Available at Amazon
Health Canada NPN 80129261 275mg VitaCholine (Choline L(+) Bitartrate) per capsule Vegan · Non-GMO · Gluten-free Made in Canada · GMP facility
CholineCholine - benefits and key ingredients Choline - lifestyleCholine - ingredientsCholine - supplement facts panel

CanPrev Choline 275mg - VitaCholine, Liver Function Support | 90 Caps

Visit the CanPrev Store

$26.13 CAD ($0.29 / capsule)
Get it on Amazon.ca
BrandCanPrev
Serving1 capsule (1-3 times daily)
Licensed Natural Health ProductNPN 80129261
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • BIOAVAILABLE CHOLINE SOURCE: Each vegetable capsule delivers 275 mg of VitaCholine, a well-studied, fast-dissolving form of choline, in a clean vegan format.
  • LICENSED TO SUPPORT LIVER FUNCTION: Health Canada NPN 80129261 licenses this product to help support liver function - choline's core recognized role in the body's fat and nutrient metabolism.
  • AN ESSENTIAL, OFTEN-MISSED NUTRIENT: Choline is classified as an essential nutrient involved in cell-membrane structure and the production of the neurotransmitter acetylcholine, yet most adults do not meet recommended intake from diet alone.
  • SIMPLE, FLEXIBLE DOSING: Adolescents and adults (9 years and older) take 1 capsule, 1 to 3 times per day - a 90-capsule bottle covers up to a 90-day supply at the base dose.
  • CLEAN CANADIAN FORMULA: Made in Canada, each vegetable capsule is free from GMOs, gluten, dairy, soy, wheat, yeast, sugar and preservatives.
  • MADE IN CANADA, LICENSED: Manufactured in Canada in a GMP-compliant facility and licensed by Health Canada as a Natural Health Product, NPN 80129261.

Product description

One essential nutrient, licensed to help support liver function

CanPrev Choline

A closer look at CanPrev Choline 275 - 275 mg of VitaCholine (choline L(+) bitartrate) per capsule, made in Canada. Licensed Natural Health Product NPN 80129261.

Choline lifestyle
CanPrev Choline
275mg VitaCholine (Choline Bitartrate) · Vegan

Why CanPrev Choline 275

One essential nutrient most diets fall short on, in a simple daily capsule.

275 mg of VitaCholine per capsule

Each vegetable capsule delivers 275 mg of VitaCholine (choline L(+) bitartrate), a well-studied, fast-dissolving form of this essential nutrient.

Licensed for liver function

Health Canada NPN 80129261 licenses this product to help support liver function.

Simple, flexible dosing

Take 1 vegetable capsule, 1 to 3 times per day. A 90-capsule bottle covers up to a 90-day supply at the base dose.

Clean, licensed formula

Vegan, non-GMO, gluten-free vegetable capsules, made in Canada in a GMP-compliant facility and licensed by Health Canada, NPN 80129261.

Why people choose CanPrev Choline 275

A closer look at CanPrev Choline 275 - 275 mg of VitaCholine (choline L(+) bitartrate) per capsule, made in Canada.

Liver Function Support

Licensed by Health Canada to help support liver function - the core recommended use for this product.

An Essential Nutrient

Choline is required for normal cell-membrane structure, methyl metabolism, and production of the neurotransmitter acetylcholine.

Bioavailable VitaCholine Form

Uses VitaCholine (choline L(+) bitartrate), a well-studied, fast-dissolving choline source.

Simple, Flexible Dosing

One capsule, 1 to 3 times per day, adjustable to your needs - a 90-capsule bottle covers up to a 90-day supply at the base dose.

CanPrev Choline: Supplement Facts

CanPrev™Choline
English

Each vegetable capsule contains:

  • Choline (VitaCholine, choline L(+) bitartrate)275 mg

Non-Medicinal Ingredients: Hypromellose (capsule), magnesium stearate, microcrystalline cellulose.

Recommended Use or Purpose: Helps to support liver function.

Recommended Dose (Adolescents and Adults, 9 years and over): Take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner. Do not exceed the recommended dose.

Cautions and Warnings: Keep out of reach of children. Do not use if the safety seal is broken. Store in a cool, dry place.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Chaque capsule végétale contient :

  • Choline (VitaCholine, bitartrate de cholineL(+))275 mg

Ingrédients non médicinaux : Hypromellose (capsule), stéarate de magnésium, cellulose microcristalline.

Usage ou fins recommandés : Aide à soutenir la fonction hépatique.

Dose recommandée (adolescents et adultes de 9 ans et plus) : Prendre 1 capsule, 1 à 3 fois par jour, ou selon les indications d'un praticien de soins de santé. Ne pas dépasser la dose recommandée.

Mises en garde et précautions : Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé. Conserver dans un endroit frais et sec.

NPN 80129261

275mg VitaCholine per capsule90 capsules · up to 90-day supplyVegan · Non-GMO · Gluten-freeMade in Canada

Support liver function with an essential nutrient most diets fall short on

Get CanPrev Choline 275 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why people choose CanPrev Choline 275

One essential, often-missed nutrient, licensed to help support liver function - four reasons it's a simple daily add.

Licensed Liver Function Support

Health Canada NPN 80129261 licenses CanPrev Choline 275 to help support liver function.

An Essential, Often-Missed Nutrient

Choline is classified as an essential nutrient, yet research suggests most adults do not meet recommended intake levels from diet alone.

Bioavailable VitaCholine Source

Each capsule uses VitaCholine, a branded, well-studied choline L(+) bitartrate.

Simple Daily Routine

One vegetable capsule, 1 to 3 times per day - flexible dosing in a clean, filler-free format.

How to use

Take 1 capsule

Adolescents and adults (9 years and older): take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner.

Adjust within the label range

Dosing can be adjusted from 1 to 3 capsules daily depending on your needs; do not exceed the recommended dose.

Stay consistent

A 90-capsule bottle provides up to a 90-day supply at 1 capsule per day, or a 30-day supply at 3 capsules per day. Swallow capsules whole with water.

Store properly

Keep out of reach of children. Do not use if the safety seal is broken. Store in a cool, dry place.

What the research says about choline

Peer-reviewed studies and reviews on choline, the ingredient in this formula, shared for education, not as claims about this finished product. CanPrev Choline 275's actual claim is the statement authorized under its Natural Health Product licence, NPN 80129261: helps to support liver function.

Choline & Cognitive Function

Choline named among the few supplements with real evidence for memory

A review of the 18 most common ingredients in over-the-counter memory supplements found current evidence supports a memory benefit from choline, alongside ashwagandha, curcumin and phosphatidylserine, while several other popular ingredients lacked compelling data.

Review
Hersant et al., CNS Drugs (2023)
Choline & Cognitive Function

Choline's role across neurodegenerative disease research

A review of choline metabolism found the nutrient is essential for neurotransmitters, lipid transport and cell-membrane signaling, and that choline supplementation has shown a beneficial effect on measures of memory performance and synaptic functioning in early neurodegenerative disease research.

Review
Eslami et al., Biomolecules (2024)
Choline & Cognitive Function

A related choline compound improved memory over 12 weeks

In a randomized, double-blind, placebo-controlled trial, healthy older adults with age-associated memory impairment who took citicoline (a choline-containing compound) for 12 weeks showed significantly greater improvement in episodic and composite memory scores than those on placebo.

Human RCT
Nakazaki et al., The Journal of Nutrition (2021)
Choline & Brain Chemistry

Choline is the direct precursor of acetylcholine

A review of choline and betaine in health and disease describes choline and its derivatives as components of blood and membrane lipids and as the direct precursor of the neurotransmitter acetylcholine, with choline availability important for neurodevelopment.

Review
Ueland, Journal of Inherited Metabolic Disease (2010)
Choline & Brain Chemistry

A hormone-cholinergic link in cognitive aging

A perspective on estrogen and cognitive decline proposes that estrogen's neuroprotective effects depend heavily on the cholinergic system, and that estrogen strongly induces the pathway the body uses to synthesize its own choline and choline-derived phosphatidylcholine.

Review
Bortz et al., Advances in Nutrition (2023)
Choline & Brain Chemistry

Oral choline changed working-memory brain activity in a pilot study

In a pilot study, postmenopausal women given a single oral dose of choline bitartrate showed altered brain activation and functional connectivity in working-memory-related brain regions on functional MRI compared with placebo, though the small pilot found no difference in task performance.

Human RCT
Dumas et al., Nutrients (2026)
Choline & Liver Function

Low-choline diets caused organ dysfunction, including fatty liver, in a controlled trial

In a randomized controlled feeding trial, most women placed on a very-low-choline diet developed signs of organ dysfunction including fatty liver, and postmenopausal women were markedly more susceptible than premenopausal women, establishing choline's dietary requirement for normal liver function.

Human RCT
Fischer et al., The American Journal of Clinical Nutrition (2010)
Choline & Liver Function

Watching fatty liver develop on a choline-deficient diet

In a controlled inpatient feeding study, healthy women placed on a choline-deficient diet developed measurable fatty liver, with the degree of fat accumulation linked to each individual's gut microbial community and genetics.

Human study
Spencer et al., Gastroenterology (2010)
Choline & Liver Function

Chronic mild choline shortfall reshapes liver fat metabolism

A controlled feeding study found that sustained, suboptimal choline intake similar to habitual levels in roughly 90% of US adults reprogrammed hepatic lipid metabolism and disrupted phospholipid balance, even without any change in total liver fat accumulation.

Preclinical study
Paules et al., Molecular Metabolism (2026)
Choline & Cardiovascular Health

Choline is part of the body's one-carbon metabolism network

A large international pooled analysis of over 32,000 participants examined circulating choline and its related metabolites (betaine, carnitine) alongside cardiometabolic biomarkers, finding these compounds track closely with markers such as creatinine and triglycerides.

Cross-sectional study
Pan et al., The American Journal of Clinical Nutrition (2021)
Choline & Cardiovascular Health

Choline sits within the same metabolic pathway as homocysteine

A study of healthy older New Zealand adults measured choline alongside other one-carbon metabolites and homocysteine, finding these interconnected nutrient pathways showed associations with cardiometabolic health markers such as blood lipids and body composition.

Cohort study
Gillies et al., The Journal of Nutrition (2023)
Choline & Cardiovascular Health

Mapping choline's place among one-carbon nutrients

A pooled analysis of over 16,000 participants across nine European studies examined dietary intake and blood levels of one-carbon-metabolism nutrients, including choline, betaine and homocysteine, finding choline intake was among the strongest contributors to the dietary-intake pattern in this network.

Cohort study
Park et al., Nutrients (2025)
Choline & Prenatal Nutrition

More maternal choline, faster infant processing speed

In a randomized, double-blind, controlled feeding study, infants born to mothers who consumed roughly twice the recommended choline intake during the third trimester showed significantly faster information-processing speed through their first year than infants of mothers at the recommended intake.

Human RCT
Caudill et al., FASEB Journal (2018)
Choline & Prenatal Nutrition

Maternal choline supported infant growth and recognition memory

In a randomized, double-blind, placebo-controlled trial, infants of mothers given a high daily choline dose from mid-pregnancy showed better eyeblink-conditioning performance, catch-up growth, and better visual recognition memory at 12 months than the placebo group.

Human RCT
Jacobson et al., Alcoholism: Clinical and Experimental Research (2018)
Choline & Prenatal Nutrition

A clinical review on choline through pregnancy and lactation

A review of meta-analyses and systematic reviews from the past decade found consistent support for choline's role in neurological development, brain and liver function, and reduced neural tube defect risk during pregnancy, while noting most pregnant and lactating women fall short of intake recommendations.

Systematic review
Derbyshire, Nutrients (2025)
Choline Intake Gaps

The majority of adults fall short of the recommended choline intake

In the Atherosclerosis Risk in Communities study of over 15,000 US adults, 94% of men and 89% of women reported a dietary choline intake below the proposed Adequate Intake level.

Cohort study
Bidulescu et al., Nutrition Journal (2009)
Choline Intake Gaps

Most pregnant women in the US do not meet choline recommendations

A nationally representative analysis of US pregnant women's usual dietary intake found a substantial share did not meet recommendations for several nutrients, including choline, even accounting for dietary supplement use.

Cross-sectional study
Bailey et al., JAMA Network Open (2019)
Choline Intake Gaps

Choline ranks among the most under-consumed nutrients in America

A nutrient-prioritization analysis of the US population found choline, alongside dietary fiber and vitamin D, showed an inadequacy rate exceeding 90% across different life stages, identifying it as a priority nutrient for public health attention.

Cross-sectional study
Starck et al., Nutrients (2025)
Choline Safety & Metabolism

Rethinking TMAO as a simple toxin

A perspective from choline researchers noted that recent data challenge the interpretation of trimethylamine N-oxide (TMAO), a gut-microbial choline metabolite, as a direct causal toxin, instead positioning it as more of a marker of kidney function.

Review
Paules et al., Nutrients (2025)
Choline Safety & Metabolism

A dietary choline source did not raise TMAO to a concerning level

In a randomized controlled trial, healthy middle-aged and older adults given 12 weeks of egg-derived phosphatidylcholine (a dietary choline source) at various doses did not see their blood TMAO levels approach the range associated with clinical risk.

Human RCT
Wang et al., Lipids in Health and Disease (2026)
Choline Safety & Metabolism

Distinguishing choline itself from its downstream metabolites in pregnancy safety research

In a birth-cohort study of nearly 2,000 pregnant women, it was TMAO levels, not choline itself, that were linked to a higher risk of hypertensive disorders of pregnancy, while a related metabolite (betaine) was linked to lower risk, underscoring why individual one-carbon metabolites are studied separately.

Cohort study
Qian et al., BMC Pregnancy and Childbirth (2026)
Choline & Healthy Aging

A choline-metabolism gene variant tracks with hippocampal volume after menopause

A study of postmenopausal women found that a genetic variant affecting the enzyme that starts choline synthesis (choline kinase alpha) was associated with differences in hippocampal brain volume and delayed memory scores.

Human study
Myers et al., Heliyon (2023)
Choline & Healthy Aging

A cholinergic route to protecting the aging brain after estrogen decline

In an animal model of estrogen decline after menopause, treatment that restored estrogen signaling increased expression of the enzyme that produces acetylcholine in the memory-related hippocampus and improved spatial learning and memory.

Preclinical study
Chen et al., International Journal of Molecular Sciences (2023)
Choline & Healthy Aging

Choline's proposed role across a lifetime of brain health

A narrative review describes choline as a critical, often overlooked nutrient with a well-characterized role in early neurodevelopment and a plausible, though not yet fully established, role in cognitive function across the lifespan, via mechanisms including epigenetic programming.

Review
Boldon et al., Nutrition Research (2026)

Frequently asked questions

What is CanPrev Choline 275?

It is a Health Canada licensed Natural Health Product (NPN 80129261) delivering 275 mg of VitaCholine (choline L(+) bitartrate) per vegetable capsule.

What is it licensed for?

This product's Health Canada licence covers one recommended use: it helps to support liver function.

How do I take it?

Adolescents and adults (9 years and older) take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner.

Is it vegan?

Yes. The vegetable capsule and formula are vegan, non-GMO, and free from gluten, dairy, soy, wheat, yeast, sugar and preservatives.

What else is in each capsule besides choline?

Only the vegetable capsule shell and two non-medicinal ingredients: hypromellose, magnesium stearate and microcrystalline cellulose.

Why is choline considered important?

Choline is an essential nutrient the body needs for normal cell-membrane structure, methyl metabolism and the production of the neurotransmitter acetylcholine; most people do not get enough from diet alone. These are general facts about the ingredient, not claims about this specific product beyond its licensed liver-function use.

Can I take it if I am pregnant or breastfeeding?

This product's label carries no pregnancy-specific caution beyond the standard cautions below. As with any supplement, consult a health care practitioner before use if you are pregnant, breastfeeding, or under the care of a physician for a medical condition.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

275mg VitaCholine per capsule90 capsules · up to 90-day supplyVegan · Non-GMO · Gluten-freeMade in Canada

Support liver function with an essential nutrient most diets fall short on

Get CanPrev Choline 275 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80129261. Helps to support liver function. The research summaries below concern choline, the ingredient in this formula, and are educational; they are not claims about this finished product beyond its licensed recommended use. Read and follow the label. Keep out of reach of children. Do not use if the safety seal is broken. Results may vary.

Important information

Safety Information

Cautions and Warnings: Keep out of reach of children. Do not use if the safety seal is broken. Store in a cool, dry place.

Indications

Recommended Use or Purpose: Helps to support liver function.

Ingredients

Medicinal Ingredients (per 1 vegetable capsule): Choline (VitaCholine, choline L(+) bitartrate) 275 mg. Non-medicinal Ingredients: Hypromellose (capsule), magnesium stearate, microcrystalline cellulose. Vegan, non-GMO and gluten-free. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adolescents and Adults, 9 years and over): Take 1 capsule, 1 to 3 times per day, or as directed by a health care practitioner. Do not exceed the recommended dose.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.