CanPrev GABA 500mg - Pure GABA Supplement | 120 V-Caps
Visit the CanPrev Store| Brand | CanPrev |
| Serving | 500 mg (1 capsule) |
| Licensed Natural Health Product | NPN 80102737 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- SUPPORTS RELAXATION - THE AUTHORIZED USE: CanPrev GABA 500's Health Canada license authorizes one clear use: helping to temporarily promote relaxation, from a 500 mg dose of pure gamma-aminobutyric acid per vegetable capsule.
- GABA IS A NATURAL, ENDOGENOUS NEUROTRANSMITTER: GABA (gamma-aminobutyric acid) is the brain's primary inhibitory neurotransmitter, naturally produced by the body to help calm neural activity.
- FLEXIBLE, LABEL-GUIDED DOSING: Adults take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner - use day or night, adjusting within the labelled range for your own routine.
- SIMPLE, FOCUSED FORMULA: 500 mg of GABA per vegetable capsule, with only vegetable-grade magnesium stearate and microcrystalline cellulose besides the capsule shell - no unnecessary fillers.
- VEGAN, NON-GMO & GLUTEN-FREE: A clean, allergen-conscious formula - vegan, non-GMO, gluten-free, dairy-free and soy-free, with no artificial colours, flavours or preservatives.
- MADE IN CANADA, LICENSED: Formulated and made in Canada as part of CanPrev's Pro Essentials line, licensed by Health Canada as a Natural Health Product, NPN 80102737.
Product Description
GABA 500 - Pure Gamma-Aminobutyric Acid for Relaxation
CanPrev GABA 500 delivers a 500 mg dose of pure gamma-aminobutyric acid (GABA) per vegetable capsule - a naturally occurring inhibitory neurotransmitter your body already makes. Helps to temporarily promote relaxation. A single-ingredient, vegan, non-GMO, gluten-free formula made in Canada. Licensed Natural Health Product NPN 80102737.
CanPrev GABA 500 offre une dose de 500 mg d'acide gamma-aminobutyrique (GABA) pur par capsule végétale - un neurotransmetteur inhibiteur naturellement présent dans l'organisme. Aide à promouvoir temporairement la relaxation. Une formule à ingrédient unique, végane, sans OGM et sans gluten, fabriquée au Canada. Produit de santé naturel homologué. NPN 80102737.
Pure GABA, 500 mg
Single-ingredient vegetable capsules - Vegan, Non-GMO, Gluten-Free
500 mg Per Capsule
A focused dose of gamma-aminobutyric acid in every vegetable capsule, with only two non-medicinal ingredients besides the capsule shell - no unnecessary fillers.
Flexible Dosing, 1 to 3 Capsules Daily
Take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner - adjust within the labelled range to suit your own routine, day or night.
What CanPrev GABA 500 Supports
GABA is the brain's main inhibitory neurotransmitter. Here's what the label and the research summarize about its role.
Relaxation
Helps to temporarily promote relaxation - the Health Canada-authorized use on this product's license.
Restful Nights
Formulated for use day or night; GABA's calming role has made it a widely studied ingredient for winding down in the evening.
Everyday Calm
A steady, single-ingredient way to support a sense of calm and ease mental tension during busy, demanding days.
Balance & Well-Being
Part of a routine aimed at maintaining overall calm and emotional balance alongside diet, sleep and stress management.
CanPrev GABA: Supplement Facts
Each Vegetable Capsule contains:
- Gamma-Aminobutyric Acid (GABA)500 mg
Non-Medicinal Ingredients: Vegetable-grade magnesium stearate, microcrystalline cellulose, vegetable capsule.
Recommended Use or Purpose: Helps to temporarily promote relaxation.
Recommended Dose (Adults): Take one (1) capsule, one (1) to three (3) times per day, or as directed by a health care practitioner. Recommended Duration of Use: For use beyond 4 weeks, consult a health care practitioner.
Cautions and Warnings: As with any natural health product, you should consult a health care practitioner prior to use, especially if you are pregnant or breastfeeding or if symptoms persist or worsen. Do not use with alcohol. Do not use if the safety seal is broken. Keep out of reach of children. Store in a cool, dry place.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Formulated and made in Canada by CanPrev Natural Health Products Ltd. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Chaque capsule végétale contient :
- Acide gamma-aminobutyrique (GABA)500 mg
Ingrédients non médicinaux : Stéarate de magnésium de grade végétal, cellulose microcristalline, capsule végétale.
Usage ou fins recommandés : Aide à promouvoir temporairement la relaxation.
Dose recommandée (adultes) : Prendre une (1) capsule, une (1) à trois (3) fois par jour, ou selon les indications d'un praticien de soins de santé. Durée d'utilisation recommandée : Consulter un praticien de soins de santé pour un usage de plus de 4 semaines.
Mises en garde et avertissements : Comme avec tout produit de santé naturel, vous devriez consulter un praticien de soins de santé avant d'en faire l'usage, surtout si vous êtes enceinte ou allaitez ou si les symptômes persistent ou s'aggravent. Ne pas consommer avec de l'alcool. Ne pas utiliser si le sceau de sécurité est brisé. Tenir hors de la portée des enfants. Conserver dans un endroit frais et sec.
NPN 80102737
Add CanPrev GABA 500 to your daily routine
Get CanPrev GABA 500 on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev GABA 500
A clean, single-ingredient neurotransmitter supplement in a simple vegetable capsule.
Single-ingredient focus
500 mg of pure gamma-aminobutyric acid per capsule, with only two non-medicinal ingredients besides the vegetable capsule shell.
The authorized relaxation claim
Health Canada licenses this product to help temporarily promote relaxation - a clear, verified use, not a vague wellness claim.
Flexible, vegetable-capsule dosing
1 to 3 capsules daily, day or night, lets you find the amount that works for your own routine.
Trusted Canadian brand
CanPrev - formulated and made in Canada, licensed under Health Canada NPN 80102737.
How to use it
Take 1 capsule, 1 to 3 times per day
Adults: take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner. Use day or night.
Swallow with water
Take the vegetable capsule whole with water. Do not exceed the recommended dose unless instructed by a health care practitioner.
Guided long-term use
Consult a health care practitioner for use beyond 4 weeks.
What the research says about GABA
Educational summaries of published research on gamma-aminobutyric acid (GABA) - including a real, ongoing scientific debate about how oral GABA acts in the body; these are not product-specific claims. CanPrev GABA 500's own claim is the authorized use under NPN 80102737: helping to temporarily promote relaxation.
Enhanced relaxation within an hour
In a human study, oral GABA increased relaxation-linked alpha-wave brain activity and reduced anxiety-linked beta-wave activity within about an hour of intake.
Human studyEased the mental strain of a stress task
In a randomized, placebo-controlled crossover trial, 100 mg of oral GABA reduced the EEG and mood changes normally triggered by a mental-arithmetic stress task, compared with placebo.
Human RCTA GABA-containing combination eased stress within a day
In a randomized trial of a nutraceutical combining GABA with another botanical extract, women reported measurable improvements in stress response and anxiety as early as day 1 - though the effect cannot be attributed to GABA alone in a combination formula.
Human RCTImproved sleep efficiency over 90 days
In a randomized, placebo-controlled trial, sedentary women taking 200 mg of GABA daily for 90 days alongside physical exercise showed improved habitual sleep efficiency, with lower Pittsburgh Sleep Quality Index scores versus placebo.
Human RCTA GABA and L-theanine combination improved sleep scores
In an exploratory study, adults with sleep problems taking combined GABA (700 mg/day) and L-theanine (200 mg/day) for 4 weeks saw their total Pittsburgh Sleep Quality Index score improve significantly, alongside wearable-tracked reductions in nighttime heart rate.
Human studySleep quality tracked in a 95-day human trial
A 95-day randomized trial of oral GABA (500 mg, three times daily) in adults included self-reported sleep quality among its secondary measures, one example of sleep being actively studied as an outcome of interest for oral GABA.
Human RCTA genuine, unresolved scientific debate
A widely cited review examines whether GABA and other neurotransmitters consumed as food supplements can meaningfully influence brain activity, given that GABA has long been thought unable to cross the blood-brain barrier in its free form - the authors conclude the mechanism is still far from clear.
ReviewPoor blood-brain-barrier crossing shapes new drug design
Pharmaceutical researchers note that GABA's low permeability through the blood-brain barrier and rapid gastrointestinal clearance are recognized limitations, which have directed research interest toward the gut-brain axis and enteric nervous system as possible alternate pathways of action.
MechanismGABA's roles reach beyond simple neuron-to-neuron signaling
GABA is also synthesized and released by glial cells (as a 'gliotransmitter'), a reminder that its signaling roles in the body are more complex than a single brain-crossing mechanism.
ReviewA human dose-escalation trial found it well tolerated
Adults given oral GABA in a controlled-release formulation at 200 mg, 600 mg and 1200 mg over an 11-day dose-escalation trial experienced no serious adverse events, with only a few mild, transient effects reported.
Human studyMonitored safely over 95 days at a higher daily dose
A 95-day trial giving adults 500 mg of oral GABA three times daily (1500 mg/day total) monitored safety throughout; the study's primary glucose-control outcome was not significantly different from placebo, an honest reminder that not every studied outcome shows an effect.
Human RCTNo safety concerns over 12 weeks of daily use
Healthy men taking 100 mg of GABA with whey protein daily for 12 weeks alongside resistance training completed the trial with elevated growth-hormone markers and no reported safety concerns from the combination.
Human RCTA 3-gram dose raised growth-hormone markers
In a randomized, double-blind, placebo-controlled crossover trial, resistance-trained men who ingested 3 grams of oral GABA showed elevated growth-hormone concentrations at rest and after exercise compared with placebo.
Human RCTA 100 mg dose changed brain-wave activity within 30 minutes
The same crossover trial measuring GABA's effect on a mental-arithmetic stress task pinpointed its EEG changes to about 30 minutes after a 100 mg capsule - a fraction of this product's 500 mg per-capsule dose.
Human RCTThe 600 mg dose point closest to this product produced a clear measured response
Within the same human dose-escalation trial, the 600 mg dose of oral GABA - the closest tested amount to this product's 500 mg per capsule - more than doubled the body's hormonal counter-regulatory response compared with no treatment.
Human studyGABA helps set the brake on the body's stress axis
A neuroscience review describes how GABA, glutamate and norepinephrine together regulate the corticotropin-releasing-hormone neurons that drive the hypothalamic-pituitary-adrenal (HPA) stress axis, with GABA supplying much of the inhibitory tone.
ReviewGut bacteria that make GABA may calm an overactive stress axis
A 2025 scoping review of gut microbial metabolites and depression found that GABA-producing gut bacteria are linked to suppressing hyperactivity of the hypothalamic-pituitary-adrenal (HPA) stress axis, alongside effects on synaptic plasticity.
ReviewA gut-nerve-brain network shapes the stress response
A narrative review describes how the vagus nerve and gut microbiota interact to modulate the HPA axis and neurotransmitter balance, including GABA, as part of an integrated stress-response and resilience network.
ReviewA researcher's 65-year account of how GABA earned its status
A neuroscientist's personal historical account traces how GABA came to be established as a genuine brain neurotransmitter, including the discovery that GABA is synthesized selectively within inhibitory neurons.
Historical reviewA concise history of GABA and glycine
A classic pharmacology review traces GABA's path from an obscure brain chemical, discovered just over 50 years ago, to the recognition that it now accounts for at least 40% of inhibitory synaptic processing in the mammalian brain.
ReviewCrustacean research proved GABA's inhibitory role
Early studies in crustacean nerve-muscle systems played a pivotal role in establishing that GABA functions as a major inhibitory neurotransmitter, after a period when leading scientists doubted GABA was a real neurotransmitter at all.
Historical reviewL-theanine, a related calming amino acid
A randomized, placebo-controlled crossover trial found an L-theanine-based nutrient drink reduced subjective and cortisol stress responses to a cognitive stressor, with brain-wave changes measured by magnetoencephalography.
Human RCTValerian root's evidence for sleep
A systematic review and meta-analysis of 60 studies found valerian root modestly effective for improving subjective sleep quality and reducing anxiety, one of the most-studied traditional calming botanicals.
Systematic reviewAshwagandha's stress, anxiety and sleep evidence
A randomized, double-blind, placebo-controlled trial of a standardized ashwagandha extract reported significant improvements in perceived stress, anxiety and sleep-quality scores over 84 days, with no safety concerns.
Human RCTFrequently asked questions
What is CanPrev GABA 500 and what does it do?
Gamma-aminobutyric acid (GABA) is the brain's main inhibitory neurotransmitter, naturally produced by the body. CanPrev GABA 500 provides 500 mg of pure GABA per vegetable capsule; its Health Canada-authorized use is to help temporarily promote relaxation.
How do I take CanPrev GABA 500?
Adults take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner. One 120-capsule bottle is a 120-day supply at the base dose of 1 capsule daily. Consult a health care practitioner for use beyond 4 weeks.
Can I take it during the day or only at night?
Either - the label directs 1 capsule, 1 to 3 times per day, with no requirement to take it only at bedtime, though many people use it in the evening to wind down.
Does oral GABA cross the blood-brain barrier?
This is a genuine, ongoing scientific question. GABA has limited ability to cross the blood-brain barrier in its free form, so researchers continue to study exactly how oral GABA produces its effects - possible pathways under study include the gut-brain axis and the enteric nervous system. CanPrev GABA 500's labelled claim (helping to temporarily promote relaxation) reflects its authorized use, not a specific mechanism claim.
Is it vegan and allergen-friendly?
Yes - vegan, non-GMO, gluten-free, dairy-free and soy-free, with no artificial colours, flavours or preservatives. Non-medicinal ingredients are limited to vegetable-grade magnesium stearate, microcrystalline cellulose and the vegetable capsule shell.
Who should not use it?
Consult a health care practitioner before use if you are pregnant or breastfeeding, or if symptoms persist or worsen. Do not use with alcohol. Do not use if the safety seal is broken.
Is it made in Canada?
Yes. CanPrev GABA 500 is formulated and made in Canada and licensed by Health Canada as a Natural Health Product under NPN 80102737.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Add CanPrev GABA 500 to your daily routine
Get CanPrev GABA 500 on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80102737. Helps to temporarily promote relaxation. The research summaries below concern the ingredient gamma-aminobutyric acid (GABA) generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use if you are pregnant or breastfeeding, or if symptoms persist or worsen. Do not use with alcohol. Consult a health care practitioner for use beyond 4 weeks. Results may vary.
Important information
Safety Information
Cautions and Warnings: As with any natural health product, you should consult a health care practitioner prior to use, especially if you are pregnant or breastfeeding or if symptoms persist or worsen. Do not use with alcohol. Do not use if the safety seal is broken. Keep out of reach of children. Store in a cool, dry place.
Indications
Recommended Use or Purpose: Helps to temporarily promote relaxation.
Ingredients
Medicinal Ingredients (1 Capsule): GABA (gamma-Aminobutyric acid) 500 mg. Non-medicinal Ingredients: Vegetable-grade magnesium stearate, microcrystalline cellulose, vegetable capsule. Vegan, non-GMO, gluten-free, dairy-free and soy-free; no artificial colours, flavours or preservatives.
Directions
Recommended Dose (Adults): Take one (1) capsule, one (1) to three (3) times per day, or as directed by a health care practitioner. Recommended Duration of Use: For use beyond 4 weeks, consult a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Formulated and made in Canada by CanPrev Natural Health Products Ltd. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.