) softgel per day, or as directed by a healthcare practitioner.
Take it with a meal
Lutein, zeaxanthin and meso-zeaxanthin are fat-soluble carotenoids best absorbed alongside food.
Give it time
Macular pigment builds gradually with consistent daily use - take it as part of your everyday routine, especially with regular screen exposure.
What the research says about Lutein, Zeaxanthin & Meso-Zeaxanthin
Educational summaries of published research on lutein, zeaxanthin and meso-zeaxanthin generally; not product-specific claims. CanPrev Lutein 20's own label claim is the use authorized under NPN 80088829: helps protect the eyes against both blue light and oxidative damage, helps support eye health in conditions such as cataracts and age-related macular degeneration, helps improve contrast sensitivity, visual acuity and glare recovery, and is clinically proven to help improve macular pigment optical density.
Higher macular pigment density improved detection of hazy, low-contrast targets in a vision study
In 58 healthy young adults, higher macular pigment optical density (MPOD) was significantly linked to a greater ability to detect low- and mid-frequency visual targets veiled by simulated blue-toned haze, supporting the idea that macular pigment helps filter short-wavelength light that degrades distance vision.
Human studyA study in children found no measurable link between diet-derived macular pigment and visual performance
In 36 healthy children with medium-to-high adherence to a Mediterranean diet, researchers found no significant correlation between macular pigment optical density and visual acuity or contrast sensitivity - an honest null result that may reflect the already-adequate lutein/zeaxanthin intake of this well-nourished pediatric sample.
Cross-sectional studyA head-to-head trial found a higher-dose, meso-zeaxanthin-containing formula raised macular pigment more than a standard AREDS2-style supplement
Comparing a 28 mg lutein/zeaxanthin/meso-zeaxanthin liquid supplement against a 12 mg AREDS2-style softgel over 24 weeks, the higher-dose triple-carotenoid formula produced roughly 3 to 4-fold greater serum absorption and a significant rise in macular pigment optical density, while the AREDS2-style formula's MPOD stayed essentially flat.
Human RCTA study of 57 children and teens found more than 2 hours of daily smartphone use was linked to lower macular pigment levels
Measuring macular pigment optical density in 114 eyes of children and adolescents aged 8-18, researchers found a strong association between longer smartphone screen time and lower macular pigment in both eyes, with levels measurably lower in those exceeding 2 hours of daily use versus those under it.
Cross-sectional studyA 600-participant trial is underway testing lutein, zeaxanthin and omega-3 supplementation in heavy digital-device users
This registered 24-week, multicenter, randomized, double-blind, placebo-controlled trial (the LZO study) is enrolling adults who use digital devices over 8 hours daily to measure changes in macular pigment optical density, contrast and glare sensitivity, and other visual-function outcomes versus placebo.
Registered clinical trial (ongoing)Six months of macular carotenoid supplementation improved visual performance and reduced eye strain in adults with high screen time
In 48 healthy young adults with at least 6 hours of daily near-field screen exposure, 24 mg daily of lutein, zeaxanthin and meso-zeaxanthin significantly raised macular pigment optical density and improved contrast sensitivity, glare disability, photostress recovery, headache frequency, eye strain, eye fatigue and sleep quality versus placebo.
Human RCTThe landmark AREDS2 trial found adding lutein and zeaxanthin to the original AMD formula was a safer substitute for beta-carotene, without a significant added benefit on its own
In this 4,203-participant multicenter randomized trial, adding lutein (10 mg) + zeaxanthin (2 mg) to the AREDS antioxidant formula did not significantly reduce progression to advanced age-related macular degeneration versus placebo over 5 years - but because the beta-carotene arm was linked to more lung cancers in former smokers, the study concluded lutein + zeaxanthin is an appropriate, safer carotenoid substitute in the formula.
Human RCTA 10-year AREDS2 follow-up found lutein/zeaxanthin carried a lower lung-cancer risk than beta-carotene and a modest AMD-progression benefit
Following 3,882 AREDS2 participants for a decade, beta-carotene nearly doubled lung cancer risk while lutein/zeaxanthin showed no significant increase; lutein/zeaxanthin also showed a statistically significant association with slower progression to late AMD compared with beta-carotene.
Human RCT (10-year follow-up)Post-hoc AREDS2 analysis found lutein/zeaxanthin supplementation slowed geographic atrophy's advance toward the central macula
Analyzing 1,210 AREDS2 eyes with geographic atrophy (an advanced dry-AMD lesion), progression of the atrophy toward the central macula was significantly slower in participants randomized to lutein/zeaxanthin versus those who were not (80.1 vs 114.4 micrometers/year), consistent with a protective effect on the fovea specifically.
Post-hoc RCT analysisA 12-month trial found macular carotenoid supplementation measurably improved contrast sensitivity
In the CREST trial, 53 adults with low retinal carotenoid levels took 10 mg lutein + 2 mg zeaxanthin + 10 mg meso-zeaxanthin daily for 12 months; contrast sensitivity improved significantly versus placebo at multiple spatial frequencies, and the improvement tracked with the rise in retinal carotenoid concentration.
Human RCTA 1-year placebo-controlled trial found lutein and zeaxanthin improved photostress recovery time and chromatic contrast
In 115 healthy young adults randomized to 10 mg lutein + 2 mg zeaxanthin daily or placebo for a year, macular pigment optical density rose significantly at every measured retinal location, and both chromatic contrast sensitivity and photostress recovery time (how fast vision returns after a bright flash) improved significantly versus placebo.
Human RCTHigher-dose macular carotenoid supplementation improved glare tolerance and photostress recovery over 12 months
In 59 young adults supplementing with either 10 mg or 20 mg lutein (plus proportional zeaxanthin/meso-zeaxanthin) daily, both doses significantly raised macular pigment and improved disability-glare thresholds and photostress recovery time versus placebo at 6 and 12 months.
Human RCTA clinical review found consistent evidence that dietary lutein, zeaxanthin and meso-zeaxanthin support retinal health across multiple eye conditions
This review of epidemiological studies and clinical trials found that higher dietary intake and serum levels of lutein and zeaxanthin are consistently associated with lower risk of age-related macular degeneration (especially the late/neovascular form), and that supplementation raises macular pigment, improves visual function, and shows encouraging early evidence for cataracts, diabetic retinopathy and retinopathy of prematurity.
ReviewAn 18-month RCT found the lutein/zeaxanthin/meso-zeaxanthin combination raised macular pigment even in eyes with glaucoma
In 62 participants with open-angle glaucoma, supplementing 10 mg lutein + 2 mg zeaxanthin + 10 mg meso-zeaxanthin daily produced a statistically significant, sustained rise in macular pigment optical density over 18 months versus placebo (which showed no change), along with a significant improvement in glare-condition contrast sensitivity; no serious adverse events were noted.
Human RCTA head-to-head trial in early AMD found a meso-zeaxanthin-containing formula improved contrast sensitivity faster than a standard AREDS2 softgel
In 56 participants with early sub-clinical AMD (retinal drusen), a micronized lutein/zeaxanthin/meso-zeaxanthin liquid supplement produced statistically significant improvements in contrast sensitivity within 3 months, an effect that did not reach significance in the comparison group taking a standard AREDS2-style softgel without meso-zeaxanthin over the same 6-month period.
Human RCTA large US health-survey analysis found higher blood carotenoid levels were linked to lower cataract risk, especially in women
Among 1,478 US adults aged 50+ in NHANES data, those in the highest quartile of serum lutein/zeaxanthin had significantly lower odds of cataract than those in the lowest quartile; the protective association with overall eye disease risk was significant in women but not observed in men in subgroup analysis.
Observational study (NHANES)The FDA's own evidence review found the science did not yet meet the bar for an official lutein/zeaxanthin health claim on cataracts or AMD
Reviewing the same intervention and observational evidence under its formal significant-scientific-agreement standard, the FDA concluded in this 2006 evaluation that the evidence did not support an approved US health claim linking lutein or zeaxanthin intake to reduced risk of age-related macular degeneration or cataracts - an honest regulatory caveat distinct from the underlying research base, and from Health Canada's own separate NPN authorization for this product.
Regulatory evidence reviewA study in cataract-surgery patients found lutein supplementation raised macular pigment starting within a week
In 57 patients who had undergone cataract surgery with an intraocular lens implant, macular pigment optical density rose significantly after just 1 week of lutein supplementation and stayed elevated; the increase was larger in patients who started with the lowest baseline levels and in women.
Human studyA 2026 RCT in teenagers with high screen use found lutein and zeaxanthin supplementation raised macular pigment and improved attention and processing speed
In 82 teenagers aged 13-18 with high screen use and low fruit/vegetable intake, 6 months of 10 mg lutein + 2 mg zeaxanthin daily significantly increased macular pigment optical density in both eyes and improved attention and processing-speed test scores versus placebo, though it did not significantly change visual reasoning, nonverbal memory, or self-reported sleep.
Human RCTThe AREDS2 cognitive-function sub-study found no significant benefit from lutein/zeaxanthin or omega-3s in older adults with AMD
Testing over 3,500 AREDS2 participants (mean age 73) with validated cognitive test batteries over 5 years, this large randomized trial found no statistically significant difference in cognitive-function change between those given lutein/zeaxanthin or long-chain omega-3s and those who were not - an honest null result specific to this older, AMD-risk population.
Human RCTA combination of omega-3s, lutein and zeaxanthin improved memory in older adults who already had cognitive decline, but not in those without it
Across two randomized, placebo-controlled trials in healthy older Japanese adults with memory complaints, a supplement combining long-chain omega-3 fatty acids with lutein and zeaxanthin did not significantly change memory scores overall, but did significantly improve memory function in the subgroup who already had measurable cognitive decline at baseline.
Human RCTA prospective study of nearly 2,700 eyes found diet, including lutein and zeaxanthin intake, measurably slowed AMD progression
Following eyes with early or intermediate AMD for 5 years, higher intake of green leafy vegetables, fish, and lutein/zeaxanthin (at least 2 mg/day) were each independently associated with a significantly lower rate of progressing to more advanced disease stages, after adjusting for genetics, lifestyle and other risk factors.
Prospective cohort studyA 2025 review confirms lutein and zeaxanthin as part of the only nutrient combination proven to slow AMD progression
Reviewing modifiable lifestyle risk factors for age-related macular degeneration, this article highlights that the AREDS/AREDS2 formula, combining vitamins C and E, zinc, copper, lutein and zeaxanthin, remains a supplement combination shown to significantly reduce the risk of AMD progressing from dry to wet (advanced) disease, alongside smoking cessation and a Mediterranean-style diet.
ReviewAn umbrella review found suggestive evidence that dietary lutein and zeaxanthin intake is associated with lower cataract risk
Pooling 25 meta-analyses and 10 systematic reviews on smoking and diet in age-related eye disease, this umbrella review rated the evidence linking dietary lutein, zeaxanthin, omega-3 fatty acids and vitamin C intake to lower cataract risk as 'suggestive' (class III) - a real but more preliminary tier of evidence than the 'convincing' link found for smoking and cataract.
Umbrella reviewFrequently asked questions
How do I take CanPrev Lutein 20?
Adults take one (1) softgel per day, or as directed by a healthcare practitioner.
What's in each softgel?
Each softgel contains 20 mg Lutein (from Lutemax 2020 marigold extract, Tagetes erecta flower), 2 mg Zeaxanthin, and 2 mg Meso-Zeaxanthin. Non-medicinal ingredients are natural tocopherols, safflower oil, sunflower oil, sunflower lecithin, gelatin, glycerin, yellow beeswax and purified water.
What is the licensed use of this product?
This product's Health Canada licence (NPN 80088829) authorizes it to help protect the eyes against both blue light and oxidative damage, help support eye health in conditions such as cataracts and age-related macular degeneration, help improve contrast sensitivity, visual acuity, and glare recovery, and is clinically proven to help improve macular pigment optical density.
Why does this formula include zeaxanthin and meso-zeaxanthin, not just lutein?
Lutein, zeaxanthin and meso-zeaxanthin are the three carotenoids that make up macular pigment, the eye's own natural protective layer. This formula uses a 20:2:2 ratio to reflect that naturally-occurring balance, rather than lutein alone.
Can I take this if I'm pregnant or breastfeeding?
Consult a healthcare practitioner before use if you are pregnant or breastfeeding.
Are there any allergy considerations?
Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family, since the lutein in this product is sourced from a marigold (Tagetes erecta) extract, which belongs to that plant family.
Is it vegan and allergen-friendly?
It is non-GMO, gluten-free and dairy-free, with no artificial colours, flavours or preservatives. Note the softgel shell itself is gelatin-based, so it is not vegan.
Is CanPrev Lutein 20 made in Canada?
Yes. It is formulated and made in Canada by CanPrev Natural Health Products Ltd. (Toronto, ON) and licensed by Health Canada under NPN 80088829.
Add CanPrev Lutein 20 - Blue Light Defence to your daily routine
Get CanPrev Lutein 20 on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80088829. Helps to protect the eyes against both blue light and oxidative damage. Helps to support eye health in conditions such as cataracts and age-related macular degeneration and improve contrast sensitivity, visual acuity, and glare recovery. Research summaries on this page concern lutein, zeaxanthin and meso-zeaxanthin generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Consult a health care practitioner before use, especially if you are pregnant or breastfeeding. Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a healthcare practitioner prior to use of this product, especially if you are pregnant or breastfeeding. Do not use if the safety seal is broken. Known Adverse Reactions: Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps to protect the eyes against both blue light and oxidative damage. Helps to support eye health in conditions such as cataracts and age-related macular degeneration and improve contrast sensitivity, visual acuity, and glare recovery. Clinically proven to help improve macular pigment optical density.
Ingredients
Medicinal Ingredients (per 1 softgel): Lutein (from Lutemax 2020 marigold extract, Tagetes erecta flower), 20 mg; Zeaxanthin, 2 mg; Meso-Zeaxanthin, 2 mg. Non-medicinal Ingredients: Natural tocopherols, safflower oil, sunflower oil, sunflower lecithin, gelatin, glycerin, yellow beeswax, purified water.
Directions
Recommended Dose (Adults): Take one (1) softgel per day, or as directed by a healthcare practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.