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Health Canada NPN 80041704 30 Real Actives - NAC, Milk Thistle, Artichoke, Dandelion & ALA Vegetable Capsules · No Fillers · No Artificial Colours Made in Canada · One 15-Day Program per Bottle
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CanPrev Detox-Pro Formula - NAC, Milk Thistle & Artichoke | 90 Caps

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BrandCanPrev
Serving2 capsules (part of a 6-capsule/day, 15-day program)
Licensed Natural Health ProductNPN 80041704
Quality StandardsMade in Canada
CountryMade in Canada Made in Canada

About this item

  • A ONE-STEP, 15-DAY LIVER SUPPORT PROGRAM: Detox-Pro Formula is designed as a single, one-step 15-day program: take 2 capsules, 3 times per day with meals providing protein, then repeat periodically throughout the year as needed.
  • 30 REAL NUTRIENTS AND BOTANICALS IN EVERY CAPSULE: N-Acetyl-L-Cysteine (100 mg), milk thistle seed extract standardized to 80% silymarin, artichoke leaf extract, dandelion root extract, turmeric extract standardized to 95% curcuminoids, slippery elm and rosemary leaf extract, alongside DL-alpha lipoic acid and green tea extract.
  • LIPOTROPIC AMINO ACIDS - GLYCINE, TAURINE, L-METHIONINE & L-GLUTAMINE: A full complement of lipotropic amino acids to support the body's own processing of carbohydrates, fats and proteins, alongside choline.
  • A FULL B-COMPLEX, VITAMINS A, C & E, AND TRACE MINERALS: Every B vitamin (B1-B12, folate), vitamins A, C and E, plus zinc, selenium, copper, manganese and molybdenum, rounding out the formula's nutritional support during the 15-day program.
  • PROVIDES NUTRITIONAL FACTORS TO SUPPORT DETOXIFICATION PATHWAYS: Detox-Pro Formula's authorized use is to provide nutritional factors that support the body's own detoxification pathways and liver function.
  • CLEAN, VEGETABLE-CAPSULE FORMAT: No binders, no fillers, and no artificial colours, flavours or preservatives - just a hypromellose (vegetable) capsule and magnesium stearate.
  • PREMIUM CANADIAN QUALITY: Formulated and made in Canada by CanPrev, licensed under Health Canada NPN 80041704.

Customer Reviews

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Product Description

Detox-Pro Formula - 30 Real Actives for a One-Step, 15-Day Liver Support Program

CanPrev Detox-Pro Formula

A gentle, one-step 15-day program combining N-Acetyl-Cysteine, milk thistle, artichoke, dandelion root, alpha lipoic acid, slippery elm and L-glutamine with a full B-complex, lipotropic amino acids and trace minerals - 30 real nutrients and botanicals formulated to provide nutritional factors that support detoxification pathways and liver function. Licensed Natural Health Product NPN 80041704.

Un programme de détoxification en une seule étape, sur 15 jours, combinant la N-acétyl-cystéine, le chardon-Marie, l'artichaut, la racine de pissenlit, l'acide alpha-lipoïque, l'orme rouge et la L-glutamine avec un complexe B complet, des acides aminés lipotropes et des oligo-éléments - 30 nutriments et plantes réels conçus pour fournir des facteurs nutritionnels qui soutiennent les voies de détoxification et la fonction hépatique. Produit de santé naturel homologué. NPN 80041704.

Detox-Pro Formula lifestyle
CanPrev Detox-Pro Formula
30 Real Actives · NAC, Milk Thistle & Artichoke · 15-Day Liver Support

One Capsule, 30 Real Nutrients and Botanicals

NAC, Milk Thistle, Artichoke, Dandelion Root, ALA, Slippery Elm & L-Glutamine - Vegetable Capsules, No Fillers

A Genuine 30-Ingredient Liver Formula

Detox-Pro Formula combines N-Acetyl-Cysteine, milk thistle, artichoke, dandelion root, alpha lipoic acid, slippery elm, rosemary and green tea extract with a full B-complex, lipotropic amino acids and trace minerals - 30 real actives in every capsule, not a single-nutrient formula.

Built Around a One-Step, 15-Day Program

Take 2 capsules, 3 times per day with meals providing protein, for 15 days - a simple, single-step routine that may be repeated periodically throughout the year.

Advanced Ingredients, Superior Results

Detox-Pro Formula combines 30 real nutrients and botanicals - here is what several of its key actives are generally studied for.

N-Acetyl-L-Cysteine (NAC)

A precursor amino acid the body uses to help synthesize glutathione, one of its principal antioxidant and detoxification molecules.

100 mg per capsule

Milk Thistle Seed Extract (80% Silymarin)

Standardized to silymarin, milk thistle's best-studied active compound, traditionally used to support liver health.

33.3 mg per capsule

Artichoke Leaf Extract (4:1, Cynara scolymus)

A traditional bitter herb studied for antioxidant activity and support of healthy bile and liver function.

53 mg per capsule (equivalent to 212 mg dry leaf)

Dandelion Root Extract (10:1, Taraxacum officinale)

Used traditionally as a mild diuretic and choleretic (bile-stimulating) herb to support the liver's own cleansing processes.

16.7 mg per capsule (equivalent to 167 mg dry root)

Slippery Elm Extract (10:1, Ulmus fulva)

A traditional soothing herb included as part of Detox-Pro's comprehensive botanical blend.

16.7 mg per capsule (equivalent to 167 mg dry stem bark)

DL-Alpha Lipoic Acid

A fat- and water-soluble antioxidant studied for its ability to help recycle other cellular antioxidants.

16.7 mg per capsule

Turmeric Extract (95% Curcuminoids)

Standardized to curcuminoids, turmeric's principal active compounds, studied for antioxidant activity.

33.3 mg per capsule

Green Tea Extract (95% Polyphenols)

A polyphenol-rich extract studied for antioxidant activity; see the safety information for a rare but documented liver-injury caution associated with concentrated green tea extract.

20 mg per capsule

L-Glutamine

A conditionally essential amino acid the body uses to support cellular energy and general metabolic function.

50 mg per capsule

Lipotropic Amino Acids (Glycine, L-Methionine & Taurine)

Sulfur- and nitrogen-containing amino acids traditionally described as 'lipotropic' - supporting the body's processing of fats, carbohydrates and proteins.

41.7 mg each per capsule

Rosemary Leaf Extract (4:1, Rosmarinus officinalis)

An aromatic herb contributing additional polyphenol antioxidant activity to the formula.

16.7 mg per capsule (equivalent to 66.8 mg dry leaf)

Full B-Complex, Choline & Trace Minerals

A complete complement of B vitamins, additional antioxidant vitamins and trace mineral cofactors that round out the formula's nutritional support - see Supplement Facts for exact amounts.

Vitamins A, C, E, B1, B2, B3, B5, B6, B12, folate, choline, zinc, selenium, copper, manganese & molybdenum

CanPrev Detox-Pro Formula: Supplement Facts

CanPrev™Detox-Pro Formula
English

Supplement Facts

  • N-Acetyl-L-Cysteine (NAC) per capsule100 mg
  • Vitamin A (acetate) per capsule, 250 mcg RAE833 IU
  • Vitamin C (ascorbic acid) per capsule83.3 mg
  • Vitamin E (d-alpha tocopheryl acetate) per capsule, 67 IU44.6 mg AT
  • Vitamin B1 (thiamine HCl) per capsule8.34 mg
  • Vitamin B2 (riboflavin) per capsule8.34 mg
  • Vitamin B3 (niacin) per capsule8.34 mg
  • Vitamin B5 (calcium d-pantothenate) per capsule25 mg
  • Vitamin B6 (pyridoxal-5-phosphate) per capsule8.34 mg
  • Folate (folic acid) per capsule133 mcg
  • Vitamin B12 (methylcobalamin) per capsule167 mcg
  • Choline (choline bitartrate) per capsule10 mg
  • Copper (copper citrate) per capsule500 mcg
  • Magnesium (magnesium bisglycinate) per capsule8.34 mg
  • Manganese (manganese citrate) per capsule416.7 mcg
  • Molybdenum (sodium molybdate) per capsule8.35 mcg
  • Selenium (selenium yeast) per capsule33.3 mcg
  • Zinc (zinc citrate) per capsule5.0 mg
  • Glycine per capsule41.7 mg
  • L-Glutamine per capsule50 mg
  • L-Methionine per capsule41.7 mg
  • Taurine per capsule41.7 mg
  • DL-Alpha Lipoic Acid per capsule16.7 mg
  • Artichoke (leaf, Cynara scolymus) 4:1 extract, equiv. to 212 mg dry leaf per capsule53 mg
  • Turmeric (rhizome, Curcuma longa) extract, 95% curcuminoids per capsule33.3 mg
  • Dandelion (root, Taraxacum officinale) 10:1 extract, equiv. to 167 mg dry root per capsule16.7 mg
  • Green Tea (leaf, Camellia sinensis) extract, 95% polyphenols per capsule20 mg
  • Milk Thistle (seed, Silybum marianum) extract, 80% silymarin per capsule33.3 mg
  • Rosemary (leaf, Rosmarinus officinalis) 4:1 extract, equiv. to 66.8 mg dry leaf per capsule16.7 mg
  • Slippery Elm (stem bark, Ulmus fulva) 10:1 extract, equiv. to 167 mg dry stem bark per capsule16.7 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose (vegetable capsule), magnesium stearate. Contains soy. Free from GMO, binders, fillers, gluten, dairy, wheat, sugar, and artificial colours, flavours or preservatives.

Recommended Use or Purpose: Provides nutritional factors to support detoxification pathways and liver function.

Recommended Dose (Adults 19 years and older): Take 2 capsules, 3 times per day, with meals providing protein, a few hours before or after other medications or natural health products, or as directed by a qualified health care practitioner. Take for 15 days; may be repeated periodically throughout the year. For optimal results, take with plenty of fibre and probiotics, and avoid red meat, dairy, gluten, sugar and alcohol. No other vitamin supplements are needed during this time.

Cautions and Warnings: Do not use if you are pregnant, breastfeeding, taking antibiotics or nitroglycerin, allergic to plants of the Asteraceae/Compositae/Daisy family, or if you have a liver or gall bladder disorder, a bowel obstruction, or a bile duct obstruction. Ask a health care practitioner prior to use if you are taking any prescription medication, including antiplatelet medication or blood thinners. Ask a health care practitioner prior to use if you have gallstones, kidney stones, excess stomach acid, stomach ulcers, iron deficiency, cystinuria, diabetes, cancer, or a history of non-melanoma skin cancer. Because this product contains natural diuretics, ask a health care practitioner prior to use if you are taking products containing diuretics, or if you have heart disease, high or low blood pressure, a kidney disorder, or edema (swelling of the hands, face or feet). Ask a health care practitioner prior to use if you are following a low-protein diet. Ask a health care practitioner if symptoms persist or worsen. Stop use and seek medical attention immediately if you experience muscle weakness, pain, an abnormal heartbeat, or difficulty breathing. Stop use and consult a health care practitioner if you experience symptoms of serious low blood sugar such as sweating, paleness, chills, headache, dizziness, or confusion. Stop use and consult a health care practitioner if you develop symptoms of liver trouble such as yellowing of the skin or eyes (jaundice), stomach pain, dark urine, sweating, nausea, unusual tiredness, or loss of appetite. Hypersensitivity has been known to occur; in that case, discontinue use. People sensitive to niacin may experience mild, transient skin flushing. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported, in Canada and internationally. Contains soy. Do not use if the safety seal is broken. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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Fiche produit

  • N-acétyl-L-cystéine (NAC) par capsule100 mg
  • Vitamine A (acétate) par capsule, équivaut à 250 mcg ÉAR833 IU
  • Vitamine C (acide ascorbique) par capsule83.3 mg
  • Vitamine E (acétate de d-alpha-tocophéryle) par capsule, équivaut à 67 UI44.6 mg AT
  • Vitamine B1 (chlorhydrate de thiamine) par capsule8.34 mg
  • Vitamine B2 (riboflavine) par capsule8.34 mg
  • Vitamine B3 (niacine) par capsule8.34 mg
  • Vitamine B5 (d-pantothénate de calcium) par capsule25 mg
  • Vitamine B6 (pyridoxal-5-phosphate) par capsule8.34 mg
  • Folate (acide folique) par capsule133 mcg
  • Vitamine B12 (méthylcobalamine) par capsule167 mcg
  • Choline (bitartrate de choline) par capsule10 mg
  • Cuivre (citrate de cuivre) par capsule500 mcg
  • Magnésium (bisglycinate de magnésium) par capsule8.34 mg
  • Manganèse (citrate de manganèse) par capsule416.7 mcg
  • Molybdène (molybdate de sodium) par capsule8.35 mcg
  • Sélénium (levure de sélénium) par capsule33.3 mcg
  • Zinc (citrate de zinc) par capsule5.0 mg
  • Glycine par capsule41.7 mg
  • L-glutamine par capsule50 mg
  • L-méthionine par capsule41.7 mg
  • Taurine par capsule41.7 mg
  • Acide DL-alpha-lipoïque par capsule16.7 mg
  • Artichaut (feuille, Cynara scolymus) extrait 4:1, équivaut à 212 mg de feuille sèche par capsule53 mg
  • Curcuma (rhizome, Curcuma longa) extrait, 95% de curcumine par capsule33.3 mg
  • Pissenlit (racine, Taraxacum officinale) extrait 10:1, équivaut à 167 mg de racine sèche par capsule16.7 mg
  • Thé vert (feuille, Camellia sinensis) extrait, 95% de polyphénols par capsule20 mg
  • Chardon-Marie (graines, Silybum marianum) extrait, 80% de silymarine par capsule33.3 mg
  • Romarin (feuille, Rosmarinus officinalis) extrait 4:1, équivaut à 66.8 mg de feuille sèche par capsule16.7 mg
  • Orme rouge (écorce de tige, Ulmus fulva) extrait 10:1, équivaut à 167 mg d'écorce de tige sèche par capsule16.7 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose (capsule végétale), stéarate de magnésium. Contient du soya. Sans OGM, agents liants, agents de remplissage, gluten, produits laitiers, blé, sucre, ni colorants, arômes ou agents de conservation artificiels.

Usage ou fins recommandés : Fournit des facteurs nutritionnels afin de soutenir les voies de détoxification et les fonctions du foie.

Posologie recommandée (adultes de 19 ans et plus) : Prendre 2 capsules, 3 fois par jour, avec des repas contenant de la protéine, à quelques heures d'intervalle des autres médicaments ou produits de santé naturels, ou selon les directives d'un praticien de soins de santé qualifié. Prendre pendant 15 jours; peut être répété périodiquement pendant l'année. Pour des résultats optimaux, prendre avec beaucoup de fibres et de probiotiques, et éviter la viande rouge, les laitages, le gluten, le sucre et l'alcool. Aucun autre supplément vitaminique n'est nécessaire pendant cette période.

Mises en garde : Ne pas utiliser si vous êtes enceinte, si vous allaitez, si vous prenez des antibiotiques ou de la nitroglycérine, si vous êtes allergique aux plantes de la famille des Astéracées/Composées/Marguerites, ou si vous souffrez d'un trouble du foie ou de la vésicule biliaire, d'une obstruction des intestins, ou d'une obstruction des voies biliaires. Consulter un praticien de soins de santé avant l'usage si vous prenez tout médicament sur ordonnance, y compris des médicaments antiplaquettaires ou des anticoagulants. Consulter un praticien de soins de santé avant l'usage si vous souffrez de calculs biliaires, de calculs rénaux, d'un excès d'acide gastrique, d'ulcères gastriques, d'une carence en fer, d'une cystinurie, du diabète, du cancer, ou d'antécédents de cancer de la peau sans présence de mélanome. Parce que ce produit contient des diurétiques naturels, consulter un praticien de soins de santé avant l'usage si vous prenez des produits contenant des diurétiques, ou si vous souffrez d'une maladie du coeur, de basse ou de haute pression, de troubles rénaux, ou d'oedème (mains, visage ou pieds enflés). Consulter un praticien de soins de santé avant l'usage si vous suivez une diète faible en protéine. Consulter un praticien de soins de santé si les symptômes persistent ou s'aggravent. Cesser l'usage et consulter immédiatement un médecin si vous ressentez une faiblesse, une douleur musculaire, un rythme cardiaque anormal, ou des difficultés respiratoires. Cesser l'usage et consulter un praticien de soins de santé si vous manifestez des symptômes d'hypoglycémie grave tels que transpiration, pâleur, frissons, maux de tête, étourdissements, ou confusion. Cesser l'usage et consulter un praticien de soins de santé si vous développez des symptômes de troubles du foie tels que jaunissement de la peau ou des yeux (jaunisse), douleurs à l'estomac, urine foncée, transpiration, nausées, fatigue inhabituelle, ou perte d'appétit. En cas d'hypersensibilité, cesser l'utilisation. Les personnes sensibles à la niacine pourraient manifester des bouffées de chaleur légères et transitoires. Des cas imprévisibles rares de blessure au foie associée aux produits contenant un extrait de thé vert ont été rapportés, au Canada et internationalement. Contient du soya. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.

NPN 80041704

30 Real Actives · NAC, Milk Thistle & ArtichokeDandelion Root · ALA · Slippery Elm · L-Glutamine90 Vegetable Capsules · One 15-Day ProgramMade in Canada

Give your liver a 15-day, one-step reset

Get CanPrev Detox-Pro Formula on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev Detox-Pro Formula

A comprehensive, 30-active liver support formula built around a simple one-step, 15-day program - premium CanPrev quality, made in Canada.

30 real nutrients and botanicals

NAC, milk thistle, artichoke, dandelion root, alpha lipoic acid, slippery elm, rosemary, green tea extract, lipotropic amino acids, a full B-complex and trace minerals - all in one capsule.

One-step, 15-day program

A simple routine - 2 capsules, 3 times per day with meals providing protein, for 15 days - that may be repeated periodically throughout the year.

Provides nutritional factors to support detoxification pathways

Detox-Pro Formula is a licensed Natural Health Product authorized to provide nutritional factors that support the body's own detoxification pathways and liver function.

Premium Canadian brand

Formulated and made in Canada by CanPrev, in clean vegetable capsules with no binders or fillers. NPN 80041704.

Inside every capsule

30 real nutrients and botanicals - N-Acetyl-Cysteine, milk thistle, artichoke, dandelion root, alpha lipoic acid, slippery elm, L-glutamine, lipotropic amino acids, a full B-complex and trace minerals - in one 15-day, one-step liver support program.

N-Acetyl-L-Cysteine (NAC) 100 mg per capsuleMilk Thistle Seed Extract (80% Silymarin) 33.3 mg per capsuleArtichoke Leaf Extract (4:1, Cynara scolymus) 53 mg per capsule (equivalent to 212 mg dry leaf)Dandelion Root Extract (10:1, Taraxacum officinale) 16.7 mg per capsule (equivalent to 167 mg dry root)Slippery Elm Extract (10:1, Ulmus fulva) 16.7 mg per capsule (equivalent to 167 mg dry stem bark)DL-Alpha Lipoic Acid 16.7 mg per capsuleTurmeric Extract (95% Curcuminoids) 33.3 mg per capsuleGreen Tea Extract (95% Polyphenols) 20 mg per capsuleL-Glutamine 50 mg per capsuleLipotropic Amino Acids (Glycine, L-Methionine & Taurine) 41.7 mg each per capsuleRosemary Leaf Extract (4:1, Rosmarinus officinalis) 16.7 mg per capsule (equivalent to 66.8 mg dry leaf)Full B-Complex, Choline & Trace Minerals Vitamins A, C, E, B1, B2, B3, B5, B6, B12, folate, choline, zinc, selenium, copper, manganese & molybdenum

How to use it

Take 2 capsules, 3 times per day

Adults (19 years and older) take 2 capsules, 3 times per day, with meals providing protein, a few hours before or after taking other medications or natural health products.

For 15 days

Detox-Pro Formula is designed as a 15-day program. It may be repeated periodically throughout the year, or as directed by a qualified health care practitioner.

Support the program with fibre and probiotics

For optimal results, take with plenty of fibre and probiotics, and avoid red meat, dairy, gluten, sugar and alcohol during the 15-day program. No other vitamin supplements are needed during this time.

Check for interactions first

Do not use if pregnant, breastfeeding, taking antibiotics or nitroglycerin, or allergic to the Asteraceae/Compositae/Daisy plant family. Ask a health care practitioner first if you take prescription medication, blood thinners, or have gallstones, kidney stones, diabetes, heart disease, high/low blood pressure, a kidney disorder, or edema.

What the research says about Detox-Pro's ingredients

Educational summaries of published research on the individual ingredients in CanPrev Detox-Pro Formula; not product-specific claims. This product's own authorized claim is under NPN 80041704.

NAC & Glutathione / Liver Support

NAC reduced lipid droplets in a fatty-liver cell model

A 2024 study exposed HepG2 liver cells induced into a fatty-liver state to N-acetylcysteine, finding it increased fatty-acid beta-oxidation gene expression, reduced lipogenesis-related genes, and produced a dose-dependent reduction in lipid droplets.

Laboratory study
Gholamrezapour et al., Journal of Molecular Histology (2024)
NAC & Glutathione / Liver Support

Improved liver and pancreas damage scores after a toxic drug exposure

In rats given the chemotherapy drug l-asparaginase, subsequent N-acetylcysteine treatment produced a significant improvement in liver and pancreas damage scores compared with l-asparaginase alone.

Animal study
Yurttaş et al., Leukemia & Lymphoma (2022)
NAC & Glutathione / Liver Support

A 2023 study on NAC's role in hepatocyte glutathione balance

Research in human liver cancer cells describes N-acetylcysteine's central role in cellular glutathione redox regulation during a toxic drug exposure, while also noting that excessive NAC concentrations can shift that redox balance unfavourably - underscoring that dose matters for this antioxidant precursor.

Laboratory study
Aki et al., Biochemical and Biophysical Research Communications (2023)
Milk Thistle (Silymarin) & Liver Health

A meta-analysis of 55 trials found silymarin reduced liver enzymes

A meta-analysis of 55 randomized trials (3,545 patients) found silymarin administration significantly reduced AST and ALT levels, with the greatest reductions seen at lower doses and shorter treatment durations in patients with NAFLD or viral hepatitis.

Meta-analysis
Shahsavari et al., BMC Complementary Medicine and Therapies (2025)
Milk Thistle (Silymarin) & Liver Health

A placebo-controlled trial of a milk-thistle-containing formula reduced ALT

A phase II randomized, double-blind, placebo-controlled trial of milk thistle combined with Phyllanthus niruri in patients at risk for NASH found a significant reduction in ALT after 36 weeks in both the low-dose and high-dose groups.

Human RCT
Shaker et al., BMC Complementary Medicine and Therapies (2025)
Milk Thistle (Silymarin) & Liver Health

Reviewed as well-tolerated even at high doses

A safety and toxicity review describes silymarin, milk thistle's major constituent, as well tolerated in humans even at a high dose of 700 mg three times daily for 24 weeks, with its hepatoprotective effect well documented and only mild gastrointestinal effects reported.

Review
Soleimani et al., Phytotherapy Research (2019)
Artichoke Leaf Extract & Liver Function

A human pilot trial found artichoke leaf extract reduced liver steatosis

A randomized placebo-controlled pilot trial in prebariatric-surgery patients found artichoke leaf extract significantly reduced FibroScan-measured liver steatosis (CAP) and liver lobe diameter compared with placebo, with improvements evident after just 3 weeks.

Human RCT
Holländer et al., Journal of Clinical Lipidology (2025)
Artichoke Leaf Extract & Liver Function

Reduced oxidative and inflammatory markers after a toxic liver injury

In rats given the drug cyclophosphamide, an artichoke leaf extract reduced elevated malondialdehyde, TNF-alpha and IL-1beta while raising antioxidant markers, with histological examination showing markedly reduced liver damage versus untreated animals.

Animal study
Albayrak et al., Polish Journal of Veterinary Sciences (2025)
Artichoke Leaf Extract & Liver Function

Normalized liver enzymes after aflatoxin exposure in an animal model

Artichoke leaf powder given to rats exposed to the liver toxin aflatoxin B1 clearly reduced the toxin's adverse effects, normalizing most liver enzyme and antioxidant marker levels back toward control values.

Animal study
Nasef et al., Drug and Chemical Toxicology (2022)
Dandelion Root & Traditional Liver/Diuretic Use

A human pilot study found a real diuretic effect

A pilot clinical trial in human volunteers found a single-day dosing of dandelion leaf extract produced a significant increase in urinary frequency in the 5-hour period after the first dose, supporting its traditional use as a diuretic.

Human trial
Clare et al., Journal of Alternative and Complementary Medicine (2009)
Dandelion Root & Traditional Liver/Diuretic Use

Protected mouse liver tissue against a common drug toxin

Dandelion (Taraxacum officinale) leaf extract prevented the drop in liver antioxidant levels and the rise in liver enzymes caused by acetaminophen overdose in mice, with histopathology confirming reduced liver damage.

Animal study
Colle et al., Journal of Medicinal Food (2012)
Dandelion Root & Traditional Liver/Diuretic Use

A comprehensive review of dandelion's traditional and pharmacological uses

A review of Taraxacum's phytochemistry describes its long traditional use for liver and spleen complaints and hepatitis, and summarizes research supporting its diuretic, choleretic (bile-stimulating), and antioxidant effects.

Review
Schütz et al., Journal of Ethnopharmacology (2006)
Alpha Lipoic Acid & Antioxidant Recycling

Described as able to recycle other cellular antioxidants

A review of alpha lipoic acid's biochemistry describes its antioxidant activity as due to free-radical scavenging and its distinctive ability to recycle and enhance intracellular glutathione, as well as to chelate toxic metals.

Review
Tibullo et al., Inflammation Research (2017)
Alpha Lipoic Acid & Antioxidant Recycling

A meta-analysis of 4 trials found benefit for diabetic nerve symptoms

A meta-analysis of four randomized, placebo-controlled trials (1,258 patients) found 3 weeks of intravenous alpha-lipoic acid produced a clinically meaningful improvement in neuropathic symptom scores - including pain, burning and numbness - compared with placebo.

Meta-analysis
Ziegler et al., Diabetic Medicine (2004)
Alpha Lipoic Acid & Antioxidant Recycling

Reduced liver enzyme elevations from a toxic drug exposure

In rats given the chemotherapy drug cisplatin, alpha lipoic acid co-treatment decreased elevated liver enzymes (AST, ALT) and oxidative stress markers while increasing antioxidant enzyme levels, with reduced histological liver damage.

Animal study
Pınar et al., Biotechnic & Histochemistry (2019)
Curcumin (Turmeric) & Antioxidant/Liver Research

A meta-analysis of 52 studies found benefit across liver disease stages

A meta-analysis of 52 animal studies (792 animals) found curcumin significantly improved key markers across the progression from fatty liver disease to liver fibrosis to hepatocellular carcinoma, largely by reducing inflammatory markers.

Meta-analysis
Li et al., Frontiers in Pharmacology (2024)
Curcumin (Turmeric) & Antioxidant/Liver Research

Restored antioxidant defenses in liver cells after toxin exposure

A 2026 study found curcumin restored antioxidant enzyme activity and reduced DNA damage and apoptosis in human liver cells exposed to a persistent environmental toxin (a polychlorinated biphenyl).

Laboratory study
Erkekoğlu et al., Journal of Biochemical and Molecular Toxicology (2026)
Curcumin (Turmeric) & Antioxidant/Liver Research

Reviewed for hepatoprotective and anti-inflammatory effects

A review of curcumin's effects on lipid-related organ stress describes curcumin as a hydrophobic polyphenol used for its anti-inflammatory, antioxidant and hepatoprotective properties across multiple signaling pathways.

Review
Abolfazli et al., Journal of Pharmacy and Pharmacology (2024)
Green Tea Extract - A Documented Safety Signal

A case of acute liver failure linked to concentrated green tea extract

A case report describes an adolescent who developed acute impending liver failure while using a weight-loss product containing green tea extract, adding to a body of case reports raising concern about concentrated green tea extract specifically (as distinct from brewed tea).

Case report
Patel et al., World Journal of Gastroenterology (2013)
Green Tea Extract - A Documented Safety Signal

A case series of fat-burner supplements causing liver injury

A case series of four patients described liver injury - including one case requiring liver transplantation - associated with 'fat burner' supplements, one of which contained green tea extract as an ingredient.

Case series
Gavrić et al., Nutrition (2017)
Green Tea Extract - A Documented Safety Signal

A genetic risk marker identified in twin case reports

Monozygotic twins who developed jaundice and liver injury while taking a green-tea-extract-containing supplement both carried the HLA-B*35:01 allele, a known risk factor for green-tea-extract-induced liver injury.

Case reports
Sigurdarson et al., Journal of Clinical and Experimental Hepatology (2023)
Choline & Lipotropic Amino Acids

Choline deprivation causes organ dysfunction in most adults

A review on choline metabolism notes that when deprived of dietary choline, most adult men and postmenopausal women developed signs of organ dysfunction including fatty liver and liver or muscle cell damage, underscoring choline's essential, 'lipotropic' role in normal liver function.

Review
Zeisel, Brain Research (2008)
Choline & Lipotropic Amino Acids

Glycine studied as a protective nutrient for the liver

A review describes glycine as a therapeutic immuno-nutrient for liver disease, summarizing evidence that dietary glycine prevents activation of Kupffer cells (the liver's resident immune cells) and reduces inflammatory cytokine production implicated in liver injury.

Review
Yamashina et al., Alcoholism: Clinical and Experimental Research (2005)
Choline & Lipotropic Amino Acids

Taurine enhanced a sulfur amino acid's hepatoprotective effect

In mice given a toxic dose of acetaminophen, co-administering taurine alongside cystathionine (a cysteine-releasing compound) increased the hepatoprotective effect at low doses and helped restore liver glutathione levels that acetaminophen had depleted.

Animal study
Kitamura et al., Journal of Pharmacology and Experimental Therapeutics (1989)

Customer Reviews

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Frequently asked questions

What is CanPrev Detox-Pro Formula and what does it do?

It's a 30-ingredient liver support formula combining NAC, milk thistle, artichoke, dandelion root, alpha lipoic acid, slippery elm, rosemary and green tea extract with lipotropic amino acids, a full B-complex and trace minerals. It provides nutritional factors to support detoxification pathways and liver function.

How do I take it?

Adults 19 years and older take 2 capsules, 3 times per day with meals providing protein, for 15 days, a few hours before or after other medications. It may be repeated periodically throughout the year, or as directed by a qualified health care practitioner.

Is one bottle enough for the full program?

Yes. Each bottle contains 90 vegetable capsules - at 6 capsules per day (2 capsules, 3 times daily) that is exactly one 15-day program per bottle.

What should I avoid while using it?

For optimal results, avoid red meat, dairy, gluten, sugar and alcohol during the 15-day program, and take with plenty of fibre and probiotics. No other vitamin supplements are needed during this time.

Who should use caution, or not use it?

Do not use if you are pregnant, breastfeeding, taking antibiotics or nitroglycerin, allergic to plants of the Asteraceae/Compositae/Daisy family, or if you have a liver or gall bladder disorder, bowel obstruction, or bile duct obstruction. Because it contains natural diuretics, ask a health care practitioner first if you have heart disease, high or low blood pressure, a kidney disorder, or edema, or if you take prescription medication, antiplatelet medication, or blood thinners. Contains soy. Stop use and seek medical attention if you experience muscle weakness, pain, abnormal heartbeat, or difficulty breathing; stop use and consult a practitioner for signs of low blood sugar or liver trouble.

Does it contain vitamin B6 as pyridoxine HCl?

No - the licensed formula's vitamin B6 is pyridoxal-5-phosphate. Always check your own bottle's label for the exact ingredient panel and forms.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

30 Real Actives · NAC, Milk Thistle & ArtichokeDandelion Root · ALA · Slippery Elm · L-Glutamine90 Vegetable Capsules · One 15-Day ProgramMade in Canada

Give your liver a 15-day, one-step reset

Get CanPrev Detox-Pro Formula on Amazon.ca - fast, protected delivery.

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Natural Health Product NPN 80041704. Detox-Pro Formula provides nutritional factors to support detoxification pathways and liver function. The research summaries below concern the individual ingredients generally and are educational - they are not claims about this finished product. Read and follow the label. Do not use if you are pregnant, breastfeeding, taking antibiotics or nitroglycerin, allergic to plants of the Asteraceae/Compositae/Daisy family, or if you have a liver or gall bladder disorder, bowel obstruction, or bile duct obstruction. This product contains natural diuretics - consult a health care practitioner before use if you have heart disease, high or low blood pressure, a kidney disorder, or edema. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you are pregnant, breastfeeding, taking antibiotics or nitroglycerin, allergic to plants of the Asteraceae/Compositae/Daisy family, or if you have a liver or gall bladder disorder, a bowel obstruction, or a bile duct obstruction. Ask a health care practitioner prior to use if you are taking any prescription medication, including antiplatelet medication or blood thinners. Ask a health care practitioner prior to use if you have gallstones, kidney stones, excess stomach acid, stomach ulcers, iron deficiency, cystinuria, diabetes, cancer, or a history of non-melanoma skin cancer. Because this product contains natural diuretics, ask a health care practitioner prior to use if you are taking products containing diuretics, or if you have heart disease, high or low blood pressure, a kidney disorder, or edema (swelling of the hands, face or feet). Ask a health care practitioner prior to use if you are following a low-protein diet. Ask a health care practitioner if symptoms persist or worsen. Stop use and seek medical attention immediately if you experience muscle weakness, pain, an abnormal heartbeat, or difficulty breathing. Stop use and consult a health care practitioner if you experience symptoms of serious low blood sugar such as sweating, paleness, chills, headache, dizziness, or confusion. Stop use and consult a health care practitioner if you develop symptoms of liver trouble such as yellowing of the skin or eyes (jaundice), stomach pain, dark urine, sweating, nausea, unusual tiredness, or loss of appetite. Hypersensitivity has been known to occur; in that case, discontinue use. People sensitive to niacin may experience mild, transient skin flushing. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported, in Canada and internationally. Contains soy. Do not use if the safety seal is broken. Keep out of reach of children.

Indications

Recommended Use or Purpose: Provides nutritional factors to support detoxification pathways and liver function.

Ingredients

Medicinal ingredients (per capsule): N-Acetyl-L-Cysteine 100 mg, Vitamin A (acetate) 833 IU (250 mcg RAE), Vitamin C (ascorbic acid) 83.3 mg, Vitamin E (d-alpha tocopheryl acetate) 44.6 mg AT (67 IU), Vitamin B1 (thiamine HCl) 8.34 mg, Vitamin B2 (riboflavin) 8.34 mg, Vitamin B3 (niacin) 8.34 mg, Vitamin B5 (calcium d-pantothenate) 25 mg, Vitamin B6 (pyridoxal-5-phosphate) 8.34 mg, Folate (folic acid) 133 mcg, Vitamin B12 (methylcobalamin) 167 mcg, Choline (choline bitartrate) 10 mg, Copper (copper citrate) 500 mcg, Magnesium (magnesium bisglycinate) 8.34 mg, Manganese (manganese citrate) 416.7 mcg, Molybdenum (sodium molybdate) 8.35 mcg, Selenium (selenium yeast) 33.3 mcg, Zinc (zinc citrate) 5.0 mg, Glycine 41.7 mg, L-Glutamine 50 mg, L-Methionine 41.7 mg, Taurine 41.7 mg, DL-Alpha lipoic acid 16.7 mg, Artichoke (leaf, Cynara scolymus) 4:1 extract equivalent to 212 mg dry leaf 53 mg, Turmeric (rhizome, Curcuma longa) extract standardized to 95% curcuminoids 33.3 mg, Dandelion (root, Taraxacum officinale) 10:1 extract equivalent to 167 mg dry root 16.7 mg, Green tea (leaf, Camellia sinensis) extract standardized to 95% polyphenols 20 mg, Milk thistle (seed, Silybum marianum) extract standardized to 80% silymarin 33.3 mg, Rosemary (leaf, Rosmarinus officinalis) 4:1 extract equivalent to 66.8 mg dry leaf 16.7 mg, Slippery elm (stem bark, Ulmus fulva) 10:1 extract equivalent to 167 mg dry stem bark 16.7 mg. Non-medicinal ingredients: Hypromellose (vegetable capsule), magnesium stearate. Contains soy. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults 19 years and older): Take 2 capsules, 3 times per day, with meals providing protein, a few hours before or after other medications or natural health products, or as directed by a qualified health care practitioner. Take for 15 days; may be repeated periodically throughout the year. For optimal results, take with plenty of fibre and probiotics, and avoid red meat, dairy, gluten, sugar and alcohol. No other vitamin supplements are needed during this time.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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