CanPrev Joint-Pro NEM - Eggshell Membrane & Glucosamine | 60 Caps
Visit the CanPrev Store| Brand | CanPrev |
| Serving | 1 capsule, 2 times per day |
| Licensed Natural Health Product | NPN 80031555 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- 250MG NEM, A PATENTED EGGSHELL MEMBRANE INGREDIENT: Natural Eggshell Membrane (partially hydrolysed chicken eggshell membrane) naturally contains collagen, glycosaminoglycans and hyaluronic acid - key components of healthy cartilage and joint tissue.
- HELPS MAINTAIN JOINT AND CARTILAGE HEALTH: The authorized use of this licensed Natural Health Product (NPN 80031555): helps to maintain joint and cartilage health and helps to reduce joint pain and stiffness associated with osteoarthritis of the knee.
- 750MG GLUCOSAMINE HYDROCHLORIDE PER CAPSULE: A well-studied amino sugar and natural constituent of cartilage glycosaminoglycans, dosed alongside NEM in every vegetable capsule.
- SIMPLE TWICE-DAILY VEGETABLE CAPSULES: Take just 1 capsule, 2 times per day, with or without food - no large tablets or complicated dosing schedule.
- MADE IN CANADA, NO FILLERS: Each bottle provides 60 vegetable capsules, a 30-day supply at the recommended dose - Non-GMO, gluten-free, dairy-free and soy-free, with no binders or fillers, formulated and made in Canada by CanPrev.
Product Description
Joint-Pro NEM - 250mg Natural Eggshell Membrane Plus 750mg Glucosamine Hydrochloride for Fast-Acting Joint & Cartilage Support
250mg of NEM (Natural Eggshell Membrane) - a patented ingredient naturally rich in collagen, glycosaminoglycans and hyaluronic acid - is paired with 750mg of Glucosamine Hydrochloride in every capsule. Helps to maintain joint and cartilage health and helps to reduce joint pain and stiffness associated with osteoarthritis of the knee. 60 vegetable capsules, a 30-day supply at 1 capsule taken twice daily. Licensed Natural Health Product. NPN 80031555. Licensed Natural Health Product NPN 80031555.
250 mg de NEM (membrane de coquille d'oeuf naturelle) - un ingrédient breveté naturellement riche en collagène, en glycosaminoglycanes et en acide hyaluronique - est combiné à 750 mg de chlorhydrate de glucosamine dans chaque capsule. Aide à maintenir la santé des articulations et du cartilage et aide à réduire la douleur et la raideur articulaires associées à l'arthrose du genou. 60 capsules végétales, un approvisionnement de 30 jours à raison d'une capsule prise deux fois par jour. Produit de santé naturel homologué. NPN 80031555.
A Fast-Acting Duo: NEM Plus Glucosamine Hydrochloride
250mg of patented NEM eggshell membrane and 750mg of Glucosamine Hydrochloride in every capsule - No Binders, No Fillers, Made in Canada
250mg NEM, a Patented Eggshell Membrane Ingredient
Natural Eggshell Membrane naturally contains collagen, glycosaminoglycans and hyaluronic acid - key building blocks for healthy cartilage and connective tissue.
750mg Glucosamine Hydrochloride Per Capsule
Glucosamine is a natural constituent of cartilage glycosaminoglycans and one of the most widely studied ingredients for joint comfort, paired here with NEM in a single easy-to-take vegetable capsule.
Advanced Ingredients, Superior Results
250mg of NEM (Natural Eggshell Membrane) - a patented ingredient naturally rich in collagen, glycosaminoglycans and hyaluronic acid - is paired with 750mg of Glucosamine Hydrochloride in every capsule. Helps to maintain joint and cartilage health and helps to reduce joint pain and stiffness associated with osteoarthritis of the knee. 60 vegetable capsules, a 30-day supply at 1 capsule taken twice daily. Licensed Natural Health Product. NPN 80031555.
Natural Eggshell Membrane (NEM)
A patented, partially hydrolysed chicken eggshell membrane ingredient naturally containing collagen, glycosaminoglycans and hyaluronic acid, studied for knee osteoarthritis pain and stiffness relief.
250 mg per capsule
Glucosamine Hydrochloride
An amino sugar and natural constituent of cartilage glycosaminoglycans, one of the most widely studied ingredients for joint comfort and cartilage support.
750 mg per capsuleCanPrev Joint-Pro NEM: Supplement Facts
Supplement Facts
- Natural Eggshell Membrane (NEM, partially hydrolysed chicken eggshell membrane)250 mg
- Glucosamine Hydrochloride750 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Vegetable-grade magnesium stearate, vegetable capsule. No binders. No fillers.
Recommended Use or Purpose: Helps to maintain joint and cartilage health. Helps to reduce joint pain and stiffness associated with osteoarthritis of the knee.
Recommended Dose (Adults 19 years and older): Take one (1) capsule, two (2) times per day, with or without food, or as directed by a health care practitioner. Duration of Use: Use for a minimum of 4 weeks to see beneficial effects. Consult a health care practitioner for use beyond 8 weeks.
Cautions and Warnings: As with any natural health product, consult a health care practitioner on the use of this product, especially if you are taking any medication or if you have a medical condition including an allergy to shellfish, or if symptoms worsen. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Do not use if the safety seal is broken. Keep out of reach of children. Known Adverse Reactions and Contraindications: Do not use if you have a known allergy to eggs or egg by-products. Known allergens of this product are eggs and crustaceans.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Fiche produit
- Membrane de coquille d'oeuf naturelle (membrane de coquille d'oeuf partiellement hydrolysée)250 mg
- Chlorhydrate de glucosamine750 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Stéarate de magnésium de grade végétal, capsule végétale. Sans agents liants ni agents de remplissage.
Usage ou fins recommandés : Aide à maintenir la santé des articulations et du cartilage. Aide à réduire la douleur et la raideur articulaires associées à l'arthrose du genou.
Posologie recommandée (Adultes de 19 ans et plus) : Prendre une (1) capsule, deux (2) fois par jour, avec ou sans nourriture, ou selon l'avis d'un praticien de soins de santé. Durée d'utilisation : Utiliser pendant au moins 4 semaines pour constater des effets bénéfiques. Consulter un praticien de soins de santé pour un usage de plus de 8 semaines.
Mises en garde et précautions : Comme pour tout produit de santé naturel, consultez un praticien de soins de santé concernant l'utilisation de ce produit, surtout si vous prenez tout médicament ou si vous souffrez d'un état médical incluant une allergie aux crustacés, ou si les symptômes s'aggravent. Consultez un praticien de soins de santé avant l'usage si vous êtes enceinte ou si vous allaitez. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants. Réactions indésirables et contre-indications connues : Ne pas utiliser si vous avez une allergie connue aux œufs ou aux sous-produits des œufs. Les allergènes connus de ce produit sont les œufs et les crustacés.
NPN 80031555
Support joint and cartilage health
Get CanPrev Joint-Pro NEM on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Joint-Pro NEM
250mg of patented NEM eggshell membrane and 750mg of Glucosamine Hydrochloride in every capsule - a fast-acting, clinically studied duo for joint and cartilage health.
Fast-Acting Joint Support
NEM and Glucosamine Hydrochloride together in a formula studied for pain and stiffness relief that can begin within days.
Helps maintain joint and cartilage health
The Health Canada-authorized use of this licensed Natural Health Product: helps to maintain joint and cartilage health and helps to reduce joint pain and stiffness associated with osteoarthritis of the knee.
Easy twice-daily capsule dosing
Just one vegetable capsule taken twice a day, with or without food - no large tablets or multi-pill routines to manage.
Licensed, made in Canada
NPN 80031555. Non-GMO, gluten-free, dairy-free and soy-free, with no binders or fillers - formulated and made in Canada by CanPrev.
Inside every capsule
250mg Natural Eggshell Membrane (NEM) and 750mg Glucosamine Hydrochloride - a fast-acting joint-support duo in vegetable capsules, no binders or fillers.
How to use it
Take 1 capsule, twice daily
Adults (19 years and older): take one (1) capsule, two (2) times per day, or as directed by a health care practitioner.
With or without food
Joint-Pro NEM can be taken with or without food, whichever is most convenient for your routine.
Allow at least 4 weeks to see results
Use for a minimum of 4 weeks to see beneficial effects. Consult a health care practitioner for use beyond 8 weeks.
Keep the safety seal intact
Do not use if the safety seal is broken, and keep the bottle out of reach of children.
What the research says about this formula's key ingredients
Educational summaries of published research on Natural Eggshell Membrane (NEM) and Glucosamine Hydrochloride generally; not product-specific claims. CanPrev Joint-Pro NEM's own claim is the authorized use under NPN 80031555: helps to maintain joint and cartilage health and helps to reduce joint pain and stiffness associated with osteoarthritis of the knee.
8-week RCT: NEM significantly reduced knee osteoarthritis pain and stiffness after just 10 days
In a randomized, multicenter, double-blind, placebo-controlled trial of 67 patients with knee osteoarthritis, 500mg/day of Natural Eggshell Membrane (NEM) produced a statistically significant reduction in mean pain (15.9%, P=0.036) and stiffness (12.8%, P=0.024) subscores versus placebo after only 10 days, sustained through 60 days.
Human RCT12-week RCT: eggshell membrane relieved self-reported knee pain and daily-life function from week 1
In a randomized, double-blind, placebo-controlled trial of 150 adults with knee osteoarthritis, a daily 300mg eggshell membrane capsule produced significantly greater improvement than placebo on the KOOS 'Pain' and 'Daily Life' functioning subscales, with effects emerging as early as 1 week after starting treatment.
Human RCTMeta-analysis of 7 RCTs: eggshell membrane significantly improved WOMAC pain and total scores in knee osteoarthritis
A systematic review and meta-analysis of 7 randomized controlled trials found eggshell membrane (ESM) supplementation produced significant improvement in total WOMAC osteoarthritis index score and the WOMAC pain subscale compared to placebo in people with knee osteoarthritis.
Systematic review & meta-analysis2-week RCT: NEM reduced a cartilage-breakdown biomarker during exercise in healthy adults
In a randomized, placebo-controlled trial of 60 healthy postmenopausal women performing a moderate exercise regimen, 500mg/day of NEM significantly reduced the cartilage degradation biomarker CTX-II versus placebo after 1 week (-17.2%, P=0.002) and 2 weeks (-9.9%, P=0.042), alongside faster recovery from exercise-induced stiffness and pain.
Human RCTNEM was well tolerated with no serious adverse events over 8 weeks of use
The same 67-patient randomized, placebo-controlled knee osteoarthritis trial that established NEM's pain- and stiffness-relieving effect also reported no serious adverse events, with the 500mg daily dose described by researchers as well tolerated by study participants throughout the 8-week trial.
Human RCT (safety data)Meta-analysis: eggshell membrane is a safe, natural adjunct for knee osteoarthritis care
The same systematic review and meta-analysis of 7 randomized controlled trials concluded that eggshell membrane supplementation is a promising adjunctive treatment for knee osteoarthritis, offering a safe, natural option to help enhance quality of life alongside standard care.
Systematic review & meta-analysis12-week RCT: a glucosamine hydrochloride and chondroitin sulfate combination significantly improved WOMAC pain and total scores
In a randomized, double-blind, placebo-controlled trial of 101 adults with knee osteoarthritis, a combination of glucosamine hydrochloride and chondroitin sulfate produced significantly greater improvement in WOMAC total score and knee pain than placebo, with the effect statistically significant as early as 4 weeks.
Human RCT12-week RCT: a collagen, glucosamine hydrochloride and chondroitin formulation improved knee osteoarthritis symptoms and sport/recreation scores
In a 12-week randomized, double-blind, placebo-controlled pilot study of 54 adults with mild-to-moderate knee pain, a formulation containing collagen type II, glucosamine hydrochloride and chondroitin sulfate produced significant improvements versus placebo in KOOS symptom (+8.16%), sport/recreation (+25.25%) and quality-of-life (+27.66%) subscales.
Human RCT (pilot)Multicenter RCT: a glucosamine hydrochloride plus chondroitin sulfate capsule produced meaningful analgesic relief in knee osteoarthritis
In a 100-patient, multicenter, randomized, double-blind trial, a fixed-dose combination capsule of glucosamine hydrochloride and chondroitin sulfate (Cosamin DS) produced investigator-assessed analgesic efficacy in 85.4% of patients with knee osteoarthritis, with pain intensity significantly reduced from baseline and good tolerability.
Human RCT (multicenter)12-week RCT: a glucosamine hydrochloride-containing formulation improved stiffness and physical quality-of-life scores
In the same 12-week randomized, placebo-controlled pilot study, the collagen/glucosamine hydrochloride/chondroitin formulation improved KOOS stiffness scores by 14.68% versus baseline and produced significant gains in SF-36 physical component scores, with a linear improvement trend over the full 12 weeks.
Human RCT (pilot)RCT: glucosamine hydrochloride plus exercise therapy improved knee range of motion and functional performance
In a randomized trial of 60 patients with knee osteoarthritis, glucosamine hydrochloride combined with exercise therapy improved knee flexion range of motion, Lysholm functional scores, five-time sit-to-stand performance and walking speed versus baseline, with greater gains when combined with an additional muscle-relaxant therapy.
Human RCT6-month RCT: a glucosamine hydrochloride and chondroitin combination improved WOMAC index and quality of life
In a randomized trial of 70 patients with knee osteoarthritis followed for 6 months, a glucosamine hydrochloride plus chondroitin sulfate combination produced sustained improvement in the WOMAC index and reduced pain, with gains in the physical component of SF-36 quality-of-life scores at 1, 3 and 6 months.
Human RCTRCT: glucosamine hydrochloride combined with exercise therapy reduced inflammatory markers linked to cartilage breakdown
In the same 60-patient randomized trial, glucosamine hydrochloride plus exercise therapy reduced serum levels of the inflammatory and cartilage-breakdown markers MMP-3, TNF-alpha and IL-6, with significantly greater reductions when combined with an additional muscle-relaxant therapy.
Human RCTRCT: adding glucosamine hydrochloride to standard therapy lowered inflammatory factors and pain scores in knee osteoarthritis
In a randomized trial of 128 patients with early- to mid-stage knee osteoarthritis, adding glucosamine hydrochloride to celecoxib therapy produced significantly lower inflammatory factor levels (TNF-alpha, IL-6, IL-1beta, hs-CRP) and lower Lequesne and VAS pain scores than celecoxib alone, with fewer adverse reactions overall.
Human RCTRCT: glucosamine hydrochloride as routine comparator therapy improved knee osteoarthritis pain and function scores
In a 292-patient randomized trial, routine treatment with glucosamine hydrochloride tablets plus intra-articular sodium hyaluronate significantly reduced VAS pain scores and improved Hospital for Special Surgery (HSS) knee scores compared to baseline, alongside improvements in joint-fluid inflammatory markers.
Human RCT6-month RCT: a glucosamine hydrochloride combination reduced MRI-measured joint synovitis
In the same 6-month randomized trial, the glucosamine hydrochloride plus chondroitin sulfate comparator group showed improved cartilage ultrastructure on T2-mapping MRI and a reduction in synovitis area (1.37-fold) after 6 months of use, alongside its WOMAC and pain improvements.
Human RCT6-week RCT: a glucosamine hydrochloride and chondroitin sulfate combination improved pain, stiffness and physical function
In a randomized, open-label, active-controlled trial, a standard twice-daily combination of 500mg glucosamine hydrochloride and 415mg chondroitin sulfate produced significant improvement from baseline in VAS pain and in the WOMAC pain, stiffness and physical function subscales over 6 weeks, alongside a reduction in inflammatory marker levels.
Human RCTSystematic review of 15 RCTs: glucosamine significantly reduced global knee osteoarthritis pain versus placebo
A systematic review of 15 randomized controlled trials found glucosamine supplementation significantly reduced global pain, as measured by the Visual Analog Scale, compared with placebo in knee osteoarthritis patients, with WOMAC data confirming improvement in pain, stiffness and physical function.
Systematic reviewSystematic review of 15 RCTs: no serious adverse events or drug interactions reported with glucosamine
The same systematic review of 15 randomized controlled trials found no reports of serious medication interactions or significant adverse events with glucosamine supplementation across the studies reviewed, supporting long-term tolerability at standard doses.
Systematic reviewPost-marketing safety review: glucosamine's most common reported reactions are mild allergic and gastrointestinal effects
A systematic review of post-marketing safety surveillance studies for anti-osteoarthritis medications found that the most commonly reported adverse events associated with non-pharmaceutical-grade glucosamine and chondroitin products were allergic reactions and gastrointestinal disorders, with no new significant safety signal identified beyond these known effects.
Systematic review (post-marketing surveillance)Multicenter RCT: glucosamine hydrochloride and glucosamine sulfate combination capsules showed comparable, good tolerability
In the same 100-patient multicenter trial comparing two fixed-dose combination capsules, both the glucosamine sulfate/chondroitin sulfate formulation and the glucosamine hydrochloride/chondroitin sulfate formulation (Cosamin DS) showed similar rates of adverse events, with researchers concluding both presented good safety and tolerability profiles.
Human RCT (multicenter)Review: glucosamine's proposed mechanism includes inhibiting IL-1-induced NF-kB activation in cartilage cells
A pharmacology review describes glucosamine as a natural amino monosaccharide constituent of cartilage glycosaminoglycans, with proposed anti-catabolic actions including decreased interleukin-1-induced gene expression via inhibition of the NF-kB inflammatory signaling cascade in chondrocytes.
ReviewPreclinical study: chitosan-based formulations improved the oral absorption of glucosamine hydrochloride
A preclinical pharmacokinetic study in cell, rodent and dog models found that glucosamine hydrochloride has low and variable oral bioavailability due to transport-limited intestinal absorption, and that co-formulating it with chitosan meaningfully enhanced its intestinal permeability and measured bioavailability versus commercial reference products.
Preclinical pharmacokinetic studySystematic review of 15 RCTs: WOMAC-measured benefits of glucosamine were real but modest in size
The same systematic review of 15 randomized controlled trials found that while the WOMAC scale confirmed improvement in pain, stiffness and physical function with glucosamine supplementation, the size of these effects was modest - a calibration point worth pairing with NEM's faster-acting, larger effect sizes seen in the eggshell-membrane trials above.
Systematic reviewFrequently asked questions
What is CanPrev Joint-Pro NEM and what does it do?
It's a vegetable-capsule joint-support formula providing 250mg of Natural Eggshell Membrane (NEM) and 750mg of Glucosamine Hydrochloride per capsule. It helps to maintain joint and cartilage health and helps to reduce joint pain and stiffness associated with osteoarthritis of the knee.
How much do I take?
Adults 19 years and older take one (1) capsule, two (2) times per day, or as directed by a healthcare practitioner. Use for a minimum of 4 weeks to see beneficial effects; consult a health care practitioner for use beyond 8 weeks.
What ingredients are in the formula?
Each capsule contains Natural Eggshell Membrane (NEM, partially hydrolysed chicken eggshell membrane) 250mg and Glucosamine Hydrochloride 750mg. Non-medicinal ingredients: vegetable-grade magnesium stearate, vegetable capsule. No binders, no fillers.
How long does one bottle last?
Each bottle contains 60 vegetable capsules, a 30-day supply at the recommended dose of 1 capsule twice per day.
Are there any cautions?
Do not use if you have a known allergy to eggs or egg by-products. Consult a health care practitioner before use if you are pregnant or breastfeeding, taking any medication, or have a medical condition including an allergy to shellfish. Do not use if the safety seal is broken.
Is NEM the same as glucosamine and chondroitin alone?
No. NEM (Natural Eggshell Membrane) is a distinct, patented ingredient that naturally contains collagen, glycosaminoglycans and hyaluronic acid alongside the Glucosamine Hydrochloride in this formula - a different active than a glucosamine-and-chondroitin-only product.
Is it Non-GMO and free of common allergens like gluten and dairy?
Yes - the label states it is Non-GMO, gluten-free, dairy-free and soy-free, with no artificial colours, flavours or preservatives. Note that eggs are a known allergen for this product, and glucosamine hydrochloride is typically shellfish-derived.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support joint and cartilage health
Get CanPrev Joint-Pro NEM on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80031555. Helps to maintain joint and cartilage health. Helps to reduce joint pain and stiffness associated with osteoarthritis of the knee. The research summaries below concern Natural Eggshell Membrane (NEM) and Glucosamine Hydrochloride generally and are educational - they are not claims about this finished product. Consult a health care practitioner prior to use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, consult a health care practitioner on the use of this product, especially if you are taking any medication or if you have a medical condition including an allergy to shellfish, or if symptoms worsen. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Do not use if the safety seal is broken. Keep out of reach of children. Known Adverse Reactions and Contraindications: Do not use if you have a known allergy to eggs or egg by-products. Known allergens of this product are eggs and crustaceans.
Indications
Recommended Use or Purpose: Helps to maintain joint and cartilage health. Helps to reduce joint pain and stiffness associated with osteoarthritis of the knee.
Ingredients
Medicinal Ingredients (per capsule): Natural Eggshell Membrane (NEM, partially hydrolysed chicken eggshell membrane) 250 mg; Glucosamine Hydrochloride 750 mg. Non-medicinal ingredients: Vegetable-grade magnesium stearate, vegetable capsule. No binders. No fillers. Non-medicinal ingredients are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults 19 years and older): Take one (1) capsule, two (2) times per day, with or without food, or as directed by a health care practitioner. Duration of Use: Use for a minimum of 4 weeks to see beneficial effects. Consult a health care practitioner for use beyond 8 weeks.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.