CanPrev Heme Iron - Vitamin C, B12 & Folate | 60 V-Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 Vegetable Capsule |
| Licensed Natural Health Product | NPN 80124890 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- BOVINE-SOURCED HEME IRON: 11 mg of heme iron polypeptide per capsule - the same highly bioavailable iron form found naturally in meat, absorbed through a distinct pathway from plant-based (non-heme) iron sources.
- GENTLE ON DIGESTION: Formulated to be easy to digest, helping avoid the constipation and stomach upset commonly associated with standard iron salts such as ferrous sulfate.
- FOUR SUPPORTING COFACTORS: Vitamin C (PureWay-C) 50 mg, citrus bioflavonoids 1 mg, folate (L-5-methyltetrahydrofolate) 400 mcg and Vitamin B12 (methylcobalamin) 400 mcg alongside iron in one capsule.
- HELPS FORM RED BLOOD CELLS: Helps to form red blood cells and helps in energy metabolism.
- SUPPORTS NORMAL FETAL DEVELOPMENT: Helps to support normal early fetal development - formulated with expectant mothers' nutritional needs in mind.
- ONCE DAILY, EASY TO TAKE: Just 1 vegetable capsule daily with food - 60 capsules provide up to a 60-day supply.
- CLEAN CANADIAN FORMULA: Gluten-free, dairy-free and soy-free, in a vegetable capsule with a short non-medicinal ingredient list.
- PREMIUM CANPREV QUALITY: Made in Canada in a GMP-compliant facility, licensed under Health Canada NPN 80124890.
Product description
CanPrev Heme Iron - Gentle Bioavailable Iron with Vitamin C, Folate & B12
11 mg of bovine-sourced heme iron polypeptide alongside Vitamin C, citrus bioflavonoids, folate and Vitamin B12 in one small vegetable capsule - to help form red blood cells, support energy metabolism, and help support normal early fetal development. Licensed Natural Health Product NPN 80124890.
11 mg de polypeptide de fer héminique d'origine bovine, accompagné de vitamine C, de bioflavonoïdes d'agrumes, de folate et de vitamine B12 dans une seule petite capsule végétale - pour aider à la formation des globules rouges, soutenir le métabolisme énergétique et aider à soutenir le développement précoce normal du foetus.
CanPrev Heme Iron 60 V-Caps
A gentle, bioavailable heme iron complex - bovine-sourced heme iron plus four supporting cofactors in one daily vegetable capsule.
Bioavailable Heme Iron
11 mg of heme iron polypeptide, a bovine-sourced form absorbed through a distinct intestinal pathway from plant-based (non-heme) iron, formulated to be gentle on digestion compared with standard iron salts.
Red Blood Cells, Energy & Fetal Development
Iron, vitamin C, folate and vitamin B12 together help form red blood cells, help in energy metabolism, and help support normal early fetal development.
Advanced Ingredients, Superior Results
Five real actives - heme iron and its four supporting nutrients, here is what each contributes.
Iron (Heme Iron Polypeptide)
A bovine-sourced heme iron polypeptide - the same iron form found naturally in meat, absorbed through a distinct intestinal pathway from plant-based (non-heme) iron. Helps in the formation of red blood cells.
11 mg per capsuleVitamin C (PureWay-C - Ascorbic Acid)
An antioxidant vitamin form of ascorbic acid that supports immune function and works alongside this formula's iron and cofactor nutrients.
50 mg per capsuleCitrus Bioflavonoids
A blend of natural bioflavonoids from citrus fruit (lime, lemon, grapefruit, mandarin and orange), traditionally paired with vitamin C in supplement formulas.
1 mg per capsule
Folate (as L-5-Methyltetrahydrofolate)
The active, bioavailable form of folate - helps in the formation of red blood cells and supports normal early fetal development.
400 mcg per capsuleVitamin B12 (as Methylcobalamin)
The methylated, bioactive form of vitamin B12 - helps in the formation of red blood cells and supports energy metabolism.
400 mcg per capsuleCanPrev Heme Iron: Supplement Facts
Each capsule contains:
- Vitamin C (PureWay-C - ascorbic acid)50 mg
- Iron (heme iron polypeptide)11 mg
- Citrus Bioflavonoids (Citrus aurantiifolia, limon, paradisi, reticulata, sinensis)1 mg
- Folate (L-5-methyltetrahydrofolate)400 mcg
- Vitamin B12 (methylcobalamin)400 mcg
Non-Medicinal Ingredients: Hypromellose, magnesium stearate, microcrystalline cellulose, rice bran oil.
Recommended Use or Purpose: Helps to form red blood cells. Helps in energy metabolism. Helps to support normal early fetal development. Licensed Natural Health Product, NPN 80124890.
Recommended Dose (Adults 19 years and older, including pregnant and breastfeeding women): Take 1 capsule per day. Take with food, a few hours before or after taking other medications or natural health products.
Cautions and Warnings: Do not use this product if you have an allergy to bovine products. Consult a health-care practitioner prior to use if you have a peptic ulcer, regional enteritis, ulcerative colitis, hemochromatosis, other types of anemia, or repeated blood transfusions, or if you have stomach or intestinal problems. Consult a health-care practitioner prior to use if you are using methyldopa or other iron-containing products - iron supplements can decrease the absorption of drugs such as tetracycline, other antibiotics, penicillamine, cefdinir, chloramphenicol, levothyroxine, levodopa and quinolone antibiotics. Stop use if hypersensitivity/allergy occurs. Possible side effects: constipation, diarrhea, nausea, upset stomach and stomach/abdominal cramping may occur; iron may cause stools to turn black, an effect that is not harmful. This product may interfere with certain laboratory tests (including testing for blood in stool), possibly causing false results - make sure laboratory personnel and all doctors know you are taking this product. Take a few hours before or after taking other medications or natural health products. Keep out of reach of children. There is enough drug in this package to seriously harm a child.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Chaque capsule contient :
- Vitamine C (PureWay-C - acide ascorbique)50 mg
- Fer (polypeptide de fer héminique)11 mg
- Bioflavonoïdes d'agrumes (Citrus aurantiifolia, limon, paradisi, reticulata, sinensis)1 mg
- Folate (l-5-méthyltétrahydrofolate)400 mcg
- Vitamine B12 (méthylcobalamine)400 mcg
Ingrédients non médicinaux : Hypromellose, stéarate de magnésium, cellulose microcristalline, huile de son de riz.
Usage ou fins recommandés : Aide à la formation des globules rouges. Aide au métabolisme de l'énergie. Aide à soutenir le développement précoce normal du foetus. Produit de santé naturel homologué, NPN 80124890.
Dose recommandée (adultes de 19 ans et plus, y compris les femmes enceintes ou qui allaitent) : Prendre 1 capsule par jour. Prendre avec de la nourriture, à quelques heures d'intervalle de la prise d'autres médicaments ou produits de santé naturels.
Mises en garde et précautions : Ne pas utiliser ce produit si vous avez une allergie aux produits de source bovine. Consultez un praticien de soins de santé avant l'utilisation si vous souffrez d'un ulcère gastroduodénal, d'entérite régionale, de colite ulcéreuse, d'hémochromatose, d'autres types d'anémie, ou si vous avez reçu des transfusions sanguines à répétition, ou si vous avez des problèmes d'estomac ou d'intestins. Consultez un praticien de soins de santé avant d'utiliser du polypeptide de fer héminique si vous utilisez de la méthyldopa ou d'autres produits contenant du fer - les suppléments de fer peuvent réduire l'absorption de médicaments tels que la tétracycline, d'autres antibiotiques, la pénicillamine, le cefdinir, le chloramphénicol, la lévothyroxine, la lévodopa et les antibiotiques quinolones. Cessez l'utilisation en cas d'hypersensibilité ou d'allergie. Effets secondaires possibles : constipation, diarrhée, nausées, maux d'estomac et crampes d'estomac ou abdominales peuvent survenir; le fer peut causer un noircissement des selles, un effet sans danger. Ce produit peut interférer avec certains tests de laboratoire (y compris la recherche de sang dans les selles), pouvant fausser les résultats - informez le personnel de laboratoire et tous vos médecins que vous prenez ce produit. Prendre à quelques heures d'intervalle de la prise d'autres médicaments ou produits de santé naturels. Garder hors de la portée des enfants. Ce contenant contient assez de fer pouvant causer des torts sérieux à un enfant.
NPN 80124890
Support red blood cell formation the gentle way
Get CanPrev Heme Iron on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Heme Iron
A gentle, bioavailable heme iron complex - four ways it supports healthy blood and energy.
Bioavailable Heme Iron
11 mg of bovine-sourced heme iron polypeptide - the same iron form found in meat, absorbed via a distinct pathway from plant-based iron.
Gentle on Digestion
Formulated to help avoid the stomach upset and constipation commonly linked to standard iron salts.
Helps Form Red Blood Cells
Iron, vitamin C, folate and vitamin B12 each help form red blood cells and support energy metabolism.
Supports Early Fetal Development
Helps to support normal early fetal development, with folate and B12 alongside iron - suited to expectant mothers' needs.
Inside every capsule
11 mg of bovine-sourced heme iron polypeptide plus Vitamin C, citrus bioflavonoids, folate and Vitamin B12 - five real actives that help form red blood cells, support energy metabolism, and help support normal early fetal development.
How to use
Take 1 capsule daily
Adults 19 years and older (including pregnant and breastfeeding women): take 1 capsule per day.
Take with food
Take with food, a few hours before or after taking other medications or natural health products.
Check other iron sources
If you are also taking a prenatal multivitamin or another iron-containing product, consult a health-care practitioner first.
Store safely
Keep out of reach of children and store in a cool, dry place - 60 capsules provide up to a 60-day supply at 1 capsule daily.
What the research says about heme iron and its cofactor nutrients
Peer-reviewed studies and reviews on heme iron polypeptide, vitamin C, folate and vitamin B12 - shared for education, not as claims about this finished product. CanPrev Heme Iron's claims are the statements authorized under its Natural Health Product licence, NPN 80124890.
Bovine-derived heme iron peptide restored anemia markers in rats
A study of iron-deficient rats found a heme iron enriched peptide from bovine hemoglobin restored hemoglobin, red blood cell count, hematocrit and serum iron to normal or better levels, with higher iron bioavailability and fewer side effects than ferrous sulfate.
Animal studyHeme iron is absorbed intact through its own pathway
A review of intestinal iron absorption explains that heme iron, present in foods like meat, is absorbed intact through a distinct mechanism, while the bioavailability of non-heme iron varies widely depending on other components of the diet.
ReviewHeme-containing proteins are a promising bioavailable iron source
A review of dietary heme-containing proteins such as hemoglobin and myoglobin describes them as promising sources for iron supplementation and food fortification, citing their higher bioavailability and fewer side effects compared with conventional iron sources.
ReviewHeme iron polypeptide improved several iron-status markers in anemic infants
A randomized controlled trial in anemic Gambian infants found heme iron polypeptide (HIP) and ferrous sulfate produced similar improvements in hemoglobin and ferritin, but infants receiving HIP had higher serum iron and transferrin saturation and a greater improvement in inflammation-adjusted ferritin, with no difference in adverse events.
Human RCTHigher bioavailability reported in healthy subjects, mixed results in kidney disease
A review of heme iron polypeptide for anemia of chronic kidney disease notes it has been reported to have higher bioavailability and fewer side effects than non-heme iron in healthy subjects, but found no clear benefit over traditional iron supplementation in kidney disease patients specifically, at a higher cost.
ReviewAbsorption depends on the gut environment, not iron form alone
A randomized trial in women who had undergone gastric bypass surgery found standard ferrous sulfate corrected iron deficiency effectively while heme iron polypeptide did not, in this particular malabsorptive population - a reminder that the digestive environment, not just the iron form, affects how well iron is absorbed.
Human RCTHeme iron showed higher bioavailability than non-heme iron
A comparative digestion study found that iron from meat and extracted hemoglobin (heme iron) showed higher bioavailability than iron from wheat flour or extracted ferritin (non-heme iron), and that ascorbic and citric acid enhanced cellular uptake of the extracted proteins.
Comparative studyAlgorithms classify meals by their heme iron content
A review of methods for predicting dietary iron bioavailability describes algorithms that estimate a meal's overall iron bioavailability based on its content of heme iron alongside the enhancers and inhibitors that affect non-heme iron absorption.
ReviewHuman intestinal tissue expresses a distinct heme iron transporter
A study of small intestine tissue samples measured gene expression of both non-heme iron transporters (ferroportin, DMT1) and the heme iron transporter HCP1, confirming that heme iron uses its own dedicated uptake pathway distinct from non-heme iron transporters in humans.
Human tissue studyDaily iron supplementation reduces anemia but raises GI symptoms
A Cochrane review of daily iron supplementation in menstruating women found it effectively reduced anemia and fatigue, but was linked to an increased prevalence of gastrointestinal side effects including diarrhea and constipation compared with control.
Cochrane reviewLiposomal iron was better tolerated, standard iron raised hemoglobin more
A randomized trial in children with iron deficiency anemia found liposomal iron had better oral tolerance and fewer reports of constipation than ferrous ascorbate, though ferrous ascorbate produced a greater rise in hemoglobin over one month.
Human RCTA simple questionnaire captured early GI side effects of iron salts
A placebo-controlled trial developing a gastrointestinal symptom questionnaire found participants taking ferrous sulfate reported significantly more symptoms than those on placebo, with heartburn, abdominal pain and black stools the most distinguishing symptoms.
Human RCTIron supplementation eased fatigue even without anemia
A meta-analysis of randomized trials and pre-post studies found iron supplementation in non-anemic children, adolescents and menstruating adults improved fatigue, physical well-being and short-term memory, with effects concentrated in those who were iron deficient.
Meta-analysisCombining exercise with iron supplementation reduced fatigue further
A randomized trial in young women with iron deficiency anemia, all receiving iron supplementation, found those who also completed an 8-week structured training program had significantly greater reductions in general and physical fatigue than iron supplementation alone.
Human RCTSupporting adherence to iron therapy improved energy scores
A randomized trial in adults with iron deficiency anemia found a nurse-led education program to support treatment adherence was associated with significantly lower fatigue scores and higher energy scores after treatment compared with a control group.
Human RCTCorrecting folate deficiency prevents megaloblastic anemia
A laboratory review of folate status explains that folate becomes fixed in red blood cells during their production, and that detecting and correcting folate deficiency prevents megaloblastic anemia and reduces the risk of neural tube defects.
ReviewVitamin B12 or folate deficiency is the leading cause of megaloblastic anemia
A review of megaloblastic anemia diagnosis identifies vitamin B12 or folate deficiency as the most frequent underlying causes, with serum B12, serum folate and red cell folate assays as the primary diagnostic investigations.
ReviewLow B12 and folate were linked to abnormal red cell precursor markers
A comparative study of megaloblastic anemia patients found the large majority had low vitamin B12 and folate levels alongside elevated homocysteine, with a marker of abnormal cell turnover (p53) significantly elevated in their bone marrow compared with controls.
Comparative studyA vitamin C-rich fruit roughly doubled non-heme iron absorption
A human isotope study in adolescents found adding guava, rich in vitamin C, to a rice-based meal significantly increased non-heme iron absorption compared with the same meal without guava, in both girls and boys.
Human studyVitamin C fuels the enzyme that prepares non-heme iron for uptake
A review of iron metabolism describes how intestinal ascorbate (vitamin C) supplies electrons to the enzyme duodenal cytochrome b, which reduces non-heme dietary iron to the ferrous form required for uptake by intestinal iron transporters.
ReviewVitamin C enhances iron bioavailability by changing its chemical form
A review of anemia and micronutrients notes that vitamin C enhances iron bioavailability by reducing ferric iron to the more absorbable ferrous form, and that conditions which lower gastric vitamin C can in turn impair iron absorption.
ReviewIron caused over 30% of accidental poisoning deaths in children
An evidence-based consensus guideline notes that from 1983 to 1991, iron caused over 30% of deaths from accidental ingestion of drug products by children, and sets clear thresholds for when a child who has swallowed iron needs urgent medical care.
Consensus guidelineResearchers identified the toxic dose threshold for children
A study of 83 Turkish children with accidental and intentional iron poisoning determined that ingesting as little as 28 mg of elemental iron per kilogram of body weight was enough to trigger serious toxicity requiring treatment.
Retrospective studyChildren were poisoned by their mothers' own iron supplements
A case series of five children hospitalized after accidental iron poisoning found all had ingested iron tablets belonging to their pregnant mothers, and two developed fulminant hepatic failure and died despite treatment - underscoring why iron supplements must be kept out of children's reach.
Case seriesFrequently asked questions
What is CanPrev Heme Iron?
CanPrev Heme Iron provides 11 mg of bovine-sourced heme iron polypeptide plus Vitamin C, citrus bioflavonoids, folate and Vitamin B12 per capsule, in 60 vegetable capsules. It helps form red blood cells, helps in energy metabolism, and helps support normal early fetal development. It is a licensed Natural Health Product, NPN 80124890.
What makes heme iron different from other iron supplements?
Heme iron polypeptide is the same iron form found naturally in meat and is absorbed through a different intestinal pathway than plant-based (non-heme) iron sources like ferrous sulfate or iron bisglycinate, which may make it gentler on digestion for some people.
Will this cause constipation?
CanPrev Heme Iron is formulated to be gentle on digestion. As with any iron supplement, some people may still experience mild constipation, diarrhea, nausea or stomach upset - iron can also cause stools to turn black, which is not harmful.
What cofactors are included and why?
Each capsule also provides Vitamin C (PureWay-C, 50 mg), citrus bioflavonoids (1 mg), folate as L-5-methyltetrahydrofolate (400 mcg) and Vitamin B12 as methylcobalamin (400 mcg) - nutrients that work alongside iron to help form red blood cells and support energy metabolism.
How do I take it?
Adults 19 years and older (including pregnant and breastfeeding women) take 1 capsule daily with food, a few hours before or after other medications or natural health products.
Is it suitable during pregnancy?
CanPrev Heme Iron is formulated with folate and Vitamin B12 to help support normal early fetal development. As with any supplement, pregnant or breastfeeding women should consult a health-care practitioner before use, especially if already taking a prenatal multivitamin or another iron-containing product.
Are there any safety warnings I should know about?
Yes. Keep out of reach of children - there is enough iron in this package to seriously harm a child. Do not use if you have an allergy to bovine products. Consult a health-care practitioner before use if you have a peptic ulcer, regional enteritis, ulcerative colitis, hemochromatosis, other types of anemia, or repeated blood transfusions, or if you are using methyldopa or another iron-containing product.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support red blood cell formation the gentle way
Get CanPrev Heme Iron on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80124890. CanPrev Heme Iron helps to form red blood cells, helps in energy metabolism, and helps to support normal early fetal development. The research summaries below concern heme iron and its cofactor nutrients (Vitamin C, citrus bioflavonoids, folate and Vitamin B12) and are educational - they are not claims about this finished product. Read and follow the label. Keep out of reach of children. Consult a health-care practitioner prior to use if you are pregnant, breastfeeding, or taking another iron-containing supplement. Results may vary.
Important information
Safety Information
Cautions and Warnings: Do not use this product if you have an allergy to bovine products. Consult a health-care practitioner prior to use if you have a peptic ulcer, regional enteritis, ulcerative colitis, hemochromatosis, other types of anemia, or repeated blood transfusions, or if you have stomach or intestinal problems. Consult a health-care practitioner prior to use if you are using methyldopa or other iron-containing products - iron supplements can decrease the absorption of drugs such as tetracycline, other antibiotics, penicillamine, cefdinir, chloramphenicol, levothyroxine, levodopa and quinolone antibiotics. Stop use if hypersensitivity/allergy occurs. Possible side effects: constipation, diarrhea, nausea, upset stomach and stomach/abdominal cramping may occur; iron may cause stools to turn black, an effect that is not harmful. This product may interfere with certain laboratory tests (including testing for blood in stool), possibly causing false results - make sure laboratory personnel and all doctors know you are taking this product. Take a few hours before or after taking other medications or natural health products. Keep out of reach of children. There is enough drug in this package to seriously harm a child.
Indications
Recommended Use or Purpose: Helps to form red blood cells. Helps in energy metabolism. Helps to support normal early fetal development. Licensed Natural Health Product, NPN 80124890.
Ingredients
Medicinal Ingredients (per capsule): Vitamin C (PureWay-C - ascorbic acid) 50 mg, Iron (heme iron polypeptide) 11 mg, Citrus bioflavonoids 1 mg (fruit: Citrus aurantiifolia, Citrus limon, Citrus paradisi, Citrus reticulata, Citrus sinensis), Folate (L-5-methyltetrahydrofolate) 400 mcg, Vitamin B12 (methylcobalamin) 400 mcg. Non-medicinal ingredients: hypromellose, magnesium stearate, microcrystalline cellulose, rice bran oil. PureWay-C is a trademark of its respective owner. NMIs are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 19 years and older, including pregnant and breastfeeding women): Take 1 capsule per day. Take with food, a few hours before or after taking other medications or natural health products.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.