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Health Canada NPN 80091468 5 g Pure L-Glycine per Scoop - Fermentation-Based Vegan / Non-GMO / Gluten-Free / Soy-Free Formulated & Made in Canada
L-Glycine Vegan Amino Acid PowderL-Glycine Vegan Amino Acid Powder - benefits and key ingredients L-Glycine Vegan Amino Acid Powder - lifestyleL-Glycine Vegan Amino Acid Powder - ingredientsL-Glycine Vegan Amino Acid Powder - supplement facts panel

CanPrev L-Glycine Vegan Amino Acid Powder | 450g

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BrandCanPrev
Serving1 scoop (5 g), up to 3 times daily, mixed in a cup of liquid
Licensed Natural Health ProductNPN 80091468
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • POWER THROUGH DEMANDING DAYS: CanPrev L-Glycine Vegan Amino Acid Powder delivers 5 g of pure L-Glycine per scoop, involved in muscle protein synthesis - supporting your active lifestyle and post-workout recovery.
  • WIND DOWN WITHOUT CHECKING OUT: Integrate this pure L-Glycine powder into your evening routine. As a stimulant-free amino acid that acts as an inhibitory neurotransmitter, it fits naturally into a calming daily wellness routine.
  • FUEL YOUR BODY WITH CONFIDENCE: CanPrev L-Glycine is a pure, single-ingredient, fermentation-based vegan amino acid powder - verified GMO-free, gluten-free, dairy-free and soy-free, with no fillers or binders.
  • SEAMLESSLY FIT INTO YOUR DAY: This unflavoured powder mixes easily into water, juice or your favourite smoothie - one 450 g container provides a 90-scoop supply.
  • MADE IN CANADA, LICENSED BY HEALTH CANADA: Formulated and made in Canada by CanPrev Natural Health Products Ltd. and licensed under NPN 80091468.

Customer Reviews

4.6 out of 5 · 273 global ratings
Read genuine reviews on Amazon →Available at Amazon

Product Description

L-Glycine Vegan Amino Acid Powder - 5 g Pure L-Glycine per Scoop

CanPrev L-Glycine Vegan Amino Acid Powder

CanPrev L-Glycine Vegan Amino Acid Powder is a pure, single-ingredient, fermentation-based amino acid supplement, delivering 5 g of L-Glycine in every scoop. Glycine is involved in muscle protein synthesis, making this unflavoured powder a simple daily addition for athletic support and workout recovery. Free of fillers, binders, artificial colours and sweeteners - just L-Glycine. Vegan and licensed as a Natural Health Product. Licensed Natural Health Product NPN 80091468.

La poudre d'acide aminé végane L-Glycine de CanPrev est un supplément d'acide aminé pur, à ingrédient unique, d'origine fermentaire, offrant 5 g de L-Glycine par mesure. La glycine participe à la synthèse des protéines musculaires, ce qui fait de cette poudre non aromatisée un ajout quotidien simple pour le soutien athlétique et la récupération à l'entraînement. Sans agents de remplissage, liants, colorants ou édulcorants artificiels - seulement de la L-Glycine. Végane et homologuée comme produit de santé naturel.

L-Glycine Vegan Amino Acid Powder lifestyle
CanPrev L-Glycine Vegan Amino Acid Powder
5 g Pure L-Glycine per Scoop - Fermentation-Based & Vegan

Built for Athletic Support and Daily Calm

5 g pure, fermentation-based L-Glycine per scoop - unflavoured, no fillers, up to 3 scoops daily

5 g of Pure L-Glycine per Scoop

Each scoop delivers 5 g of fermentation-based L-Glycine, involved in muscle protein synthesis - take 1 scoop, up to 3 times daily, or as directed by a healthcare practitioner.

Clean, Single-Ingredient Formula

No fillers, binders, artificial colours, flavours or sweeteners - just L-Glycine, mixing easily into water, juice or a smoothie.

Why This Formula

CanPrev L-Glycine is built around one real active - pure, fermentation-based L-Glycine - delivered in a flexible, unflavoured daily powder.

Athletic Support & Muscle Protein Synthesis

Glycine is involved in muscle protein synthesis - this product's Health Canada-authorized use as a workout supplement for athletic support.

5 g Pure L-Glycine per Scoop

Each scoop delivers a full 5 g dose of fermentation-based L-Glycine, with no non-medicinal ingredients.

Calming, Stimulant-Free Amino Acid

Glycine acts as an inhibitory neurotransmitter, fitting naturally into an evening wind-down routine without stimulant effects.

Vegan, Fermentation-Based & Clean-Label

GMO-free, gluten-free, dairy-free and soy-free, with no fillers, binders, artificial colours or sweeteners.

CanPrev L-Glycine Vegan Amino Acid Powder: Supplement Facts

CanPrev™L-Glycine Vegan Amino Acid Powder
English

Each scoop contains:

  • L-Glycine5 g

Non-Medicinal Ingredients: None.

Recommended Use or Purpose: Glycine (L-Glycine) is an amino acid involved in muscle protein synthesis, used as a workout supplement for athletic support.

Recommended Dose (Adults 19 years and older): Take one (1) scoop, up to three (3) times per day, or as directed by a healthcare practitioner. Mix product well in a cup of liquid (water, juice, etc.) and consume immediately. Recommended Duration of Use: Consult a healthcare practitioner for use beyond 2 weeks. Known Adverse Reactions: At 3 scoops per day, some people may experience gastrointestinal discomfort (such as diarrhea).

Cautions and Warnings: As with any natural health product, consult a healthcare practitioner prior to use of this product, especially if you are pregnant or breastfeeding. Ensure to drink enough fluid before, during and after exercise. Do not take within two hours of another medicine, as the effectiveness of the other medicine may be altered. Do not use if the safety seal is broken. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

Français

Chaque mesure contient :

  • L-glycine5 g

Ingrédients non médicinaux : Aucun ingrédient non médicinal.

Usage ou fins recommandés : La glycine (L-glycine) est un acide aminé qui participe à la synthèse des protéines musculaires et est utilisé comme supplément d'entraînement pour un soutien athlétique.

Dose recommandée (adultes de 19 ans et plus) : Prendre une (1) mesure, jusqu'à trois (3) fois par jour, ou selon l'avis d'un praticien de soins de santé. Bien mélanger le produit dans une tasse de liquide (eau, jus, etc.) et consommer immédiatement. Durée d'utilisation recommandée : Consulter un praticien de soins de santé pour un usage de plus de 2 semaines. Réactions indésirables connues : Lorsque 3 mesures par jour, certaines personnes pourraient manifester de l'inconfort gastro-intestinal (tel que la diarrhée).

Mises en garde et avertissements : Comme avec tout produit de santé naturel, consultez un praticien de soins de santé avant l'utilisation de ce produit, surtout si vous êtes enceinte ou allaitante. Assurez-vous de boire suffisamment de liquide avant, pendant et après l'exercice. Ne pas prendre dans les deux heures suivant la prise d'un autre médicament, car l'efficacité de ce médicament pourrait être altérée. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants.

NPN 80091468

5 g Pure L-Glycine per Scoop450 g · 90 servingsVegan · Non-GMO · Gluten-FreeMade in Canada

Add CanPrev L-Glycine to your daily routine

Get CanPrev L-Glycine Vegan Amino Acid Powder on Amazon.ca - fast, protected delivery.

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Why CanPrev L-Glycine

5 g of pure, fermentation-based L-Glycine per scoop - a clean, single-ingredient amino acid powder for athletic support and daily calm.

5 g pure L-Glycine per scoop

Each scoop delivers a full 5 g dose of fermentation-based L-Glycine, involved in muscle protein synthesis.

Clean, single-ingredient label

No fillers, binders, artificial colours, flavours or sweeteners - just L-Glycine, unflavoured and easy to mix.

Flexible daily dosing

Take 1 scoop, up to 3 times per day, mixed into water, juice or a smoothie - or as directed by a healthcare practitioner.

Trusted Canadian brand

CanPrev - formulated and made in Canada, licensed under NPN 80091468.

Inside every scoop

5 g of pure L-Glycine per scoop - take 1 scoop, up to 3 times daily, or as directed by a healthcare practitioner.

L-Glycine 5 g per scoop

How to use it

1 scoop, up to 3 times per day

Adults take one (1) scoop, up to three (3) times per day, or as directed by a healthcare practitioner.

Mix well and drink immediately

Mix the product well into a cup of liquid (water, juice, etc.) and consume immediately.

Know the guardrails

Consult a healthcare practitioner for use beyond 2 weeks. Do not take within two hours of another medicine, as its effectiveness may be altered. At 3 scoops per day, some people may experience gastrointestinal discomfort.

What the research says about Glycine

Educational summaries of published research on glycine generally; not product-specific claims. CanPrev L-Glycine's own label claim is the use authorized under NPN 80091468: an amino acid involved in muscle protein synthesis, used as a workout supplement for athletic support.

Sleep & Relaxation

A 2026 review named glycine among evidence-based sleep-promoting nutraceuticals

A narrative review of dietary and supplement protocols for sleep singled out glycine alongside melatonin, magnesium and L-theanine as compounds with evidence for supporting circadian rhythm and sleep quality.

Review
Conti, Nutrition Reviews (2026)
Sleep & Relaxation

3 g of glycine before bed reduced daytime fatigue after sleep restriction

In healthy volunteers whose sleep was cut by 25% for three nights, taking 3 g of glycine before bedtime significantly reduced next-day fatigue and improved psychomotor vigilance test performance versus placebo.

Human RCT
Bannai et al., Frontiers in Neurology (2012)
Sleep & Relaxation

Glycine's sleep-promoting, body-cooling effect traced to NMDA receptors in the brain's clock center

In rats, oral glycine induced sleep and lowered core body temperature by increasing skin blood flow through NMDA receptor activation in the suprachiasmatic nucleus (SCN) - an effect abolished when the SCN was removed.

Mechanism
Kawai et al., Neuropsychopharmacology (2014)
Muscle, Recovery & Exercise Performance

A 2024 review outlines glycine's potential as an ergogenic aid - with a clear high-dose caution

Reviewing cell, animal and early human evidence, researchers describe glycine's roles in muscle metabolism and possible benefits for power output, lactic acid clearance and sleep-linked recovery - while flagging that very high doses (over 500 mg/kg body mass) could cause cytotoxic and glutamate-related effects.

Review
Ramos-Jimenez et al., Sports (Basel) (2024)
Muscle, Recovery & Exercise Performance

Glycine-rich collagen peptides before bed reduced awakenings and sharpened next-day cognition in active men

Physically active men with sleep complaints who took 15 g of glycine-rich collagen peptides before bed had fewer polysomnography-recorded night awakenings and performed better on a Stroop cognitive test the next morning versus placebo, though sleep quantity and other measures were unchanged.

Human RCT
Thomas et al., European Journal of Nutrition (2023)
Muscle, Recovery & Exercise Performance

An honest null: raising plasma glycine via collagen or free amino acids did not boost post-exercise muscle protein synthesis

Ingesting a bolus of hydrolyzed collagen or free amino acids matching collagen's profile substantially raised circulating glycine but did not further increase myofibrillar or muscle connective-tissue protein synthesis rates at rest or after resistance exercise versus placebo.

Human RCT
Aussieker et al., Medicine & Science in Sports & Exercise (2025)
Collagen & Connective Tissue

Restoring glycine transport into skin cells revived collagen production in aged skin

In aged mouse skin and senescent human skin cells, boosting the glycine transporter GlyT1 increased intracellular glycine, raised glutathione, lowered oxidative stress and increased type I/III collagen synthesis and skin elasticity - effects blocked when GlyT1 was inhibited.

Animal & cell study
Byun et al., International Journal of Molecular Sciences (2025)
Collagen & Connective Tissue

A whey-plus-collagen blend that raised plasma glycine increased both muscle and connective-tissue protein synthesis

A 25 g whey plus 5 g collagen protein blend significantly raised plasma glycine and leucine and increased myofibrillar protein synthesis at rest and after exercise, plus muscle connective-tissue protein synthesis at rest, compared with a non-caloric placebo.

Human RCT
Aussieker et al., Medicine & Science in Sports & Exercise (2024)
Collagen & Connective Tissue

A second honest null: collagen peptides raised plasma glycine but didn't add to connective-tissue synthesis during a week of training

Twice-daily 15 g collagen peptide supplementation over one week of intense resistance training raised post-absorptive plasma glycine, proline and hydroxyproline versus placebo, but did not further increase myofibrillar or muscle connective protein synthesis rates.

Human RCT
Kirmse et al., Medicine & Science in Sports & Exercise (2024)
GlyNAC & Glutathione (Antioxidant Precursor)

A 2026 review: glycine plus N-acetylcysteine (GlyNAC) may counter aging hallmarks, especially alongside exercise

Glycine and NAC are both precursors of the antioxidant glutathione; this review summarizes evidence that combined GlyNAC supplementation improves oxidative stress, mitochondrial function, insulin resistance, inflammation, muscle strength and cognition in older adults, with the most compelling results when paired with exercise.

Review
Wang et al., Frontiers in Nutrition (2026)
GlyNAC & Glutathione (Antioxidant Precursor)

GlyNAC supplementation reversed brain glutathione deficiency and cognitive decline in old mice

Old mice fed a GlyNAC-supplemented diet for 8 weeks corrected age-related deficits in brain glutathione, oxidative stress, mitochondrial energetics and neurotrophic factors, and reversed the cognitive impairment seen in old control mice versus young mice.

Animal study
Kumar et al., Antioxidants (2023)
GlyNAC & Glutathione (Antioxidant Precursor)

GlyNAC raised antioxidant capacity and supported recovery in a rat spinal-cord-injury model

Rats given GlyNAC after spinal cord injury showed significantly higher glutathione and superoxide dismutase and lower oxidative-damage markers in spinal tissue, alongside improved motor-function recovery scores and reduced skeletal-muscle atrophy, versus untreated injured rats.

Animal study
Xu et al., Inflammation (2023)
Cardiovascular Health

Lower plasma glycine tracked with salt-sensitive high blood pressure in a human and rat study

In patients with salt-sensitive hypertension, plasma glycine was reduced by 61% versus controls and was the strongest single predictor of the condition; in salt-sensitive rats, glycine supplementation meaningfully reduced salt-induced high blood pressure by improving renal amino-acid metabolism and nitric oxide production.

Human & animal study
Yang et al., Hypertension Research (2025)
Cardiovascular Health

A 1,200-person study found higher plasma glycine linked to lower odds of stage-2 hypertension

In a nationwide Iranian metabolomics study of 1,200 adults, higher plasma glycine was independently associated with reduced odds of stage-2 hypertension after adjusting for age, sex, BMI and other cardiometabolic factors.

Human study
Arjmand et al., PLoS ONE (2023)
Cardiovascular Health

A GlyNAC diet improved heart function in aged male mice - but not females, an honest sex-specific result

Old mice fed a glycine-and-NAC-supplemented diet for 12 weeks showed improved mitochondrial enzyme activity and modestly better diastolic heart function - benefits seen in old male mice but not old females, whose exercise performance instead declined on the same diet.

Animal study
Angelini et al., Journals of Gerontology: Series A (2025)
Metabolic Health & Insulin Sensitivity

A review links low plasma glycine to insulin resistance and rising type 2 diabetes risk

Plasma glycine is characteristically low in people with obesity or diabetes, and prospective studies show low baseline glycine predicts future type 2 diabetes risk; this review maps the metabolic pathways - collagen, creatine, glutathione and heme synthesis among them - that depend on glycine.

Review
Adeva-Andany et al., Amino Acids (2017)
Metabolic Health & Insulin Sensitivity

Glycine supplementation eased diabetic kidney disease in mice via the AMPK/mTOR pathway

In diabetic mice, glycine supplementation reduced kidney damage, improved insulin sensitivity, lowered food intake and blood glucose, and reduced proximal-tubule cell injury by activating the AMPK/mTOR signaling pathway.

Animal study
Shao et al., Diabetologia (2024)
Metabolic Health & Insulin Sensitivity

Adolescents with insulin resistance had lower plasma glycine than insulin-sensitive peers

In a metabolomics study of obese adolescents, those with hyperinsulinemia/insulin resistance had significantly lower plasma glycine (alongside serine and myo-inositol) than adolescents with normal insulin levels, consistent with glycine's emerging role as a metabolic-health marker.

Human study
Mullner et al., Metabolomics (2021)
Cognitive Function & Neurotransmission

Oral glycine improved memory retrieval in both young and middle-aged adults

In a double-blind, randomized crossover trial, a bioavailable form of glycine significantly improved episodic memory retrieval in healthy students and middle-aged men, and specifically benefited sustained attention in the middle-aged group - without stimulant effects or mood changes.

Human RCT
File, Fluck & Fernandes, Journal of Clinical Psychopharmacology (1999)
Cognitive Function & Neurotransmission

A historical review traces glycine's establishment as one of the brain's core inhibitory neurotransmitters

This review recounts how glycine, alongside GABA, came to be recognized as a vital inhibitory neurotransmitter in the spinal cord and brain, acting through dedicated glycine receptors involved in motor reflex and pain-signaling pathways.

Review
Bowery & Smart, British Journal of Pharmacology (2006)
Cognitive Function & Neurotransmission

Newly identified 'excitatory' glycine receptors are reshaping understanding of glycine's brain signaling

Beyond its classic inhibitory role, glycine also activates a distinct excitatory receptor (eGlyR) in specific brain regions governing emotional responses - a discovery that broadens the known ways glycine tunes neuronal activity and behavior.

Review
Bossi et al., Trends in Neurosciences (2023)
Foundational Amino Acid Biology

A review catalogues glycine's wide-ranging roles across metabolism and disease prevention

This review summarizes how glycine, synthesized from serine, choline, hydroxyproline and threonine, serves as a precursor for creatine, glutathione, heme and purines, and surveys research on dietary glycine's role in supporting cardiovascular, inflammatory, metabolic and sleep-related health.

Review
Razak et al., Oxidative Medicine and Cellular Longevity (2017)
Foundational Amino Acid Biology

A 2026 review maps the enzyme pathway that interconverts glycine and serine in the body

Serine hydroxymethyltransferase (SHMT) governs the folate-dependent, one-carbon metabolic pathway connecting glycine and serine - the same biochemical route the body uses to make nucleotides and sustain redox balance - and this review surveys its regulation across tissues.

Review
Li et al., Journal of Translational Medicine (2026)
Foundational Amino Acid Biology

Lower plasma glycine tracked with early metabolic risk in children with obesity

In a study of 97 children and adolescents, those with obesity had significantly lower plasma glycine (and a lower glycine-to-branched-chain-amino-acid ratio) than healthy-weight peers, a pattern associated with early insulin resistance and metabolic dysregulation.

Human study
Oge Enver et al., Frontiers in Pediatrics (2025)

Customer Reviews

4.6 out of 5 · 273 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

How do I take CanPrev L-Glycine?

Adults take one (1) scoop, up to three (3) times per day, or as directed by a healthcare practitioner. Mix the product well into a cup of liquid (water, juice, etc.) and consume immediately.

What's in each scoop?

Each scoop contains 5 g of L-Glycine, fermentation-based. There are no non-medicinal ingredients - just pure L-Glycine.

What is the licensed use of this product?

This product's Health Canada licence (NPN 80091468) authorizes it as an amino acid involved in muscle protein synthesis, used as a workout supplement for athletic support.

Can I take this if I'm pregnant or breastfeeding?

Consult a healthcare practitioner before use if you are pregnant or breastfeeding.

Are there any interactions or cautions?

Do not take within two hours of another medicine, as its effectiveness may be altered. Ensure to drink enough fluid before, during and after exercise. Consult a healthcare practitioner for use beyond 2 weeks.

Does it have any side effects?

At 3 scoops per day, some people may experience gastrointestinal discomfort, such as diarrhea.

Is it vegan and allergen-friendly?

Yes - it is vegan, fermentation-based, and free of gluten, dairy, soy, wheat, yeast, sugar and artificial colours, flavours or preservatives.

Is CanPrev L-Glycine made in Canada?

Yes. It is formulated and made in Canada by CanPrev Natural Health Products Ltd. (Toronto, ON) and licensed by Health Canada under NPN 80091468.

5 g Pure L-Glycine per Scoop450 g · 90 servingsVegan · Non-GMO · Gluten-FreeMade in Canada

Add CanPrev L-Glycine to your daily routine

Get CanPrev L-Glycine Vegan Amino Acid Powder on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80091468. Glycine (L-Glycine) is an amino acid involved in muscle protein synthesis and used as a workout supplement for athletic support. Research summaries on this page concern glycine generally and are educational - they are not additional product-specific claims beyond this product's Health Canada-authorized use. Read and follow the label. Consult a health care practitioner before use, especially if pregnant or breastfeeding. Ensure to drink enough fluid before, during and after exercise. Do not take within two hours of another medicine, as its effectiveness may be altered. Results may vary.

Important information

Safety Information

Cautions and Warnings: As with any natural health product, consult a healthcare practitioner prior to use of this product, especially if you are pregnant or breastfeeding. Ensure to drink enough fluid before, during and after exercise. Do not take within two hours of another medicine, as the effectiveness of the other medicine may be altered. Do not use if the safety seal is broken. Keep out of reach of children.

Indications

Recommended Use or Purpose: Glycine (L-Glycine) is an amino acid involved in muscle protein synthesis, used as a workout supplement for athletic support.

Ingredients

Medicinal Ingredients (per 1 scoop): L-Glycine, 5 g. Non-medicinal Ingredients: None.

Directions

Recommended Dose (Adults 19 years and older): Take one (1) scoop, up to three (3) times per day, or as directed by a healthcare practitioner. Mix product well in a cup of liquid (water, juice, etc.) and consume immediately. Recommended Duration of Use: Consult a healthcare practitioner for use beyond 2 weeks. Known Adverse Reactions: At 3 scoops per day, some people may experience gastrointestinal discomfort (such as diarrhea).

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. This item is sold and shipped by Amazon.ca.

$35.99 CAD4.6 ★ (273) Get it on Amazon →