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Health Canada NPN 80031572 7 Real Actives: Andrographis, Reishi, Vitamin C, Echinacea, Astragalus, Ginseng, Zinc Vegan · No Fillers · No Artificial Colours Made in Canada · 90 Capsules, 22-Day Supply
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CanPrev Cold-Pro Immune Formula - 7 Herbs + Vitamin C | 90 Caps

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BrandCanPrev
Serving2 capsules (2 times per day)
Licensed Natural Health ProductNPN 80031572
Quality StandardsMade in Canada
CountryMade in Canada Made in Canada

About this item

  • EARLY SEASONAL SUPPORT: Take Cold-Pro at the first sign of infection to provide targeted botanical support - Andrographis and Echinacea work early, when timing matters most.
  • 7 REAL IMMUNE-SUPPORTING ACTIVES: 300mg Andrographis extract, Reishi mushroom, Vitamin C, Echinacea, Astragalus, American ginseng and Zinc in one vegan formula, with no fillers or artificial colours.
  • SUPPORTIVE THERAPY FOR RESPIRATORY INFECTIONS: Helps maintain immune system function, and helps relieve the symptoms and shorten the duration of upper respiratory tract infections.
  • SIMPLE TWICE-DAILY DOSE: Adults take 2 capsules, 2 times per day with food, at the first sign of infection - a 90-capsule bottle provides a 22-day supply.
  • CLEAN VEGAN FORMULA: Vegan, gluten-free vegetable capsules containing hypromellose and magnesium stearate as the only non-medicinal ingredients.
  • MADE IN CANADA: Formulated and made in Canada by CanPrev, licensed under Health Canada NPN 80031572.

Customer Reviews

4.6 out of 5 · 102 global ratings
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Product Description

Cold-Pro Immune Formula - 7 Immune-Supporting Actives

CanPrev Cold-Pro Immune Formula

A 7-ingredient formula combining 300mg Andrographis extract, Reishi mushroom, Vitamin C, Echinacea, Astragalus, American ginseng and Zinc - supportive therapy for upper respiratory tract infections that helps maintain immune function and shorten infection duration. Vegan, no fillers, no artificial colours. Licensed Natural Health Product NPN 80031572.

Une formule à 7 ingrédients combinant 300 mg d'extrait d'andrographis, du champignon reishi, de la vitamine C, de l'échinacée, de l'astragale, du ginseng américain et du zinc - une thérapie de soutien pour les infections des voies respiratoires supérieures qui aide à maintenir la fonction immunitaire et à raccourcir la durée de l'infection. Produit de santé naturel homologué. NPN 80031572.

Cold-Pro Immune Formula lifestyle
CanPrev Cold-Pro Immune Formula
300mg Andrographis · 7 Real Actives

Take at the First Sign of Infection

2 capsules, 2 times per day with food - 90 vegetable capsules, a 22-day supply

300mg Andrographis, Full Dose

A standardized 300mg dose of Andrographis extract (4:1, 4% andrographolides) per capsule - the formula's lead botanical for upper respiratory infection support.

7 Real Immune-Supporting Actives

Reishi mushroom, Vitamin C, Echinacea, Astragalus, American ginseng and Zinc join Andrographis in one vegan, filler-free formula.

Advanced Ingredients, Superior Results

Cold-Pro combines seven of the most researched botanicals and nutrients for immune support - here is what each ingredient is formulated to do.

Andrographis Extract (4:1)

A traditional botanical studied for supporting immune response and easing upper respiratory infection symptoms.

300 mg, standardized to 4% andrographolides

Reishi Mushroom Extract

A medicinal mushroom whose polysaccharides are studied for modulating immune cell activity.

100 mg, Ganoderma lucidum, 25% polysaccharides

Vitamin C

An essential antioxidant vitamin studied for reducing the duration and severity of the common cold.

100 mg, as ascorbic acid

Echinacea Root Extract (4:1)

A well-studied botanical traditionally used to help prevent and relieve upper respiratory tract infections.

87.5 mg, Echinacea purpurea

Astragalus Root Extract (4:1)

A traditional Chinese herb studied for supporting healthy immune cell function.

75 mg, Astragalus membranaceus

American Ginseng Root Extract (10:1)

A North American botanical studied for shortening cold duration and reducing respiratory infection frequency.

60 mg, Panax quinquefolius

Zinc

An essential trace mineral that supports the immune system's innate defense functions.

2.5 mg, as zinc citrate

CanPrev Cold-Pro Immune Formula: Supplement Facts

CanPrev™Cold-Pro Immune Formula
English

Product Facts

  • Andrographis extract 4:1, standardized to 4% andrographolides300 mg
  • Reishi mushroom extract Ganoderma lucidum, 25% polysaccharides100 mg
  • Vitamin C ascorbic acid100 mg
  • Echinacea root extract Echinacea purpurea, 4:187.5 mg
  • Astragalus root extract Astragalus membranaceus, 4:175 mg
  • American ginseng root extract Panax quinquefolius, 10:160 mg
  • Zinc as zinc citrate2.5 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Hypromellose, magnesium stearate, vegetable capsule.

Recommended Use or Purpose: Supportive therapy for the treatment of upper respiratory tract infections. Helps to maintain immune system function. Helps to relieve the symptoms and shorten the duration of respiratory tract infections.

Recommended Dose (Adults 19 years and older): Take 2 capsules, 2 times per day with food. Take at the first sign of infection, a few hours before or after taking other medications. Ask a healthcare practitioner for use beyond 2 months or if symptoms persist.

Cautions and Warnings: Do not use if you are pregnant, breastfeeding, have a bleeding disorder, have gastric hyperacidity such as duodenal ulcers, have oesophageal reflux, or have an allergy to reishi mushroom, echinacea or any member of the Asteraceae/Compositae/Daisy family. Ask a healthcare practitioner prior to use if you are taking any medication including immunosuppressants, digoxin or blood thinners. Ask a healthcare practitioner prior to use if you have a medical condition including diabetes, an autoimmune disorder, or a progressive systemic disease such as tuberculosis, leukosis, collagenosis or multiple sclerosis, or if symptoms persist or worsen. Hypersensitivity to echinacea and reishi mushroom has been known to occur, in which case discontinue use. Some people may experience diarrhea, nausea and skin irritations. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

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Info-produit

  • Extrait d'andrographis 4:1, normalisé à 4% d'andrographolides300 mg
  • Extrait de champignon reishi Ganoderma lucidum, 25% de polysaccharides100 mg
  • Vitamine C acide ascorbique100 mg
  • Extrait de racine d'échinacée Echinacea purpurea, 4:187.5 mg
  • Extrait de racine d'astragale Astragalus membranaceus, 4:175 mg
  • Extrait de racine de ginseng américain Panax quinquefolius, 10:160 mg
  • Zinc sous forme de citrate de zinc2.5 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Hypromellose, stéarate de magnésium, capsule végétale.

Usage ou fins recommandés : Thérapie de soutien pour le traitement des infections des voies respiratoires supérieures. Aide à maintenir la fonction du système immunitaire. Aide à soulager les symptômes et à raccourcir la durée des infections des voies respiratoires.

Dose recommandée (adultes de 19 ans et plus) : Prendre 2 capsules, 2 fois par jour avec de la nourriture. Prendre dès les premiers signes d'infection, quelques heures avant ou après la prise d'autres médicaments. Consultez un praticien de la santé pour un usage de plus de 2 mois ou si les symptômes persistent.

Mises en garde et précautions : Ne pas utiliser si vous êtes enceinte ou allaitante, si vous souffrez d'un trouble hémostatique, d'une hyperacidité gastrique telles que des ulcères duodénaux ou un reflux gastro-œsophagien, ou en cas d'allergie au champignon reishi, à l'échinacée ou à tout membre de la famille des Astéracées/Composées/Marguerites. Comme pour tout produit de santé naturel, consultez un praticien de soins de santé concernant l'utilisation de ce produit, surtout si vous prenez tout médicament incluant des immunosuppresseurs, la digoxine ou des anticoagulants, ou si vous souffrez d'un état médical incluant le diabète, un trouble auto-immun ou une maladie systémique progressive telle que la tuberculose, la leucose, la collagénose ou la sclérose en plaques, ou si les symptômes persistent ou s'aggravent. Une hypersensibilité à l'échinacée et au champignon reishi a été rapportée; le cas échéant, cessez l'utilisation. Certaines personnes peuvent ressentir de la diarrhée, des nausées ou des irritations cutanées. Garder hors de la portée des enfants.

NPN 80031572

300mg Andrographis · 7 Real ActivesSupportive Therapy for Respiratory Infections90 Capsules · 22-Day SupplyMade in Canada

Support your immune system at the first sign of infection

Get CanPrev Cold-Pro Immune Formula on Amazon.ca - fast, protected delivery.

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Why CanPrev Cold-Pro Immune Formula

7 real immune-supporting actives in one vegan formula, led by a full 300mg dose of Andrographis - premium CanPrev quality.

300mg Andrographis, the lead active

A standardized 300mg dose of Andrographis extract (4:1, 4% andrographolides) - the formula's best-researched botanical for upper respiratory infection support.

Supportive therapy for respiratory infections

Helps maintain immune system function and helps relieve symptoms and shorten the duration of upper respiratory tract infections.

7 real actives, no fillers

Reishi, Vitamin C, Echinacea, Astragalus, American ginseng and Zinc join Andrographis - a clean, vegan, filler-free formula.

Premium Canadian brand

CanPrev, formulated and made in Canada. NPN 80031572.

Inside every capsule

300 mg Andrographis extract plus Reishi mushroom, Vitamin C, Echinacea, Astragalus, American ginseng and Zinc - 7 real actives in one vegan capsule, no fillers.

Andrographis Extract (4:1) 300 mg, standardized to 4% andrographolidesReishi Mushroom Extract 100 mg, Ganoderma lucidum, 25% polysaccharidesVitamin C 100 mg, as ascorbic acidEchinacea Root Extract (4:1) 87.5 mg, Echinacea purpureaAstragalus Root Extract (4:1) 75 mg, Astragalus membranaceusAmerican Ginseng Root Extract (10:1) 60 mg, Panax quinquefoliusZinc 2.5 mg, as zinc citrate

How to use it

Take 2 capsules, twice daily

Adults (19 years and older) take 2 capsules, 2 times per day with food.

Start at the first sign of infection

Take at the first sign of infection, a few hours before or after taking other medications.

Ask a professional beyond 2 months

For use beyond 2 months, or if symptoms persist, ask a healthcare practitioner.

Watch for hypersensitivity

Discontinue use and consult a health care practitioner if you experience hypersensitivity, diarrhea, nausea or skin irritation.

What the research says about Cold-Pro's ingredients

Educational summaries of published research on the individual ingredients in this formula - not claims about this finished product. CanPrev Cold-Pro Immune Formula's claim is the authorized use under NPN 80031572.

Andrographis & Upper Respiratory Infection

Systematic review across 7 trials in nearly 900 patients

A systematic review of double-blind trials found that Andrographis paniculata was superior to placebo in relieving the subjective symptoms of uncomplicated upper respiratory tract infection, with preliminary evidence of a preventive effect and generally mild, infrequent adverse events.

Systematic review
Coon & Ernst, Planta Medica (2004)
Andrographis & Upper Respiratory Infection

Phase III trial improved cold symptom scores by Day 3

In a 300-person phase III randomized, double-blind, placebo-controlled trial, a standardized Andrographis paniculata extract significantly lowered WURSS-21 global symptom scores versus placebo by day 3 of a common cold, at both tested doses.

Human RCT, Phase III
Raj et al., Complementary Therapies in Medicine (2023)
Andrographis & Upper Respiratory Infection

Faster symptom resolution for sore throat

In a randomized, double-blind trial of adults with acute viral pharyngitis, an Andrographis paniculata spray resolved sore throat, swallowing difficulty and cough more quickly than a positive-control spray, with no adverse events in either group.

Human RCT
Okonogi et al., Drug Discoveries & Therapeutics (2023)
Reishi Mushroom & Immune Modulation

A well-characterized immune-modulating mechanism

A review of Ganoderma lucidum polysaccharides describes extensive immunomodulating effects, including promoting the function of antigen-presenting cells, natural killer cells, and both humoral and cellular immunity.

Review
Lin, Journal of Pharmacological Sciences (2005)
Reishi Mushroom & Immune Modulation

Increased immune cell counts in a pediatric RCT

In a randomized, double-blind, placebo-controlled trial in children aged 3 to 5, a beta-glucan preparation from Ganoderma lucidum significantly increased circulating CD3+, CD4+ and CD8+ T lymphocyte counts versus placebo, and was safe and well tolerated.

Human RCT
Henao et al., International Journal of Medicinal Mushrooms (2018)
Reishi Mushroom & Immune Modulation

Enhanced antibody and T-cell responses as a mucosal adjuvant

In an animal model, a Ganoderma lucidum polysaccharide used as a mucosal vaccine adjuvant generated significantly higher neutralizing antibody levels and stronger T-cell cytokine responses against a respiratory viral pathogen.

Preclinical study
Lin et al., Frontiers in Immunology (2020)
Vitamin C & Common Cold Duration

Cochrane review: shorter colds with regular supplementation

A Cochrane meta-analysis of 29 trial comparisons in over 11,000 participants found that regular vitamin C supplementation reduced common cold duration by 8% in adults and 14% in children, and halved cold risk in people under brief periods of severe physical stress.

Meta-analysis
Hemila & Chalker, Cochrane Database of Systematic Reviews (2013)
Vitamin C & Common Cold Duration

Reanalysis found a 21% reduction in cold duration

A reanalysis of seven placebo-controlled studies found that vitamin C (1-6 g/day) decreased the duration of cold episodes by nearly a full day on average, a 21% relative reduction, correcting methodological gaps in an earlier influential review.

Meta-analysis
Hemila & Herman, Journal of the American College of Nutrition (1995)
Vitamin C & Common Cold Duration

Larger benefit under physical stress exposure

A Cochrane meta-analysis found that among marathon runners, skiers and soldiers on subarctic exercises, regular vitamin C supplementation roughly halved the risk of developing a cold compared with the general population.

Meta-analysis
Douglas et al., Cochrane Database of Systematic Reviews (2007)
Echinacea & Respiratory Tract Infections

Fewer infections and 76% fewer antibiotic courses in children

In a randomized, blinded, controlled trial in children aged 4 to 12, an Echinacea purpurea extract prevented 32.5% of respiratory tract infection episodes and reduced antibiotic treatment courses by 76.3% compared with a vitamin C control.

Human RCT
Ogal et al., European Journal of Medical Research (2021)
Echinacea & Respiratory Tract Infections

Meta-analysis found a preventive effect on infection risk

A systematic review and meta-analysis of randomized, placebo-controlled trials found a risk ratio of 0.78 for the prevention of upper respiratory tract infection with Echinacea preparations, with no evidence of increased safety risk in the short term.

Meta-analysis
David & Cunningham, Complementary Therapies in Medicine (2019)
Echinacea & Respiratory Tract Infections

Lower risk of a second infection in children

In a randomized, double-blind, placebo-controlled trial in 524 children, those who took Echinacea purpurea for an initial respiratory infection had a 28% lower risk of developing a subsequent infection during the same season.

Human RCT
Weber et al., Journal of Alternative and Complementary Medicine (2005)
Astragalus & Immune Function

Rapid T-cell activation, additive in combination

In a human pilot study, orally ingested Echinacea, Astragalus and Glycyrrhiza herbal tinctures each activated CD4 and CD8 T cells (measured by CD69 expression) within 24 hours, with an additive effect when the herbs were combined.

Human pilot study
Brush et al., Phytotherapy Research (2006)
Astragalus & Immune Function

A dedicated trial measuring natural killer cell activity

A registered randomized, double-blind, placebo-controlled trial protocol is evaluating an Astragalus membranaceus-based compound for improving natural killer cell activity and respiratory symptoms in adults with a history of recurrent upper respiratory infections.

Human RCT protocol
Cheon & Ko, BMC Complementary Medicine and Therapies (2025)
Astragalus & Immune Function

Improved T-cell markers of immune function

A randomized trial found that Astragalus membranaceus significantly increased the CD4 T-cell level and CD4/CD8 ratio, a marker of improved cellular immune function, in patients receiving it as an adjunct treatment.

Human RCT
Liu et al., Chinese Journal of Integrated Traditional and Western Medicine (2003)
American Ginseng & Cold Prevention

Fewer colds and shorter symptom duration over 4 months

In a randomized, double-blind, placebo-controlled trial of 323 adults with a history of frequent colds, a North American ginseng extract reduced the mean number of colds per person and the total number of days with cold symptoms over a 4-month period.

Human RCT
Predy et al., CMAJ (2005)
American Ginseng & Cold Prevention

89% relative risk reduction in older adults

In two placebo-controlled trials in institutionalized older adults, a proprietary North American ginseng extract reduced laboratory-confirmed influenza and respiratory syncytial virus illness by an overall 89% relative risk reduction versus placebo.

Human RCT
McElhaney et al., Journal of the American Geriatrics Society (2004)
American Ginseng & Cold Prevention

Systematic review: shortened cold duration by over 6 days

A systematic review of North American and Asian ginseng trials found that, while evidence for reducing cold incidence was inconsistent, North American ginseng significantly shortened the duration of colds or acute respiratory infections when taken preventively for 8 to 16 weeks.

Systematic review
Seida et al., Evidence-Based Complementary and Alternative Medicine (2011)
Zinc & Immune Defense

Cochrane review: shortened duration of cold symptoms

A Cochrane meta-analysis of therapeutic trials found that zinc intake was associated with a significant reduction in the duration of common cold symptoms when taken within 24 hours of symptom onset.

Meta-analysis
Singh & Das, Cochrane Database of Systematic Reviews (2013)
Zinc & Immune Defense

Systematic review: colds shortened by over 2 days

A systematic review of randomized controlled trials on single-nutrient supplementation found that zinc, unlike most other micronutrients tested, reduced common cold duration by an average of 2.25 days in healthy adults.

Systematic review
Wang et al., The American Journal of Tropical Medicine and Hygiene (2020)
Zinc & Immune Defense

An established role in innate immune defense

A review of zinc and vitamin C's roles in immune function describes zinc's importance for phagocytosis, natural killer cell activity and oxidative burst, citing randomized trials showing adequate zinc intake ameliorates symptoms and shortens the duration of respiratory tract infections including the common cold.

Review
Wintergerst et al., Annals of Nutrition & Metabolism (2005)
Combination Immune Formulas: Research & Safety

A clinical review spanning four of this formula's ingredients

A clinical review of complementary approaches to the common cold found supporting evidence for vitamin C in prevention and for Echinacea purpurea and zinc lozenges in treatment, with ginseng noted as warranting further research.

Clinical review
Nahas & Balla, Canadian Family Physician (2011)
Combination Immune Formulas: Research & Safety

A different multi-botanical blend reduced infections and modulated immunity

In a randomized, double-blind, placebo-controlled trial of a different multi-botanical blend for upper respiratory tract infections, the combination significantly reduced infection incidence and throat symptoms while modulating cytokine production in immune cells - illustrating the research basis for combination herbal immune formulas generally.

Human RCT
Zima et al., International Journal of Molecular Sciences (2024)
Combination Immune Formulas: Research & Safety

Andrographis: serious adverse events very rare

A systematic review and meta-analysis of Andrographis paniculata safety data found the pooled incidence of serious adverse events was extremely rare, with most reported adverse events being mild gastrointestinal or skin-related.

Meta-analysis
Worakunphanich et al., Pharmacoepidemiology and Drug Safety (2021)

Customer Reviews

4.6 out of 5 · 102 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

What is CanPrev Cold-Pro Immune Formula and what does it do?

It's a 7-ingredient formula (Andrographis, Reishi mushroom, Vitamin C, Echinacea, Astragalus, American ginseng and Zinc) formulated as supportive therapy for upper respiratory tract infections. It helps maintain immune system function and helps relieve symptoms and shorten infection duration.

How do I take it?

Adults 19 years and older take 2 capsules, 2 times per day with food. Take at the first sign of infection, a few hours before or after other medications. Ask a healthcare practitioner for use beyond 2 months or if symptoms persist.

How long does one bottle last?

Each bottle contains 90 vegetable capsules - at the recommended dose of 2 capsules twice daily, that's a 22-day supply.

Is it vegan?

Yes - the formula and vegetable capsule are vegan, with no fillers or artificial colours. Non-medicinal ingredients are hypromellose and magnesium stearate.

Who should use caution, or not use it?

Do not use if you are pregnant or breastfeeding, have a bleeding disorder, gastric hyperacidity such as duodenal ulcers or oesophageal reflux, or an allergy to reishi mushroom, echinacea or any member of the Asteraceae/daisy family. Ask a health care practitioner before use if you take immunosuppressants, digoxin or blood thinners, or have diabetes, an autoimmune disorder, or a progressive systemic disease such as tuberculosis, leukosis, collagenosis or multiple sclerosis. Some people may experience diarrhea, nausea or skin irritation.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

300mg Andrographis · 7 Real ActivesSupportive Therapy for Respiratory Infections90 Capsules · 22-Day SupplyMade in Canada

Support your immune system at the first sign of infection

Get CanPrev Cold-Pro Immune Formula on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80031572. Supportive therapy for the treatment of upper respiratory tract infections. Helps to maintain immune system function. Helps to relieve the symptoms and shorten the duration of respiratory tract infections. The research summaries below concern the ingredients generally and are educational - they are not claims about this finished product. Read and follow the label. Do not use if you are pregnant or breastfeeding, have a bleeding disorder, gastric hyperacidity such as duodenal ulcers or oesophageal reflux, or an allergy to reishi mushroom, echinacea or any member of the Asteraceae/daisy family. Ask a health care practitioner before use if taking immunosuppressants, digoxin or blood thinners, or if you have diabetes, an autoimmune disorder, or a progressive systemic disease such as tuberculosis, leukosis, collagenosis or multiple sclerosis. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you are pregnant, breastfeeding, have a bleeding disorder, have gastric hyperacidity such as duodenal ulcers, have oesophageal reflux, or have an allergy to reishi mushroom, echinacea or any member of the Asteraceae/Compositae/Daisy family. Ask a healthcare practitioner prior to use if you are taking any medication including immunosuppressants, digoxin or blood thinners. Ask a healthcare practitioner prior to use if you have a medical condition including diabetes, an autoimmune disorder, or a progressive systemic disease such as tuberculosis, leukosis, collagenosis or multiple sclerosis, or if symptoms persist or worsen. Hypersensitivity to echinacea and reishi mushroom has been known to occur, in which case discontinue use. Some people may experience diarrhea, nausea and skin irritations. Keep out of reach of children.

Indications

Recommended Use or Purpose: Supportive therapy for the treatment of upper respiratory tract infections. Helps to maintain immune system function. Helps to relieve the symptoms and shorten the duration of respiratory tract infections.

Ingredients

Medicinal Ingredients (per capsule): Andrographis extract (4:1, standardized to 4% andrographolides) 300 mg. Reishi mushroom extract (Ganoderma lucidum, standardized to 25% polysaccharides) 100 mg. Vitamin C (ascorbic acid) 100 mg. Echinacea root extract (Echinacea purpurea, 4:1) 87.5 mg. Astragalus root extract (Astragalus membranaceus, 4:1) 75 mg. American ginseng root extract (Panax quinquefolius, 10:1) 60 mg. Zinc (as zinc citrate) 2.5 mg. Non-medicinal ingredients: Hypromellose, magnesium stearate, vegetable capsule. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults 19 years and older): Take 2 capsules, 2 times per day with food. Take at the first sign of infection, a few hours before or after taking other medications. Ask a healthcare practitioner for use beyond 2 months or if symptoms persist.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

$24.99 CAD4.6 ★ (102) Get it on Amazon →