CanPrev CoQ10 M.R.B. 100mg - Water-Soluble Ubiquinone | 60 Softgels
Visit the CanPrev Store| Brand | CanPrev |
| Serving | 1 softgel (1-3 daily) - 100mg Coenzyme Q10 (ubiquinone) |
| Licensed Natural Health Product | NPN 80009553 |
| Quality Standards | GMP-compliant facility |
| Made In | Made in USA  |
About this item
- THE ONLY WATER-SOLUBLE COQ10: 100mg of Coenzyme Q10 (ubiquinone) formulated using CanPrev's M.R.B. (Micellar Retention Bond) technology, making it water-soluble - unlike standard fat-soluble CoQ10 supplements.
- IDEAL FOR DIFFICULTY DIGESTING FATS: Because it is water-soluble, this formula is designed for those who have difficulty digesting fats, such as people without a gallbladder or with low stomach acid.
- SUPPORTS CARDIOVASCULAR HEALTH: Helps to support cardiovascular health - CoQ10 is a natural antioxidant the body produces less of as it ages.
- NATURALLY OCCURRING ANTIOXIDANT: CoQ10 is found in every cell of the body, concentrated in high-energy-demand organs like the heart, and can be taken as daily support and for preventative care.
- EASY-TO-SWALLOW SOFTGEL: A convenient softgel format, taken 1 to 3 times per day - simple to fit into a daily routine.
- CLEAN FORMULA: Non-GMO, gluten-free and dairy-free, made without artificial colours, flavours or preservatives. Contains soy.
- 60 SOFTGELS PER BOTTLE: At 1 softgel daily, one bottle provides up to a 60-day supply (fewer days if taken more than once daily).
- LICENSED NATURAL HEALTH PRODUCT: A Health Canada-licensed natural health product, NPN 80009553, from CanPrev's Pro Essentials line.
Product Description
CoQ10 M.R.B. 100 - The Only Water-Soluble CoQ10, for Cardiovascular Health
100mg of Coenzyme Q10 (ubiquinone) per softgel, formulated using CanPrev's M.R.B. (Micellar Retention Bond) technology - making it the only water-soluble form of CoQ10, designed for those who have difficulty digesting fats. Helps to support cardiovascular health. Licensed Natural Health Product NPN 80009553.
100 mg de coenzyme Q10 (ubiquinone) par gélule, formulé avec la technologie M.R.B. (Micellar Retention Bond) de CanPrev - en faisant la seule forme hydrosoluble de CoQ10, conçue pour les personnes ayant de la difficulté à digerer les graisses. Aide à soutenir la santé cardiovasculaire. Produit de santé naturel homologué. NPN 80009553.
Water-Soluble, Not Fat-Soluble
100mg Coenzyme Q10 (Ubiquinone) per Softgel - M.R.B. Technology, Non-GMO, Gluten-Free, Dairy-Free
The Only Water-Soluble CoQ10
Standard CoQ10 is fat-soluble and can be poorly absorbed; CanPrev's M.R.B. (Micellar Retention Bond) technology makes this formula water-soluble instead, designed for people who have difficulty digesting fats, such as those without a gallbladder or with low stomach acid.
A Real, Licensed Cardiovascular Claim
Licensed under NPN 80009553 to help support cardiovascular health - CoQ10 is a natural antioxidant the body produces less of as it ages, especially relevant for the heart's high energy demands.
What CanPrev CoQ10 M.R.B. Supports
Coenzyme Q10 is one of the most researched nutrients for heart and cellular energy - and its bioavailability depends heavily on how well it dissolves and absorbs. Here is what the wider research on CoQ10 and water-soluble formulations explores.
Cardiovascular Health
Helps to support cardiovascular health - the heart is one of the body's most energy-demanding organs, and CoQ10 is a key mitochondrial cofactor.
Enhanced Absorption via M.R.B.
CanPrev's M.R.B. technology makes this CoQ10 water-soluble, designed for those with difficulty digesting fats to still absorb this normally fat-soluble nutrient.
Antioxidant Protection
CoQ10 is a naturally occurring antioxidant, found in every cell of the body, that helps protect cells against the effects of free radicals.
Daily and Preventative Support
Natural CoQ10 production declines with age; this softgel can be taken as daily support and for preventative care.
CanPrev CoQ10 M.R.B. 100mg: Supplement Facts
Supplement Facts
- Coenzyme Q10 (ubiquinone) per softgel100 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: Annatto, gelatin, glycerin, hydroxylated lecithin (soy), medium chain triglycerides, polysorbate-80, purified water, sugars (sorbitol), sunflower oil, vitamin E.
Recommended Use or Purpose: Helps to support cardiovascular health.
Recommended Dose (Adults 18 years and older): Take 1 softgel, 1 to 3 times per day, or as directed by a health care practitioner.
Cautions and Warnings: Allergens: soy. Consult a healthcare practitioner prior to use if: you are pregnant; you are breastfeeding; you are taking blood pressure medications; you are taking blood thinners. Keep out of reach of children. Do not use if the safety seal is broken.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Fiche produit
- Coenzyme Q10 (ubiquinone) par gélule100 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : Annatto, eau purifiée, gélatine, glycérine, huile de tournesol, lécithine hydroxylée (soya), polysorbate-80, sucres (sorbitol), triglycérides à chaîne moyenne, vitamine E.
Usage ou fins recommandés : Aide à soutenir la santé cardiovasculaire.
Posologie recommandée (adultes de 18 ans et plus) : Prendre 1 gélule, 1 à 3 fois par jour, ou selon les directives d'un praticien de soins de santé.
Mises en garde et avertissements : Allergènes : soya. Consulter un praticien de soins de santé avant d'en faire l'usage si : vous êtes enceinte; vous allaitez; vous prenez des médicaments pour la tension artérielle; vous prenez des anticoagulants. Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé.
NPN 80009553
Support your heart with water-soluble CoQ10
Get CanPrev CoQ10 M.R.B. 100mg on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev CoQ10 M.R.B.
100mg of Coenzyme Q10, made water-soluble with M.R.B. technology - premium CanPrev quality.
The only water-soluble CoQ10
CanPrev's M.R.B. (Micellar Retention Bond) technology makes this normally fat-soluble nutrient water-soluble, designed for people who have difficulty digesting fats.
Built for compromised fat digestion
Ideal for those without a gallbladder or with low stomach acid, who may struggle to absorb standard fat-soluble CoQ10 supplements.
A real, licensed cardiovascular claim
NPN 80009553 authorizes this product to help support cardiovascular health - not just generic marketing language.
Clean, transparent formula
Non-GMO, gluten-free and dairy-free, made without artificial colours, flavours or preservatives. Contains soy. Licensed Natural Health Product, NPN 80009553.
How to use it
Take 1 softgel, 1 to 3 times per day
Adults (18 years and older): take 1 softgel, 1 to 3 times per day, or as directed by a health care practitioner.
No fat-containing meal required
Because this formula is water-soluble via M.R.B. technology, it does not depend on a fat-containing meal for absorption the way standard CoQ10 does.
Stay consistent daily
Take daily as part of your routine to support cardiovascular health and natural antioxidant levels that decline with age.
Store safely and check with a practitioner
Keep out of reach of children; do not use if the safety seal is broken. Consult a health care practitioner before use if pregnant, breastfeeding, taking blood pressure medication or blood thinners.
What the research says about water-soluble CoQ10 and Coenzyme Q10
Educational summaries of published research on Coenzyme Q10 generally, and on water-soluble/solubilized CoQ10 formulations specifically; not product-specific claims. CanPrev CoQ10 M.R.B.'s own authorized use under NPN 80009553 is that it helps to support cardiovascular health.
A water-soluble formulation raised cellular CoQ10 and boosted mitochondrial respiration
Comparing a hydrophilic (water-soluble) CoQ10 formulation against native CoQ10 in cultured cells, the water-soluble form was more efficient at raising ubiquinone levels, and higher intracellular CoQ10 content correlated with improved oxygen consumption, mitochondrial membrane potential and ATP synthesis.
Mechanistic studyStandard CoQ10's poor water solubility is the core delivery challenge
A translational review explains that CoQ10's clinical potential is constrained by poor water solubility and low oral bioavailability, and compares water-based delivery strategies (such as cyclodextrin complexation and solid dispersions) that enhance aqueous solubility and absorption versus traditional lipid-based approaches.
ReviewA solubilized CoQ10 formulation showed greater absorption without needing a fatty meal
In a randomized, double-blind, placebo-controlled crossover trial, a liposomal (solubilized) CoQ10 formulation achieved significantly higher peak plasma concentration and total absorption than standard unformulated CoQ10 - an approach studied specifically to improve absorption without depending on co-ingestion with fatty food.
Human RCTQ-SYMBIO: CoQ10 reduced major cardiovascular events in heart failure
In a 2-year, 420-patient randomized double-blind trial, CoQ10 100mg three times daily (added to standard heart-failure therapy) reduced the composite of major adverse cardiovascular events (15% vs 26%) plus cardiovascular and all-cause mortality compared with placebo.
Human RCTBenefit confirmed in the trial's European sub-population
A sub-group analysis of Q-SYMBIO's European patients confirmed CoQ10 significantly reduced major adverse cardiovascular events, all-cause and cardiovascular mortality and hospitalization, and found a significant improvement in left ventricular ejection fraction.
Human RCT sub-analysisA state-of-the-art review notes a relatively clean safety profile
Reviewing three decades of heart-failure research, this review describes CoQ10 as facilitating ATP production in the mitochondrial electron transport chain, highlights Q-SYMBIO's reduction in major adverse cardiovascular events, and notes CoQ10 is relatively safe with few drug interactions.
ReviewA 2025 meta-analysis of 45 trials found a systolic blood pressure reduction
Pooling 45 randomized trials, CoQ10 administration significantly reduced systolic blood pressure (by about 3.4 mmHg), with larger reductions at doses under 200mg/day and durations over 8 weeks, and no significant effect on diastolic blood pressure or heart rate.
Meta-analysisA dose-response analysis pinpoints 100-200mg/day as most effective
A dose-response meta-analysis of 26 studies found CoQ10 significantly reduced systolic blood pressure in people with cardiometabolic disorders, with a U-shaped dose-response relationship showing the largest benefit around 100-200mg/day.
Dose-response meta-analysisReduced both systolic and diastolic blood pressure in Type 2 diabetes
A systematic review and meta-analysis of 16 studies in patients with Type 2 diabetes found CoQ10 supplementation significantly reduced both systolic and diastolic blood pressure, with more pronounced effects at daily doses of 100mg or less.
Meta-analysisUbiquinone's central role shuttling electrons in the respiratory chain
A review describes ubiquinone (coenzyme Q) as a mobile component of the mitochondrial electron transport chain, essential to cellular energy metabolism, while also functioning as a membrane antioxidant.
ReviewFrom discovery to modern medical application
A historical review traces the discovery of ubiquinone (coenzyme Q) in mitochondrial research and its development from an electron and proton carrier to recognized antioxidant and prooxidant functions, and its application in medicine and nutrition.
Historical reviewCoQ shuttles electrons far beyond the classic energy-production role
A biochemistry review describes how Coenzyme Q, though best known for shuttling electrons between electron transport chain complexes, also serves as a cofactor for other biosynthetic and catabolic reactions and engages in cellular signaling.
ReviewA cellular pathway regenerates reduced CoQ to guard against oxidative damage
Researchers identified the FSP1-CoQ-NAD(P)H pathway, in which cells regenerate the reduced form of coenzyme Q to trap damaging lipid peroxyl radicals - part of the same redox system that shuttles electrons for mitochondrial energy production.
Mechanistic studyUbiquinol identified as the most active lipid-soluble antioxidant tested
Studying free radical oxidation in liver membrane phospholipids, this research found ubiquinol Q10 was the most active lipid-soluble natural antioxidant tested, and that suppressing its biosynthesis intensified lipid peroxidation in liver membranes and blood plasma.
Mechanistic studyCoQ10 is both a bioenergetic cofactor and an important antioxidant
A pharmacokinetics review describes coenzyme Q10's dual role in cellular energy production and as a lipid-soluble antioxidant, noting that its slow, limited natural absorption can be improved with better-formulated supplements.
ReviewStatins deplete isoprenoid compounds needed for healthy muscle, not just cholesterol
A review of statin-associated muscle toxicity explains that statins block an enzyme upstream in the same pathway that produces CoQ10 and other isoprenoids, implicating this broader depletion - not just lower muscle cholesterol - in statin-related muscle symptoms.
ReviewStatins measurably lower plasma CoQ10 via a shared biosynthetic pathway
A review explains that statins share a biosynthetic pathway with Coenzyme Q10, and that plasma CoQ10 levels are measurably lowered during statin treatment, with some evidence linking this depletion to subclinical cardiomyopathy that reverses with CoQ10 supplementation.
ReviewA 2025 meta-analysis found CoQ10 reduced statin-associated muscle pain
Pooling 7 randomized trials (389 patients) with CoQ10 doses of 100-600mg/day, this meta-analysis found a significant overall reduction in statin-associated muscle symptom pain intensity, though results varied across individual trials.
Meta-analysisCoQ10 well tolerated up to 900mg/day in healthy adults
A double-blind, randomized, placebo-controlled trial in 88 healthy adults found CoQ10 well tolerated at doses up to 900mg/day for 4 weeks, with no dose-related adverse events and no clinically significant changes in blood chemistry.
Human RCTHigh-dose RCT: adverse-event rates comparable to placebo
A randomized, placebo-controlled phase 2 trial of high-dose CoQ10 (1,500mg/day) in patients with multiple system atrophy reported adverse-event rates comparable between the CoQ10 group (23.8%) and placebo (30.9%), while significantly slowing disease progression on the primary outcome.
Human RCTA systematic review of coronary heart disease trials found CoQ10 appears safe
Reviewing recent randomized trials of CoQ10 in coronary heart disease and heart failure, this systematic review concludes CoQ10 appears to be safe, while noting current evidence does not support its routine use for blood pressure, cholesterol or glycemic control specifically.
Systematic reviewAbout 95% of circulating CoQ10 occurs as ubiquinol; solubilized forms absorb better
A review of oral CoQ10 formulations found plasma CoQ10 response increases with dose up to a plateau, that roughly 95% of circulating CoQ10 occurs as ubiquinol regardless of which form is ingested, and that solubilized CoQ10 formulations show superior bioavailability over standard tablets.
ReviewCoQ10 is the electron carrier that restores levels lowered by statins
A mitochondrial medicine review describes coenzyme Q10 as the electron carrier of the respiratory chain that generates ATP, and notes oral CoQ10 supplementation has been used to help restore plasma levels reduced by statin cholesterol-lowering drugs.
ReviewDose-dependent increases in plasma CoQ10 up to 200mg/day
Across several placebo-controlled trials, plasma CoQ10 rose in a dose-dependent manner up to a daily dose of 200mg (a roughly 6-fold increase at 200mg versus a marginal effect at the 30mg dose typically used in single-ingredient products), with the proportion in the reduced (ubiquinol) form increasing with supplementation.
Clinical studies reviewFrequently asked questions
What is CanPrev CoQ10 M.R.B. 100mg and what does it do?
It's a 100mg softgel dose of Coenzyme Q10 (ubiquinone), made water-soluble using CanPrev's M.R.B. (Micellar Retention Bond) technology. It helps to support cardiovascular health.
Is this ubiquinol or ubiquinone?
This product uses Coenzyme Q10 (ubiquinone) - the standard, oxidized form - made water-soluble via M.R.B. technology. It is not ubiquinol.
What does M.R.B. mean?
M.R.B. stands for Micellar Retention Bond - CanPrev's proprietary technology that makes this normally fat-soluble CoQ10 water-soluble, intended to enhance absorption and delivery.
Who is this formula designed for?
It's designed to be ideal for those with difficulty digesting fats, such as people without a gallbladder or with low stomach acid, who may not absorb standard fat-soluble CoQ10 supplements as well.
How do I take it?
Adults (18 years and older) take 1 softgel, 1 to 3 times per day, or as directed by a health care practitioner.
How long does one bottle last?
Each bottle contains 60 softgels - at the standard dose of 1 softgel daily, that's up to a 60-day supply (fewer days if taken more than once daily).
Is it vegan?
No - the softgel shell is made with gelatin, and the formula contains soy (hydroxylated lecithin). It is non-GMO, gluten-free and dairy-free.
Who should use caution, or not use it?
Consult a health care practitioner before use if you are pregnant, breastfeeding, taking blood pressure medication, or taking blood thinners. Keep out of reach of children and do not use if the safety seal is broken.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support your heart with water-soluble CoQ10
Get CanPrev CoQ10 M.R.B. 100mg on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80009553. Helps to support cardiovascular health. The research summaries below concern Coenzyme Q10 generally and water-soluble CoQ10 formulations, and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use, especially if you are pregnant, breastfeeding, taking blood pressure medication or blood thinners. Results may vary.
Important information
Safety Information
Cautions and Warnings: Allergens: soy. Consult a healthcare practitioner prior to use if: you are pregnant; you are breastfeeding; you are taking blood pressure medications; you are taking blood thinners. Keep out of reach of children. Do not use if the safety seal is broken.
Indications
Recommended Use or Purpose: Helps to support cardiovascular health.
Ingredients
Medicinal ingredient (per softgel): Coenzyme Q10 (ubiquinone) 100 mg. Non-medicinal ingredients: Annatto, gelatin, glycerin, hydroxylated lecithin (soy), medium chain triglycerides, polysorbate-80, purified water, sugars (sorbitol), sunflower oil, vitamin E. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults 18 years and older): Take 1 softgel, 1 to 3 times per day, or as directed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.