CanPrev Liposomal Milk Thistle - Liver Support Liquid | 225mL
Visit the CanPrev Store| Brand | CanPrev |
| Serving | 1 teaspoon (5 mL), twice daily - 125 mg Milk Thistle per serving |
| Licensed Natural Health Product | NPN 80120059 |
| Quality Standards | GMP-compliant facility |
| Country of Manufacture | Made in USA · CanPrev, a Canadian Brand  |
About this item
- LIPOSOMAL DELIVERY FOR ENHANCED ABSORPTION: 125 mg of Milk Thistle (40:1 extract, standardized to 50% silymarin) per serving is delivered inside a bio-friendly phospholipid liposome, engineered for rapid and sustained cellular uptake compared with standard milk thistle capsules.
- SUPPORTS LIVER FUNCTION: Used in Herbal Medicine to help support liver function - milk thistle's active compound, silymarin, is the focus of most published liver research on this plant.
- DELICIOUS COCONUT CARAMEL NUT FLAVOUR: A pleasant coconut caramel nut flavoured liquid, with no alcohol added - an easy addition to a daily routine for anyone who prefers not to swallow capsules.
- PURE & PLANT-BASED: Vegan, non-GMO and crafted from milk thistle extract, made without artificial colours, flavours or preservatives.
- EASY LIQUID FORMAT: Just one teaspoon, twice a day - taken directly or mixed into a glass of water, instead of large milk thistle capsules.
- CONTAINS NUTS - CHECK THE LABEL: Formulated with macadamia nut oil as part of the liposomal base; contains nuts. Always verify allergens and cautions from the supplement-facts panel before use.
- USE CONSISTENTLY: Use this product for at least 3 weeks to see beneficial effects. Shake well before use and refrigerate after opening.
- CANPREV QUALITY: Formulated by CanPrev, a Health Canada-licensed natural health product company. NPN 80120059.
Product Description
Liposomal Milk Thistle - Enhanced Absorption Milk Thistle in Coconut Caramel Nut Liquid Form
125 mg of Milk Thistle (Silybum marianum seed, 40:1 extract, standardized to 50% silymarin) per teaspoon, delivered inside a bio-friendly phospholipid liposome for rapid and sustained cellular uptake - a smooth, coconut caramel nut flavoured liquid instead of another capsule. Used in Herbal Medicine to help support liver function. Licensed Natural Health Product NPN 80120059.
125 mg de chardon-Marie (Silybum marianum, graine, extrait 40:1, standardisé à 50 % de silymarine) par cuillère à thé, livré dans un liposome phospholipidique biocompatible pour une absorption cellulaire rapide et soutenue - un liquide onctueux au goût de caramel noix de coco plutôt qu'une autre capsule. Utilisé en phytothérapie pour appuyer les fonctions hépatiques. Produit de santé naturel homologué. NPN 80120059.
Liquid, Liposomal, and Built for Absorption
125mg Liposomal Milk Thistle per Serving - Vegan, Non-GMO, Gluten-Free, Coconut Caramel Nut Flavour
Liposomal Delivery System
Bio-friendly phospholipid bilayers envelop the milk thistle extract in a protective bubble, shielding it from digestive breakdown in transit and supporting rapid, sustained cellular uptake.
A Real Authorized Liver-Function Claim
Licensed under NPN 80120059 - Milk Thistle is used in Herbal Medicine to help support liver function.
What CanPrev Liposomal Milk Thistle Supports
Milk thistle's silymarin is one of the most studied plant extracts for liver health - but plain silymarin is notoriously poorly absorbed. Here is what liposomal delivery is formulated to address, and what the wider research on silymarin explores.
Liver Function Support
Used in Herbal Medicine to help support liver function - the focus of most of the published research on milk thistle's active compound, silymarin.
Antioxidant Mechanism
Silymarin is studied for its free-radical-scavenging and cell-membrane-stabilizing properties in liver tissue.
Enhanced Liposomal Absorption
The liposomal liquid format is designed to improve on the poor natural bioavailability of plain milk thistle extract, in a smooth coconut caramel nut flavoured liquid with no capsules.
Easy Daily Liquid Dose
One teaspoon, twice daily, taken directly or mixed with water - no capsules to swallow.
CanPrev Liposomal Milk Thistle: Supplement Facts
Supplement Facts
- Milk Thistle (Silybum marianum) seed, 40:1 extract, 50% silymarin per 1 teaspoon (5 mL)125 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Macadamia nut, sunflower oil, phosphatidylcholine, natural caramel flavour, natural coconut extract, organic vanilla extract, glycerin, citric acid, d-alpha tocopherol, purified water. Contains nuts.
Recommended Use or Purpose: Milk Thistle (Silybum marianum) is used in Herbal Medicine to help support liver function.
Recommended Dose (Adults): Take one (1) teaspoon (5 mL), two (2) times per day, or as directed by a health care practitioner. Can be taken directly or mixed with a glass of water. Duration of Use: Use for at least three (3) weeks to see beneficial effects. Shake well before use. Refrigerate after opening.
Cautions and Warnings: As with any natural health product, consult a health care practitioner before use, especially if you are pregnant or if symptoms persist or worsen. Do not use if the safety seal is broken. Keep out of reach of children. Contains nuts (macadamia nut). Known Adverse Reactions: Stop use if hypersensitivity occurs. Refrigerate after opening.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Fiche produit
- Chardon-Marie (Silybum marianum) graine, extrait 40:1, 50% silymarine par 1 cuillère à thé (5 mL)125 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Noix de macadamia, huile de tournesol, phosphatidylcholine, arôme de caramel naturel, extrait de noix de coco naturel, extrait de vanille biologique, glycérine, acide citrique, d-alpha tocophérol, eau purifiée. Contient des noix.
Usage ou fins recommandés : Le chardon-Marie (Silybum marianum) est utilisé en phytothérapie pour appuyer les fonctions hépatiques.
Posologie recommandée (adultes) : Prendre une (1) cuillère à thé (5 mL), deux (2) fois par jour, ou selon les directives d'un praticien de soins de santé. Peut être pris directement ou mélangé dans un verre d'eau. Durée d'utilisation : Utiliser pendant au moins trois (3) semaines pour constater les effets bénéfiques. Agiter avant usage. Réfrigérer après ouverture.
Mises en garde et précautions : Comme pour tout produit de santé naturel, consultez un praticien de soins de santé avant l'usage, particulièrement si vous êtes enceinte ou si les symptômes persistent ou s'aggravent. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants. Contient des noix (noix de macadamia). Réactions indésirables connues : Cesser l'utilisation si une hypersensibilité se manifeste. Réfrigérer après ouverture.
NPN 80120059
Support your liver with easy liquid milk thistle
Get CanPrev Liposomal Milk Thistle on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Liposomal Milk Thistle
125mg of liposomal milk thistle per serving, in an easy coconut caramel nut flavoured liquid - premium CanPrev quality.
Liposomal absorption technology
A bio-friendly phospholipid liposome is formulated to protect milk thistle extract in transit and support rapid, sustained cellular uptake.
A real, licensed liver-function claim
NPN 80120059 authorizes this product as used in Herbal Medicine to help support liver function.
No capsules, no bitterness
A smooth, coconut caramel nut flavoured liquid format - just one teaspoon, twice a day, with no capsules to swallow.
Vegan, clean-label brand
CanPrev - vegan, non-GMO, gluten-free formula, made without artificial colours, flavours or preservatives. NPN 80120059.
How to use it
Shake well before use
Shake the bottle well before every use to ensure the liposomal suspension is evenly mixed.
Take 1 teaspoon (5 mL), twice daily
Adults: take one (1) teaspoon (5 mL), two (2) times per day, or as directed by a health care practitioner. Can be taken directly or mixed into a glass of water.
Stay consistent
Use this product for at least three (3) weeks to see the beneficial effects on liver function.
Refrigerate after opening
Keep refrigerated once opened to help preserve freshness. Consult a health care practitioner before use if pregnant, or if symptoms persist or worsen.
What the research says about Milk Thistle and Silymarin
Educational summaries of published research on milk thistle and its active compound silymarin generally, and on liposomal delivery technology; not product-specific claims. CanPrev Liposomal Milk Thistle's own authorized use under NPN 80120059 is that it is used in Herbal Medicine to help support liver function.
Improved liver enzymes and histology in a phytosome RCT
In a 12-month randomized controlled trial of 179 patients with biopsy-confirmed NAFLD, a silybin-phosphatidylcholine-vitamin E complex significantly improved liver enzyme levels, insulin resistance (HOMA) and liver histology compared with placebo.
Human RCTA dedicated NASH trial found improved fibrosis scores
In a randomized, double-blind, placebo-controlled trial of biopsy-proven NASH patients, silymarin 700 mg three times daily for 48 weeks was associated with improvement in liver fibrosis compared with placebo.
Human RCTA meta-analysis found lower ALT and AST
Pooling 8 randomized controlled trials (587 patients) with NAFLD, silymarin reduced AST and ALT levels significantly more than control.
Meta-analysisImproved 4-year survival in one randomized trial
In a double-blind, randomized trial of 170 patients with cirrhosis, silymarin 140 mg three times daily was linked to a higher 4-year survival rate than placebo (58% vs 39%), with the strongest effect in alcoholic cirrhosis and less-advanced (Child A) disease.
Human RCTA larger trial found no survival benefit
A separate double-blind, randomized, multicenter trial of 200 patients with alcoholic cirrhosis found that silymarin 450 mg/day had no significant effect on survival or clinical course compared with placebo - a reminder that results vary by study.
Human RCTA Cochrane review found no significant effect on mortality
A systematic review of 13 randomized trials (915 participants) with alcoholic and/or viral hepatitis B or C liver disease found milk thistle had no significant effect on mortality, and was not associated with an increased risk of adverse events.
Cochrane systematic reviewA foundational biochemical mechanism review
A classic biochemical review describes silymarin and silibinin acting as antioxidants and free-radical scavengers, stabilizers of hepatocyte cell membranes, and stimulators of ribosomal RNA synthesis to support liver-cell protein production.
ReviewFour proposed protective mechanisms
A pharmacology review describes silymarin acting through four main mechanisms: antioxidant/glutathione regulation, hepatocyte membrane stabilization limiting toxin entry, stimulation of liver-cell regeneration, and inhibition of the fibrosis-driving transformation of stellate cells.
ReviewA 2024 review of antioxidant therapy in chronic liver disease
A comprehensive review of silymarin as an antioxidant therapy in chronic liver disease summarizes its efficacy, safety and antioxidant mechanisms across published clinical trials and pre-clinical studies.
ReviewInhibits inflammatory signalling in liver cells
Laboratory research found a standardized silymarin extract inhibited T-cell inflammatory cytokines and hepatocyte NF-kappaB signalling, and dose-dependently inhibited hepatitis C virus infection in cell culture.
Laboratory studyA 2024 review maps silymarin's anti-inflammatory pathways
A review of silymarin's clinical anti-inflammatory effects describes it acting through the NF-kappaB, MAPK and JAK-STAT3 signalling pathways to reduce pro-inflammatory factors.
ReviewHigh-dose silymarin did not help in one hepatitis C trial
In the SyNCH trial - a randomized, placebo-controlled study of 154 patients with chronic hepatitis C who had not responded to interferon therapy - silymarin at up to 700 mg three times daily had no significant effect on liver enzymes or hepatitis C viral load versus placebo, underscoring that benefits seen for one liver condition don't automatically transfer to another.
Human RCTReduced anti-tuberculosis drug-induced liver injury
A meta-analysis of randomized controlled trials found prophylactic silymarin reduced the occurrence of anti-tuberculosis drug-induced liver injury and improved liver function tests in patients on TB treatment.
Meta-analysisFaster symptom resolution in acute hepatitis
A randomized controlled trial of 105 patients with acute viral hepatitis found silymarin was associated with minimally faster resolution of dark urine and jaundice compared with placebo, with no serious adverse events.
Human RCTA classic review of the antioxidant basis for hepatoprotection
An early review of milk thistle for liver disease describes silymarin's hepatoprotective activity as resting on its antioxidant, free-radical-scavenging and lipid-peroxidation-inhibiting properties, while noting that human trial evidence at the time was mixed.
ReviewLiposomes raised oral bioavailability 3.5-fold in an animal model
A liposomal silymarin formulation achieved roughly 3.5-fold higher oral bioavailability than a plain silymarin suspension, while also showing targeting toward hepatocytes and immune cells.
Animal studyLiposomes improved tissue distribution versus ethosomes
Comparing silymarin entrapped in liposomes versus ethosomes in free-moving rats, the liposomal formulation showed favourable pharmacokinetics and tissue distribution when tracked by LC-MS/MS.
Animal studyA review of formulation strategies for silymarin's poor bioavailability
A pharmaceutical review explains that silymarin suffers from low water solubility and poor intestinal absorption, and surveys nanostructured delivery strategies - including liposomes - being developed to improve its bioavailability.
ReviewA large review found a low, placebo-comparable rate of side effects
A systematic review covering over 30 clinical studies found silymarin produced a low incidence of adverse events, comparable to placebo, alongside a significant reduction in liver-related mortality versus placebo.
Systematic reviewWell tolerated at high doses in decompensated liver disease
A randomized controlled trial of high-dose silymarin in patients with decompensated liver disease reported the treatment was well tolerated over the study period.
Human RCTNo drug-related adverse events across ascending doses
A phase I ascending multiple-oral-dose study in patients with chronic hepatitis C gave silymarin doses up to 700 mg every 8 hours for 7 days and reported no drug-related adverse events, though it found silybin's pharmacokinetics become nonlinear at higher doses.
Human Phase I trialA patent review of bioavailability techniques
A review of patented approaches to improving silymarin's bioavailability - including complexation, solubilization and targeted/controlled delivery - notes that plain silymarin suffers from poor absorption and low oral bioavailability.
ReviewA phospholipid complex raised silybin bioavailability several-fold
A review of a silybin-phosphatidylcholine phytosome complex reports it achieves several-fold higher bioavailability than plain silymarin in published pharmacokinetic comparisons.
ReviewA self-microemulsifying formulation showed rapid, high absorption in people
A pharmacokinetic study of a silymarin self-microemulsifying drug delivery system (SMEDDS) soft capsule in 12 healthy volunteers found rapid absorption (peak plasma levels reached in under an hour) and high oral bioavailability.
Human pharmacokinetic studyFrequently asked questions
What is CanPrev Liposomal Milk Thistle and what does it do?
It's a 125 mg liquid dose of Milk Thistle (Silybum marianum seed, 40:1 extract, standardized to 50% silymarin) per teaspoon. It is used in Herbal Medicine to help support liver function.
How do I take it?
Adults take one (1) teaspoon (5 mL), two (2) times per day, or as directed by a qualified health care practitioner. Shake well before use, and refrigerate after opening. Use for at least 3 weeks to see beneficial effects.
What is silymarin?
Silymarin is milk thistle's main active compound - this product uses a 40:1 seed extract standardized to 50% silymarin, providing 125 mg per teaspoon.
Why liposomal instead of a capsule?
Plain milk thistle extract is poorly absorbed by the body. The liposomal format wraps it in a phospholipid bubble designed to protect it in transit and support faster, more sustained uptake into cells.
How long does one bottle last?
Each 225 mL bottle provides 45 teaspoon servings - at the recommended dose of two teaspoons daily, that's roughly a 22-day supply.
Is it vegan? Does it contain nuts?
Yes, it's vegan, non-GMO and gluten-free. It does contain nuts (macadamia nut oil is part of the liposomal base) - always check the label if you have a nut allergy.
Who should use caution, or not use it?
Consult a health care practitioner before use, especially if you are pregnant, or if symptoms persist or worsen. Stop use if hypersensitivity occurs. Keep out of reach of children and do not use if the safety seal is broken.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support your liver with easy liquid milk thistle
Get CanPrev Liposomal Milk Thistle on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80120059. Milk Thistle is used in Herbal Medicine to help support liver function. Use for at least 3 weeks to see beneficial effects. The research summaries below concern Milk Thistle and silymarin generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use, especially if you are pregnant or if symptoms persist or worsen. Contains nuts (macadamia). Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a health care practitioner before use, especially if you are pregnant or if symptoms persist or worsen. Do not use if the safety seal is broken. Keep out of reach of children. Contains nuts (macadamia nut). Known Adverse Reactions: Stop use if hypersensitivity occurs. Refrigerate after opening.
Indications
Recommended Use or Purpose: Milk Thistle (Silybum marianum) is used in Herbal Medicine to help support liver function.
Ingredients
Medicinal ingredient (per 1 teaspoon/5 mL): Milk Thistle (Silybum marianum) seed, 40:1 extract, standardized to 50% silymarin - 125 mg. Non-medicinal ingredients: Macadamia nut, sunflower oil, phosphatidylcholine, natural caramel flavour, natural coconut extract, organic vanilla extract, glycerin, citric acid, d-alpha tocopherol, purified water. Contains nuts. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults): Take one (1) teaspoon (5 mL), two (2) times per day, or as directed by a health care practitioner. Can be taken directly or mixed with a glass of water. Duration of Use: Use for at least three (3) weeks to see beneficial effects. Shake well before use. Refrigerate after opening.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.