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Health Canada NPN 80109975 300mg GABA + 100mg L-Theanine per Teaspoon Vegan · Non-GMO · Gluten-Free 225ml Liquid · 45 Servings · Citrus Flavour
Liposomal GABALiposomal GABA - benefits and key ingredients Liposomal GABA - lifestyleLiposomal GABA - ingredientsLiposomal GABA - supplement facts panel

CanPrev Liposomal GABA with L-Theanine - Relaxation | 225mL

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$42.99 CAD ($0.96 / serving)
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BrandCanPrev
Serving1 teaspoon (5ml)
Licensed Natural Health ProductNPN 80109975
Quality StandardsGMP-compliant facility
CountryMade in USA Made in USA

About this item

  • ENHANCED RELAXATION: A liposomal blend of 300mg GABA and 100mg L-Theanine per teaspoon, formulated to help you unwind after a demanding day - the Health Canada-authorized use of this product is to help temporarily promote relaxation.
  • EVENING WIND-DOWN ROUTINE: A citrus-flavoured liquid you can take as part of a calming evening routine, alongside good sleep habits.
  • GABA AND L-THEANINE, TOGETHER: GABA is the brain's main inhibitory neurotransmitter; L-theanine is a calming amino acid naturally found in tea leaves - this formula combines both in a single liposomal liquid.
  • FAST-ACTING LIPOSOMAL FORMULA: CanPrev's liposomal technology wraps GABA and L-theanine in bio-friendly, soy-free phospholipids sourced from sunflower, designed for rapid and sustained cellular uptake.
  • PLEASANT CITRUS LIQUID, NO CAPSULES: A natural lemon-and-orange-flavoured liquid taken by the teaspoon - no capsules to swallow, with no artificial colours, flavours or preservatives.
  • VEGAN, MADE WITHOUT FILLERS: Vegan, non-GMO, gluten-free, dairy-free and soy-free, with no artificial colours, flavours or preservatives - just GABA, L-theanine and the liposomal carrier.

Product Description

Liposomal GABA with L-Theanine - Fast-Acting Liquid Calm

CanPrev Liposomal GABA

CanPrev Liposomal GABA delivers 300mg of GABA plus 100mg of L-Theanine per teaspoon, carried in a soy-free, bio-friendly phospholipid liposomal system designed for rapid and sustained cellular uptake. A natural citrus-flavoured liquid - no capsules. Helps to temporarily promote relaxation. Licensed Natural Health Product, NPN 80109975. Licensed Natural Health Product NPN 80109975.

CanPrev GABA Liposomal offre 300 mg de GABA et 100 mg de L-Théanine par cuillère à thé, dans un système liposomal de phospholipides sans soya et bio-compatible, conçu pour une absorption cellulaire rapide et soutenue. Un liquide naturel aromatisé aux agrumes - sans capsules. Aide à promouvoir temporairement la relaxation. Produit de santé naturel homologué, NPN 80109975.

Liposomal GABA lifestyle
CanPrev Liposomal GABA
300mg GABA + 100mg L-Theanine · Liposomal Liquid

Two Calming Actives, One Liposomal Liquid

300mg GABA plus 100mg L-Theanine - Vegan, Non-GMO, Gluten-Free, Soy-Free Phospholipids

Liposomal Delivery, Not a Capsule

Bio-friendly phospholipid bilayers, sourced from sunflower rather than soy, are designed to protect GABA and L-theanine from digestive breakdown and support rapid, sustained cellular uptake.

GABA Paired With L-Theanine

300mg of GABA per teaspoon is paired with 100mg of L-theanine, a calming amino acid naturally found in tea leaves, in a single natural citrus-flavoured liquid.

Advanced Ingredients, Superior Results

GABA and L-theanine are two of the most studied calming compounds in nutrition science. Here's what's inside every teaspoon of CanPrev Liposomal GABA.

GABA (4-Aminobutanoic acid)

The brain's main inhibitory neurotransmitter, delivered here in a liposomal liquid format designed for rapid, sustained uptake.

300 mg per teaspoon (5ml)

L-Theanine

A calming amino acid naturally found in tea leaves, paired with GABA in this formula and studied for its association with alpha brain-wave activity linked to relaxed alertness.

100 mg per teaspoon (5ml)

CanPrev Liposomal GABA: Supplement Facts

CanPrev™Liposomal GABA
English

Medicinal Ingredients (per teaspoon, 5ml)

  • GABA (4-Aminobutanoic acid) per teaspoon300 mg
  • L-Theanine per teaspoon100 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Purified water, glycerin, sunflower oil, phosphatidylcholine, turmeric extract, acacia gum, vitamin E, citric acid, natural lemon flavour, natural orange flavour.

Recommended Use or Purpose: Helps to temporarily promote relaxation.

Recommended Dose (Adults 19 years and older): Take one (1) teaspoon (5ml) per day, or as directed by a health care practitioner. Recommended Duration of Use: For use beyond 4 weeks, consult a health care practitioner. Shake before use. Refrigerate after opening.

Cautions and Warnings: As with any natural health product, you should consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner if symptoms persist or worsen. Do not use if the safety seal is broken. Keep out of reach of children. Shake well before use. Refrigerate after opening.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Made in the USA for CanPrev Natural Health Products Ltd., Toronto, ON, Canada. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Ingrédients médicinaux (par cuillère à thé, 5 ml)

  • GABA (Acide 4-aminobutanoïque) par cuillère à thé300 mg
  • L-Théanine par cuillère à thé100 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Eau purifiée, glycérine, huile de tournesol, phosphatidylcholine, extrait de curcuma, gomme arabique, vitamine E, acide citrique, arôme naturel de citron, arôme naturel d'orange.

Usage ou fins recommandés : Aide à promouvoir temporairement la relaxation.

Posologie recommandée (adultes de 19 ans et plus) : Prendre une (1) cuillère à thé (5 ml) par jour, ou selon les directives d'un praticien de soins de santé. Durée d'utilisation recommandée : Consulter un praticien de soins de santé pour un usage de plus de 4 semaines. Agiter avant usage. Réfrigérer après ouverture.

Mises en garde et avertissements : Comme avec tout produit de santé naturel, vous devriez consulter un praticien de soins de santé avant l'usage si vous êtes enceinte ou allaitez. Consulter un praticien de soins de santé si les symptômes persistent ou s'aggravent. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants. Agiter avant utilisation. Réfrigérer après ouverture.

NPN 80109975

300mg GABA + 100mg L-Theanine per TeaspoonLiposomal Liquid · Natural Citrus Flavour225ml Bottle · 45 ServingsVegan · Non-GMO · Gluten-Free

Add CanPrev Liposomal GABA to your daily routine

Get CanPrev Liposomal GABA on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev Liposomal GABA

300mg GABA plus 100mg L-Theanine in a fast-acting, soy-free liposomal liquid - premium CanPrev quality.

Liposomal, not just liquid

Soy-free sunflower phospholipid bilayers are designed to protect GABA and L-theanine in transit and support rapid, sustained cellular uptake - not just a flavoured liquid version of a capsule.

Two calming actives together

300mg of GABA paired with 100mg of L-theanine per teaspoon - two of the most studied calming compounds in nutrition science, in one formula.

No capsules, natural citrus flavour

A pleasant citrus-flavoured liquid, taken by the teaspoon, with no artificial colours, flavours or preservatives.

Trusted Canadian brand

CanPrev - a licensed Natural Health Product, NPN 80109975.

Inside every teaspoon

300mg of GABA plus 100mg of L-Theanine in a soy-free, phospholipid liposomal delivery, natural citrus-flavoured liquid.

GABA (4-Aminobutanoic acid) 300 mg per teaspoon (5ml)L-Theanine 100 mg per teaspoon (5ml)

How to use it

Shake well before use

Shake the bottle well before each use to ensure the liposomal liquid is evenly mixed.

Take 1 teaspoon (5ml) per day

Adults (19 years and older): take one (1) teaspoon per day, or as directed by a health care practitioner.

Refrigerate after opening

Store in a cool, dry place before opening; refrigerate the bottle once opened.

Consult a practitioner for use beyond 4 weeks

Consult a health care practitioner before using for longer than 4 weeks, or if you are pregnant, breastfeeding, or have other health considerations.

What the research says about GABA, L-theanine and liposomal delivery

Educational summaries of published research on GABA, L-theanine, and liposomal/phospholipid delivery technology - including a real, ongoing scientific debate about how oral GABA acts in the body; these are not product-specific claims. CanPrev Liposomal GABA's own claim is the authorized use under NPN 80109975: helping to temporarily promote relaxation.

GABA & Relaxation (the Authorized Use)

Oral GABA increased relaxation-linked brain waves within an hour

In a human study, volunteers who took oral GABA showed a significant increase in alpha brain waves and a decrease in beta waves compared with water or L-theanine, changes the researchers linked to relaxation and reduced anxiety within about 60 minutes.

Human study
Abdou et al., BioFactors (2006)
GABA & Relaxation (the Authorized Use)

Eased the EEG and mood changes of a mental-stress task

In a randomized, placebo-controlled crossover trial, a single 100 mg dose of oral GABA reduced the alpha- and beta-wave EEG changes and mood-scale shifts normally triggered by a mental-arithmetic stress task, compared with placebo.

Human RCT
Yoto et al., Amino Acids (2011)
GABA & Relaxation (the Authorized Use)

GABA and theanine named among supplements studied for relaxation

A review of dietary supplements used for relaxation and anxiolytic effects lists GABA and theanine, alongside botanicals like valerian and lemon balm, among ingredients reported to promote relaxation, generally by boosting GABA activity or acting as GABA-receptor agonists.

Review
Weeks, Medical Science Monitor (2009)
L-Theanine & Calm, Focused Attention

L-theanine shifted brain activity toward relaxed alertness

A study measuring oscillatory alpha-band brain activity found L-theanine, taken alone or with caffeine, altered background and task-related visual attention processing - a marker linked to a calm, alert mental state, distinct from caffeine's effects taken alone.

Human study
Kelly et al., Journal of Nutrition (2008)
L-Theanine & Calm, Focused Attention

Combined with caffeine, L-theanine sharpened performance and alertness

In a randomized trial, a combination of L-theanine and caffeine improved accuracy on a task-switching test and increased self-reported alertness while reducing tiredness, compared with placebo - an effect attributable to the combination, not L-theanine alone.

Human RCT
Giesbrecht et al., Nutritional Neuroscience (2010)
L-Theanine & Calm, Focused Attention

31-trial meta-analysis: a single dose measurably sharpens attention

A systematic review and meta-analysis of 31 randomized trials (1,168 participants) found a single 200 mg dose of L-theanine, taken 30 to 60 minutes beforehand, significantly improved choice reaction time, with no serious adverse events reported across the pooled trials.

Meta-analysis
Gerolymos et al., Molecular Psychiatry (2026)
GABA + L-Theanine Combination Research

Combined GABA and L-theanine improved sleep scores over 4 weeks

In an exploratory study, adults with sleep problems who took a combined 700 mg GABA and 200 mg L-theanine daily for 4 weeks saw their total Pittsburgh Sleep Quality Index score improve significantly, from 9.42 to 6.26 on average - though the single-arm design means the finding needs confirmation against a placebo group.

Exploratory study
Konno et al., European Review for Medical and Pharmacological Sciences (2026)
GABA + L-Theanine Combination Research

A GABA/L-theanine mixture shortened sleep latency in animal models

In mice and rats, a combined GABA and L-theanine mixture reduced the time it took to fall asleep and improved non-REM sleep on EEG recordings, with gene-expression testing suggesting the combination's sleep-promoting effect involves transcriptional changes.

Animal study
Kim et al., Pharmaceutical Biology (2019)
GABA + L-Theanine Combination Research

An L-theanine-based drink eased stress markers and shifted brain waves

A randomized, placebo-controlled crossover trial found an L-theanine-based nutrient drink reduced subjective and cortisol stress responses to a cognitive stressor, with the calming effect confirmed by magnetoencephalography brain-wave measurements.

Human RCT
White et al., Nutrients (2016)
Liposomal & Phospholipid Delivery Technology

Phosphatidylcholine liposomes improved oral bioavailability in a rat model

A liposome-encapsulated formulation made with soy lecithin phosphatidylcholine achieved 68% encapsulation efficiency and produced better absorption pharmacokinetics after oral dosing in rats, compared with unencapsulated or plain-lecithin-mixed forms of the same active.

Animal study
Takahashi et al., Journal of Agricultural and Food Chemistry (2009)
Liposomal & Phospholipid Delivery Technology

A protective coating extended a liposome's stability in the gut

Coating liposomes carrying a bioactive peptide with sodium alginate increased their particle stability, storage life, and simulated gastrointestinal stability by about 50%, illustrating how liposome engineering is used to help protect actives on their way through digestion.

Lab study
Wu et al., Food Chemistry (2023)
Liposomal & Phospholipid Delivery Technology

Delivery-system choice measurably changes supplement absorption

A comparative lab study of six iron dietary supplements using different delivery technologies - including microencapsulation and liposomes - found the delivery system itself changed the speed and pattern of intestinal iron absorption, underscoring why formulation technology matters alongside the raw ingredient dose.

Lab study
Pastore et al., Molecules (2020)
Sleep Quality Research

L-theanine improved sleep quality scores over 4 weeks

In a randomized, placebo-controlled crossover trial, healthy adults taking 200 mg of L-theanine daily for 4 weeks saw their Pittsburgh Sleep Quality Index scores improve, with specific gains in sleep latency, sleep disturbance and less reliance on sleep aids, versus placebo.

Human RCT
Hidese et al., Nutrients (2019)
Sleep Quality Research

GABA improved sleep efficiency over 90 days

In a randomized, placebo-controlled trial, sedentary women with overweight or obesity taking 200 mg of GABA daily for 90 days alongside physical exercise showed improved habitual sleep efficiency and lower Pittsburgh Sleep Quality Index scores, plus reduced depression scores, versus placebo.

Human RCT
Guimarães et al., Journal of Dietary Supplements (2024)
Sleep Quality Research

Sleep quality tracked as a secondary measure in a 95-day GABA trial

A 95-day randomized trial of oral GABA (500 mg, three times daily) in adults included self-reported sleep quality among its secondary measures, one example of sleep being actively studied as an outcome of interest for oral GABA.

Human RCT
de Bie et al., American Journal of Clinical Nutrition (2023)
Stress-Response Research

L-theanine and L-tyrosine were tested in a high-pressure stress drill

In a randomized trial using a virtual-reality active-shooter training drill and cognitive stress tasks, participants given L-theanine or L-tyrosine (tested as separate treatment arms) showed changes in stress biomarkers and cognitive performance compared with placebo.

Human RCT
McAllister et al., Stress (2024)
Stress-Response Research

Theanine mitigated the stress response that caffeine accentuated

In a double-blind, repeated-measures trial, caffeine and theanine had opposite effects on visual attention under emotional arousal: caffeine accentuated felt and physiological (cortisol) stress responses to arousing content, while theanine mitigated them.

Human study
Giles et al., Canadian Journal of Physiology and Pharmacology (2017)
Stress-Response Research

GABA supported an immune stress marker during a real-world stressor

In a second experiment from the same research group, acrophobic volunteers crossing a suspended bridge as a stress test showed a marked drop in salivary immunoglobulin A (an immune stress marker) in the placebo group, while the GABA group's levels stayed significantly higher.

Human study
Abdou et al., BioFactors (2006)
Why Pair GABA with L-Theanine: the Blood-Brain-Barrier Question

A genuine, unresolved scientific debate

A widely cited review examines whether GABA consumed as a food supplement can meaningfully influence brain activity, given that GABA has long been thought unable to cross the blood-brain barrier in its free form - the authors conclude the mechanism is still far from clear and may instead run through the gut and enteric nervous system.

Review
Boonstra et al., Frontiers in Psychology (2015)
Why Pair GABA with L-Theanine: the Blood-Brain-Barrier Question

L-theanine, unlike GABA, is described as crossing the blood-brain barrier

A 2025 review of the L-theanine literature notes it is well absorbed from the intestine and can cross the blood-brain barrier, with some studies suggesting it increases alpha brain waves linked to relaxation and selective attention - a contrast the authors draw with GABA's more debated absorption route.

Review
Dashwood et al., Nutrition Research (2025)
Why Pair GABA with L-Theanine: the Blood-Brain-Barrier Question

GABA helps set the brake on the body's stress axis

A neuroscience review describes how GABA, glutamate and norepinephrine together regulate the corticotropin-releasing-hormone neurons that drive the hypothalamic-pituitary-adrenal (HPA) stress axis, with GABA supplying much of the inhibitory tone that keeps this system in check.

Review
Levy & Tasker, Frontiers in Cellular Neuroscience (2012)
Safety & Tolerability

A human dose-escalation trial found GABA well tolerated

Adults given oral GABA in a controlled-release formulation at 200 mg, 600 mg and 1200 mg over an 11-day dose-escalation trial experienced no serious adverse events, with only a few mild, transient effects reported.

Human study
Espes et al., BMJ Open Diabetes Research & Care (2021)
Safety & Tolerability

Monitored safely over 95 days at a higher daily GABA dose

A 95-day trial giving adults 500 mg of oral GABA three times daily monitored safety throughout; its primary glucose-control outcome was not significantly different from placebo, an honest reminder that not every studied outcome shows an effect.

Human RCT
de Bie et al., American Journal of Clinical Nutrition (2023)
Safety & Tolerability

No serious adverse events across 31 pooled L-theanine trials

A systematic review and meta-analysis pooling 31 randomized trials (1,168 participants) assessed dropout rates and reasons for L-theanine versus placebo and reported no serious adverse events, concluding L-theanine is safe alongside its short-term attention benefit.

Meta-analysis
Gerolymos et al., Molecular Psychiatry (2026)

Frequently asked questions

What is CanPrev Liposomal GABA and what does it do?

It's a liposomal liquid supplement providing 300mg of GABA and 100mg of L-theanine per teaspoon. Its Health Canada-authorized use is to help temporarily promote relaxation.

How do I take it?

Adults (19 years and older): take one (1) teaspoon (5ml) per day, or as directed by a health care practitioner. Shake well before use and refrigerate after opening. Consult a health care practitioner for use beyond 4 weeks.

What does 'liposomal' mean, and why does it matter?

CanPrev's liposomal technology wraps GABA and L-theanine in bio-friendly phospholipid bilayers - the same basic building blocks as cell membranes - sourced from sunflower rather than soy. This is designed to protect the actives from digestive and enzymatic breakdown in transit and support rapid, sustained cellular uptake, compared with a standard capsule or tablet.

Why does it include L-theanine alongside GABA?

L-theanine is a calming amino acid naturally found in tea leaves. It's included alongside GABA in this liposomal formula; general research on L-theanine has studied its association with alpha brain-wave activity linked to relaxed alertness.

Does oral GABA cross the blood-brain barrier?

This is a genuine, ongoing scientific question. GABA has limited ability to cross the blood-brain barrier in its free form, so researchers continue to study exactly how oral GABA produces its effects, including possible gut-brain-axis pathways. CanPrev Liposomal GABA's labelled claim (helping to temporarily promote relaxation) reflects its authorized use, not a specific mechanism claim.

Is it vegan and allergen-friendly?

Yes - vegan, non-GMO, gluten-free, dairy-free and soy-free, with no artificial colours, flavours or preservatives. The liposomal phospholipids are sourced from sunflower, not soy.

Who should not use it?

Do not use with alcohol. Consult a health care practitioner before use if you are pregnant or breastfeeding, or if symptoms persist or worsen. Do not use if the safety seal is broken. Keep out of reach of children.

How long does one bottle last?

Each 225ml bottle provides 45 teaspoon servings - a 45-day supply at the labelled adult dose of 1 teaspoon per day.

Where is it made?

CanPrev Liposomal GABA is made in the USA for CanPrev Natural Health Products Ltd. (Toronto, ON, Canada), and is a licensed Natural Health Product under NPN 80109975.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

300mg GABA + 100mg L-Theanine per TeaspoonLiposomal Liquid · Natural Citrus Flavour225ml Bottle · 45 ServingsVegan · Non-GMO · Gluten-Free

Add CanPrev Liposomal GABA to your daily routine

Get CanPrev Liposomal GABA on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80109975. Helps to temporarily promote relaxation. The research summaries below concern the ingredients GABA and L-theanine generally, and liposomal/phospholipid delivery technology broadly, and are educational - they are not claims about this finished product. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if symptoms persist or worsen. Do not use with alcohol. Read and follow the label. Results may vary.

Important information

Safety Information

Cautions and Warnings: As with any natural health product, you should consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner if symptoms persist or worsen. Do not use if the safety seal is broken. Keep out of reach of children. Shake well before use. Refrigerate after opening.

Indications

Recommended Use or Purpose: Helps to temporarily promote relaxation.

Ingredients

Medicinal Ingredients (1 teaspoon, 5ml): GABA (4-Aminobutanoic acid) 300 mg, L-Theanine 100 mg. Non-medicinal ingredients: Purified water, glycerin, sunflower oil, phosphatidylcholine, turmeric extract, acacia gum, vitamin E, citric acid, natural lemon flavour, natural orange flavour. Contraindications: Do not use with alcohol. Vegan, GMO-free, no gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives or animal products. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults 19 years and older): Take one (1) teaspoon (5ml) per day, or as directed by a health care practitioner. Recommended Duration of Use: For use beyond 4 weeks, consult a health care practitioner. Shake before use. Refrigerate after opening.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Made in the USA for CanPrev Natural Health Products Ltd., Toronto, ON, Canada. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.