CanPrev Liposomal Melatonin 1.5mg - Chocolate Brownie | 450mL Liquid
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 teaspoon (5 mL) at or before bedtime |
| Licensed Natural Health Product | NPN 80108872 |
| Quality Standards | Made in Canada |
| Country | Made in Canada |
About this item
- 1.5 MG LIPOSOMAL MELATONIN PER TEASPOON: Each 5 mL teaspoon of this Chocolate Brownie flavoured liquid delivers 1.5 mg of melatonin - take one teaspoon per day, at or before bedtime, or as directed by a healthcare practitioner.
- LIPOSOMAL DELIVERY FOR RAPID, SUSTAINED UPTAKE: A patented liposomal delivery system carries melatonin in bio-friendly phospholipid bilayers, protecting it in transit and supporting quick, sustained cellular uptake.
- HELPS RESET THE SLEEP-WAKE CYCLE: Helps to reset the body's sleep-wake cycle, an aspect of the circadian rhythm.
- HELPS WITH ALTERED SCHEDULES & JET LAG: Helps increase the total sleep time in people suffering from sleep restriction or an altered sleep schedule (shift-work), and helps prevent the effects of jet lag.
- HELPS REDUCE TIME TO FALL ASLEEP: Helps to reduce the time it takes to fall asleep for people who fall asleep slowly.
- CLEAN, VEGAN CHOCOLATE BROWNIE LIQUID: Vegan, non-GMO, soy-free phospholipids sourced from sunflower - free from gluten, dairy and artificial colours, flavours or preservatives. Contains tree nuts (macadamia). Formulated and made in Canada.
Product Description
Liposomal Melatonin - 1.5mg, Chocolate Brownie Liquid

A 1.5 mg dose of melatonin in a delicious Chocolate Brownie flavoured liquid, delivered using a patented liposomal delivery system for rapid, sustained uptake. Bio-friendly phospholipid bilayers protect the melatonin in transit from digestive and enzymatic breakdown, supporting quick, sustained cellular uptake. Helps reset the body's sleep-wake cycle, helps increase total sleep time in people with sleep restriction or an altered sleep schedule (such as shift-work), helps prevent the effects of jet lag, and helps reduce the time it takes to fall asleep for people who fall asleep slowly. Licensed Natural Health Product NPN 80108872.
Une dose de 1,5 mg de mélatonine dans un délicieux liquide saveur brownie au chocolat, offerte grâce à un système de livraison liposomal breveté pour une absorption rapide et soutenue. Des bicouches phospholipidiques biocompatibles protègent la mélatonine en transit contre la dégradation digestive et enzymatique, favorisant une absorption cellulaire rapide et soutenue. Aide à réinitialiser le cycle éveil-sommeil du corps, aide à augmenter la durée totale du sommeil chez les personnes souffrant de restriction du sommeil ou d'horaire altéré (comme le travail à horaires variables), aide à prévenir les effets du décalage horaire, et aide à réduire le temps nécessaire pour s'endormir chez les personnes qui s'endorment lentement. Produit de santé naturel homologué. NPN 80108872.
Liposomal Delivery, Rapid & Sustained Uptake
1.5mg Melatonin per Teaspoon - Vegan · Non-GMO · Soy-Free Phospholipids · Made in Canada
1.5mg Melatonin, Liposomal Liquid Format
A precise 1.5 mg dose of melatonin in every 5 mL teaspoon of Chocolate Brownie flavoured liquid - one spoonful at or before bedtime.
Patented Liposomal Delivery System
Bio-friendly phospholipid bilayers protect melatonin from digestive and enzymatic breakdown in transit, supporting rapid, sustained cellular uptake.
What Liposomal Melatonin Supports
A single, precisely dosed liposomal active studied across sleep onset, circadian rhythm and jet lag research - here is what CanPrev Liposomal Melatonin is formulated to support.
Helps Reset the Sleep-Wake Cycle
Helps to reset the body's sleep-wake cycle, an aspect of the circadian rhythm.
Helps Increase Total Sleep Time
Helps increase the total sleep time in people suffering from sleep restriction or an altered sleep schedule, such as shift-work.
Helps Prevent the Effects of Jet Lag
Helps prevent the effects of jet lag when taken at bedtime while travelling and at your destination.
Helps Reduce Time to Fall Asleep
Helps to reduce the time it takes to fall asleep for people who fall asleep slowly.
Rapid & Sustained Liposomal Uptake
A patented liposomal delivery system protects melatonin in transit and supports quick, sustained cellular absorption.
Clean, Vegan Chocolate Brownie Liquid
Vegan, non-GMO, soy-free phospholipids, no artificial colours, flavours or preservatives - formulated and made in Canada.
CanPrev Liposomal Melatonin: Supplement Facts
Medicinal Ingredient (each 5 mL teaspoon contains):
- Melatonin liposomal1.5 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Natural chocolate flavour, cocoa powder, macadamia nut, sunflower oil, phosphatidylcholine, glycerin, d-alpha tocopherol, purified water. Contains tree nuts (macadamia).
Recommended Use or Purpose: Helps to reset the body's sleep-wake cycle. Helps increase the total sleep time in people suffering from sleep restriction or altered sleep schedule (shift-work) and helps prevent the effects of jet lag. Helps to reduce the time it takes to fall asleep for people who fall asleep slowly.
Recommended Dose (Adults): Take one (1) teaspoon (5 mL) per day, at or before bedtime, or as directed by a healthcare practitioner. For jet lag: take once a day at bedtime, while travelling, and at destination until adapted to the new time zone or daily pattern. Shake before use. Refrigerate after opening.
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use of this product especially if you are taking medications to suppress the immune system (immunosuppressive medications) or to affect mental state or increase sedation, steroids or blood thinners, or if you have cardiovascular, immune, liver or chronic kidney disease. Consult a health care practitioner prior to use if you are taking medications for seizures or blood pressure, or if you have a hormonal disorder, epileptic disorders, asthma, depression, diabetes, low blood sugar, or migraines. Consult a health care practitioner if symptoms persist or worsen, or if sleeplessness persists continually for more than 4 weeks (chronic insomnia). Do not use if you are pregnant or breastfeeding. Avoid taking with alcohol or products that increase drowsiness. Do not use if the safety seal is broken. Keep out of reach of children. Contains tree nuts (macadamia) - do not use if allergic to tree nuts. Known adverse reactions: some people may experience drowsiness - exercise caution if operating heavy machinery, driving a motor vehicle, or involved in activities requiring mental alertness. Do not drive or operate machinery for 5 hours after taking melatonin. Stop use if hypersensitivity/allergy occurs, or if you experience headache, confusion, or nausea.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Ingrédient médicinal (chaque cuillère à thé de 5 mL contient) :
- Mélatonine liposomale1.5 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Arôme naturel de chocolat, poudre de cacao, noix de macadamia, huile de tournesol, phosphatidylcholine, glycérine, d-alpha tocophérol, eau purifiée. Contient des noix (macadamia).
Usage ou fins recommandés : Aide à réinitialiser le cycle éveil-sommeil du corps. Aide à augmenter la durée totale du sommeil chez les personnes souffrant de restriction du sommeil ou d'horaire altéré du sommeil (travail à horaires variables) et aide à prévenir les effets du décalage horaire. Aide à réduire le temps nécessaire pour s'endormir chez les personnes qui s'endorment lentement.
Dose recommandée (adultes) : Prendre une (1) cuillère à thé (5 mL) par jour, à l'heure du coucher ou avant, ou selon l'avis d'un praticien de soins de santé. Pour le décalage horaire : prendre une fois par jour au coucher, durant le voyage, et à destination jusqu'à l'adaptation au nouveau fuseau horaire ou cycle. Agiter avant utilisation. Réfrigérer après ouverture.
Mises en garde et avertissements : Comme avec tout produit de santé naturel, consultez un praticien de soins de santé avant l'usage de ce produit surtout si vous prenez des médicaments pour inhiber le système immunitaire (immunosuppresseurs), qui affectent l'état mental ou augmentent la sédation, des stéroïdes ou des anticoagulants, ou si vous souffrez d'une maladie cardiovasculaire, immunitaire, du foie ou chronique des reins. Consultez un praticien de soins de santé avant l'usage si vous prenez des médicaments pour les convulsions ou la pression artérielle, ou si vous souffrez d'un problème hormonal, de troubles épileptiques, d'asthme, de dépression, de diabète, de bas taux de sucre, ou de migraines. Consultez un praticien de soins de santé si les symptômes persistent ou s'aggravent, ou si l'insomnie persiste sur une base continuelle au-delà de 4 semaines (insomnie chronique). Ne pas utiliser si vous êtes enceinte ou si vous allaitez. Éviter la prise avec de l'alcool ou des produits qui augmentent la somnolence. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants. Contient des noix (macadamia) - ne pas utiliser en cas d'allergie aux noix. Réactions indésirables connues : certaines personnes peuvent ressentir de la somnolence - faire preuve de prudence si vous opérez de la machinerie lourde, conduisez un véhicule motorisé, ou participez à une activité qui nécessite de la vigilance mentale. Ne pas conduire ou utiliser de machinerie pendant 5 heures après la prise de mélatonine. Cesser l'utilisation si une hypersensibilité/allergie se manifeste, ou si vous éprouvez des maux de tête, de la confusion, ou des nausées.
NPN 80108872
Reset your sleep cycle with a spoonful before bed
Get CanPrev Liposomal Melatonin on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Liposomal Melatonin
1.5 mg of melatonin per teaspoon, delivered in a patented liposomal liquid for rapid, sustained uptake - Chocolate Brownie flavour.
1.5mg Melatonin, Liposomal Liquid
Each 5 mL teaspoon delivers 1.5 mg of melatonin in a liposomal liquid format - no capsules to swallow, just one spoonful before bed.
Rapid & Sustained Uptake
A patented liposomal delivery system shields melatonin in phospholipid bilayers, protecting it from digestive breakdown and supporting quick, sustained cellular absorption.
Helps With Jet Lag & Shift Work
Helps increase total sleep time in people with sleep restriction or an altered sleep schedule, and helps prevent the effects of jet lag.
Premium Canadian Brand
CanPrev - formulated and made in Canada. NPN 80108872.
Inside every teaspoon
1.5 mg of liposomal melatonin in a Chocolate Brownie flavoured liquid - one teaspoon (5 mL), taken at or before bedtime.
How to use it
Shake, then take one teaspoon
Shake before use. Adults: take one (1) teaspoon (5 mL) per day, at or before bedtime, or as directed by a healthcare practitioner.
For jet lag
Take once a day at bedtime, while travelling, and at your destination, until adapted to the new time zone or daily pattern.
Refrigerate after opening
Keep the bottle refrigerated once opened to help preserve the liquid liposomal formula.
Avoid driving after taking melatonin
Do not drive or operate machinery for 5 hours after taking melatonin.
What the research says about melatonin and liposomal delivery
Educational summaries of published research on melatonin generally and on liposomal delivery technology generally; not product-specific claims. CanPrev Liposomal Melatonin's own claim is the use authorized under NPN 80108872.
Meta-analysis finds melatonin's most convincing evidence is for reducing sleep onset latency
A meta-analysis of randomized, controlled studies found the most convincing evidence for exogenous melatonin was in reducing sleep onset latency in primary insomnia and delayed sleep phase syndrome, compared with placebo.
Meta-AnalysisDose-finding RCT: melatonin reduced sleep onset latency by 35 minutes in children
A randomized, placebo-controlled, double-blind trial in 72 children with chronic sleep onset insomnia found that melatonin significantly advanced sleep onset and dim light melatonin onset by about 1 hour and decreased sleep onset latency by 35 minutes.
Human RCTRCT: oral melatonin reduced sleep onset latency and increased total sleep time in children with cerebral palsy
A randomized, double-blind, placebo-controlled trial in 120 children with cerebral palsy and sleep problems found that oral melatonin (3 to 10 mg) significantly reduced sleep onset latency and increased total sleep time over 12 weeks, with minimal side effects.
Human RCTMeta-analysis: melatonin improved sleep quality in adults undergoing hemodialysis
A systematic review and meta-analysis of 5 randomized trials (323 patients) found that melatonin improved global sleep quality scores, sleep duration and sleep efficiency compared with placebo in adults receiving hemodialysis.
Meta-AnalysisRCT: melatonin improved sleep quality and depth in schizophrenic outpatients with insomnia, without morning hangover
A double-blind, placebo-controlled study in 40 stable schizophrenic outpatients found that melatonin significantly improved the quality and depth of nighttime sleep, reduced nighttime awakenings and increased sleep duration, without producing a morning hangover.
Human RCTMeta-analysis found melatonin did not significantly change postoperative sleep quality after joint replacement
A systematic review and meta-analysis of 4 randomized trials (455 patients) found that melatonin did not significantly improve subjective or objective postoperative sleep quality following total joint arthroplasty - an honest null result for that specific surgical population.
Meta-AnalysisReview links occupational burnout to suppressed melatonin and circadian misalignment
A systematic review of 14 studies in healthcare professionals found burnout was associated with suppressed melatonin secretion, cortisol dysregulation and circadian misalignment, and noted that melatonin supplementation to improve sleep quality may help mitigate this occupational circadian disruption.
Systematic ReviewSystematic review: melatonin supplementation helps realign circadian rhythms disrupted by travel
A systematic review of 23 studies on circadian disruption from trans-meridian travel and shift work found that interventions including melatonin supplementation, personalized light exposure and chrono-modulation significantly improved sleep quality and reduced jet lag symptoms.
Systematic ReviewDim light melatonin onset can model circadian phase in later-life adults using wearable data
A validation study in adults aged 58 to 86 found that mathematical models using actigraphy and light-exposure data could predict ground-truth dim light melatonin onset with mean errors of about 1.4 hours or less, supporting melatonin's use as a real-world circadian marker.
Human StudyCochrane review: melatonin is remarkably effective at preventing and reducing jet lag
A Cochrane systematic review of 10 randomized trials in air travellers found that melatonin, taken close to the target bedtime, decreased jet lag from flights crossing five or more time zones in 9 of 10 trials, with daily doses between 0.5 and 5 mg similarly effective and a low incidence of other side effects.
Cochrane ReviewSystematic review confirms melatonin as an effective, low-side-effect option for jet lag
A systematic review of interventions for jet lag in air travellers found melatonin among the treatments with evidence of effectiveness and safety for minimizing jet lag symptoms after crossing multiple time zones.
Systematic ReviewSurvey of airline crew links shift work and circadian disruption to frequent melatonin use
A cross-sectional survey of 101 airline pilots and cabin crew found sleep disturbances in 71% and fatigue in 89% of respondents, with frequent melatonin use reported as a behavioral adaptation to circadian misalignment from shift work and time-zone crossing.
Human StudyReview: melatonin is a multifunctional free radical scavenger active in the mitochondria
A review of melatonin's cellular biology describes it as a multifunctional free radical scavenger, noting that melatonin concentrations are reportedly higher in mitochondria than in other cellular compartments, positioning it to help preserve mitochondrial redox homeostasis.
ReviewReview: melatonin acts as an antioxidant shield against lipid peroxidation
A review of melatonin's antioxidant chemistry describes how its amphiphilic nature allows it to access both lipid and aqueous cellular compartments, acting as both a direct free radical scavenger and an indirect regulator of antioxidant enzymes to counteract lipid peroxidation.
ReviewReview: melatonin's free radical scavenging and anti-inflammatory actions show atheroprotective potential
A review of melatonin's cardiovascular effects found that its direct free radical scavenger activity, indirect antioxidant qualities and anti-inflammatory capabilities contribute to protective effects against atherosclerosis-related pathogenic pathways.
ReviewMeta-analysis finds a good overall safety profile for higher-dose melatonin
A systematic review and meta-analysis of 79 randomized trials (3,861 adult participants) found that higher-dose melatonin (10 mg or more) did not increase serious adverse events or study withdrawals compared with placebo, though it modestly increased milder effects such as drowsiness, headache and dizziness.
Meta-AnalysisRCT: melatonin was well tolerated with no significant adverse effects as an adjunct therapy
A randomized, double-blind, placebo-controlled trial in 46 patients found that adjunctive melatonin (3 mg nightly) was well tolerated with no significant adverse effects and no hemodynamic instability observed during treatment.
Human RCTReview: melatonin does not cause hangover, withdrawal effects or addictive potential
A pharmacological review of melatonergic compounds notes that, compared with commonly prescribed sleep medications such as benzodiazepines, melatonin does not cause hangover or withdrawal effects and is devoid of any addictive potential.
ReviewRCT: a next-generation liposomal CoQ10 formulation increased absorption 4.3-fold over conventional CoQ10
A randomized, open-label, crossover study in healthy volunteers found that a liposomal CoQ10 formulation, built with phospholipid bilayers reinforced by gum arabic nanospheres, produced a 4.3-fold increase in AUC and markedly enhanced oral bioavailability compared with conventional CoQ10.
Human RCTRCT: liposomal delivery significantly enhanced CoQ10 absorption over standard CoQ10
A randomized, double-blind, placebo-controlled crossover study in 18 adults found that a liposomal CoQ10 formulation produced significantly higher peak plasma concentration (+31.3%) and total absorption (+22.6%) compared with standard, unformulated CoQ10.
Human RCTRCT: a surface-engineered liposomal formulation boosted vitamin C oral bioavailability more than 7-fold
A randomized, double-blinded, crossover study in 14 healthy volunteers found that a surface-engineered liposomal calcium ascorbate formulation achieved more than a 7-fold enhancement in oral bioavailability compared with the unformulated nutrient at an equivalent dose.
Human RCTStudy: encapsulating melatonin in liposomes improved its delivery and permeation
A formulation study found that melatonin encapsulated in elastic liposomes achieved high encapsulation efficiency (73.91%) with the chemical structure of melatonin unchanged after preparation, and showed 1.5 times higher cumulative penetration than conventional liposomes.
Laboratory StudyReview: nanoliposomal delivery protects nutrients and improves trans-epithelial transport
A review of nanoliposomal nutrient delivery found that encapsulation within phosphatidylcholine-rich bilayers consistently enhanced nutrient stability in simulated gastric fluid and improved trans-epithelial transport two-fold to ten-fold compared with free-compound controls.
ReviewReview: liposomal and other nanocarrier systems address nutrients' natural bioavailability limits
A review of nanoparticle-based delivery systems found that liposomes and related lipid nanocarriers can improve nutrient solubility, protect against enzymatic degradation, and facilitate targeted transport compared with traditional oral formulations.
ReviewFrequently asked questions
What is CanPrev Liposomal Melatonin and what does it do?
It's a 1.5 mg melatonin liquid in a Chocolate Brownie flavour, delivered using a liposomal delivery system for rapid, sustained uptake. It helps reset the body's sleep-wake cycle, helps increase total sleep time in people with sleep restriction or an altered sleep schedule (such as shift-work), helps prevent the effects of jet lag, and helps reduce the time it takes to fall asleep for people who fall asleep slowly.
How do I take it?
Shake before use. Adults take one (1) teaspoon (5 mL) per day, at or before bedtime, or as directed by a healthcare practitioner.
What does "liposomal" mean?
The melatonin is carried inside bio-friendly phospholipid bilayers (liposomes), which protect it from digestive and enzymatic breakdown in transit and support quick, sustained uptake at the cellular level.
How many servings are in a bottle?
Each 450 mL bottle provides up to 90 servings at the 1-teaspoon (5 mL) dose.
What's in each teaspoon?
Melatonin 1.5 mg. Non-medicinal ingredients: natural chocolate flavour, cocoa powder, macadamia nut, sunflower oil, phosphatidylcholine, glycerin, d-alpha tocopherol, purified water. Contains tree nuts (macadamia).
Can I use it for jet lag?
Yes - for jet lag, take once a day at bedtime while travelling and at your destination, until you've adapted to the new time zone.
Will it affect my ability to drive the next morning?
Do not drive or operate machinery for 5 hours after taking melatonin - take it only when you are able to go to bed.
Can I take it if I'm pregnant, breastfeeding, or have a health condition?
Do not use if you are pregnant or breastfeeding. Consult a healthcare practitioner before use if you are taking medications that suppress the immune system, affect mental state or increase sedation, steroids or blood thinners, medications for seizures or blood pressure, or if you have a hormonal disorder, epileptic disorders, asthma, depression, diabetes, low blood sugar, migraines, or cardiovascular, immune, liver or chronic kidney disease.
Is it safe to use long-term?
Consult a healthcare practitioner if symptoms persist or worsen, or if sleeplessness persists continually for more than 4 weeks (chronic insomnia).
Does it contain allergens?
Yes - this liquid contains tree nuts (macadamia). It is vegan, non-GMO, and free from gluten, dairy, artificial colours, flavours and preservatives, but is not nut-free.
Is CanPrev Liposomal Melatonin made in Canada?
Yes. It's formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed by Health Canada under NPN 80108872.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Reset your sleep cycle with a spoonful before bed
Get CanPrev Liposomal Melatonin on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80108872. Helps to reset the body's sleep-wake cycle. Helps increase the total sleep time in people suffering from sleep restriction or altered sleep schedule (shift-work) and prevents the effects of jet lag. Helps to reduce the time it takes to fall asleep for people who fall asleep slowly. The research summaries below concern melatonin and liposomal delivery technology generally and are educational - they are not claims about this finished product. Read and follow the label. Contains tree nuts (macadamia). Do not use if you are pregnant or breastfeeding. Do not drive or operate machinery for 5 hours after taking melatonin. Consult a health care practitioner before use if you are taking certain medications or have certain health conditions (see label), and for use beyond 4 weeks. Do not use if the safety seal is broken. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a health care practitioner prior to use of this product especially if you are taking medications to suppress the immune system (immunosuppressive medications) or to affect mental state or increase sedation, steroids or blood thinners, or if you have cardiovascular, immune, liver or chronic kidney disease. Consult a health care practitioner prior to use if you are taking medications for seizures or blood pressure, or if you have a hormonal disorder, epileptic disorders, asthma, depression, diabetes, low blood sugar, or migraines. Consult a health care practitioner if symptoms persist or worsen, or if sleeplessness persists continually for more than 4 weeks (chronic insomnia). Do not use if you are pregnant or breastfeeding. Avoid taking with alcohol or products that increase drowsiness. Do not use if the safety seal is broken. Keep out of reach of children. Contains tree nuts (macadamia) - do not use if allergic to tree nuts. Known adverse reactions: some people may experience drowsiness - exercise caution if operating heavy machinery, driving a motor vehicle, or involved in activities requiring mental alertness. Do not drive or operate machinery for 5 hours after taking melatonin. Stop use if hypersensitivity/allergy occurs, or if you experience headache, confusion, or nausea.
Indications
Recommended Use or Purpose: Helps to reset the body's sleep-wake cycle. Helps increase the total sleep time in people suffering from sleep restriction or altered sleep schedule (shift-work) and helps prevent the effects of jet lag. Helps to reduce the time it takes to fall asleep for people who fall asleep slowly.
Ingredients
Medicinal Ingredient (per 1 teaspoon/5 mL): Melatonin, liposomal, 1.5 mg. Non-medicinal ingredients: Natural chocolate flavour, cocoa powder, macadamia nut, sunflower oil, phosphatidylcholine, glycerin, d-alpha tocopherol, purified water. Contains tree nuts (macadamia). NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults): Take one (1) teaspoon (5 mL) per day, at or before bedtime, or as directed by a healthcare practitioner. For jet lag: take once a day at bedtime, while travelling, and at destination until adapted to the new time zone or daily pattern. Shake before use. Refrigerate after opening.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.







